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Featured 2020 Publications of FOEDRC Members

E. Dale Abel, MD, PhD: 

  • Li X, Wu J, Sun X, Wu Q, Li Y, Li K, Zhang Q, Li Y, Abel ED, Chen H. Autophagy Reprograms Alveolar Progenitor Cell Metabolism in Response to Lung Injury. Stem Cell Reports. 2020 Mar 10;14(3):420-432. doi: 10.1016/j.stemcr.2020.01.008. Epub 2020 Feb 13. PMID: 32059792; PMCID: PMC7066233
  • Shanmugam G, Wang D, Gounder SS, Fernandes J, Litovsky SH, Whitehead K, Radhakrishnan RK, Franklin S, Hoidal J, Kensler TW, Dell'Italia L, Darley-Usmar V, Abel ED, Jones DP, Ping P, Namakkal Soorappan R. Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction. Antioxid Redox Signal. 2020 Feb 16:10.1089/ars.2019.7808. doi: 10.1089/ars.2019.7808. Epub ahead of print. PMID: 3206489
  • Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED. Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling. JCI Insight. 2020 Mar 26;5(6):e134920. doi: 10.1172/jci.insight.134920. PMID: 32213702; PMCID: PMC7213803.
  • Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE. Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. J Am Heart Assoc. 2020 Apr 7;9(7):e014366. doi: 10.1161/JAHA.119.014366. Epub 2020 Apr 4. PMID: 32248761.
  • Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Thodou Krokidi A, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG. The Role of Non-Glycolytic Glucose Metabolism in Myocardial Recovery upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure. Circulation. 2020 Apr 30. doi: 10.1161/CIRCULATIONAHA.119.044452. Epub ahead of print. PMID: 32351122.
  • Wende AR, Schell JC, Ha CM, Pepin ME, Khalimonchuk O, Schwertz H, Pereira RO, Brahma MK, Tuinei J, Contreras-Ferrat A, Wang L, Andrizzi CA, Olsen CD, Bradley WE, Dell'Italia LJ, Dillmann WH, Litwin SE, Abel ED. Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction. Diabetes. 2020 May 4:db191057. doi: 10.2337/db19-1057. Epub ahead of print. PMID: 32366681.
  • Veys K, Fan Z, Ghobrial M, Bouché A, García-Caballero M, Vriens K, Conchinha NV, Seuwen A, Schlegel F, Gorski T, Crabbé M, Gilardoni P, Ardicoglu R, Schaffenrath J, Casteels C, De Smet G, Smolders I, Van Laere K, Abel ED, Fendt SM, Schroeter A, Kalucka J, Cantelmo AR, Wälchli T, Keller A, Carmeliet P, De Bock K. Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity. Circ Res. 2020 May 14. doi: 10.1161/CIRCRESAHA.119.316463. Epub ahead of print. PMID: 32404031.
  • Ritchie RH, Abel ED. Basic Mechanisms of Diabetic Heart Disease. Circ Res. 2020 May 22;126(11):1501-1525. doi: 10.1161/CIRCRESAHA.120.315913. Epub 2020 May 21. PMID: 32437308.
  • Contat C, Ancey PB, Zangger N, Sabatino S, Pascual J, Escrig S, Jensen L, Goepfert C, Lanz B, Lepore M, Gruetter R, Rossier A, Berezowska S, Neppl C, Zlobec I, Clerc-Rosset S, Knott GW, Rathmell JC, Abel ED, Meibom A, Meylan E. Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth. Elife. 2020 Jun 23;9. pii: e53618. doi: 10.7554/eLife.53618. PubMed PMID: 32571479; PubMed Central PMCID: PMC7311173.
  • Li B, Lee WC, Song C, Ye L, Abel ED, Long F. Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation. FASEB J. 2020 Jul 6. doi: 10.1096/fj.202000771R. [Epub ahead of print] PubMed PMID: 32627870.
  • Brahma MK, Ha CM, Pepin ME, Mia S, Sun Z, Chatham JC, Habegger KM, Abel ED, Paterson AJ, Young ME, Wende AR. Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization. J Am Heart Assoc. 2020 Aug 4;9(15):e013039. doi: 10.1161/JAHA.119.013039. Epub 2020 Jul 30. PMID: 32750298.
  • Kumar A, Xie L, Ta CM, Hinton AO, Gunasekar SK, Minerath RA, Shen K, Maurer JM, Grueter CE, Abel ED, Meyer G, Sah R. SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism. Elife. 2020 Sep 15;9:e58941. doi: 10.7554/eLife.58941. PMID: 32930093; PMCID: PMC7541086.
  • Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Mitochondrial pyruvate carriers are required for myocardial stress adaptation. Nat Metab. 2020 Nov;2(11):1248-1264. doi: 10.1038/s42255-020-00288-1. Epub 2020 Oct 26. Erratum in: Nat Metab. 2020 Nov 18;: PMID: 33106689.
  • Tang M, Park SH, Petri S, Yu H, Rueda CB, Abel ED, Kim CY, Hillman EMC, Li F, Lee Y, Ding L, Jagadish S, Frankel WN, De Vivo DC, Monani UR. An early endothelial cell-specific requirement for Glut1 is revealed in Glut1 deficiency syndrome model mice. JCI Insight. 2020 Dec 22:145789. doi: 10.1172/jci.insight.145789. Epub ahead of print. PMID: 33351789.

