Janet A. Fairley, MD, FAAD

Portrait
Chair, John S. Strauss Professor and Head
Professor of Dermatology

Contact Information

Office: 40040 Pomerantz Family Pavilion
200 Hawkins Drive
Iowa City, IA 52242
319-356-3609

Education

BS, Zoology, Michigan State University
MD, Medicine, University of Michigan Medical School

Internship, Hennepin County Medical Center
Resident, Dermatology, University of Michigan
Fellow, NIH Research, Cell Physiology, Dermatology, University of Michigan

Licensure and Certifications

State of Iowa Medical License - Iowa Board of Medicine
Board Certified - American Board of Dermatology
Board Certified - National Board of Medical Examiners
State of Michigan Medical License - Michigan Board of Medicine

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Translational Biomedicine

Research Summary

The overall goal of the current research in my laboratory is to better understand the pathogenesis of the organ-specific autoimmune blistering diseases, such as bullous pemphigoid. Bullous pemphigoid (BP) is an blistering skin disease skin characterized by development of autoantibodies against BP180, a cell-substrate attachment protein. Early studies of the pathogenesis of BP were focused on autoantibodies of the IgG class; however, findings from our work and others have made it clear that IgE class autoantibodies also play a critical role in this disease process. We have shown that 90% of BP patients produce IgE autoantibodies that target the same small antigenic region of BP180 (termed NC16A) that is recognized by IgG autoantibodies. Further, BP IgE, when passively transferred into a xenograft murine model, can replicate the early phase of BP lesion development. This was the first demonstration of the pathogenicity of human IgE in an autoimmune disease. Treatment of basophils isolated from BP patients with the NC16A peptide was shown to induce specific degranulation of the cells, suggesting one mechanism by which IgE may contribute to lesion development. Recently we have utilized our research on IgE for the basis of a clinical trials of anti-IgE therapy in BP. Our future goals are to further delineate the role of IgE autoantibodies and effectors cells such as eosinophils and mast cells in BP and to utilize this information to identify additional novel therapies for autoimmune diseases.

As a physician-scientist one of my major goals is to translate findings from the laboratory into improved diagnostics and or therapies for patients.

Publications

Hammel, J. A., Roth, G. M., Ferguson, N. & Fairley, J. A. (In Press). Lower extremity ecchymotic nodules in a patient being treated with ibrutinib for chronic lymphocytic leukemia. JAAD Case Rep, 3(3), 178-9.

Messingham, K. A., Aust, S., Helfenberger, J., Parker, K. L., Schultz, S., McKillip, J., Narayanan, N. S. & Fairley, J. A. (2016). Autoantibodies to Collagen XVII Are Present in Parkinson's Disease and Localize to Tyrosine-Hydroxylase Positive Neurons. J Invest Dermatol, 136(3), 721-3. PMID: 27015458.

Messingham, K. N., Randall, G. & Fairley, J. (2016). Exploring mechanisms of IgE-mediated autoimmunity through the lens of Bullous pemphigoid. G Ital Dermatol Venereol. PMID: 26959553.

Messingham, K. N., Wang, J. W., Holahan, H. M., Srikantha, R., Aust, S. C. & Fairley, J. A. (2016). Eosinophil localization to the basement membrane zone is autoantibody- and complement-dependent in a human cryosection model of bullous pemphigoid. Exp Dermatol, 25(1), 50-5. PMID: 26475989.

Kinn, P. M., Holdren, G. O., Westermeyer, B. A., Abuissa, M., Fischer, C., Fairley, J. A., Brogden, K. A. & Brogden, N. K. (2015). Age-dependent variation in cytokines, chemokines, and biologic analytes rinsed from the surface of healthy human skin. Sci Rep, 2(5), 10472. PMID: 26035055.

Murrell, D. F., Marinovic, B., Caux, F., Prost, C., Ahmed, R., Wozniak, K., Amagai, M., Bauer, J., Beissert, S., Borradori, L., Culton, D., Fairley, J. A., Fivenson, D., Jonkman, M. F., Marinkovich, M. P., Woodley, D., Zone, J., Aoki, V., Bernard, P., Bruckner-Tuderman, L., Cianchini, G., Venning, V., Diaz, L., Eming, R., Grando, S. A., Hall, R. P., Hashimoto, T., Herrero-Gonzalez, J. E., Hertl, M., Joly, P., Karpati, S., Kim, J., Chan Kim, S., Korman, N. J., Kowalewski, C., Lee, S. E., Rubenstein, D. R., Sprecher, E., Yancey, K., Zambruno, G., Zillikens, D., Doan, S., Daniel, B. S. & Werth, V. (2015). Definitions and outcome measures for mucous membrane pemphigoid: recommendations of an international panel of experts. J Am Acad Dermatol, 72(1), 168-74. PMID: 25443626.

Messingham, K. A., Holahan, H. M. & Fairley, J. A. (2014). Unraveling the significance of IgE autoantibodies in organ-specific autoimmunity: lessons learned from bullous pemphigoid. Immunol Res, 59((1-3)), 273-8. PMID: 24845463.

Yu, L. L., Crew, A. B., Messingham, K. A., Fairley, J. A. & Woodley, D. T. (2014). Omalizumab therapy for bullous pemphigoid. J Am Acad Dermatol, 71(3), 468-74. PMID: 24954907.

Holahan, H. M., Farah, R. S., Selby, J. C. & Fairley, J. A. (2014). Erythema annulare-like acantholytic dermatosis: A subset of pemphigus folia. Br J Dermatol, 171(6), 1558-9. PMID: 24836841.

Messingham, K. N., Holahan, H. M., Frydman, A. S., Fullenkamp, C., Srikantha, R. & Fairley, J. A. (2014). Human Eosinophils Express the High Affinity IgE Receptor, FceRI, in Bullous Pemphigoid. J. Zhang (Eds.) (Vols. 9). (9), pp. e107725. PLoS One. PMID: 25255430.

Kelchen, M. N., Holdren, G. O., Farley, M. J., Zimmerman, M. B., Fairley, J. A. & Brogden, N. K. (2014). Optimization of Impedance Spectroscopy Techniques for Measuring Cutaneous Micropore Formation after Microneedle Treatment in an Elderly Population. Pharm Res, 31(12), 3478-86. PMID: 24947437.

Fairley, J. A., Krueger, G. G., Lessin, S. R., Leyden, J. J., McBurney, E. I., Orlow, S. J., Tharp, M. D., Voorhees, J. J., Wintroub, B. U. & Yancey, K. B. (2013). The Dermatology Foundation: partnerships and programs focused on the future. J Invest Dermatol, 133(4), 861-2. PMID: 23486423.

Fairley, J. A., Bream, M., Fullenkamp, C. A., Syrbu, S. I., Chen, M. & Messingham, K. N. (2013). Missing the target: characterization of bullous pemphigoid patients who are negative using the BP180 enzyme-linked immunosorbant assay. J Am Acad Derm, 68(3), 395-403. PMID: 23083837.

