Featured 2018 Publications of FOEDRC Members

E. Dale Abel, MD, PhD:

  • Ock S, Lee WS, Kim HM, Park KS, Kim YK, Kook H, Park WJ, Lee TJ, Abel ED, Kim J. Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts. Biochim Biophys Acta. 2018 Jan 31;1864(4 Pt A):1183-1191. doi: 10.1016/j.bbadis.2018.01.022. [Epub ahead of print] PubMed PMID: 29378301.
  • Swarup A, Bell BA, Du J, Han JYS, Soto J, Abel ED, Bravo-Nuevo A, FitzGerald PG, Peachey NS, Philp NJ. Deletion of GLUT1 in mouse lens epithelium leads to cataract formation. Exp Eye Res. 2018 Mar 28. pii: S0014-4835(17)30668-1. doi: 10.1016/j.exer.2018.03.021. [Epub ahead of print] PubMed PMID: 29604281.
  • Zhang Z, Zi Z, Lee EE, Zhao J, Contreras DC, South AP, Abel ED, Chong BF, Vandergriff T, Hosler GA, Scherer PE, Mettlen M, Rathmell JC, DeBerardinis RJ, Wang RC. Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. Nat Med. 2018 Apr 16. doi: 10.1038/s41591-018-0003-0. [Epub ahead of print] PubMed PMID: 29662201.

Michael Abramoff, MD, PhD:

  • van der Heijden AA, Abramoff MD, Verbraak F, van Hecke MV, Liem A, Nijpels G. Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System. Acta Ophthalmol. 2018 Feb;96(1):63-68. doi: 10.1111/aos.13613. Epub 2017 Nov 27. PubMed PMID: 29178249.

Christopher Adams, MD, PhD:

  • Stebounova L, Ebert SM, Murry LT, Adams CM, Murry DJ. Rapid and Sensitive Quantification of Ursolic Acid and Oleanolic Acid in Human Plasma Using Ultra-performance Liquid Chromatography-Mass Spectrometry. J Chromatogr Sci. 2018 Apr 26. doi: 10.1093/chromsci/bmy038. [Epub ahead of print] PubMed PMID: 29701757.

Ethan Anderson, PhD:

  • Efird JT, Jindal C, Kiser AC, Akhter SA, Crane PB, Kypson AP, Sverdlov AL, Davies SW, Kindell LC, Anderson EJ. Increased risk of atrial fibrillation among patients undergoing coronary artery bypass graft surgery while receiving nitrates and antiplatelet agents. J Int Med Res. 2018 Jan 1:300060518773934. doi: 10.1177/0300060518773934. [Epub ahead of print] PubMed PMID: 29808744.

Michael Anderson, MD, PhD:

  • Anderson MG, Meyer KJ, Hedberg-Buenz A, Fingert JH. Update on Animal Models of Exfoliation Syndrome. J Glaucoma. 2018 Feb 6. doi: 10.1097/IJG.0000000000000911. [Epub ahead of print] PubMed PMID: 29419647.
  • Wang C, Brancusi F, Valivullah ZM, Anderson MG, Cunningham D, Hedberg-Buenz A, Power B, Simeonov D, Gahl WA, Zein WM, Adams DR, Brooks B. A novel iris transillumination grading scale allowing flexible assessment with quantitative image analysis and visual matching. Ophthalmic Genet. 2018 Jan-Feb;39(1):41-45. doi: 10.1080/13816810.2017.1342134. Epub 2017 Jul 25. PubMed PMID: 28742462.

James Ankrum, PhD:

  • Klingelhutz AJ, Gourronc FA, Chaly A, Wadkins DA, Burand AJ, Markan KR, Idiga SO, Wu M, Potthoff MJ, Ankrum JA. Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery. Sci Rep. 2018 Jan 11;8(1):523. doi: 10.1038/s41598-017-19024-z. PubMed PMID: 29323267.

Wei Bao, MD, PhD:

  • Liu B, Sun Y, Snetselaar LG, Sun Q, Yang Q, Zhang Z, Liu L, Hu FB, Bao W. Association between Plasma trans-Fatty Acid Concentrations and Diabetes in a Nationally Representative Sample of U.S. Adults. J Diabetes. 2018 Feb 15. doi: 10.1111/1753-0407.12652. [Epub ahead of print] PubMed PMID: 29446544.
  • Yang T, Zhang L, Bao W, Rong S. Nutritional composition of breast milk in Chinese women: a systematic review. Asia Pac J Clin Nutr. 2018;27(3):491-502. doi: 10.6133/apjcn.042017.13. PubMed PMID: 29737794.
  • Rawal S, Olsen SF, Grunnet LG, Ma RC, Hinkle SN, Granström C, Wu J, Yeung E, Mills JL, Zhu Y, Bao W, Ley SH, Hu FB, Damm P, Vaag A, Tsai MY, Zhang C. Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy. Diabetes Care. 2018 May 4. pii: dc172629. doi: 10.2337/dc17-2629. [Epub ahead of print] PubMed PMID: 29728364.
  • Lehmler HJ, Gadogbe M, Liu B, Bao W. Environmental tin exposure in a nationally representative sample of U.S. adults and children: The National Health and Nutrition Examination Survey 2011-2014. Environ Pollut. 2018 May 12;240:599-606. doi: 10.1016/j.envpol.2018.05.019. [Epub ahead of print] PubMed PMID: 29763863.