Michael Abramoff, MD, PhD: 

  • Channa R, Wolf R, Abramoff MD. Autonomous Artificial Intelligence in Diabetic  Retinopathy: From Algorithm to Clinical Application. J Diabetes Sci Technol. 2020Mar 4:1932296820909900. doi: 10.1177/1932296820909900. [Epub ahead of print] PubMed PMID: 32126819.
  • Abramoff MD, Leng T, Ting DSW, Rhee K, Horton MB, Brady CJ, Chiang MF. Automated and Computer-Assisted Detection, Classification, and Diagnosis of Diabetic Retinopathy. Telemed J E Health. 2020 Mar 16. doi: 10.1089/tmj.2020.0008. [Epub ahead of print] PubMed PMID: 32209008.
  • van de Kreeke JA, Darma S, Chan Pin Yin JMPL, Tan HS, Abramoff MD, Twisk JWR, Verbraak FD. The spatial relation of diabetic retinal neurodegeneration with diabetic retinopathy. PLoS One. 2020 Apr 16;15(4):e0231552. doi: 10.1371/journal.pone.0231552. eCollection 2020. PubMed PMID: 32298369; PubMed Central PMCID: PMC7161968.
  • Folk JC, Abràmoff MD. Evaluation and Care of Patients with Diabetic Retinopathy. N Engl J Med. 2020 Jul 30;383(5):e31. doi: 10.1056/NEJMc2018871. PMID: 32726543.
  • Wolf RM, Channa R, Abramoff MD, Lehmann HP. Cost-effectiveness of Autonomous Point-of-Care Diabetic Retinopathy Screening for Pediatric Patients With Diabetes. JAMA Ophthalmol. 2020 Sep 3;138(10):1–7. doi: 10.1001/jamaophthalmol.2020.3190. Epub ahead of print. PMID: 32880616; PMCID: PMC7489415.
  • Singh RP, Hom GL, Abramoff MD, Campbell JP, Chiang MF; AAO Task Force on Artificial Intelligence. Current Challenges and Barriers to Real-World Artificial Intelligence Adoption for the Healthcare System, Provider, and the Patient. Transl Vis Sci Technol. 2020 Aug 11;9(2):45. doi: 10.1167/tvst.9.2.45. PMID: 32879755; PMCID: PMC7443115.
  • Char DS, Abràmoff MD, Feudtner C. Identifying Ethical Considerations for Machine Learning Healthcare Applications. Am J Bioeth. 2020 Nov;20(11):7-17. doi: 10.1080/15265161.2020.1819469. PMID: 33103967.
  • Sun JK, Aiello LP, Abràmoff MD, Antonetti DA, Dutta S, Pragnell M, Levine SR, Gardner TW. Updating the Staging System for Diabetic Retinal Disease. Ophthalmology. 2020 Nov 17:S0161-6420(20)31005-8. doi: 10.1016/j.ophtha.2020.10.008. Epub ahead of print. PMID: 33218709.

Christopher Adams, MD, PhD:

  • Ebert SM, Bullard SA, Basisty N, Marcotte GR, Skopec ZP, Dierdorff JM, Al-Zougbi A, Tomcheck KC, DeLau AD, Rathmacher JA, Bodine SC, Schilling B, Adams  CM. Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by  forming a heterodimer with the transcriptional regulator C/EBPβ. J Biol Chem. 2020 Jan 17. pii: jbc.RA119.012095. doi: 10.1074/jbc.RA119.012095. [Epub ahead of print] PubMed PMID: 31953319.
  • Rasmussen BB, Adams CM. ATF4 Is a Fundamental Regulator of Nutrient Sensing and Protein Turnover. J Nutr. 2020 Mar 19. pii: nxaa067. doi: 10.1093/jn/nxaa067. [Epub ahead of print] PubMed PMID: 32190894.

