This page provides information about the hourly rate to perform MRI Research and also outlines the process for starting a new research project utilizing equipment managed by the MRI Research Facility.
The FY2016 internal scanner rate is $615/hour, and includes a technologist to run the scanner. Other supplies (e.g. contrast agents or any further manpower required) will incur additional fees. Scanner time is allocated in 15 minute increments, and is available Monday through Friday from 8:00am to 6:00pm. After-hours and weekend scanner time that requires a technologist is available as requested. Advance notice (preferably two weeks) is requested. Contact Marla Kleingartner and Autumn Craig for more information.
Budgeting for Research Scans
Research scans at The University of Iowa are not considered patient care costs. Research MRI scans are considered "other costs" and are subject to Facilities and Administrative (F&A) costs. An exception to this rule may include scans funded by an NIH contract whereby F&A costs are explicitly excluded. If you believe F&A should not be charged to your grant, consult with your departmental grant accountant.
- More information about patient care definitions can be found on the NIH webpage 19.2 Definitions: Research Patient Care Costs.
- Current F&A rates can be found at the Division of Sponsored Program's webpage Facilities & Administrative (F&A) Costs.
New Project Submission Resources
- Example Proposal
- Research Advisory Committee Meeting Dates/Board Members
- NIH Equipment Information (updated 12/14/2011)
Proposal Submission Guidelines
Meetings will occur every other Monday from 10:30am - 11:30am. Proposals must be submitted by 5pm the Wednesday before the meeting. The submission process is completely electronic and requires the submission of Microsoft Word or PDF files only. Projects to be considered need to perform the following steps:
- Consult with a Research Committee Full Board Member. A link to the list of committee members can be found above.
- Obtain a submission login and password by going to the MRI Research Login Request Page
- Prepare a proposal application in Microsoft Word or PDF format. You will upload your typed proposal to your electronic submission. In your typed application, include:
- Abstract (1/2 page)
- Background and significance of your proposal(1/2 page)
- Scanner and coils to be used. A list of available scanners and accompanying equipment can be found on our equipment page
- Required sequences (e.g. DTI, T1, T2, BOLD, EPI, PEPSI)
- Will sequence, coil or hardware development be required to implement the protocol?
- Will image analysis be required?
- Methods and approach (1 pages)
- Data analysis (1/2 page)
- If the proposal is currently unfunded, then provide information about potential funding sources, a plan, and timeline for seeking funding. Describe how this data will be helpful in acquiring funding (1/2 page).
- Once you have received your proposal submission login information, log in and complete the electronic submission form. Have the following information available:
- Primary Investigator contact information
- Any additional project personnel
- Status of funding, including an MFK (if available)
- Status of IRB Submission. Researchers of human studies must provide a stamped copy of the IRB Informed Consent document prior to requesting scanner time.
- Each research project proposal will be assigned to two members of the review committee. Ad-hoc members may be assigned to review proposals.
Gadolinium Usage Guidelines
The FDA released a new guidance on 9/9/2010 regarding the warnings and screening requirements for possible reduced kidney function and the use of gadolinium contrast for research studies http://www.fda.gov/Drugs/DrugSafety/ucm223966.htm?sms_ss=email. The MRI Research Center and IRB minimum recommendations for gadolinium usage are as follows:
- Screen patients prior to administration of gadolinium-based contrast agents to identify those with acute kidney injury or chronic, severe, kidney disease. If an MRI with gadolinium is performed solely for research purposes, the IRB is likely to require that renal function be specially tested (e.g. serum creatinine) prior to the MRI, as many patients with reduced kidney function will be asymptomatic and not aware of their level of kidney function. The minimum allowable GFR measurement for all subjects receiving contrast is 60.
- Use the clinical history to screen patients for features of acute kidney injury or risk factors for chronically reduced kidney function.
- Monitor for signs and symptoms of Nephrogenic Systemic Fibrosis after gadolinium-based contrast agents are administered to a patient suspected or known to have impaired elimination of the drug.
- Do not repeat administration of any gadolinium-based contrast agents during a single imaging session.
- Advise subjects with kidney disease to contact a healthcare professional if any of the following symptoms occurs after receiving a gadolinium-based contrast agents: burning, itching, swelling, scaling, hardening and tightening of the skin; red or dark patches on the skin; stiffness in joints with trouble moving, bending or straightening the arms, hands, legs or feet; pain in the hip bones or ribs; or muscle weakness.
- Record the specific gadolinium-based contrast agents and the dose administered to a patient.
- When administering gadolinium-based contrast agents, do not exceed the recommended dose. Prior to any re-administration, allow sufficient time for elimination of the gadolinium-based contrast agents from the body.
Once a project is submitted the following criteria will be used to determine the scientific ranking for the project:
- Feasibility of project
- Funding status/likelihood of funding
- Development required to implement project
- Availability of personnel and equipment
Once a scientific ranking has been determined, it will be translated into a priority for scan time allocation. This allocation will be assigned a project number that can be used to schedule time using the online scheduling system.
Scan time priorities:
- Standard Hours
- After Hours/Weekends
6-month project reports are required to keep a project active. These reports should include the following information:
- Number of subjects studied
- Status of data analysis
- Papers submitted based on data
- Grants submitted based on data
- No accrual in 12 months may terminate a protocol
- Scan priority reviewed at 6 month intervals
The MRI Research Center supports a limited number of pilot projects each year, totaling approximately 18% of research time utilization. Pilot projects are given a reduced scanner rate to facilitate data collection for inclusion in grant submissions. This time is typically given to projects that are currently unfunded and require "proof of concept" by means of MR images. To qualify for pilot time, a project must meet certain exclusionary conditions, including approval of pilot time by the MRI Research Advisory Committee. To find out about the possibility of obtaining pilot time for MR data collection, contact one of our full board members listed above.