Melissa Bates, PhD:

  • Bates ML, Anagnostopoulos PV, Nygard C, Torgeson J, Reichert J, Galambos C, Eldridge MW, Lamers LJ. Consequences of an early catheter-based intervention on pulmonary artery growth and right ventricular myocardial function in a pig model of pulmonary artery stenosis. Catheter Cardiovasc Interv. 2018 Mar 30. doi: 10.1002/ccd.27593. [Epub ahead of print] PubMed PMID: 29602248.
  • Bates ML, Welch BT, Randall JT, Petersen-Jones HG, Limberg JK. Carotid body size measured by computed tomographic angiography in individuals born prematurely. Respir Physiol Neurobiol. 2018 May 24. pii: S1569-9048(18)30033-8. doi: 10.1016/j.resp.2018.05.010. [Epub ahead of print] PubMed PMID: 29803761.

Gail Bishop, PhD: 

  • Wallis AM, Bishop GA. TRAF3 regulation of inhibitory signaling pathways in B and T lymphocytes by kinase and phosphatase localization. J Leukoc Biol. 2018 Jan 17. doi: 10.1002/JLB.2MIR0817-339RR. [Epub ahead of print] Review. PubMed PMID: 29345428.

Sue Bodine, PhD:

  • Miller BF, Bodine SC. A New Cover and Updated Scope for JAPPL. J Appl Physiol  (1985). 2018 Jan 4. doi: 10.1152/japplphysiol.00004.2018. [Epub ahead of print] PubMed PMID: 29357484.
  • Hughes DC, Marcotte GR, Baehr LM, West DWD, Marshall AG, Ebert SM, Davidyan A, Adams CM, Bodine SC, Baar K. Alterations in the muscle force transfer apparatus in aged rats during unloading and reloading: Impact of microRNA-31. J Physiol. 2018 May 3. doi: 10.1113/JP275833. [Epub ahead of print] PubMed PMID: 29726007.

Ryan Boudreau, PhD:

  • Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL. A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality. J Clin Invest. 2018 Feb 19. pii: 95710. doi: 10.1172/JCI95710. [Epub ahead of print] PubMed PMID: 29457789.

Charles Brenner, PhD:

  • Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R. Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. Cell Metab. 2018 Mar 6;27(3):667-676.e4. doi: 10.1016/j.cmet.2018.02.001. PubMed PMID: 29514072.

Trudy Burns, MPH, PhD, FAHA:

  • Chen C, Zhang X, Guo J, Jin D, Letuchy EM, Burns TL, Levy SM, Hoffman EA, Saha PK. Quantitative imaging of peripheral trabecular bone microarchitecture using MDCT. Med Phys. 2018 Jan;45(1):236 249. doi: 10.1002/mp.12632. Epub 2017 Nov 23. PubMed PMID: 29064579.

Lucas Carr, PhD:

  • Benzo RM, Kruse NT, Hughes WE, Casey DP, Carr LJ. Acute Effects of Interrupting Sitting on Discomfort and Alertness of Office Workers. J Occup Environ Med. 2018 Mar 30. doi: 10.1097/JOM.0000000000001329. [Epub ahead of print] PubMed PMID: 29608539.

Darren Casey, PhD:

  • Iwamoto E, Bock JM, Casey DP. Blunted shear-mediated dilation of the internal but not common carotid artery in response to lower body negative pressure. J Appl Physiol (1985). 2018 Feb 15. doi: 10.1152/japplphysiol.01011.2017. [Epub ahead of print] PubMed PMID: 29446714.
  • Hughes WE, Kruse NT, Casey DP. Age-associated impairments in contraction-induced rapid onset vasodilatation within the forearm are independent of mechanical factors. Exp Physiol. 2018 Mar 12. doi: 10.1113/EP086908. [Epub ahead of print] PubMed PMID: 29528524.
  • Iwamoto E, Bock JM, Casey DP. High-Intensity Exercise Enhances Conduit Artery Vascular Function in Older Adults. Med Sci Sports Exerc. 2018 Jan;50(1):124-130. doi: 10.1249/MSS.0000000000001405. PubMed PMID: 28817509; PubMed Central PMCID: PMC5735000.
  • Kruse NT, Hughes WE, Ueda K, Hanada S, Feider AJ, Iwamoto E, Bock JM, Casey DP. Impaired modulation of postjunctional α(1) -, but not α(2) –adrenergic vasoconstriction in contracting forearm muscle of postmenopausal women. J Physiol. 2018 Apr 30. doi: 10.1113/JP275777. [Epub ahead of print] PubMed PMID: 29708589.
  • Kruse NT, Hughes WE, Casey DP. Mechanistic insights into the modulatory role of the mechanoreflex on central hemodynamics using passive leg movement in humans. J Appl Physiol (1985). 2018 May 17. doi: 10.1152/japplphysiol.01085.2017. [Epub ahead of print] PubMed PMID: 29771607.

Mark Chapleau, PhD:

  • Sabharwal R, Mason BN, Kuburas A, Abboud FM, Russo AF, Chapleau MW. Increased receptor activity-modifying protein 1 in the nervous system is sufficient to protect against autonomic dysregulation and hypertension. J Cereb Blood Flow Metab. 2018 Jan 1:271678X17751352. doi: 10.1177/0271678X17751352. [Epub ahead of print] PubMed PMID: 29297736.
  • Larson RA, Chapleau MW. Increased cardiac sympathetic activity: Cause or compensation in vasovagal syncope? Clin Auton Res. 2018 Apr 3. doi: 10.1007/s10286-018-0524-0. [Epub ahead of print] PubMed PMID: 29616375.

