Publications

Liping Yu, Ravi P. Yadav, and Nikolai O. Artemyev. (2017) NMR resonance assignments of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) in complex with a farnesyl ligand.  Biomol. NMR Assign., 11, 111-115.  DOI: 10.1007/s12104-017-9730-2.
 

Liam Hovey, C. Andrew Fowler, Ryan Mahling, Zesen Lin, Mark Stephen Miller, Dagan C. Marx, Jesse B. Yoder, Elaine H. Kim, Kristin M. Tefft, Brett C. Waite, Michael D. Feldkamp, Liping Yu, Madeline A. Shea. (2017) Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2.  Biophys. Chem., 224, 1-19. DOI:10.1016/j.bpc.2017.02.006.
 

Xu Liu, David C. Speckhard, Tyson R. Shepherd, Young Joo Sun, Sarah R. Hengel, Liping Yu, C. Andrew Fowler, Lokesh Gakhar, & Ernesto J. Fuentes. (2016) Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2053-2066. DOI: 10.1016/j.str.2016.08.019
 

Brian D. Fink, Fan Bai, Liping Yu, & William I. Sivitz. (2016) Impaired utilization of membrane potential by complex II-energized mitochondria of obese, diabetic mice assessed using ADP recycling methodology.  Am. J. Physiol. Regul. Integr. Comp. Physiol., 311, R756-R763. DOI: 10.1152/ajpregu.00232.2016.  
 

Adina M. Kilpatrick, Jerry E. Honts, Heidi M. Sleister, & C. Andrew Fowler. (2016) Solution NMR structures of the C-domain of Tetrahymena cytoskeletal protein Tcb2 reveal distinct calcium-induced structural rearrangements. Proteins, 84, 1748-1756. DOI: 10.1002/prot.25111
 

David C. Briggs, Takako Yoshida-Moriguchi, Tianqing Zheng, David Venzke, Mary Anderson, Andrea Strazzulli, Marco Moracci, Liping Yu, Erhard Hohenester, & Kevin P. Campbell. (2016) Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat. Chem. Biol., 12(10), 810-814. DOI:10.1038/nchembio.2146.
 

Adina M. Kilpatrick, Theodore E. Gurrola, Robert C. Sterner, Heidi M. Sleister, Jerry E. Honts, & C. Andrew Fowler. (2016) Backbone and side-chain chemical shift assignments for the C-terminal domain of Tcb2, a cytoskeletal calcium-binding protein from Tetrahymena thermophila. Biomol NMR Assign., 10, 281-5. DOI: 10.1007/s12104-016-9684-9

Sarah R. Hengel, Eva Malacaria, Laura Folly da Silva Constantino, Fletcher E. Bain, Andrea Diaz, Brandon G. Koch, Liping Yu, Meng Wu, Pietro Pichierri, M. Ashley Spies, & Maria Spies (2016) Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells. eLife, 5, e14740. DOI:10.7554/eLife.14740.
 

Samuel A. J. Trammell, Liping Yu, Philip Redpath, Marie E. Migaud, & Charles Brenner. (2016) Nicotinamide riboside is a major NAD+ precursor vitamin in bovine milk. Journal of Nutrition,146(5), 957-963. DOI: 10.3945/jn.116.230078.   
 

Fan Bai, Brian D. Fink, Liping Yu, & William I. Sivitz. (2016) Voltage-dependent regulation of complex II energized mitochondrial oxygen flux. PLoS One, 11(5):e0154982. DOI:10.1371/journal.pone.0154982. 
 

Tatiana V. Mishanina, Liping Yu, Kalani Karunaratne, Dibyendu Mondal, John M. Corcoran, Michael A. Choi, & Amnon Kohen. (2016) An unprecedented mechanism of nucleotide methylation in organisms containing thyX. Science, 351 (6272), 507-510.
 