Ferhaan Ahmad, MD, PhD

  • Simon MA, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K, Schelbert EB, Sullivan LM, Weinberg JM. Equity, Diversity, and Inclusiveness in Cardiovascular Medicine and Healthcare. J Am Heart Assoc. 2020 Sep 17:e018288. doi: 10.1161/JAHA.120.019137. Epub ahead of print. PMID: 32941102.
  • London B, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K, Schelbert EB, Simon MA, Sullivan LM, Weinberg JM. Diversity, Equity, and Inclusiveness in Medicine and Cardiology: Next Steps for JAHA. J Am Heart Assoc. 2020 Sep 17:e018288. doi: 10.1161/JAHA.120.019307. Epub ahead of print. PMID: 32941090.
  • Simon MA, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K, Schelbert EB, Sullivan LM, Weinberg JM. Equity, Diversity, and Inclusiveness in Cardiovascular Medicine and Health Care. J Am Heart Assoc. 2020 Oct 20;9(20):e019137. doi: 10.1161/JAHA.120.019137. Epub 2020 Sep 17. PMID: 32941102.
  • London B, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K, Schelbert EB, Simon MA, Sullivan LM, Weinberg JM. Diversity, Equity, and Inclusiveness in Medicine and Cardiology: Next Steps for JAHA. J Am Heart Assoc. 2020 Oct 20;9(20):e019307. doi: 10.1161/JAHA.120.019307. Epub 2020 Sep 17. PMID: 32941090.

Ethan Anderson, PhD:

Nelson MM, Efird J, Kew KA, Katunga LA, Monroe TB, Doorn JJ, Beatty CN, Shi Q, Akhter S, Alwair H, Robidoux J, Anderson EJ. Enhanced catecholamine flux and impaired carbonyl metabolism disrupt cardiac mitochondrial OxPHOS in diabetes patients. Antioxid Redox Signal. 2020 Oct 16. doi: 10.1089/ars.2020.8122. Epub ahead of print. PMID: 33066717.

James Ankrum, PhD: 

  • Moll G, Hoogduijn MJ, Ankrum JA. Editorial: Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies. Front Immunol. 2020 Feb 18;11:243. doi: 10.3389/fimmu.2020.00243. eCollection 2020. PubMed PMID: 32133010; PubMed Central PMCID: PMC7040069.
  • Burand AJ Jr, Di L, Boland LK, Boyt DT, Schrodt MV, Santillan DA, Ankrum JA. Aggregation of Human Mesenchymal Stromal Cells Eliminates Their Ability to Suppress Human T Cells. Front Immunol. 2020 Feb 25;11:143. doi: 10.3389/fimmu.2020.00143. eCollection 2020. PubMed PMID: 32158443; PubMed Central PMCID: PMC7052295.
  • Boyt DT, Boland LK, Burand AJ Jr, Brown AJ, Ankrum JA. Dose and duration of interferon γ pre-licensing interact with donor characteristics to influence the expression and function of indoleamine-2,3-dioxygenase in mesenchymal stromal cells. J R Soc Interface. 2020 Jun;17(167):20190815. doi: 10.1098/rsif.2019.0815. Epub 2020 Jun 17. PubMed PMID: 32546114.
  • El-Hattab MY, Nagumo Y, Gourronc FA, Klingelhutz AJ, Ankrum JA, Sander EA. Human Adipocyte Conditioned Medium Promotes In Vitro Fibroblast Conversion to Myofibroblasts. Sci Rep. 2020 Jun 24;10(1):10286. doi: 10.1038/s41598-020-67175-3. PubMed PMID: 32581231; PubMed Central PMCID: PMC7314785.