Hall, R. P., Streilein, R. D., Hannah, D. L., McNair, P. D., Fairley, J. A., Ronaghy, A., Edhegard, K. D. & Levesque, M. C. (2013). Association of serum B-cell activating factor level and proportion of memory and transitional B cells with clinical response after rituximab treatment of bullous pemphigoid patients. J Invest Dermatol, 133(12), 2786-8. DOI: 10.1038/jid.2013.236.

Hochwalt, P. C., Asarch, A., Stone, M. S. & Fairley, J. A. (2012). Numerous skin-colored papules on the face and neck. PMID: 22801626.

Messingham, K., Vanderah, E. M., Onoh, A., Giudice, G. J. & Fairley, J. A. (2012). Functional characterization of an IgE-class monoclonal antibody specific for the bullous pemphigoid autoantigen, BP180. PMID: 22509915.

Fairley, J. A. (2012). Monoclonal antibody BP180 against bullous pemphigoid antigen-2 type XVII collagen. Hybridoma (Larchmt), 31(2), 146-7. PMID: 22509921.

Hall, R., Fairley, J. A., Woodley, D. T. & Werth, V. (2012). Treatment of patients with pemphigus vulgaris (PV) with infliximab and prednisone is associated with decreased autoantibodies and increase in immature B cells compared to treatment with prednisone. (Vols. 132). J Invest Dermatol.

Messingham, K., Frydman, A. S., Roewe, R. J. & Fairley, J. A. (2012). FceRI expression by eosinophils in BP and a potential pathogenic role in eosinophil degranulation. (Vols. 132). J Invest Dermatol.

London, V. A., Kim, G. H., Woodley, D. T. & Fairley, J. A. (2012). Successful treatment of bullous pemphigoid with omalizumab. Arch Dermatol, 148(11), 1241-3. PMID: 23165827.

Asarch, A., Swick, B. & Fairley, J. A. (2012). Cryptic esophageal pemphigus vulgaris despite apparent clinical remission. J Am Acad Dermatol, 67(5), e213-4. PMID: 23062919.

Messingham, K., Frydman, A., Roewe, R. J. & Fairley, J. A. (2012). FA role for IgE receptor expression on eosinophils in BP. (Vols. 132). (4), pp. S1-S18. J Invest Derm.

Murrell, D. F., Daniel, B. S., Joly, P., Borradori, L., Amagai, M., Hashimoto, T., Caux, F., Marinovic, B., Sinha, A. A., Hertl, M., Bernard, P., Sirois, D., Cianchini, G., Fairley, J. A., Jonkman, M. F., Pandya, A. G., Rubenstein, D., Zillikens, D., Payne, A. S., Woodley, D., Zambruno, G., Aoki, V., Pincelli, C., Diaz, L., Hall, R. P., Meurer, M., Mascaro Jr, J. M., Schmidt, E., Shimizu, H., Zone, J., Swerlick, R., Mimouni, D., Culton, D., Lipozencic, J., Bince, B., Grando, S. A., Bystryn, J. & Werth, V. P. (2012). Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts. J Am Acad Dermatol, 66(3), 479-85.

Wilson, T. C., Legler, A. A., Madison, K. C., Fairley, J. A. & Swick, B. (2012). Erythema migrans: a spectrum of histopathologic changes. AM J Dermatopath, 34(8), 834-7. PMID: 22722463.

Fairley, J. A. (2012). Cutaneous mineralization and ossification. In L. Goldsmith , S. Katz , B. Gilchrest , A. Paller , D. Leffell , K. Wolff (Eds.) Fitzpatrick's Dermatology in General Medicine, Eighth Edition, 2 Volume set. McGraw Hill, New York, NY.

Messingham, K. N., Pietras, T. A. & Fairley, J. A. (2012). Role of IgE in bullous pemphigoid: a review and rationale for IgE directed therapies. G Ital Dermatol Venereol, 147(3), 251-7. PMID: 22648326.

Messingham, K., Srikantha, R., DeGueme, A. M. & Fairley, J. A. (2011). FcR-independent effects of IgE and IgG autoantibodies in bullous pemphigoid. J Immunol, 187(1), 553-60. PMID: 21646296.

Frydman, A. S., Fairley, J. A. (2011). New and innovative interventions in the management of pemphigus. PMID: 21566551.

Frydman, A. S., Messingham, K. & Fairley, J. A. (2011). Eosinophils express the high affinity IgE receptor(FceRI) in bullous pemphigoid. (Vols. 131). pp. S8 (043A). J Invest Dermatol.

Bassis, A. V., Fairley, J. A., Ameln, R. T. & Swick, B. L. (2011). Cutaneous Rosai-Dorfman disease following pneumococcal vaccination. J Am Acad Dermatol, 65(4), 890-2. PMID: 21920257.

Noe, M. H., Messingham, K. A., Brandt, D. S., Andrews, J. I. & Fairley, J. A. (2010). Pregnant women have increased incidence of IgE autoantibodies reactive with the skin and placental antigen BP180 (type XVII collagen). J Reprod Immunol, 85(2), 198-204.

Messingham, K., Jay, M. & Fairley, J. A. (2010). Signal transduction triggered by IgE class autoantibodies in bullous pemphigoid. (Vols. 110). pp. S19 (109A). J Invest Dermatol.

Messingham, K., Onoh, A. L., Vanderah, E. A., Giudice, G. J. & Fairley, J. A. (2010). An IgE monoclonal antibody to BP180-NC16A replicates the effects of bullous pemphigoid IgE in vitro. (Vols. 110). pp. S9 (049A). J Invest Dermatol.

Swick, B., Srikantha, R. N., Messingham, K. & Fairley, J. A. (2010). Further characterization of C-KIT and PDGFR-alpha mutational status in Merkel cell carcinoma; Implications for treatment with imatinib mesylate. (Vols. 110). pp. S31 (183A). J Invest Dermatol.

Fairley, J. A., Baum, C. L., Brandt, D. S. & Messingham, K. (2009). Pathogenicity of IgE in autoimmunity: successful treatment of bullous pemphigoid with omalizumab. J Allergy Clin Immunol, 123(3), 704-5. PMID: 19152970.

Helmbach, L., Li, N., Huang, W., Giudice, G. J., Fairley, J. A., Marinkovich, P., Diaz, L. & Liu, Z. (2009). Mapping pathogenic epitopes recognized by herpes gestationis autoantibodies using humanized BP180NC16A mice. (Vols. 129). pp. S17 (97A). J Invest Dermatol.

Noe, M. H., Messingham, K., Brandt, D. & Fairley, J. A. (2009). Pregnant women have an increased incidence of IgE-class antibodies directed against BP180. (Vols. 129). pp. S15 (85A). J Invest Dermatol.

Messingham, K., DeGueme, A. & Fairley, J. A. (2009). BP180-specific IgE directly affects keratinocyte structure and function. (Vols. 129). pp. S15 (89A). J invest Dermatol.

Messingham, K., Noe, M. H., Chapman, M. A., Giudice, G. J. & Fairley, J. A. (2009). A novel ELISA reveals high frequencies of BP180-specific IgE production in bullous pemphigoid. J Immunol Methods, 346(1-2), 18-25. PMID: 19422829.

Wong, M. M., Messingham, K., Boddicker, E., Arlian, L., Yancey, K. B. & Fairley, J. A. (2009). The presence of cutaneous autoantibodies in scabies. (Vols. 129). pp. S17 (98A). J Invest Dermatol.

