Hiroyuki Oya, MD, PhD

Portrait
Associate Professor of Neurosurgery

Contact Information

Office
1624 JCP
200 Hawkins Dr
Iowa City, IA 52242
319-353-8452

Education

MD, Tottori University School of Medicine
Resident, Neurosurgery, Yokohama City University Hospital
Fellow, Neurosurgery, Yokohama City University Hospital
Postdoctoral Fellow, Neurology/Neurosurgery, University of Iowa Carver College of Medicine

Licensure and Certifications

Iowa Medical License - Iowa Board of Medicine
Board Certificate: Japan Neurosurgery Society - Japan Neurosurgical Society
Japan Medical License

Research Summary

Electrophysiology; Behavioral study of learning and memory; Plasticity of human brain functions

Publications

Kovach, C. K., Oya, H. & Kawasaki, H. (2018). The bispectrum and its relationship to phase-amplitude coupling. Neuroimage, 173, 518-39. PMID: 29481965.

Oya, H., Gander, P. E., Petkov, C. I., Adolphs, R., Nourski, K. V., Kawasaki, H., Howard, M. A. & Griffiths, T. D. (2018). Neural phase locking predicts BOLD response in human auditory cortex. Neuroimage, 169, 286-301. PMID: 29274745.

Kelley, R., Flouty, O., Emmons, E. B., Kim, Y., Kingyon, J., Wessel, J. R., Oya, H., Greenlee, J. D. & Narayanan, N. S. (2018). A human prefrontal-subthalamic circuit for cognitive control. Brain, 141(1), 205-16. PMID: 29190362.

Flouty, O., Reddy, C., Holland, M., Kovach, C., Kawasaki, H., Oya, H., Greenlee, J., Hitchon, P. & Howard, M. (2017). Precision surgery of rolandic glioma and insights from extended functional mapping. Clin Neurol Neurosurg, 163, 60-6. PMID: 29073500.

Baroni, F., van Kempen, J., Kawasaki, H., Kovach, C. K., Oya, H., Howard, M. A., Adp;[js, R. & Tsuchiya, N. (2017). Intracranial markers of conscious face perception in humans. Neuroimage, 162, 322-43. PMID: 28882629.

Dubois, J., Oya, H., Tyszka, J. M., Howard 3rd, M., Eberhardt, F. & Adolphs, R. (2017). Causal mapping of emotion networks in the human brain: Framework and initial findings. Neuropsychologia, pii: S0028-3932(17)30428-1 [Epub ahead of print]. PMID: 29146466.

Haun, A. M., Oizumi, M., Kovach, C. K., Kawasaki, H., Oya, H., Howard, M. A., Adolphs, R. & Tsuchiya, N. (2017). Conscious Perception as Integrated Information Patterns in Human Electrocorticography. eNeuro, pii: ENEURO.0085-17.2017. PMID: 29085895.

Nagahama, Y., Kovach, C. K., Ciliberto, M., Joshi, C., Rhone, A. E., Vesole, A., Gander, P. E., Nourski, K. V., Oya, H., `Howard 3rd, M. A., Kawasaki, H. & Dlouhy, B. J. (2017). Localization of musicogenic epilepsy to Heschl's gyrus and superior temporal plane: case report. J Neurosurg, [Epub ahead of print]. PMID: 28946181.

Katlowitz, K. A., Oya, H., Howard 3rd, M. A., Greenlee, J. D. & Long, M. A. (2017). Paradoxical vocal changes in a trained singer by focally cooling the right superior temporal gyrus. Cortex, 89, 111-9. PMID: 28282570.

Oya, H., Howard, M. A., Magnotta, V. A., Kruger, A., Griffiths, T. D., Lemieux, L., Carmichael, D. W., Petkov, C. i., Kawasaki, H., Kovach, C. K., Sutterer, M. J. & Aolphs, R. (2017). Mapping effective connectivity in the human brain with concurrent intracranial electrical stimulation and BOLD-fMRI. J Neurosci Methods, 277, 101-112. PMID: 28012852.

