Publication Highlights
Gammaherpesvirus Infection Triggers the Formation of tRNA Fragments from Premature tRNAs
π Published: May 30, 2025
π ASM Journals
π©βπ¬ Lead Author: Jessica M. Tucker, PhD
π Read the full article β
π Research Summary
This study uncovers how gammaherpesvirus infection leads to the generation of tRNA fragments from premature tRNAs, shedding light on a previously underexplored aspect of host-virus interactions. The findings suggest that viral infection disrupts tRNA maturation, resulting in the accumulation of tRNA-derived fragments (tRFs) with potential regulatory roles.
π₯ Authors
Aidan C. Manning, Mahmoud M. Bashir, Kyle Rapchak, Calyssa J. Huff, Ariana R. Jimenez, Sheila Gonzalez, Courtney L. Woodruff, Heather E. Upton, Kathleen Collins, Todd M. Lowe, Jessica M. Tucker
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Welcome to the Department
Welcoming Dr. Alex Kleinpeter to the Department
Weβre happy to share that Dr. Alex Kleinpeter joined the Department of Microbiology and Immunology on May 30th. Please take a moment to give him a warm welcome!
Welcoming Dr. Amanda Dudek to the Department
We are excited to announce that Dr. Amanda Dudek will be joining the Department of Microbiology and Immunology on April 30th. We encourage everyone to extend a warm welcome to her upon her arrival.

Alex Kleinpeter, PhD
Assistant Professor of Microbiology and Immunology
