This October, the distinguished Dr. Robert Lefkowitz from Duke University joined the long list of preeminent scientists chosen by Pharmacology graduate students to present the Michael J. Brody Lecture. Inaugurated by the Department of Pharmacology in 1993 and now part of the Distinguished Biomedical Scholar Lecture Series of the Carver College of Medicine, the annual lecture was established in honor of its namesake, Dr. Michael J. Brody, a long-time Professor of Pharmacology who was an esteemed cardiovascular researcher, an outstanding educator and mentor, and a leading voice in University governance. Dr. Lefkowitz, the James B. Duke Professor of Medicine and Professor of Biochemistry and Immunology at Duke University and an Investigator of the Howard Hughes Medical Institute, was a fitting choice for this honor. He is a researcher of unparalleled excellence, whose work towards the discovery and characterization of G protein-coupled receptors constituted revolutionary advancements in pharmacologic science. Among his many honors, Lefkowitz shared the 2012 Nobel Prize in Chemistry. His lecture, “Seven Transmembrane Receptors,” was extremely well received. All in Pharmacology thank Dr. Lefkowitz for helping us honor the legacy of Michael J. Brody.