Tyler P. Rasmussen, Yuejin Wu, Mei-ling A. Joiner, Olha M. Koval, Nicholas R. Wilson, Elizabeth D. Luczak, Qinchuan Wang, Biyi Chen, Zhan Gao, Zhiyong Zhu, Brett A. Wagner, Jamie Soto, Michael L. McCormick, William Kutschke, Robert M. Weiss, Liping Yu, Ryan L. Boudreau, E. Dale Abel, Fenghuang Zhan, Douglas R. Spitz, Garry R. Buettner, Long-Sheng Song, Leonid V. Zingman, & Mark E. Anderson. (2015) Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart. Proc. Natl. Acad. Sci. USA, 112(29), 9129-9134.
 

George Dialynas, Om K. Shrestha, Jessica M. Ponce, Monika Zwerger, Dylan A. Thiemann, Grant H. Young, Steven Moore, Liping Yu, Jan Lammerding, & Lori L. Wallrath. (2015) Myopathic lamin mutations cause reductive stress and activate the Nrf2/Keap-1 pathway. PLoS Genet. 11(5): e1005231. DOI:10.1371/journal.pgen.1005231.
 

Liping Yu , Brian D. Fink , & William I. Sivitz. (2015) Simultaneous quantification of mitochondrial ATP and ROS production. Methods Mol. Biol., 1264:149-59. DOI:10.1007/978-1-4939-2257-4_14.
 

Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns, & William I. Sivitz. (2014) A mitochondrial-targeted coenzyme Q analog prevents weight gain and ameliorates hepatic dysfunction in high fat-fed mice. J. Pharmacol. Exp. Ther., 351, 699-708. DOI:10.1124/jpet.114.219329
 

Tobias Willer, Kei-ichiro Inamori, David Venzke, Corinne Harvey, Greg Morgensen, Yuji Hara, Daniel Beltran Valero de Bernabe, Liping Yu, Kevin M. Wright, & Kevin P. Campbell. (2014) The glucuronyltransferase B4GAT1 is required for initiation of LARGE mediated α-dystroglycan functional glycosylation. eLife, 3, e03941. DOI: 10.7554/eLife.03941.
 

Theresa L. Gioannini, Athmane Teghanemt, DeSheng Zhang, Gregory Esparza, Liping Yu, & Jerrold Weiss. (2014) Purified monomeric ligand.MD-2 complexes reveal molecular and structural requirements for activation and antagonism of TLR4 by Gram-negative bacterial endotoxins. Immunol. Res., 59, 3-11. DOI:10.1007/s12026-014-8543-y.
 

Liping Yu, Brian D. Fink, Judith A. Herlein, Christine L. Oltman, Kathryn G. Lamping, & William I. Sivitz. (2014) Dietary fat, fatty acid saturation and mitochondrial bioenergetics. J. Bioenerg. Biomembr., 46, 33-44.
 

Tabitha A. Peterson, Liping Yu, & Robert C. Piper. (2013) Backbone and side-chain NMR assignments for the C-terminal domain of mammalian Vps28. Biomol. NMR Assign., DOI: 10.1007/s12104-013-9537-8.
 

Aaron M. Ver Heul, C. Andrew Fowler, S. Ramaswamy, & Robert C. Piper. (2013) Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2. J Biol Chem., 288, 6890-902. DOI: 10.1074/jbc.M112.413781
 

Takako Yoshida-Moriguchi, Tobias Willer, Mary E. Anderson, David Venzke, Tamieka Whyte, Francesco Muntoni, Hane Lee, Stanley F. Nelson, Liping Yu, & Kevin P. Campbell. (2013) SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Science, 341, 896-899.
 

Xu Liu, Tyson R. Shepherd, Ann M. Murray, Zhen Xu, & Ernesto J. Fuentes. (2013) The Structure of the Tiam1 PDZ Domain/ Phospho-Syndecan1 Complex Reveals a Ligand Conformation that Modulates Protein Dynamics. Structure, 21, 342-354. DOI: 10.1016/j.str.2013.01.004
 

Natasha Pashkova, Lokesh Gakhar, Stanley C. Winistorfer, Anna B. Sunshine, Matthew Rich, Maitreya J. Dunham, Liping Yu, & Robert C. Piper. (2013) The yeast Alix homolog Bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.  Developmental Cell, 25, 520-533.
 

