Wang R, Lu Y, Gunasekar S, Zhang Y, Benson CJ, Chapleau MW, Sah R, Abboud FM. The volume regulated anion channel (LRRC8) in nodose neurons is sensitive to acidic pH. JCI Insight. 2017 Mar 9;2(5):e90632. doi: 10.1172/jci.insight.90632. PubMed PMID: 28289711; PubMed Central PMCID: PMC5333957.
Konstam MA, Abboud FM. Ejection Fraction: Misunderstood and Overrated (Changing the Paradigm in Categorizing Heart Failure). Circulation. 2017 Feb 21;135(8):717-719. doi: 10.1161/CIRCULATIONAHA.116.025795. PubMed PMID: 28223323; PubMed Central PMCID: PMC5325053.
Singh MV, Cicha MZ, Kumar S, Meyerholz DK, Irani K, Chapleau MW, Abboud FM. Abnormal CD161(+) immune cells and retinoic acid receptor-related orphan receptor γt-mediate enhanced IL-17F expression in the setting of genetic hypertension. J Allergy Clin Immunol. 2017 Jan 16. pii: S0091-6749(17)30029-5. doi: 10.1016/j.jaci.2016.11.039. [Epub ahead of print] PubMed PMID: 28093217.
Abboud FM, Singh MV. Autonomic regulation of the immune system in cardiovascular diseases. Adv Physiol Educ. 2017 Dec 1;41(4):578-593. doi: 10.1152/advan.00061.2017. PubMed PMID: 29138216.
E. Dale Abel, MD, PhD:
Fidler TP, Middleton E, Rowley JW, Boudreau LH, Campbell RA, Souvenir R, Funari T, Tessandier N, Boilard E, Weyrich AS, Abel ED. Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation. Arterioscler Thromb Vasc Biol. 2017 Jun 29. pii: ATVBAHA.117.309184. doi: 10.1161/ATVBAHA.117.309184. [Epub ahead of print] PubMed PMID: 28663252.
Pereira RO, Tadinada SM, Zasadny FM, Oliveira KJ, Pires KMP, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017 Jun 12. pii: e201696179. doi: 10.15252/embj.201696179. [Epub ahead of print] PubMed PMID: 28607005.
Park SJ, Gavrilova O, Brown AL, Soto JE, Bremner S, Kim J, Xu X, Yang S, Um JH, Koch LG, Britton SL, Lieber RL, Philp A, Baar K, Kohama SG, Abel ED, Kim MK, Chung JH. DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging. Cell Metab. 2017 May 2;25(5):1135-1146.e7. doi: 10.1016/j.cmet.2017.04.008. PubMed PMID: 28467930; PubMed Central PMCID: PMC5485859.
Rines AK, Chang HC, Wu R, Sato T, Khechaduri A, Kouzu H, Shapiro J, Shang M, Burke MA, Jiang X, Chen C, Rawlings TA, Lopaschuk GD, Schumacker PT, Abel ED, Ardehali H. Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling. Nat Commun. 2017 Jan 24;8:14095. doi: 10.1038/ncomms14095. PubMed PMID: 28117339; PubMed Central PMCID: PMC5286102.
Wang Q, Liu Y, Fu Q, Xu B, Zhang Y, Kim S, Tan R, Barbagallo F, West T, Anderson E, Wei W, Abel ED, Xiang YK. Inhibiting Insulin-Mediated β2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction. Circulation. 2017 Jan 3;135(1):73-88. doi: 10.1161/CIRCULATIONAHA.116.022281. Epub 2016 Nov 4. PubMed PMID: 27815373; PubMed Central PMCID: PMC5302024.
Fidler TP, Campbell RA, Funari T, Dunne N, Balderas Angeles E, Middleton EA, Chaudhuri D, Weyrch AS, Abel ED. Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function. Cell Rep. 2017 Jul 25;20(4):881-894. doi: 10.1016/j.celrep.2017.06.083. PubMed PMID: 28746873.
McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Abel ED, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, Chatham JC, Young ME. Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart. J Mol Cell Cardiol. 2017 Jul 20;110:80-95. doi: 10.1016/j.yjmcc.2017.07.005. [Epub ahead of print] PubMed PMID: 28736261.
Fidler TP, Rowley JW, Araujo C, Boudreau LH, Marti A, Souvenir R, Dale K, Boilard E, Weyrich AS, Abel ED. Superoxide Dismutase 2 is dispensable for platelet function. Thromb Haemost. 2017 Aug 3;117(9). doi: 10.1160/TH17-03-0174. [Epub ahead of print] PubMed PMID: 28771279.
Wende AR, Kim J, Holland W, Wayment BE, O'Neill BT, Tuinei J, Brahma MK, Pepin ME, McCrory MA, Luptak I, Halade GV, Litwin SE, Abel ED. Glucose transporter 4 (GLUT4) deficient hearts develop maladaptive hypertrophy in response to physiologic or pathologic stresses. Am J Physiol Heart Circ Physiol. 2017 Aug 19:ajpheart.00101.2017. doi: 10.1152/ajpheart.00101.2017. [Epub ahead of print] PubMed PMID: 28822962.
Fidler TP, Campbell RA, Funari T, Dunne N, Balderas Angeles E, Middleton EA, Chaudhuri D, Weyrch AS, Abel ED. Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function. Cell Rep. 2017 Aug 29;20(9):2277. doi: 10.1016/j.celrep.2017.08.055. PubMed PMID: 28854375
Steinhorn B, Sartoretto JL, Sorrentino A, Romero N, Kalwa H, Abel ED, Michel T. Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4. Free Radic Biol Med. 2017 Sep 14;113:16-25. doi: 10.1016/j.freeradbiomed.2017.09.006. [Epub ahead of print] PubMed PMID: 28917508.
Pires KM, Buffolo M, Schaaf C, David Symons J, Cox J, Abel ED, Selzman CH, Boudina S. Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice. J Mol Cell Cardiol. 2017 Oct 5;113:39-50. doi: 10.1016/j.yjmcc.2017.10.001. [Epub ahead of print] PubMed PMID: 28987875.
Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Black CL, Pereira RO, Lira VA, Spitzer K, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED. Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induces Post-Translational Modifications of AKAP121, DRP1 and OPA1 That Promote Mitochondrial Fission. Circ Res. 2017 Nov 1. pii: CIRCRESAHA.117.311307. doi: 10.1161/CIRCRESAHA.117.311307. [Epub ahead of print] PubMed PMID: 29092894.
Nabeebaccus AA, Zoccarato A, Hafstad AD, Santos CX, Aasum E, Brewer AC, Zhang M, Beretta M, Yin X, West JA, Schröder K, Griffin JL, Eykyn TR, Abel ED, Mayr M, Shah AM. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation. JCI Insight. 2017 Dec 21;2(24). pii: 96184. doi: 10.1172/jci.insight.96184. [Epub ahead of print] PubMed PMID: 29263294.
Michael Abramoff, MD, PhD:
Lynch SK, Abràmoff MD. Diabetic retinopathy is a neurodegenerative disorder. Vision Res. 2017 Apr 27. pii: S0042-6989(17)30048-2. doi: 10.1016/j.visres.2017.03.003. [Epub ahead of print] PubMed PMID: 28408138.
Xu X, Ding W, Abràmoff MD, Cao R. An improved arteriovenous classification method for the early diagnostics of various diseases in retinal image. Comput Methods Programs Biomed. 2017 Apr;141:3-9. doi: 10.1016/j.cmpb.2017.01.007. Epub 2017 Jan 17. PubMed PMID: 28241966.
Klein BE, Johnson CA, Meuer SM, Lee K, Wahle A, Lee KE, Kulkarni A, Sonka M, Abràmoff MD, Klein R. Nerve Fiber Layer Thickness and Characteristics Associated with Glaucoma in Community Living Older Adults: Prelude to a Screening Trial? Ophthalmic Epidemiol. 2017 Apr;24(2):104-110. doi: 10.1080/09286586.2016.1258082. Epub 2016 Dec 29. PubMed PMID: 28032805.
Miri MS, Robles VA, Abràmoff MD, Kwon YH, Garvin MK. Incorporation of gradient vector flow field in a multimodal graph-theoretic approach for segmenting the internal limiting membrane from glaucomatous optic nerve head-centered SD-OCT volumes. Comput Med Imaging Graph. 2017 Jan;55:87-94. doi: 10.1016/j.compmedimag.2016.06.007. Epub 2016 Jul 25. PubMed PMID: 27507325; PubMed Central PMCID: PMC5219948.
Klein BE, Johnson CA, Meuer SM, Lee K, Wahle A, Lee KE, Kulkarni A, Sonka M, Abràmoff MD, Klein R. Nerve Fiber Layer Thickness and Characteristics Associated with Glaucoma in Community Living Older Adults: Prelude to a Screening Trial? Ophthalmic Epidemiol. 2017 Apr;24(2):104-110. doi: 10.1080/09286586.2016.1258082. Epub 2016 Dec 29. PubMed PMID: 28032805.
Guo Z, Kwon YH, Lee K, Wang K, Wahle A, Alward WLM, Fingert JH, Bettis DI, Johnson CA, Garvin MK, Sonka M, Abràmoff MD. Optical Coherence Tomography Analysis Based Prediction of Humphrey 24-2 Visual Field Thresholds in Patients With Glaucoma. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3975-3985. doi: 10.1167/iovs.17-21832. PubMed PMID: 28796875.
Lee SY, Cheng JL, Gehrs KM, Folk JC, Sohn EH, Russell SR, Guo Z, Abràmoff MD, Han IC. Choroidal Features of Acute Macular Neuroretinopathy via Optical Coherence Tomography Angiography and Correlation With Serial Multimodal Imaging. JAMA Ophthalmol. 2017 Sep 28. doi: 10.1001/jamaophthalmol.2017.3790. [Epub ahead of print] PubMed PMID: 28973538.
Zhang Y, Chioreso C, Schweizer ML, Abràmoff MD. Effects of Aflibercept for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Observational Comparative Studies. Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5616-5627. doi: 10.1167/iovs.17-22471. PubMed PMID: 29094167; PubMed Central PMCID: PMC5667400.
van der Heijden AA, Abramoff MD, Verbraak F, van Hecke MV, Liem A, Nijpels G. Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System. Acta Ophthalmol. 2017 Nov 27. doi: 10.1111/aos.13613. [Epub ahead of print] PubMed PMID: 29178249.
Christopher Adams, MD, PhD:
Nikonorova IA, Al-Baghdadi RJT, Mirek ET, Wang Y, Goudie MP, Wetstein BB, Dixon JL, Hine C, Mitchell JR, Adams CM, Wek RC, Anthony TG. Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice. J Biol Chem. 2017 Apr 21;292(16):6786-6798. doi: 10.1074/jbc.M116.768408. Epub 2017 Feb 27. PubMed PMID: 28242759; PubMed Central PMCID: PMC5399125.
Adams CM, Ebert SM, Dyle MC. Role of ATF4 in skeletal muscle atrophy. Curr Opin Clin Nutr Metab Care. 2017 May;20(3):164-168. doi: 10.1097/MCO.0000000000000362. PubMed PMID: 28376050.
Ethan Anderson, PhD:
Nelson MM, Baba SP, Anderson EJ. Biogenic Aldehydes as Therapeutic Targets for Cardiovascular Disease. Curr Opin Pharmacol. 2017 Apr;33:56-63. doi: 10.1016/j.coph.2017.04.004. Epub 2017 May 18. Review.
Efird JT, Kiser AC, Crane PB, Landrine H, Kindell LC, Nelson MA, Jindal C, Sarpong DF, Griffin WF, Ferguson TB, Chitwood WR, Davies SW, Kypson AP, Gudimella P, Anderson EJ. Perioperative Inotrope Therapy and Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery: Evidence of a Racial Disparity. Pharmacotherapy. 2017 Mar;37(3):297-304. doi: 10.1002/phar.1894. Epub 2017 Feb 3. PubMed PMID: 28052357. PubMed PMID: 28528297.
Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. J Biol Chem. 2017 Nov 21. pii: jbc.M117.812834. doi: 10.1074/jbc.M117.812834. [Epub ahead of print] PubMed PMID: 29162722.
Michael Anderson, MD, PhD:
Meyer KJ, Anderson MG. Genetic modifiers as relevant biological variables of eye disorders. Hum Mol Genet. 2017 May 8. doi: 10.1093/hmg/ddx180. [Epub ahead of print] PubMed PMID: 28482014.
Fingert JH, Miller K, Hedberg-Buenz A, Roos BR, Lewis CJ, Mullins RF, Anderson MG. Transgenic TBK1 mice have features of normal tension glaucoma. Hum Mol Genet. 2017 Jan 1;26(1):124-132. doi: 10.1093/hmg/ddw372. PubMed PMID: 28025332.
Wang C, Brancusi F, Valivullah ZM, Anderson MG, Cunningham D, Hedberg-Buenz A, Power B, Simeonov D, Gahl WA, Zein WM, Adams DR, Brooks B. A novel iris transillumination grading scale allowing flexible assessment with quantitative image analysis and visual matching. Ophthalmic Genet. 2017 Jul 25:1-5. doi: 10.1080/13816810.2017.1342134. [Epub ahead of print] PubMed PMID: 28742462.
James Ankrum, PhD:
Burand AJ, Gramlich OW, Brown AJ, Ankrum JA. Function of Cryopreserved Mesenchymal Stromal Cells With and Without Interferon-γ Prelicensing is Context Dependent. Stem Cells. 2017 May;35(5):1437-1439. doi: 10.1002/stem.2528. Epub 2016 Nov 10. PubMed PMID: 27758056; PubMed Central PMCID: PMC5397371.
Wei Bao, MD, PhD:
Osorio-Yáñez C, Gelaye B, Qiu C, Bao W, Cardenas A, Enquobahrie DA, Williams MA. Maternal intake of fried foods and risk of gestational diabetes mellitus. Ann Epidemiol. 2017 Jun;27(6):384-390.e1. doi: 10.1016/j.annepidem.2017.05.006. Epub 2017 May 12. PubMed PMID: 28641758.
Bowers KA, Olsen SF, Bao W, Halldorsson TI, Strøm M, Zhang C. Plasma Concentrations of Ferritin in Early Pregnancy Are Associated with Risk of Gestational Diabetes Mellitus in Women in the Danish National Birth Cohort. J Nutr. 2016 Sep;146(9):1756-61. doi: 10.3945/jn.115.227793. Epub 2016 Aug 10. PubMed PMID: 27511926; PubMed Central PMCID: PMC4997275.
Bao W, Dar S, Zhu Y, Wu J, Rawal S, Li S, Weir NL, Tsai MY, Zhang C (2017). Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study. Journal of Diabetes. In press.
Liu B, Lehmler H, Sun Y, Xu G, Liu Y, Zong G, Sun Q, Hu FB, Wallace RB, Bao W (2017). Bisphenol A substitutes and obesity in US adults: analysis of a population-based, crosssectional study. The Lancet Planetary Health, 1(3):e114-e122.
