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John Reho, PhD

Address: 2-200 BSB
Phone: (319) 335-7895
Email: john-reho@uiowa.edu

Mentor: Kamal Rahmouni, PhD

PhD Institution: University of Akron, Akron, OH, 2012

Research Description

Role of mTOR Signaling in the Endothelium

Awards

  • APS-Cardiovascular Section Research Recognition Awardee, 2017
  • American Heart Association Postdoctoral Fellowship, 2016-2018

Publications

  1. Reho JJ and Rahmouni K.:  Oxidative and Inflammatory Signals in Obesity-associated Vascular Abnormalities. Clin Sci (Lond). 131(14):1689-1700, 2017.  PMID: 28667067
  2. Chapleau MW, Rotella D, Reho J, Rahmouni K, Stauss HM.: Chronic Vagal Nerve Stimulation Prevents High-Salt Diet-Induced Endothelial Dysfunction and Aortic Stiffening in Stroke-Prone Spontaneously Hypertensive Rats. Am J Physiol Heart Circ Physiol 311(1):H276-85, 2016.  PMCID: PMC4967207
  3. Reho JJ, Kenchegowda D, Asico LD, Fisher SA.:  A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading. Am J Physiol Heart Circ Physiol 310(11):H1715-24, 2016.  PMCID: PMC4935519
  4. Reho JJ, Fisher SA.:  The stress of maternal separation causes misprogramming in the postnatal maturation of rat resistance arteries. Am J Physiol Heart Circ Physiol 309(9):H1468-78, 2015.  PMCID: PMC4666972
  5. Reho JJ, Shetty A, Dippold RP, Mahurkar A, Fisher SA.:  Unique gene program of rat small resistance mesenteric arteries as revealed by deep RNA sequencing.  Physiol Rep. 3(7):e12450, 2015.  PMCID: PMC4552530
  6. Reho JJ, Zheng X, Asico LD, Fisher SA.:  Redox signaling and splicing dependent change in myosin phosphatase underlie early versus late changes in NO vasodilator reserve in a mouse LPS model of sepsis. Am J Physiol Heart Circ Physiol 308(9):H1039-50, 2015.  PMCID: PMC4551119
  7. Zheng X, Reho JJ, Wirth B, Fisher SA.:  TRA2β controls Mypt1 exon 24 splicing in the developmental maturation of mouse mesenteric artery smooth muscle. Am J Physiol Cell Physiol 308(4):C289-96, 2015.  PMCID: PMC4329427
  8. Reho JJ, Zheng X, Benjamin JE, Fisher SA.: Neural programming of mesenteric and renal arteries. Am J Physiol Heart Circ Physiol 307(4): H563-573, 2014. PMID: 24929853
  9. Reho JJ, Zheng, X, Fisher SA.: Smooth muscle contractile diversity in the control of regional circulations. Am J Physiol Heart Circ Physiol 306(2): H163-172, 2014. PMID: 24186099
  10. Ditto AJ*, Reho JJ*, Shah KN, Smolen JA, Holda JA, Ramirez RJ, Yun YH.: In vivo non-viral gene delivery with L-tyrosine polyphosphate nanoparticles. Mol Pharm 10(5): 1836-1844, 2013. *Co-first authors PMID: 23510151
  11. Toot JD, Reho JJ, Ramirez RJ, Novak J, Ely DL.: Alterations in vasomotor systems and mechanics in resistance-sized mesenteric arteries from SHR and WKY male rats following in vivo testosterone manipulation. Biol Sex Differ 3(1): 1-13, 2012. PMID: 22214247
  12. Reho JJ, Toot JD, Peck J, Novak J, Yun YH, Ramirez RJ.: Increased myogenic reactivity of uterine arteries from pregnant rats with reduced uterine perfusion pressure. Pregnancy Hypertens 2(2): 106-114, 2012. PMID: 22679605
  13. Toot JD, Reho JJ, Novak J, Dunphy G, Ely DL, Ramirez RJ.: Testosterone increases myogenic reactivity of second-order mesenteric arteries in both defective and normal androgen receptor adult male rats. Gend Med 8(1): 40-52, 2011. PMID: 21497771
  14. Toot JD, Reho JJ, Novak J, Dunphy G, Ely DL, Ramirez RJ.: Colony social stress differentially alters blood pressure and resistance-sized mesenteric artery reactivity in SHR/y and WKY male rats. Stress 14(1): 33-41, 2011. PMID: 2066665
  15. Reho JJ, Peck J, Novak J, Ramirez RJ.: Hypertension induced by episodic reductions in uteroplacental blood flow in the gravid rat. Hypertens Pregnancy 30(2): 208-220, 2011. PMID: 20846047