Huxing Cui, PhD:

  • Saito K, Cui H. Emerging Roles of Estrogen-Related Receptors in the Brain: Potential Interactions with Estrogen Signaling. Int J Mol Sci. 2018 Apr 5;19(4). pii: E1091. doi: 10.3390/ijms19041091. Review. PubMed PMID: 29621182.

Brandon Davies, PhD:

  • Davies BSJ. Can targeting ANGPTL proteins improve glucose tolerance? Diabetologia. 2018 Apr 4. doi: 10.1007/s00125-018-4604-4. [Epub ahead of print] PubMed PMID: 29619530.

John Engelhardt, PhD:

  • Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF. Infection is Not Required for Mucoinflammatory Lung Disease in CFTR-knockout Ferrets. Am J Respir Crit Care Med. 2018 Jan 12. doi: 10.1164/rccm.201708-1616OC. [Epub ahead of print] PubMed PMID: 29327941.
  • Johnson MB, Sun X, Kodani A, Borges-Monroy R, Girskis KM, Ryu SC, Wang PP, Patel K, Gonzalez DM, Woo YM, Yan Z, Liang B, Smith RS, Chatterjee M, Coman D, Papademetris X, Staib LH, Hyder F, Mandeville JB, Grant PE, Im K, Kwak H, Engelhardt JF, Walsh CA, Bae BI. Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size. Nature. 2018 Apr 11. doi: 10.1038/s41586-018-0035-0. [Epub ahead of print] PubMed PMID: 29643508.
  • Bridges CS, Miller PS, Lidbury JA, Suchodolski JS, Yi Y, Engelhardt JF, Steiner JM. Validation of a radioimmunoassay of serum trypsin-like immunoreactivity in ferrets. J Vet Diagn Invest. 2018 Apr 1:1040638718774387. doi: 10.1177/1040638718774387. [Epub ahead of print] PubMed PMID: 29717637.

Frank Faraci, PhD:

  • De Silva TM, Modrick ML, Dabertrand F, Faraci FM. Changes in Cerebral Arteries and Parenchymal Arterioles With Aging: Role of Rho Kinase 2 and Impact of Genetic Background. Hypertension. 2018 Mar 12. pii: HYPERTENSIONAHA.118.10865. doi: 10.1161/HYPERTENSIONAHA.118.10865. [Epub ahead of print] PubMed PMID: 29531174.
  • Faraci FM. Watching Small Vessel Disease Grow. Circ Res. 2018 Mar 16;122(6):810-812. doi: 10.1161/CIRCRESAHA.118.312762. PubMed PMID: 29700083; PubMed Central PMCID: PMC5926815.
  • De Silva TM, Li Y, Kinzenbaw DA, Sigmund CD, Faraci FM. Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. Hypertension. 2018 May 7. pii: HYPERTENSIONAHA.117.10799. doi: 10.1161/HYPERTENSIONAHA.117.10799. [Epub ahead of print] PubMed PMID: 29735632.

David Frisvold, PhD:

  • Cawley J, Willage B, Frisvold D. Pass-Through of a Tax on Sugar-Sweetened Beverages at the Philadelphia International Airport. JAMA. 2018 Jan 16;319(3):305-306. doi: 10.1001/jama.2017.16903. PubMed PMID: 29071342.

Bernd Fritzsch, PhD:

  • Marchini L, Ettinger R, Chen X, Kossioni A, Tan H, Tada S, Ikebe K, Dosumu EB, Oginni FO, Akeredolu PA, Butali A, Donnelly L, Brondani M, Fritzsch B, Adeola HA. Geriatric dentistry education and context in a selection of countries in 5 continents. Spec Care Dentist. 2018 Mar 30. doi: 10.1111/scd.12281. [Epub ahead of print] PubMed PMID: 29603314.

Katherine Gibson-Corley, DVM, PhD:

  • Gibbins KJ, Gibson-Corley KN, Brown AS, Wieben M, Law RC, Fung CM. Effects of excess thromboxane A2 on placental development and nutrient transporters in a Mus musculus model of fetal growth restriction. Biol Reprod. 2018 Jan 17. doi: 10.1093/biolre/ioy006. [Epub ahead of print] PubMed PMID: 29351577.
  • Rotti PG, Xie W, Poudel A, Yi Y, Sun X, Tyler SR, Uc A, Norris AW, Hara M, Engelhardt JF, Gibson-Corley KN. Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets. Am J Pathol. 2018 Jan 20. pii: S0002-9440(17)30728-9. doi: 10.1016/j.ajpath.2017.12.015. [Epub ahead of print] PubMed PMID: 29366680.
  • Fricke EM, Elgin TG, Gong H, Reese J, Gibson-Corley KN, Weiss RM, Zimmerman K, Bowdler NC, Kalantera KM, Mills DA, Underwood MA, McElroy SJ. Lipopolysaccharide-induced maternal inflammation induces direct placental injury without alteration in placental blood flow and induces a secondary fetal intestinal injury that persists into adulthood. Am J Reprod Immunol. 2018 Jan 25. doi: 10.1111/aji.12816. [Epub ahead of print] PubMed PMID: 29369434.
  • Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ. Pharmacologic ascorbate (P-AscH(-)) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma. Clin Exp Metastasis. 2018 Feb 2. doi: 10.1007/s10585-018-9876 z. [Epub ahead of print] PubMed PMID: 29396728.
  • Gadupudi GS, Elser BA, Sandgruber FA, Li X, Gibson-Corley KN, Robertson LW. PCB126 inhibits the activation of AMPK-CREB signal transduction required for energy sensing in liver. Toxicol Sci. 2018 Feb 20. doi: 10.1093/toxsci/kfy041. [Epub ahead of print] PubMed PMID: 29474705.