Shostrom DC, Sun Y, Oleson JJ, Snetselaar LG, Bao W (2017). History of Gestational Diabetes Mellitus in Relation to Cardiovascular Disease and Cardiovascular Risk Factors in US Women. Frontiers in Endocrinology, 8:144.
Rawal S, Hinkle SN, Bao W, Zhu Y, Grewal J, Albert PS, Weir NL, Tsai MY, Zhang C (2017). A longitudinal study of iron status during pregnancy and the risk of gestational diabetes: findings from a prospective, multiracial cohort. Diabetologia, 60(2):249-257.
Chen S, Jin X, Shan Z, Li S, Yin J, Sun T, Luo C, Yang W, Yao P, Yu K, Zhang Y, Cheng Q, Cheng J, Bao W, Liu L. (2017). Inverse Association of Plasma Chromium Levels with Newly Diagnosed Type 2 Diabetes: A Case-Control Study. Nutrients, 9(3):294.
Zheng X, Huang B, Luo S, Yang D, Bao W, Li J, Yao B, Weng J, Yan J (2017). A New Model to Estimate Insulin Resistance via Clinical Parameters in Adults with Type 1 Diabetes. Diabetes/Metabolism Research and Reviews, 33(4):e2880.
Yin J, Jin X, Shan Z, Li S, Huang H, Li P, Peng X, Peng Z, Yu K, Bao W, Yang W, Chen X, Liu L. Relationship of Sleep Duration With All-Cause Mortality and Cardiovascular Events: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. J Am Heart Assoc. 2017 Sep 9;6(9). pii: e005947. doi: 10.1161/JAHA.117.005947. Review. PubMed PMID: 28889101.
Chen S, Jin X, Liu J, Sun T, Xie M, Bao W, Yu X, Yang X, Zhang Y, Zhang H, Shan Z, Liu L. Association of Plasma Magnesium with Prediabetes and Type 2 Diabetes Mellitus in Adults. Sci Rep. 2017 Oct 6;7(1):12763. doi: 10.1038/s41598-017-13050-7. PubMed PMID: 28986547.
Bao W, Song Y, Bertrand KA, Tobias DK, Olsen SF, Chavarro JE, Mills JL, Hu FB, Zhang C. Pre-pregnancy habitual intake of vitamin D from diet and supplements in relation to risk of gestational diabetes mellitus: a prospective cohort study. J Diabetes. 2017 Oct 4. doi: 10.1111/1753-0407.12611. [Epub ahead of print] PubMed PMID: 28976079.
Zhang B, Zhao Q, Guo W, Bao W, Wang X. Association of whole grain intake with all-cause, cardiovascular, and cancer mortality: a systematic review and dose-response meta-analysis from prospective cohort studies. Eur J Clin Nutr. 2017 Nov 1. doi: 10.1038/ejcn.2017.149. [Epub ahead of print] Review. PubMed PMID: 29091078.
Gail Bishop, PhD:
Wallis AM, Wallace EC, Hostager BS, Yi Z, Houtman JCD, Bishop GA. TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22. Sci Rep. 2017 May 18;7(1):2081. doi: 10.1038/s41598-017-02280-4. PubMed PMID: 28522807; PubMed Central PMCID: PMC5437045.
Ryan Boudreau, PhD:
Liu W, Deng J, Ding W, Wang G, Shen Y, Zheng J, Zhang X, Luo Y, Lv C, Wang Y, Chen L, Yan D, Boudreau RL, Song LS, Liu J. Decreased KCNE2 ExpressionParticipates in the Development of Cardiac Hypertrophy by Regulation of Calcineurin-NFAT (Nuclear Factor of Activated T Cells) and Mitogen-Activated Protein Kinase Pathways. Circ Heart Fail. 2017 Jun;10(6). pii: e003960. doi: 10.1161/CIRCHEARTFAILURE.117.003960. PubMed PMID: 28611128.
Boudreau RL. The Next Best Thing in Cardiovascular Research: Highlights From the Basic Cardiovascular Sciences Scientific Sessions. J Am Heart Assoc. 2017 Sep 20;6(9). pii: e007245. doi: 10.1161/JAHA.117.007245. PubMed PMID: 28931530.
Charles Brenner, PhD:
Wilsbacher JL, Cheng M, Cheng D, Trammell SAJ, Shi Y, Guo J, Koeniger SL, Kovar PJ, He Y, Selvaraju S, Heyman HR, Sorensen BK, Clark RF, Hansen TM, Longenecker KL, Raich D, Korepanova AV, Cepa S, Towne DL, Abraham VC, Tang H, Richardson PL, McLoughlin SM, Badagnani I, Curtin ML, Michaelides MR, Maag D, Buchanan FG, Chiang GG, Gao W, Rosenberg SH, Brenner C, Tse C. Discovery and Characterization of Novel Non-substrate and Substrate NAMPT Inhibitors. Mol Cancer Ther. 2017 May 3. pii: molcanther.0819.2016. doi: 10.1158/1535-7163.MCT-16-0819. [Epub ahead of print] PubMed PMID: 28468779.
Hamity MV, White SR, Walder RY, Schmidt MS, Brenner C, Hammond DL. Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel induced peripheral neuropathy in female rats. Pain. 2017 May;158(5):962-972. doi: 10.1097/j.pain.0000000000000862. PubMed PMID: 28346814.
Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug. PubMed PMID: 28752046; PubMed Central PMCID: PMC5518663.
Sato S, Solanas G, Peixoto FO, Bee L, Symeonidi A, Schmidt MS, Brenner C, Masri S, Benitah SA, Sassone-Corsi P. Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging. Cell. 2017 Aug 10;170(4):664-677.e11. doi: 10.1016/j.cell.2017.07.042. PubMed PMID: 28802039.
Vaur P, Brugg B, Mericskay M, Li Z, Schmidt MS, Vivien D, Orset C, Jacotot E, Brenner C, Duplus E. Nicotinamide riboside, a form of vitamin B(3), protects against excitotoxicity-induced axonal degeneration. FASEB J. 2017 Aug 21. pii: fj.201700221RR. doi: 10.1096/fj.201700221RR. [Epub ahead of print] PubMed PMID: 28842432.
Diguet N, Trammell SAJ, Tannous C, Deloux R, Piquereau J, Mougenot N, Gouge A, Gressette M, Manoury B, Blanc J, Breton M, Decaux JF, Lavery G, Baczkó I, Zoll J, Garnier A, Li Z, Brenner C, Mericskay M. Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy. Circulation. 2017 Dec 7. pii: CIRCULATIONAHA.116.026099. doi: 10.1161/CIRCULATIONAHA.116.026099. [Epub ahead of print] PubMed PMID: 29217642.
Fangmann D, Theismann EM, Türk K, Schulte DM, Relling I, Hartmann K, Keppler JK, Knipp JR, Rehman A, Heinsen FA, Franke A, Lenk L, Freitag-Wolf S, Appel E, Gorb S, Brenner C, Seegert D, Waetzig GH, Rosenstiel P, Schreiber S, Schwarz K, Laudes M. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans. Diabetes Care. 2017 Dec 6. pii: dc171967. doi: 10.2337/dc17-1967. [Epub ahead of print] PubMed PMID: 29212824.
Trudy Burns, PhD:
Janz KF, Boros P, Letuchy EM, Kwon S, Burns TL, Levy SM. Physical Activity, Not Sedentary Time, Predicts DXA-Measured Adiposity Age 5-19 Years. Med Sci Sports Exerc. 2017 Jun 2. doi: 10.1249/MSS.0000000000001336. [Epub ahead of print] PubMed PMID: 28574873.
Kwon S, Janz KF, Letuchy EM, Burns TL, Levy SM. Association between body mass index percentile trajectories in infancy and adiposity in childhood and early adulthood. Obesity (Silver Spring). 2017 Jan;25(1):166-171. doi: 10.1002/oby.21673. Epub 2016 Nov 2. PubMed PMID: 27804242; PubMed Central PMCID: PMC5182145.
Calarge CA, Mills JA, Janz KF, Burns TL, Coryell WH, Zemel BS. Body Composition in Adolescents During Treatment With Selective Serotonin Reuptake Inhibitors. Pediatrics. 2017 Jul;140(1). pii: e20163943. doi: 10.1542/peds.2016-3943. Epub 2017 Jun 16. PubMed PMID: 28759400.
Calarge CA, Mills JA, Janz KF, Burns TL, Schlechte JA, Coryell WH, Zemel BS. The Effect of Depression, Generalized Anxiety, and Selective Serotonin Reuptake Inhibitors on Change in Bone Metabolism in Adolescents and Emerging Adults. J Bone Miner Res. 2017 Aug 16. doi: 10.1002/jbmr.3238. [Epub ahead of print] PubMed PMID: 28815738.
Janz KF, Boros P, Letuchy EM, Kwon S, Burns TL, Levy SM. Physical Activity, Not Sedentary Time, Predicts Dual-Energy X-ray Absorptiometry-measured Adiposity Age 5 to 19 Years. Med Sci Sports Exerc. 2017 Oct;49(10):2071-2077. doi: 10.1249/MSS.0000000000001336. PubMed PMID: 28915225.
Koskinen J, Juonala M, Dwyer T, Venn A, Thomson R, Bazzano L, Berenson GS, Sabin MA, Burns TL, Viikari JSA, Woo JG, Urbina EM, Prineas R, Hutri-Kähönen N, Sinaiko A, Jacobs D, Steinberger J, Daniels S, Raitakari OT, Magnussen CG. Impact of Lipid Measurements in Youth in Addition to Conventional Clinic-Based Risk Factors on Predicting Preclinical Atherosclerosis in Adulthood: The International Childhood Cardiovascular Cohort (i3C) Consortium. Circulation. 2017 Nov 23. pii: CIRCULATIONAHA.117.029726. doi: 10.1161/CIRCULATIONAHA.117.029726. [Epub ahead of print] PubMed PMID: 29170152.
Lucas Carr, PhD:
Jao YL, Gardner SE, Carr LJ. Measuring Weight-Bearing Activities in Patients With Previous Diabetic Foot Ulcers. J Wound Ostomy Continence Nurs. 2017 Jan/Feb;44(1):34-40. doi: 10.1097/WON.0000000000000270. PubMed PMID: 27556347.
Carr LJ, Dunsinger S, Marcus BH. Long-term Surveillance of Physical Activity Habits of Latinas Enrolled in a 12-Month Physical Activity Intervention. J Phys Act Health. 2016 Jul;13(7):740-6. doi: 10.1123/jpah.2015-0482. Epub 2016 Feb 19. PubMed PMID: 26901839.
Jerome M, Janz KF, Baquero B, Carr LJ. Introducing sit-stand desks increases classroom standing time among university students. Prev Med Rep. 2017 Nov 9;8:232-237. doi: 10.1016/j.pmedr.2017.10.019. eCollection 2017 Dec. PubMed PMID: 29159019; PubMed Central PMCID: PMC5683670.
Darren Casey, PhD:
Harvey RE, Barnes JN, Hart EC, Nicholson WT, Joyner MJ, Casey DP. Influence of sympathetic nerve activity on aortic hemodynamics and pulse wave velocity in women. Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H340-H346. doi: 10.1152/ajpheart.00447.2016. Epub 2016 Dec 6. PubMed PMID: 27923789; PubMed Central PMCID: PMC5336574.
Kruse NT, Hughes WE, Ueda K, Casey DP. Vasoconstrictor responsiveness in contracting human muscle: influence of contraction frequency, contractile work, and metabolic rate. Eur J Appl Physiol. 2017 Jun 17. doi: 10.1007/s00421-017-3660-7. [Epub ahead of print] PubMed PMID: 28624852.
Hughes WE, Kruse NT, Casey DP. Sympathetic Nervous System Activation Reduces Contraction-Induced Rapid Vasodilation in the Leg of Humans Independent of Age. J Appl Physiol (1985). 2017 Apr 6:jap.00005.2017. doi: 10.1152/japplphysiol.00005.2017. [Epub ahead of print] PubMed PMID: 28385914.
Hughes WE, Casey DP. Aortic Wave Reflection During Orthostatic Challenges: Influence of Body Position and Venous Pooling. Am J Hypertens. 2017 Feb;30(2):166-172. doi: 10.1093/ajh/hpw138. Epub 2016 Nov 10. PubMed PMID: 28077421.
Iwamoto E, Bock JM, Casey DP. High-Intensity Exercise Enhances Conduit Artery Vascular Function in Older Adults. Med Sci Sports Exerc. 2017 Aug 16. doi: 10.1249/MSS.0000000000001405. [Epub ahead of print] PubMed PMID: 28817509.
Bock JM, Ueda K, Schneider AC 4th, Hughes WE, Limberg JK, Bryan NS, Casey DP. Inorganic nitrate supplementation attenuates peripheral chemoreflex sensitivity but does not improve cardiovagal baroreflex sensitivity in older adults. Am J Physiol Heart Circ Physiol. 2017 Sep 29:ajpheart.00389.2017. doi: 10.1152/ajpheart.00389.2017. [Epub ahead of print] PubMed PMID: 28971842.
Kruse NT, Hughes WE, Hanada S, Ueda K, Bock JM, Iwamoto E, Casey DP. Evidence of a greater functional sympatholysis in habitually aerobic trained postmenopausal women. J Appl Physiol (1985). 2017 Sep 28:jap.00411.2017. doi: 10.1152/japplphysiol.00411.2017. [Epub ahead of print] PubMed PMID: 28970201.
Kruse NT, Hughes WE, Benzo RM, Carr LJ, Casey DP. Workplace Strategies to Prevent Sitting-induced Endothelial Dysfunction. Med Sci Sports Exerc. 2017 Nov 7. doi: 10.1249/MSS.0000000000001484. [Epub ahead of print] PubMed PMID: 29117072.
Mark Chapleau, PhD:
Chapleau MW, Rotella DL, Reho JJ, Rahmouni K, Stauss HM. Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H276-85. doi: 10.1152/ajpheart.00043.2016. Epub 2016 May 20. PubMed PMID: 27208157; PubMed Central PMCID: PMC4967207.
Huxing Cui, PhD:
Cui H, López M, Rahmouni K. The cellular and molecular bases of leptin and ghrelin resistance in obesity. Nat Rev Endocrinol. 2017 Jun;13(6):338-351. doi: 10.1038/nrendo.2016.222. Epub 2017 Feb 24. Review. PubMed PMID: 28232667.
Lutter M, Bahl E, Hannah C, Hofammann D, Acevedo S, Cui H, McAdams CJ, Michaelson JJ. Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors. PLoS One. 2017 Aug 28;12(8):e0181556. doi: 10.1371/journal.pone.0181556. eCollection 2017. PubMed PMID: 28846695.
Sandra Daack-Hirsch, PhD, RN:
Seven M, Akyüz A, Eroglu K, Daack-Hirsch S, Skirton H. Women's knowledge and use of prenatal screening tests. J Clin Nurs. 2017 Jul;26(13-14):1869-1877. doi: 10.1111/jocn.13494. Epub 2017 Mar 20. PubMed PMID: 27487389.
