Javier Gomez, PhD

Address: 2-340 BSB
Phone: (319) 335-8926
Email: javier-gomez@uiowa.edu

Mentor: Curt D. Sigmund, PhD

PhD Institution: University of Iowa, 2016

Research Description

Role of ER and Oxidative stresses in the Brain Renin-Angiotnesin System

Publications

  1. Shinohara K, Nakagawa P, Gomez J, Morgan DA, Littlejohn NK, Folchert MD, Weidemann BJ, Liu X, Walsh SA, Ponto LL, Rahmouni K, Grobe JL, Sigmund CD.: Selective Deletion of Renin-b in the Brain Alters Drinking and Metabolism. Hypertension. 70(5):990-997, 2017.  PMCID: PMC5679092
  2. Diedrichs DR, Gomez JA, Huang CS, Rutkowski DT, Curtu R: A data-entrained computational model for testing the regulatory logic of the vertebrae unfolded protein response. Mol Biol Cell. 29(12):1502-1517, 2018. PMCID: PMC6014097
  3. Gomez JA, Rutkowski DT.:  Experimental Reconstitution of Chronic ER Stress in the Liver Reveals Feedback Suppression of BiP mRNA Expression. eLife. 5:e20390, 2016.  PMCID: PMC5179193
  4. Mao HZ, Ehrhardt N, Bedoya C, Gomez JA, DeZwaan-McCabe D, Mungrue I.N, Kaufman RJ, Rutkowski DT, Péterfy M.:  Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling. J Biol Chem. 289(35):24417-27, 2014.  PMCID: PMC4148868
  5. Gomez JA, Tyra HM, McCabe DD, Olivier AK, Rutkowski DT.:  Synthetic embryonic lethality upon deletion of the ER cochaperone p58IPK and the ER stress sensor ATF6α. Biochem. Biophys. Res. Comm. 443(1):115-119, 2014.  PMCID: PMC3901050