Mark Greiner, MD:

  • Skeie JM, Aldrich BT, Goldstein AS, Schmidt GA, Reed CR, Greiner MA. Proteomic analysis of corneal endothelial cell-descemet membrane tissues reveals influence of insulin dependence and disease severity in type 2 diabetes mellitus. PLoS One. 2018 Mar 12;13(3):e0192287. doi: 10.1371/journal.pone.0192287. eCollection 2018. PubMed PMID: 29529022.
  • Wagoner MD, Bohrer LR, Aldrich BT, Greiner MA, Mullins RF, Worthington KS, Tucker BA, Wiley LA. Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells. Biol Open. 2018 Apr 23. pii: bio.032102. doi: 10.1242/bio.032102. [Epub ahead of  print] PubMed PMID: 29685994.

Justin Grobe, PhD:

  • Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK. Elevated Vasopressin in Pregnant Mice Induces T Helper Subset Alterations Consistent with Human Preeclampsia. Clin Sci (Lond). 2018 Jan 25. pii: CS20171059. doi: 10.1042/CS20171059. [Epub ahead of print] PubMed PMID: 29371289.
  • Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL. Angiotensin AT(1A) Receptors Expressed in Vasopressin-Producing Cells of the Supraoptic Nucleus Contribute to the Osmotic Control of Vasopressin. Am J Physiol Regul Integr Comp Physiol. 2018 Jan 24. doi: 10.1152/ajpregu.00435.2017. [Epub ahead of print] PubMed PMID: 29364700.
  • Morselli LL, Claflin KE, Cui H, Grobe JL. Control of Energy Expenditure by AgRP Neurons of the Arcuate Nucleus: Neurocircuitry, Signaling Pathways, and Angiotensin. Curr Hypertens Rep. 2018 Mar 19;20(3):25. doi: 10.1007/s11906-018-0824-8. Review. PubMed PMID: 29556733.
  • Perschbacher KJ, Deng G, Fisher RA, Gibson-Corley KN, Santillan MK, Grobe JL. Regulators of G-Protein Signaling in Cardiovascular Function During Pregnancy. Physiol Genomics. 2018 Apr 27. doi: 10.1152/physiolgenomics.00037.2018. [Epub ahead of print] PubMed PMID: 29702036.

Isabella Grumbach, MD, PhD:

  • Dogan MV, Grumbach IM, Michaelson JJ, Philibert RA. Integrated genetic and epigenetic prediction of coronary heart disease in the Framingham Heart Study. PLoS One. 2018 Jan 2;13(1):e0190549. doi: 10.1371/journal.pone.0190549. eCollection 2018. PubMed PMID: 29293675.
  • Nguyen EK, Koval OM, Noble P, Broadhurst K, Allamargot C, Wu M, Strack S, Thiel WH, Grumbach IM. CaMKII (Ca(2+)/Calmodulin-Dependent Kinase II) in Mitochondria of Smooth Muscle Cells Controls Mitochondrial Mobility, Migration, and Neointima Formation. Arterioscler Thromb Vasc Biol. 2018 Mar 29. pii: ATVBAHA.118.310951. doi: 10.1161/ATVBAHA.118.310951. [Epub ahead of print] PubMed PMID: 29599132.
  • Pennington SM, Klutho PR, Xie L, Broadhurst K, Koval OM, McCormick ML, Spitz DR, Grumbach IM. Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription. Redox Biol. 2018 Jun;16:401-413. doi: 10.1016/j.redox.2018.04.001. Epub 2018 Apr 3. PubMed PMID: 29649787.

Kaikobad Irani, MD:

  • Piao S, Lee JW, Nagar H, Jung SB, Choi S, Kim S, Lee I, Kim SM, Shin N, Lee YR, Lee SD, Park JB, Irani K, Won M, Hur GM, Jeon BH, Kim DW, Kim CS. CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation. PLoS One. 2018 Feb 23;13(2):e0192693. doi: 10.1371/journal.pone.0192693. eCollection 2018. PubMed PMID: 29474366.

Kathleen Janz, EdD:

  • Janz KF, Baptista F. Bone Strength and Exercise During Youth-The Year That Was 2017. Pediatr Exerc Sci. 2018 Feb 19:1-4. doi: 10.1123/pes.2017-0295. [Epub ahead of print] PubMed PMID: 29457753.
  • Baquero B, Kava CM, Ashida S, Daniel-Ulloa J, Laroche HH, Haines H, Bucklin R, Maldonado A, Coronado Garcia M, Berto S, Sewell D, Novak N, Janz K, Gates C, Parker EA. Active Ottumwa: Adapting Evidence-Based Recommendations to Promote Physical Activity in a Micropolitan New Destination Community. Int J Environ Res Public Health. 2018 May 4;15(5). pii: E917. doi: 10.3390/ijerph15050917. PubMed PMID: 29734709.

