Nitin J. Karandikar, MD, PhD

Portrait
Chair and Department Executive Officer
Dr. Richard G. Lynch Chair in Experimental Pathology
Professor of Pathology

Contact Information

Office
C673 General Hospital
Iowa City, IA 52242
319-384-9609

Education

MBBS, Bachelor of Medicine and Surgery, B.J. Medical College, University of Poona
MD, Pathology, B.J. Medical College, University of Poona
PhD, Immunology and Molecular Pathogenesis Graduate Program, Northwestern University Medical School
Internship, B.J. Medical College, University of Poona
Resident, Anatomic and Clinical Pathology, B.J. Medical College, University of Poona
Resident, Clinical Pathology, University of Texas Southwestern Medical Center, Dallas
Fellow, Hematopathology, University of Texas Southwestern Medical Center, Dallas
Postdoctoral Fellow, Research in Immunology, University of Texas Southwestern Medical Center

Licensure and Certifications

State of Iowa Medical License - Iowa Board of Medicine
Hematology - American Board of Pathology
State of Texas Medical License - Texas Board of Medicine
Clinical Pathology - American Board of Pathology

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Immunology, Interdisciplinary Graduate Program in Molecular Medicine

Publications

Gupta, S., Karandikar, N. J., Ginader, T., Bellizzi, A. M. & Holman, C. J. (2018). Flow cytometric aberrancies in plasma cell myeloma and MGUS - correlation with laboratory parameters. Cytometry. Part B, Clinical cytometry. PMID: 29316245.

Itani, F. R., Sinha, S., Brate, A. A., Pewe, L. L., Gibson-Corley, K. N., Harty, J. T. & Karandikar, N. J. (2017). Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen. Scientific Reports, 7(1). DOI: 10.1038/s41598-017-01771-8.

Krasowski, M. D., Ford, B. A., Klutts, J. S., Jensen, C. S., Briggs, A. S., Robinson, R. A., Bruch, L. A. & Karandikar, N. J. (2017). Using Focused Laboratory Management and Quality Improvement Projects to Enhance Resident Training and Foster Scholarship. Academic pathology, 4, 2374289517722152. PMID: 28913416.

Blau, J., Wilford, J., Dane, S., Karandikar, N., Fuller, E., Jacobsmeier, D., Jans, M., Horning, E., Krasowski, M., Ford, B., Becker, K., Beranek, J. & Robinson, R. (2017). Implementation of epic beaker anatomic pathology at an academic medical center. Journal of Pathology Informatics, 8(1), 47. DOI: 10.4103/jpi.jpi_31_17.

Mohiuddin, I. H., Pillai, V., Baughman, E. J., Greenberg, B. M., Frohman, E. M., Crawford, M. P., Sinha, S. & Karandikar, N. J. (2016). Induction of regulatory T-cells from memory T-cells is perturbed during acute exacerbation of multiple sclerosis. Clinical immunology (Orlando, Fla.). PMID: 27154631.

Steussy, B., Lekostaj, J., Qian, Q., Rosenthal, N., Holman, C. J., Syrbu, S., Darbro, B., Bossler, A. & Karandikar, N. J. (2016). Leukemic Transdifferentiation of Follicular Lymphoma Into an Acute Histiocytic Leukemia in a 52-Year-Old Caucasian Woman. Laboratory Medicine, 47(2), 155-157. DOI: 10.1093/labmed/lmw011.

Krasowski, M. D., Wilford, J. D., Howard, W., Dane, S., Davis, S. R., Karandikar, N. J., Blau, J. L. & Ford, B. (2016). Implementation of Epic Beaker clinical pathology at an academic medical center. J Pathol Informatics, 7, 7. PMID: 26955505.

Gibson-Corley, K. N., Boyden, A. W. & Karandikar, N. J. (2016). A method for histopathological study of the multifocal nature of spinal cord lesions in murine experimental autoimmune encephalomyelitis. PeerJ.

Sinha, S., Boyden, A. W., Itani, F. R., Crawford, M. P. & Karandikar, N. J. (2015). CD8(+) T-cells as immune regulators of multiple sclerosis. Front Immunol, 6, 619. PMID: 26697014.

Ortega, S. B., Kashi, V. P., Cunnasamy, K., Franco, J. & Karandikar, N. J. (2015). Autoregulatory CD8 T cells depend on cognate antigen recognition and CD4/CD8 myelin determinants. Neurol Neuroimmunol Neuroinflamm, 2(6), e170. PMID: 26587555.