Kyle B. Williams, Atsushi Yahashiri, S. J. Ryan Arends, David L. Popham, C. Andrew Fowler, & David S. Weiss. (2013) Nuclear magnetic resonance solution structure of the peptidoglycan-binding SPOR domain from Escherichia coli DamX: insights into septal localization. Biochemistry, 52, 627-39. DOI: 10.1021/bi301609e

Liping Yu, Brian D. Fink, Judith A. Herlein, & William I. Sivitz. (2013) Mitochondrial function in diabetes: Novel methodology and new insight.  Diabetes, 62, 1833-1842.

Liping Yu, Rachel L. Phillips, DeSheng Zhang, Athmane Teghanemt, Jerrold P. Weiss, & Theresa L. Gioannini. (2012) NMR studies of hexaacylated endotoxin bound to wild-type and F126A mutant MD-2 and MD-2/TLR4 ectodomain complexes.  J. Biol. Chem., 287, 16346-16355.

Post, D. M. B.*, Yu, L.*, Krasity, B. C.* (*these authors contributed equally), Choudhury, B., Mandel, M. J., Brennan, C. A., Ruby, E. G., McFall-Ngai, M. J., Gibson, B. W., & Apicella, M. A. (2012) O-antigen and core carbohydrate of Vibrio fischeri lipopolysaccharide: composition and analysis of their role in Euprymna scolopes light organ colonization. J. Biol. Chem., 287, 8515-8530.
 

Kei-ichiro, I, Yoshida-Moriguchi, T., Hara Y., Anderson, M. E., Yu, L., & Campbell K. P. (2012) Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE. Science, 335, 93-96.
 

Qiu, Jiang; Yu, Liping; & Kirsch, Lee E. (2011) Estimated pKa values for specific amino acid residues in daptomycin.  J. Pharm. Sci., 100, 4225-4233.
 

Feldkamp, Michael D.; Yu, Liping; & Shea, Madeline A. (2011) Structural and energetic determinants of apo calmodulin binding to the IQ-motif of the NaV1.2 voltage-dependent sodium channel. Structure, 19, 733-747.
 

Tyson R. Shepherd & Ernesto J. Fuentes. (2011) Structural and Thermodynamic Analysis of PDZ–Ligand Interactions. Methods Enzymol., 488, 81-100. DOI: 10.1016/B978-0-12-381268-1.00004-5
 

O'Donnell, S. E., Yu, L., Fowler, C. A., & Shea, M. A. (2011) Recognition of beta-calcineurin by the domains of calmodulin: thermodynamic and structural evidence for distinct roles. Proteins, 79, 765-786.
 

Pashkova, N., Gakhar, L., Winistorfer, S. C., Yu, L., Ramaswamy, S., & Piper, R. C. (2010) WD40 repeat propellers define a ubiquitin binding domain that regulates turnover of F-box proteins. Mol. Cell, 40, 433-443.
 

Shepherd, T. R., Klaus, S. M., Liu, X., Ramaswamy, S., DeMali, K. A. & Fuentes, E. J. (2010) The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell–Matrix Adhesion. J. Mol. Biol., 398, 730-746. DOI: 10.1016/j.jmb.2010.03.047
 

Apicella, M. A., Post, D. M., Fowler, A. C., Jones, B. D., Rasmussen, J. A., Hunt, J. R., Imagawa, S., Choudhury, B., Inzana, T. J., Maier, T. M., Frank, D. W., Zahrt, T. C., Chaloner, K., Jennings, M. P., McLendon, M. K., & Gibson, B. W. (2010) Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis. PLoS One, 5, e11060. DOI: 10.1371/journal.pone.0011060.
 

Feldkamp, M. D., O’Donnell, S. E., Yu, L., & Shea, M. A. (2010) Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin. Proteins, 78, 2265-2282.
 

Yoshida-Moriguchi, T., Yu, L., Stalnaker, S. H., Davis, S., Kunz, S., Madson, M., Oldstone, M. B. A., Schachter, H., Wells, L., & Campbell, K. P. (2010) O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding. Science, 327, 88-92.
 

Piazza, M., Yu, L., Teghanemt, A., Gioannini, T., Weiss, J., & Peri, F. (2009) Evidence of a specific interaction between new synthetic antisepsis agents and CD14. Biochemistry, 48, 12337-12344.