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All Publications

Last updated 02/25/2021

Agostinelli, Lindsay

Agostinelli LJ, Mix MR, Hefti MM, Scammell TE, Bassuk AG. Input-output connections of LJA5 prodynorphin neurons. J Comp Neurol. 2020 Jun 30. doi: 10.1002/cne.24974. Epub ahead of print. PMID: 32602558.

Agostinelli LJ, Bassuk AG. Novel inhibitory brainstem neurons with selective projections to spinal lamina I reduces both pain and itch. J Comp Neurol. 2020 Nov 27. doi: 10.1002/cne.25076. Epub ahead of print. PMID: 33247430.

Arkee, Tina

Arkee T, Bishop GA. TRAF family molecules in T cells: Multiple receptors and functions. J Leukoc Biol. 2020 Jun;107(6):907-915. doi: 10.1002/JLB.2MR1119-397R. Epub 2019 Nov 21. Review. PubMed PMID: 31749173; PubMed Central PMCID: PMC7239704.

Rogers KJ, Shtanko O, Stunz LL, Mallinger LN, Arkee T, Schmidt ME, Bohan D, Brunton B, White JM, Varga SM, Butler NS, Bishop GA, Maury W. Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection. J Leukoc Biol. 2020 May 22;. doi: 10.1002/JLB.4HI0420-285RR. [Epub ahead of print] PubMed PMID: 32441445.

Boland, Lauren

Starks RD, Beyer AM, Guo DF, Boland L, Zhang Q, Sheffield VC, Rahmouni K. Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins. PLoS Genet. 2015 Jun 23;11(6):e1005311. doi: 10.1371/journal.pgen.1005311. eCollection 2015 Jun. PubMed PMID: 26103456; PubMed Central PMCID: PMC4478011.

Boland L, Burand AJ, Brown AJ, Boyt D, Lira VA, Ankrum JA. IFN-γ and TNF-α Pre-licensing Protects Mesenchymal Stromal Cells from the Pro-inflammatory Effects of Palmitate. Mol Ther. 2018 Mar 7;26(3):860-873. doi: 10.1016/j.ymthe.2017.12.013. Epub 2017 Dec 19. PubMed PMID: 29352647; PubMed Central PMCID: PMC5910660.

Burand AJ Jr, Boland L, Brown AJ, Ankrum JA. A Low-Cost Technique for Intraoperative Imaging of Cell Delivery and Retention in a Model of Delayed Wound Healing. Adv Wound Care (New Rochelle). 2017 Dec 1;6(12):413-424. doi: 10.1089/wound.2017.0751. PubMed PMID: 29279805; PubMed Central PMCID: PMC5734161.

Boland LK, Burand AJ, Boyt DT, Dobroski H, Di L, Liszewski JN, Schrodt MV, Frazer MK, Santillan DA, Ankrum JA. Nature vs. Nurture: Defining the Effects of Mesenchymal Stromal Cell Isolation and Culture Conditions on Resiliency to Palmitate Challenge. Front Immunol. 2019 May 10;10:1080. doi: 10.3389/fimmu.2019.01080. eCollection 2019. PubMed PMID: 31134100; PubMed Central PMCID: PMC6523025.

Burand AJ Jr, Di L, Boland LK, Boyt DT, Schrodt MV, Santillan DA, Ankrum JA.  Aggregation of Human Mesenchymal Stromal Cells Eliminates Their Ability to Suppress Human T Cells. Front Immunol. 2020;11:143. doi: 10.3389/fimmu.2020.00143. eCollection 2020. PubMed PMID: 32158443; PubMed Central PMCID: PMC7052295.

Markan KR, Boland LK, King-McAlpin AQ, Claflin KE, Leaman MP, Kemerling MK, Stonewall MM, Amendt BA, Ankrum JA, Potthoff MJ. Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo. Mol Metab. 2020 Feb 18;36:100965. doi: 10.1016/j.molmet.2020.02.008. [Epub ahead of print] PubMed PMID: 32240964; PubMed Central PMCID: PMC7115112.

Boyt DT, Boland LK, Burand AJ Jr, Brown AJ, Ankrum JA. Dose and duration of interferon γ pre-licensing interact with donor characteristics to influence the expression and function of indoleamine-2,3-dioxygenase in mesenchymal stromal cells. J R Soc Interface. 2020 Jun;17(167):20190815. doi: 10.1098/rsif.2019.0815. Epub 2020 Jun 17. PubMed PMID: 32546114; PubMed Central PMCID: PMC7328385.

Gramlich OW, Brown AJ, Godwin CR, Chimenti MS, Boland LK, Ankrum JA, Kardon RH. Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis. Transl Vis Sci Technol. 2020 Jul 10;9(8):16. doi: 10.1167/tvst.9.8.16. PMID: 32855863; PMCID: PMC7422913.

Markan KR, Boland LK, King-McAlpin AQ, Claflin KE, Leaman MP, Kemerling MK, Stonewall MM, Amendt BA, Ankrum JA, Potthoff MJ. Corrigendum to "Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo" [Molecular Metabolism 36 (2020) 100965]. Mol Metab. 2020 Dec 24:101148. doi: 10.1016/j.molmet.2020.101148. Epub ahead of print. Erratum for: Mol Metab. 2020 Jun;36:100965. PMID: 33358927.

Bowen, Jayden

Borbón TY, Scorza BM, Clay GM, Lima Nobre de Queiroz F, Sariol AJ, Bowen JL, Chen Y, Zhanbolat B, Parlet CP, Valadares DG, Cassel SL, Nauseef WM, Horswill AR, Sutterwala FS, Wilson ME. Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A. PLoS Negl Trop Dis. 2019 May;13(5):e0007247. doi: 10.1371/journal.pntd.0007247. eCollection 2019 May. PubMed PMID: 31107882; PubMed Central PMCID: PMC6527190.

Brueggeman, Leo

Michaelson JJ, Shin MK, Koh JY, Brueggeman L, Zhang A, Katzman A, McDaniel L, Fang M, Pufall M, Pieper AA. Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes. Biol Psychiatry. 2017 Aug 1;82(3):213-223. doi: 10.1016/j.biopsych.2017.03.021. Epub 2017 Apr 6. PubMed PMID: 28499489; PubMed Central PMCID: PMC6901278.

Brueggeman L, Sturgeon ML, Martin RM, Grossbach AJ, Nagahama Y, Zhang A, Howard MA 3rd, Kawasaki H, Wu S, Cornell RA, Michaelson JJ, Bassuk AG. Drug repositioning in epilepsy reveals novel antiseizure candidates. Ann Clin Transl Neurol. 2019 Feb;6(2):295-309. doi: 10.1002/acn3.703. eCollection 2019 Feb. PubMed PMID: 30847362; PubMed Central PMCID: PMC6389756.

Feliciano P, Zhou X, Astrovskaya I, Turner TN, Wang T, Brueggeman L, Barnard R, Hsieh A, Snyder LG, Muzny DM, Sabo A; SPARK Consortium, Gibbs RA, Eichler EE, O'Roak BJ, Michaelson JJ, Volfovsky N, Shen Y, Chung WK. Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. NPJ Genom Med. 2019 Aug 23;4:19. doi: 10.1038/s41525-019-0093-8. eCollection 2019. PubMed PMID: 31452935; PubMed Central PMCID: PMC6707204.

Brueggeman L, Koomar T, Michaelson JJ. Author Correction: Forecasting risk gene discovery in autism with machine learning and genome-scale data. Sci Rep. 2020 Nov 26;10(1):20994. doi: 10.1038/s41598-020-77832-2. Erratum for: Sci Rep. 2020 Mar 12;10(1):4569. PMID: 33244169; PMCID: PMC7691369.

Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z; Eating Disorders Working Group of the Psychiatric Genomics Consortium; International Headache Genetics Consortium; 23andMe Research Team, Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF. Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. Nat Genet. 2020 Apr 27. doi: 10.1038/s41588-020-0610-9. [Epub ahead of print] PubMed PMID: 32341526.

Buchanan, Jane

Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB. Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis. Cell Rep. 2019 Sep 3;28(10):2608-2619.e6. doi: 10.1016/j.celrep.2019.07.098. PubMed PMID: 31484072; PubMed Central PMCID: PMC6746334.

Burghardt, Elliot

Evans LP, Boehme N, Wu S, Burghardt EL, Akurathi A, Todd BP, Newell EA, Ferguson PJ, Mahajan VB, Dutca LM, Harper MM, Bassuk AG. Sex Does Not Influence Visual Outcomes After Blast-Mediated Traumatic Brain Injury but IL-1 Pathway Mutations Confer Partial Rescue. Invest Ophthalmol Vis Sci. 2020 Oct 1;61(12):7. doi: 10.1167/iovs.61.12.7. PMID: 33030508.

Evans, Lucy

Evans LP, Newell EA, Mahajan M, Tsang SH, Ferguson PJ, Mahoney J, Hue CD, Vogel EW 3rd, Morrison B 3rd, Arancio O, Nichols R, Bassuk AG, Mahajan VB. Acute vitreoretinal trauma and inflammation after traumatic brain injury in mice. Ann Clin Transl Neurol. 2018 Mar;5(3):240-251. doi: 10.1002/acn3.523. eCollection 2018 Mar. PubMed PMID: 29560370; PubMed Central PMCID: PMC5846452.

Almeida DRP, Chin EK, Arjmand P, Velez G, Evans LP, Mahajan VB. Fibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy. Ophthalmic Surg Lasers Imaging Retina. 2018 Dec 1;49(12):e271-e277. doi: 10.3928/23258160-20181203-18. PubMed PMID: 30566713.

Harper MM, Woll AW, Evans LP, Delcau M, Akurathi A, Hedberg-Buenz A, Soukup DA, Boehme N, Hefti MM, Dutca LM, Anderson MG, Bassuk AG. Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury. Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4159-4170. doi: 10.1167/iovs.19-27565. PubMed PMID: 31598627; PubMed Central PMCID: PMC6785841.

Newell EA, Todd BP, Luo Z, Evans LP, Ferguson PJ, Bassuk AG. A Mouse Model for Juvenile, Lateral Fluid Percussion Brain Injury Reveals Sex-Dependent Differences in Neuroinflammation and Functional Recovery. J Neurotrauma. 2020 Feb 15;37(4):635-646. doi: 10.1089/neu.2019.6675. Epub 2019 Dec 5. PubMed PMID: 31621484; PubMed Central PMCID: PMC7045348.