Alan Johnson, PhD:

  • Zhang YP, Huo YL, Fang ZQ, Wang XF, Li JD, Wang HP, Peng W, Johnson AK, Xue B. Maternal High Fat Diet Acts on the Brain to Induce Baroreflex Dysfunction and Sensitization of Angiotensin II-Induced Hypertension in Adult Offspring. Am J Physiol Heart Circ Physiol. 2018 Jan 26. doi: 10.1152/ajpheart.00698.2017. [Epub ahead of print] PubMed PMID: 29373045.
  • Kopf PG, Phelps LE, Schupbach CD, Johnson AK, Peuler JD. Differential effects of long-term slow-pressor and subpressor angiotensin II on contractile and relaxant reactivity of resistance versus conductance arteries. Physiol Rep. 2018 Mar;6(5). doi: 10.14814/phy2.13623. PubMed PMID: 29504268.
  • Hardy RN, Simsek ZD, Curry B, Core SL, Beltz T, Xue B, Johnson AK, Thunhorst RL, Curtis KS. Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. Physiol Behav. 2018 Mar 5. pii: S0031-9384(18)30126-4. doi: 10.1016/j.physbeh.2018.03.005. [Epub ahead of print] PubMed PMID: 29518407.

Robert Kerns, PhD:

  • Towle TR, Kulkarni CA, Oppegard LM, Williams BP, Picha TA, Hiasa H, Kerns RJ. Design, synthesis, and evaluation of novel N-1 fluoroquinolone derivatives: Probing for binding contact with the active site tyrosine of gyrase. Bioorg Med Chem Lett. 2018 Mar 30. pii: S0960-894X(18)30290-7. doi: 10.1016/j.bmcl.2018.03.085. [Epub ahead of print] PubMed PMID: 29661533.

Helena Laroche, MD, MS:

  • Metcalf KM, Baquero BI, Coronado Garcia ML, Francis SL, Janz KF, Laroche HH, Sewell DK. Calibration of the global physical activity questionnaire to Accelerometry measured physical activity and sedentary behavior. BMC Public Health. 2018 Mar 27;18(1):412. doi: 10.1186/s12889-018-5310-3. PubMed PMID: 29587694; PubMed Central PMCID: PMC5870179.

Brian O'Neill, MD, PhD:

  • Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2018 Mar 1;128(3):1199. doi: 10.1172/JCI99009. Epub 2018 Mar 1. PubMed PMID: 29493547.

Gary Pierce, PhD:

  • Holwerda SW, Luehrs RE, Gremaud AL, Wooldridge NA, Stroud AK, Fiedorowicz JG, Abboud FM, Pierce GL. Relative burst amplitude of muscle sympathetic nerve activity is an indicator of altered sympathetic outflow in chronic anxiety. J Neurophysiol. 2018 Mar 14. doi: 10.1152/jn.00064.2018. [Epub ahead of print] PubMed PMID: 29537916.
  • Holwerda SW, Holland MT, Reddy CG, Pierce GL. Femoral vascular conductance and peroneal muscle sympathetic nerve activity responses to acute epidural spinal cord stimulation in humans. Exp Physiol. 2018 Mar 30. doi: 10.1113/EP086945. [Epub ahead of print] PubMed PMID: 29603444.
  • Pierce GL. Initiating life-long aerobic exercise 4-5 days/week before or near age 50 years: is this the "holy-grail" of preventing age-related central artery stiffness? J Physiol. 2018 May 22. doi: 10.1113/JP276253. [Epub ahead of print] PubMed PMID: 29786836.

Robert Piper, PhD:

  • Pearson G, Chai B, Vozheiko T, Liu X, Kandarpa M, Piper RC, Soleimanpour SA. Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates β-Cell Mitophagy. Diabetes. 2018 Feb;67(2):265-277. doi: 10.2337/db17-0321. Epub 2017 Nov 27. PubMed PMID: 29180353; PubMed Central PMCID: PMC5780060.

Linnea Polgreen, PhD:

  • Kennelty KA, Polgreen LA, Carter BL. Team-Based Care with Pharmacists to Improve Blood Pressure: a Review of Recent Literature. Curr Hypertens Rep. 2018 Jan 18;20(1):1. doi: 10.1007/s11906-018-0803-0. Review. PubMed PMID: 29349522.
  • Leira EC, Viscoli CM, Polgreen LA, Gorman M, Kernan WN; <collab>on behalf of the IRIS Trial Investigators</collab>. Distance from Home to Research Center: A Barrier to In-Person Visits but Not Treatment Adherence in a Stroke Trial. Neuroepidemiology. 2018 Mar 23;50(3-4):137-143. doi: 10.1159/000486315. [Epub ahead of print] PubMed PMID: 29587267.

Philip Polgreen, MD, MPH:

  • Simmering JE, Cavanaugh JE, Polgreen LA, Polgreen PM. Warmer weather as a risk factor for hospitalisations due to urinary tract infections. Epidemiol Infect. 2018 Jan 8:1-8. doi: 10.1017/S0950268817002965. [Epub ahead of print] PubMed PMID: 29307331.
  • Butler R, Monsalve M, Thomas GW, Herman T, Segre AM, Polgreen PM, Suneja M. Estimating Time Physicians and Other Healthcare Workers Spend with Patients in an Intensive Care Unit Using a Sensor Network. Am J Med. 2018 Apr 9. pii: S0002-9343(18)30296-1. doi: 10.1016/j.amjmed.2018.03.015. [Epub ahead of print] PubMed PMID: 29649458.
  • Polgreen LA, Riedle BN, Cavanaugh JE, Girotra S, London B, Schroeder MC, Polgreen PM. Estimated Cardiac Risk Associated With Macrolides and Fluoroquinolones Decreases Substantially When Adjusting for Patient Characteristics and Comorbidities. J Am Heart Assoc. 2018 Apr 21;7(9). pii: e008074. doi: 10.1161/JAHA.117.008074. PubMed PMID: 29680825.
  • Polgreen LA, Anthony C, Carr L, Simmering JE, Evans NJ, Foster ED, Segre AM, Cremer JF, Polgreen PM. The effect of automated text messaging and goal setting on pedometer adherence and physical activity in patients with diabetes: A randomized controlled trial. PLoS One. 2018 May 2;13(5):e0195797. doi: 10.1371/journal.pone.0195797. eCollection 2018. PubMed PMID: 29718931.