Wong, M. M., Giudice, G. J. & Fairley, J. A. (2009). Autoimmunity in bullous pemphigoid. G Ital Dermatol Venereol, 144(4), 411-21. PMID: 19755944.

Messingham, K., Noe, M. H., Chapman, M., Giudice, G. J. & Fairley, J. A. (2008). Development of an ELISA to detect BP180-specific IgE. (Vols. 128). pp. S24 (143A). J Invest Dermatol.

Noe, M. H., Chen, M., Woodley, D. T. & Fairley, J. A. (2008). Familial epidermolysis bullosa acquisita. Dermatol Online J, 14(12), 2. PMID: 19265615.

Conlon, J. D., Dauenhauer, M. D., Tonkovic-Capin, V., Talano, J., Margolis, D., Drolet, B. A. & Fairley, J. A. (2008). Voriconazole-induced blistering in the setting of graft versus host disease: A report of 2 patients. J Am Acad Dermatol, 58(3), 848-7. PMID: 18280346.

Lazarova, Z., Salato, V. K., Landschuetzer, C. M., Janson, M., Fairley, J. A. & Yancey, K. B. (2008). IgG anti-laminin-332 autoantibodies are present in a subset of patients with mucous membrane, but not bullous, pemphigoid. J Am Acad Dermatol, 58(6), 951-8. PMID: 18396347.

Liu, Z., Sui, W., Zhao, M., Li, Z., Li, N., Thresher, R., Giudice, G. J., Fairley, J. A., Sitaru, C., Zillikens, D., Ning, G., Marinkovich, M. P. & Diaz, L. A. (2008). Subepidermal blistering induced by human autoantibodies to BP180 requires innate immune players in a humanized bullous pemphigoid mouse mod. J Autoimmun, 31(4), 331-8. PMID: 18922680.

Robbins, A., Lazarova, Z., Jansen, M. M. & Fairley, J. A. (2007). Pemphigus vulgaris presenting in a radiation portal. J Am Acad Dermatol, 56(5 Supple), S82-5. PMID: 17434046.

Chapman, M. A., Olague-Marchan, M., Yancey, K. B., Giudice, G. J. & Fairley, J. A. (2007). IgE class autoantibodies against BP180 in herpes gestationis and cicatricial pemphigoid. (Vols. 127). pp. S15 (90A). J Invest Dermatol.

Liu, Z., Leighty, L., Zhao, M., Li, N., Fu, C. L., Giudice, G. J., Fairley, J. A., Sitaru, C. & Zillikens, D. (2007). Identification of BP180 pathogenic epitope using humanized BP 180 NC16A mice. (Vols. 127). pp. S12 (70A). J Invest Dermatol.

DeGueme, A., Giudice, G. J., Fu, C. L. & Fairley, J. A. (2007). Bullous pemphigoid IgE stimulates IL-8 production by keratinocytes. (Vols. 127). pp. S17 (99A). J Invest Dermatol.

Fairley, J. A., Burnett, C. T., Fu, C., Larson, D. L., Fleming, M. G. & Giudice, G. J. (2007). A pathogenic role for IgE in autoimmunity: bullous pemphigoid IgE reproduces the early phase of lesion development in human skin grafted to nu/nu mice. J Invest Dermatol, 127(11), 2605-11. PMID: 17611576.

Salato, V. K., Lazarova, Z., Janson, M., Fairley, J. A. & Yancey, K. B. (2006). Bullous pemphigoid patients do not possess IgG autoantibodies reactive with lamnin 5. (Vols. 126). pp. 8A (47A). J Invest Dermatol.

Salato, V. K., Lopez, A., Lazarova, Z., Fairley, J. A. & Lin, M. S. (2005). Monoclonal murine anti-idiotypic IgG blocks the development of experimental pemphigus vulgari. (Vols. 124). pp. A6 (031A). J Invest Dermatol.

Burnett, C. T., Fu, C. L., Janson, M. M., Larson, D., Giudice, G. J. & Fairley, J. A. (2005). Development of a model for testing the pathogenicity of BP IgE autoantibodies. (Vols. 124). pp. A11 (061A). J Invest Dermatol.

Salato, V., Hacker-Foegen, M. K., Lazarova, Z., Fairley, J. A. & Lin, M. S. (2005). Role of intramolecular epitope spreading in pemphigus vulgaris. Clin Immunol, 116(1), 54-64.

Fairley, J. A., Fu, C. & Giudice, G. J. (2005). Mapping the binding sites of anti-BP180 immunoglobulin E autoantibodies in bullous pemphigoid. J Invest Dermatol, 125, 467-472.

Fairley, J. A., Burnett, C. T., Fu, C. L., Fleming, M. G. & Giudice, G. J. (2005). Injection of bullous pemphigoid (BP) IgE autoantibodies into human skin grafted to nu/nu mice replicates the urticarial stage of BP. (Vols. 124). pp. A13 (073A). J Invest Dermatol.

Salato, V. K., Foegen, M. K., Lazarova, Z., Fairley, J. A. & Lin, M. S. (2004). The role of intra-molecular epitope spreading in pemphigus vulgaris. (Vols. 122). (3), pp. A6 (031). J Invest Dermatol.

Reed, K. D., Melski, J. W., Graham, M. B., Regnery, R. L., Sotir, M. J., Wegner, M. V., Kazmierczak, J. J., Stratman, E. J., Fairley, J. A., Li, Y., Swain, G. R., Olson, V. A., Sargent, E. K., Kehl, S. C., Frace, M. A., Kline, R., Foldy, S. L., Davis, J. P. & Damon, I. K. (2004). The detection of monkeypox in humans in the Western Hemisphere. N Engl J Med, 350(4), 342-50. PMID: 14736926.

Colbert, R. L., Allen, D. M. & Fairley, J. A. (2004). Mortality rate of bullous pemphigoid in a US medical center. J Invest Dermatol, 122(5), 1091-5. PMID: 15140208.

Fairley, J. A., Woodley, D. T., Chen, M., Giudice, G. J. & Lin, M. S. (2004). A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading. J Am Acad Dermatol, 51(1), 118-22. PMID: 15243536.

Hacker-Foegen, M. K., Salato, V. K., Olasz, E. B., Fairley, J. A. & Lazarova, Z. (2004). Analysis of autoimmune T cell repertoire in an active pemphigus vulgaris animal model. (Vols. 124). pp. A6 (032A). J Invest Dermatol.

Hacker-Foegen, M. K., Janson, M., Amagai, M., Fairley, J. A. & Lin, M. S. (2003). Pathogenicity and epitope characteristics of anti-desmoglein-1 from pemphigus foliaceus patients expressing only IgG1 autoantibodies. J Invest Dermatol, 121(6), 1373-6. PMID: 14675185.

Woodley, D. T., Krueger, G. G., Jorgensen, C. M., Fairley, J. A., Atha, T., Huang, Y., Chan, L., Keene, D. R. & Chen, M. (2003). Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone. J Invest Dermatol, 121(5), 1021-8. PMID: 14708601.

