Recent Publications

Perito ER, Palermo TM, Pohl JF, Mascarenhas M, Abu-El-Haija M, et al…, Uc A. Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis.  J Pediatr Gastroenterol Nutr. 2019 Sep 20. doi: 10.1097/MPG.0000000000002502. [Epub ahead of print]

Lin TK, Fishman DS, Giefer MJ, Liu QY, Troendle D, Werlin S, Lowe ME, Uc A. Functional Pancreatic Sphincter Dysfunction in Children: Recommendations for Diagnosis and Management.  J Pediatr Gastroenterol Nutr. 2019 Sep 20. doi: 10.1097/MPG.0000000000002515. [Epub ahead of print]

Li SC, Fuhlbrigge RC, Laxer RM, Pope E, Ibarra MF, Stewart K, Mason T, Becker ML, Hong S, Dedeoglu F, Torok KS, Egla Rabinovich C, Ferguson PJ, Punaro M, Feldman BM, Andrews T, Higgins GC, and For the CARRA Registry Investigators.  Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study.  Pediatric Rheumatology (2019) 17:43.

Isoldi S, Belsha D, Yeop I, Uc A, Zevit N, Mamula P, Loizides AM, Tabbers M, Cameron D, Day AS, Abu-El-Haija M, Chongsrisawat V, Briars G, Lindley KJ, Koeglmeier J, Shah N, Harper J, Syed SB, Thomson M.  Diagnosis and management of children with Blue Rubber Bleb Nevus Syndrome: A multi-center case series.  Dig Liver Dis. 2019 Jul 26. pii: S1590-8658(19)30679-6. doi: 10.1016/j.dld.2019.04.020. [Epub ahead of print]

Girsch JH, Walters K, Jackson W, Grose C.  Progeny Varicella-Zoster Virus Capsids Exit the Nucleus but Never Undergo Secondary Envelopment during Autophagic Flux Inhibition by Bafilomycin A1.  J Virol. 2019 Aug 13;93(17). pii: e00505-19. doi: 10.1128/JVI.00505-19. Print 2019 Sep 1.

Cifra CL, Houston M, Otto A, Kamath SS.  Prompting Rounding Teams to Address a Daily Best Practice Checklist in a Pediatric Intensive Care Unit.  Jt Comm J Qual Patient Saf. 2019 Aug;45(8):543-551. doi: 10.1016/j.jcjq.2019.05.012. Epub 2019 Jul 17.

Elgin TG, Fricke EM, Gong H, Reese J, Mills DA, Kalantera KM, Underwood MA, McElroy SJ.  Fetal exposure to maternal inflammation interrupts murine intestinal development and increases susceptibility to neonatal intestinal injury.  Dis Model Mech. 2019 Sep 19. pii: dmm.040808. doi: 10.1242/dmm.040808. [Epub ahead of print]

Rutherford HJV, Xu J, Worhunsky PD, Zhang R, Yip SW, Morie KP, Calhoun VD, Kim S, Strathearn L, Mayes LC, Potenza MN (2019). Gradient Theories of Brain Activation: a Novel Application to Studying the Parental Brain.  Current Behavioral Neuroscience Reports. doi:10.1007/s40473-019-00182-5

Nguyen AJ, Hoyer E, Rajhans P, Strathearn L, & Kim S. (2019). A tumultuous transition to motherhood: Altered brain and hormonal responses in mothers with postpartum depression. J Neuroendocrinol, 00, e12794

Bellin MD, Lowe M, Zimmerman MB, Wilschanski M, Werlin S, Troendle DM, Shah U, Schwarzenberg SJ, Pohl JF, Perito E, Ooi CY, Nathan JD, Morinville VD, McFerron BA, Mascarenhas MR, Maqbool A, Liu Q, Lin TK, Husain SZ, Himes R, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Freedman SD, Fishman DS, Barth B, Abu-El-Haija M, Uc A. Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data from the INSPPIRE Cohort.  J Pediatr Gastroenterol Nutr. 2019 Aug 27. doi: 10.1097/MPG.0000000000002482. [Epub ahead of print]

Singh SB, McLearn-Montz AJ, Milavetz F, Gates LK, Fox C, Murry LT, Sabus A, Porterfield HS, Fischer AJ.  Pathogen acquisition in patients with cystic fibrosis receiving ivacaftoror lumacaftor/ivacaftor.  Pediatr Pulmonol. 2019 Apr 22. doi: 10.1002/ppul.24341. [Epub ahead of print].

