Graduate Student
Address: 4-610 BSB
Phone: (319) 335-7501
Email: kyle-powers@uiowa.edu

Mentor: Todd Washington, PhD

Undergraduate Institution: The University of Ilinois at Urbana-Champaign

Research Description

Probing dynamics of disordered regions in translesion synthesis protein complexes by tandem computational and single molecule approaches

Awards

Center for Biocatalysis and Bioprocessing Sponsored NIH Predoctoral Training Fellow in Biotechnology (Ruth L. Kirschstein National Research Service Award )
2013-14 and 2014-2015

Publications

Boehm, EM, Powers, KT, Kontratick, CM, Spies M, Houtman JCD, and Washington, MT. The Proliferating Cell Nuclear Antifen (PCNA)-interacting Protin (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1. JBC. 2016.

LuCore, DS, Litman JM, Powers, KT, Gao, S, Lynn, AM, Tollefson, WTA, Fenn, TD, Washington, MT, and Schniders, JM. Dead-End Elimination with a Polarizable Force Field Repacks PCNA Moels from Low-Resolution x-Ray Diffraction into Atomic Resolution Structures. Biophysical Journal.  2015.

Kondratick, CM, Boehm, EM, Dieckman, LM, Powers, KT, Sanchez JC, and Washington, MT. Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Sythesis. PLOS ONE.  2016.