Career Opportunties


Postdoctoral Research Scholar

Requisition #2971

​Yeaman Lab

The Yeaman laboratory in the Department of Anatomy and Cell Biology at the University of Iowa is seeking a motivated, focused and skilled Postdoctoral Fellow. The Yeaman group is interested in identifying molecular mechanisms responsible for biogenesis of epithelial cell polarity (publications in Cell, Molecular Cell, Nature Cell Biology, J. Cell Biol., etc). We study details of fundamental cellular processes, such as intercellular adhesion, cytoskeletal remodeling and membrane trafficking, that are at the foundation of tissue development and organogenesis.  Our focus is on the Exocyst, a multi-functional, allosterically regulated scaffold, and Ral GTPases, which regulate Exocyst functions by facilitating association or disassociation with additional proteins.  We utilize CRISPR/Cas9 gene editing, along with mouse models, 2D and 3D cell culture models, cutting edge cell imaging technologies and biochemical assays to understand how Exocyst protein assemblies function during cell growth and differentiation, motility and cell division. We are performing focused structure-function studies in efforts to understand how specific mutations in genes encoding Exocyst and Ral proteins contribute to human diseases including cancers, diabetes and ciliopathies. The University of Iowa Carver College of Medicine is a highly ranked biomedical research institute. The Yeaman laboratory is located in a state-of-the-art facility that features a collaborative atmosphere to foster innovation.

Qualifications: Interested candidates should have obtained a Ph.D. or M.D. degree with a strong background in molecular biology, cell biology and biochemistry. The ideal candidate will have proven talent to work independently with excellent interpersonal and communication skills.

Desired:

Solid knowledge in Cell and Molecular Biology and Biochemistry;

Extensive experience working with mammalian cell lines and primary cells (ideally polarized epithelial cultures grown on Transwells or in Matrigel);

Extensive experience with PCR, RT-PCR, molecular cloning, CRISPR/Cas9;

Experience with TIRF, super-resolution microscopy, confocal microscopy and electron microscopy;

Experience in mouse handling, genotyping, mouse surgeries, tissue dissection.

To apply for this position visit our website at http://jobs.uiowa.edu; requisition #2971.  The University of Iowa is an Equal Opportunity/Affirmative Action Employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran. Applicants’ credentials are subject to verification.


Postdoctoral position- Synaptic control of information transmission

Requisition 2920

Samuel Young Laboratory

There is an open post-doctoral position for an enthusiastic and highly motivated individual in the laboratory of Samuel Young (https://young.lab.uiowa.edu/) at the University of Iowa Carver College of Medicine, Iowa City, IA.The Young laboratory is focused on the fundamental question: “How do synapses enable neuronal circuits to transmit a wide diversity of information?”  Outcomes from our work will define the molecular principles that govern how synaptic properties drive neuronal circuit output, which underpins organism behavior.

Usingthe calyx of Held presynaptic terminal as the primary model in combination with cutting edge viral vector technology and mouse models, we are 1) determining the mechanisms for fast auditory signalling 2) defining the molecular mechanisms that regulate Cav2 subtypes levels and organization in the presynaptic terminal and their roles in defining neural circuit function. 

The ideal candidate must have a PhD in a related scientific discipline and be well trained in electrophysiology and patch-clamp techniques. In addition, a background in molecular biology, advanced microscopy techniques, or hearing sciences is preferred. The candidate must have at least one first author publication. 

To apply for this position visit our website at http://jobs.uiowa.edu; requisition #2920. Interested candidates should submit their Curriculum Vitae, a concise statement of research accomplishments and interests and complete contact information for at least three references. The Young laboratory is affiliated with the Department of Anatomy and Cell Biology at the University of Iowa and located within the Pappajohn Biodiscovery Building. Dr. Young is a member of the Iowa Neuroscience Institute and has a joint appointment within the Department of Otolaryngology. The PI is committed to the career development of trainees. 

Iowa City is a vibrant mid-sized city that perennially ranks in the top 10 as a "Best Place to Live" http://www.iowacityareadevelopment.com/live/rankings.aspx). It is the first UNESCO City of Literature in the U.S. and hosts a wide variety of cultural, artistic, and sporting events year-round.

