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Anna E. Merrill, PhD, DABCC

Portrait
Associate Director of Clinical Chemistry
Clinical Assistant Professor of Pathology

Contact Information

Primary Office
6234 Carver Pavilion (RCP)
200 Hawkins Drive
Iowa City, IA 52242
319-678-8400

Education

BA, Chemistry and Spanish, St. Olaf College
PhD, Chemistry, University of Wisconsin
Postdoctoral Research Fellow, Quantitative omics for studying the oral microbiome in dental and systemic disease, University of Wisconsin, Marshfield Clinic Research Foundation
Postdoctoral Fellow, Clinical Chemistry, University of Washington

Licensure and Certifications

Diplomate - American Board of Clinical Chemistry

Publications

Sharma, A., Greene, D. N., Chambliss, A. B., Farnsworth, C. W., French, D., Herman, D. S., Kavsak, P. A., Merrill, A. E., Lo Margaret, S. Y., Lyon, M. E., Winston-McPherson, G., Pearson, L. N., SoRelle, J. A., Waring, A. C. & Schmidt, R. L. (2021). The Effect of the Covid-19 Shutdown on Glycemic Testing and Control. Clinica chimica acta; international journal of clinical chemistry. PMID: 33932408.

Vickers, M. A., Sariol, A., Leon, J., Ehlers, A., Locher, A. V., Dubay, K. A., Collins, L., Voss, D., Odle, A. E., Holida, M., Merrill, A. E., Perlman, S. & Knudson, C. M. (2021). Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID-19 convalescent plasma donors. Transfusion. PMID: 33829513.

Humble, R. M., Merrill, A. E., Ford, B. A., Diekema, D. J. & Krasowski, M. D. (2021). Practical Considerations for Implementation of SARS-CoV-2 Serological Testing in the Clinical Laboratory: Experience at an Academic Medical Center. Acad Pathol, 8, 23742895211002802. PMID: 33889715.

Steffen, H. A., Swartz, S. R., Jackson, J. B., Kenne, K. A., Ten Eyck, P. P., Merryman, A. S., Castaneda, C. N., Marsden, K., Maxwell, T., Merrill, A. E., Krasowski, M. D. & Rysavy, M. B. (2021). SARS-CoV-2 Infection during Pregnancy in a Rural Midwest All-delivery Cohort and Associated Maternal and Neonatal Outcomes. American journal of perinatology. PMID: 33611783.

Parsons, M. G., Halvorson, T. S., Isaacson, A. L., Blau, J. L. & Merrill, A. E. (2020). No Longer Benign: Altered Mental Status and Apparent Coagulopathy in a Woman with Monoclonal Gammopathy of Undetermined Significance. Journal of Applied Laboratory Medicine. DOI: 10.1093/jalm/jfaa167.

Merrill, A. E., Malvik, N. M., Ford, D. C. & Krasowski, M. D. (2020). Continuation of Over-the-Counter Biotin Supplements in the Inpatient Setting: An Unexpected Source of Laboratory Error. Journal of Applied Laboratory Medicine. DOI: 10.1093/jalm/jfaa167.

Jacob, D., Merrill, A. E., Voss, D. R., Bebber, T., Davis, S. R., Kulhavy, J. & Krasowski, M. D. (2020). Data on length of parathyroidectomy surgery and intraoperative parathyroid hormone (PTH) assay turnaround times following a switch in the location for intraoperative PTH testing from near point-of-care to central laboratory. Data in brief, 32, 106252. PMID: 32953954.

Jacob, D., Lal, G., Voss, D. R., Bebber, T., Davis, S. R., Kulhavy, J., Sugg, S. L., Merrill, A. E. & Krasowski, M. D. (2020). Evaluation of switch from satellite laboratory to central laboratory for testing of intraoperative parathyroid hormone. Practical laboratory medicine, 22, e00176. PMID: 32923573.

Merrill, A. E., Jackson, J. B., Ehlers, A., Voss, D. & Krasowski, M. D. (2020). Head-to-Head Comparison of Two SARS-CoV-2 Serology Assays. Journal of Applied Laboratory Medicine. PMID: 32717056.

Merrill, J. E., Chambliss, A. B. (2020). Water and Electrolyte Balance. In W. Clark , M. A. Marzinke (Eds.) Contemporary Practice in Clinical Chemistry. (4th Edition), pp. 651-663. Elsevier. DOI: 10.1016/B978-0-12-815499-1.00037-5.

Eigsti, R. L., Krasowski, M. D., Vidholia, A. & Merrill, A. E. (2020). Data on interference indices in body fluid specimens submitted for clinical laboratory analysis. Data in brief, 30, 105408. PMID: 32258276.

Eigsti, R. L., Krasowski, M. D., Vidholia, A. & Merrill, A. E. (2020). Review of interference indices in body fluid specimens submitted for clinical chemistry analyses. Practical laboratory medicine, 19, e00155. PMID: 32099890.

Simonson, P. D., Kim, K. H., Winston-McPherson, G., Parakh, R. S., Yamaguchi, D., Merrill, A. E., Dickerson, J. A. & Greene, D. N. (2019). Characterization of bilirubin interference in three commonly used digoxin assays. Clinical Biochemistry, 63, 102-105. DOI: 10.1016/j.clinbiochem.2018.10.006.

Mays, J. A., Greene, D. N., Merrill, A. E. & Mathias, P. C. (2018). Evidence-based validation of hemolysis index thresholds by use of retrospective clinical data. Journal of Applied Laboratory Medicine, 109-114.