Ringold S, Angeles-Han ST, Beukelman T, Lovell D, Cuello CA, Becker ML, Colbert RA, Feldman BM, Ferguson PJ, et al. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis.  Arthritis Care & Research. 2019. DOI 10.1002/acr.23870.

Angeles-Han ST, Ringold S, Beukelman T, Lovell D, Cuello CA, Becker ML, Colbert RA, Feldman BM, Holland GN, Ferguson, PJ, et al.  2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis–Associated Uveitis.  Arthritis Care & Research. 2019 DOI 10.1002/acr.23871.

D’Cunha R, Widness JA, Yan X, Schmidt RL, Veng-Pedersen P, An G. A Mechanism-Based Population Pharmacokinetics Model of Erythropoietin in Premature Infants and Healthy Adults Following Multiple Intravenous Doses.  Journal of Clinical Pharmacology.  2019, 59(6) 835–846.

Abe K, Cox A, Takamatsu N, Velez G, Laxer RM, Tse SML, Mahajan VB, Bassuk AG, Fuchs H, Ferguson PJ, de Angelis MH.  Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans.  PNAS2019.

Liu QY, Abu-El-Haija M, Husain SZ, Barth B, Bellin M, Fishman DS, Freedman SD, Gariepy CE, Giefer MJ, Gonska T, Heyman MB, Himes R, Lin TK, Maqbool A, Mascarenhas M, McFerron BA, Morinville VD, Nathan JD, Ooi CY, Perito ER, Pohl JF, Rhee S, Schwarzenberg SJ, Shah U, Troendle D, Werlin SL, Wilschanski M, Zimmerman MB, Lowe ME, Uc A.  Risk Factors for Rapid Progression From Acute Recurrent to Chronic Pancreatitis in Children: Report From INSPPIRE.  J Pediatr Gastroenterol Nutr. 2019 May 23. doi: 10.1097/MPG.0000000000002405. [Epub ahead of print].

Caplan MS, Underwood MA, Modi N, Patel R, Gordon PV, Sylovester KG, McElroy S, Manzoni P, Gephart S, Chwals WJ, Turner MA, Davis JM. Necrotizing Enterocolitis Workgroup of the International Neonatal Consortium∗  Necrotizing Enterocolitis: Using Regulatory Science and Drug Development to Improve Outcomes.  J Peds. 2019. Published online 22 June 2019.

Hebert A, Lavoie PM, Giesinger RE, Ting JY, Finan E, Singh Y, deBoode W, Kluckow M, Mertens L, McNamara PJ.  Evolution of Training Guidelines for Echocardiography Performed by the Neonatologist: Toward Hemodynamic Consultation.  Journal of the American Society of Echocardiography. June 2019. 

Herold KC, Bundy BN, Long A, Bluestone JA, DiMeglio LA, Dufort MJ, Tsalikian E, et al. An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.  NEJM. 2019. DOI: 10.1056/NEJMoa1902226.

Xu, Guifeng, Strathearn, Lane, & Bao, Wei. (2019).  Caution About Displaying State-Level Differences in the Prevalence of Autism Spectrum Disorder—Reply. Caution About Displaying State-Level Differences in the Prevalence of Autism Spectrum Disorder—ReplyLetters.   JAMA Pediatrics. doi:10.1001/jamapediatrics.2019.1724.

Rajhans, P., Goin-Kochel, R. P., Strathearn, L., & Kim, S. (2019).  It Takes Two! Exploring Sex Differences in Parenting Neurobiology and Behavior.   J Neuroendocrinol, e12721. doi:10.1111/jne.12721.

Cox AJ, Grady ‘F, Velez G, Mahajan VB, Ferguson PJ, Kitchen A, Darbro BW, Bassuk AG. In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth.  Genetics Research 2019;101:8. DOI: Published online by Cambridge University Press: 13 June 2019.

Saloman JL, Albers KM, Cruz-Monserrate Z, Davis BM, Edderkaoui M, Eibl G, Epouhe AY, Gedeon JY, Gorelick FS, Grippo PJ, Groblewski GE, Husain SZ, Lai KKY, Pandol SJ, Uc A, Wen L, Whitcomb DC.  Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer.  Pancreas. 2019 Jul;48(6):759-779. doi: 10.1097/MPA.0000000000001335.