Kingyon, J., Behroozmand, R., Kelley, R., Oya, H., Kawasaki, H., Narayanan, N. S. & Greenlee, J. D. (2016). Corrigendum to "High-gamma band fronto-temporal coherence as a measure of functional connectivity in speech motor control" [Neuroscience 305 (2015) 15-25]. pp. pii: S0306-4522(16)30324-4. Neuroscience. PMID: 27448528.

Abel, T. J., Rhone, A. E., Nourski, K. V., Ando, T. K., Oya, H., Kovach, C. K., Kawasaki, H., Howard 3rd, M. A. & Tranel, D. (2016). Beta modulation reflects name retrieval in the human anterior temporal lobe: an intracranial recording study. J Neurophysiol, 115(6), 3052-61. PMID: 27075536.

Long, M. A., Katlowitz, K. A., Svirsky, M. A., Clary, R. C., Byun, T. M., Majaj, N., Oya, H., Howard 3rd, M. A. & Greenlee, J. D. (2016). Functional Segregation of Cortical Regions Underlying Speech Timing and Articulation. Neuron, 89(6), 1187-93. PMID: 26924439.

Sedley, W., Gander, P. E., Kumar, S., Kovach, C. K., Oya, H., Kawasaki, H., Howard, M. A. & Griffiths, T. D. (2016). Neural Signatures of Perceptual Inference. Elife, pii: e11476. PMID: 26949254.

Behroozmand, R., Oya, H., Nourski, K. V., Kawasaki, H., Larson, C. R., Brugge, J. F., Howard 3rd, M. A. & Greenlee, J. D. (2016). Neural Correlates of Vocal Production and Motor Control in Human Heschl's Gyrus. J Neurosci, 36(7), 2302-15. PMID: 26888939.

Rhone, A. E., Nourski, K. V., Oya, H., Kawasaki, H., Howard 3rd, M. A. & McMurray, B. (2016). Can you hear me yet? An intracranial investigation of speech and non-speech audiovisual interactions in human cortex. Lang Cogn Neurosci, 31(2), 284-302. PMID: 27182530.

Kingyon, J., Behroozmand, R., Kelley, R., Oya, H., Kawasaki, H., Narayanan, N. S. & Greenlee, J. D. (2015). High-gamma band fronto-temporal coherence as a measure of functional connectivity in speech motor control. Neuroscience, 305, 15-25. PMID: 26232713.

Jenison, R. L., Reale, R. A., Armstrong, A. L., Oya, H., Kawasaki, H. & Howard 3rd, M. A. (2015). Sparse Spectro-Temporal Receptive Fields Based on Multi-Unit and High-Gamma Responses in Human Auditory Cortex. (Vols. 10). (9), pp. e0137915. PLoS One. PMID: 26367010.

Nourski, K. V., Steinschneider, M., Rhone, A. E., Oya, H., Kawasaki, H., Howard 3rd, M. A. & McMurray, B. (2015). Sound identification in human auditory cortex: Differential contribution of local field potentials and high gamma power as revealed by direct intracranial recordings. Brain Lang, 148, 37-50. PMID: 25819402.

Dlouhy, D. J., Gehlbach, B. K., Kreple, C. J., Kawasaki, H., Oya, H., Buzza, C., Granner, M. A., Welsh, M. J., Howard, M. A., Wemmie, J. A. & Richerson, G. B. (2015). Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation. J Neurosci, 35(28), 10281-9. PMID: 26180203.

Sedly, W., Gander, P. E., Kumar, S., Oya, H., Kovach, C. K., Nourski, K. V., Kawasaki, H., Howard 3rd, M. A. & Griffiths, T. D. (2015). Intracranial Mapping of a Cortical Tinnitus System using Residual Inhibition. Curr Biol, 25(9), 1208-14. PMID: 25913402.

Behroozmand, R., Shebek, R., Hansen, D. R., Oya, H., Robin, D. A., Howard 3rd, M. A. & Greenlee, J. D. (2015). Sensory-motor networks involved in speech production and motor control: an fMRI study. Neuroimage, 109, 418-28. PMID: 25623499.

