Publication Highlights

Gammaherpesvirus Infection Triggers the Formation of tRNA Fragments from Premature tRNAs

πŸ“… Published: May 30, 2025

πŸ“š ASM Journals

πŸ‘©β€πŸ”¬ Lead Author: Jessica M. Tucker, PhD

πŸ”— Read the full article β†’

πŸ” Research Summary

This study uncovers how gammaherpesvirus infection leads to the generation of tRNA fragments from premature tRNAs, shedding light on a previously underexplored aspect of host-virus interactions. The findings suggest that viral infection disrupts tRNA maturation, resulting in the accumulation of tRNA-derived fragments (tRFs) with potential regulatory roles.

πŸ‘₯ Authors

Aidan C. Manning, Mahmoud M. Bashir, Kyle Rapchak, Calyssa J. Huff, Ariana R. Jimenez, Sheila Gonzalez, Courtney L. Woodruff, Heather E. Upton, Kathleen Collins, Todd M. Lowe, Jessica M. Tucker

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Alex Kleinpeter, PhD

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Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion!This is open to ALL β€” students, staff, postdocs, and faculty interested in promoting women in science.Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.

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