Hacker, M. K., Fairley, J. A. & Lin, M. S. (2003). T cell receptor gene usage in desmoglein-3 specific T-lymphocytes from patients with pemphigus vulgaris. (Vols. 121). (1), pp. 0852A. J Invest Dermatol.

Hacker-Foegen, M. K., Fairley, J. A. & Lin, M. S. (2003). T cell receptor gene usage in desmoglein-3-specific T lymphocytes from patients with pemphigus vulgaris. J Invest Dermatol, 121(6), 1365-72. PMID: 14675184.

Gunkel, J., Graham, M. B. & Fairley, J. A. (2003). Monkeypox. pp. 1-13. EMedicine.

Hacker, M. K., Janson, M., Fairley, J. A. & Lin, M. S. (2003). Epitopes and pathogenic activity of anti-desmoglein-1 in a subset of pemphigus foliaceus patients expressing only IgG1 autoantibodies. (Vols. 121). (1), pp. 0040A. J Invest Dermatol.

Hacker, M. K., Olasz, E. B., Fairley, J. A., Yancey, K. B. & Lin, M. S. (2003). Anti-idiotypic IgG blocks the reactivity and pathogenicity of anti-desmoglein-3 autoantibodies from patients with pemphigus vulgaris. (Vols. 121). (1), pp. 0080A. J Invest Dermatol.

Dimson, O. G., Giudice, G. J., Fu, C. L., Van den Bergh, F., Warren, S. J., Janson, M. M. & Fairley, J. A. (2003). Identification of a potential effector function for IgE autoantibodies in the organ-specific autoimmune disease bullous pemphigoid. J Invest Dermatol, 120(5), 784-8. PMID: 12713582.

Fu, C. L., Giudice, G. J. & Fairley, J. A. (2003). Bullous pemphigoid IgE and IgG react with BP180 outside of the immunodominant NC16A domain. (Vols. 121). (1), pp. 0094A. J Invest Dermatol.

Fairley, J. A. (2003). Calcifying and ossifying disorders. In Mosby Elsevier (Eds.) Dermatology, 2 Volume set. (8th), pp. 691-726. Jean L. Bolognia, Joseph L. Jorizzo, Ronald P. Rapini, Thomas D Horn, Anthony J. Mancini, Jose M. Mascaro, Stuart J. Salasche, Jean-Hilaire Saurat, Georg Stingl.

Miller, J. J., Giudice, G. J., Janson, M. M. & Fairley, J. A. (2003). Fiberoptic confocal imaging of the skin. (Vols. 1). (0094A) J Invest Dermatol.

Melski, M. J., Reed, K., Stratman, E., Graham, M. B., Fairley, J. A., Edmiston, C., Kehl, S., Foldy, S. R., Swain, G. R., Bierdrzcki, P., Gieryn, D., Ernst, K., Schier, D., Tomasello, C., Rausch, D., Healy-Haney, N., Kreuser, N., Wegner, M. V., Kazmierczak, J. J., Williams, C., Croft, D. R., Bostrom, J. P., Davis, J. P., Ehlenfeldt, R., Kirk, C., Teclaw, R., Messersmith, H., Sotir, M. J., Huhn, G. & Fleischauer, A. T. (2003). Multistate outbreak of monkeypox--Illinois, Indiana, and Wisconsin, 2003. (Vols. 13). (52(23)), pp. 537-40. MMWR Morb Mortal Wkly Rep. PMID: 12803191.

Galbraith, S. S., Fairley, J. A. & Esterly, N. B. (2002). White papules in a child with Down syndrome. Ped Dermatol, 19(3), 271-3. PMID: 12047651.

Lin, M. S., Fu, C. L., Olague-Marchan, M., Hacker, M. K., Zillikens, D., Giudice, G. J. & Fairley, J. A. (2002). Autoimmune responses in patients with linear IgA bullous dermatosis: Both autoantibodies and T lymphocytes recognize the NC16A domain of the BP180 molecule. Clin Immunol, 102(3), 310-9. PMID: 11890718.

Lyon, V. B., Fairley, J. A. (2002). Anticonvulsant-induced pellagra. J Am Acad Dermatol, 46(4), 597-9. PMID: 11907516.

Chen, M., O'Toole, E. A., Sanghavi, J., Mahmud, N., Kelleher, D., Weir, D., Fairley, J. A. & Woodley, D. T. (2002). The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with Crohn's disease have autoantibodies to type VII collagen. J Invest Dermatol, 118(6), 1059-64. PMID: 12060403.

Hacker, M. K., Janson, M., Fairley, J. A. & Lin, M. S. (2002). Isotypes and antigenic profiles of pemphigus foliaceus and pemphigus vulgaris autoantibodies. (Vols. 119). pp. 538A. J Invest Dermatol.

Chen, R., Fairley, J. A., Zhao, M. L., Giudice, G. J., Zillikens, D., Diaz, L. A. & Liu, Z. (2002). Macrophages, but not T and B lymphocytes are critical for subepidermal blister formation in experimental bullous pemphigoid: macrophage-mediated neutrophil infiltration depends on mast cell activation. J Immunol, 169(7), 3987-92. PMID: 12244200.

Fairley, J. A., Dimson, I. G., Fu, C. L., Janson, M. M. & Giudice, G. J. (2002). BP180 specific IgE in bullous pemphigoid. (Vols. 119). pp. 607A. J Invest Dermatol.

Suchniak, J. M., Diaz, L. A., Lin, M. S. & Fairley, J. A. (2002). IgM mediated epidermolysis bullosa acquisita. Arch Derm, 138(10), 1385-6. PMID: 12374560.

Hacker, M. K., Janson, M., Fairley, J. A. & Lin, M. S. (2002). Isotypes and antigenic profiles of pemphigus foliaceus and pemphigus vulgaris autoantibodies. Clin Immunology, 105(1), 64-74. PMID: 12483995.

Fairley, J. A., Zivony, D. (2001). Epidermal kinetics and regulation of cell proliferation. In R. K. Freinkel , D. T. Woodley (Eds.) The Biology of the Skin. pp. 201-207. The Parthenon Press Group Inc.

Dimson, O., Fu, C., Janson, M., Giudice, G. J. & Fairley, J. A. (2001). Detection of BP180 specific IgE antibodies in bullous pemphigoid and identification of a potential effector function. (Vols. 117). pp. 461A. J Invest Dermatol.

Woodley, D. T., Chen, M., Krueger, K., Jorgensen, C., Chan, L. & Fairley, J. A. (2001). Dermal fibroblasts alone are capable of producing type VII (anchoring fibril) collagen at the dermal-epidermal junction. (Vols. 119). pp. 399A. J Invest Dermatol.

Beaird, L. M., Kahloon, N., Franco, J. & Fairley, J. A. (2001). Incidence of hepatitis C with lichen planus. J Am Acad Dermatol, 44(2), 311-2. PMID: 11174399.

Liu, Z., Shapiro, S. D., Zhou, X., twining, S. S., Senior, R. M., Giudice, G. J., Fairley, J. A. & Diaz, L. A. (2000). A critical role for neutrophil elastase in experimental bullous pemphigoid. J Clin Invest, 105(1), 113-23. PMID: 10619867.