University of Iowa Employment: The University of Iowa prohibits discrimination in employment, educational programs, and activities on the basis of race, creed, color, religion, national origin, age, sex, pregnancy, disability, genetic information, status as a U.S. veteran, service in the U.S. military, sexual orientation, gender identity, associational preferences, or any other classification that deprives the person of consideration as an individual. The university also affirms its commitment to providing equal opportunities and equal access to university facilities. For additional information on nondiscrimination policies, contact the Director, Office of Equal Opportunity and Diversity, The University of Iowa, 202 Jessup Hall, Iowa City, IA, 52242-1316, 319-335-0705 (voice), 319-335-0697 (TDD), diversity@uiowa.edu


Assistant Research Scientist

Requisition #72662

The Yang laboratory at the department of Anatomy and Cell Biology, the Fraternal Order of Eagles Diabetes Research Center at the University of Iowa is seeking a motivated, focused and skilled Assistant Research Scientist. The Yang group is interested in identifying the molecular components of integration between stress responses that are in play in obesity and diabetes at the cellular and organismic levels (publications in Science, Cell Metabolism and Diabetes. https://yang.lab.uiowa.edu). The Assistant Research Scientist will be focused on the interaction between inflammatory stress and organelle stress response biology across multiple research areas of interest of Yang lab. The candidate will apply expertise in immunology, physiology, pathophysiology of oxidative stress-mediated inflammatory diseases to identify and characterize genes, networks and pathways involved in normal and obese mouse. This information will be used to understand the molecular basis of obesity pathology and the mechanism of action of drugs, and ultimately be used for selection of drug targets. The candidate will contribute to new or continuing research grant applications, and writing progress reports required by funding agencies. The candidate will also in charge of mentoring graduate students and providing functional and/or administrative supervision for staffs in the lab.  Requires the academic knowledge of a Ph.D. (and/or M.D.) with at least 5 years of progressively independent post-graduate research experience in the area of metabolic diseases research. The ideal candidate will have proven talent to work independently with excellent interpersonal and communication skills; Have solid knowledge and working experience in animal and tissue culture models to study inflammatory responses as well as determined the mechanisms behind chronic inflammation-induced insulin resistance; Skilled in biochemistry assays for measuring oxidative stress, apoptosis, tissue injury; Extensive experience in isolating primary macrophage and islets from mice; Extensive experience with sub-clone, viral construction, as well as overexpression/suppression of target gene expression in mouse model; Extensive experience with flow cytometry, confocal microscopy and EM; Profound experience in genetic mouse models, mouse metabolic profiling, animal handling, mouse surgeries, tissue dissection; and Strong ability in working independently on research tasks, and analyzing data for relevance and data integrity. To apply for this position visit our website at http://jobs.uiowa.edu; requisition #72662.  Application deadline is May 1, 2018.  The University of Iowa is an Equal Opportunity/Affirmative Action Employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.  Applicants’ credentials are subject to verification.


Combined Teaching and Research Postdoctoral position in Developmental Biology

The Department of Anatomy & Cell Biology

Requisition #2855

A postdoctoral position is immediately available in the Tootle Lab at the University of Iowa, Carver College of Medicine. The position entails ~80% research and ~20% teaching. The teaching experience will entail designing an online development/human embryology course for both master’s and Ph.D. candidates, and a journal club on related material for only the Ph.D. students. Mentorship in curriculum design and instruction will be provided by Dr. Darren Hoffmann, a recipient of numerous teaching awards.

Research will be performed in the Tootle lab, which focuses on prostaglandin regulation of actin – both within the cytoskeleton and in the nucleus. The primary model used is Drosophila oogenesis. The enzymes that make prostaglandins are the targets of non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen. Prostaglandins are lipid signals that play critical roles in human health and disease, including pain/inflammation, reproduction, heart health and disease, and cancer. Importantly, actin is also implicated in these processes. Therefore, the mechanisms by which prostaglandins regulate actin – both in the cytoplasm and in the nucleus – are likely conserved from flies to humans.

For more information on the Tootle lab, please see: www.tootlelab.com. The Tootle Lab is located within the Anatomy and Cell Biology Department (https://www.medicine.uiowa.edu/acb/).

The University of Iowa is located in Iowa City – a fun, college town that was ranked no. 3 for best places to live in America by Outside Magazine (2015). For more information on Iowa City, see http://livability.com/ia/iowa-city/community/why-iowa-city-iowa-top-100-....

Requirements: PhD in biological sciences and less than 3 years postdoctoral experience. Technical experience in one or more of the following areas preferred: molecular biology, basic protein biochemistry, genetics, and microscopy.  Excellent interpersonal and communication skills are required.   

To apply for this position visit our website at http://jobs.uiowa.edu requisition #2855.  Applications should include: CV, List of three references, Graduate transcript (unofficial is fine), and a cover letter. The University of Iowa is an Equal Opportunity/Affirmative Action Employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.  Applicants’ credentials are subject to verification.