Brandon Davies, PhD:
Cushing EM, Chi X, Sylvers KL, Shetty SK, Potthoff MJ, Davies BSJ. Angiopoietin-like 4 directs uptake of dietary fat away from adipose during fasting. Mol Metab. 2017 Jun 19;6(8):809-818. doi: 10.1016/j.molmet.2017.06.007. eCollection 2017 Aug. PubMed PMID: 28752045; PubMed Central PMCID: PMC5518724.
Chi X, Britt EC, Shows HW, Hjelmaas AJ, Shetty SK, Cushing EM, Li W, Dou A, Zhang R, Davies BSJ. ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase. Mol Metab. 2017 Oct;6(10):1137-1149. doi: 10.1016/j.molmet.2017.06.014. Epub 2017 Jun 29. PubMed PMID: 29031715.
Joseph Dillon, MD:
Strosberg JR, Halfdanarson TR, Bellizzi AM, Chan JA, Dillon JS, Heaney AP, Kunz PL, O'Dorisio TM, Salem R, Segelov E, Howe JR, Pommier RF, Brendtro K, Bashir MA, Singh S, Soulen MC, Tang L, Zacks JS, Yao JC, Bergsland EK. The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors. Pancreas. 2017 Jul;46(6):707-714. doi: 10.1097/MPA.0000000000000850. PubMed PMID: 28609356.
Menda Y, O'Dorisio TM, Howe JR, Schultz M, Dillon JS, Dick D, Watkins GL, Ginader T, Bushnell DL, Sunderland JJ, Zamba GKD, Graham M, O'Dorisio MS. Localization of Unknown Primary Site with (68)Ga-DOTATOC PET/CT in Patients with Metastatic Neuroendocrine Tumor. J Nucl Med. 2017 Jul;58(7):1054-1057. doi: 10.2967/jnumed.116.180984. Epub 2017 Feb 2. PubMed PMID: 28153957; PubMed Central PMCID: PMC5493006.
John Engelhardt, PhD:
Wang Z, Shen W, Cheng F, Deng X, Engelhardt JF, Yan Z, Qiu J. Parvovirus Expresses a Small Noncoding RNA That Plays an Essential Role in Virus Replication. J Virol. 2017 Mar 29;91(8). pii: e02375-16. doi: 10.1128/JVI.02375-16. Print 2017 Apr 15. PubMed PMID: 28122984; PubMed Central PMCID: PMC5375684.
Deng X, Xu P, Zou W, Shen W, Peng J, Liu K, Engelhardt JF, Yan Z, Qiu J. DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells. J Virol. 2016 Dec 16;91(1). pii: e01831-16. Print 2017 Jan 1. PubMed PMID: 27733644; PubMed Central PMCID: PMC5165215.
Pillay S, Zou W, Cheng F, Puschnik AS, Meyer NL, Ganaie SS, Deng X, Wosen JE, Davulcu O, Yan Z, Engelhardt JF, Brown KE, Chapman MS, Qiu J, Carette JE. AAV serotypes have distinctive interactions with domains of the cellular receptor AAVR. J Virol. 2017 Jul 5. pii: JVI.00391-17. doi: 10.1128/JVI.00391-17. [Epub ahead of print] PubMed PMID: 28679762.
Guggino W, Benson J, Seagrave J, Yan Z, Engelhardt JF, Gao G, Conlon TJ, Cebotaru L. A PRECLINICAL STUDY IN RHESUS MACAQUES FOR CYSTIC FIBROSIS TO ASSESS GENE TRANSFER AND TRANSDUCTION BY AAV1 AND AAV5 WITH A DUAL-LUCIFERASE REPORTER SYSTEM. Hum Gene Ther Clin Dev. 2017 Jul 20. doi: 10.1089/humc.2017.067. [Epub ahead of print] PubMed PMID: 28726496.
Hao Z, Zhu Y, Wang X, Rotti P, DiMarco C, Tyler S, Zhao X, Engelhardt JF, Hone JC, Lin Q. Real-Time Monitoring of Insulin Using a Graphene Field-Effect Transistor Aptameric Nanosensor. ACS Appl Mater Interfaces. 2017 Aug 3. doi: 10.1021/acsami.7b07684. [Epub ahead of print] PubMed PMID: 28770993.
Rosen BH, Chanson M, Gawenis LR, Liu J, Sofoluwe A, Zoso A, Engelhardt JF. Animal and model systems for studying cystic fibrosis. J Cyst Fibros. 2017 Sep 19. pii: S1569-1993(17)30880-9. doi: 10.1016/j.jcf.2017.09.001. [Epub ahead of print] PubMed PMID: 28939349.
Sun X, Yi Y, Xie W, Liang B, Winter MC, He N, Liu X, Luo M, Yang Y, Ode KL, Uc A, Norris AW, Engelhardt JF. CFTR Influences Beta Cell Function and Insulin Secretion Through Non-Cell Autonomous Exocrine-Derived Factors. Endocrinology. 2017 Oct 1;158(10):3325-3338. doi: 10.1210/en.2017-00187. PubMed PMID: 28977592.
Frank Faraci, PhD:
Dayal S, Baumbach GL, Arning E, Bottiglieri T, Faraci FM, Lentz SR. Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia. PLoS One. 2017 Apr 17;12(4):e0175732. doi: 10.1371/journal.pone.0175732. eCollection 2017. PubMed PMID: 28414812; PubMed Central PMCID: PMC5393600.
De Silva TM, Hu C, Kinzenbaw DA, Modrick ML, Sigmund CD, Faraci FM. Genetic Interference With Endothelial Peroxisome Proliferator-Activated Receptor-γ Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7. Hypertension. 2017 Jul 3. pii: HYPERTENSIONAHA.117.09358. doi: 10.1161/HYPERTENSIONAHA.117.09358. [Epub ahead of print] PubMed PMID: 28674038.
Hu X, De Silva TM, Chen J, Faraci FM. Cerebral Vascular Disease and Neurovascular Injury in Ischemic Stroke. Circ Res. 2017 Feb 3;120(3):449-471. doi: 10.1161/CIRCRESAHA.116.308427. Review. PubMed PMID: 28154097; PubMed Central PMCID: PMC5313039.
Baron-Menguy C, Domenga-Denier V, Ghezali L, Faraci FM, Joutel A. Increased Notch3 Activity Mediates Pathological Changes in Structure of Cerebral Arteries. Hypertension. 2017 Jan;69(1):60-70. Epub 2016 Nov 7. PubMed PMID: 27821617; PubMed Central PMCID: PMC5145742.
Li Y, Kinzenbaw DA, Modrick ML, Pewe LL, Faraci FM. Context-dependent effects of SOCS3 in angiotensin II-induced vascular dysfunction and hypertension in mice: mechanisms and role of bone marrow-derived cells. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H146-56. doi: 10.1152/ajpheart.00204.2016. Epub 2016 Apr 22. PubMed PMID: 27106041; PubMed Central PMCID: PMC4967211.
Faraci FM. Disease Highlights the Cellular Diversity of Neurovascular Units: Sign in Stranger. Circ Res. 2017 Jul 21;121(3):203-205. doi: 10.1161/CIRCRESAHA.117.311386. PubMed PMID: 28729449.
James Folk, MD:
Chin EK, Almeida DRP, Velez G, Xu K, Peraire M, Corbella M, Elshatory YM, Kwon YH, Gehrs KM, Boldt HC, Sohn EH, Russell SR, Folk JC, Mahajan VB. OCULAR HYPERTENSION AFTER INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT. Retina. 2017 Jul;37(7):1345-1351. doi: 10.1097/IAE.0000000000001364. PubMed PMID: 27806001; PubMed Central PMCID: PMC5411345.
Olsen TW, Pulido JS, Folk JC, Hyman L, Flaxel CJ, Adelman RA. Retinal and Ophthalmic Artery Occlusions Preferred Practice Pattern®. Ophthalmology. 2017 Feb;124(2):P120-P143. doi: 10.1016/j.ophtha.2016.09.024. Epub 2016 Oct 11. PubMed PMID: 27742458.
David Frisvold, PhD:
Frisvold DE, Jung Y. The impact of expanding Medicaid on health insurance coverage and labor market outcomes. Int J Health Econ Manag. 2017 Sep 22. doi: 10.1007/s10754-017-9226-8. [Epub ahead of print] PubMed PMID: 28940021.
Cawley J, Willage B, Frisvold D. Pass-Through of a Tax on Sugar-Sweetened Beverages at the Philadelphia International Airport. JAMA. 2017 Oct 25. doi: 10.1001/jama.2017.16903. [Epub ahead of print] PubMed PMID: 29071342.
Bernd Fritzsch, PhD:
Elliott KL, Kersigo J, Pan N, Jahan I, Fritzsch B. Spiral Ganglion Neuron Projection Development to the Hindbrain in Mice Lacking Peripheral and/or Central Target Differentiation. Front Neural Circuits. 2017 Apr 13;11:25. doi: 10.3389/fncir.2017.00025. eCollection 2017. PubMed PMID: 28450830; PubMed Central PMCID: PMC5389974.
Bohuslavova R, Dodd N, Macova I, Chumak T, Horak M, Syka J, Fritzsch B, Pavlinkova G. Pax2-Islet1 Transgenic Mice Are Hyperactive and Have Altered Cerebellar Foliation. Mol Neurobiol. 2017 Mar;54(2):1352-1368. doi: 10.1007/s12035-016-9716-6. Epub 2016 Feb 3. PubMed PMID: 26843111; PubMed Central PMCID: PMC5310572.
Fritzsch B, Elliott KL, Glover JC. Gaskell revisited: new insights into spinal autonomics necessitate a revised motor neuron nomenclature. Cell Tissue Res. 2017 Aug 31. doi: 10.1007/s00441-017-2676-y. [Epub ahead of print] Review. PubMed PMID: 28856468.
Song Z, Jadali A, Fritzsch B, Kwan KY. NEUROG1 Regulates CDK2 to Promote Proliferation in Otic Progenitors. Stem Cell Reports. 2017 Oct 11. pii: S2213-6711(17)30418-6. doi: 10.1016/j.stemcr.2017.09.011. [Epub ahead of print] PubMed PMID: 29033307.
Mark Greiner, MD:
Aldrich BT, Schlötzer-Schrehardt U, Skeie JM, Burckart KA, Schmidt GA, Reed CR, Zimmerman MB, Kruse FE, Greiner MA. Mitochondrial and Morphologic Alterations in Native Human Corneal Endothelial Cells Associated With Diabetes Mellitus. Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2130-2138. doi: 10.1167/iovs.16-21094. PubMed PMID: 28395029.
Liaboe CA, Aldrich BT, Carter PC, Skeie JM, Burckart KA, Schmidt GA, Reed CR, Zimmerman MB, Greiner MA. Assessing the Impact of Diabetes Mellitus on Donor Corneal Endothelial Cell Density. Cornea. 2017 May;36(5):561-566. doi: 10.1097/ICO.0000000000001174. PubMed PMID: 28306601.
Vislisel JM, Goins KM, Wagoner MD, Schmidt GA, Aldrich BT, Skeie JM, Reed CR, Zimmerman MB, Greiner MA. Incidence and Outcomes of Positive Donor Corneoscleral Rim Fungal Cultures after Keratoplasty. Ophthalmology. 2017 Jan;124(1):36-42. doi: 10.1016/j.ophtha.2016.09.017. Epub 2016 Nov 3. PubMed PMID: 27817919.
Grobe JL. Comprehensive Assessments of Energy Balance in Mice. Methods Mol Biol. 2017;1614:123-146. doi: 10.1007/978-1-4939-7030-8_10. PubMed PMID: 28500600.
Agassandian K, Grobe JL, Liu X, Agassandian M, Thompson AP, Sigmund CD, Cassell MD. Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice. Am J Physiol Regul Integr Comp Physiol. 2017 Jun 1;312(6):R973-R981. doi: 10.1152/ajpregu.00511.2016. Epub 2017 May 10. PubMed PMID: 28490451.
Riedl RA, Atkinson SN, Burnett CML, Grobe JL, Kirby JR. The Gut Microbiome, Energy Homeostasis, and Implications for Hypertension. Curr Hypertens Rep. 2017 Apr;19(4):27. doi: 10.1007/s11906-017-0721-6. Review. PubMed PMID: 28316052.
Claflin KE, Sandgren JA, Lambertz AM, Weidemann BJ, Littlejohn NK, Burnett CM, Pearson NA, Morgan DA, Gibson-Corley KN, Rahmouni K, Grobe JL. Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism. J Clin Invest. 2017 Apr 3;127(4):1414-1424. doi: 10.1172/JCI88641. Epub 2017 Mar 6. PubMed PMID: 28263184; PubMed Central PMCID: PMC5373887.
Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA. Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet. Obesity (Silver Spring). 2016 Oct;24(10):2140-9. doi: 10.1002/oby.21620. Epub 2016 Aug 12. PubMed PMID: 27515998; PubMed Central PMCID: PMC5039085.
Sapouckey SA, Deng G, Sigmund CD, Grobe JL. Potential Mechanisms of Hypothalamic Renin-Angiotensin System Activation by Leptin and DOCA-salt for the Control of Resting Metabolism. Physiol Genomics. 2017 Oct 6:physiolgenomics.00087.2017. doi: 10.1152/physiolgenomics.00087.2017. [Epub ahead of print] PubMed PMID: 28986397.
Chad Grueter, PhD:
Spitler KM, Ponce JM, Oudit GY, Hall DD, Grueter CE. Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming. Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H768-H780. doi: 10.1152/ajpheart.00728.2016. Epub 2017 Feb 3. PubMed PMID: 28159809; PubMed Central PMCID: PMC5407164.
Hall DD, Ponce JM, Chen B, Spitler KM, Alexia A, Oudit GY, Song LS, Grueter CE. Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure. JCI Insight. 2017 Aug 3;2(15). pii: 92476. doi: 10.1172/jci.insight.92476. [Epub ahead of print] PubMed PMID: 28768905.
Isabella Grumbach, MD, PhD:
Sebag SC, Koval OM, Paschke JD, Winters CJ, Jaffer OA, Dworski R, Sutterwala FS, Anderson ME, Grumbach IM. Mitochondrial CaMKII inhibition in airway epithelium protects against allergic asthma. JCI Insight. 2017 Feb 9;2(3):e88297. doi: 10.1172/jci.insight.88297. PubMed PMID: 28194433; PubMed Central PMCID: PMC5291733.
Prasad AM, Ketsawatsomkron P, Nuno DW, Koval OM, Dibbern ME, Venema AN, Sigmund CD, Lamping KG, Grumbach IM. Role of CaMKII in Ang-II-dependent small artery remodeling. Vascul Pharmacol. 2016 Dec;87:172-179. doi: 10.1016/j.vph.2016.09.007. Epub 2016 Sep 20. PubMed PMID: 27658984; PubMed Central PMCID: PMC5164857.