Gharia, M. J., Fairley, J. A., Lin, M. s., Liu, Z., Giudice, G. J. & Diaz, L. A. (2000). Autoimmune diseases of the skin. In R. G. Lahita , W. H. Reeves , N. Chiorazzi (Eds.) Textbook of Autoimmune Diseases. (1st), pp. 409-427. Lippincott Williams & Wilkins.

Liu, Z., Zhou, X., Ding, X., Chen, R., Shapiro, S. D., Senior, R. M., Giudice, G. J., Fairley, J. A. & Diaz, L. A. (1999). The role of neutrophil elastase, gelatinase B and plasmin/plasminogen activators in pemphigus foliaceus and pemphigus vulgaris in mice. (Vols. 112). pp. 562. J Invest Dermatol.

Ding, X., Diaz, L. A., Fairley, J. A., Giudice, G. J. & Liu, Z. (1999). The anti-desmoglein 1 autoantibodies in pemphigus vulgaris sera are pathogenic. J Invest Dermatol, 112(5), 739-43. PMID: 10233765.

Fairley, J. A., Suchniak, J. & Paller, A. S. (1999). Hedgehog hives. Arch Derm, 135(5), 561-3. PMID: 10328197.

Warren, K. J., Fairley, J. A. (1998). Pain and swelling along the nail fold of a 51-year-old man. (Vols. 4). (1), pp. 1. Dermatol Online J. PMID: 10217741.

Fairley, J. A., Ding, X., Giudice, G. J. & Diaz, L. A. (1998). Pemphigus foliaceus and pemphigus vulgaris. In L. Jameson (Eds.) Textbook of Molecular Medicine. pp. 811-16. Humana Press, Totowa, NJ.

Warren, K. J., Fairley, J. A. (1998). Stump the experts. Subungual exostosis. Dermatol Surg, 24(2), 287-9. PMID: 9491127.

Pomeranz, A. J., Fairley, J. A. (1998). Systematic evaluation of the skin of children. Ped Clin North Am, 45(1), 49-63. PMID: 9491086.

Chan, L. S., Vanderlugt, C. J., Hashimoto, T., Nishikawa, T., Zone, J. J., Black, M. M., Wojnarowska, F., Stevens, S. R., Chen, M., Fairley, J. A., Woodley, D. T., Miller, S. D. & Gordon, K. B. (1998). Epitope spreading: lessons from autoimmune skin diseases. J Invest Dermatol, 110(2), 103-9. PMID: 9457902.

McCord, M., Fairley, J. A. (1998). Dermatology. In K. Kutty , J. Sebastian , D. Berg , B. Mewls , K. Mohenor (Eds.) Kochars Concise Textbook of Medicine. Willliam and Wilkins, New York, NY.

Fairley, J. A., Pomeranz, A. J. (1998). A bullous pemphigoid-like skin eruption following a chemical burn. J Am Acad Derm, 38(2 PT2), 337-40. PMID: 9486711.

Lin, M. S., Swartz, S. J., Gharia, M., Fairley, J. A. & Diaz, L. A. (1998). Autoimmune responses of linear IgA disease: both T cells and autoantibodies recognize NC16a domain of BP180. (Vols. 110). pp. 482. J Invest Dermatol.

Baselga, E., Fairley, J. A. (1998). Calcifying and ossifying disorders in children. In Textbook of Paediatric Dermatology. Oxford University Press, London.

Gharia, M. J., Swartz, S. J., Giudice, G. J., Fairley, J. A., Diaz, L. A. & Lin, M. S. (1998). T cells from a mother with herpes gestationis, but not the newborn, specifically respond to BP180. (Vols. 110). pp. 507. J Invest Dermatol.

Ding, X., Diaz, L. A., Fairley, J. A., Giudice, G. J. & Liu, Z. (1998). The anti-desmoglein autoantibodies in PV sera are pathogenic. (Vols. 110). pp. 507. J Invest Dermatol.

Mascaro Jr, J. M., Espana, A., Liu, Z., Ding, X., Swartz, S. J., Fairley, J. A. & Diaz, L. A. (1997). Mechanisms of acantholysis in pemphigus vulgaris: Role of IgG valence. J Immunol Immunopath, 85(1), 90-6. PMID: 9325074.

Ding, X., Aoki, V., Mascaro, J. M., Lopez-Swiderski, A., Diaz, L. A. & Fairley, J. A. (1997). Mucosal and mucocutaneous (generalized) pemphigus vulgaris show distinct autoantibody profiles. J Invest Dermatol, 109(4), 592-6. PMID: 9326396.

Wang, J., Kwon, J., Ding, X., Fairley, J. A., Woodley, D. T. & Chan, L. S. (1997). Nonsecretory IgA1 autoantibodies targeting a desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis. Am J Path, 150(6), 1901-7. PMID: 9176383.

Espana, A., Diaz, L. A., Mascaro Jr, J. M., Giudice, G. J., Fairley, J. A., Till, G. O. & Liu, Z. (1997). Mechanisms of acantholysis in pemphigus foliaceus. Clin Immunol Immunopath, 85(1), 83-9. PMID: 9325074.

Miller, E. S., Fairley, J. A. & Neuburg, M. (1997). Vulvar basal cell carcinoma. Dermatol Surg, 23(3), 207-9. PMID: 9145965.

Lin, M. S., Swartz, S. J., Lopez, A., Ding, X., Fairley, J. A. & Diaz, L. A. (1997). T lymphocytes from a subset of patients with pemphigus vulgaris respond to both desmoglein-3 and desmoglein-1. J Invest Dermatol, 109(6), 734-7. PMID: 9406813.

Liu, Z., Twining, S., Giudice, G. J., Zhou, X., Fairley, J. A. & Diaz, L. A. (1997). Neutrophil elastase is essential for subepidermal blistering in experimental bullous pemphigoid. (Vols. 108). pp. 556A. J Invest Dermatol.

Lin, M. S., Swartz, S. J., Lopez, A., Ding, X., Fairley, J. A. & Diaz, L. A. (1997). Characterization of desmoglein-1 epitopes recognized by T cells from patients with fogo selvagem. (Vols. 108). pp. 544A. J Invest Dermatol.

Caux, F. A., Giudice, G. J., Diaz, L. A. & Fairley, J. A. (1997). Autoimmune subepithelial blistering diseases with ocular involvement. Immunol Allergy Clin, 17(1), 139-59.

Liu, Z., Giudice, G. J., Zhou, X., Fairley, J. A. & Diaz, L. A. (1997). Interleukin-1 and-6 are required for subepidermal blistering in experimental bullous pemphigoid. (Vols. 108). pp. 538A. J Invest Dermatol.

Liu, Z., Giudice, G. J., Zhou, X., Swartz, S. J., Troy, J. L., Fairley, J. A., Till, G. O. & Diaz, L. A. (1997). A major role for neutrophils in experimental bullous pemphigoid. J Invest Dermatol, 100(5), 1256-63. PMID: 9276744.

Lin, M. S., Swartz, S. J., Lopez, A., Ding, X., Fernandez-Vina, M. A., Fairley, J. A. & Diaz, L. A. (1997). Development and characterization of desmoglein-3 specific T cells from patients with pemphigus vulgaris. J Clin Invest, 99(1), 31-40. PMID: 9011573.

