New Department Publications

Molecular Biology of the Cell cover image

 

 

Neuroscience Letters

“Activation of cyclic GMP-dependent protein kinase blocks alcohol-mediated cell death and calcium disruption in cerebellar granule neurons.” 

Nicholas Pantazis

 


 

Journal of Neuroscience

“Hand Motor Recovery Following Extensive Frontoparietal Cortical Injury Is Accompanied by Upregulated Corticoreticular Projections in Monkey.”

Marc Pizzimenti

 


 

eLife

Orphan receptor GPR158 controls stress-induced depression

Samuel M. Young

 

 


 

Diabetes

S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy 

Ling Yang

 

 


 

Journal of Cystic Fibrosis

Animal and model systems for studying cystic fibrosis 

Bradley Rosen

 

 


Brad A. Amendt

 

Scientific Reports

Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development  

Brad Amendt

 

 


 

The American Journal of Pathology

Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets

Pavana Rotti

 

 


 

FEBS Journal

Liver function and dysfunction – a unique window into the physiological reach of ER stress and the unfolded protein response 

Thomas Rutkowski

 


 

Cell Reports

A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis

Adam Dupuy

 


Brian Paul

 

Journal of Dental Research

ARHGAP29 Mutation Is Associated with Abnormal Oral Epithelial Adhesions.

Brian Paul

 

 


Robert Cornell

 

DEVELOPMENTAL DYNAMICS​

Zebrafish as Models for Developmental Disease & Repair

Robert Cornell

 

 




 

Journal of Virology

Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis

Ziying Yan

 

 


 

Small GTPases

An emerging role for IQGAP1 in tight junction control​

Chuck Yeaman

 


 

Oncogene

A novel HER2 gene body enhancer contributes to HER2 expression

Qi (Lucy) Liu

 

 


Hank Qi

 

Biochimica et Biophysica Acta

Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3.

Hank Qi

 

 


 

Frontiers in Cell and Developmental Biology

Probing Functional Changes in Exocyst Configuration with Monoclonal Antibodies

Chuck Yeaman

 


 

Frontiers in Molecular Neuroscience

The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster

C. Andrew Frank

 

 


Brad A. Amendt

 

American Journal of Orthodontics and Dentofacial Orthopedics

Candidate gene analyses of 3-dimensional dentoalveolar phenotypes in subjects with malocclusion

Brad A. Amendt

 

 


 

PLOS Genetics

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF

Hannah E. Seberg

 

 


 

Molecular and Cellular Biology

Role of the Exocyst Complex Component Sec6/8 in Genomic Stability​

Chuck Yeaman

 


Brad A. Amendt

 

Developmental Cell

Mesenchymal MicroRNA Function Branches Out.

Brad A. Amendt

 

 


Adam Dupuy

 

Cancer Research

Molecular and Cellular PathobiologyA Transposon-based Analysis Reveals RASA1Is Involved in Triple-Negative Breast Cancer

Adam Dupuy

 

 


 

American Journal of Respiratory Cell and Molecular Biology

A Heterotopic Xenograft Model of Human Airways for Investigating Fibrosis in Asthma

Yulong Zhang

 

 


 

 

American Journal of Respiratory Cell and Molecular Biology

Multipotent Myoepithelial Progenitor Cells Are Born Early During Airway Submucosal Gland Development.

Preston Anderson

 


 

Journal of Virology

Parvovirus Expresses a Small Noncoding RNA That Plays an Essential Role in Virus Replication.

Ziying Yan

 

 




 

Nature Communications

Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting


Huan Liu

 


Robert Cornell

 

Birth Defects Research

Exome sequencing provides additional evidence for the involvement of ARHGAP29 in Mendelian orofacial clefting and extends the phenotypic spectrum to isolated cleft palate

Robert Cornell

 

 


Martin Cassell

 

Hypertension

Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension


Martin Cassell

 

 


Brad A. Amendt

 

Birth Defects Research

Exome sequencing provides additional evidence for the involvement of ARHGAP29 in Mendelian orofacial clefting and extends the phenotypic spectrum to isolated cleft palate

Brad A. Amendt

 


Adam Dupuy

 

International Journal of Cancer

Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms

Adam Dupuy

 

 


Martine Dunnwald

 

Birth Defects Research

Exome sequencing provides additional evidence for the involvement of ARHGAP29 in Mendelian orofacial clefting and extends the phenotypic spectrum to isolated cleft palate

Martine Dunnwald

 

 


Fluids and Barriers of the CNS

Structural defects in cilia of the choroid plexus, subfornical organ and ventricular ependyma are associated with ventriculomegaly.

