Nephrology, Dialysis and Transplantation

Carla Nester portrait
Carla M. Nester, MD, MSA
Division Director

The Division of Nephrology, Dialysis, and Transplantation is the only pediatric nephrology program in the state of Iowa with dialysis and transplant capabilities for all pediatric age groups. It also has the only pediatric liver dialysis (MARS) capabilities in the country, and can perform filter based plasma exchange. The UI Children’s Hospital Pediatric Dialysis Center opened in late 2010.

The multidisciplinary team of experts including pediatric nephrologists, specialized nurses, social workers, and nutritionists, develop protocols and standardized evidenced based treatment approaches. U.S. News and World Report 2012-2013 Best Children’s Hospitals ranked UI Children's Hospital's nephrology services in the top 20 in the country.

Research in the division includes NIH-funded clinical trials that are nationally and internationally recognized. The faculty research includes exciting new developments and evidence for hemodynamic monitoring, fluid management, dialysis timing, and extracorporeal support for critically ill patients. Many collaborative research opportunities exist close at home and throughout the country.

The division is home to an outstanding ACGME approved fellowship program. Opportunities are available to study rare renal diseases such as Dense Deposit Disease and atypical HUS.

Key research interests in the division include:

  • acute renal injury or failure
  • hyperkalemia
  • proteinuria
  • congenital abnormalities of the urinary tract
  • pediatric urinary tract infections
  • continuous renal replacement therapies in very low birth weight infants
  • urinary metabolomic markers of aminoglycoside nephrotoxicity in newborn rats
  • atypical haemolytic uraemic syndrome