Wang, J., Kwon, J., Ding, X., Fairley, J. A., Woodley, D. T. & Diaz, L. A. (1997). IgA pemphigus is mediated by a non-secretory IgA1 autoantibody targeting desmoglein 3. (Vols. 108). pp. 638A. J Invest Dermatol.

Lin, M. S., Swartz, S. J., Lopez, A., Ding, X., Fairley, J. A. & Diaz, L. A. (1997). Development of Dsg-1 specific long term B cell lines from patients with pemphigus foliaceus. (Vols. 108). pp. 560A. J Invest Dermatol.

Ding, X., Mascaro Jr, J. M., Goldberg, E., Fleming, M. G., Diaz, L. A. & Fairley, J. A. (1996). IgG from a subset of PV patients with oral disease is not pathogenic in neonatal BALB/c mice. (Vols. 106). pp. 850A. J Invest Dermatol.

Kwon, J., Wang, J., Ding, X., Fairley, J. A., Woodley, D. T. & Chan, L. S. (1996). IgA pemphigus vulgaris is mediated by a non-secretory IgA1 autoantibody targeting desmoglein 3. (Vols. 44). pp. 402A. J Invest Med.

Miller, E. S., Esterly, N. B. & Fairley, J. A. (1996). Progressive osseous heteroplasia. Arch Dermatol, 132(7), 787-91. PMID: 8678571.

Mascaro Jr, J. M., Espana-Alonso, A., Liu, Z., Swartz, S., Fleming, M. G., Giudice, G. J., Fairley, J. A. & Diaz, L. A. (1996). Monovalent Fab fragments from pemphigus vulgaris IgG are pathogenic in neonatal BALB/c mouse model. (Vols. 106). pp. 812A. J Invest Dermatol.

Liu, Z., Twinning, S. S., Giudice, G. J., Zhou, X., Fairley, J. A., Troy, J. L. & Diaz, L. A. (1996). Elastase plays a direct role in blister formation in experimental bullous pemphigoid. (Vols. 10). pp. A1407. FASB J.

Fairley, J. A. (1996). The role of adhesion molecules in autoimmune blistering diseases. In M. V. Dahl (Eds.) Current Opinion in Dermatology. pp. 27-32. Rapid Science Publishers.

Diaz, L. A., Espana-Alonso, A., Fairley, J. A., Giudice, G. J., Mascaro Jr, J. M. & Liu, Z. (1996). Skin diseases autoantibodies. In J. B. Peter , Y. Schoenfeld (Eds.) Autoantibodies. (1), pp. 746-765. Elsevier Science B.V., The Netherlands.

Liu, Z., Twining, S., Giudice, G. J., Zhou, X., Fairley, J. A., Troy, J. L. & Diaz, L. A. (1996). Bullous pemphigoid mouse model: neutrophil elastase plays a major role in subepidermal blister formation. (Vols. 44). pp. 402A. J Invest Med.

Lin, M. S., Lopez, A., Fairley, J. A. & Diaz, L. A. (1996). Development and characterization of T cell lines responding to desmoglein-3. (Vols. 106). pp. 832A. J Invest Dermatol.

Liu, Z., Giudice, G. J., Swartz, S. J., Zillikens, D., Troy, J. L., Fairley, J. A. & Diaz, L. A. (1996). Bullous pemphigoid mouse model: dermal-epidermal separation induced by anti-BP180 antibodies is dependent on neutrophil Fc receptor activity. (Vols. 106). pp. 801A. J Invest Dermatol.

Mascaro Jr, J. M., Fairley, J. A., Giudice, G. J. & Diaz, L. A. (1996). Autoantibodies in paraneoplastic pemphigus. In Y. Schoenfeld (Eds.) Autoantibodies. (1) Elsevier, The Netherlands.

Walsh, J. S., Fairley, J. A. (1996). Calciphylaxis. J Amer Acad Dermatol, 35(5), 786-7. PMID: 8912583.

Lin, M. S., Swartz, S. J., Lopez, A., Fairley, J. A. & Diaz, L. A. (1996). Development and characterization of desmoglein-3 specific T-lymphocytes. (Vols. 10). pp. A1305. FASEB J.

Fairley, J. A. (1996). Cicatricial pemphigoid. J Geria Dermatol, 4, 42-46.

Liu, Z., Diaz, L. A., Swartz, S. J., Fairley, J. A. & Giudice, G. J. (1995). Molecular mapping of a BP180 peptide that can block subepidermal blistering in experimental bullous pemphigoid. (Vols. 104). pp. 559. J Invest Dermatol.

Espana, A., Diaz, L. A., Giudice, G. J., Fairley, J. A., Till, G. O. & Liu, Z. (1995). The role of complement in experimental pemphigus foliaceus. (Vols. 105). pp. 872A. J Invest Dermatol.

Hansen, K. K., Troy, J. L. & Fairley, J. A. (1995). Multiple papules of the scalp and forehead. Steatocystoma multiplex (facial papular variant). Arch Dermatol, 131(7), 835. PMID: 7611805.

Muramatsu, T., Putzer, K. P., Diaz, L. A., Giudice, G. J. & Fairley, J. A. (1995). Identification of a conserved calcium binding site on the intracellular domain of cadherins. (Vols. 104). pp. 557. J Invest Dermatol.

Liuz, Z., Giudice, G. J., Swartz, S. J., Fairley, J. A., Till, G. O., Troy, J. L. & Diaz, L. A. (1995). The role of complement in experimental bullous pemphigoid. J Clin Invest, 95(4), 1539-44. PMID: 7706459.

Liuz, Z., Diaz, L. A., Swartz, S. J., Troy, J. L., Fairley, J. A. & Giudice, G. J. (1995). Molecular mapping of a pathogenically relevant BP180 epitope associated with experimentally induced murine bullous pemphigoid. J Immunol, 155(11), 5449-54. PMID: 7594563.

Liu, Z., Diaz, L. A., Swartz, S. J., Zillikens, D., Troy, J. L., Fairley, J. A. & Giudice, G. J. (1995). Bullous pemphigoid mouse model: dissection of the inflammatory response. (Vols. 104). pp. 558. J invest Dermatol.

Hans-Filho, G., dos Santos, V., Katayama, J. H., Aoki, V., Rivitti, E. A., Sampaio, S. A., Friedman, H., Moraes, J. R., Moraes, M. E., Eaton, D. P., Lopez, A. L., Hoffman, R. G., Fairley, J. A., Giudice, G. J. & Diaz, L. A. (1995). An active focus of high prevalence of fogo selvagem on a Amerindian reservation in Brazil. J Invest Dermatol, 107(1), 68-75. PMID: 8762842.

Ding, X., Aoki, V., Fleming, M. G., Diaz, L. A. & Fairley, J. A. (1995). Heterogeneity of pemphigus vulgaris autoantibodies. (Vols. 105). pp. 872A. J Invest Dermatol.

Emery, D. J., Diaz, L. A., Fairley, J. A., Lopez, A., Taylor, A. F. & Giudice, G. J. (1995). Pemphigus foliaceus and pemphigus vulgaris autoantibodies react with the extracellular domain of desmoglein-1. J Invest Dermatol, 104(3), 323-8. PMID: 7860995.