Nourski, K. V., Steinschneider, M., Oya, H., Kawasaki, H. & Howard 3rd, M. A. (2015). Modulation of response patterns in human auditory cortex during a target detection task: An intracranial electrophysiology study. Int J Psychophysiol, 95(2), 191-201. PMID: 24681353.

Abel, T. J., Rhone, A. E., Nourski, K. V., Kawasaki, H., Oya, H., Griffiths, T. D., Howard 3rd, M. A. & Tranel, D. (2015). Direct physiologic evidence of a heteromodal convergence region for proper naming in human left anterior temporal lobe. J Neurosci, 35(4), 1513-20. PMID: 25632128.

Nourski, K. V., Steinschneider, M., McMurray, B., Kovach, C. K., Oya, H., Kawasaki, H. & Howard 3rd, M. A. (2014). Functional organization of human auditory cortex: investigation of response latencies through direct recordings. Neuroimage, 101, 598-609. PMID: 25019680.

Grosland, N. M., Gillies, G. T., Shurig, R., Stoner, K., Viljoen, S., Dalm, B. D., Oya, H., Fredericks, D. C., Gibson-Corley, K., Reddy, C., Wilson, S. & Howard III, M. A. (2014). Finite-Element Study of the Performance Characteristics of an Intradural Spinal Cord Stimulator. J Med Devices, 8(4), 041012. DOI: 10.1115/1.4028421.

Nourski, K. V., Steinschneider, M., Oya, H., Kawasaki, H., Jones, R. D. & Howard, M. A. (2014). Spectral organization of the human lateral superior temporal gyrus revealed by intracranial recordings. Cereb Cortex, 24(2), 340-52. PMID: 23048019.

Huang, Q., Oya, H., Flouty, O. E., Reddy, C. G., Howard 3rd, M. A., Gillies, G. T. & Utz, M. (2014). Comparison of spinal cord stimulation profiles from intra- and extradural electrode arrangements by finite element modelling. Med Biol Eng Comput, 52(6), 531-8. PMID: 24771203.

Steinschneider, M., Nourski, K. V., Rhone, A. E., Kawasaki, H., Oya, H. & Howard 3rd, M. A. (2014). Differential activation of human core, non-core and auditory-related cortex during speech categorization tasks as revealed by intracranial recordings. Front Neurosci, 11(8), 240. PMID: 25157216.

Abel, T. J., Rhone, A. E., Nourski, K. V., Granner, M. A., Oya, H., Griffiths, T. D., Tranel, D. T., Kawasaki, H. & Howard, M. A. (2014). Mapping the temporal pole with a specialized electrode array: technique and preliminary results. Physiol Meas, 35(3), 323-37. PMID: 24480831.

Gibson-Corley, K. N., Flouty, O., Oya, H., Gillies, G. T. & Howard, M. A. (2014). Postsurgical pathologies associated with intradural electrical stimulation in the central nervous system: design implications for a new clinical device. Biomed Res Int, 989175. PMID: 24800260.

Dalm, B., Viljoen, S., Dahdaleh, N. S., Reddy, C. G., Brennan, T. J., Oya, H., Wilson, S., Safayi, S., Jeffery, N. D., Gillies, G. T. & Howard, M. A. (2014). Revisiting intradural spinal cord stimulation: an introduction to a novel intradural spinal cord stimulation device. Innovative Neurosurgery, 21(1-4), 13-20. DOI: 10.1515/ins-2014-0005.

Greenlee, J. D., Behroozmand, R., Nourski, K. V., Oya, H., Kawasaki, H. & Howard, M. A. (2014). Using speech and electrocorticography to map human auditory cortex. Conf Proc IEEE Eng Med Biol Soc, 2014, 6798-801. PMID: 25571557.

Viljoen, S., Oya, H., Reddy, C. G., Dalm, B., Shurig, R., Gillies, G. T. & Howard, M. A. (2013). Apparatus for simulating dynamic interactions between the spinal cord and soft-coupled intradural implants. Rev Sci Instrum, 84(11), 114303. PMID: 24289414.

Oya, H., Nourski, K. V., Rhone, E. A., Kawasaki, H. & Howard, M. A. (2013). Non-linear dependency between spiking response and gamma-band power of local field potentials in the human auditory cortex. BMC Neurosci, 14(Suppl 1), P175.

