Grant Awardees March-April 2015
Date: Thursday, May 7, 2015
Thursday, May 07, 2015
Congratulations to Carver College of Medicine Grant Awardees from March-April 2015!
| Name | Department | Sponsor | Proposal Title |
| Abel, E. Dale | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Insulin Inhibition of betaAR signaling in the myocardium |
| Ahrens, Richard | Pediatrics | N30 Pharmaceuticals, Inc. | A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Study of N91115 to Evaluate Safety and Pharmacokinetics in Patients with Cystic Fibrosis Homozygous for the F508del-CFTR Mutation |
| Ahrens, Richard | Pediatrics | Seattle Children's Research Institute | Early Intervention in Cystic Fibrosis Exacerbation (eICE) |
| Anderson, Michael | Molecular Physiology & Biophysics | US Department of Veterans Affairs | Therapy of Nocturnal Intraocular Pressure Elevation Causing Glaucoma Progression |
| Bender, David | Obstetrics & Gynecology | Society of Gynecologic Oncology | SGO Cervical Outcomes Registry |
| Berg, Daniel | Internal Medicine | Millennium Pharmaceuticals, Inc. | A Phase 2 Trial of MLN0264 in Previously Treated Patients With Advanced or Metastatic Pancreatic Adenocarcinoma Expressing Guanylyl Cyclase C (GCC) |
| Boyden, Alexander | Pathology | National Multiple Sclerosis Society | The role of CD8+ regulatory T cells in modulating B cell function during EAE |
| Brennan, Timothy | Anesthesia | Concentric Analgesics, Inc. | Effect of CA-008 infiltration on Acute Pain from Incision |
| Brophy, Patrick | Pediatrics | Amgen, Inc. | Amgen Study 20130356 |
| Brophy, Patrick | Pediatrics | Seattle Children's Research Institute | Recombinant Erythropoientin Protects Against Chronic Kidney Disease |
| Comellas, Alejandro | Internal Medicine | AstraZeneca Pharmaceuticals LP | A 12-week Phase IIa, Double-blind, Placebo-controlled, Randomized Study |
| Cullen, Joseph | Surgery | US Department of Health & Human Services, National Institutes of Health | Pharmacological Ascorbate as a Radiosensitizer in Pancreatic Cancer |
| Ellermeier, Craig | Microbiology | Entera Health, Inc. | Entera Health |
| Engelhardt, John | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Center for Gene Therapy of Cystic Fibrosis |
| Ford, Bradley | Pathology | Accelerate Diagnostics, Inc. | Accelerate Clinical Trial Clinical Lab Model |
| Ford, Bradley | Pathology | Cepheid | Cepheid Clinical Study |
| Giudici, Michael | Internal Medicine | Cardionomic, Inc. | Cardiac Autonomic Nerve Activation to Increase Contractility |
| Giudici, Michael | Internal Medicine | Medtronic, Inc. | VICTORY AF trial |
| Grobe, Justin | Pharmacology | American Diabetes Association | Required Interaction of Leptin with Angiotensin in Metabolic Control |
| Hansen, Marlan | Otolaryngology - Head & Neck Surgery | Auris Medical | Efficacy and Safety of AM-101 in the Treatment of Acute Peripheral Tinnitus 2 (TACTT2) |
| Hodgson-Zingman, Denice | Internal Medicine | St. Jude Medical, Inc. | EP Fellowship Grant 2015-16 academic year |
| Hoffman, Eric | Radiology | US Department of Health & Human Services, National Institutes of Health | Defining the role of early pulmonary vascular disease in COPD |
| Hoffman, Eric | Radiology | US Department of Health & Human Services, National Institutes of Health | SPIROMICS-Radiology Center |
| Horwitz, Phillip | Internal Medicine | Edwards Lifesciences LLC | PARTNER 2 Sapien 3i Continued Access Protocol (CAP) |
| Horwitz, Phillip | Internal Medicine | St. Jude Medical, Inc. | Interventional Cardiology Fellowship Grant 2015-16 academic year |
| Ince, Dilek | Internal Medicine | Chimerix, Inc. | A Phase 3, Open-label, Multicenter Study of the Safety/Tolerability and Efficacy of Brincidofovir (CMX001) for the Prevention of Adenovirus (AdV) Disease in Subjects with Asymptomatic AdV Infection at Risk of Progression and for the Treatment of Subjects |
| Joshi, Charuta | Pediatrics | GW Pharmaceuticals | JOSHI- GW Pharmaceuticals - GWEP1423 |
| Joshi, Charuta | Pediatrics | GW Pharmaceuticals | JOSHI - GW Pharmaceuticals - An open label extension study to investigate the safety of cannabidiol (GWP42003-P; CBD) in children and adults with inadequately controlled Dravet or Lennox-Gastaut Syndromes |
| Kline, Joel | Internal Medicine | Amgen, Inc. | A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and |