Walsh, J. S., Fairley, J. A. (1995). Calcifying disorders of the skin. J Amer Acad Derm, 33(5 Pt 1), 693-706 quiz 707-10. PMID: 7593766.

Fairley, J. A., Heintz, P. W., Neuburg, M., Diaz, L. A. & Giudice, G. J. (1995). Expression pattern of the bullous pemphigoid-180 antigen in normal and neoplastic epithelia. Br J Dermatol, 133(3), 385-91. PMID: 8546992.

Troy, J. L., Liu, Z., Fairley, J. A., Diaz, L. A. & Giudice, G. J. (1995). Dissection of the skins inflammatory response in experimentally induced pemphigoid. (Vols. 22). pp. 93A. J Cutan Pathol.

Pomeranz, A. J., Fairley, J. A. (1994). Management errors leading to unnecessary hospitalization for kerion. Pediatrics, 93(6 Pt 1), 986-8. PMID: 8190588.

Muramatsu, T., Putzer, K. P., Diaz, L. A., Giudice, G. J. & Fairley, J. A. (1994). Mapping the extra- and intracellular calcium binding sites on the pemphigus vulgaris antigen (desmoglein 3). (Vols. 102). pp. 563A. J Invest Dermatol.

Aoki, V., Diaz, L. A., Taylor, A. F., Witman, P. M. & Fairley, J. A. (1994). Immunological specificity of pemphigus vulgaris autoantibodies. (Vols. 102). pp. 564A. J Invest Dermatol.

Giudice, G. J., Wilske, K. C., Anhalt, G. J., Fairley, J. A., Taylor, A. F., Emery, D. J., Hoffman, R. G. & Diaz, L. A. (1994). Development of an ELISA to detect anti-BP180 autoantibodies in the sera of bullous pemphigoid and herpes gestationis patients. J Invest Dermatol, 102(6), 878-81. PMID: 7516396.

Scott, G. A., Fairley, J. A., Liang, H. & Giudice, G. J. (1994). Human melanocytes express the BP180 antigen in vitro. (Vols. 102). pp. 551A. J Invest Dermatol.

Liu, Z., Diaz, L. A., Schwartz, S. J., Troy, J. L., Taylor, A. F., Emery, D. J., Fairley, J. A. & Giudice, G. J. (1994). Bullous pemphigoid mouse model: a time course study of the inflammatory response during subepidermal blister formation. (Vols. 42). pp. 429A. Clin Res.

Liu, Z., Diaz, L. A., Swartz, S. J., Taylor, A. F., Emery, D. J., Troy, J. L., Fairley, J. A. & Giudice, G. J. (1994). Defining the animal model of bullous pemphigoid and herpes gestationis by passive transfer of anti-BP180 antibodies. (Vols. 102). pp. 558A. J Invest Dermatol.

Aoki, V., Diaz, L. A., Taylor, A. F. & Fairley, J. A. (1993). Pemphigus vulgaris autoantibodies: IgG subclass analysis utilizing immunofluorescence and immunoblotting. (Vols. 41). pp. 663A. Clin Res.

Liu, Z., Diaz, L. A., Taylor, A. F., Emery, D. J., Giudice, G. J. & Fairley, J. A. (1993). Studies on the human and murine bullous pemphigoid 180 (BP180) antigen. pp. 663A. Clin Res.

Fairley, J. A. (1993). Tretinoin (retinoic acid) revisited. N Engl J Med, 20(328(20)), 1486-7. PMID: 8479470.

Mansilla-Orihuela, C. S., Diaz, L. A., Taylor, A. F., Emery, D. J., Fairley, J. A. & Giudice, G. J. (1993). Bullous pemphigoid autoantibodies directed against a dominant epitope of the BP180 ectodomain are predominantly of the IgG2 subclass. pp. 663A. Clin Res.

Muramatsu, T., Putzer, K. P., Diaz, L. A., Giudice, G. J. & Fairley, J. A. (1993). Identification of calcium binding sites on the pemphigus vulgaris antigen by 45calcium over. pp. 663A. Clin Res.

Giudice, G. J., Emery, D. J., Liu, Z., Fairley, J. A. & Diaz, L. A. (1993). A bullous pemphigoid and herpes gestationis reactive site on the ectodomain of the human BP180 autoantigen is not present on the murine BP180 homologue. (Vols. 41). pp. 409A. Clin Res.

Liu, Z., Diaz, L. A., Troy, J. L., Taylor, A. F., Emery, D. J., Fairley, J. A. & Giudice, G. J. (1993). A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180. J Clin Invest, 92(5), 2480-88. PMID: 7693763.

Hertz, P. W., Giudice, G. J., Diaz, L. A. & Fairley, J. A. (1993). Distribution of the bullous pemphigoid-180 autoantigen in normal and transformed tissue. (Vols. 41). pp. 410A. Clin Res.

Fairley, J. A., Putzer, K. P. & Giudice, G. J. (1992). Keratinocyte proliferation: correlation with calmodulin gene expression. (Vols. 98). pp. 640. J Invest Dermatol.

Fairley, J. A., Arrindell, S. J. (1992). Calcium regulation of epidermal cell physiology. In A. Ohkawara , J. McGuiere (Eds.) The Biology of the Epidermis, Symposium Proceedings 5th Japan-US Joint Seminar. pp. 67-75. Elsevier Inc.

Fairley, J. A., Putzer, K. P., Emery, D. J. & Giudice, G. J. (1991). Expression of calmodulin genes by keratinocytes in vitro and in vivo. (Vols. 39). pp. 458A. Clin Res.

Fairley, J. A., Scott, K. D., Jensen, K. D., Goldsmith, L. A. & Diaz, L. A. (1991). Characterization of keratocalmin, a calmodulin-binding protein from human epidermis. J Clin Invest, 88(1), 315-22. PMID: 1711543.

Fairley, J. A. (1991). Calcium metabolism and the pathogenesis of dermatologic disease. Semin Dermatol, 10(3), 225-31. PMID: 1657105.

Fairley, J. A., Putzer, K. P. & Giudice, G. J. (1991). Calmodulin gene expression in vivo and in vitro. (Vols. 39). pp. 719A. Clin Res.

Scheinman, P. L., Helm, K. F. & Fairley, J. A. (1991). Acral necrosis in a patient with chronic renal failure. Arch Dermatol, 127(2), 248-9. PMID: 1990994.

Fairley, J. A. (1991). Calcium: A second messenger. In Biochemistry and Physiology of the Skin. Oxford University Press, New York, NY.

Fairley, J. A. (1990). Intracellular receptors for cyclosporine A. J Amer Acad Dermatol, 23(6 Pt 2), 1329-32. PMID: 2277142.

Fairley, J. A., Scott, G. A., Jensen, K., Goldsmith, L. A. & Diaz, L. A. (1990). Identification of a human desmosome calmodulin-binding protein. (Vols. 38). pp. 610A. Clin Res.

Fairley, J. A., Fung, P. J. & Ewing, N. M. (1990). Effect of ciclosporin A on epidermal keratinocytes in vitro: lack of a direct effect on calmodulin. Skin Pharmacol, 3(3), 149-56. PMID: 2078349.

