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Charles Warwick

Address: 2-440 BSB
Phone: 353-3887
Email: charles-warwick@uiowa.edu

Mentor: Yuriy M. Usachev, PhD

PhD Institution: University of Iowa, 2017

Research Description

The role of the complement system, specifically C3a and C5a, in mediating chronic pain states using calcium imaging to examine the sensitization of nociceptors through complement activation.

Awards

  • Diabetes Research Training Program, 2017-present
  • PhRMA Foundation Predoctoral Fellowship, 2016-2017
  • NIH Fellowship appointment of Interdisciplinary Training in Pain Research (NIH T32 NS045549), University of Iowa, 2015-2016
  • Fellowship appointment of NIH Training Grant in Pharmacological Sciences (NIH T32 GM067795), University of Iowa, 2014-2015
  • Institutional fellowship support of Training Grant in Pharmacological Sciences (NIH T32 GM067795), University of Iowa, 2013-2014
  • Graduate Student Senate Travel Award, 2013-2016
  • Executive Council of Graduate & Professional Students Travel Award, 2013

Publications

  1. Shutov LP*, Warwick CA*, Shi X, Gnanasekaran A, Shepherd AJ, Mohapatra DP, Woodruff TM, Clark JD, Usachev YM.:  The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1. J Neurosci 36(18):5055-70, 2016.  PMCID: PMC4854968  *authors contributed equally to this work.  This article was selected as “Paper of the week” by Pain Research Forum (http://www.painresearchforum.org/).

Books / Chapters

  1. Warwick, CA and Usachev, YM "Culture, Transfection and Immunocytochemical Analysis of Primary Macrophages." Signal Transduction Immunohistochemistry: Methods and Protocols. 2nd ed. New York, NY: Humana, 2017. 161-173. Print.  PMID: 28185189