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Zhihong Lin, PhD

Address: 2-440 BSB
Phone: (319) 353-3887
Email: zhihong-lin@uiowa.edu

Mentor: Yuriy M. Usachev, PhD

PhD Institution: University of Regensburg, Germany, 2004

Research Description

The role of mitochondrial restructuring and Ca2+ transport in neuroprotection from excitotoxicity and hyperglycemia

Publications

  1. Hamilton J, Brustovetsky T, Rysted JE, Lin Z, Usachev YM, Brustovetsky N.:  Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria. J Biol Chem 293(40)15652-63, 2018. PMCID: PMC6177608
  2. Kim MS, Shutov LP, Gnanasekaran A, Lin Z, Rysted JE, Ulrich JD, Usachev YM.:  Nerve growth factor (NGF) regulates activity of nuclear factor of activated T-cells (NFAT) in neurons via the phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3β (GSK3β). J Biol Chem 289(45):31349-60, 2014.  PMCID: PMC4223335
  3. Wu J, Prole DL, Shen Y, Lin Z, Gnanasekaran A, Liu Y, Chen L, Zhou H, Chen SR, Usachev YM, Taylor CW, Campbell RE.:  Red fluorescent genetically encoded Ca2+ indicators for use in mitochondria and endoplasmic reticulum. Biochem J 464(1):13-22, 2014.  PMCID: PMC4214425
  4. Lin Z, Jin S, Duan X, Wang T, Martini S, Hulamm P, Cha B, Hubbard A, Donowitz M, and Guggino SE.:  Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger3 (NHE3). J Biol Chem. 286(26):22833-45, 2011.  PMCID: PMC3123051
  5. Lin Z, Wu M, Wolfbeis OS, Schaeferling M.:  A Novel method for time-resolved fluorimetric determination and imaging of the activity of peroxidase, and Its application to an enzyme-linked immunosorbent assay. Chemistry 12(10):2730-2738, 2006.
  6. Lin Z, Wu M, Wolfbeis OS.:  Time-resolved fluorescent chirality sensing and imaging of malate in aqueous solution. Chirality 17(8):464-469, 2005.
  7. Lin Z, Wu M, Schaeferling M, Wolfbeis OS.:  Fluorescent imaging of citrate and other intermediates in the citric acid cycle. Angewandte Chemie, International Edition 43(13):1735-1738, 2004.
  8. Wolfbeis OS, Duerkop A, Wu M, Lin Z.:  A Europium-ion-based luminescent sensing probe for hydrogen peroxide. Angewandte Chemie, International Edition 41(23):4495-4498, 2002.