Murthy S, Koval OM, Ramiro Diaz JM, Kumar S, Nuno D, Scott JA, Allamargot C, Zhu LJ, Broadhurst K, Santhana V, Kutschke WJ, Irani K, Lamping KG, Grumbach IM. Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity. PLoS One. 2017 Oct 23;12(10):e0186311. doi: 10.1371/journal.pone.0186311. eCollection 2017. PubMed PMID: 29059213.
Lawrence Hunsicker, MD:
Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428. Diabetes. 2017 Jun 29. pii: db17er09a. doi: 10.2337/db17-er09a. [Epub ahead of print] PubMed PMID: 28663189.
Umanath K, Greco B, Jalal DI, McFadden M, Sika M, Koury MJ, Niecestro R, Hunsicker LG, Greene T, Lewis JB, Dwyer JP. The safety of achieved iron stores and their effect on IV iron and ESA use: post-hoc results from a randomized trial of ferric citrate as a phosphate binder in dialysis . Clin Nephrol. 2017 Mar;87 (2017)(3):124-133. doi: 10.5414/CN108924. PubMed PMID: 28128726.
Jarolim P, Claggett BL, Conrad MJ, Carpenter MA, Ivanova A, Bostom AG, Kusek JW, Hunsicker LG, Jacques PF, Gravens-Mueller L, Finn P, Solomon SD, Weiner DE, Levey AS, Pfeffer MA. B-Type Natriuretic Peptide and Cardiac Troponin I Are Associated With Adverse Outcomes in Stable Kidney Transplant Recipients. Transplantation. 2017 Jan;101(1):182-190. doi: 10.1097/TP.0000000000001080. PubMed PMID: 26910333; PubMed Central PMCID: PMC4956594.
Kalil RS, Carpenter MA, Ivanova A, Gravens-Mueller L, John AA, Weir MR, Pesavento T, Bostom AG, Pfeffer MA, Hunsicker LG. Impact of Hyperuricemia on Long-term Outcomes of Kidney Transplantation: Analysis of the FAVORIT Study. Am J Kidney Dis. 2017 Aug 9. pii: S0272-6386(17)30801-6. doi: 10.1053/j.ajkd.2017.06.013. [Epub ahead of print] PubMed PMID: 28801121.
Yumi Imai, MD:
Ma K, Xiao A, Park SH, Glenn L, Jackson L, Barot T, Weaver JR, Taylor-Fishwick DA, Luci DK, Maloney DJ, Mirmira RG, Imai Y, Nadler JL. 12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets. J Clin Endocrinol Metab. 2017 Aug 1;102(8):2789-2797. doi: 10.1210/jc.2017-00267. PubMed PMID: 28609824; PubMed Central PMCID: PMC5546865.
Kaikobad Irani, MD:
Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. PubMed PMID: 28191886.
Yoon JY, Vikram A, London B, Irani K. Reversible lysine acetylation: Another layer of post-translational regulation of the cardiac sodium channel. Channels (Austin). 2017 Jun 9:1-2. doi: 10.1080/19336950.2017.1340015. [Epub ahead of print] PubMed PMID: 28598266.
Kassan M, Vikram A, Kim YR, Li Q, Kassan A, Patel HH, Kumar S, Gabani M, Liu J, Jacobs JS, Irani K. Corrigendum: Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress. Sci Rep. 2017 Apr 10;7:46123. doi: 10.1038/srep46123. PubMed PMID: 28394317; PubMed Central PMCID: PMC5385967.
Kassan M, Vikram A, Kim YR, Li Q, Kassan A, Patel HH, Kumar S, Gabani M, Liu J, Jacobs JS, Irani K. Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress. Sci Rep. 2017 Feb 9;7:42265. doi: 10.1038/srep42265. PubMed PMID: 28181559; PubMed Central PMCID: PMC5299412.
Kumar S, Kim YR, Vikram A, Naqvi A, Li Q, Kassan M, Kumar V, Bachschmid MM, Jacobs JS, Kumar A, Irani K. Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1714-1719. doi: 10.1073/pnas.1614112114. Epub 2017 Jan 30. PubMed PMID: 28137876; PubMed Central PMCID: PMC5321021.
Nagar H, Jung SB, Ryu MJ, Choi SJ, Piao S, Song HJ, Kang SK, Shin N, Kim DW, Jin SA, Jeong JO, Irani K, Jeon BH, Shong M, Kweon GR, Kim CS. CR6-Interacting Factor 1 Deficiency Impairs Vascular Function by Inhibiting the Sirt1-Endothelial Nitric Oxide Synthase Pathway. Antioxid Redox Signal. 2017 Aug 1;27(4):234-249. doi: 10.1089/ars.2016.6719. Epub 2017 May 24. PubMed PMID: 28117598.
Shafique E, Torina A, Reichert K, Colantuono B, Nur N, Zeeshan K, Ravichandran V, Liu Y, Feng J, Zeeshan K, Benjamin LE, Irani K, Harrington EO, Sellke FW, Abid MR. Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium. Cardiovasc Res. 2017 Feb;113(2):234-246. doi: 10.1093/cvr/cvw249. Epub 2017 Jan 14. PubMed PMID: 28088753; PubMed Central PMCID: PMC5340144.
Kassan M, Vikram A, Li Q, Kim YR, Kumar S, Gabani M, Liu J, Jacobs JS, Irani K. MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1. Sci Rep. 2017 Aug 24;7(1):9308. doi: 10.1038/s41598-017-06721-y. PubMed PMID: 28839162.
Kathleen Janz, EdD:
Harrison F, Goodman A, van Sluijs EMF, Andersen LB, Cardon G, Davey R, Janz KF, Kriemler S, Molloy L, Page AS, Pate R, Puder JJ, Sardinha LB, Timperio A, Wedderkopp N, Jones AP; on behalf the ICAD collaborators. Weather and children's physical activity; how and why do relationships vary between countries? Int J Behav Nutr Phys Act. 2017 May 30;14(1):74. doi: 10.1186/s12966-017-0526-7. PubMed PMID: 28558747; PubMed Central PMCID: PMC5450267.
Janz KF. 2016 The Year That Was: Bone Strength. Pediatr Exerc Sci. 2017 Feb;29(1):23-25. doi: 10.1123/pes.2016-0279. PubMed PMID: 28271807.
Singh B, Vo H, Francis SL, Janz KF, Yack HJ. Changes in Gait over a 30-min Walking Session in Obese Females. Med Sci Sports Exerc. 2017 Mar;49(3):555-562. doi: 10.1249/MSS.0000000000001114. PubMed PMID: 27753742.
Glass NA, Torner JC, Letuchy EM, Burns TL, Janz KF, Eichenberger Gilmore JM, Schlechte JA, Levy SM. Do Visceral or Subcutaneous Fat Influence Peripheral Cortical Bone Strength During Adolescence? A Longitudinal Study. J Bone Miner Res. 2017 Oct 30. doi: 10.1002/jbmr.3325. [Epub ahead of print] PubMed PMID: 29083059.
Alan Johnson, PhD:
Arguelles J, Perillan C, Beltz TG, Xue B, Badaue-Passos D Jr, Vega JA, Johnson AK. The effects of experimental gestational hypertension on maternal blood pressure and fluid intake and pre-weanling hypothalamic neuronal activity. Appetite. 2017 Sep 1;116:65-74. doi: 10.1016/j.appet.2017.04.008. Epub 2017 Apr 12. PubMed PMID: 28411128.
McNeal N, Appleton KM, Johnson AK, Scotti ML, Wardwell J, Murphy R, Bishop C, Knecht A, Grippo AJ. The protective effects of social bonding on behavioral and pituitary-adrenal axis reactivity to chronic mild stress in prairie voles. Stress. 2017 Mar;20(2):175-182. doi: 10.1080/10253890.2017.1295444. Epub 2017 Mar 5. PubMed PMID: 28276805.
Xue B, Yin H, Guo F, Beltz TG, Thunhorst RL, Johnson AK. Maternal Gestational Hypertension-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Renal Denervation or Angiotensin-Converting Enzyme Inhibition in Rat Offspring. Hypertension. 2017 Apr;69(4):669-677. doi: 10.1161/HYPERTENSIONAHA.116.08597. Epub 2017 Feb 21. PubMed PMID: 28223469; PubMed Central PMCID: PMC5344733.
Li Y, Shen XZ, Li L, Zhao TV, Bernstein KE, Johnson AK, Lyden P, Fang J, Shi P. Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation. Stroke. 2017 Jul 11. pii: STROKEAHA.117.017370. doi: 10.1161/STROKEAHA.117.017370. [Epub ahead of print] PubMed PMID: 28698257.
Xue B, Beltz TG, Guo F, Johnson AK. Sex Differences in Maternal Gestational Hypertension-Induced Sensitization of Angiotensin II Hypertension in Rat Offspring: the Protective Effect of Estrogen. Am J Physiol Regul Integr Comp Physiol. 2017 Oct 18:ajpregu.00216.2017. doi: 10.1152/ajpregu.00216.2017. [Epub ahead of print] PubMed PMID: 29046315.
Randy Kardon, MD, PhD:
Ledolter J, Kardon RH. Does Testing More Frequently Shorten the Time to Detect Disease Progression? Transl Vis Sci Technol. 2017 May 1;6(3):1. doi: 10.1167/tvst.6.3.1. eCollection 2017 May. PubMed PMID: 28473945; PubMed Central PMCID: PMC5412967.
Chen JJ, AbouChehade JE, Iezzi R Jr, Leavitt JA, Kardon RH. Optical Coherence Angiographic Demonstration of Retinal Changes From Chronic Optic Neuropathies. Neuroophthalmology. 2017 Jan 27;41(2):76-83. doi: 10.1080/01658107.2016.1275703. eCollection 2017 Apr. PubMed PMID: 28348629; PubMed Central PMCID: PMC5354095.
Aloysius Klingelhutz, PhD:
Gourronc FA, Robertson LW, Klingelhutz AJ. A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor. Environ Sci Pollut Res Int. 2017 Jul 11. doi: 10.1007/s11356-017-9676-z. [Epub ahead of print] PubMed PMID: 28699004.
Gadupudi GS, Klingelhutz AJ, Robertson LW. Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity. Chem Res Toxicol. 2016 Sep 19;29(9):1504-9. doi: 10.1021/acs.chemrestox.6b00172. Epub 2016 Aug 23. PubMed PMID: 27509375.
Kulhankova K, Kinney KJ, Stach JM, Gourronc FA, Grumbach IM, Klingelhutz AJ, Salgado-Pabón W. The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function. Infect Immun. 2017 Dec 11. pii: IAI.00848-17. doi: 10.1128/IAI.00848-17. [Epub ahead of print] PubMed PMID: 29229737.
Anne Kwitek, PhD:
Thomas CP, Mansilla MA, Sompallae R, Mason SO, Nishimura CJ, Kimble MJ, Campbell CA, Kwitek AE, Darbro BW, Stewart ZA, Smith RJ. Screening of Living Kidney Donors for Genetic Diseases Using a Comprehensive Genetic Testing Strategy. Am J Transplant. 2017 Feb;17(2):401-410. doi: 10.1111/ajt.13970. Epub 2016 Aug 24. PubMed PMID: 27434427; PubMed Central PMCID: PMC5297870.
Ma MCJ, Pettus JM, Jakoubek JA, Traxler MG, Clark KC, Mennie AK, Kwitek AE. Contribution of independent and pleiotropic genetic effects in the metabolic syndrome in a hypertensive rat. PLoS One. 2017 Aug 8;12(8):e0182650. doi: 10.1371/journal.pone.0182650. eCollection 2017. PubMed PMID: 28792545; PubMed Central PMCID: PMC5549746.
Martín-Gálvez D, Dunoyer de Segonzac D, Ma MCJ, Kwitek AE, Thybert D, Flicek P. Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat. BMC Genomics. 2017 Dec 22;18(1):986. doi: 10.1186/s12864-017-4351-9. PubMed PMID: 29272997.
Helena Laroche, MD, MS:
Gilbert PA, Laroche HH, Wallace RB, Parker EA, Curry SJ. Extending Work on Rural Health Disparities: A Commentary on Matthews and Colleagues' Report. J Rural Health. 2017 Apr 11. doi: 10.1111/jrh.12241. [Epub ahead of print] PubMed PMID: 28397970.
Laroche HH, Hradek C, Hansen K, Hanks AS, Just DR, Wansink B. Healthy Concessions: High School Students' Responses to Healthy Concession Stand Changes. J Sch Health. 2017 Feb;87(2):98-105. doi: 10.1111/josh.12472. PubMed PMID: 28076924; PubMed Central PMCID: PMC5228366.
Montuclard AL, Park-Mroch J, O'Shea AMJ, Wansink B, Irvin J, Laroche HH. College Cafeteria Signage Increases Water Intake but Water Position on the Soda Dispenser Encourages More Soda Consumption. J Nutr Educ Behav. 2017 Jul 22. pii: S1499-4046(17)30649-8. doi: 10.1016/j.jneb.2017.05.361. [Epub ahead of print] PubMed PMID: 28743437.
Katie Larson Ode, MD, MS:
Yi Y, Norris AW, Wang K, Sun X, Uc A, Moran A, Engelhardt JF, Ode KL. Abnormal Glucose Tolerance in Infants and Young Children with Cystic Fibrosis. Am J Respir Crit Care Med. 2016 Oct 15;194(8):974-980. PubMed PMID: 27447840; PubMed Central PMCID: PMC5067820.
Vitor Lira, PhD:
Yan Z, Kronemberger A, Blomme J, Call JA, Caster HM, Pereira RO, Zhao H, de Melo VU, Laker RC, Zhang M, Lira VA. Exercise leads to unfavourable cardiac remodelling and enhanced metabolic homeostasis in obese mice with cardiac and skeletal muscle autophagy deficiency. Sci Rep. 2017 Aug 11;7(1):7894. doi: 10.1038/s41598-017-08480-2. PubMed PMID: 28801668.
Laker RC, Drake JC, Wilson RJ, Lira VA, Lewellen BM, Ryall KA, Fisher CC, Zhang M, Saucerman JJ, Goodyear LJ, Kundu M, Yan Z. Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat Commun. 2017 Sep 15;8(1):548. doi: 10.1038/s41467-017-00520-9. PubMed PMID: 28916822.
Turner JE, Lira VA, Brum PC. New Insights into the Benefits of Physical Activity and Exercise for Aging and Chronic Disease. Oxid Med Cell Longev. 2017;2017:2503767. doi: 10.1155/2017/2503767. Epub 2017 Oct 8. PubMed PMID: 29118896; PubMed Central PMCID: PMC5651115.
Allyn Mark, MD:
Horwath JA, Hurr C, Butler SD, Guruju M, Cassell MD, Mark AL, Davisson RL, Young CN. Obesity-induced hepatic steatosis is mediated by endoplasmic reticulum stress in the subfornical organ of the brain. JCI Insight. 2017 Apr 20;2(8). pii: 90170. doi: 10.1172/jci.insight.90170. [Epub ahead of print] PubMed PMID: 28422749; PubMed Central PMCID: PMC5396512.