Wert KJ, Velez G, Kanchustambham VL, Shankar V, Evans LP, Sengillo JD, Zare RN, Bassuk AG, Tsang SH, Mahajan VB. Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration. EBioMedicine. 2020 Feb;52:102636. doi: 10.1016/j.ebiom.2020.102636. Epub 2020 Feb 3. PubMed PMID: 32028070; PubMed Central PMCID: PMC7005447.

Harper MM, Rudd D, Meyer KJ, Kanthasamy AG, Anantharam V, Pieper AA, Vázquez-Rosa E, Shin MK, Chaubey K, Koh Y, Evans LP, Bassuk AG, Anderson MG, Dutca L, Kudva IT, John M. Identification of chronic brain protein changes and protein targets of serum auto-antibodies after blast-mediated traumatic brain injury. Heliyon. 2020 Feb;6(2):e03374. doi: 10.1016/j.heliyon.2020.e03374. eCollection 2020 Feb. PubMed PMID: 32099918; PubMed Central PMCID: PMC7029173.

Evans LP, Woll AW, Wu S, Todd BP, Hehr N, Hedberg-Buenz A, Anderson MG, Newell EA, Ferguson PJ, Mahajan VB, Harper MM, Bassuk AG. Modulation of Post-Traumatic Immune Response Using the IL-1 Receptor Antagonist Anakinra for Improved Visual Outcomes. J Neurotrauma. 2020 Jun 15;37(12):1463-1480. doi: 10.1089/neu.2019.6725. Epub 2020 Mar 16. PubMed PMID: 32056479; PubMed Central PMCID: PMC7249480.

Evans LP, Boehme N, Wu S, Burghardt EL, Akurathi A, Todd BP, Newell EA, Ferguson PJ, Mahajan VB, Dutca LM, Harper MM, Bassuk AG. Sex Does Not Influence Visual Outcomes After Blast-Mediated Traumatic Brain Injury but IL-1 Pathway Mutations Confer Partial Rescue. Invest Ophthalmol Vis Sci. 2020 Oct 1;61(12):7. doi: 10.1167/iovs.61.12.7. PMID: 33030508.

Gildenberg, Melissa

Boehm EM, Gildenberg MS, Washington MT. The Many Roles of PCNA in Eukaryotic DNA Replication. Enzymes. 2016;39:231-54. doi: 10.1016/bs.enz.2016.03.003. Epub 2016 Apr 19. Review. PubMed PMID: 27241932; PubMed Central PMCID: PMC4890617.

Powers KT, Gildenberg MS, Washington MT. Modeling Conformationally Flexible Proteins With X-ray Scattering and Molecular Simulations. Comput Struct Biotechnol J. 2019;17:570-578. doi: 10.1016/j.csbj.2019.04.011. eCollection 2019. Review. PubMed PMID: 31073392; PubMed Central PMCID: PMC6495069.

Gildenberg MS, Washington MT. Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods. PLoS One. 2019;14(10):e0223875. doi: 10.1371/journal.pone.0223875. eCollection 2019. PubMed PMID: 31626633; PubMed Central PMCID: PMC6799953.

Ripley BM, Gildenberg MS, Washington MT. Control of DNA Damage Bypass by Ubiquitylation of PCNA. Genes (Basel). 2020 Jan 29;11(2). doi: 10.3390/genes11020138. Review. PubMed PMID: 32013080; PubMed Central PMCID: PMC7074500.

Washington MT, Gildenberg MS. Structure of DNA polymerase ζ: capturing the getaway driver. Nat Struct Mol Biol. 2020 Aug 25. doi: 10.1038/s41594-020-0502-9. Epub ahead of print. PMID: 32843752.

Grady, Fillan

Cox AJ, Grady F, Velez G, Mahajan VB, Ferguson PJ, Kitchen A, Darbro BW, Bassuk AG. In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth. Genet Res (Camb). 2019 Jun 13;101:e8. doi: 10.1017/S0016672319000065. PubMed PMID: 31190668; PubMed Central PMCID: PMC7045018.

Grady F, Peltekian L, Iverson G, Geerling JC. Direct Parabrachial-Cortical Connectivity. Cereb Cortex. 2020 Jul 30;30(9):4811-4833. doi: 10.1093/cercor/bhaa072. PubMed PMID: 32383444; PubMed Central PMCID: PMC7391272.

Greiner, Alexander

London B, Greiner AM, Mehdi H, Gutmann R. IDENTIFYING NEW SUDDEN DEATH GENES. Trans Am Clin Climatol Assoc. 2018;129:183-184. PubMed PMID: 30166713; PubMed Central PMCID: PMC6116611.

Greiner AM, Kaldjian LC. Rethinking medical oaths using the Physician Charter and ethical virtues. Med Educ. 2018 Aug;52(8):826-837. doi: 10.1111/medu.13581. Epub 2018 Apr 27. PubMed PMID: 29700846.

London B, Greiner AM, Mehdi H, Gutmann R. Identifying New Sudden Death Genes. Trans Am Clin Climatol Assoc. 2018;129:183-184. PMID: 30166713; PMCID: PMC6116611.

Matasic DS, Yoon JY, McLendon JM, Mehdi H, Schmidt MS, Greiner AM, Quinones P, Morgan GM, Boudreau RL, Irani K, Brenner C, London B. Modulation of the cardiac sodium channel NaV1.5 peak and late currents by NAD+ precursors. J Mol Cell Cardiol. 2020 Apr;141:70-81. doi: 10.1016/j.yjmcc.2020.01.013. Epub 2020 Mar 21. PubMed PMID: 32209328; PubMed Central PMCID: PMC7234910.

Grunewald, Matthew

Ahmer J, Fehr AR, Grunewald M, Smith EC, Denison MR, Perlman S. In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins. MBio. 2017 Jan 31;8(1). doi: 10.1128/mBio.02320-16. PubMed PMID: 28143984; PubMed Central PMCID: PMC5285509.

Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):E5444-E5453. doi: 10.1073/pnas.1704099114. Epub 2017 Jun 19. PubMed PMID: 28630327; PubMed Central PMCID: PMC5502630.

Grunewald ME, Fehr AR, Athmer J, Perlman S. The coronavirus nucleocapsid protein is ADP-ribosylated. Virology. 2018 Apr;517:62-68. doi: 10.1016/j.virol.2017.11.020. Epub 2017 Dec 1. PubMed PMID: 29199039; PubMed Central PMCID: PMC5871557.

Athmer J, Fehr AR, Grunewald ME, Qu W, Wheeler DL, Graepel KW, Channappanavar R, Sekine A, Aldabeeb DS, Gale M Jr, Denison MR, Perlman S. Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses. Mbio. 2018 May 1;9(3). Doi: 10.1128/mBio.00272-18. PubMed PMID: 29717007; PubMed Central PMCID: PMC5930304.

Grunewald ME, Chen Y, Kuny C, Maejima T, Lease R, Ferraris D, Aikawa M, Sullivan CS, Perlman S, Fehr AR. The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression. PLoS Pathog. 2019 May;15(5):e1007756. doi: 10.1371/journal.ppat.1007756. eCollection 2019 May. PubMed PMID: 31095648; PubMed Central PMCID: PMC6521996.

Grunewald ME, Shaban MG, Mackin SR, Fehr AR, Perlman S. Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression. J Virol. 2020 Jan 17;94(3). doi: 10.1128/JVI.01743-19. Print 2020 Jan 17. PubMed PMID: 31694960; PubMed Central PMCID: PMC7000979.

Wang Y, Grunewald M, Perlman S. Coronaviruses: An Updated Overview of Their Replication and Pathogenesis. Methods Mol Biol. 2020;2203:1-29. doi: 10.1007/978-1-0716-0900-2_1. Review.  PMID: 32833200.

Gutierrez, Wade

Kruspe S, Dickey DD, Urak KT, Blanco GN, Miller MJ, Clark KC, Burghardt E, Gutierrez WR, Phadke SD, Kamboj S, Ginader T, Smith BJ, Grimm SK, Schappet J, Ozer H, Thomas A, McNamara JO 2nd, Chan CH, Giangrande PH. Rapid and Sensitive Detection of Breast Cancer Cells in Patient Blood with Nuclease-Activated Probe Technology. Mol Ther Nucleic Acids. 2017 Sep 15;8:542-557. doi: 10.1016/j.omtn.2017.08.004. Epub 2017 Aug 12. PMCID: PMC5577414.

Kerov V, Laird JG, Joiner ML, Knecht S, Soh D, Hagen J, Gardner SH, Gutierrez W, Yoshimatsu T, Bhattarai S, Puthussery T, Artemyev NO, Drack AV, Wong RO, Baker SA, Lee A. α(2)δ-4 Is Required for the Molecular and Structural Organization of Rod and Cone Photoreceptor Synapses. J Neurosci. 2018 Jul 4;38(27):6145-6160. doi: 10.1523/JNEUROSCI.3818-16.2018. Epub 2018 Jun 6. PMCID: PMC6031576.

Urak KT, Blanco GN, Shubham S, Lin LH, Dassie JP, Thiel WH, Chen Y, Sonkar VK, Lei B, Murthy S, Gutierrez WR, Wilson ME, Stiber JA, Klesney-Tait J, Dayal S, Miller FJ Jr, Giangrande PH. RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome. Nat Commun. 2019 Jan 10;10(1):116. doi: 10.1038/s41467-018-08030-y. PubMed PMID: 30631065; PMCID: PMC6328615.

Scherer A, Stephens VR, McGivney GR, Gutierrez WR, Laverty EA, Knepper-Adrian V, Dodd RD. Distinct Tumor Microenvironments Are a Defining Feature of Strain-Specific CRISPR/Cas9-Induced MPNSTs. Genes (Basel). 2020 May 23;11(5). doi: 10.3390/genes11050583. PubMed PMID: 32456131; PubMed Central PMCID: PMC7288323.

