Contact Information

Office: 2853 JPP 
Phone: 319-356-3539 
Faculty Profile

Brief description of current research:

My research interests include exploring mitochondrial function in offspring of diabetes mothers with a particular emphasis on mitochondrial superoxide production.  Clinically, I have an interest in the co-morbidities associated with obesity in children.  Dr. Vanessa Curtis in the Division of Pediatric Endocrinology and I run a weekly Pediatric Cardiometabolic Clinic to care for these children.  We are beginning to systematically intervene in this cohort of patients while collecting parameters of clinical success of our interventions. 

3 most influential diabetes/obesity/metabolism publications:

• Agoudemos, M, Reinking, BE, Koppenhafer, SL, Segar, JL, Scholz, TD.  Programming of adult cardiovascular disease following exposure to late-gestation hyperglycemia.  Neonatology 100(2):198-205, 2011, PMID: 21455011.
• Zinkhan, EK, Fu, Q, Wang, Y, Yu, X, Callaway, C, Segar, JL, Scholz, TD, McKnight, R, Joss-Moore, L, Lane, RH.  Maternal hyperglycemia decreases histone trimethylation of lysine 36 of the IGF-1 gene. J Nutr Metab 2012:2012:930364, PMID 22548154.
• Katkhuda, R., Peterson, ES, Roghair, RD, Norris, AW, Scholz, TD, Segar, JL. Sex-specific programming of hypertension in offspring of late gestation diabetic rats.  Pediatr Res 72(4):352-361, 2012, PMID 22805998