Lob HE, Song J, Hurr C, Chung A, Young CN, Mark AL, Davisson RL. Deletion of p22(phox)-dependent oxidative stress in the hypothalamus protects against obesity by modulating β(3)-adrenergic mechanisms. JCI Insight. 2017 Jan 26;2(2):e87094. doi: 10.1172/jci.insight.87094. PubMed PMID: 28138551; PubMed Central PMCID: PMC5256131.
Kathleen Markan, PhD:
Markan KR, Naber MC, Small SM, Peltekian L, Kessler RL, Potthoff MJ. FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue. Mol Metab. 2017 Mar 27;6(6):602-610. doi: 10.1016/j.molmet.2017.03.009. eCollection 2017 Jun. PubMed PMID: 28580290; PubMed Central PMCID: PMC5444074.
Andrew Norris, MD, PhD:
Coryell WH, Langbehn DR, Norris AW, Yao JR, Dindo LN, Calarge CA. Polyunsaturated fatty acid composition and childhood adversity: Independent correlates of depressive symptom persistence. Psychiatry Res. 2017 Jun 21;256:305-311. doi: 10.1016/j.psychres.2017.06.036. [Epub ahead of print] PubMed PMID: 28666200.
Brian O'Neill, MD, PhD:
Cai W, Sakaguchi M, Kleinridders A, Gonzalez-Del Pino G, Dreyfuss JM, O'Neill BT, Ramirez AK, Pan H, Winnay JN, Boucher J, Eck MJ, Kahn CR. Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Nat Commun. 2017 Mar 27;8:14892. doi: 10.1038/ncomms14892. PubMed PMID: 28345670; PubMed Central PMCID: PMC5378997.
Sakaguchi M, Fujisaka S, Cai W, Winnay JN, Konishi M, O'Neill BT, Li M, García-Martín R, Takahashi H, Hu J, Kulkarni RN, Kahn CR. Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor. Cell Metab. 2017 Feb 7;25(2):448-462. doi: 10.1016/j.cmet.2016.12.008. Epub 2017 Jan 5. PubMed PMID: 28065828; PubMed Central PMCID: PMC5304432.
James HA, O'Neill BT, Nair KS. Insulin Regulation of Proteostasis and Clinical Implications. Cell Metab. 2017 Jul 10. pii: S1550-4131(17)30352-2. doi: 10.1016/j.cmet.2017.06.010. [Epub ahead of print] Review. PubMed PMID: 28712655.
Sakaguchi M, Fujisaka S, Cai W, Winnay JN, Konishi M, O'Neill BT, Li M, García-Martín R, Takahashi H, Hu J, Kulkarni RN, Kahn CR. Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor. Cell Metab. 2017 Feb 7;25(2):448-462. doi: 10.1016/j.cmet.2016.12.008. Epub 2017 Jan 5. PubMed PMID: 28065828; PubMed Central PMCID: PMC5304432.
Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017 Oct 3. pii: 94585. doi: 10.1172/JCI94585. [Epub ahead of print] PubMed PMID: 28972537.
Middelbeek RJW, O'Neill BT, Nishino M, Pallotta JA. Concurrent Intrathyroidal Thyroid Cancer and Thyroid Cancer in Struma Ovarii: A Case Report and Literature Review. J Endocr Soc. 2017 Mar 23;1(5):396-400. doi: 10.1210/js.2017-00052. eCollection 2017 May 1. PubMed PMID: 29264493; PubMed Central PMCID: PMC5686688.
Gary Pierce, PhD:
Pierce GL, Kalil GZ, Ajibewa T, Holwerda SW, Persons J, Moser DJ, Fiedorowicz JG. Anxiety independently contributes to elevated inflammation in humans with obesity. Obesity (Silver Spring). 2017 Feb;25(2):286-289. doi: 10.1002/oby.21698. Epub 2016 Dec 21. PubMed PMID: 28000423; PubMed Central PMCID: PMC5269606.
DuBose LE, Voss MW, Weng TB, Kent JD, Dubishar KM, Lane-Cordova A, Sigurdsson G, Schmid P, Barlow PB, Pierce GL. Carotid β-stiffness index is associated with slower processing speed but not working memory or white matter integrity in healthy middle-aged/older adults. J Appl Physiol (1985). 2017 Apr 1;122(4):868-876. doi: 10.1152/japplphysiol.00769.2016. Epub 2017 Jan 26. PubMed PMID: 28126907; PubMed Central PMCID: PMC5407200.
Santos-Parker JR, Strahler TR, Vorwald VM, Pierce GL, Seals DR. Habitual aerobic exercise does not protect against micro- or macrovascular endothelial dysfunction in healthy estrogen-deficient postmenopausal women. J Appl Physiol (1985). 2017 Jan 1;122(1):11-19. doi: 10.1152/japplphysiol.00732.2016. Epub 2016 Nov 10. PubMed PMID: 27834671; PubMed Central PMCID: PMC5283850.
Casey DP, Ueda K, Wegman-Points LJ, Pierce GL. Muscle contraction induced arterial shear stress increases endothelial nitric oxide synthase phosphorylation in humans. Am J Physiol Heart Circ Physiol. 2017 Aug 11:ajpheart.00282.2017. doi: 10.1152/ajpheart.00282.2017. [Epub ahead of print] PubMed PMID: 28801524.
Pierce GL. Recent Advances: Mechanisms and Subclinical Consequences of Aortic Stiffness. Hypertension. 2017 Sep 5. pii: HYPERTENSIONAHA.117.08933. doi: 10.1161/HYPERTENSIONAHA.117.08933. [Epub ahead of print] Review. PubMed PMID: 28874465.
Rossman MJ, Kaplon RE, Hill SD, McNamara MN, Santos-Parker JR, Pierce GL, Seals DR, Donato AJ. Endothelial Cell Senescence with Aging in Healthy Humans: Prevention by Habitual Exercise and Relation to Vascular Endothelial Function. Am J Physiol Heart Circ Physiol. 2017 Sep 29:ajpheart.00416.2017. doi: 10.1152/ajpheart.00416.2017. [Epub ahead of print] PubMed PMID: 28971843.
Pierce GL. Aortic Stiffness in Aging and Hypertension: Prevention and Treatment with Habitual Aerobic Exercise. Curr Hypertens Rep. 2017 Oct 18;19(11):90. doi: 10.1007/s11906-017-0788-0. Review. PubMed PMID: 29046980.
Lane-Cordova AD, Kalil GZ, Wagner CJ, Sindler AL, Fiedorowicz JG, Ajibewa T, Haynes WG, Pierce GL. Hemoglobin A1c and C-reactive protein are independently associated with blunted nocturnal blood pressure dipping in obesity-related prediabetes. Hypertens Res. 2017 Oct 26. doi: 10.1038/hr.2017.82. [Epub ahead of print] PubMed PMID: 29070829.
Robert Piper, PhD:
MacDonald C, Winistorfer S, Pope RM, Wright ME, Piper RC. Enzyme reversal to explore the function of yeast E3 ubiquitin-ligases. Traffic. 2017 Jul;18(7):465-484. doi: 10.1111/tra.12485. Epub 2017 Jun 1. PubMed PMID: 28382714.
MacDonald C, Piper RC. Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases. J Cell Biol. 2017 Aug 2. pii: jcb.201702177. doi: 10.1083/jcb.201702177. [Epub ahead of print] PubMed PMID: 28768685.
Xu P, Hankins HM, MacDonald C, Erlinger SJ, Frazier MN, Diab NS, Piper RC, Jackson LP, MacGurn JA, Graham TR. COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal. Elife. 2017 Oct 23;6. pii: e28342. doi: 10.7554/eLife.28342. [Epub ahead of print] PubMed PMID: 29058666.
Pearson G, Chai B, Vozheiko T, Liu X, Kandarpa M, Piper RC, Soleimanpour SA. Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex that Regulates Beta Cell Mitophagy. Diabetes. 2017 Nov 27. pii: db170321. doi: 10.2337/db17-0321. [Epub ahead of print] PubMed PMID: 29180353.
Philip Polgreen, MD, MPH:
Anthony CA, Peterson RA, Polgreen LA, Sewell DK, Polgreen PM. The Seasonal Variability in Surgical Site Infections and the Association With Warmer Weather: A Population-Based Investigation. Infect Control Hosp Epidemiol. 2017 Jul;38(7):809-816. doi: 10.1017/ice.2017.84. Epub 2017 May 16. PubMed PMID: 28506327.
Peterson RA, Polgreen LA, Cavanaugh JE, Polgreen PM. Increasing Incidence, Cost, and Seasonality in Patients Hospitalized for Cellulitis. Open Forum Infect Dis. 2017 Feb 8;4(1):ofx008. doi: 10.1093/ofid/ofx008. eCollection 2017 Winter. PubMed PMID: 28480281; PubMed Central PMCID: PMC5414024.
Simmering JE, Tang F, Cavanaugh JE, Polgreen LA, Polgreen PM. The Increase in Hospitalizations for Urinary Tract Infections and the Associated Costs in the United States, 1998-2011. Open Forum Infect Dis. 2017 Feb 24;4(1):ofw281. doi: 10.1093/ofid/ofw281. eCollection 2017 Winter. PubMed PMID: 28480273; PubMed Central PMCID: PMC5414046.
Matthew Potthoff, PhD:
BonDurant LD, Ameka M, Naber MC, Markan KR, Idiga SO, Acevedo MR, Walsh SA, Ornitz DM, Potthoff MJ. FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms. Cell Metab. 2017 Apr 4;25(4):935-944.e4. doi: 10.1016/j.cmet.2017.03.005. PubMed PMID: 28380381; PubMed Central PMCID: PMC5494834.
Søberg S, Sandholt CH, Jespersen NZ, Toft U, Madsen AL, von Holstein-Rathlou S, Grevengoed TJ, Christensen KB, Bredie WLP, Potthoff MJ, Solomon TPJ, Scheele C, Linneberg A, Jørgensen T, Pedersen O, Hansen T, Gillum MP, Grarup N. FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans. Cell Metab. 2017 May 2;25(5):1045-1053.e6. doi: 10.1016/j.cmet.2017.04.009. PubMed PMID: 28467924.
Potthoff MJ. FGF21 and metabolic disease in 2016: A new frontier in FGF21 biology. Nat Rev Endocrinol. 2017 Feb;13(2):74-76. doi: 10.1038/nrendo.2016.206. Epub 2016 Dec 16. PubMed PMID: 27983736.
Kamal Rahmouni, PhD:
Contreras C, Nogueiras R, Diéguez C, Rahmouni K, López M. Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway. Redox Biol. 2017 Aug;12:854-863. doi: 10.1016/j.redox.2017.04.019. Epub 2017 Apr 15. Review. PubMed PMID: 28448947; PubMed Central PMCID: PMC5406580.
Reho JJ, Rahmouni K. Oxidative and inflammatory signals in obesity-associated vascular abnormalities. Clin Sci (Lond). 2017 Jun 30;131(14):1689-1700. doi: 10.1042/CS20170219. Print 2017 Jul 15. Review. PubMed PMID: 28667067.
Martínez-Sánchez N, Seoane-Collazo P, Contreras C, Varela L, Villarroya J, Rial-Pensado E, Buqué X, Aurrekoetxea I, Delgado TC, Vázquez-Martínez R, González-García I, Roa J, Whittle AJ, Gomez-Santos B, Velagapudi V, Tung YCL, Morgan DA, Voshol PJ, Martínez de Morentin PB, López-González T, Liñares-Pose L, Gonzalez F, Chatterjee K, Sobrino T, Medina-Gómez G, Davis RJ, Casals N, Orešič M, Coll AP, Vidal-Puig A, Mittag J, Tena-Sempere M, Malagón MM, Diéguez C, Martínez-Chantar ML, Aspichueta P, Rahmouni K, Nogueiras R, Sabio G, Villarroya F, López M. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance. Cell Metab. 2017 Jul 5;26(1):212-229.e12. doi: 10.1016/j.cmet.2017.06.014. PubMed PMID: 28683288.
Flak JN, Arble D, Pan W, Patterson C, Lanigan T, Goforth PB, Sacksner J, Joosten M, Morgan DA, Allison MB, Hayes J, Feldman E, Seeley RJ, Olson DP, Rahmouni K, Myers MG Jr. A leptin-regulated circuit controls glucose mobilization during noxious stimuli. J Clin Invest. 2017 Jul 17. pii: 90147. doi: 10.1172/JCI90147. [Epub ahead of print] PubMed PMID: 28714862.
Douris N, Desai BN, Fisher FM, Cisu T, Fowler AJ, Zarebidaki E, Nguyen NLT, Morgan DA, Bartness TJ, Rahmouni K, Flier JS, Maratos-Flier E. Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice. Mol Metab. 2017 Jun 6;6(8):854-862. doi: 10.1016/j.molmet.2017.05.017. eCollection 2017 Aug. PubMed PMID: 28752049; PubMed Central PMCID: PMC5518722.
Jiang J, Cui H, Rahmouni K. Optogenetics and Pharmacogenetics: Principles and Applications. Am J Physiol Regul Integr Comp Physiol. 2017 Aug 9:ajpregu.00091.2017. doi: 10.1152/ajpregu.00091.2017. [Epub ahead of print] PubMed PMID: 28794102.
Lan T, Morgan DA, Rahmouni K, Sonoda J, Fu X, Burgess SC, Holland WL, Kliewer SA, Mangelsdorf DJ. FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia. Cell Metab. 2017 Oct 5. pii: S1550-4131(17)30556-9. doi: 10.1016/j.cmet.2017.09.005. [Epub ahead of print] PubMed PMID: 28988823.
Chhabra KH, Morgan DA, Tooke BP, Adams JM, Rahmouni K, Low MJ. Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice. Mol Metab. 2017 Oct;6(10):1274-1285. doi: 10.1016/j.molmet.2017.07.005. Epub 2017 Jul 17. PubMed PMID: 29031726.
Jennifer Robinson, MD, MPH:
Sacks FM, Lichtenstein AH, Wu JHY, Appel LJ, Creager MA, Kris-Etherton PM, Miller M, Rimm EB, Rudel LL, Robinson JG, Stone NJ, Van Horn LV; American Heart Association. Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association. Circulation. 2017 Jun 15. pii: CIR.0000000000000510. doi: 10.1161/CIR.0000000000000510. [Epub ahead of print] Review. PubMed PMID: 28620111.
Robinson JG. Reply: Cost Effectiveness of Nonstatin-to-Statin Therapy. J Am Coll Cardiol. 2017 Apr 18;69(15):1996. doi: 10.1016/j.jacc.2017.01.056. PubMed PMID: 28408035.
Harris WS, Luo J, Pottala JV, Espeland MA, Margolis KL, Manson JE, Wang L, Brasky TM, Robinson JG. Red blood cell polyunsaturated fatty acids and mortality in the Women's Health Initiative Memory Study. J Clin Lipidol. 2017 Jan - Feb;11(1):250-259.e5. doi: 10.1016/j.jacl.2016.12.013. Epub 2017 Jan 12. PubMed PMID: 28391893.