Dodd RD, Scherer A, Huang W, McGivney GR, Gutierrez WR, Laverty E, Ashcraft KA, Stephens VR, Yousefpour P, Saha S, Knepper-Adrian VL, Floyd W, Chen M, Ma Y, Mastria EM, Cardona DM, Eward WC, Chilkoti A, Kirsch DG. Tumor subtype determines therapeutic response to chimeric polypeptide nanoparticle-based chemotherapy in Pten-deleted mouse models of sarcoma. Clin Cancer Res. 2020 Jul 27:clincanres.2597.2019. doi: 10.1158/1078-0432.CCR-19-2597. Epub ahead of print. PMID: 32718998.

Yong C, Moose DL, Bannick N, Gutierrez WR, Vanneste M, Svensson R, Breheny P, Brown JA, Dodd RD, Cohen MB, Henry MD. Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging. PLoS One. 2020;15(9):e0232807. doi: 10.1371/journal.pone.0232807. eCollection 2020. PubMed PMID: 32986721; PubMed Central PMCID: PMC7521703.

Gutierrez WR, Scherer A, McGivney GR, Brockman QR, Knepper-Adrian V, Laverty EA, Roughton GA, Dodd RD. Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models. Sci Rep. 2021 Jan 13;11(1):1098. doi: 10.1038/s41598-020-80216-1. PMID: 33441747; PMCID: PMC7806664.

Huang, Sunny

Carter CS*, Huang SC*, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton AO Jr, Guo DF, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. Cell Metab. 2020 Oct 6;32(4):561-574.e7. doi: 10.1016/j.cmet.2020.09.012. PMID: 33027675 [*Co-first authors]

Hubert, Kelly (Falls)

Hagen J, Muniz VP, Falls KC, Reed SM, Taghiyev AF, Quelle FW, Gourronc FA, Klingelhutz AJ, Major HJ, Askeland RW, Sherman SK, O'Dorisio TM, Bellizzi AM, Howe JR, Darbro BW, Quelle DE. RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner. Cancer Res. 2014 Nov 15;74(22):6661-70. doi: 10.1158/0008-5472.CAN-13-3742. Epub 2014 Oct 1. PubMed PMID: 25273089; PubMed Central PMCID: PMC4233153.

Sciegienka SJ, Solst SR, Falls KC, Schoenfeld JD, Klinger AR, Ross NL, Rodman SN, Spitz DR, Fath MA. D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H2O2-mediated oxidative stress. Free Radic Biol Med. 2017 Jul;108:354-361. doi: 10.1016/j.freeradbiomed.2017.04.001. Epub 2017 Apr 5. PubMed PMID: 28389407; PubMed Central PMCID: PMC5495544.

Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biol. 2018 Apr;14:82-87. doi: 10.1016/j.redox.2017.08.017. Epub 2017 Aug 26. PubMed PMID: 28886484; PubMed Central PMCID: PMC5591450.

Falls KC, Sharma RA, Lawrence YR, Amos RA, Advani SJ, Ahmed MM, Vikram B, Coleman CN, Prasanna PG. Radiation-Drug Combinations to Improve Clinical Outcomes and Reduce Normal Tissue Toxicities: Current Challenges and New Approaches: Report of the Symposium Held at the 63rd Annual Meeting of the Radiation Research Society, 15-18 October 2017; Cancun, Mexico. Radiat Res. 2018 Oct;190(4):350-360. doi: 10.1667/RR15121.1. PubMed PMID: 30280985; PubMed Central PMCID: PMC6322391.

Heer CD, Davis AB, Riffe DB, Wagner BA, Falls KC, Allen BG, Buettner GR, Beardsley RA, Riley DP, Spitz DR. Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner. Antioxidants (Basel). 2018 Jan 19;7(1). doi: 10.3390/antiox7010018. PubMed PMID: 29351198; PubMed Central PMCID: PMC5789328.

Brandt KE, Falls KC, Schoenfeld JD, Rodman SN 3rd, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Corrigendum to: Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells [Redox Biol. (2018) 82-87]. Redox Biol. 2020 Jan;28:100935. doi: 10.1016/j.redox.2018.06.001. Epub 2018 Jun 8. PubMed PMID: 29891355; PubMed Central PMCID: PMC6920117.

Gibson AR, O'Leary BR, Du J, Sarsour EH, Kalen AL, Wagner BA, Stolwijk JM, Falls-Hubert KC, Alexander MS, Carroll RS, Spitz DR, Buettner GR, Goswami PC, Cullen JJ. Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity. Cancer Res. 2020 Apr 1;80(7):1401-1413. doi: 10.1158/0008-5472.CAN-19-3094. Epub 2020 Feb 10. PubMed PMID: 32041838; PubMed Central PMCID: PMC7127976.

Carter CS, Huang SC, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton AO Jr, Guo DF, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. Cell Metab. 2020 Oct 6;32(4):561-574.e7. doi: 10.1016/j.cmet.2020.09.012. PMID: 33027675.

Kelley, Ryan

Parker KL, Kim YC, Kelley RM, Nessler AJ, Chen KH, Muller-Ewald VA, Andreasen NC, Narayanan NS. Delta-frequency stimulation of cerebellar projections can compensate for schizophrenia-related medial frontal dysfunction. Mol Psychiatry. 2017 May;22(5):647-655. doi: 10.1038/mp.2017.50. Epub 2017 Mar 28. PubMed PMID: 28348382; PubMed Central PMCID: PMC5873945.

Emmons EB, Ruggiero RN, Kelley RM, Parker KL, Narayanan NS. Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents. Front Psychol. 2016;7:459. doi: 10.3389/fpsyg.2016.00459. eCollection 2016. PubMed PMID: 27092091; PubMed Central PMCID: PMC4820903.

Kingyon J, Behroozmand R, Kelley R, Oya H, Kawasaki H, Narayanan NS, Greenlee JD. Corrigendum to "High-gamma band fronto-temporal coherence as a measure of functional connectivity in speech motor control" [Neuroscience 305 (2015) 15-25]. Neuroscience. 2016 Oct 29;335:242. doi: 10.1016/j.neuroscience.2016.07.019. Epub 2016 Jul 20. PubMed PMID: 27448528.

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Markan KR, Boland LK, King-McAlpin AQ, Claflin KE, Leaman MP, Kemerling MK, Stonewall MM, Amendt BA, Ankrum JA, Potthoff MJ. Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo. Mol Metab. 2020 Feb 18;36:100965. doi: 10.1016/j.molmet.2020.02.008. [Epub ahead of print] PubMed PMID: 32240964; PubMed Central PMCID: PMC7115112.

Gansemer ER, McCommis KS, Martino M, King-McAlpin AQ, Potthoff MJ, Finck BN, Taylor EB, Rutkowski DT. NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis. iScience. 2020 May 22;23(5):101116. doi: 10.1016/j.isci.2020.101116. Epub 2020 Apr 29. PubMed PMID: 32417402; PubMed Central PMCID: PMC7254477.

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Martin MD, Jensen IJ, Ishizuka AS, Lefebvre M, Shan Q, Xue HH, Harty JT, Seder RA, Badovinac VP. Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells. J Clin Invest. 2019 Jun 20;129(9):3894-3908. doi: 10.1172/JCI124443. PubMed PMID: 31219804; PubMed Central PMCID: PMC6715387.

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Jensen IJ, McGonagill PW, Lefebvre MN, Griffith TS, Harty JT, Badovinac VP. Worry and FRET: ROS Production Leads to Fluorochrome Tandem Degradation and impairs Interpretation of Flow Cytometric Results. Immunity. 2020 Mar 17;52(3):419-421. doi: 10.1016/j.immuni.2020.02.003. PubMed PMID: 32187510; PubMed Central PMCID: PMC7251922.

Lefebvre MN, Harty JT. γδ T cells burst malaria's bubble. Nat Immunol. 2021 Feb 5. doi: 10.1038/s41590-021-00879-4. Epub ahead of print. PMID: 33547458.

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Cooney AL, Singh BK, Loza LM, Thornell IM, Hippee CE, Powers LS, Ostedgaard LS, Meyerholz DK, Wohlford-Lenane C, Stoltz DA, B McCray P Jr, Sinn PL. Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus. Nucleic Acids Res. 2018 Oct 12;46(18):9591-9600. doi: 10.1093/nar/gky773. PubMed PMID: 30165523; PubMed Central PMCID: PMC6182177

Marquez Loza LI, Yuen EC, McCray PB Jr. Lentiviral Vectors for the Treatment and Prevention of Cystic Fibrosis Lung Disease. Genes (Basel). 2019 Mar 14;10(3). Doi: 10.3390/genes10030218. Review. PubMed PMID: 30875857; PubMed Central PMCID: PMC6471883.

Matasic, Daniel

Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. PubMed PMID: 28191886; PubMed Central PMCID: PMC6218171.

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Matasic DS, Yoon JY, McLendon JM, Mehdi H, Schmidt MS, Greiner AM, Quinones P, Morgan GM, Boudreau RL, Irani K, Brenner C, London B. Modulation of the cardiac sodium channel NaV1.5 peak and late currents by NAD+ precursors. J Mol Cell Cardiol. 2020 Apr;141:70-81. doi: 10.1016/j.yjmcc.2020.01.013. Epub 2020 Mar 21. PubMed PMID: 32209328; PubMed Central PMCID: PMC7234910.

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Miller, Matthew

Giacalone JC, Miller MJ, Workalemahu G, Reutzel AJ, Ochoa D, Whitmore SS, Stone EM, Tucker BA, Mullins RF. Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter. Microvasc Res. 2019 May;123:50-57. doi: 10.1016/j.mvr.2018.12.002. Epub 2018 Dec 18. PubMed PMID: 30571950; PubMed Central PMCID: PMC7401191.

Carter CS, Huang SC, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton AO Jr, Guo DF, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. Cell Metab. 2020 Oct 6;32(4):561-574.e7. doi: 10.1016/j.cmet.2020.09.012. PMID: 33027675.

Mix, Madison

Agostinelli LJ, Mix MR, Hefti MM, Scammell TE, Bassuk AG. Input-output connections of LJA5 prodynorphin neurons. J Comp Neurol. 2020 Jun 30. doi: 10.1002/cne.24974. Epub ahead of print. PMID: 32602558.