Rebecca Benson, MD, PhD.  Quoted in an article, “Ethical Concerns When Pediatric Palliative Care Patients Visit ED’s.”  In Medical Ethics Advisor, July 2019. 35;7:73-84. ISSN 0886-0653. Relias Media.

Harmoney K, Mobley EM, Gilbertson-White S, Brogden NK, Benson RJ. Differences in Advance Care Planning and Circumstances of Death for Pediatric Patients Who Do and Do Not Receive Palliative Care Consults: A Single-Center Retrospective Review of All Pediatric Deaths from 2012 to 2016.  Journal of Palliative Medicine. 2019. doi: 10.1089/jpm.2019.0111. 

Topjian AA, de Caen A, Wainwright MS, Abella BS, Abend NS, Atkins DL, Bembea MM, Fink EL, Guerguerian AM, Haskell SE, Kilgannon JH, Lasa JJ, Hazinski MF; American Heart Association Emergency Cardiovascular Care Science Subcommittee; American Heart Association Emergency Cardiovascular Care Pediatric Emphasis Group; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Genomic and Precision Medicine; and Stroke Council.  Pediatric Post-Cardiac Arrest Care: A Scientific Statement From the American Heart Association.  Circulation2019 June 27. Doi:10.1161/CIR.0000000000000697 

Curtis VA, Allen DB.  Male Pubertal Timing – Boys Will be Men, but When?  JAMA Pediatr. Published online July 22, 2019. doi:10.1001/jamapediatrics.2019.2306.

Graber A, O’Brien M.  The Promise of Accountable Care Organizations:  The Code, Reimbursement, and an Ethical No-Win Situation for Behavior Analysts.  Behavior Analysis in Practice.  March 2019, Volume 12, Issue 1, pp 247-254.

Leyser, M. A multilevel-based research framework on congenital Zika syndrome  Pediatr Res. 2019 Feb 21. doi: 10.1038/s41390-019-0349-0. [Epub ahead of print]

Leyser, M.  Children Born With Congenital Zika Syndrome Display Atypical Gross Motor Development and a Higher Risk for Cerebral Palsy  JChild Neurol. 2019 Feb;34(2):81-85. doi: 10.1177/0883073818811234. Epub 2018 Nov 13.

Lynch, DR, Hauser, L, McCormick, A, Wells, M, Dong, YN, McCormack, S , Schadt, Kim, Perlman, S, Subramony, SH, Mathews, KD, Brocht, A. Ball, J, Perdok, R, Grahn, A, Vescio, T, Sherman, JW, Farmer, JM.  Randomized, double‐blind, placebo‐controlled study of interferon‐γ 1b in Friedreich Ataxia  Annals of Clinical and Translational Neurology. 2019.doi: 10.1002/acn3.731 

Gonorazky, HD, Naumenko, S, Ramani, AK, Nelakuditi, V,  Machouri, P, Wang, P, Kao, D, Ohri, K, Viththiyapaskaran, S, Tarnopolsky, MA, Mathews, KD, Moore, S, Osorio, AN, Villanova, D,  Kemaladewi, DU, Cohn, RD, Brudno, M, Dowling, JJ.  Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease  Am J Hum Gen. 2019. 104.1-18.

Lee, AJ, Jones, KA, Butterfield, RJ, Cox, MO, Konersman, CG, Grosmann, C, Abdenur, JE, Boyer, M, Beson, B, Wang, C, Dowling, JJ, Gibbons, MA, Ballard, A, Janas, JS, Leshner, RT, Donkervoort, S, B¨onnemann, CG, Malicki, DM, Weiss, RB, Moore, SA, and Mathews, KD. Clinical, genetic, and pathologic characterization of FKRP Mexican founder mutation c.1387A>G  Neurol Genet 2019;5:e315. doi:10.1212/NXG.0000000000000315

Conway, KM, Eichinger, K, Trout, C, Romitti, PA, Mathews, KD, Pandya, SK.  Muscular Dystrophy Surveillance, Tracking and Research Network (MD STARnet).  Needs management in families affected by childhood-onsetdystrophinopathies.SAGE Open Medicine. 2019. 7, 1-11.