Espeland MA, Crimmins EM, Grossardt BR, Crandall JP, Gelfond JA, Harris TB, Kritchevsky SB, Manson JE, Robinson JG, Rocca WA, Temprosa M, Thomas F, Wallace R, Barzilai N; Multimorbidity Clinical Trials Consortium. Clinical Trials Targeting Aging and Age-Related Multimorbidity. J Gerontol A Biol Sci Med Sci. 2017 Mar 1;72(3):355-361. doi: 10.1093/gerona/glw220. PubMed PMID: 28364543.
Stone NJ, Robinson JG. Potential for Net Benefit Should Guide Preventive Therapy. Circulation. 2017 Feb 14;135(7):630-632. doi: 10.1161/CIRCULATIONAHA.116.022147. PubMed PMID: 28193796.
Robinson JG, Rosenson RS, Farnier M, Chaudhari U, Sasiela WJ, Merlet L, Miller K, Kastelein JJ. Safety of Very Low Low-Density Lipoprotein Cholesterol Levels With Alirocumab: Pooled Data From Randomized Trials. J Am Coll Cardiol. 2017 Feb 7;69(5):471-482. doi: 10.1016/j.jacc.2016.11.037. PubMed PMID: 28153102.
Persons JE, Robinson JG, Payne ME, Fiedorowicz JG. Serum lipid changes following the onset of depressive symptoms in postmenopausal women. Psychiatry Res. 2017 Jan;247:282-287. doi: 10.1016/j.psychres.2016.12.006. Epub 2016 Dec 5. PubMed PMID: 27940323.
Gaudet D, Watts GF, Robinson JG, Minini P, Sasiela WJ, Edelberg J, Louie MJ, Raal FJ. Effect of Alirocumab on Lipoprotein(a) Over ≥1.5 Years (from the Phase 3 ODYSSEY Program). Am J Cardiol. 2017 Jan 1;119(1):40-46. doi: 10.1016/j.amjcard.2016.09.010. Epub 2016 Sep 29. PubMed PMID: 27793396.
Spracklen CN, Smith CJ, Saftlas AF, Triche EW, Bjonnes A, Keating BJ, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia. Hypertens Pregnancy. 2017 Feb;36(1):30-35. doi: 10.1080/10641955.2016.1223303. Epub 2016 Sep 22. PubMed PMID: 27657194.
Spracklen CN, Ryckman KK, Robinson JG, Stefanick ML, Sarto GE, Anton SD, Wallace RB. Low Birth Weight and Risk of Later-Life Physical Disability in Women. J Gerontol A Biol Sci Med Sci. 2017 Apr 1;72(4):543-547. doi: 10.1093/gerona/glw134. PubMed PMID: 27440911.
Robinson JG, Huijgen R, Ray K, Persons J, Kastelein JJ, Pencina MJ. Determining When to Add Nonstatin Therapy: A Quantitative Approach. J Am Coll Cardiol. 2016 Dec 6;68(22):2412-2421. doi: 10.1016/j.jacc.2016.09.928. Review. PubMed PMID: 27908345.
Farnier M, Colhoun HM, Sasiela WJ, Edelberg JM, Asset G, Robinson JG. Long-term treatment adherence to the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab in 6 ODYSSEY Phase III clinical studies with treatment duration of 1 to 2 years. J Clin Lipidol. 2017 Jun 8. pii: S1933-2874(17)30342-2. doi: 10.1016/j.jacl.2017.05.016. [Epub ahead of print] PubMed PMID: 28693998.
Robinson JG, Rosenson RS, Farnier M, Chaudhari U, Sasiela WJ, Merlet L, Miller K, Kastelein JJ. Safety of Very Low Low-Density Lipoprotein Cholesterol Levels With Alirocumab: Pooled Data From Randomized Trials. J Am Coll Cardiol. 2017 Feb 7;69(5):471-482. doi: 10.1016/j.jacc.2016.11.037. PubMed PMID: 28153102.
Giugliano RP, Mach F, Zavitz K, Kurtz C, Im K, Kanevsky E, Schneider J, Wang H, Keech A, Pedersen TR, Sabatine MS, Sever PS, Robinson JG, Honarpour N, Wasserman SM, Ott BR; EBBINGHAUS Investigators. Cognitive Function in a Randomized Trial of Evolocumab. N Engl J Med. 2017 Aug 17;377(7):633-643. doi: 10.1056/NEJMoa1701131. PubMed PMID: 28813214.
Korhonen MJ, Robinson JG, Annis IE, Hickson RP, Bell JS, Hartikainen J, Fang G. Adherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction. J Am Coll Cardiol. 2017 Sep 26;70(13):1543-1554. doi: 10.1016/j.jacc.2017.07.783. PubMed PMID: 28935030.
Fang G, Annis IE, Farley JF, Mahendraratnam N, Hickson RP, Stürmer T, Robinson JG. Incidence of and Risk Factors for Severe Adverse Events in Elderly Patients Taking Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers after an Acute Myocardial Infarction. Pharmacotherapy. 2017 Oct 23. doi: 10.1002/phar.2051. [Epub ahead of print] PubMed PMID: 29059475.
Hickson RP, Robinson JG, Annis IE, Killeya-Jones LA, Korhonen MJ, Cole AL, Fang G. Changes in Statin Adherence Following an Acute Myocardial Infarction Among Older Adults: Patient Predictors and the Association With Follow-Up With Primary Care Providers and/or Cardiologists. J Am Heart Assoc. 2017 Oct 19;6(10). pii: e007106. doi: 10.1161/JAHA.117.007106. PubMed PMID: 29051213.
Navar AM, Wang TY, Li S, Robinson JG, Goldberg AC, Virani S, Roger VL, Wilson PWF, Elassal J, Lee LV, Peterson ED. Lipid management in contemporary community practice: Results from the Provider Assessment of Lipid Management (PALM) Registry. Am Heart J. 2017 Nov;193:84-92. doi: 10.1016/j.ahj.2017.08.005. Epub 2017 Aug 12. PubMed PMID: 29129260.
Graham I, Shear C, De Graeff P, Boulton C, Catapano AL, Stough WG, Carlsson SC, De Backer G, Emmerich J, Greenfeder S, Kim AM, Lautsch D, Nguyen T, Nissen SE, Prasad K, Ray K, Robinson JG, Sasiela WJ, Bruins Slot K, Stroes E, Thuren T, Van der Schueren B, Velkovski-Rouyer M, Wasserman SM, Wiklund O, Zouridakis E. New Strategies for the Development of Lipid Lowering Therapies to Reduce Cardiovascular Risk. Eur Heart J Cardiovasc Pharmacother. 2017 Nov 28. doi: 10.1093/ehjcvp/pvx031. [Epub ahead of print] PubMed PMID: 29194462.
Robert Roghair, MD:
Haskell SE, Lo C, Kent ME, Eggleston TM, Volk KA, Reinking BE, Roghair RD. Cardiac Outcomes after Perinatal Sertraline Exposure in Mice. J Cardiovasc Pharmacol. 2017 Apr 25. doi: 10.1097/FJC.0000000000000501. [Epub ahead of print] PubMed PMID: 28459713.
Meyer LR, Dexter B, Lo C, Kenkel E, Hirai T, Roghair RD, Haskell SE. Perinatal SSRI exposure permanently alters cerebral serotonin receptor mRNA in mice but does not impact adult behaviors. J Matern Fetal Neonatal Med. 2017 Apr 24:1-9. doi: 10.1080/14767058.2017.1317342. [Epub ahead of print] PubMed PMID: 28385052.
Stephen Russell, MD:
Nathaniel Roybal C, Sledz E, Elshatory Y, Zhang L, Almeida DRP, Chin EK, Critser B, Abramoff MD, Russell SR. DYSFUNCTIONAL AUTONOMIC REGULATION OF THE CHOROID IN CENTRAL SEROUS CHORIORETINOPATHY. Retina. 2017 May 9. doi: 10.1097/IAE.0000000000001677. [Epub ahead of print] PubMed PMID: 28489693.
Tom Rutkowski, PhD:
DeZwaan-McCabe D, Sheldon RD, Gorecki MC, Guo DF, Gansemer ER, Kaufman RJ, Rahmouni K, Gillum MP, Taylor EB, Teesch LM, Rutkowski DT. ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis. Cell Rep. 2017 May 30;19(9):1794-1806. doi: 10.1016/j.celrep.2017.05.020. PubMed PMID: 28564599.
Rajan Sah, MD, PhD:
Zhang Y, Xie L, Gunasekar SK, Tong D, Mishra A, Gibson WJ, Wang C, Fidler T, Marthaler B, Klingelhutz A, Abel ED, Samuel I, Smith JK, Cao L, Sah R. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nat Cell Biol. 2017 May;19(5):504-517. doi: 10.1038/ncb3514. Epub 2017 Apr 24. PubMed PMID: 28436964; PubMed Central PMCID: PMC5415409.
Zhang Y, Tong D, Mishra A, Xie L, Samuel I, Smith JK, Sah R. Isolation and Patch-Clamp of Primary Adipocytes. Methods Mol Biol. 2017;1566:145-150. doi: 10.1007/978-1-4939-6820-6_14. PubMed PMID: 28244048.
Abiria SA, Krapivinsky G, Sah R, Santa-Cruz AG, Chaudhuri D, Zhang J, Adstamongkonkul P, DeCaen PG, Clapham DE. TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles. Proc Natl Acad Sci U S A. 2017 Jul 10. pii: 201707380. doi: 10.1073/pnas.1707380114. [Epub ahead of print] PubMed PMID: 28696294.
Xie L, Zhang Y, Gunasekar S, Mishra A, Cao L, Sah R. Induction of adipose and hepatic SWELL1 expression is required for maintaining systemic insulin-sensitivity in obesity. Channels (Austin). 2017 Sep 5:0. doi: 10.1080/19336950.2017.1373225. [Epub ahead of print] PubMed PMID: 28873008
Patrick Schlievert, PhD:
Herrera A, Kulhankova K, Sonkar VK, Dayal S, Klingelhutz AJ, Salgado-Pabón W, Schlievert PM. Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities. MBio. 2017 Mar 21;8(2). pii: e00273-17. doi: 10.1128/mBio.00273-17. PubMed PMID: 28325766; PubMed Central PMCID: PMC5362035.
Gillman AN, Breshears LM, Kistler CK, Finnegan PM, Torres VJ, Schlievert PM, Peterson ML. Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa. Toxins (Basel). 2017 Jun 28;9(7). pii: E202. doi: 10.3390/toxins9070202. PubMed PMID: 28657583.
Tuffs SW, James DBA, Bestebroer J, Richards AC, Goncheva MI, O'Shea M, Wee BA, Seo KS, Schlievert PM, Lengeling A, van Strijp JA, Torres VJ, Fitzgerald JR. The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function. PLoS Pathog. 2017 Sep 7;13(9):e1006461. doi: 10.1371/journal.ppat.1006461. eCollection 2017 Sep. PubMed PMID: 28880920.
Julien Sebag, PhD:
Rouault AAJ, Srinivasan DK, Yin TC, Lee AA, Sebag JA. Melanocortin Receptor Accessory Proteins (MRAPs): Functions in the Melanocortin System and Beyond. Biochim Biophys Acta. 2017 May 9. pii: S0925-4439(17)30145-X. doi: 10.1016/j.bbadis.2017.05.008. [Epub ahead of print] Review. PubMed PMID: 28499989.
Rouault AAJ, Lee AA, Sebag JA. Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling. Biochim Biophys Acta. 2017 Sep 19. pii: S0167-4889(17)30251-3. doi: 10.1016/j.bbamcr.2017.09.008. [Epub ahead of print] PubMed PMID: 28939058.
Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD. Hypertension-Causing Mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-κB p65 in Vascular Smooth Muscle. Hypertension. 2017 Jul;70(1):174-182. doi: 10.1161/HYPERTENSIONAHA.117.09276. Epub 2017 May 15. PubMed PMID: 28507170; PubMed Central PMCID: PMC5472224.
Nakagawa P, Sigmund CD. How Is the Brain Renin-Angiotensin System Regulated? Hypertension. 2017 Jul;70(1):10-18. doi: 10.1161/HYPERTENSIONAHA.117.08550. Epub 2017 May 30. Review. PubMed PMID: 28559391.
Sigmund CD, Diz DI, Chappell MC. No Brain Renin-Angiotensin System: Déjà vu All Over Again? Hypertension. 2017 Jun;69(6):1007-1010. doi: 10.1161/HYPERTENSIONAHA.117.09167. Epub 2017 Apr 10. PubMed PMID: 28396531; PubMed Central PMCID: PMC5497704.
Hu C, Keen HL, Lu KT, Liu X, Wu J, Davis DR, Ibeawuchi SC, Vogel S, Quelle FW, Sigmund CD. Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin. JCI Insight. 2017 Mar 23;2(6):e91738. doi: 10.1172/jci.insight.91738. PubMed PMID: 28352663; PubMed Central PMCID: PMC5358481.
Agassandian K, Grobe JL, Liu X, Agassandian M, Thompson AP, Sigmund CD, Cassell MD. Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice. Am J Physiol Regul Integr Comp Physiol. 2017 Jun 1;312(6):R973-R981. doi: 10.1152/ajpregu.00511.2016. Epub 2017 May 10. PubMed PMID: 28490451; PubMed Central PMCID: PMC5495920.
Shinohara K, Nakagawa P, Gomez J, Morgan DA, Littlejohn NK, Folchert MD, Weidemann BJ, Liu X, Walsh SA, Ponto LL, Rahmouni K, Grobe JL, Sigmund CD. Selective Deletion of Renin-b in the Brain Alters Drinking and Metabolism. Hypertension. 2017 Sep 5. pii: HYPERTENSIONAHA.117.09923. doi: 10.1161/HYPERTENSIONAHA.117.09923. [Epub ahead of print] PubMed PMID: 28874461.
Woll AW, Quelle FW, Sigmund CD. PPARγ and Retinol Binding Protein 7 Form a Regulatory Hub Promoting Antioxidant Properties of the Endothelium. Physiol Genomics. 2017 Sep 15:physiolgenomics.00055.2017. doi: 10.1152/physiolgenomics.00055.2017. [Epub ahead of print] PubMed PMID: 28916634.
Ferdaus MZ, Miller LN, Agbor LN, Saritas T, Singer JD, Sigmund CD, McCormick JA. Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects. JCI Insight. 2017 Dec 21;2(24). pii: 96700. doi: 10.1172/jci.insight.96700. [Epub ahead of print] PubMed PMID: 29263298.
William Sivitz, MD:
Fink BD, Guo DF, Kulkarni CA, Rahmouni K, Kerns RJ, Sivitz WI. Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice. Pharmacol Res Perspect. 2017 Mar 10;5(2):e00301. doi: 10.1002/prp2.301. eCollection 2017 Apr. PubMed PMID: 28357127; PubMed Central PMCID: PMC5368965.
Fink BD, Bai F, Yu L, Sivitz WI. Regulation of ATP Production: Dependences on Calcium Concentration and Respiratory State. Am J Physiol Cell Physiol. 2017 May 17:ajpcell.00086.2017. doi: 10.1152/ajpcell.00086.2017. [Epub ahead of print]PubMed PMID: 28515085.