Mullin, Nathaniel

Thompson JR, Worthington KS, Green BJ, Mullin NK, Jiao C, Kaalberg EE, Wiley LA, Han IC, Russell SR, Sohn EH, Guymon CA, Mullins RF, Stone EM, Tucker BA. Two-photon polymerized poly(caprolactone) retinal cell delivery scaffolds and their systemic and retinal biocompatibility. Acta Biomater. 2019 Aug;94:204-218. doi: 10.1016/j.actbio.2019.04.057. Epub 2019 May 3. PubMed PMID: 31055121; PubMed Central PMCID: PMC6659122.

Voigt AP, Mulfaul K, Mullin NK, Flamme-Wiese MJ, Giacalone JC, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24100-24107. doi: 10.1073/pnas.1914143116. Epub 2019 Nov 11. PubMed PMID: 31712411; PubMed Central PMCID: PMC6883845.

Mullin NK, Voigt AP, Cooke JA, Bohrer LR, Burnight ER, Stone EM, Mullins RF, Tucker BA. Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease. Prog Retin Eye Res. 2020 Oct 29:100918. doi: 10.1016/j.preteyeres.2020.100918. Epub ahead of print. PMID: 33130253.

Voigt AP, Mullin NK, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell RNA sequencing in vision research: Insights into human retinal health and disease. Prog Retin Eye Res. 2020 Dec 28:100934. doi: 10.1016/j.preteyeres.2020.100934. Epub ahead of print. PMID: 33383180.

Pak, Thomas

Weihbrecht K, Goar WA, Pak T, Garrison JE, DeLuca AP, Stone EM, Scheetz TE, Sheffield VC. Keeping an Eye on Bardet-Biedl Syndrome: A Comprehensive Review of the Role of Bardet-Biedl Syndrome Genes in the Eye. Med Res Arch. 2017 Sep;5(9). doi: 10.18103/mra.v5i9.1526. Epub 2017 Sep 18. PubMed PMID: 29457131; PubMed Central PMCID: PMC5814251.

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Rogers, Kai

Rhein BA, Powers LS, Rogers K, Anantpadma M, Singh BK, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey RA, Monick MM, Maury W. Interferon-γ Inhibits Ebola Virus Infection. PLoS Pathog. 2015;11(11):e1005263. doi: 10.1371/journal.ppat.1005263. eCollection 2015. PubMed PMID: 26562011; PubMed Central PMCID: PMC4643030.

Brouillette RB, Phillips EK, Patel R, Mahauad-Fernandez W, Moller-Tank S, Rogers KJ, Dillard JA, Cooney AL, Martinez-Sobrido L, Okeoma C, Maury W. TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus. J Virol. 2018 Aug 15;92(16). doi: 10.1128/JVI.00093-18. Print 2018 Aug 15. PubMed PMID: 29875238; PubMed Central PMCID: PMC6069209.

Rogers KJ, Maury W. The role of mononuclear phagocytes in Ebola virus infection. J Leukoc Biol. 2018 Oct;104(4):717-727. doi: 10.1002/JLB.4RI0518-183R. Epub 2018 Aug 10. Review. PMID: 30095866.

Brunton B, Rogers K, Phillips EK, Brouillette RB, Bouls R, Butler NS, Maury W. TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis. PLoS Negl Trop Dis. 2019 Jun;13(6):e0006983. doi: 10.1371/journal.pntd.0006983. eCollection 2019 Jun. PubMed PMID: 31242184.

Rogers KJ, Brunton B, Mallinger L, Bohan D, Sevcik KM, Chen J, Ruggio N, Maury W. IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infection. PLoS Negl Trop Dis. 2019 Dec 11;13(12):e0007819. doi: 10.1371/journal.pntd.0007819. eCollection 2019 Dec. PubMed PMID: 31825972.

Rogers KJ, Jones-Burrage S, Maury W, Mukhopadhyay S. TF protein of Sindbis virus antagonizes host type I interferon responses in a palmitoylation-dependent manner. Virology. 2020 Mar;542:63-70. doi: 10.1016/j.virol.2020.01.001. Epub 2020 Jan 7. PubMed PMID: 32056669.

Rogers KJ, Shtanko O, Vijay R, Mallinger LN, Joyner CJ, Galinski MR, Butler NS, Maury W. Acute Plasmodium Infection Promotes Interferon-Gamma-Dependent Resistance to Ebola Virus Infection. Cell Rep. 2020 Mar 24;30(12):4041-4051.e4. doi: 10.1016/j.celrep.2020.02.104. PubMed PMID: 32209467.

Vijay R, Guthmiller JJ, Sturtz AJ, Surette FA, Rogers KJ, Sompallae RR, Li F, Pope RL, Chan JA, de Labastida Rivera F, Andrew D, Webb L, Maury WJ, Xue HH, Engwerda CR, McCarthy JS, Boyle MJ, Butler NS. Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria. Nat Immunol. 2020 Jul;21(7):790-801. doi: 10.1038/s41590-020-0678-5. Epub 2020 May 18. PubMed PMID: 32424361; PubMed Central PMCID: PMC7316608.

Rogers KJ, Shtanko O, Stunz LL, Mallinger LN, Arkee T, Schmidt ME, Bohan D, Brunton B, White JM, Varga SM, Butler NS, Bishop GA, Maury W. Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection. J Leukoc Biol. 2020 May 22;. doi: 10.1002/JLB.4HI0420-285RR. [Epub ahead of print] PubMed PMID: 32441445.

Romano Ibarra, Guillermo

Rehman T, Thornell IM, Pezzulo AA, Thurman AL, Romano Ibarra GS, Karp PH, Tan P, Duffey ME, Welsh MJ. TNFα and IL-17 Alkalinize Airway Surface Liquid through CFTR and Pendrin. Am J Physiol Cell Physiol. 2020 May 20;. doi: 10.1152/ajpcell.00112.2020. [Epub ahead of print] PubMed PMID: 32432926.

Ostedgaard LS, Price MP, Whitworth KM, Abou Alaiwa MH, Fischer AJ, Warrier A, Samuel M, Spate LD, Allen PD, Hilkin BM, Romano Ibarra GS, Ortiz Bezara ME, Goodell BJ, Mather SE, Powers LS, Stroik MR, Gansemer ND, Hippee CE, Zarei K, Goeken JA, Businga TR, Hoffman EA, Meyerholz DK, Prather RS, Stoltz DA, Welsh MJ. Lack of airway submucosal glands impairs respiratory host defenses. Elife. 2020 Oct 7;9:e59653. doi: 10.7554/eLife.59653. PMID: 33026343; PMCID: PMC7541087.

Sabree, Shakoora

Sabree S, Berg D, Sato M. Treatment of a pediatric patient with MET-amplified signet ring cell adenocarcinoma of the stomach with crizotinib. Pediatr Blood Cancer. 2018 Jun;65(6):e26984. doi: 10.1002/pbc.26984. Epub 2018 Jan 30. PubMed PMID: 29380521.

Sandouk, Aline

Zhang MS, Sandouk A, Houtman JC. Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics. Sci Rep. 2016 Jul 26;6:30225. doi: 10.1038/srep30225. PubMed PMID: 27456316; PubMed Central PMCID: PMC4960522.

Swanson, Morgan (Bobb)

Lee S, Harland KK, Swanson MB, Lawson S, Dahlstrom E, Clemson L, Himadi E. Safety of reassessment-and-release practice for mental health patients boarded in the emergency department. Am J Emerg Med. 2018 Nov;36(11):1967-1974. doi: 10.1016/j.ajem.2018.02.026. Epub 2018 Feb 27. PubMed PMID: 29525480.

Vakkalanka JP, Harland KK, Swanson MB, Mohr NM. Clinical and epidemiological variability in severe sepsis: an ecological study. J Epidemiol Community Health. 2018 Aug;72(8):741-745. doi: 10.1136/jech-2018-210501. Epub 2018 Apr 10. PubMed PMID: 29636401.

Friederich A, Martin N, Swanson MB, Faine BA, Mohr NM. Normal Saline Solution and Lactated Ringer's Solution Have a Similar Effect on Quality of Recovery: A Randomized Controlled Trial. Ann Emerg Med. 2019 Feb;73(2):160-169. doi: 10.1016/j.annemergmed.2018.07.007. Epub 2018 Aug 23. PubMed PMID: 30146446; PubMed Central PMCID: PMC6340785.

Lee S, Hardy C, Swanson MB, Harland K, Ahmed A, Ballas Z. Preliminary findings from a concise emergency department model to predict anaphylaxis and develop a clinical decision support tool. J Allergy Clin Immunol Pract. 2019 Apr 9. pii: S2213-2198(19)30373-3. doi: 10.1016/j.jaip.2019.04.002. [Epub ahead of print] PubMed PMID: 30974208

Negaard M, Vakkalanka P, Whipple MT, Hogrefe C, Swanson MB, Harland KK, Mathiasen R, Van Heukelom J, Thomsen TW, Mohr NM. Concurrent Proximal Fractures Are Rare in Distal Forearm Fractures: A National Cross-sectional Study. West J Emerg Med. 2019 Aug 26;20(5):747-759. doi: 10.5811/westjem.2019.5.42952. PubMed PMID: 31539332; PubMed Central PMCID: PMC6754191.

Oest SER, Swanson MB, Ahmed A, Mohr NM. Perceptions and Perceived Utility of Rural Emergency Department Telemedicine Services: A Needs Assessment. Telemed J E Health. 2019 Oct 3. doi: 10.1089/tmj.2019.0168. [Epub ahead of print] PubMed PMID: 31580783.

Swanson MB, Miller AC, Ward MM, Ullrich F, Merchant KA, Mohr NM. Emergency department telemedicine consults decrease time to interpret computed tomography of the head in a multi-network cohort. J Telemed Telecare. 2019 Nov 4:1357633X19877746. doi: 10.1177/1357633X19877746. [Epub ahead of print] PubMed PMID: 31684801.

Arulraja MD, Swanson MB, Mohr NM. Double inter-hospital transfer in Sepsis patients presenting to the ED does not worsen mortality compared to single inter-hospital transfer. J Crit Care. 2019 Nov 30;56:49-57. doi: 10.1016/j.jcrc.2019.11.018. [Epub ahead of print] PubMed PMID: 31837601.