Grover AS, Freeman AJ, Abu-El-Haija M, Eisses JF, Gardner TB, Liu QY, Lowe ME, Nathan JD, Palermo TM, Singh VK, Trout AT, Uc A, Husain SZ, Morinville VD.  Updates in Pediatric Pancreatology: Proceedings of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Frontiers in Pediatric PancreatologySymposium.J Pediatr Gastroenterol Nutr. 2019 Feb;68(2):e27-e33. doi: 10.1097/MPG.0000000000002186

Schwarzenberg SJ, Uc A, Zimmerman B, Wilschanski M, Wilcox CM, Whitcomb DC, Werlin SL, Troendle D, et al. Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors  J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):566-573. doi: 10.1097/MPG.0000000000002279.

Sellers ZM, Dike C, Zhang KY, Giefer MJ, Uc A, Abu-El-Haija M.  Unified Treatment Algorithm and Admission Order Set for Pediatric Acute Pancreatitis. J Pediatr Gastroenterol Nutr. 2019 Mar 26. doi: 10.1097/MPG.0000000000002341. [Epub ahead of print]

Arthur CM, Nalbant D, Feldman HA, Saeedi BJ, Matthews J, Robinson BS, Kamili NA, Bennett A, Cress GA, Sola-Visner M, Jones RM, Zimmerman MB, Neish AS, Patel RM, Nopoulos P, Georgieff MK, Roback JD, Widness JA, Josephson CD, Stowell SR.  Anemia induces gut inflammation and injury in an animal model of preterm infants  Transfusion. 2019 Mar 21. doi: 10.1111/trf.15254. [Epub ahead of print]

Brumbaugh JE, Hansen NI, Bell EF, Sridhar A, Carlo WA, Hintz SR, Vohr BR, Colaizy TT, Duncan AF, Wyckoff MH, Baack ML, Rysavy MA, DeMauro SB, Stoll BJ, Das A, Higgins RD, for the National Institute of Child Health and Human Development Neonatal Research Network. Outcomes of Extremely Preterm Infants With Birth Weight Less Than 400 g.  JAMA Pediatr. Published online March 25, 2019. doi:10.1001/jamapediatrics.2019.0180

Rysavy MA, Ehret DEY.  Extremely Preterm Birth Outcomes in Sweden  JAMA. 2019;321(12):1163-1164. doi:10.1001/jama.2019.2020 

Verbsky J, Ferguson P in P. J. Hashkes et al. (eds.), Textbook of Autoinflammation. Genetic Causes of Inflammatory Bone Disease

Sun X, Yi Y, Liang B, Yang Y, He N, Ode KL, Uc A, Wang K, Gibson-Corley KN, Engelhardt JF, Norris AW.  Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin J Cyst Fibros. 2019 Feb 6. pii: S1569-1993(19)30016-5. doi: 10.1016/j.jcf.2019.01.010. [Epub ahead of print]

Uc A, Husain SZ.  Pancreatitis in Children  Gastroenterology. 2019 Feb 1. pii: S0016-5085(19)30352-X. doi: 10.1053/j.gastro.2018.12.043. [Epub ahead of print] 

J. Glykys, E. Duquette, N. Rahmati, et al. Mannitol decreases neocortical epileptiform activity during early brain development via cotransport of chloride and water,  Neurobiology of Disease,

Xu, G., Strathearn, L., Liu, B., O’Brien, M., Kopelman, T. G., Snetselaar, L. G., & Bao, W. (2018).  Prevalence and Treatment Patterns of Autism Spectrum Disorder in the United States, 2016.  JAMA Pediatrics.  2018 Dec 3. doi: 10.1001/jamapediatrics.2018.4208. [Epub ahead of print] 

Iyengar U, Rajhans P, Fonagy P, Strathearn L, & Kim S.  Unresolved Trauma and Reorganization in Mothers: Attachment and Neuroscience Perspectives. Frontiers in Psychology, 2019 10(110), 1-9.

Brueggeman L, Sturgeon ML, Martin RM, Grossbach AJ, Nagahama Y, Zhang A, Howard MA III, Kawasaki H, Wu S, Cornell RA, Michaelson JJ, Bassuk AG.  Drug repositioning in epilepsy reveals novel anti-seizure candidates. Annals of Clinical and Translational Neurology. First published: 11 December 2018.

Machlab DA, Velez G, Bassuk AG, Mahajan VB. ProSave: an application for restoring quantitative data to manipulated subsets of protein lists.  Source Code Biol Med. 2018 Nov 12;13:3. doi: 10.1186/s13029-018-0070-0. eCollection 2018. PubMed PMID: 30459825; PubMed Central PMCID: PMC6233572.