Winston-McPherson, G., Merrill, A. E., Lo, S. Y., Hoofnagle, A. N. & Greene, D. N. (2017). Interassay Comparison of the Tumor Markers CA125, CA15.3, and CA27.29. Journal of Applied Laboratory Medicine, 17-24.

Mays, J. A., Greene, D. N., Poon, A. & Merrill, A. E. (2017). Pseudohypophosphatemia associated with high-dose liposomal amphotericin B therapy
. Clinical Biochemistry, 967-971.

Merrill, A. E., Khan, J., Dickerson, J. A., Holmes, D. T., Harris, N. S. & Greene, D. N. (2016). Method-to-method variability in urine albumin measurements. Clinica chimica acta; international journal of clinical chemistry, 460, 114-9. PMID: 27315746.

Baughman, J. M., Rose, C. M., Kolumam, G., Webster, J. D., Wilkerson, E. M., Merrill, A. E., Rhoads, T. W., Noubade, R., Katavolos, P., Lesch, J., Stapleton, D. S., Rabaglia, M. E., Schueler, K. L., Asuncion, R., Domeyer, M., Zavala-Solorio, J., Reich, M., DeVoss, J., Keller, M. P., Attie, A. D., Hebert, A. S., Westphall, M. S., Coon, J. J., Kirkpatrick, D. S. & Dey, A. (2016). NeuCode Proteomics Reveals Bap1 Regulation of Metabolism. Cell reports, 16(2), 583-595. PMID: 27373151.

Merrill, A. E. (2016). Vitamin D testing. (Vols. 35). The ABCs of pediatric laboratory medicine.

Merrill, A. E., Holmes, D. T., Severin, N. & Greene, D. N. (2016). Persistently elevated human chorionic gonadotropin in a menopausal woman. Journal of Applied Laboratory Medicine, 315-318. DOI: 10.1373/jalm.2016.021428.

Rose, C. M., Rush, M. J., Riley, N. M., Merrill, A. E., Kwiecien, N. W., Holden, D. D., Mullen, C., Westphall, M. S. & Coon, J. J. (2015). A calibration routine for efficient ETD in large-scale proteomics. Journal of the American Society for Mass Spectrometry, 26(11), 1848-57. PMID: 26111518.

Rhoads, T. W., Prasad, A., Kwiecien, N. W., Merrill, A. E., Zawack, K., Westphall, M. S., Schroeder, F. C., Kimble, J. & Coon, J. J. (2015). NeuCode Labeling in Nematodes: Proteomic and Phosphoproteomic Impact of Ascaroside Treatment in Caenorhabditis elegans. Molecular & cellular proteomics : MCP, 14(11), 2922-35. PMID: 26392051.

Richards, A. L., Merrill, A. E. & Coon, J. J. (2015). Proteome sequencing goes deep. Current opinion in chemical biology, 24, 11-7. PMID: 25461719.

Chasman, D., Ho, Y. H., Berry, D. B., Nemec, C. M., MacGilvray, M. E., Hose, J., Merrill, A. E., Lee, M. V., Will, J. L., Coon, J. J., Ansari, A. Z., Craven, M. & Gasch, A. P. (2014). Pathway connectivity and signaling coordination in the yeast stress-activated signaling network. Molecular systems biology, 10, 759. PMID: 25411400.

Merrill, A. E., Hebert, A. S., MacGilvray, M. E., Rose, C. M., Bailey, D. J., Bradley, J. C., Wood, W. W., El Masri, M., Westphall, M. S., Gasch, A. P. & Coon, J. J. (2014). NeuCode labels for relative protein quantification. Molecular & cellular proteomics : MCP, 13(9), 2503-12. PMID: 24938287.

Rhoads, T. W., Rose, C. M., Bailey, D. J., Riley, N. M., Molden, R. C., Nestler, A. J., Merrill, A. E., Smith, L. M., Hebert, A. S., Westphall, M. S., Pagliarini, D. J., Garcia, B. A. & Coon, J. J. (2014). Neutron-encoded mass signatures for quantitative top-down proteomics. Analytical chemistry, 86(5), 2314-9. PMID: 24475910.

Ulbrich, A., Merrill, A. E., Hebert, A. S., Westphall, M. S., Keller, M. P., Attie, A. D. & Coon, J. J. (2014). Neutron-encoded protein quantification by peptide carbamylation. Journal of the American Society for Mass Spectrometry, 25(1), 6-9. PMID: 24178922.

Hebert, A. S., Merrill, A. E., Stefely, J. A., Bailey, D. J., Wenger, C. D., Westphall, M. S., Pagliarini, D. J. & Coon, J. J. (2013). Amine-reactive neutron-encoded labels for highly plexed proteomic quantitation. Molecular & cellular proteomics : MCP, 12(11), 3360-9. PMID: 23882030.

Merrill, A. E., Coon, J. J. (2013). Quantifying proteomes and their post-translational modifications by stable isotope label-based mass spectrometry. Current opinion in chemical biology, 17(5), 779-86. PMID: 23835517.

Rose, C. M., Merrill, A. E., Bailey, D. J., Hebert, A. S., Westphall, M. S. & Coon, J. J. (2013). Neutron encoded labeling for peptide identification. Analytical chemistry, 85(10), 5129-37. PMID: 23638792.

Hebert*, A. S., Merrill*, A. E., Bailey, D. J., Still, A. J., Westphall, M. S., Strieter, E. R., Pagliarini, D. J. & Coon, J. J. (2013). Neutron-encoded mass signatures for multiplexed proteome quantification. Nature methods, 10(4), 332-4. PMID: 23435260.