Deniz Atasoy, PhD: 

  • Aklan I, Sayar Atasoy N, Yavuz Y, Ates T, Coban I, Koksalar F, Filiz G, Topcu IC, Oncul M, Dilsiz P, Cebecioglu U, Alp MI, Yilmaz B, Davis DR, Hajdukiewicz K, Saito K, Konopka W, Cui H, Atasoy D. NTS Catecholamine Neurons Mediate Hypoglycemic Hunger via Medial Hypothalamic Feeding Pathways. Cell Metab. 2020 Feb 4;31(2):313-326.e5. doi: 10.1016/j.cmet.2019.11.016. Epub 2019 Dec 12. PMID: 31839488.

Wei Bao, MD, PhD: 

  • Li M, Rahman ML, Wu J, Ding M, Chavarro JE, Lin Y, Ley SH, Bao W, Grunnet LG, Hinkle SN, Thuesen ACB, Yeung E, Gore-Langton RE, Sherman S, Hjort L, Kampmann FB, Bjerregaard AA, Damm P, Tekola-Ayele F, Liu A, Mills JL, Vaag A, Olsen SF, Hu FB, Zhang C. Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations. BMJ Open Diabetes Res Care. 2020 Jan;8(1):e000850. doi: 10.1136/bmjdrc-2019-000850. PMID: 31958311.
  • ​Rong S, Wang L, Peng Z, Liao Y, Li D, Yang X, Nuessler AK, Liu L, Bao W, Yang W. The mechanisms and treatments for sarcopenia: could exosomes be a perspective research strategy in the future? J Cachexia Sarcopenia Muscle. 2020 Jan 27;10.1002/jcsm.12536. doi: 10.1002/jcsm.12536. [Epub ahead of print]. PMID: 31989804.
  • Ley SH, Chavarro JE, Li M, Bao W, Hinkle SN, Wander PL, Rich-Edwards J, Olsen S, Vaag A, Damm P, Grunnet LG, Mills JL, Hu FB, Zhang C. Lactation Duration and Long-term Risk for Incident Type 2 Diabetes in Women With a History of Gestational Diabetes Mellitus. Diabetes Care. 2020 Feb 10:dc192237. doi: 10.2337/dc19-2237. Epub ahead of print. PMID: 32041900.
  • Peng X, Xu Z, Mo X, Guo Q, Yin J, Xu M, Peng Z, Sun T, Zhou L, Peng X, Xu S, Yang W, Bao W, Shan Z, Li X, Liu L. Association of plasma β-amyloid 40 and 42 concentration with type 2 diabetes among Chinese adults. Diabetologia. 2020 Feb 7:10.1007/s00125-020-05102-x. doi: 10.1007/s00125-020-05102-x. Epub ahead of print. PMID: 32034441.
  • Snyder BM, Baer RJ, Oltman SP, Robinson JG, Breheny PJ, Saftlas AF, Bao W, Greiner AL, Carter KD, Rand L, Jelliffe-Pawlowski LL, Ryckman KK. Early pregnancy prediction of gestational diabetes mellitus risk using prenatal screening biomarkers in nulliparous women. Diabetes Res Clin Pract. 2020 Apr 6;163:108139. doi: 10.1016/j.diabres.2020.108139. [Epub ahead of print] PubMed PMID: 32272192.
  • Sun Y, Liu B, Smith JK, Correia MLG, Jones DL, Zhu Z, Taiwo A, Morselli LL, Robinson K, Hart AA, Snetselaar LG, Bao W. Association of Preoperative Body Weight and Weight Loss With Risk of Death After Bariatric Surgery. JAMA Netw Open. 2020 May 1;3(5):e204803. doi: 10.1001/jamanetworkopen.2020.4803. PubMed PMID: 32407504; PubMed Central PMCID: PMC7225906.
  • Gao C, Liu Y, Gan Y, Bao W, Peng X, Xing Q, Gao H, Lai J, Liu L, Wang Z, Yang Y. Effects of fish oil supplementation on glucose control and lipid levels among patients with type 2 diabetes mellitus: a Meta-analysis of randomized controlled trials. Lipids Health Dis. 2020 May 8;19(1):87. doi: 10.1186/s12944-020-01214-w. PubMed PMID: 32384902; PubMed Central PMCID: PMC7206824.
  • Chen G, Li Y, Zeng F, Deng G, Liang J, Wang J, Su Y, Chen Y, Mao L, Liu Z, Bao W, Zhang Z. Biomarkers of fatty acids and risk of type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies. Crit Rev Food Sci Nutr. 2020 Jun 29:1-14. doi: 10.1080/10408398.2020.1784839. Epub ahead of print. PMID: 32598176.
