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Xingshen Sun

Portrait
Research Assistant Professor of Anatomy and Cell Biology

Contact Information

Primary Office
1-675F BSB
51 Newton Road
Iowa City, Iowa 52242
319-335-6759

Education

BS, Animal Science, Yanbian Agricultural University
MS, Animal Reproduction, Northeast Agricultural University
Postdoctoral Fellow, University of Iowa

Research Summary


My research interests focus on the molecular basis of inherited and environmentally induced diseases, the development of human disease animal models, and therapies for these disorders. Included are four major areas: 1) molecular and cellular biology of ferret preimplantation embryos that relates to the development of genic editing ferrets, the generation of ferret embryonic stem cells, and the production of induced pluripotent stem cells (iPS); 2) developmental biology of the pancreas, specifically the mechanism and signal pathway of pancreatic regeneration that relates to the pathogenesis and treatment of cystic fibrosis-related diabetes and pancreatitis-related diabetes (Type 3c diabetes); 3) somatic cell reprogramming that relates to the development of cell-based therapy of human diseases such as cystic fibrosis and diabetes; 4) CRSPR/Case gene editing that relates to the gene therapy and generation of animals models.