Matthew Potthoff, PhD:

  • Zhang P, Kuang H, He Y, Idiga SO, Li S, Chen Z, Yang Z, Cai X, Zhang K, Potthoff MJ, Xu Y, Lin JD. NRG1-Fc improves metabolic health via dual hepatic and central action. JCI Insight. 2018 Mar 8;3(5). pii: 98522. doi: 10.1172/jci.insight.98522. [Epub ahead of print] PubMed PMID: 29515030.
  • BonDurant LD, Potthoff MJ. Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis. Annu Rev Nutr. 2018 May 4. doi: 10.1146/annurev-nutr-071816-064800. [Epub ahead of print] PubMed PMID: 29727594.

Kamal Rahmouni, PhD:

  • Schmidt EA, Despas F, Pavy-Le Traon A, Czosnyka Z, Pickard JD, Rahmouni K, Pathak A, Senard JM. Intracranial Pressure Is a Determinant of Sympathetic Activity. Front Physiol. 2018 Feb 8;9:11. doi: 10.3389/fphys.2018.00011. eCollection 2018. PubMed PMID: 29472865; PubMed Central PMCID: PMC5809772.
  • Yoon YS, Tsai WW, Van de Velde S, Chen Z, Lee KF, Morgan DA, Rahmouni K, Matsumura S, Wiater E, Song Y, Montminy M. cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201805257. doi: 10.1073/pnas.1805257115. [Epub ahead of print] PubMed PMID: 29784793.

Jennifer Robinson, MD, MPH:

  • Bin Abdulhak AA, Vaughan-Sarrzin M, Kaboli P, Horwitz PA, Mosher H, Sigurdsson G, Walker NE, Wallace R, Robinson JG. Temporal Trends of High-Intensity Statin Therapy Among Veterans Treated With Percutaneous Coronary Intervention. J Am Heart Assoc. 2018 Mar 4;7(5). pii: e007370. doi: 10.1161/JAHA.117.007370. PubMed PMID: 29503265.
  • Navar AM, Peterson ED, Li S, Robinson JG, Roger VL, Goldberg AC, Virani S, Wilson PWF, Nanna MG, Lee LV, Elassal J, Wang TY. Prevalence and Management of Symptoms Associated With Statin Therapy in Community Practice: Insights From the PALM (Patient and Provider Assessment of Lipid Management) Registry. Circ Cardiovasc Qual Outcomes. 2018 Mar;11(3):e004249. doi: 10.1161/CIRCOUTCOMES.117.004249. PubMed PMID: 29545393; PubMed Central PMCID: PMC5858190.
  • Bin Abdulhak AA, Robinson JG. Optimizing Statins and Ezetimibe in Guideline-Focused Management. Cardiol Clin. 2018 May;36(2):221-223. doi: 10.1016/j.ccl.2017.12.003. Review. PubMed PMID: 29609751.
  • Navarese EP, Robinson JG, Kowalewski M, Kolodziejczak M, Andreotti F, Bliden K, Tantry U, Kubica J, Raggi P, Gurbel PA. Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis. JAMA. 2018 Apr 17;319(15):1566-1579. doi: 10.1001/jama.2018.2525. PubMed PMID: 29677301.
  • Ginsberg HN, Farnier M, Robinson JG, Cannon CP, Sattar N, Baccara-Dinet MT, Letierce A, Bujas-Bobanovic M, Louie MJ, Colhoun HM. Efficacy and Safety of Alirocumab in Individuals with Diabetes Mellitus: Pooled Analyses from Five Placebo-Controlled Phase 3 Studies. Diabetes Ther. 2018 May 19. doi: 10.1007/s13300-018-0439-8. [Epub ahead of print] PubMed PMID: 29779195.

Robert Roghair, MD:

  • Knott MH, Haskell SE, Strawser PE, Rice OM, Bonthius NT, Movva VC, Reinking BE, Roghair RD. Neonatal Growth Restriction Slows Cardiomyocyte Development and Reduces Adult Heart Size. Anat Rec (Hoboken). 2018 May 5. doi: 10.1002/ar.23851. [Epub ahead of print] PubMed PMID: 29729218.

Thomas Rutkowski, PhD:

  • Rutkowski DT. Liver function and dysfunction - a unique window into the physiological reach of ER stress and the unfolded protein response. FEBS J. 2018 Jan 23. doi: 10.1111/febs.14389. [Epub ahead of print] Review. PubMed PMID: 29360258.
  • Diedrichs DR, Gomez JA, Huang CS, Rutkowski DT, Curtu R. A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response. Mol Biol Cell. 2018 Apr 18:mbcE17090565. doi: 10.1091/mbc.E17-09-0565. [Epub ahead of print] PubMed PMID: 29668363.

Rajan Sah, MD, PhD:

  • Kang C, Xie L, Gunasekar SK, Mishra A, Zhang Y, Pai S, Gao Y, Kumar A, Norris AW, Stephens SB, Sah R. SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia. Nat Commun. 2018 Jan 25;9(1):367. doi: 10.1038/s41467-017-02664-0. PubMed PMID: 29371604; PubMed Central PMCID: PMC5785485.