Sinha, S., Crawford, M. P., Ortega, S. B. & Karandikar, N. J. (2015). Multiparameter flow cytometric assays to quantify effector and regulatory T cell function in multiple sclerosis. J Mult Scler , 2(1), 130. PMID: 26137595.

Wang, L., Peters, J. M., Li, L., Karandikar, N. J., Koduru, P., Wang, H. Y. & Chen, W. (2014). Acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotype. Cytometry B Clin Cytom. PMID: 25302938.

Rakheja, D., Chen, K. S., Liu, Y., Shukla, A. A., Schmid, V., Chang, T., Khokhar, S., Wickiser, J. E., Karandikar, N. J., Malter, J. S., Mendell, J. T. & Amatruda, J. F. (2014). Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumors. Nature Communications, 2, 4802. PMID: 25190313.

Kashi, V. P., Ortega, S. B. & Karandikar, N. J. (2014). Neuroantigen-specific autoregulatory CD8+ T cells inhibit autoimmune demyelination through modulation of dendritic cell function. PLoS ONE, 9(8). PMID: 25144738.

Cunnusamy, K., Baughman, E. J., Franco, J., Ortega, S. B., Sinha, S., Chaudhary, P., Greenberg, B. M., Frohman, E. M. & Karandikar, N. J. (2014). Disease exacerbation of multiple sclerosis is characterized by loss of terminally differentiated autoregulatory CD8+ T cells. Clinical Immunology, 152(May-June), 115-126.

Sinha, S., Itani, F. R. & Karandikar, N. J. (2014). Immune regulation of multiple sclerosis by CD8+ T cells. Immunologic Research.

Ortega, S. B., Kashi, V. P., Tyler, A. F., Cunnusamy, K., Mendoza, J. P. & Karandikar, N. J. (2013). The disease-ameliorating function of autoregulatory CD8 T cells is mediated by targeting of encephalitogenic CD4 T cells in experimental autoimmune encephalomyelitis. Journal of Immunology, 191(1), 117-26. PMID: 23733879.

Tyler, A. F., Mendoza, J. P., Firan, M. & Karandikar, N. J. (2013). CD8+T cells are required for glatiramer acetate therapy in autoimmune demyelinating disease. PLoS One, 8(6), e66772. PMID: 23805274.

Ayers, C. L., Mendoza, J. P., Sinha, S., Cunnusamy, K., Greenberg, B. M., Frohman, E. M. & Karandikar, N. J. (2013). Modulation of immune function occurs within hours of therapy initiation for multiple sclerosis. Clinical Immunology, 147(2), 105-119. PMID: 23578552.

Gutierrez, T., Mayeux, J. M., Ortega, S. B., Karandikar, N. J., Li, Q. Z., Rakheja, D., Zhou, X. J. & Satterthwaite, A. B. (2013). IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn(-/-) mice. European journal of immunology, 43(2), 382-93. PMID: 23169140.

Greenberg, B. M., Graves, D., Remington, G., Hardeman, P., Mann, M., Karandikar, N. J., Stuve, O., Monson, N. & Frohman, E. (2012). Rituximab dosing and monitoring strategies in neuromyelitis optica patients: Creating strategies for therapeutic success. Multiple sclerosis, 18(7), 1022-6. PMID: 22261118.

Zaremba, C. M., Oliver, D., Cavalier, M., Fuda, F., Karandikar, N. J. & Chen, W. (2012). Distinct immunophenotype of early T-cell progenitors in T lymphoblastic leukemia/lymphoma may predict FMS-like tyrosine kinase 3 mutations. Annals of diagnostic pathology, 16(1), 16-20. PMID: 22050963.

Rakheja, D., Konoplev, S., Su, M., Wheeler, D., Muzny, D. M., Ruvolo, V. R., Collins, R., Karandikar, N. J., Andreeff, M., Medeiros, L. J. & Chen, W. (2011). High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei. British journal of haematology, 155(1), 125-8. PMID: 21480859.

Biegler, B. W., Yan, S. X., Ortega, S. B., Tennakoon, D. K., Racke, M. K. & Karandikar, N. J. (2011). Clonal composition of neuroantigen-specific CD8+ and CD4+ T-cells in multiple sclerosis. Journal of neuroimmunology, 234(2-Jan), 131-40. PMID: 21397340.

Ayers, C. L., Firan, M., Pillai, V., Lee, W. M. & Karandikar, N. J. (2011). Viral interactions with B-cells contribute to increased regulatory T-cells during chronic HCV infection. Viral immunology, 24(2), 119-29. PMID: 21449722.

