>1400

Education event attendees

Career Day

> 50 %

Acceptance rate to graduate programs

Mentorship for Prospective Students in Genetic Counseling

Interns 2013-2023

49

Summer interns

Internship Program in Genetic Counseling and Bioinformatics

Applying to Genetic Counseling Graduate Programs
Ask an Expert

Questions about Genetics?

Ask a member of the Iowa Institute of Human Genetics your genetics-related question. Complete this online form and we will be happy to assist you

Students studying outdoors at Iowa Memorial Union

Genetics Cluster Initiative

Genetics transcends departments, colleges and disciplines and generates both needs and services in the basic sciences, health care, bioethics, law, bioinformatics and communications.

Recent Publications

CF airway epithelia display exaggerated host defense responses and prolonged cilia loss during RSV infection

Sunday, February 16, 2025
Jennifer A Bartlett
CONCLUSIONS: These findings further our understanding of innate immune dysfunction in the CF airway epithelium and suggest that virus-induced cilia injury may further compromise host defenses in CF airways.

Profiles of Exosomal microRNAs in Joint Cells and Candidate microRNAs for Cartilage Regeneration

Thursday, February 13, 2025
Venkateswaran Ganesh
The activation of chondrogenic progenitor cells (CPCs) in articular cartilage during a traumatic injury is vital for cartilage regeneration. Although our understanding of the mechanisms underlying CPC chondrogenic activation remains incomplete, there is evidence that exosomal microRNAs (miRNAs or miRs) are involved in tissue healing due to their regulating role of posttranscriptional gene expressions. In this study, we profiled enriched and differential expression of miRNAs in exosomes derived...

The oxygen level in air directs airway epithelial cell differentiation by controlling mitochondrial citrate export

Friday, January 24, 2025
Bo Ram Kim
Oxygen controls most metazoan metabolism, yet in mammals, tissue O(2) levels vary widely. While extensive research has explored cellular responses to hypoxia, understanding how cells respond to physiologically high O(2) levels remains uncertain. To address this problem, we investigated respiratory epithelia as their contact with air exposes them to some of the highest O(2) levels in the body. We asked how the O(2) level in air controls differentiation of airway basal stem cells into the ciliated...

The Impact of Cell-Intrinsic STAT6 Protein on Donor T Cell-Mediated Graft-Versus-Tumor Effect

Saturday, January 11, 2025
Xiaoqun Guan
Bone marrow transplantation (BMT) is mainly performed to restore an anti-tumor immune response, called the graft-versus-tumor (GVT) effect, against leukemia, myeloma and lymphoma. This GVT reactivity is driven by donor T cells, and it can also cause lethal graft-versus-host disease (GVHD). We previously demonstrated that the colonization of mice with helminths preserves the GVT response while suppressing GVHD. As the T helper-2 (Th2) pathway is critical to helminthic immune regulation, we asked...

Spatial differences in gene expression across the dorsal raphe nucleus in a model of early Alzheimer's disease

Monday, November 25, 2024
Louis J Kolling
CONCLUSIONS: Map2k3os may serve regulatory roles relevant for tau phosphorylation and warrants further investigation to characterize its interactions. Overall, this report demonstrates the power of large-scale spatial transcriptomics technologies, while underscoring the need for convergent-data validation to overcome their limitations.

Events

Women In Micro & Immuno Coffee Hour

Monday, January 13, 11:00am to Monday, December 8, 2025 12:00pm
Carver Biomedical Research Building
Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion! This is open to ALL — students, staff, postdocs, and faculty interested in promoting women in science. Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.
Molecular Medicine Interdisciplinary Program Thesis Defense Seminar: Jesse Rose promotional image

Molecular Medicine Interdisciplinary Program Thesis Defense Seminar: Jesse Rose

Monday, February 17, 2025 11:00am
Medical Education Research Facility
Jesse Rose is a current student of the Molecular Medicine Graduate Program, PhD Candidate, and is in Dr. Matt Potthoff's laboratory.
Canceled - Department of Microbiology and Immunology - Gwendalyn Randolph, PhD promotional image

Canceled - Department of Microbiology and Immunology - Gwendalyn Randolph, PhD

Tuesday, February 18, 2025 3:00pm to 4:00pm
Bowen Science Building
Canceled