| Light-McGroary, KellyAnn | Internal Medicine | RiboCor, Inc. | A Randomized, Double-Blind, Placebo-controlled Study To Evaluate D-Ribose For The Treatment Of Congestive Heart Failure |
| Lim, Tiffany Yue-Fai | Microbiology | US Department of Health & Human Services, National Institutes of Health | The Role of Inflammasomes in Bacterial Co-Infection during Cutaneous Leishmaniasis |
| Lindgren, Scott | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Comparing Behavioral Asssessments Using Telehealth for Children with Autism |
| Link, Brian | Internal Medicine | Kite Pharma, Inc. | Outcomes in Relapsed and Refractory Diffuse Large B-Cell Lymphoma: Analysis of the University of Iowa/Mayo Clinic Molecular Epidemiology Resource |
| Mahajan, Vinit | Ophthalmology & Visual Sciences | US Department of Health & Human Services, National Institutes of Health | Mechanism-based Therapies for Photoreceptor Degeneration |
| Mahajan, Vinit | Ophthalmology & Visual Sciences | US Department of Health & Human Services, National Institutes of Health | Evaluating GWAS AMD Candidate Loci by Gene Editing in Human iPS Cells |
| Mangalam, Ashutosh | Pathology | National Multiple Sclerosis Society | Therapeutic potential of combination therapy using Human Gut-derived commensal bacteria and conventional MS drugs |
| Mathews, Katherine | Pediatrics | Sarepta Therapeutics | Sarepta 203 |
| Mathews, Katherine | Pediatrics | Sarepta Therapeutics | Sarepta 204 |
| Mathews, Katherine | Pediatrics | Pfizer, Inc. | Pfizer 210966/B5161002 Study |
| Milhem, Mohammed | Internal Medicine | Mayo Clinic | A Randomized Phase II Study of Sequential Biotherapy with Aflibercept and High Dose IL-2 versus High Dose IL-2 alone in Patients with Inoperable Stage III or Stage IV Melanoma: Efficacy and Biomarker Study. |
| Milhem, Mohammed | Internal Medicine | NewLink Genetics Corporation | A Phase IIB Study of Ipilimumab with or without HyperAcute-Melanoma Immunotherapy for Stage IV Melanoma Patients |
| Milhem, Mohammed | Internal Medicine | Janssen Research & Development, Inc. | A randomized controlled study of YONDELIS (Trabectedin) or Dacarbazine for the treatment of advanced liposarcoma or Leiomyosarcoma previously treated with Anthracycline and Ifosfamide |
| Milhem, Mohammed | Internal Medicine | Northwestern University | NU 13S02 Multicenter, Open-Label Phase II Study of Daily Oral Regorafenib for |
| Miller, Delwyn | Psychiatry | Otsuka Pharmaceutical Company, Ltd. | PRELAPSE - A Cluster Randomized, Multi-center, Parallel-group, Rater-blind Study Comparing Treatment with Aripiprazole Once Monthly and Treatment as Usual on Effectiveness in First Episode and Early Phase Illness in Schizophrenia |
| Nugent, Andrew | Program in Emergency Medicine | EPIC Research and Diagnostics, Inc. | EPIC Traumatic Brain Injury Feasibility Study |
| Paulsen, Jane | Psychiatry | University of California, Irvine | CSF-Enhanced-Aggregation Biomarker to Monitor Huntington's Disease Progression |
| Paulsen, Jane | Psychiatry | University of Michigan | Validation of the HD-HRQoL (Huntington Disease Quality of Life Measure) |
| Paulsen, Jane | Psychiatry | Auspex Pharmaceuticals, Inc. | An Open-Label, Long Term Safety Study of SD-809 ER in Patients with Chorea Associated with Huntington Disease (ARC-HD) |
| Philibert, Robert | Psychiatry | University of Georgia | Vulnerability to Drug Use and HIV: Advancing Prevention for Rural African Americans |
| Pieper, Andrew | Psychiatry | Calico | Calico / Pieper Laboratory |
| Polyak, Steven | Internal Medicine | AbbVie Inc. | A Long-Term Non-Interventional Registry to Assess Safety and Effectiveness of HUMIRA (Adalimumab) in Patients with Moderately to Severely Active Ulcerative Colitis |
| Polyak, Steven | Internal Medicine | University of Michigan | A Randomized Controlled Trial of High Dose Vitamin D Therapy in Crohn's Disease |
| Price, Nathan | Pediatrics | Duke University | A Phase 1, Open-label, Multi-center Study to Determine the Pharmacokinetics and Safety of Solithromycin as Add-on Therapy in Adolescents and Children with Suspected or Confirmed Bacterial Infection |
| Randak, Christoph | Pediatrics | Cystic Fibrosis Foundation | Potentiating F508 CRTR Channel Function with an Adenylate Kinase Inhhibitor |