Baughman, E. J., Mendoza, J. P., Ortega, S. B., Ayers, C. L., Greenberg, B. M., Frohman, E. M. & Karandikar, N. J. (2011). Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis. Journal of autoimmunity, 36(2), 115-24. PMID: 21257291.

Harp, C. T., Ireland, S., Davis, L. S., Remington, G., Cassidy, B., Cravens, P. D., Stuve, O., Lovett-Racke, A. E., Eagar, T. N., Greenberg, B. M., Racke, M. K., Cowell, L. G., Karandikar, N. J., Frohman, E. M. & Monson, N. L. (2010). Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFN-? production in response to myelin basic protein and myelin oligodendrocyte glycoprotein. European journal of immunology, 40(10), 2942-56. PMID: 20812237.

York, N. R., Mendoza, J. P., Ortega, S. B., Benagh, A., Tyler, A. F., Firan, M. & Karandikar, N. J. (2010). Immune regulatory CNS-reactive CD8+T cells in experimental autoimmune encephalomyelitis. Journal of autoimmunity, 35(1), 33-44. PMID: 20172692.

Tirado, C. A., Valdez, F., Klesse, L., Karandikar, N. J., Uddin, N., Arbini, A., Fustino, N., Collins, R., Patel, S., Smart, R. L., Garcia, R., Doolittle, J. & Chen, W. (2010). Acute myeloid leukemia with inv(16) with CBFB-MYH11, 3'CBFB deletion, variant t(9;22) with BCR-ABL1, and del(7)(q22q32) in a pediatric patient: case report and literature review. Cancer genetics and cytogenetics, 200(1), 54-9. PMID: 20513535.

Seegmiller, A. C., Garcia, R., Huang, R., Maleki, A., Karandikar, N. J. & Chen, W. (2010). Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas. Modern pathology: an official journal of the United States and Canadian Academy of Pathology, Inc, 23(7), 909-20. PMID: 20348878.

Tirado, C. A., Chen, W., Valdez, F., Karandikar, N. J., Arbini, A., Acevedo, I., Garcia, R., Davila, O., Smart, R. L., Matthews, E., Kirk, A. & Collins, R. H. (2010). Unusual presentation of myeloid sarcoma in a case of acute promyelocytic leukemia with a cryptic PML-RARA rearrangement involving multiple sites including the atrium. Cancer genetics and cytogenetics, 200(1), 47-53. PMID: 20513534.

Wang, H. Y., Fuda, F. S., Chen, W. & Karandikar, N. J. (2010). Notch1 in primary effusion lymphoma: a clinicopathological study. Modern pathology: an official journal of the United States and Canadian Academy of Pathology, Inc, 23(6), 773-80. PMID: 20348880.

Olteanu, H., Karandikar, N. J., Eshoa, C. & Kroft, S. H. (2010). Laboratory findings in CD4(+) large granular lymphocytoses. International journal of laboratory hematology, 32(1 Pt 1), e9-16. PMID: 20089001.

Pillai, V., Karandikar, N., Baughman, E., Mendoza, J. & Mohiuddin, I. (2010). Activation induced suppressive ability in human T cells revealed by a flow cytometric suppression assay. (Vols. 135). (Supplement), pp. S121. Clinical Immunology.

Qian, Y., Wei, C., Eun-Hyung Lee, F., Campbell, J., Halliley, J., Lee, J. A., Cai, J., Kong, Y. M., Sadat, E., Thomson, E., Dunn, P., Seegmiller, A. C., Karandikar, N. J., Tipton, C. M., Mosmann, T., Sanz, I. & Scheuermann, R. H. (2010). Elucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry data. Cytometry. Part B, Clinical cytometry, 78 Suppl 1, S69-82. PMID: 20839340.

Racke, M. K., Lovett-Racke, A. E. & Karandikar, N. J. (2010). The mechanism of action of glatiramer acetate treatment in multiple sclerosis. Neurology, 74 Suppl 1, S25-30. PMID: 20038760.

Cubillas, R., Kintner, K., Phillips, F., Karandikar, N. J., Thiele, D. L. & Brown, G. R. (2010). Tumor necrosis factor receptor 1 expression is upregulated in dendritic cells in patients with chronic HCV who respond to therapy. Hepatitis research and treatment, 2010, 429243. PMID: 21152182.