Nourski, K. V., Etler, C. P., Brugge, J. F., Oya, H., Kawasaki, H., Reale, R. A., Abbas, P. J., Brown, C. J. & Howard, M. A. (2013). Direct recordings from the auditory cortex in a cochlear implant user. J Assoc Res Otolaryngol, 14(3), 435-50. PMID: 23519390.

Ai, L., Oya, H., Howard, M. A. & Xiong, J. (2013). Functional MRI detectional of hemodynamic response of repeated median nerve stimulation. Magn Reson Imaging, 21(4), 550-4. PMID: 23228312.

Greenlee, J. D., Behroozmand, R., Larson, C. R., Jackson, A. W., Chen, F., Hansen, D. R., Oya, H., Kawasaki, H. & Howard, M. A. (2013). Sensory-motor interactions for vocal pitch monitoring in non-primary human auditory cortex. PLoS One, 8(4), e60783. PMID: 23577157.

Nourski, K. V., Brugge, J. F., Reale, R. A., Kovach, C. K., Oya, H., Kawasaki, H., Jenison, R. L. & Howard, M. A. (2013). Coding of repetitive transients by auditory cortex on posterolateral superior temporal gyrus: an intracranial electrophysiological study. J Neurophysiol, 109(5), 1283-95. PMID: 23236002.

Flouty, O., Oya, H., Kawasaki, H., Reddy, C. G., Fredericks, D. C., Gibson-Corley, K. N., Jeffrey, N. D., Gillies, G. & Howard, M. A. (2013). Intracranial somatosensory responses with direct spinal cord stimulation in anesthetized sheep. PLoS One, 8(2), e56266. PMID: 23457542.

Abel, T. J., Flouty, O., Kawasaki, H., Oya, H. & Howard, M. A. (2013). Category- and entity-specific activation of neuronal populations in the temporal pole in response to naming proper nouns. (Vols. 119). (2), pp. A545-6. J Neurosurg.

Abel, T. J., Flouty, O., Oya, H., Kawasaki, H., Reddy, C. & Howard, M. A. (2013). Cortical responses to intra- and extra-dural electrical stimulation of mammalian spinal cord. (Vols. 119). (2), pp. A558. J Neurosurg.

Garrell, P. C., Bakken, H., Greenlee, J. D., Volkov, I., Reale, R. A., Oya, H., Kawasaki, H., Howard, M. A. & Brugge, J. F. (2013). Functional Connection Between Posterior Superior Temporal Gyrus and Ventrolateral Prefrontal Cortex in Human. Cereb Cortex, 23(10), 2309-2321. PMID: 22879355.

Greenlee, J. D., Behroozmand, R., Larson, C. R., Jackson, A. W., Chen, F., Hansen, D. R., Oya, H., Kawasaki, H. & Howard, M. A. (2013). Sensory-motor interactions for vocal pitch monitoring in non-primary human auditory cortex. PLoS One, 8(4), e60783. PMID: 23577157.

Oya, H., Safayi, S., Jeffery, N. D., Viljoen, S., Reddy, C. G., Dalm, B. D., Kanwal, J. K., Gillies, G. T. & Howard, M. A. (2013). Soft-coupling suspension system for an intradural spinal cord stimulator: Biophysical performance characteristics. J Appl Phys, 114(16), 164701-7. DOI: 10.1063/1.4827195.

Flouty, O. E., Oya, H., Kawasaki, H., Wilson, S., Reddy, C. G., Jeffrey, N. D., Brennan, T. J., Gibson-Corley, K. N., Utz, M., Gillies, G. T. & Howard, M. A. (2012). A new device concept for directly modulating spinal cord pathways: initial in vivo experimental results. Physiol Meas, 33(12), 2003-15. PMID: 23151433.

Gibson-Coley, K. N., Oya, H., Flouty, O. E., Fredericks, D. C., Jeffrey, N. D., Gillies, G. T. & Howard, M. A. (2012). Ovine tests of novel spinal cord neuromodulator and dentate ligament fixation method. J Invest Surg, 25(6), 366-74. PMID: 23215793.