| Rosenthal, Gary | Internal Medicine | University of Kansas Medical Center Research Institute, Inc. | Greater Plains Collaborative Clinical Data Research Network |
| Roy, Rupali | Internal Medicine | Pharmacyclics, Inc. | A Multicenter Open-Label Phase 2a Study of Ibrutinib With or |
| Sabharwal, Rasnapreet | Internal Medicine | Tarix Pharmaceuticals Limited | Neurohumoral Actions of Angiotensin-(1-7) Analogs in Limb Girdle MD and ALS |
| Samuel, Isaac | Surgery | Foundation for Surgical Fellowships | Fellowship in Bariatric Surgery |
| Schartz, Kevin | Radiology | US Department of Health & Human Services, National Institutes of Health | Modern ROC Software for Multi- and Single-Reader Diagnostic Imaging Studies |
| Schartz, Kevin | Radiology | University of California, Santa Barbara | Utility-Based Assessment of Diagnostic Imaging Performance |
| Schultz, Michael | Radiology | University of Texas Health Science Center at Houston | Development of Hybrid Somatostatin Analogs for Surgical Guidance |
| Schultz, Susan | Psychiatry | University of California, San Diego | Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease - Tau (A4-Tau) Addendum |
| Segar, Jeffrey | Pediatrics | InfaCare Pharmaceutical Corporation | A 48-52 Month Blinded-Outcomes Follow Up Study of Patients Having Received Stannsoporfin or Placebo in Clinical Trial 64,185-205 |
| Serrano Russi, Alvaro | Pediatrics | Arkansas Children's Hospital Research Institute | IBEM-IS Data Entry Project |
| Sigmund, Curt | Pharmacology | American Heart Association | University of Iowa Strategically Focused Hypertension Research Center |
| Stapleton, Jack | Internal Medicine | Bavarian Nordic | BN-POX-MVA-037 |
| Stapleton, Jack | Internal Medicine | US Department of Veterans Affairs | The effects of Hepatitis C Virus (HCV) E2 protein on host immunomodulation |
| Stevens, Hanna | Psychiatry | Robert Leet & Clara Guthrie Patterson Trust | Developmental Psychopathology and Prenatal Stress Mechanisms and Prevention of Risk |
| Stevens, Hanna | Psychiatry | Yale University | Behavioral Epidemiology of Intensive In-Home Child and Adolescent Psychiatric Services |
| Stone, Edwin | Ophthalmology & Visual Sciences | Foundation Fighting Blindness | FFB-MAK-Associated RP Research Fund |
| Taylor, Eric | Biochemistry | US Department of Health & Human Services, National Institutes of Health | Regulation of Hepatic Gluconeogenesis by the Mitochondrial Pyruvate Carrier |
| Tricot, Guido | Internal Medicine | Novartis Pharmaceuticals Corporation | Exploit whether LBH589 can deplete the myeloma drug-resistant fraction |
| Turvey, Carolyn | Psychiatry | Baylor College of Medicine | One-Day Intervention for Depression and Impairment in Migraine Patients |
| Vaena, Daniel | Internal Medicine | Bristol-Myers Squibb Company | A Phase II Single Arm Clinical Trial of Nivolumab (BMS-936558) in Subjects with Metastatic or Unresectable Urothelial Cancer who have Progressed or Recurred Following Treatment with a Platinum Agent |
| Vaena, Daniel | Internal Medicine | TRACON Pharmaceuticals, Inc. | A Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone (Including a Lead-In Phase 1B Dose-Escalation Portion) in Patients with Advanced or Metastatic Renal Cell Carcinoma |
| Vaena, Daniel | Internal Medicine | AstraZeneca Pharmaceuticals LP | A Phase II Trial to Evaluate the Efficacy of AZD6094 (HMPL-504) in Patients with Papillary Renal Cell Carcinoma (PRCC) |
| Weigel, Ronald | Surgery | US Department of Health & Human Services, National Institutes of Health | RET as a Novel Therapeutic Target for Breast Cancer |
| Weiner, George | Cancer Center | US Department of Health & Human Services, National Institutes of Health | Cancer Center Support Grant - (CCSG) |
| Weiss, David | Microbiology | US National Science Foundation | REU Site: Microbiology at The University of Iowa |
| Wibbenmeyer, Lucy | Surgery | Queen's University, Kingston General Hospital, Ontario, Canada | A Randomized Trials of the Enteral Glutamine to Minimize Thermal Injury |
| Xue, Hai-Hui | Microbiology | US Department of Health & Human Services, National Institutes of Health | Tcf/Lef-b-catenin in T cell identity and cancer |
| Zavazava, Nicholas | Internal Medicine | ReproCELL Inc. | 3D Differentiation of human-induced pluripotent stem cells into insuling-producing cells using a bioactive ECM scaffold |