Seegmiller, A. C., Kroft, S. H., Karandikar, N. J. & McKenna, R. W. (2009). Characterization of immunophenotypic aberrancies in 200 cases of B acute lymphoblastic leukemia. American journal of clinical pathology, 132(6), 940-9. PMID: 19926587.

Fuda, F. S., Karandikar, N. J. & Chen, W. (2009). Significant CD5 expression on normal stage 3 hematogones and mature B Lymphocytes in bone marrow. American journal of clinical pathology, 132(5), 733-7. PMID: 19846815.

Chen, Y., Wu, H., Wang, S., Koito, H., Li, J., Ye, F., Hoang, J., Escobar, S. S., Gow, A., Arnett, H. A., Trapp, B. D., Karandikar, N. J., Hsieh, J. & Lu, Q. R. (2009). The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nature neuroscience, 12(11), 1398-406. PMID: 19838178.

Deisch, J., Fuda, F. B., Chen, W., Karandikar, N. J., Arbini, A. A., Zhou, X. J. & Wang, H. Y. (2009). Segmental tandem triplication of the MLL gene in an intravascular large B-cell lymphoma with multisystem involvement: a comprehensive morphologic, immunophenotypic, cytogenetic, and molecular cytogenetic antemortem study. Archives of pathology & laboratory medicine, 133(9), 1477-82. PMID: 19722759.

Maleki, A., Seegmiller, A. C., Uddin, N., Karandikar, N. J. & Chen, W. (2009). Bright CD38 expression is an indicator of MYC rearrangement. Leukemia & lymphoma, 50(6), 1054-7. PMID: 19455464.

Seegmiller, A. C., Karandikar, N. J., Kroft, S. H., McKenna, R. W. & Xu, Y. (2009). Overexpression of CD7 in classical Hodgkin lymphoma-infiltrating T lymphocytes. Cytometry. Part B, Clinical cytometry, 76(3), 169-74. PMID: 18956470.

del Pilar Martin, M., Cravens, P. D., Winger, R., Frohman, E. M., Racke, M. K., Eagar, T. N., Zamvil, S. S., Weber, M. S., Hemmer, B., Karandikar, N. J., Kleinschmidt-DeMasters, B. K. & Stüve, O. (2008). Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab. Archives of Neurology, 65(12), 1596-603. PMID: 18852339.

Frohman, E. M., Eagar, T., Monson, N., Stuve, O. & Karandikar, N. J. (2008). Immunologic mechanisms of multiple sclerosis. Neuroimaging clinics of North America, 18(4), 577-88, ix. PMID: 19068403.

Wang, H. Y., Karandikar, N. J., Payne, D., Maleki, A., Schultz, B. A., Collins, R. & McKenna, R. W. (2008). A 3-way collision tumor of the upper respiratory tract: a composite of 2 immunophenotypically distinct mantle cell lymphomas and a plasmacytoma. Human pathology, 39(5), 781-7. PMID: 18284935.

Maftoun-Banankhah, S., Maleki, A., Karandikar, N. J., Arbini, A. A., Fuda, F. S., Wang, H. Y. & Chen, W. (2008). Multiparameter flow cytometric analysis reveals low percentage of bone marrow hematogones in myelodysplastic syndromes. American journal of clinical pathology, 129(2), 300-8. PMID: 18208811.

Pillai, V., Karandikar, N. J. (2008). Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity. Blood, 111(1), 463-4; author reply 464-6. PMID: 18156502.

Kroft, S. H., Karandikar, N. J. (2008). Flow cytometric analysis of acute leukemias, myelodysplastic syndromes and myeloproliferative disorders. In D. F. Keren , J. P. McCoy , J. L. Carey (Eds.) Flow Cytometry in Clinical Diagnosis; 4th edition. pp. 167-214. ASCP.

Olteanu, H., Wang, H. Y., Chen, W., McKenna, R. W. & Karandikar, N. J. (2008). Immunophenotypic studies of monoclonal gammopathy of undetermined significance. BMC clinical pathology, 8, 13. PMID: 19040735.

Wang, H. Y., Wilson, K. S., McKenna, R. W., Xu, Y. & Karandikar, N. J. (2007). An extranodal nasal natural killer/T-cell lymphoma with isochromosome 7q10 as the sole cytogenetic aberration was initially diagnosed via bone marrow biopsy. Archives of pathology & laboratory medicine, 131(11), 1709-14. PMID: 17979491.

Pillai, V., Karandikar, N. J. (2007). Human regulatory T cells: a unique, stable thymic subset or a reversible peripheral state of differentiation?. Immunology letters, 114(1), 15-Sep. PMID: 17945352.