Purnell JQ, Braffett BH, Zinman B, Gubitosi-Klug RA, Sivitz W, Bantle JP, Ziegler G, Cleary PA, Brunzell JD; DCCT/EDIC Research Group. Impact of Excessive Weight Gain on Cardiovascular Outcomes in Type 1 Diabetes: Results From the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes Care. 2017 Dec;40(12):1756-1762. doi: 10.2337/dc16-2523. PubMed PMID: 29138273.
Diane Slusarski, BA, BS, PhD:
Scott CA, Marsden AN, Rebagliati MR, Zhang Q, Chamling X, Searby CC, Baye LM, Sheffield VC, Slusarski DC. Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein. PLoS Genet. 2017 Jul 28;13(7):e1006936. doi: 10.1371/journal.pgen.1006936. [Epub ahead of print] PubMed PMID: 28753627.
Marsden AN, Derry SW, Schneider I, Scott CA, Westfall TA, Brastrom LK, Shea M, Dawson DV, Slusarski DC. The Nkd EF-Hand Domain Modulates Divergent Wnt Signaling Outputs in Zebrafish. Dev Biol. 2017 Nov 24. pii: S0012-1606(17)30461-X. doi: 10.1016/j.ydbio.2017.11.012. [Epub ahead of print] PubMed PMID: 29180104.
Linda Snetselaar, RD, PhD:
Zhang N, Campo S, Yang J, Eckler P, Snetselaar L, Janz K, Leary E. What Motivates Young Adults to Talk About Physical Activity on Social Network Sites? J Med Internet Res. 2017 Jun 22;19(6):e226. doi: 10.2196/jmir.7017. PubMed PMID: 28642215.
Hayden KM, Beavers DP, Steck SE, Hebert JR, Tabung FK, Shivappa N, Casanova R, Manson JE, Padula CB, Salmoirago-Blotcher E, Snetselaar LG, Zaslavsky O, Rapp SR. The association between an inflammatory diet and global cognitive function and incident dementia in older women: The Women's Health Initiative Memory Study. Alzheimers Dement. 2017 May 19. pii: S1552-5260(17)30185-1. doi: 10.1016/j.jalz.2017.04.004. [Epub ahead of print] PubMed PMID: 28531379.
Prentice RL, Aragaki AK, Van Horn L, Thomson CA, Beresford SA, Robinson J, Snetselaar L, Anderson GL, Manson JE, Allison MA, Rossouw JE, Howard BV. Low-fat dietary pattern and cardiovascular disease: results from the Women's Health Initiative randomized controlled trial. Am J Clin Nutr. 2017 Jul;106(1):35-43. doi: 10.3945/ajcn.117.153270. Epub 2017 May 17. PubMed PMID: 28515068.
Ford C, Chang S, Vitolins MZ, Fenton JI, Howard BV, Rhee JJ, Stefanick M, Chen B, Snetselaar L, Urrutia R, Frazier-Wood AC. Evaluation of diet pattern and weight gain in postmenopausal women enrolled in the Women's Health Initiative Observational Study. Br J Nutr. 2017 Apr;117(8):1189-1197. doi: 10.1017/S0007114517000952. Epub 2017 May 16. PubMed PMID: 28509665.
Tabung FK, Steck SE, Ma Y, Liese AD, Zhang J, Lane DS, Ho GYF, Hou L, Snetselaar L, Ockene JK, Hebert JR. Changes in the inflammatory potential of diet over time and risk of colorectal cancer in postmenopausal women. Am J Epidemiol. 2017 May 9. doi: 10.1093/aje/kwx115. [Epub ahead of print] PubMed PMID: 28486621.
Zaslavsky O, Zelber-Sagi S, Hebert JR, Steck SE, Shivappa N, Tabung FK, Wirth MD, Bu Y, Shikany JM, Orchard T, Wallace RB, Snetselaar L, Tinker LF. Biomarker-calibrated nutrient intake and healthy diet index associations with mortality risks among older and frail women from the Women's Health Initiative. Am J Clin Nutr. 2017 Jun;105(6):1399-1407. doi: 10.3945/ajcn.116.151530. Epub 2017 Apr 19. PubMed PMID: 28424183; PubMed Central PMCID: PMC5445680.
Quach A, Levine ME, Tanaka T, Lu AT, Chen BH, Ferrucci L, Ritz B, Bandinelli S, Neuhouser ML, Beasley JM, Snetselaar L, Wallace RB, Tsao PS, Absher D, Assimes TL, Stewart JD, Li Y, Hou L, Baccarelli AA, Whitsel EA, Horvath S. Epigenetic clock analysis of diet, exercise, education, and lifestyle factors. Aging (Albany NY). 2017 Feb 14;9(2):419-446. doi: 10.18632/aging.101168. PubMed PMID: 28198702; PubMed Central PMCID: PMC5361673.
Zaslavsky O, Li W, Going S, Datta M, Snetselaar L, Zelber-Sagi S. Association between body composition and hip fractures in older women with physical frailty. Geriatr Gerontol Int. 2017 Jun;17(6):898-904. doi: 10.1111/ggi.12798. Epub 2016 May 10. PubMed PMID: 27164296; PubMed Central PMCID: PMC5104679.
Martinez JA, Wertheim BC, Thomson CA, Bea JW, Wallace R, Allison M, Snetselaar L, Chen Z, Nassir R, Thompson PA. Physical Activity Modifies the Association between Dietary Protein and Lean Mass of Postmenopausal Women. J Acad Nutr Diet. 2017 Feb;117(2):192-203.e1. doi: 10.1016/j.jand.2016.10.009. Epub 2016 Nov 30. PubMed PMID: 27914915; PubMed Central PMCID: PMC5276713.
Ford C, Chang S, Vitolins MZ, Fenton JI, Howard BV, Rhee JJ, Stefanick M, Chen B, Snetselaar L, Urrutia R, Frazier-Wood AC. Evaluation of diet pattern and weight gain in postmenopausal women enrolled in the Women's Health Initiative Observational Study. Br J Nutr. 2017 Apr;117(8):1189-1197. doi: 10.1017/S0007114517000952. Epub 2017 May 16. PubMed PMID: 28509665.
Yuan C, Qian ZR, Babic A, Morales-Oyarvide V, Rubinson DA, Kraft P, Ng K, Bao Y, Giovannucci EL, Ogino S, Stampfer MJ, Gaziano JM, Sesso HD, Buring JE, Cochrane BB, Chlebowski RT, Snetselaar LG, Manson JE, Fuchs CS, Wolpin BM. Prediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival. J Clin Oncol. 2016 Aug 20;34(24):2899-905. doi: 10.1200/JCO.2015.66.3005. Epub 2016 Jun 20. PubMed PMID: 27325858; PubMed Central PMCID: PMC5012662.
Thomson CA, Crane TE, Garcia DO, Wertheim BC, Hingle M, Snetselaar L, Datta M, Rohan T, LeBlanc E, Chlebowski RT, Qi L. Association between Dietary Energy Density and Obesity-Associated Cancer: Results from the Women's Health Initiative. J Acad Nutr Diet. 2017 Aug 8. pii: S2212-2672(17)30624-X. doi: 10.1016/j.jand.2017.06.010. [Epub ahead of print] PubMed PMID: 28826845.
Elliott Sohn, MD:
Burnight ER, Gupta M, Wiley LA, Anfinson KR, Tran A, Triboulet R, Hoffmann JM, Klaahsen DL, Andorf JL, Jiao C, Sohn EH, Adur MK, Ross JW, Mullins RF, Daley GQ, Schlaeger TM, Stone EM, Tucker BA. Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration. Mol Ther. 2017 Jun 12. pii: S1525-0016(17)30233-2. doi: 10.1016/j.ymthe.2017.05.015. [Epub ahead of print] PubMed PMID: 28619647.
Mullins RF, Warwick AN, Sohn EH, Lotery AJ. From Compliment to Insult-Genetics of the Complement System in Physiology and Disease in the Human Retina. Hum Mol Genet. 2017 May 8. doi: 10.1093/hmg/ddx181. [Epub ahead of print] PubMed PMID: 28482029.
Chirco KR, Sohn EH, Stone EM, Tucker BA, Mullins RF. Structural and molecular changes in the aging choroid: implications for age-related macular degeneration. Eye (Lond). 2017 Jan;31(1):10-25. doi: 10.1038/eye.2016.216. Epub 2016 Oct 7. Review. PubMed PMID: 27716746; PubMed Central PMCID: PMC5233940.
Campochiaro PA, Lauer AK, Sohn EH, Mir TA, Naylor S, Anderton MC, Kelleher M, Harrop R, Ellis S, Mitrophanous KA. Lentiviral Vector Gene Transfer of Endostatin/Angiostatin for Macular Degeneration (GEM) Study. Hum Gene Ther. 2017 Jan;28(1):99-111. doi: 10.1089/hum.2016.117. Epub 2016 Sep 26. PubMed PMID: 27710144; PubMed Central PMCID: PMC5278797.
Russell S, Bennett J, Wellman JA, Chung DC, Yu ZF, Tillman A, Wittes J, Pappas J, Elci O, McCague S, Cross D, Marshall KA, Walshire J, Kehoe TL, Reichert H, Davis M, Raffini L, George LA, Hudson FP, Dingfield L, Zhu X, Haller JA, Sohn EH, Mahajan VB, Pfeifer W, Weckmann M, Johnson C, Gewaily D, Drack A, Stone E, Wachtel K, Simonelli F, Leroy BP, Wright JF, High KA, Maguire AM. Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial. Lancet. 2017 Jul 13. pii: S0140-6736(17)31868-8. doi: 10.1016/S0140-6736(17)31868-8. [Epub ahead of print] PubMed PMID: 28712537.
Chirco KR, Sohn EH, Stone EM, Tucker BA, Mullins RF. Structural and molecular changes in the aging choroid: implications for age-related macular degeneration. Eye (Lond). 2017 Jan;31(1):10-25. doi: 10.1038/eye.2016.216. Epub 2016 Oct 7. Review. PubMed PMID: 27716746; PubMed Central PMCID: PMC5233940.
Jiao C, Eliott D, Spee C, He S, Wang K, Mullins RF, Hinton DR, Sohn EH. APOPTOSIS AND ANGIOFIBROSIS IN DIABETIC TRACTIONAL MEMBRANES AFTER VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: Results of a Prospective Trial. Report No. 2. Retina. 2017 Nov 22. doi: 10.1097/IAE.0000000000001952. [Epub ahead of print] PubMed PMID: 29190236.
Long-Sheng Song, MD, MS
Guo Y, VanDusen NJ, Zhang L, Gu W, Sethi I, Guatimosim S, Ma Q, Jardin BD, Ai Y, Zhang D, Chen B, Guo A, Yuan GC, Song LS, Pu WT. Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo. Circ Res. 2017 Jun 9;120(12):1874-1888. doi: 10.1161/CIRCRESAHA.116.310283. Epub 2017 Mar 29. Review. PubMed PMID: 28356340; PubMed Central PMCID: PMC5466492.
Liu W, Deng J, Ding W, Wang G, Shen Y, Zheng J, Zhang X, Luo Y, Lv C, Wang Y, Chen L, Yan D, Boudreau RL, Song LS, Liu J. Decreased KCNE2 Expression Participates in the Development of Cardiac Hypertrophy by Regulation of Calcineurin-NFAT (Nuclear Factor of Activated T Cells) and Mitogen-Activated Protein Kinase Pathways. Circ Heart Fail. 2017 Jun;10(6). pii: e003960. doi: 10.1161/CIRCHEARTFAILURE.117.003960. PubMed PMID: 28611128.
Zhang C, Chen B, Wang Y, Guo A, Tang Y, Khataei T, Shi Y, Kutschke WJ, Zimmerman K, Weiss RM, Liu J, Benson CJ, Hong J, Ma J, Song LS. MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress. J Mol Cell Cardiol. 2017 Aug 16. pii: S0022-2828(17)30288-2. doi: 10.1016/j.yjmcc.2017.08.007. [Epub ahead of print] PubMed PMID: 28822805.
Milan Sonka, PhD:
Miri MS, Abràmoff MD, Kwon YH, Sonka M, Garvin MK. A machine-learning graph-based approach for 3D segmentation of Bruch's membrane opening from glaucomatous SD-OCT volumes. Med Image Anal. 2017 Jul;39:206-217. doi: 10.1016/j.media.2017.04.007. Epub 2017 May 6. PubMed PMID: 28528295.
Kovarnik T, Chen Z, Wahle A, Zhang L, Skalicka H, Kral A, Lopez JJ, Horak J, Sonka M, Linhart A. Pathologic Intimal Thickening Plaque Phenotype: Not as Innocent as Previously Thought. A Serial 3D Intravascular Ultrasound Virtual Histology Study. Rev Esp Cardiol (Engl Ed). 2017 Jan;70(1):25-33. doi: 10.1016/j.rec.2016.04.058. Epub 2016 Sep 5. English, Spanish. PubMed PMID: 27615562.
Zhang L, Wahle A, Chen Z, Lopez JJ, Kovarnik T, Sonka M. Predicting Locations of High-Risk Plaques in Coronary Arteries in Patients Receiving Statin Therapy. IEEE Trans Med Imaging. 2017 Jul 11. doi: 10.1109/TMI.2017.2725443. [Epub ahead of print] PubMed PMID: 28708548.
Klimscha S, Waldstein SM, Schlegl T, Bogunovic H, Sadeghipour A, Philip AM, Podkowinski D, Pablik E, Zhang L, Abramoff MD, Sonka M, Gerendas BS, Schmidt-Erfurth U. Spatial Correspondence Between Intraretinal Fluid, Subretinal Fluid, and Pigment Epithelial Detachment in Neovascular Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):4039-4048. doi: 10.1167/iovs.16-20201. PubMed PMID: 28813577.
Xiang D, Bagci U, Jin C, Shi F, Zhu W, Yao J, Sonka M, Chen X. CorteXpert: A model-based method for automatic renal cortex segmentation. Med Image Anal. 2017 Aug 23;42:257-273. doi: 10.1016/j.media.2017.06.010. [Epub ahead of print] PubMed PMID: 28888170.
Kovarnik T, Chen Z, Mintz GS, Wahle A, Bayerova K, Kral A, Chval M, Kopriva K, Lopez J, Sonka M, Linhart A. Plaque volume and plaque risk profile in diabetic vs. non-diabetic patients undergoing lipid-lowering therapy: a study based on 3D intravascular ultrasound and virtual histology. Cardiovasc Diabetol. 2017 Dec 7;16(1):156. doi: 10.1186/s12933-017-0637-0. PubMed PMID: 29212544.