Mohr NM, Campbell KD, Swanson MB, Ullrich F, Merchant KA, Ward MM. Provider-to-provider telemedicine improves adherence to sepsis bundle care in community emergency departments. J Telemed Telecare. 2020 Jan 5:1357633X19896667. doi: 10.1177/1357633X19896667. [Epub ahead of print] PubMed PMID: 31903840.

Miller AC, Ward MM, Ullrich F, Merchant KAS, Swanson MB, Mohr NM.  Emergency Department Telemedicine Consults are Associated with Faster Time-to-Electrocardiogram and Time-to-Fibrinolysis for Myocardial Infarction Patients. Telemed J E Health. 2020 Feb 28;. doi: 10.1089/tmj.2019.0273. [Epub ahead of print] PubMed PMID: 32109200.

Foley TM, Philpot BA, Davis AS, Swanson MB, Harland KK, Kuhn JD, Fuller BM, Mohr NM.  Implementation of an ED-based bundled mechanical ventilation protocol improves adherence to lung-protective ventilation. Am J Emerg Med. 2020 Feb 25;. doi: 10.1016/j.ajem.2020.02.053. [Epub ahead of print] PubMed PMID: 32139215.

Thinnes R, Swanson MB, Wetjen K, Harland KK, Mohr NM. Preferences for emergency medical service transport after childhood injury: An emergency department-based multi-methods study. Injury. 2020 May 13;. doi: 10.1016/j.injury.2020.04.036. [Epub ahead of print] PubMed PMID: 32507453.

Miller DG, Vakkalanka JP, Swanson MB, Nugent AS, Hagiwara Y. Is the Emergency Department an Inappropriate Venue for Code Status Discussions? Am J Hosp Palliat Care. 2020 Jul 2:1049909120938332. doi: 10.1177/1049909120938332. Epub ahead of print. PMID: 32613837.

Solie CJ, Swanson MB, Harland K, Blum C, Kin K, Mohr N. Two-Item Fall Screening Tool Identifies Older Adults at Increased Risk of Falling after Emergency Department Visit. West J Emerg Med. 2020 Aug 20;21(5):1275-1282. doi: 10.5811/westjem.2020.5.46991. PMID: 32970586.

Georgakakos PK, Swanson MB, Ahmed A, Mohr NM. Rural Stroke Patients Have Higher Mortality: An Improvement Opportunity for Rural Emergency Medical Services Systems. J Rural Health. 2020 Aug 5. doi: 10.1111/jrh.12502. Epub ahead of print. PMID: 32757239.

Weeks K, Swanson M, Hansen H, Merritt K, Nellis J, Charlton M, Reed A. An Unmet Need in Healthcare Leadership: A Survey of Practicing Physicians' Perspectives on Healthcare Delivery Science Education. J Healthc Leadersh. 2020 Oct 7;12:95-102. doi: 10.2147/JHL.S265377. PMID: 33117033; PMCID: PMC7548321.

Weeks K, Swanson M, Manorot A, Conley G, Nellis J, Charlton M, Reed A. Viewpoints on Healthcare Delivery Science Education Among Practicing Physicians in a Rural State. Adv Med Educ Pract. 2021 Jan 11;12:29-39. doi: 10.2147/AMEP.S285463. PMID: 33469404; PMCID: PMC7810585.

Mohr NM, Harland KK, Okoro UE, Fuller BM, Campbell K, Swanson MB, Simpson SQ, Parker EA, Mack LJ, Bell A, DeJong K, Faine B, Zepeski A, Mueller K, Chrischilles E, Carpenter CR, Jones MP, Ward MM. TELEmedicine as an intervention for sepsis in emergency departments: a multicenter, comparative effectiveness study (TELEvISED Study). J Comp Eff Res. 2021 Jan 20. doi: 10.2217/cer-2020-0141. Epub ahead of print. PMID: 33470848.

Teran, Frida

Cerpa VJ, Wu Y, Bravo E, Teran FA, Flynn RS, Richerson GB. Medullary 5-HT neurons: Switch from tonic respiratory drive to chemoreception during postnatal development. Neuroscience. 2017 Mar 6;344:1-14. doi: 10.1016/j.neuroscience.2016.09.002. Epub 2016 Sep 9. PubMed PMID: 27619736; PubMed Central PMCID: PMC5303637.

Teran FA, Massey CA, Richerson GB. Serotonin neurons and central respiratory chemoreception: where are we now?. Prog Brain Res. 2014;209:207-33. doi: 10.1016/B978-0-444-63274-6.00011-4. Review. PubMed PMID: 24746050; PubMed Central PMCID: PMC4486262.

Teran, FA, Massey, CA & Richerson, GB. Overview of Section on Current Research on Causes of SUDEP. In: Sudden unexpected death in epilepsy: a global conversation, eds. D. Chapman, B. Moss, R. Panelli, and R. Pollard, Epilepsy Australia Ltd, Camberwell, Victoria, 2018 edition.

Wu Y, Proch KL, Teran FA, Lechtenberg RJ, Kothari H, Richerson GB. Chemosensitivity of Phox2b-expressing retrotrapezoid neurons is mediated in part by input from 5-HT neurons. J Physiol. 2019 Mar 13;. Doi: 10.1113/JP277052. [Epub ahead of print] PubMed PMID: 30866045.

Teran FA, Kim Y, Crotts MS, Bravo E, Emaus KJ, Richerson GB. Time of Day and a Ketogenic Diet Influence Susceptibility to SUDEP in Scn1aR1407X/+ Mice. Front Neurol. 2019;10:278. doi: 10.3389/fneur.2019.00278. eCollection 2019. PubMed PMID: 30984098; PubMed Central PMCID: PMC6449461.

Wenker IC, Teran FA, Wengert ER, Wagley PK, Panchal PS, Blizzard EA, Saraf P, Wagnon JL, Goodkin HP, Meisler MH, Richerson GB, Patel MK. Postictal death is associated with tonic phase apnea in a mouse model of SUDEP. Ann Neurol. 2021 Feb 18. doi: 10.1002/ana.26053. Epub ahead of print. PMID: 33604927.

Todd, Brittany

Evans LP, Woll AW, Wu S, Todd BP, Hehr NN, Hedberg-Buenz A, Anderson MG, Newell EA, Ferguson PJ, Mahajan VB, Harper MM, Bassuk AG. Modulation of post-traumatic immune response using the IL-1 receptor antagonist anakinra for improved visual outcomes. J Neurotrauma. 2020 Feb 14. doi: 10.1089/neu.2019.6725. [Epub ahead of print] PubMed PMID: 32056479.

Todd, Dylan

Todd D, Bonthius DJ Jr, Sabalo LM, Roghair J, Karacay B, Bousquet SL, Bonthius DJ. Regional Patterns of Alcohol-Induced Neuronal Loss Depend on Genetics: Implications for Fetal Alcohol Spectrum Disorder. Alcohol Clin Exp Res. 2018 Sep;42(9):1627-1639. doi: 10.1111/acer.13824. Epub 2018 Jul 16. PubMed PMID: 29957842; PubMed Central PMCID: PMC6445660.

Plume JM, Todd D, Bonthius DJ. Viral Strain Determines Disease Symptoms, Pathology, and Immune Response in Neonatal Rats with Lymphocytic Choriomeningitis Virus Infection. Viruses. 2019 Jun 14;11(6). Doi: 10.3390/v11060552. PubMed PMID: 31207945.

Toral, Marcus

Schaefer KA, Toral MA, Velez G, Cox AJ, Baker SA, Borcherding NC, Colgan DF, Bondada V, Mashburn CB, Yu CG, Geddes JW, Tsang SH, Bassuk AG, Mahajan VB. Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses. Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2509-21. doi: 10.1167/iovs.15-18680. PubMed PMID: 27152965; PubMed Central PMCID: PMC4868102.

Banerjee S, Toral M, Siefert M, Conway D, Dorr M, Fernandes J. dHb9 expressing larval motor neurons persist through metamorphosis to innervate adult-specific muscle targets and function in Drosophila eclosion. Dev Neurobiol. 2016 Dec;76(12):1387-1416. doi: 10.1002/dneu.22400. Epub 2016 Jun 6. PubMed PMID: 27168166; PubMed Central PMCID: PMC5106342.

Toral MA, Velez G, Boudreault K, Schaefer KA, Xu Y, Saffra N, Bassuk AG, Tsang SH, Mahajan VB. Structural modeling of a novel SLC38A8 mutation that causes foveal hypoplasia. Mol Genet Genomic Med. 2017 May;5(3):202-209. doi: 10.1002/mgg3.266. eCollection 2017 May. PubMed PMID: 28546991; PubMed Central PMCID: PMC5441399.

Cabral T*, Toral MA*, Velez G, DiCarlo JE, Gore AM, Mahajan M, Tsang SH, Bassuk AG, Mahajan VB. Dissection of Human Retina and RPE-Choroid for Proteomic Analysis. J Vis Exp. 2017 Nov 12;(129). Doi: 10.3791/56203. PubMed PMID: 29155757; PubMed Central PMCID: PMC5755368. (*co-first authors)

Roybal CN, Velez G, Toral MA, Tsang SH, Bassuk AG, Mahajan VB. Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and mTOR as a Therapeutic Target. Am J Ophthalmol. 2018 Feb;186:152-163. doi: 10.1016/j.ajo.2017.11.025. Epub 2017 Dec 13. PubMed PMID: 29246578; PubMed Central PMCID: PMC5805631.

Li AS, Velez G, Darbro B, Toral MA, Yang J, Tsang SH, Ferguson PJ, Folk JC, Bassuk AG, Mahajan VB. Whole-Exome Sequencing of Patients with Posterior Segment Uveitis. Am J Ophthalmol. 2020 Jul 21:S0002-9394(20)30378-0. doi: 10.1016/j.ajo.2020.07.021. Epub ahead of print. PMID: 32707200.

van der Heide, Carly (Lewis)

Hedberg-Buenz A, Christopher MA, Lewis CJ, Fernandes KA, Dutca LM, Wang K, Scheetz TE, Abràmoff MD, Libby RT, Garvin MK, Anderson MG. Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification. Exp Eye Res. 2016 May;146:370-85. doi: 10.1016/j.exer.2015.09.011. Epub 2015 Oct 22. PubMed PMID: 26474494; PubMed Central PMCID: PMC4841761.