Sathe, A., Ortega, S. B., Mundy, D. I., Collins, R. H. & Karandikar, N. J. (2007). In vitro methotrexate as a practical approach to selective allodepletion. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 13(6), 644-54. PMID: 17531774.

Pillai, V., Lee, W. M., Thiele, D. L. & Karandikar, N. J. (2007). Clinical responders to antiviral therapy of chronic HCV infection show elevated antiviral CD4+ and CD8+ T-cell responses. Journal of viral hepatitis, 14(5), 318-29. PMID: 17439521.

Averill, L., Lee, W. M. & Karandikar, N. J. (2007). Differential dysfunction in dendritic cell subsets during chronic HCV infection. Clinical immunology (Orlando, Fla.), 123(1), 40-9. PMID: 17239662.

Pillai, V., Ortega, S. B., Wang, C. K. & Karandikar, N. J. (2007). Transient regulatory T-cells: a state attained by all activated human T-cells. Clinical immunology (Orlando, Fla.), 123(1), 18-29. PMID: 17185041.

Seegmiller, A. C., Xu, Y., McKenna, R. W. & Karandikar, N. J. (2007). Immunophenotypic differentiation between neoplastic plasma cells in mature B-cell lymphoma vs plasma cell myeloma. American journal of clinical pathology, 127(2), 176-81. PMID: 17210522.

Chen, W., Karandikar, N. J., McKenna, R. W. & Kroft, S. H. (2007). Stability of leukemia-associated immunophenotypes in precursor B-lymphoblastic leukemia/lymphoma: a single institution experience. American Journal of Clinical Pathology, 127(1), 39-46. PMID: 17145625.

Olteanu, H., Karandikar, N. J., McKenna, R. W. & Xu, Y. (2006). Differential usefulness of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and bone marrow. American Journal of Clinical Pathology, 126(5), 781-8. PMID: 17050075.

Biegler, B. W., Yan, S. X., Ortega, S. B., Tennakoon, D. K., Racke, M. K. & Karandikar, N. J. (2006). Glatiramer acetate (GA) therapy induces a focused, oligoclonal CD8+ T-cell repertoire in multiple sclerosis. Journal of Neuroimmunology, 180(2-Jan), 159-71. PMID: 16935352.

Ratts, R. B., Lovett-Racke, A. E., Choy, J., Northrop, S. C., Hussain, R. Z., Karandikar, N. J. & Racke, M. K. (2006). CD28-CD57+ T cells predominate in CD8 responses to glatiramer acetate. Journal of Neuroimmunology, 178(2-Jan), 117-29. PMID: 16837065.

Ratts, R. B., Karandikar, N. J., Hussain, R. Z., Choy, J., Northrop, S. C., Lovett-Racke, A. E. & Racke, M. K. (2006). Phenotypic characterization of autoreactive T cells in multiple sclerosis. Journal of Neuroimmunology, 178(2-Jan), 100-10. PMID: 16901549.

Xu, Y., McKenna, R. W., Wilson, K. S., Karandikar, N. J., Schultz, R. A. & Kroft, S. H. (2006). Immunophenotypic identification of acute myeloid leukemia with monocytic differentiation. Leukemia: official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 20(7), 1321-4. PMID: 16642046.

Tennakoon, D. K., Mehta, R. S., Ortega, S. B., Bhoj, V., Racke, M. K. & Karandikar, N. J. (2006). Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950), 176(11), 7119-29. PMID: 16709875.

Chen, W., Kesler, M. V., Karandikar, N. J., McKenna, R. W. & Kroft, S. H. (2006). Flow cytometric features of angioimmunoblastic T-cell lymphoma. Cytometry. Part B, Clinical cytometry, 70(3), 142-8. PMID: 16572417.

Xu, Y., McKenna, R. W., Karandikar, N. J., Pildain, A. J. & Kroft, S. H. (2005). Flow cytometric analysis of monocytes as a tool for distinguishing chronic myelomonocytic leukemia from reactive monocytosis. American Journal of Clinical Pathology, 124(5), 799-806. PMID: 16203279.

Frohman, E. M., Filippi, M., Stuve, O., Waxman, S. G., Corboy, J., Phillips, J. T., Lucchinetti, C., Wilken, J., Karandikar, N. J., Hemmer, B., Monson, N., De Keyser, J., Hartung, H., Steinman, L., Oksenberg, J. R., Cree, B. A., Hauser, S. & Racke, M. K. (2005). Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Archives of Neurology, 62(9), 1345-56. PMID: 16157741.

