Every year, the University of Iowa Vaccine Research Unit conducts clinical trials on traditional flu vaccines with added adjuvants (agents that enhance the body’s immune system response). The unit also studies vaccines related to emerging public health issues and tests vaccines that could potentially be safer than the vaccines already being used. The University of Iowa site has been involved with National Institutes of Health studies testing new vaccines for H1N1, Avian H5N1, Smallpox, Yellow Fever, H5N8, Tuberculosis, and many more.