Hedberg-Buenz A, Christopher MA, Lewis CJ, Meyer KJ, Rudd DS, Dutca LM, Wang K, Garvin MK, Scheetz TE, Abràmoff MD, Harper MM, Anderson MG. RetFM-J, an ImageJ-based module for automated counting and quantifying features of nuclei in retinal whole-mounts. Exp Eye Res. 2016 May;146:386-92. doi: 10.1016/j.exer.2015.07.020. Epub 2015 Aug 14. PubMed PMID: 26283021; PubMed Central PMCID: PMC4753132.

Lewis CJ, Hedberg-Buenz A, DeLuca AP, Stone EM, Alward WLM, Fingert JH. Primary congenital and developmental glaucomas. Hum Mol Genet. 2017 Aug 1;26(R1):R28-R36. doi: 10.1093/hmg/ddx205. Review. PubMed PMID: 28549150; PubMed Central PMCID: PMC5886473.

Fingert JH, Miller K, Hedberg-Buenz A, Roos BR, Lewis CJ, Mullins RF, Anderson MG. Transgenic TBK1 mice have features of normal tension glaucoma. Hum Mol Genet. 2017 Jan 1;26(1):124-132. doi: 10.1093/hmg/ddw372. PubMed PMID: 28025332; PubMed Central PMCID: PMC6075615.

Chirco KR, Lewis CJ, Scheetz TE, Johnston RM, Tucker BA, Stone EM, Fingert JH, Mullins RF. Evaluation of sFLT1 protein levels in human eyes with the FLT1 rs9943922 polymorphism. Ophthalmic Genet. 2018 Jan-Feb;39(1):68-72. doi: 10.1080/13816810.2017.1369550. Epub 2017 Sep 26. PubMed PMID: 28949775; PubMed Central PMCID: PMC5751420.

van der Heide CJ, Alward WLM, Flamme-Wiese M, Riker M, Syed NA, Anderson MG, Carter K, Kuehn MH, Stone EM, Mullins RF, Fingert JH. Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye. Ophthalmol Glaucoma. 2018 Sep-Oct;1(2):132-138. doi: 10.1016/j.ogla.2018.08.004. Epub 2018 Aug 17. PubMed PMID: 30906929; PubMed Central PMCID: PMC6425711.

Alward WLM, van der Heide C, Khanna CL, Roos BR, Sivaprasad S, Kam J, Ritch R, Lotery A, Igo RP Jr, Cooke Bailey JN, Stone EM, Scheetz TE, Kwon YH, Pasquale LR, Wiggs JL, Fingert JH. Myocilin Mutations in Patients With Normal-Tension Glaucoma. JAMA Ophthalmol. 2019 Feb 28;. doi: 10.1001/jamaophthalmol.2019.0005. [Epub ahead of print] PubMed PMID: 30816940; PubMed Central PMCID: PMC6512256.

Hedberg-Buenz A, Dutca LM, Larson DR, Meyer KJ, Soukup DA, van der Heide CJ, Mercer HE, Wang K, Anderson MG. Mouse models and strain-dependency of Chédiak-Higashi syndrome-associated neurologic dysfunction. Sci Rep. 2019 May 1;9(1):6752. doi: 10.1038/s41598-019-42159-0. PubMed PMID: 31043676; PubMed Central PMCID: PMC6494809.

Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA, Allingham RR, Aung T, Van Der Heide CJ, Taylor KD, Rotter JI, Wang SJ, Bonnemaijer PWM, Williams SE, Abdullahi SM, Abu-Amero KK, Anderson MG, Akafo S, Alhassan MB, Asimadu I, Ayyagari R, Bakayoko S, Nyamsi PB, Bowden DW, Bromley WC, Budenz DL, Carmichael TR, Challa P, Chen YI, Chuka-Okosa CM, Cooke Bailey JN, Costa VP, Cruz DA, DuBiner H, Ervin JF, Feldman RM, Flamme-Wiese M, Gaasterland DE, Garnai SJ, Girkin CA, Guirou N, Guo X, Haines JL, Hammond CJ, Herndon L, Hoffmann TJ, Hulette CM, Hydara A, Igo RP Jr, Jorgenson E, Kabwe J, Kilangalanga NJ, Kizor-Akaraiwe N, Kuchtey RW, Lamari H, Li Z, Liebmann JM, Liu Y, Loos RJF, Melo MB, Moroi SE, Msosa JM, Mullins RF, Nadkarni G, Napo A, Ng MCY, Nunes HF, Obeng-Nyarkoh E, Okeke A, Okeke S, Olaniyi O, Olawoye O, Oliveira MB, Pasquale LR, Perez-Grossmann RA, Pericak-Vance MA, Qin X, Ramsay M, Resnikoff S, Richards JE, Schimiti RB, Sim KS, Sponsel WE, Svidnicki PV, Thiadens AAHJ, Uche NJ, van Duijn CM, de Vasconcellos JPC, Wiggs JL, Zangwill LM, Risch N, Milea D, Ashaye A, Klaver CCW, Weinreb RN, Ashley Koch AE, Fingert JH, Khor CC. Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. JAMA. 2019 Nov 5;322(17):1682-1691. doi: 10.1001/jama.2019.16161. PubMed PMID: 31688885.

Velez, Gabriel

Borcherding N, Kusner D, Kolb R, Xie Q, Li W, Yuan F, Velez G, Askeland R, Weigel RJ, Zhang W. Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells. Cancer Res. 2015 May 15;75(10):1972-82. doi: 10.1158/0008-5472.CAN-14-2761. Epub 2015 Mar 13. PubMed PMID: 25769722; PubMed Central PMCID: PMC4433621.

Velez G, Roybal CN, Colgan D, Tsang SH, Bassuk AG, Mahajan VB. Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease. JAMA Ophthalmol. 2016 Apr;134(4):444-8. doi: 10.1001/jamaophthalmol.2015.5934. PubMed PMID: 26848019; PubMed Central PMCID: PMC4833518.

Schaefer KA, Toral MA, Velez G, Cox AJ, Baker SA, Borcherding NC, Colgan DF, Bondada V, Mashburn CB, Yu CG, Geddes JW, Tsang SH, Bassuk AG, Mahajan VB. Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses. Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2509-21. doi: 10.1167/iovs.15-18680. PubMed PMID: 27152965; PubMed Central PMCID: PMC4868102.

Moshfegh Y, Velez G, Li Y, Bassuk AG, Mahajan VB, Tsang SH. BESTROPHIN1 mutations cause defective chloride conductance in patient stem cell-derived RPE. Hum Mol Genet. 2016 Jul 1;25(13):2672-2680. doi: 10.1093/hmg/ddw126. Epub 2016 May 18. PubMed PMID: 27193166; PubMed Central PMCID: PMC5181636.

Gakhar L, Bassuk AG, Velez G, Khan S, Yang J, Tsang SH, Mahajan VB. Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains. J Struct Biol. 2016 Dec;196(3):309-318. doi: 10.1016/j.jsb.2016.07.017. Epub 2016 Jul 27. PubMed PMID: 27474374; PubMed Central PMCID: PMC5118095.

Velez G, Roybal CN, Binkley E, Bassuk AG, Tsang SH, Mahajan VB. Proteomic Analysis of Elevated Intraocular Pressure with Retinal Detachment. Am J Ophthalmol Case Rep. 2017 Apr;5:107-110. doi: 10.1016/j.ajoc.2016.12.023. Epub 2017 Jan 3. PubMed PMID: 28825049; PubMed Central PMCID: PMC5560621.

Chin EK, Almeida DRP, Velez G, Xu K, Peraire M, Corbella M, Elshatory YM, Kwon YH, Gehrs KM, Boldt HC, Sohn EH, Russell SR, Folk JC, Mahajan VB. OCULAR HYPERTENSION AFTER INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT. Retina. 2017 Jul;37(7):1345-1351. doi: 10.1097/IAE.0000000000001364. PubMed PMID: 27806001; PubMed Central PMCID: PMC5411345.

Toral MA, Velez G, Boudreault K, Schaefer KA, Xu Y, Saffra N, Bassuk AG, Tsang SH, Mahajan VB. Structural modeling of a novel SLC38A8 mutation that causes foveal hypoplasia. Mol Genet Genomic Med. 2017 May;5(3):202-209. doi: 10.1002/mgg3.266. eCollection 2017 May. PubMed PMID: 28546991; PubMed Central PMCID: PMC5441399.

Cox AJ, Darbro BW, Laxer RM, Velez G, Bing X, Finer AL, Erives A, Mahajan VB, Bassuk AG, Ferguson PJ. Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO). PLoS One. 2017;12(3):e0169687. doi: 10.1371/journal.pone.0169687. eCollection 2017. PubMed PMID: 28301468; PubMed Central PMCID: PMC5354242.

Cox AJ, Darbro BW, Laxer RM, Velez G, Bing X, Finer AL, Erives A, Mahajan VB, Bassuk AG, Ferguson PJ. Correction: Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO). PLoS One. 2017;12(7):e0181222. doi: 10.1371/journal.pone.0181222. eCollection 2017. PubMed PMID: 28686717; PubMed Central PMCID: PMC5501673.

Velez G, Roybal CN, Binkley E, Bassuk AG, Tsang SH, Mahajan VB. Proteomic Analysis of Elevated Intraocular Pressure with Retinal Detachment. Am J Ophthalmol Case Rep. 2017 Apr;5:107-110. doi: 10.1016/j.ajoc.2016.12.023. Epub 2017 Jan 3. PubMed PMID: 28825049; PubMed Central PMCID: PMC5560621.

Cabral T, Toral MA, Velez G, DiCarlo JE, Gore AM, Mahajan M, Tsang SH, Bassuk AG, Mahajan VB. Dissection of Human Retina and RPE-Choroid for Proteomic Analysis. J Vis Exp. 2017 Nov 12;(129). Doi: 10.3791/56203. PubMed PMID: 29155757; PubMed Central PMCID: PMC5755368.

Velez G, Tsang SH, Tsai YT, Hsu CW, Gore A, Abdelhakim AH, Mahajan M, Silverman RH, Sparrow JR, Bassuk AG, Mahajan VB. Gene Therapy Restores Mfrp and Corrects Axial Eye Length. Sci Rep. 2017 Nov 23;7(1):16151. doi: 10.1038/s41598-017-16275-8. PubMed PMID: 29170418; PubMed Central PMCID: PMC5701072.