Diane Slusarski, BA, BS, PhD:

  • Marsden AN, Derry SW, Schneider I, Scott CA, Westfall TA, Brastrom LK, Shea MA, Dawson DV, Slusarski DC. The Nkd EF-hand domain modulates divergent wnt signaling outputs in zebrafish. Dev Biol. 2018 Feb 1;434(1):63-73. doi: 10.1016/j.ydbio.2017.11.012. Epub 2017 Nov 24. PubMed PMID: 29180104.
  • Eno C, Gomez T, Slusarski DC, Pelegri F. Slow calcium waves mediate furrow microtubule reorganization and germ plasm compaction in the early zebrafish embryo. Development. 2018 Apr 9. pii: dev.156604. doi: 10.1242/dev.156604. [Epub  ahead of print] PubMed PMID: 29632136.
  • Fuller TD, Westfall TA, Das T, Dawson DV, Slusarski DC. High-throughput behavioral assay to investigate seizure sensitivity in zebrafish implicates ZFHX3 in epilepsy. J Neurogenet. 2018 May 2:1-14. doi: 10.1080/01677063.2018.1445247. [Epub ahead of print] PubMed PMID: 29718741.

Linda Snetselaar, RD, PhD:

  • Clark-Cutaia MN, Sevick MA, Thurheimer-Cacciotti J, Hoffman LA, Snetselaar L, Burke LE, Zickmund SL. Perceived Barriers to Adherence to Hemodialysis Dietary Recommendations. Clin Nurs Res. 2018 May 1:1054773818773364. doi: 10.1177/1054773818773364. [Epub ahead of print] PubMed PMID: 29732932.
  • Jung S, Goloubeva O, Hylton N, Klifa C, LeBlanc E, Shepherd J, Snetselaar L, Van Horn L, Dorgan JF. Intake of dietary carbohydrates in early adulthood and adolescence and breast density among young women. Cancer Causes Control. 2018 May 25. doi: 10.1007/s10552-018-1040-1. [Epub ahead of print] PubMed PMID: 29802491.
  • Chlebowski RT, Aragaki AK, Anderson GL, Simon MS, Manson JE, Neuhouser ML, Pan K, Stefanic ML, Rohan TE, Lane D, Qi L, Snetselaar L, Prentice RL. Association of Low-Fat Dietary Pattern With Breast Cancer Overall Survival: A Secondary Analysis of the Women's Health Initiative Randomized Clinical Trial. JAMA Oncol. 2018 May 24:e181212. doi: 10.1001/jamaoncol.2018.1212. [Epub ahead of print] PubMed PMID: 29800122.

Elliott Sohn, MD:

  • Abramoff MD, Fort PE, Han IC, Jayasundera KT, Sohn EH, Gardner TW. Approach for a Clinically Useful Comprehensive Classification of Vascular and Neural Aspects of Diabetic Retinal Disease. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):519-527. doi: 10.1167/iovs.17-21873. PubMed PMID: 29372250; PubMed Central PMCID: PMC5786342.

Long Sheng-Song, MD, MS:

  • Guo A, Chen R, Wang Y, Huang CK, Chen B, Kutschke W, Hong J, Song LS. Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca(2+)](i) in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity. J Mol Cell Cardiol. 2018 Jan 4. pii: S0022-2828(18)30012-9. doi: 10.1016/j.yjmcc.2018.01.003. [Epub ahead of print] PubMed PMID: 29307535.
  • Yan J, Zhao W, Thomson JK, Gao X, DeMarco DM, Carrillo E, Chen B, Wu X, Ginsburg KS, Bakhos M, Bers DM, Anderson ME, Song LS, Fill M, Ai X. Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis. Circ Res. 2018 Jan 19. pii: CIRCRESAHA.117.312536. doi: 10.1161/CIRCRESAHA.117.312536. [Epub ahead of print] PubMed PMID: 29352041.
  • Chiamvimonvat N, Song LS. LRRC10 (Leucine-Rich Repeat Containing Protein 10) and REEP5 (Receptor Accessory Protein 5) as Novel Regulators of Cardiac Excitation-Contraction Coupling Structure and Function. J Am Heart Assoc. 2018 Feb 3;7(3). pii: e008260. doi: 10.1161/JAHA.117.008260. PubMed PMID: 29431105.
  • Yan J, Thomson JK, Zhao W, Gao X, Huang F, Chen B, Liang Q, Song LS, Fill M, Ai X. Role of Stress Kinase JNK in Binge Alcohol-Evoked Atrial Arrhythmia. J Am Coll Cardiol. 2018 Apr 3;71(13):1459-1470. doi: 10.1016/j.jacc.2018.01.060. PubMed PMID: 29598867.

Milan Sonka, PhD:

  • Pazdernik M, Chen Z, Bedanova H, Kautzner J, Melenovsky V, Karmazin V, Malek I, Tomasek A, Ozabalova E, Krejci J, Franekova J, Wahle A, Zhang H, Kovarnik T, Sonka M. Early detection of cardiac allograft vasculopathy using highly automated 3-dimensional optical coherence tomography analysis. J Heart Lung Transplant. 2018 Apr 6. pii: S1053-2498(18)31429-3. doi: 10.1016/j.healun.2018.04.002. [Epub  ahead of print] PubMed PMID: 29706574.

Douglas Spitz, PhD:

  • Heer CD, Davis AB, Riffe DB, Wagner BA, Falls KC, Allen BG, Buettner GR, Beardsley RA, Riley DP, Spitz DR. Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner. Antioxidants (Basel). 2018 Jan 19;7(1). pii: E18. doi: 10.3390/antiox7010018. PubMed PMID: 29351198.
  • Rashmi R, Huang X, Floberg JM, Elhammali A, McCormick ML, Patti GJ, Spitz DR, Schwarz JK. Radio-resistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism. Cancer Res. 2018 Jan 16. pii: canres.2367.2017. doi: 10.1158/0008-5472.CAN-17-2367. [Epub ahead of print] PubMed PMID: 29339540.