Oya, H., Howard, M. A., Shurig, R. & Gillies, G. T. (2012). Spinal canal surrogate for testing intradural implants. J Med Eng Technol, 36(8), 407-10. PMID: 22953718.

Nourski, K. V., Steinschneider, M., Oya, H., Kawasaki, H., Jones, R. D. & Howard, M. A. (2012). Spectral organization of the human lateral superior temporal gyrus revealed by intracranial recordings. Cereb Cortex. PMID: 23048019.

Kawasaki, H., Tsuchiya, N., Kovach, C. K., Nourski, K. V., Oya, H., Howard, M. A. & Adolphs, R. (2012). Processing of facial emotion in the human fusiform gyrus. J Cogn Neurosci, 24(6), 1358-70. PMID: 22185494.

Oya, H., Reddy, C. G., Dahdaleh, N. S., Wilson, S., Howard, M. A., Jeffery, N. D., Utz, M. & Gillies, G. T. (2012). Applier tool for intradural spinal cord implants. J Med Eng Technol, 36(3), 169-73. PMID: 22339111.

Steinschneider, M., Nourski, K. V., Kawasaki, H., Oya, H., Brugge, J. F. & Howard, M. A. (2011). Intracranial study of speech-elicited activity on the human posterolateral temporal gyrus. Cereb Cortex, 21(10), 2332-47. PMID: 21368087.

Kumar, S., Sedley, W., Nourski, K. V., Kawasaki, H., Oya, H., Patterson, R. D., Howard, M. A., Friston, K. J. & Griffith, T. D. (2011). Predictive Coding and Pitch Processing in the Auditory Cortex. J Cogn Neurosci, 23(10), 3084-94. PMID: 21452943.

Greenlee, J. D., Jackson, A. W., Chen, F. X., Larson, C. R., Oya, H., Kawasaki, H., Chen, H. M. & Howard, M. A. (2011). Human Auditory Cortical Activation during Self-Vocalization. PLoS One, 6(3), e14744. PMID: 21390228.

Kovach, C. K., Tsuchiya, N., Kawasaki, H., Oya, H., Howard, M. A. & Adolphs, R. (2011). Manifestation of ocular-muscle EMG contamination in human intracranial recordings. Neuroimage, 54(1), 213-33. PMID: 20696256.

Jenison, R. L., Rangel, A., Oya, H., Kawasaki, H. & Howard, M. A. (2011). Value encoding in single neurons in the human amygdala during decision making. J Neurosci, 31(1), 331-8. PMID: 21209219.

Kitagawa, H., Fujiki, R., Yoshimura, K., Oya, H. & Kato, S. (2011). Williams syndrome is an epigenome-regulator disease. Endocr J, 58(2), 77-85. PMID: 21242649.

Reddy, C. G., Dahdaleh, N. S., Albert, G., Chen, F., Hansen, D. R., Nourski, K. V., Kawasaki, H., Oya, H. & Howard, M. A. (2010). A method for placing Heschl gyrus depth electrodes. J Neurosurgery, 112(6), 1301-7. PMID: 19663547.

Griffith, T. D., Kumar, S., Sedley, W., Nourski, K. V., Kawasaki, H., Oya, H., Patterson, R. D., Brugge, J. F. & Howard, M. A. (2010). Direct recordings of pitch responses from human auditory cortex. Curr Biol, 20(12), 1128-32. PMID: 20605456.

Dahdaleh, N. S., Lindley, T. E., Kirby, P. A., Oya, H. & Howard, M. A. (2009). A "neurosurgical crisis" of sickle cell disease. J Neurosurgery Pediatr, 4(6), 532-5. PMID: 19951039.

Nourski, K. V., Reale, R. A., Oya, H., Kawasaki, H., Kovach, C. K., Chen, H., Howard, M. A. & Brugge, J. F. (2009). Temporal envelope of time-compressed speech represented in the human auditory cortex. J Neurosci, 29(49), 15564-75. PMID: 20007480.