Roybal CN, Velez G, Toral MA, Tsang SH, Bassuk AG, Mahajan VB. Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and mTOR as a Therapeutic Target. Am J Ophthalmol. 2018 Feb;186:152-163. doi: 10.1016/j.ajo.2017.11.025. Epub 2017 Dec 13. PubMed PMID: 29246578; PubMed Central PMCID: PMC5805631.

Velez G, Bassuk AG, Colgan D, Tsang SH, Mahajan VB. Therapeutic drug repositioning using personalized proteomics of liquid biopsies. JCI Insight. 2017 Dec 21;2(24). doi: 10.1172/jci.insight.97818. PubMed PMID: 29263305; PubMed Central PMCID: PMC5752263.

Velez G, Machlab DA, Tang PH, Sun Y, Tsang SH, Bassuk AG, Mahajan VB. Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases. PLoS One. 2018 Feb 21;13(2):e0193250. doi: 10.1371/journal.pone.0193250. eCollection 2018. PMID: 29466423; PMCID: PMC5821407.

Velez G, Bassuk AG, Schaefer KA, Brooks B, Gakhar L, Mahajan M, Kahn P, Tsang SH, Ferguson PJ, Mahajan VB. A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay. Cold Spring Harb Mol Case Stud. 2018 Jun;4(3). doi: 10.1101/mcs.a002519. Print 2018 Jun. PubMed PMID: 29472286; PubMed Central PMCID: PMC5983175.

Wert KJ, Velez G, Cross MR, Wagner BA, Teoh-Fitzgerald ML, Buettner GR, McAnany JJ, Olivier A, Tsang SH, Harper MM, Domann FE, Bassuk AG, Mahajan VB. Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface. Free Radic Biol Med. 2018 Aug 20;124:408-419. doi: 10.1016/j.freeradbiomed.2018.06.024. Epub 2018 Jun 22. PubMed PMID: 29940351; PubMed Central PMCID: PMC6233711.

Liu KY, Sengillo JD, Velez G, Jauregui R, Sakai LY, Maumenee IH, Bassuk AG, Mahajan VB, Tsang SH. Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity. Orphanet J Rare Dis. 2018 Aug 15;13(1):138. doi: 10.1186/s13023-018-0885-4. PMID: 30111362; PMCID: PMC6094464.

Velez G, Tang PH, Cabral T, Cho GY, Machlab DA, Tsang SH, Bassuk AG, Mahajan VB. Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease. Transl Vis Sci Technol. 2018 Sep;7(5):12. doi: 10.1167/tvst.7.5.12. eCollection 2018 Sep. PubMed PMID: 30271679; PubMed Central PMCID: PMC6159735.

Machlab DA, Velez G, Bassuk AG, Mahajan VB. ProSave: an application for restoring quantitative data to manipulated subsets of protein lists. Source Code Biol Med. 2018;13:3. doi: 10.1186/s13029-018-0070-0. eCollection 2018. PubMed PMID: 30459825; PubMed Central PMCID: PMC6233572.

Tang PH, Velez G, Tsang SH, Bassuk AG, Mahajan VB. VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site. Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):282-293. doi: 10.1167/iovs.18-25624. PubMed PMID: 30657523; PubMed Central PMCID: PMC6735613.

Almeida DRP, Chin EK, Arjmand P, Velez G, Evans LP, Mahajan VB. Fibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy. Ophthalmic Surg Lasers Imaging Retina. 2018 Dec 1;49(12):e271-e277. doi: 10.3928/23258160-20181203-18. PubMed PMID: 30566713.

Jauregui R, Thomas AL, Liechty B, Velez G, Mahajan VB, Clark L, Tsang SH. SCAPER-associated nonsyndromic autosomal recessive retinitis pigmentosa. Am J Med Genet A. 2019 Feb;179(2):312-316. doi: 10.1002/ajmg.a.61001. Epub 2018 Dec 18. PubMed PMID: 30561111; PubMed Central PMCID: PMC6349500.

Sancho-Pelluz J, Cui X, Lee W, Tsai YT, Wu WH, Justus S, Washington I, Hsu CW, Park KS, Koch S, Velez G, Bassuk AG, Mahajan VB, Lin CS, Tsang SH. Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a RhoD190N mutation. Cell Mol Life Sci. 2019 Sep;76(18):3657-3665. doi: 10.1007/s00018-019-03090-9. Epub 2019 Apr 11. PubMed PMID: 30976840; PubMed Central PMCID: PMC7144803.

Velez G, Yang J, Li AS, Tsang SH, Bassuk AG, Mahajan VB. Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy. Sci Rep. 2019 May 20;9(1):7608. doi: 10.1038/s41598-019-44031-7. PubMed PMID: 31110225; PubMed Central PMCID: PMC6527583.

Cox AJ, Grady F, Velez G, Mahajan VB, Ferguson PJ, Kitchen A, Darbro BW, Bassuk AG. In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth. Genet Res (Camb). 2019 Jun 13;101:e8. doi: 10.1017/S0016672319000065. PubMed PMID: 31190668; PubMed Central PMCID: PMC7045018.

Abe K, Cox A, Takamatsu N, Velez G, Laxer RM, Tse SML, Mahajan VB, Bassuk AG, Fuchs H, Ferguson PJ, Hrabe de Angelis M. Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11872-11877. doi: 10.1073/pnas.1819825116. Epub 2019 May 28. PubMed PMID: 31138708; PubMed Central PMCID: PMC6575637.

Wert KJ, Koch SF, Velez G, Hsu CW, Mahajan M, Bassuk AG, Tsang SH, Mahajan VB. CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials. Hum Mutat. 2019 Dec;40(12):2377-2392. doi: 10.1002/humu.23894. Epub 2019 Aug 26. PubMed PMID: 31403230; PubMed Central PMCID: PMC7493429.

Lin Y, Xu CL, Velez G, Yang J, Tanaka AJ, Breazzano MP, Mahajan VB, Sparrow JR, Tsang SH. Novel REEP6 gene mutation associated with autosomal recessive retinitis pigmentosa. Doc Ophthalmol. 2020 Feb;140(1):67-75. doi: 10.1007/s10633-019-09719-1. Epub 2019 Sep 19. PubMed PMID: 31538292; PubMed Central PMCID: PMC731060

Velez G, Sun YJ, Khan S, Yang J, Herrmann J, Chemudupati T, MacLaren RE, Gakhar L, Wakatsuki S, Bassuk AG, Mahajan VB. Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants. Cell Rep. 2020 Jan 21;30(3):881-892.e5. doi: 10.1016/j.celrep.2019.12.077. PubMed PMID: 31968260; PubMed Central PMCID: PMC7001764.

Wert KJ, Velez G, Kanchustambham VL, Shankar V, Evans LP, Sengillo JD, Zare RN, Bassuk AG, Tsang SH, Mahajan VB. Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration. EBioMedicine. 2020 Feb;52:102636. doi: 10.1016/j.ebiom.2020.102636. Epub 2020 Feb 3. PubMed PMID: 32028070; PubMed Central PMCID: PMC7005447.

Sepah YJ*, Velez G*, Tang PH, Yang J, Chemudupati T, Li AS, Nguyen QD, Bassuk AG, Mahajan VB. Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target. Am J Ophthalmol Case Rep. 2020 Mar 6;18:100646. doi: 10.1016/j.ajoc.2020.100646. eCollection 2020 Jun. PubMed PMID: 32274442; PubMed Central PMCID: PMC7132169. (co-first authors).

Li AS, Velez G, Darbro B, Toral MA, Yang J, Tsang SH, Ferguson PJ, Folk JC, Bassuk AG, Mahajan VB. Whole-Exome Sequencing of Patients with Posterior Segment Uveitis. Am J Ophthalmol. 2020 Jul 21:S0002-9394(20)30378-0. doi: 10.1016/j.ajo.2020.07.021. Epub ahead of print. PMID: 32707200.

Velez G, Mahajan VB. Molecular Surgery: Proteomics of a Rare Genetic Disease Gives Insight into Common Causes of Blindness. iScience. 2020 Oct 13;23(11):101667. doi: 10.1016/j.isci.2020.101667. PMID: 33134897; PMCID: PMC7586135.

Voigt, Andrew

Voigt AP, Whitmore SS, Flamme-Wiese MJ, Riker MJ, Wiley LA, Tucker BA, Stone EM, Mullins RF, Scheetz TE. Molecular characterization of foveal versus peripheral human retina by single-cell RNA sequencing. Exp Eye Res. 2019 Jul;184:234-242. doi: 10.1016/j.exer.2019.05.001. Epub 2019 May 8. PubMed PMID: 31075224; PubMed Central PMCID: PMC6596422.

Borcherding N, Voigt AP, Liu V, Link BK, Zhang W, Jabbari A. Single-Cell Profiling of Cutaneous T-Cell Lymphoma Reveals Underlying Heterogeneity Associated with Disease Progression. Clin Cancer Res. 2019 May 15;25(10):2996-3005. doi: 10.1158/1078-0432.CCR-18-3309. Epub 2019 Feb 4. PMID: 30718356; PMCID: PMC6659117.

Borcherding N, Bormann NL, Voigt AP, Zhang W. TRGAted: A web tool for survival analysis using protein data in the Cancer Genome Atlas. Version 2. F1000Res. 2018 Aug 10 [revised 2018 Jan 1];7:1235. doi: 10.12688/f1000research.15789.2. eCollection 2018. PMCID: PMC6173115.

Feddersen CR, Wadsworth LS, Zhu EY, Vaughn HR, Voigt AP, Riordan JD, Dupuy AJ. A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. BMC Genomics. 2019 Jun 17;20(1):497. doi: 10.1186/s12864-019-5888-6. PubMed PMID: 31208320; PubMed Central PMCID: PMC6580595.

Feddersen CR, Schillo JL, Varzavand A, Vaughn HR, Wadsworth LS, Voigt AP, Zhu EY, Jennings BM, Mullen SA, Bobera J, Riordan JD, Stipp CS, Dupuy AJ. Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma. Cancer Res. 2019 Oct 1;79(19):5074-5087. doi: 10.1158/0008-5472.CAN-19-0244. Epub 2019 Aug 15. PMID: 31416844; PMCID: PMC6774858.