Eva Tsalikian, MD:

  • Fox LA, Hershey T, Mauras N, Arbeláez AM, Tamborlane WV, Buckingham B, Tsalikian E, Englert K, Raman M, Jo B, Shen H, Reiss A, Mazaika P; Diabetes Research in Children Network (DirecNet). Persistence of abnormalities in white matter in children with type 1 diabetes. Diabetologia. 2018 Apr 13. doi: 10.1007/s00125-018-4610-6. [Epub ahead of print] PubMed PMID: 29654376.
  • Afifi T, Granger D, Ersig A, Tsalikian E, Shahnazi A, Davis S, Harrison K, Acevedo Callejas M, Scranton A. Testing the theory of resilience and relational load (TRRL) in families with type I diabetes. Health Commun. 2018 Apr 18:1-13. doi: 10.1080/10410236.2018.1461585. [Epub ahead of print] PubMed PMID: 29667488.

Aliya Uc, MD:

  • Abu-El-Haija M, Kumar S, Quiros JA, Balakrishnan K, Barth B, Bitton S, Eisses JF, Foglio EJ, Fox V, Francis D, Freeman AJ, Gonska T, Grover AS, Husain SZ, Kumar R, Lapsia S, Lin T, Liu QY, Maqbool A, Sellers ZM, Szabo F, Uc A, Werlin SL, Morinville VD. Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report From the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee. J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):159-176. doi: 10.1097/MPG.0000000000001715. PubMed PMID: 29280782.
  • Párniczky A, Abu-El-Haija M, Husain S, Lowe M, Oracz G, Sahin-Tóth M, Szabó FK, Uc A, Wilschanski M, Witt H, Czakó L, Grammatikopoulos T, Rasmussen IC, Sutton R, Hegyi P. EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis. Pancreatology. 2018 Jan 4. pii: S1424-3903(18)30001-2. doi: 10.1016/j.pan.2018.01.001. [Epub ahead of print] Review. PubMed PMID: 29398347.
  • O'Malley Y, Rotti PG, Thornell IM, Vanegas Calderón OG, Febres-Aldana C, Durham K, Yao J, Li X, Zhu Z, Norris AW, Zabner J, Engelhardt JF, Uc A. DEVELOPMENT OF A POLARIZED PANCREATIC DUCTULAR CELL EPITHELIA FOR PHYSIOLOGICAL STUDIES. J Appl Physiol (1985). 2018 Mar 8. doi: 10.1152/japplphysiol.00043.2018. [Epub ahead of print] PubMed PMID: 29517421.
  • Abu-El-Haija M, Uc A, Werlin SL, Freeman AJ, Georgieva M, Pavkov DJ-, Kalnins D, Kochavi B, Koot BGP, Van Biervliet S, Walkowiak J, Wilschanski M, Morinville VD. Nutritional Considerations in Pediatric Pancreatitis: A Position Paper from the NASPGHAN Pancreas Committee, ESPGHAN Pancreas Working Group. J Pediatr Gastroenterol Nutr. 2018 May 8. doi: 10.1097/MPG.0000000000002023. [Epub ahead of print] PubMed PMID: 29746344.
  • Scheers I, Palermo JJ, Freedman S, Wilschanski M, Shah U, Abu-El-Haija M, Barth B, Fishman DS, Gariepy C, Giefer MJ, Heyman MB, Himes RW, Husain SZ, Lin TK, Liu Q, Lowe M, Mascarenhas M, Morinville V, Ooi CY, Perito ER, Piccoli DA, Pohl JF, Schwarzenberg SJ, Troendle D, Werlin S, Zimmerman B, Uc A, Gonska T. Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood: Consensus from INSPPIRE. J Pediatr Gastroenterol Nutr. 2018 May 9. doi: 10.1097/MPG.0000000000002028. [Epub ahead of print] PubMed PMID: 29746340.

Michael Welsh, MD:

  • Mao S, Shah AS, Moninger TO, Ostedgaard LS, Lu L, Tang XX, Thornell IM, Reznikov LR, Ernst SE, Karp PH, Tan P, Keshavjee S, Abou Alaiwa MH, Welsh MJ. Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling. Proc Natl Acad Sci U S A. 2018 Jan 22. pii: 201719177. doi: 10.1073/pnas.1719177115. [Epub ahead of print] PubMed PMID: 29358407.
  • Meyerholz DK, Stoltz DA, Gansemer ND, Ernst SE, Cook DP, Strub MD, LeClair EN, Barker CK, Adam RJ, Leidinger MR, Gibson-Corley KN, Karp PH, Welsh MJ, McCray PB  Jr. Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs. Lab Invest. 2018 Feb 21. doi: 10.1038/s41374-018-0026-7. [Epub ahead of print] PubMed PMID: 29467455.

Mark Yorek, PhD:

  • Coppey L, Davidson E, Shevalye H, Torres ME, Yorek MA. Effect of dietary oils on peripheral neuropathy-related endpoints in dietary obese rats. Diabetes Metab Syndr Obes. 2018 Apr 9;11:117-127. doi: 10.2147/DMSO.S159071. eCollection 2018. PubMed PMID: 29674850; PubMed Central PMCID: PMC5898889.