Brugge, J. F., Nourski, K. V., Oya, H., Reale, R. A., Kawasaki, H., Steinschneider, M. & Howard, M. A. (2009). Coding of repetitive transients by auditory cortex on Heschl's gyrus. J Neurophysiology, 102(4), 2358-74. PMID: 19675285.

Reddy, C. G., Reddy, G. G., Kawasaki, H., Oya, H., Miller, L. E. & Howard, M. A. (2009). Decoding movement-related cortical potentials from electrocorticography. Neurosurg Focus, 27(1), E11. PMID: 19569886.

Oya, H., Kawasaki, H., Dahdaleh, N. S., Wemmie, J. A. & Howard, M. A. (2009). Stereotactic atlas-based depth electrode localization in the human amygdala. Stereotact Funct Neurosurg, 87(4), 219-28. PMID: 19556831.

Tuschiya, N., Kawasaki, H., Oya, H., Howard, M. A. & Adolphs, R. (2008). Decoding face information in time, frequency and space from direct intracranial recordings of the human brain. PLoS One, 3(12), e3892. PMID: 19065268.

Brugge, J. F., Volkov, I. O., Oya, H., Kawasaki, H., Reale, R. A., Fenoy, A., Steinschneider, M. & Howard, M. A. (2008). Functional localization of auditory cortical fields of human: click-train simulation. Hear Res, 238(1-2), 12-24. PMID: 18207680.

Greenlee, J. D., Oya, H., Kawasaki, H., Volkov, I. O., Severson, M. A., Howard, M. A. & Brugge, J. F. (2007). Functional connections within the human inferior frontal gyrus. J Comp Neurol, 503(4), 550-9. PMID: 17534935.

Oya, H., Poon, P. W., Brugge, J. F., Reale, R. A., Kawasaki, H., Volkov, I. O. & Howard, M. A. (2007). Functional connections between auditory cortical fields in humans by Granger causality analysis of intra-cranial evoked potentials to sounds: comparison of two methods. Biosystems, 89(1-3), 198-207. PMID: 17184906.

Reale, R. A., Galvert, G. A., Thesen, T., Jenison, R. L., Kawasaki, H., Oya, H., Howard, M. A. & Brugge, J. F. (2007). Auditory-visual processing represented in the human superior temporal gyrus. Neuroscience, 145(1), 162-84. PMID: 17241747.

Kawasaki, H., Adolphs, R., Oya, H., Kovach, C. K., Damasio, H., Kaufman, O. & Howard, M. A. (2005). Analysis of single-unit responses to emotional scenes in human ventromedial prefrontal cortex. J Cogn Neurosci, 17(10), 1509-18. PMID: 16269093.

Oya, H., Adolphs, R., Kawasaki, H., Bechara, A., Damasio, A. & Howard, M. A. (2005). Electrophysiological correlates of reward prediction error recorded in the human prefrontal cortex. Proc Natl Acad Sci U S A, 102(23), 8351-6. PMID: 15928095.

Steinschneider, M., Volko, I. O., Fishman, Y. I., Oya, H., Arezzo, J. C. & Howard, M. A. (2005). Intracortical responses in human and monkey primary auditory cortex support a temporal processing mechanism for encoding of the voice onset time phonetic parameter. Cereb Cortex, 15(2), 170-86. PMID: 15238437.

Greenlee, J. D., Oya, H., Kawasaki, H., Volkov, I. O., Kaufman, O. P., Covach, C. K., Howard, M. A. & Brugge, J. F. (2004). A functional connection between inferior frontal gyrus and orofacial motor cortex in human. J Neurophysiol, 92(2), 1153-64. PMID: 15056683.

Bakken, H. E., Kawasaki, H., Oya, H., Greenlee, J. D. & Howard, M. A. (2003). A device for cooling localized regions of human cerebral cortex. Technical note. J Neurosurg, 99(3), 604-8. PMID: 12959453.

Oya, H., Kawasaki, H., Howard, M. A. & Adolphs, R. (2002). Electrophysiological responses in the human amygdala discriminate emotion categories of complex visual stimuli. J Neurosci, 22(21), 9502-12. PMID: 12417674.