Precision Genomic Medicine Conference

All of us strive to provide the best medical care we can.  By adding genetic data to our clinical armamentarium, we can refine our clinical examination, improve the care we deliver to our patients, and provide better and more targeted disease-specific treatment. This one-day conference targets health care professionals and provides an introduction to the integration of genomic data into routine patient management. We focus on the outstanding successes at the University of Iowa that are driving precision medicine, and highlight the benefits and the challenges associated with the routine the implementation of genetic data into standard practice.   

This conference is cosponsored by the Iowa Institute of Human Genetics, the UIHC Department of Pathology, the Holden Comprehensive Cancer Center, the Carver College of Medicine, and the Hardin Medical Library.

Venue: Medical Alumni Auditorium E331 GH

Tentative schedule

Friday, April 27, 2018

8:00-8:30 Check-in (coffee and tea provided)  


Brooks Jackson, MD, MBA, VPMA and Dean of the Carver College of Medicine


Introduction: Precision Medicine and Genomic Data

What is Precision Medicine - Its Promises and Limitations

Richard Smith, MD, Director of the Iowa Institute of Human Genetics


The Future is Here - Delivering on the Promise of Gene Therapy

Ed Stone, MD, PhD


Diagnostic Applications in Practice Today - Changing Diagnostic Algorithms

Renal disease - Christie Thomas, MD

Cardiovascular disease - Ferhaan Ahmad, MD, PhD

Neurodegenerative disease - Mike Shy, MD

Deafness - Hela Azaiez, PhD

10:15-10:30 Break  

Precision Genomic Medicine at UIHC and in the Community

  • Medical Genetics and the Application of Precision Genomic Medicine - John Bernat, MD, PhD
  • Precision Genomic Medicine in the Community: All of Us Program TBD

Keynote speaker: Pharmacogenomics: Precision Medicine and Drug Response

Richard Weinshilboum, MD - Mayo Clinic


Dr. Weinshilboum received B.A. and M.D. degrees from the University of Kansas, followed by residency training in Internal Medicine at the Massachusetts General Hospital in Boston.  He was also a Pharmacology Research Associate at the NIH in the laboratory of Nobel Laureate Dr. Julius Axelrod.  He is presently Professor of Pharmacology and Medicine and Dasburg Professor of Cancer Genomics Research at Mayo.  He also co-directs the Pharmacogenomics Program of the Mayo Center for Individualized Medicine.  Dr. Weinshilboum’s research has focused on pharmacogenomics, with over 425 manuscripts on that topic. His major area of research has been the pharmacogenetics of drug metabolism, with a focus on methylation and sulfation. He has also applied genome-wide “omics” to study drug response--especially the drug therapy of depression and breast cancer.  Dr. Weinshilboum has been the recipient of many awards including an Established Investigatorship of the American Heart Association, a Burroughs Wellcome Scholar Award in Clinical Pharmacology, the Oscar B. Hunter Award of the American Society for Clinical Pharmacology and Therapeutics, the ASPET Harry Gold Award and the Edvard Poulsson Award from the Norwegian Pharmacology Society.  He has also served on the Advisory Councils for two US NIH Institutes, the NIGMS and NHGRI.

11:45-12:00 Discussion  
12:00-1:00 Lunch  

Cancer Genomics in Diagnosis and Treatment

Current State of Molecular Diagnostics - TBD

Therapeutic Implications of Cancer Genomics - Kim Leslie, MD

Clinical Applications - Ken Nepple, MD

Immunotherapy/CAR T-Cell Therapy - Umar Farooq, MD

3:00-3:15 Break  

Perspective in Implementing Precision Genomic Medicine (panel discussion)



Panel Discussion



Audience Panel (persons who received the Drug Metabolism Test)

Moderator - Anya Prince, JD


Closing Remarks

Anne Kwitek, PhD