Address: 2-505 BSB
Phone: (319) 335-8331
Email: kahlers@healthcare.uiowa.edu
Mentor: Rory Fisher, PhD
PhD Institution: University of Iowa, 2014
Research Description
Physiological and pathophysiological roles of a novel brain-specific isoform of Regulator of G protein signaling 6 (RGS6)
Awards
- Pharmacological and Pharmaceutical Sciences Research Retreat Poster Award, 2018
- Ranbir K. Bhatnagar Scholar Award, Department of Pharmacology, University of Iowa, 2018
- Ranbir K. Bhatnagar Scholar Award, Department of Pharmacology, University of Iowa, 2017
- ASBMB Postdoctoral Travel Award, 2016
Publications
- Chakravarti B, Yang J*, Ahlers-Dannen KE*, Luo Z, Flaherty HA, Meyerholz DK, Anderson ME, Fisher RA.: Essentiality of RGS6 and oxidized CaMKII in Notch signaling and cardiovascular development. J. Am. J Am Heart Assoc. 6(11), 2017. *Denotes co-second authors. PMCID: PMC5721783
- Yang J, Platt LT, Maity B, Ahlers KE, Luo Z, Lin Z, Chakravarti B, Ibeawuchi SR, Askeland RW, Bondaruk J, Czerniak BA, Fisher RA.: RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation. Oncotarget 7(43):69159-69172, 2016. PMCID: PMC5342467
- Ahlers KE, Chakravarti B, Fisher RA.: RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer. AAPS J 18(3):560-72, 2016. PMCID: PMC5256616
- Ahlers KE, Karacay B, Fuller L, Bonthius DJ, Dailey ME.: Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration. Glia 63(10):1694-713, 2015. PMCID: PMC4534325
- Eyo U, Miner S, Ahlers K, Wu LJ, Dailey ME.: P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation. Neuropharmacology 73:311-319, 2013. PMCID: PMC3786777