Chuck Yeaman

 


Tom Rutkowski

 

eLife

Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

Tom Rutkowski

 

 


John Engelhardt

 

Pancreas

Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop


John Engelhardt

 

 


Darren Hoffmann

 

Medical Science Educator

Content Evaluation, Usage Profile, and Student Preferences Related to a Medical Student Wiki for Student-Authored Learning Resources (Carverpedia)

Darren Hoffmann

 

 


Peterson Maina

 

Oncotarget

c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer

Peterson Maina

 

 


Hank Qi

 

Nucleic Acids Research

Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis

Hank Qi

 




 

PLos One

Sec5 and Exo84 mediate distinct aspects of RalA-dependent cell polarization.

Chuck Yeaman

 


Daniel Kelpsch

 

Molecular Biology of the Cell (MBoC)

Fascin regulates nuclear actin during Drosophila oogenesis

Daniel Kelpsch

 

 


Mason Sweat

 

Development

Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Mason Sweat

 

 


Botond Banfi

 

The Journal of Biological Chemistry

NADPH Oxidases Are Essential for Macrophage Differentiation

Botond Banfi PhD

 

 


Steve Eliason

 

PLoS One

MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation

Steve Eliason

 

 


Tina Tootle

 

Developmental Cell

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells

Tina Tootle PhD.

 


Adam Dupuy

 

Development

Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Adam-Dupuy, PhD.

 


Dr. John Engelhardt

 

The Journal of Biological Chemistry

NADPH Oxidases Are Essential for Macrophage Differentiation

John Engelhardt, PhD.

 


Yaling Yi

 

American Journal of Respiratory and Critical Care Medicine

Abnormal Glucose Tolerance in Infants and Young Children with Cystic Fibrosis

Yaling Yi

 


 

American Journal of Respiratory Cell and Molecular Biology

Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.

​Idil Evans

 


 

Basal Ganglia

The vulnerable ventral tegmental area in Parkinson’s disease

Martin Cassell, PhD.


 

​Neuropharmacology

Homeostatic plasticity at the Drosophila neuromuscular junction

C. Andrew Frank, PhD.

 


The American Journal of Pathology

Gastrointestinal Pathology in Juvenile and Adult CFTR-Knockout Ferrets 

Xingshen Sun

 

 


 

Frontiers

How voltage-gated calcium channels gate forms of homeostatic synaptic plasticity

C. Andrew Frank, PhD.

 


 

ATS Journals

Lung Phenotype of Juvenile and Adult Cystic Fibrosis Transmembrane Conductance Regulator–Knockout Ferrets

Xingshen Sun

 


Journal of Muscle Research and Cell Motility

Characterizations of myosin essential light chain's N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to sinusoidal length alterations.

Li Wang

 


 

Foot & Ankle International

Vascular Disruption of the Talus: Comparison of Two Approaches for Triple Arthrodesis

Dr. Marc Pizzimenti


 

Journal of Investigative Dermatology 

Ectopic Expression of Zmiz1 Induces Cutaneous Squamous Cell Malignancies in a Mouse Model of Cancer 

Laura Rodgers and Dr. Adam Dupuy


 

PLOS

Turning Semicircular Canal Function on Its Head: Dinosaurs and a Novel Vestibular Analysis

Dr. Justin Sipla


 

The Journal of Immunology 

Adaptive Immunity Does Not Strongly Suppress Spontaneous Tumors in a Sleeping Beauty Model of Cancer

Laura Rodgers and Dr. Adam Dupuy


Cerebrovascular Diseases

Dimensions of Subcortical Infarcts Associated with First- to Third-Order Branches of the Basal Ganglia Arteries

Dr. Martin Cassell

 


 

Journal of Muscle Research and Cell Motility

Characterizations of myosin essential light chain's N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to sinusoidal length alterations.

Li Wang and Dr. Masataka Kawai

 


 

Hypertension

Angiotensin Type 1a Receptors in the Subfornical Organ Are Required for Deoxycorticosterone Acetate-Salt Hypertension

Dr. Martin Cassell