Voigt AP, Mulfaul K, Mullin NK, Flamme-Wiese MJ, Giacalone JC, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24100-24107. doi: 10.1073/pnas.1914143116. Epub 2019 Nov 11. PubMed PMID: 31712411; PubMed Central PMCID: PMC6883845.

Voigt AP, Binkley E, Flamme-Wiese MJ, Zeng S, DeLuca AP, Scheetz TE, Tucker BA, Mullins RF, Stone EM. Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations. Cells. 2020 Feb 13;9(2). pii: E438. doi: 10.3390/cells9020438. PubMed PMID: 32069977.

Stone NE, Voigt AP, Cooke JA, Giacalone JC, Hanasoge S, Mullins RF, Tucker BA, Sulchek T. Label-free microfluidic enrichment of photoreceptor cells. Exp Eye Res. 2020 Aug 6:108166. doi: 10.1016/j.exer.2020.108166. Epub ahead of print. PMID: 32771499

Mulfaul K, Giacalone JC, Voigt AP, Riker MJ, Ochoa D, Han IC, Stone EM, Mullins RF, Tucker BA. Stepwise differentiation and functional characterization of human induced pluripotent stem cell-derived choroidal endothelial cells. Stem Cell Res Ther. 2020 Sep 23;11(1):409. doi: 10.1186/s13287-020-01903-4. PMID: 32967716.

Voigt AP, Whitmore SS, Lessing ND, DeLuca AP, Tucker BA, Stone EM, Mullins RF, Scheetz TE. Spectacle: An interactive resource for ocular single-cell RNA sequencing data analysis. Exp Eye Res. 2020 Nov;200:108204. doi: 10.1016/j.exer.2020.108204. Epub 2020 Sep 7. PubMed PMID: 32910939; PubMed Central PMCID: PMC7655596.

Mullin NK, Voigt AP, Cooke JA, Bohrer LR, Burnight ER, Stone EM, Mullins RF, Tucker BA. Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease. Prog Retin Eye Res. 2020 Oct 29:100918. doi: 10.1016/j.preteyeres.2020.100918. Epub ahead of print. PMID: 33130253.

Voigt AP, Mullin NK, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell RNA sequencing in vision research: Insights into human retinal health and disease. Prog Retin Eye Res. 2020 Dec 28:100934. doi: 10.1016/j.preteyeres.2020.100934. Epub ahead of print. PMID: 33383180.

Walimbe, Ameya

Zhu Q, Venzke D, Walimbe AS, Anderson ME, Fu Q, Kinch LN, Wang W, Chen X, Grishin NV, Huang N, Yu L, Dixon JE, Campbell KP, Xiao J. Structure of protein O-mannose kinase reveals a unique active site architecture. Elife. 2016 Nov 23;5. doi: 10.7554/eLife.22238. PubMed PMID: 27879205; PubMed Central PMCID: PMC5142810.

Walimbe AS, Okuma H, Joseph S, Yang T, Yonekawa T, Hord JM, Venzke D, Anderson ME, Torelli S, Manzur A, Devereaux M, Cuellar M, Prouty S, Ocampo Landa S, Yu L, Xiao J, Dixon JE, Muntoni F, Campbell KP. POMK regulates dystroglycan function via LARGE-mediated elongation of matriglycan. Elife. 2020 Sep 25;9:e61388. doi: 10.7554/eLife.61388. Epub ahead of print. PMID: 32975514.

Weeks, Kristin

Weeks KS, Kahl AR, Lynch CF, Charlton ME. Racial/ethnic differences in thyroid cancer incidence in the United States, 2007-2014. Cancer. 2018 Apr 1;124(7):1483-1491. doi: 10.1002/cncr.31229. Epub 2018 Jan 16. PubMed PMID: 29338082; PubMed Central PMCID: PMC5867235.

Weeks KS, Lynch CF, West M, McDonald M, Carnahan R, Stewart SL, Charlton M. Impact of Rurality on Stage IV Ovarian Cancer at Diagnosis: A Midwest Cancer Registry Cohort Study. J Rural Health. 2020 Feb 20;. doi: 10.1111/jrh.12419. [Epub ahead of print] PubMed PMID: 32077162.

Weeks KS, Herbach E, McDonald M, Charlton M, Schweizer ML. Meta-Analysis of VTE Risk: Ovarian Cancer Patients by Stage, Histology, Cytoreduction, and Ascites at Diagnosis. Obstet Gynecol Int. 2020 Sep 3;2020:2374716. doi: 10.1155/2020/2374716. PMID: 32963543; PMCID: PMC7486642.

Weeks K, Swanson M, Hansen H, Merritt K, Nellis J, Charlton M, Reed A. An Unmet Need in Healthcare Leadership: A Survey of Practicing Physicians' Perspectives on Healthcare Delivery Science Education. J Healthc Leadersh. 2020 Oct 7;12:95-102. doi: 10.2147/JHL.S265377. PMID: 33117033; PMCID: PMC7548321.

Gao X, Weeks KS, Gribovskaja-Rupp I, Hassan I, Ward MM, Charlton ME. Provider Viewpoints in the Management and Referral of Rectal Cancer. J Surg Res. 2020 Oct 10:S0022-4804(20)30636-3. doi: 10.1016/j.jss.2020.08.073. Epub ahead of print. PMID: 33051062.

Weeks K, Lynch CF, West M, Carnahan R, O'Rorke M, Oleson J, McDonald M, Stewart SL; Ovarian Cancer Treatment Study, Charlton M. Rural disparities in surgical care from gynecologic oncologists among Midwestern ovarian cancer patients. Gynecol Oncol. 2020 Nov 17:S0090-8258(20)34114-7. doi: 10.1016/j.ygyno.2020.11.006. Epub ahead of print. PMID: 33218682.

Weeks K, Swanson M, Manorot A, Conley G, Nellis J, Charlton M, Reed A. Viewpoints on Healthcare Delivery Science Education Among Practicing Physicians in a Rural State. Adv Med Educ Pract. 2021 Jan 11;12:29-39. doi: 10.2147/AMEP.S285463. PMID: 33469404; PMCID: PMC7810585.

Whillock, Amy

Bangalore-Prakash P, Stunz LL, Mambetsariev N, Whillock AL, Hostager BS, Bishop GA. The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency. Blood Adv. 2017 Dec 26;1(27):2712-2723. doi: 10.1182/bloodadvances.2017009670. eCollection 2017 Dec 26. PubMed PMID: 29296923; PubMed Central PMCID: PMC5745131.

Whillock AL, Mambetsariev N, Lin WW, Stunz LL, Bishop GA. Author Correction: TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells. Sci Rep. 2019 Nov 20;9(1):17502. doi: 10.1038/s41598-019-53669-2. PubMed PMID: 31745166; PubMed Central PMCID: PMC6864106.

Zarei, Keyan

Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA. CF airway smooth muscle transcriptome reveals a role for PYK2. JCI Insight. 2017 Sep 7;2(17). doi: 10.1172/jci.insight.95332. eCollection 2017 Sep 7. PubMed PMID: 28878137; PubMed Central PMCID: PMC5621916.

Fischer AJ, Pino-Argumedo MI, Hilkin BM, Shanrock CR, Gansemer ND, Chaly AL, Zarei K, Allen PD, Ostedgaard LS, Hoffman EA, Stoltz DA, Welsh MJ, Alaiwa MHA. Mucus strands from submucosal glands initiate mucociliary transport of large particles. JCI Insight. 2019 Jan 10;4(1). Doi: 10.1172/jci.insight.124863. [Epub ahead of print] PubMed PMID: 30626743; PubMed Central PMCID: PMC6485365.

Ostedgaard LS, Price MP, Whitworth KM, Abou Alaiwa MH, Fischer AJ, Warrier A, Samuel M, Spate LD, Allen PD, Hilkin BM, Romano Ibarra GS, Ortiz Bezara ME, Goodell BJ, Mather SE, Powers LS, Stroik MR, Gansemer ND, Hippee CE, Zarei K, Goeken JA, Businga TR, Hoffman EA, Meyerholz DK, Prather RS, Stoltz DA, Welsh MJ. Lack of airway submucosal glands impairs respiratory host defenses. Elife. 2020 Oct 7;9:e59653. doi: 10.7554/eLife.59653. PMID: 33026343; PMCID: PMC7541087.

Zarei K, Stroik MR, Gansemer ND, Thurman AL, Ostedgaard LS, Ernst SE, Thornell IM, Powers LS, Pezzulo AA, Meyerholz DK, Stoltz DA. Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Lab Invest. 2020 Nov;100(11):1388-1399. doi: 10.1038/s41374-020-0474-8. Epub 2020 Jul 27. PubMed PMID: 32719544; PubMed Central PMCID: PMC7578062.

Zhu, Eliot

Feddersen CR, Wadsworth LS, Zhu EY, Vaughn HR, Voigt AP, Riordan JD, Dupuy AJ. A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. BMC Genomics. 2019 Jun 17;20(1):497. doi: 10.1186/s12864-019-5888-6. PubMed PMID: 31208320; PubMed Central PMCID: PMC6580595.

Feddersen CR, Schillo JL, Varzavand A, Vaughn HR, Wadsworth LS, Voigt AP, Zhu EY, Jennings BM, Mullen SA, Bobera J, Riordan JD, Stipp CS, Dupuy AJ. Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma. Cancer Res. 2019 Oct 1;79(19):5074-5087. doi: 10.1158/0008-5472.CAN-19-0244. Epub 2019 Aug 15. PMID: 31416844; PMCID: PMC6774858.

Feddersen CR, Wadsworth LS, Zhu EY, Vaughn HR, Voigt AP, Riordan JD, Dupuy AJ. A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. BMC Genomics. 2019 Jun 17;20(1):497. doi: 10.1186/s12864-019-5888-6. PubMed PMID: 31208320; PubMed Central PMCID: PMC6580595.

Vanneste M, Feddersen CR, Varzavand A, Zhu EY, Foley T, Zhao L, Holt KH, Milhem M, Piper R, Stipp CS, Dupuy AJ, Henry MD. Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis. Front Oncol. 2020 Apr 3;10:442. doi: 10.3389/fonc.2020.00442. eCollection 2020. PubMed PMID: 32346533; PubMed Central PMCID: PMC7169429.