Frohman, E. M., Filippi, M., Stuve, O., Waxman, S. G., Corboy, J., Phillips, J. T., Lucchinetti, C., Wilken, J. & Karandikar, N. J. (2005). Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Archives of Neurology,(62), 1345-56.

Karandikar, N. J., Racke, M. K. (2005). Glatiramer acetate therapy: The plot thickens. Archives of Neurology,(62), 858-9.

Alfardan, J. M., Kroft, S. H., Fuda, F. S., Xu, Y., McKenna, R. W. & Karandikar, N. J. (2005). Immunophenotypic comparison of peripheral blood stem cells, normal bone marrow blasts and leukemic myeloid blasts. (18), pp. 220A 1025 Suppl. 1. Modern Pathology.

Fuda, F. S., Kroft, S. H., Alfardan, J. M., Xu, Y., McKenna, R. W. & Karandikar, N. J. (2005). Myeloperoxidase expression differentiates leukemic from non-leukemic blasts. (18), pp. 230A-230A 1068 Suppl. 1. Modern Pathology.

Karandikar, N. J., Kroft, S. H., Yegappan, S., Rogers, B. B., Aquino, V. M., Lee, K. M., Kumar, V., Guenaga, F. J., Jaffe, E. S., Douek, D. C. & McKenna, R. W. (2004). Unusual immunophenotype of CD8+ T cells in familial hemophagocytic lymphohistiocytosis. Blood, 104(7), 2007-9. PMID: 15205266.

Kroft, S. H., Asplund, S. L., McKenna, R. W. & Karandikar, N. J. (2004). Haematogones in the peripheral blood of adults: a four-colour flow cytometry study of 102 patients. British Journal of Haematology, 126(2), 209-12. PMID: 15238141.

Eagar, T. N., Turley, D. M., Padilla, J., Karandikar, N. J., Tan, L., Bluestone, J. A. & Miller, S. D. (2004). CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance. Journal of Immunology (Baltimore, Md. : 1950), 172(12), 7442-50. PMID: 15187122.

Crawford, M. P., Yan, S. X., Ortega, S. B., Mehta, R. S., Hewitt, R. E., Price, D. A., Stastny, P., Douek, D. C., Koup, R. A., Racke, M. K. & Karandikar, N. J. (2004). High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood, 103(11), 4222-31. PMID: 14976054.

Rawal, A., Sarode, R., Curtis, B. R., Karandikar, N. J., Friedman, K. & Rogers, Z. R. (2004). Acquired Glanzmann's thrombasthenia as part of multiple-autoantibody syndrome in a pediatric heart transplant patient. The Journal of Pediatrics, 144(5), 672-4. PMID: 15127012.

Brenchley, J. M., Karandikar, N. J., Betts, M. R., Ambrozak, D. R., Hill, B. J., Crotty, L. E., Casazza, J. P., Kuruppu, J., Migueles, S. A., Connors, M., Roederer, M., Douek, D. C. & Koup, R. A. (2003). Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood, 101(7), 2711-20. PMID: 12433688.

Karandikar, N. J., Hotchkiss, E. C., Mckenna, R. W. & Kroft, S. H. (2002). Transient stress lymphocytosis: an immunophenotypic characterization of the most common cause of newly identified adult lymphocytosis in a tertiary hospital. American Journal of Clinical Pathology, 117(5), 819-25. PMID: 12090434.

Eagar, T. N., Karandikar, N. J., Bluestone, J. A. & Miller, S. D. (2002). The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance. European journal of immunology, 32(4), 972-81. PMID: 11920563.

Douek, D. C., Betts, M. R., Brenchley, J. M., Hill, B. J., Ambrozak, D. R., Ngai, K. L., Karandikar, N. J., Casazza, J. P. & Koup, R. A. (2002). A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape. Journal of Immunology (Baltimore, Md. : 1950), 168(6), 3099-104. PMID: 11884484.

Karandikar, N. J., Crawford, M. P., Yan, X., Ratts, R. B., Brenchley, J. M., Ambrozak, D. R., Lovett-Racke, A. E., Frohman, E. M., Stastny, P., Douek, D. C., Koup, R. A. & Racke, M. K. (2002). Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis. The Journal of Clinical Investigation, 109(5), 641-9. PMID: 11877472.

Racke, M. K., Lovett-Racke, A. E. & Karandikar, N. J. (2002). Myelin-reactive T cells and their regulation in multiple sclerosis. Neuroscience News,(4), 29-38.

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