Douglas Spitz, PhD:
Zahra A, Fath MA, Opat E, Mapuskar KA, Bhatia SK, Ma DC, Iii SNR, Snyders TP, Chenard CA, Eichenberger-Gilmore JM, Bodeker KL, Ahmann L, Smith BJ, Vollstedt SA, Brown HA, Hejleh TA, Clamon GH, Berg DJ, Szweda LI, Spitz DR, Buatti JM, Allen BG. Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer: The University of Iowa Experience of Two Phase 1 Clinical Trials. Radiat Res. 2017 Jun;187(6):743-754. doi: 10.1667/RR14668.1. Epub 2017 Apr 24. PubMed PMID: 28437190.
Schibler J, Tomanek-Chalkley AM, Reedy JL, Zhan F, Spitz DR, Schultz MK, Goel A. Mitochondrial Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells. PLoS One. 2016 Nov 30;11(11):e0167323. doi: 10.1371/journal.pone.0167323. eCollection 2016. PubMed PMID: 27902770; PubMed Central PMCID: PMC5130279.
Mapuskar KA, Flippo KH, Schoenfeld JD, Riley DP, Strack S, Abu-Hejleh T, Furqan M, Monga V, Domann FE, Buatti JM, Goswami PC, Spitz DR, Allen BG. Mitochondrial superoxide increases age-associated susceptibility of human dermal fibroblasts to radiation and chemotherapy. Cancer Res. 2017 Aug 1. pii: canres.0106.2017. doi: 10.1158/0008-5472.CAN-17-0106. [Epub ahead of print] PubMed PMID: 28765155.
Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, Monga V, Bodeker KL, Ahmann L, Vollstedt S, Brown H, Kauffman EPS, Schall ME, Hohl RJ, Clamon GH, Greenlee JD, Howard MA, Schultz MK, Smith BJ, Riley DP, Domann FE, Cullen JJ, Buettner GR, Buatti JM, Spitz DR, Allen BG. O(2)(⋅-) and H(2)O(2)-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer Cell. 2017 Aug 14;32(2):268. doi: 10.1016/j.ccell.2017.07.008. PubMed PMID: 28810149.
Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biol. 2017 Aug 26;14:82-87. doi: 10.1016/j.redox.2017.08.017. [Epub ahead of print] PubMed PMID: 28886484.
Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Bradley MD, Wagner BA, Buettner GR, Monga V, Milhem M, Spitz DR, Allen BG. Redox active metals and H(2)O(2) mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models. Redox Biol. 2017 Sep 28;14:417-422. doi: 10.1016/j.redox.2017.09.012. [Epub ahead of print] PubMed PMID: 29069637; PubMed Central PMCID: PMC5651553.
Paemka L, McCullagh BN, Abou Alaiwa MH, Stoltz DA, Dong Q, Randak CO, Gray RD, McCray PB Jr. Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth. J Cyst Fibros. 2017 Jul;16(4):471-474. doi: 10.1016/j.jcf.2017.03.007. Epub 2017 Apr 1. PubMed PMID: 28377087.
Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA. CF airway smooth muscle transcriptome reveals a role for PYK2. JCI Insight. 2017 Sep 7;2(17). pii: 95332. doi: 10.1172/jci.insight.95332. [Epub ahead of print] PubMed PMID: 28878137.
Gray RD, Hardisty G, Regan KH, Smith M, Robb CT, Duffin R, Mackellar A, Felton JM, Paemka L, McCullagh BN, Lucas CD, Dorward DA, McKone EF, Cooke G, Donnelly SC, Singh PK, Stoltz DA, Haslett C, McCray PB, Whyte MKB, Rossi AG, Davidson DJ. Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis. Thorax. 2017 Sep 15. pii: thoraxjnl-2017-210134. doi: 10.1136/thoraxjnl-2017-210134. [Epub ahead of print] PubMed PMID: 28916704.
Li X, Vargas Buonfiglio LG, Adam RJ, Stoltz DA, Zabner J, Comellas AP. Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs. Crit Care Med. 2017 Dec;45(12):e1240-e1246. doi: 10.1097/CCM.0000000000002720. PubMed PMID: 28953499; PubMed Central PMCID: PMC5693779.
Stefan Strack, PhD:
Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM. SK2 channels regulate mitochondrial respiration and mitochondrial Ca(2+) uptake. Cell Death Differ. 2017 May;24(5):761-773. doi: 10.1038/cdd.2017.2. Epub 2017 Mar 10. PubMed PMID: 28282037; PubMed Central PMCID: PMC5423111.
Flippo KH, Strack S. Mitochondrial dynamics in neuronal injury, development and plasticity. J Cell Sci. 2017 Feb 15;130(4):671-681. doi: 10.1242/jcs.171017. Epub 2017 Feb 2. Review. PubMed PMID: 28154157; PubMed Central PMCID: PMC5339882.
Morita M, Prudent J, Basu K, Goyon V, Katsumura S, Hulea L, Pearl D, Siddiqui N, Strack S, McGuirk S, St-Pierre J, Larsson O, Topisirovic I, Vali H, McBride HM, Bergeron JJ, Sonenberg N. mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. Mol Cell. 2017 Sep 13. pii: S1097-2765(17)30610-X. doi: 10.1016/j.molcel.2017.08.013. [Epub ahead of print] PubMed PMID: 28918902.
Ji WK, Chakrabarti R, Fan X, Schoenfeld L, Strack S, Higgs HN. Receptor-mediated Drp1 oligomerization on endoplasmic reticulum. J Cell Biol. 2017 Nov 20. pii: jcb.201610057. doi: 10.1083/jcb.201610057. [Epub ahead of print] PubMed PMID: 29158231.
Eric Taylor, PhD:
Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN. The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol. 2017 Jun 9. doi: 10.1113/EP086380. [Epub ahead of print] PubMed PMID: 28597936.
Taylor EB. Functional Properties of the Mitochondrial Carrier System. Trends Cell Biol. 2017 May 15. pii: S0962-8924(17)30062-4. doi: 10.1016/j.tcb.2017.04.004. [Epub ahead of print] Review. PubMed PMID: 28522206.
Rauckhorst AJ, Gray LR, Sheldon RD, Fu X, Pewa AD, Feddersen CR, Dupuy AJ, Gibson-Corley KN, Cox JE, Burgess SC, Taylor EB. The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity. Mol Metab. 2017 Nov;6(11):1468-1479. doi: 10.1016/j.molmet.2017.09.002. Epub 2017 Sep 18. PubMed PMID: 29107293.
Eva Tsalikian, MD:
Saggar M, Tsalikian E, Mauras N, Mazaika P, White NH, Weinzimer S, Buckingham B, Hershey T, Reiss AL; Diabetes Research in Children Network (DirecNet). Compensatory Hyperconnectivity in Developing Brains of Young Children With Type 1 Diabetes. Diabetes. 2017 Mar;66(3):754-762. doi: 10.2337/db16-0414. Epub 2016 Oct 4. PubMed PMID: 27702833; PubMed Central PMCID: PMC5319714.
Aliya Uc, MD:
Uc A, Fishman DS. Pancreatic Disorders. Pediatr Clin North Am. 2017 Jun;64(3):685-706. doi: 10.1016/j.pcl.2017.01.010. Review. PubMed PMID: 28502446.
Giefer MJ, Lowe ME, Werlin SL, Zimmerman B, Wilschanski M, Troendle D, Schwarzenberg SJ, Pohl JF, Palermo J, Ooi CY, Morinville VD, Lin TK, Husain SZ, Himes R, Heyman MB, Gonska T, Gariepy CE, Freedman SD, Fishman DS, Bellin MD, Barth B, Abu-El-Haija M, Uc A. Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations. J Pediatr. 2017 Jul;186:95-100. doi: 10.1016/j.jpeds.2017.03.063. Epub 2017 May 10. PubMed PMID: 28502372.
Scheers I, Palermo JJ, Freedman S, Wilschanski M, Shah U, Abu-El-Haija M, Barth B, Fishman DS, Gariepy C, Giefer MJ, Heyman MB, Himes RW, Husain SZ, Lin TK, Liu Q, Lowe M, Mascarenhas M, Morinville V, Ooi CY, Perito ER, Piccoli DA, Pohl JF, Schwarzenberg SJ, Troendle D, Werlin S, Zimmerman B, Uc A, Gonska T. Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management. Am J Gastroenterol. 2017 Apr 4. doi: 10.1038/ajg.2017.85. [Epub ahead of print] PubMed PMID: 28374818.
Gariepy CE, Heyman MB, Lowe ME, Pohl JF, Werlin SL, Wilschanski M, Barth B, Fishman DS, Freedman SD, Giefer MJ, Gonska T, Himes R, Husain SZ, Morinville VD, Ooi CY, Schwarzenberg SJ, Troendle DM, Yen E, Uc A. Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group. J Pediatr Gastroenterol Nutr. 2017 Jan;64(1):95-103. doi: 10.1097/MPG.0000000000001446. PubMed PMID: 27782962; PubMed Central PMCID: PMC5191966.
Abu-El-Haija M, Kumar S, Quiros JA, Balakrishnan K, Barth B, Bitton S, Eisses JF, Foglio EJ, Fox V, Francis D, Freeman AJ, Gonska T, Grover AS, Husain SZ, Kumar R, Lapsia S, Lin T, Liu QY, Maqbool A, Sellers ZM, Szabo F, Uc A, Werlin SL, Morinville VD. The Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report from the NASPGHAN Pancreas Committee. J Pediatr Gastroenterol Nutr. 2017 Aug 23. doi: 10.1097/MPG.0000000000001715. [Epub ahead of print] PubMed PMID: 28837512.
Yuriy Usachev, PhD:
Sugiyama D, Kang S, Arpey N, Arunakul P, Usachev YM, Brennan TJ. H2O2 Induces Muscle Nociception via Transient Receptor Potential Ankyrin 1 Receptors. Anesthesiology. 2017 Jun 21. doi: 10.1097/ALN.0000000000001756. [Epub ahead of print] PubMed PMID: 28640016.
Warwick CA, Usachev YM. Culture, Transfection, and Immunocytochemical Analysis of Primary Macrophages. Methods Mol Biol. 2017;1554:161-173. doi: 10.1007/978-1-4939-6759-9_9. PubMed PMID: 28185189.
Michael Welsh, MD:
Hisert KB, Heltshe SL, Pope C, Jorth P, Wu X, Edwards RM, Radey M, Accurso FJ, Wolter DJ, Cooke G, Adam RJ, Carter S, Grogan B, Launspach JL, Donnelly SC, Gallagher CG, Bruce JE, Stoltz DA, Welsh MJ, Hoffman LR, McKone EF, Singh PK. Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections. Am J Respir Crit Care Med. 2017 Jun 15;195(12):1617-1628. doi: 10.1164/rccm.201609-1954OC. PubMed PMID: 28222269.
Ramsey BW, Welsh MJ. AJRCCM: 100-Year Anniversary. Progress along the Pathway of Discovery Leading to Treatment and Cure of Cystic Fibrosis. Am J Respir Crit Care Med. 2017 May 1;195(9):1092-1099. doi: 10.1164/rccm.201702-0266ED. PubMed PMID: 28459323; PubMed Central PMCID: PMC5439020.
Ling Yang, PhD:
Nicholas R.L. Lind, Qingwen Qian, Ling Yang. ER stress and autophagy in obesity and nonalcoholic fatty liver disease. Current Pathology Reports, 2017, published online, DOI: 10.1007/s40139-017-0145-7.
Mark Yorek, PhD:
Davidson EP, Coppey LJ, Shevalye H, Obrosov A, Kardon RH, Yorek MA. Impaired Corneal Sensation and Nerve Loss in a Type 2 Rat Model of Chronic Diabetes Is Reversible With Combination Therapy of Menhaden Oil, α-Lipoic Acid, and Enalapril. Cornea. 2017 Jun;36(6):725-731. doi: 10.1097/ICO.0000000000001182. PubMed PMID: 28476051; PubMed Central PMCID: PMC5421399.
Yorek MS, Obrosov A, Shevalye H, Coppey LJ, Kardon RH, Yorek MA. Early vs. late intervention of high fat/low dose streptozotocin treated C57Bl/6J mice with enalapril, α-lipoic acid, menhaden oil or their combination: Effect on diabetic neuropathy related endpoints. Neuropharmacology. 2017 Apr;116:122-131. doi: 10.1016/j.neuropharm.2016.12.022. Epub 2016 Dec 23. PubMed PMID: 28025096; PubMed Central PMCID: PMC5385152.
Yorek MA. Is Fish Oil a Potential Treatment for Diabetic Peripheral Neuropathy? Curr Diabetes Rev. 2017 May 22. doi: 10.2174/1573399813666170522155327. [Epub ahead of print] PubMed PMID: 28530530.
Qi W, Keenan HA, Li Q, Ishikado A, Kannt A, Sadowski T, Yorek MA, Wu IH, Lockhart S, Coppey LJ, Pfenninger A, Liew CW, Qiang G, Burkart AM, Hastings S, Pober D, Cahill C, Niewczas MA, Israelsen WJ, Tinsley L, Stillman IE, Amenta PS, Feener EP, Vander Heiden MG, Stanton RC, King GL. Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nat Med. 2017 Jun;23(6):753-762. doi: 10.1038/nm.4328. Epub 2017 Apr 24. PubMed PMID: 28436957.
Obrosov A, Shevalye H, Coppey LJ, Yorek MA. Effect of tempol on peripheral neuropathy in diet-induced obese and high-fat fed/low-dose streptozotocin-treated C57Bl6/J mice. Free Radic Res. 2017 Apr;51(4):360-367. doi: 10.1080/10715762.2017.1315767. Epub 2017 Apr 19. PubMed PMID: 28376643.
Nicholas Zavazava, MD:
Manzar GS, Kim EM, Zavazava N. Demethylation of Induced Pluripotent Stem Cells from Type 1 Diabetic Patients Enhances Differentiation into Functional Pancreatic β-cells. J Biol Chem. 2017 Mar 30. pii: jbc.M117.784280. doi: 10.1074/jbc.M117.784280. [Epub ahead of print] PubMed PMID: 28360105.
Kim EM, Manzar G, Zavazava N. Induced pluripotent stem cell-derived gamete-associated proteins incite rejection of induced pluripotent stem cells in syngeneic mice. Immunology. 2017 Jun;151(2):191-197. doi: 10.1111/imm.12722. Epub 2017 Mar 22. PubMed PMID: 28185259.
Diana Zepeda-Orozco, MD:
Zepeda-Orozco D, Wen HM, Hamilton BA, Raikwar NS, Thomas CP. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep. 2017 Sep;5(18). pii: e13453. doi: 10.14814/phy2.13453. Epub 2017 Sep 27. PubMed PMID: 28963126.
Denice Zingman, MD:
Palamaner Subash Shantha G, Bhave PD, Girotra S, Hodgson-Zingman D, Mazur A, Giudici M, Chrischilles E, Vaughan Sarrazin MS. Sex-Specific Comparative Effectiveness of Oral Anticoagulants in Elderly Patients With Newly Diagnosed Atrial Fibrillation. Circ Cardiovasc Qual Outcomes. 2017 Apr;10(4). pii: e003418. doi: 10.1161/CIRCOUTCOMES.116.003418. PubMed PMID: 28408716; PubMed Central PMCID: PMC5412710.