Logo for University of Iowa Health Care This logo represents the University of Iowa Health Care

Hands-on Bioinformatics Workshops

Ingenuity Pathway Analysis (IPA) Hands-on Workshop

Wednesday, December 20, 2023

8:30am-2:30pm

Location: Hardin Library for Health Sciences - Information Commons East

Agenda:

8:30am-9:00am

  • Check-in
  • Troubleshoot IPA access (highly encouraged)
  • Continental breakfast provided

9:00am-12:00pm

Pathway Analysis on 'Omic Data

  • Perform pathway analysis on user’s data
    • Dataset format, upload, and pathway/core analysis
    • Discover key biological mechanisms, regulators and targets
  • Compare different groups (time points, treatments, single cell clusters etc.)
    • Activity heatmap for pathways, regulators and biological functions
    • Compare contrast activity of pathways, biological functions and regulators
    • Discover condition specific biomarkers
  • Compare user data with public data
    • Analysis Match heatmap
  • Generate network using genes, chemicals, and disease of interest even without dataset
    • Predict activity of custom network using Molecule Activity Predictor

12:00pm-1:00pm

QIAGEN CLC Genomics Workbench Lunch and Learn - lunch is provided

 

1:00pm-2:30pm

Mine IPA's rich database for novel discoveries

Users will learn how to:

  • Leverage public data
    • Easily search and open pathway analyses of public data (GEO, SRA, etc.)
    • Study biological mechanisms and discover key regulators/drug targets
    • Identify gene signatures and key regulators common across datasets
  • Edit, expand, modify, and overlay public data on a network for genes, chemicals and diseases of interest
  • Study gene or biomarker expression across different tissues, diseases, cell types and more from public sources