Fairley, J. A., Ghaneian, M. R. & Diaz, L. A. (1990). Identification and characterization of keratocalmin in keratinocytes in vitro. (Vols. 38). pp. 858A. Clin Res.

Milstone, L., Fairley, J. A., Insogna, K., Stewart, A. & Reuveni, H. (1989). Parathyroid hormone-like peptides increase intracellular calcium and differentiation of keratinocytes. (Vols. 107). pp. 73A. J Cell Biol.

Milstone, L., Fairley, J. A., Insogna, K., Stewart, A., Reuveni, H. & Schwartz, P. (1989). Parathyroid hormone-like peptides increase intracellular calcium and differentiation of keratinocytes. (Vols. 37). pp. 637A. Clin Res.

Fairley, J. A., Fung, P. F. & Ewing, N. M. (1989). Calmodulin content of keratinocytes in vitro, effect of proliferation and cyclosporin A. (Vols. 37). pp. 633A. Clin Res.

Fairley, J. A. (1989). A Second Messenger. In J. P. Callen , M. V. Dahl , L. E. Golitz , L. A. Schachner , S. J. Stegman (Eds.) Advances in Dermatology. pp. 95-112. Year Book Medical Publishers, Inc.

Fairley, J. A. (1989). Calcium and the skin. Arch Dermatol, 124(3), 443-4. PMID: 3345095.

Fairley, J. A., Ewing, N. M. & Keng, P. C. (1988). Extracellular calcium-induced terminal differentiation of keratinocytes is accompanied by an increase in free intracellular calcium. (Vols. 36). pp. 643A. Clin Res.

Fairley, J. A., Sawyer, J. R. & Ewing, N. M. (1988). Characterization of epidermal calmodulin-binding proteins. (Vols. 36). pp. 375A. Clin Res.

Silverman, A. K., Fairley, J. A. & Wong, R. C. (1988). Cutaneous and immunologic reactions to phenytoin. J Amer Acad Dermatol, 18(4), 721-41.

Fairley, J. A., Ewing, N. M. & Keng, P. C. (1987). Retinoic acid decreases the free intracellular calcium level of keratinocytes. (Vols. 88). (4), pp. 488. Clin Res (J Invest Dermatol).

Fairley, J. A., Ewing, N. & Keng, P. (1986). Retinoic acid decreases the free intracellular calcium level of keratinocytes. (Vols. 34). pp. 885A. Clin Res.

Fairley, J. A., Keng, P. (1986). Detection of changes in free intracellular Ca++ in keratinocytes using Indo-1 AM and flow cytometry. (Vols. 34). pp. 748A. Clin Res.

Negi, M., Lane, A. T., McCoon, P. E., Fairley, J. A. & Goldsmith, L. A. (1986). Monoclonal antibody to a 35 kD epidermal protein induces cell detachment. J Invest Dermatol, 86(6), 634-7. PMID: 3519785.

Fairley, J. A., Duell, E. A., Hogan, V. A. & Marcelo, C. L. (1985). Production of arachidonic acid metabolites by low calcium regulated keratinocytes. (Vols. 84). (365A) J Invest Dermatol.

Fairley, J. A., Weiss, J. & Marcello, C. L. (1985). Increased prostaglandin synthesis by low calcium regulated keratinocytes. J Invest Dermatol, 86(3), 195-8. PMID: 2579165.

Woo, T. Y., Solomon, A. R. & Fairley, J. A. (1985). Pemphigus vegetans limited to the oral mucosa. Arch Dermatol, 121(2), 271-2. PMID: 3977347.

Soong, H. K., Fairley, J. A. (1985). Actin in human corneal epithelium. Association for Research in Vision and Ophthalmology.

Fairley, J. A., Marcelo, C. L., Hogan, V. A. & Voorhees, J. J. (1985). Increased calmodulin levels in psoriasis and low Ca++ regulated mouse epidermal keratinocyte cultures. J Invest Dermatol, 84(3), 195-98. PMID: 2579165.

Soong, H. K., Fairley, J. A. (1985). Actin in human corneal epithelium. Arch Ophthalmol, 103(4), 565-8. PMID: 3985841.

Fairley, J. A., Pentland, A. P. & Voorhees, J. J. (1984). Urticaria pigmentosa responsive to nifedipine. J Amer Acad Dermatol, 11(4 Pt 2), 740-3. PMID: 6491000.

Madison, K. C., Fairley, J. A., Marcelo, C. L. & Voorhees, J. J. (1984). Prostaglandin production by hyperproliferative keratinocyte cultures: Effect of themitogens 8-Bromocyclic AMP and TPA. (Vols. 32). pp. 818A. Clin Res.

Fairley, J. A., Hogan, V. A. & Marcelo, C. L. (1984). Localization of calmodulin in the epidermis. (Vols. 32). pp. 582A. Clin Res.

Fairley, J. A., Weiss, J., Madison, K. C. & Marcelo, C. L. (1984). Increased prostaglandin synthesis by low calcium regulated keratinocytes. (Vols. 32). pp. 817A. Clin Res.

LaRouere, J., Fairley, J. A., Grekin, R. & Marcelo, C. L. (1984). Calmodulin levels in skin tumors. (Vols. 32). pp. 597A. Clin Res.

Wong, R. D., Ellis, C. N. & Fairley, J. A. (1984). Dermatographism: a review. J Amer Acad Dermatol, 11(4 Pt 1), 643-652. PMID: 6386900.

Marcelo, C. L., Gold, R. C. & Fairley, J. A. (1984). Effect of 1.2mM calcium, triamcinolone acetonide, and retinoids on low-calcium regulated keratinocyte differentiation. Br Dermatol, 111(27), 64-72. PMID: 6204678.

Fairley, J. A., Hogan, V. A. & Marcelo, C. L. (1983). Epidermal keratinocyte calmodulin: Shifts in hyperproliferative systems. (Vols. 31). pp. 565A. Clin Res.

Marcelo, C. L., Gold, R. & Fairley, J. A. (1983). Effect of triamcinalone acetonide, retinoids and 1.2mm Ca++ on low calcium (0.01mM) regulated keratinocyte differentiation. CIRD, Valbonne, France.

King, A. J., Fairley, J. A. & Rasmussen, J. E. (1983). Disseminated cutaneous mycobacteriamarinum infection. Arch Dermatol, 119(3), 268-70. PMID: 6824363.

Fairley, J. A., Rasmussen, J. E. (1983). Comparison of stratum corneum thickness in children and adults. J Amer Acad Dermatol, 8(5), 652-4. PMID: 6863621.

Fairley, J. A., Tong, P. & Duell, E. A. (1982). Effect of 8-BrcAMP on epidermal cell protein phosphorylation. (Vols. 30). pp. 58A. Clin Res.

Fairley, J. A., Marcelo, C. L. (1982). Activity of the de novo and salvage pathways of nucleotide synthesis. (Vols. 30). pp. 810A. Clin Res.

Fairley, J. A., Dubin, H. V. (1979). Collagen vascular disease. Perspec Ophthal, 3, 203-211.