Iowa NeuroBank Core

Made possible through the Carver Trust and more than 200 brain donors, the Iowa NeuroBank Core is a collaborative effort of the Iowa Neuroscience Institute to facilitate human brain research. Biospecimens include human neurosurgical and postmortem brain tissue and body fluids. The NeuroBank Core also generates human postmortem tissue-derived fibroblasts for patient-specific cellular and tissue models, including neurotypical subjects (fetus and adults), and those for Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, schizophrenia, Huntington’s disease, and more. This biorepository allows investigators to connect with de-identified clinical records, gross and histopathological imaging, and associated big data. The Iowa NeuroBank Core also provides training, services, partnership, and novel instrumentation to equip investigators with access to new technologies, including the 10X Genomics Visium spatial transcriptomics and Nanostring nCounter services for multiplex analysis, which is a joint collaboration between the Iowa NeuroBank Core, the Iowa Institute of Human Genetics (IIHG) Genomics Division, and the Central Microscopy Research Facilities.