Tang PH, Velez G, Tsang SH, Bassuk AG, Mahajan VB.  VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site. Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):282-293. doi: 10.1167/iovs.18-25624. PubMed PMID: 30657523.

Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC.  The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation.  Hum Mol Genet. 2019 Jan 25. doi: 10.1093/hmg/ddz010. [Epub ahead of print] PubMed PMID: 30689861.

Moodley A, Swanson J, Grose C, Bonthius DJ.  Severe Herpes Zoster Following Varicella Vaccination in Immunocompetent Young Children.  Journal of Child Neurology. 2019 Jan 10:883073818821498. doi: 10.1177/0883073818821498. [Epub ahead of print]

Chatmethakul T, Roghair RD.  Risk of hypertension following perinatal adversity: IUGR and prematurity  Journal of Endocrinology, published online 1/18/19

Fischer AJ, Pino-Argumedo MI, Hilkin BM, Shanrock CR, Gansemer ND, Chaly AL, Zarei K, Allen PD, Ostedgaard LS, Hoffman EA, Stoltz DA, Welsh MJ, Alaiwa MHA.  Mucus strands from submucosal glands initiate mucociliary transport of large particles.  JCI Insight. 2019 Jan 10;4(1). pii: 124863. doi: 10.1172/jci.insight.124863. [Epub ahead of print] 

Failure to Provide Adequate Palliative Care May Be Medical Neglect.  Levy C, Weeks KS, Benson RJ, Miller JM, Higgins J, Deutsch SA, Lantos JD.  Pediatrics. 2019 Oct;144(4). pii: e20183939. doi: 10.1542/peds.2018-3939. Epub 2019 Sep 4.

Impaired Right Ventricular Performance is Associated with Adverse Outcome Following Hypoxic Ischemic Encephalopathy.  Giesinger RE, El Shahed AI, Castaldo MP, Breatnach CR, Chau V, Whyte HE, El-Khuffash A, Mertens L, McNamara PJ.  Am J Respir Crit Care Med. 2019 Jun 28. doi: 10.1164/rccm.201903-0583OC. [Epub ahead of print]

Pathways Relating the Neurobiology of Attachment to Drug Addiction.  Strathearn L, Mertens CE, Mayes L, Rutherford H, Rajhans P, Xu G, Potenza MN, Kim S.  Front Psychiatry, 08 November 2019 |

Updates to referring physicians regarding critically ill children admitted to a pediatric intensive care unit: A state-wide survey [published online ahead of print October 25, 2019]. Cifra CL, Tigges CR, Miller SL, Herwaldt LA, Singh H.  Diagnosis. doi:10.1515/dx-2019-0048.  Also presented as a platform and was awarded Best Quality Improvement Abstract at the recent American Academy of Pediatrics (Section on Critical Care) National Conference 2019

Precision Medicine in Pancreatic Disease-Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.  Lowe ME, Andersen DK, Caprioli RM, Choudhary J, Cruz-Monserrate Z, Dasyam AK, Forsmark CE, Gorelick FS, Gray JW, Haupt M, Kelly KA, Olive KP, Plevritis SK, Rappaport N, Roth HR, Steen H, Swamidass SJ, Tirkes T, Uc A, Veselkov K, Whitcomb DC, Habtezion A.  Pancreas. 2019 Nov/Dec;48(10):1250-1258. doi: 10.1097/MPA.0000000000001412.

“Handbook of Cognitive Behavioral Therapy for Pediatric Medical Conditions”  Jennifer Paternostro, PhD.  Co-editor, and co-authored 4 chapters within the book.

An evaluation of resurgence following functional communication training conducted in alternative antecedent contexts via telehealth. Suess AN, Schieltz KM, Wacker DP, Detrick J, Podlesnik CA.  J Exp Anal Behav. 2019 Oct 16. doi: 10.1002/jeab.551. [Epub ahead of print].

Wiskott-Aldrich syndrome protein senses irradiation-induced DNA damage to coordinate the cell-protective Golgi dispersal response in human T and B lymphocytes.  Wen KK, Han SS, Vyas YM.  J Allergy Clin Immunol. 2019 Oct 8. pii: S0091-6749(19)31263-1. doi: 10.1016/j.jaci.2019.09.026. [Epub ahead of print].  Impact Factor 14.11