  • Xu J, Hussain S, Lu G, Zheng K, Wei S, Bao W, Zhang L. Associations of Stay-at-Home Order and Face-Masking Recommendation with Trends in Daily New Cases and Deaths of Laboratory-Confirmed COVID-19 in the United States. Explor Res Hypothesis Med. 2020 Jul 8:1-10. doi: 10.14218/ERHM.2020.00045. PMID: 32734759; PMCID: PMC7361445.
  • Bao W, Liu B, Rong S, Dai SY, Trasande L, Lehmler HJ. Association Between Bisphenol A Exposure and Risk of All-Cause and Cause-Specific Mortality in US Adults. JAMA Netw Open. 2020 Aug 3;3(8):e2011620. doi: 10.1001/jamanetworkopen.2020.11620. PMID: 32804211.
  • Hart A, Goffredo P, Carroll R, Lehmann R, Nau P, Smith J, Ahad S, Bao W, Hassan I. Optimizing Bariatric Surgery outcomes: the impact of preoperative elevated hemoglobin A1c levels on composite perioperative outcome measures. Surg Endosc. 2020 Aug 12. doi: 10.1007/s00464-020-07887-9. Epub ahead of print. PMID: 32789589.
  • Sun Y, Liu B, Rong S, Du Y, Xu G, Snetselaar LG, Wallace RB, Bao W. Food Insecurity Is Associated With Cardiovascular and All-Cause Mortality Among Adults in the United States. J Am Heart Assoc. 2020 Sep 25:e014629. doi: 10.1161/JAHA.119.014629. Epub ahead of print. PMID: 32975173.
  • Qin C, Hu J, Wan Y, Cai M, Wang Z, Peng Z, Liao Y, Li D, Yao P, Liu L, Rong S, Bao W, Xu G, Yang W. Narrative review on potential role of gut microbiota in certain substance addiction. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Sep 6:110093. doi: 10.1016/j.pnpbp.2020.110093. Epub ahead of print. PMID: 32898589.
  • Wu Y, Liu B, Sun Y, Du Y, Santillan MK, Santillan DA, Snetselaar LG, Bao W. Association of Maternal Prepregnancy Diabetes and Gestational Diabetes Mellitus With Congenital Anomalies of the Newborn. Diabetes Care. 2020 Oct 21:dc200261. doi: 10.2337/dc20-0261. Epub ahead of print. PMID: 33087319.
  • Gao R, Liu B, Yang W, Wu Y, Snetselaar LG, Santillan MK, Bao W. Association between maternal pre-pregnancy body mass index and risk of preterm birth in more than 1 million Asian American mothers. J Diabetes. 2020 Oct 19. doi: 10.1111/1753-0407.13124. Epub ahead of print. PMID: 33073932.
  • Yang W, Liu B, Gao R, Snetselaar LG, Strathearn L, Bao W. Association of Anemia with Neurodevelopmental Disorders in A Nationally Representative Sample of US Children. J Pediatr. 2020 Oct 6:S0022-3476(20)31172-0. doi: 10.1016/j.jpeds.2020.09.039. Epub ahead of print. PMID: 33035572.
  • Wu Y, Liu B, Sun Y, Du Y, Santillan MK, Santillan DA, Snetselaar LG, Bao W. Association of Maternal Prepregnancy Diabetes and Gestational Diabetes Mellitus With Congenital Anomalies of the Newborn. Diabetes Care. 2020 Dec;43(12):2983-2990. doi: 10.2337/dc20-0261. Epub 2020 Oct 21. PMID: 33087319.
  • Hu X, Rong S, Wang Q, Sun T, Bao W, Chen L, Liu L. Association between Plasma Uric Acid and Insulin Resistance in Type 2 Diabetes: A Mendelian Randomization Analysis. Diabetes Res Clin Pract. 2020 Nov 20:108542. doi: 10.1016/j.diabres.2020.108542. Epub ahead of print. PMID: 33227361.
  • Sun Y, Liu B, Wallace RB, Bao W. Association of Cannabis Use With All-Cause and Cause-Specific Mortality Among Younger- and Middle-Aged U.S. Adults. Am J Prev Med. 2020 Dec;59(6):873-879. doi: 10.1016/j.amepre.2020.07.010. Epub 2020 Nov 18. PMID: 33220757.
  • Kesse-Guyot E, Rebouillat P, Payrastre L, Allès B, Fezeu LK, Druesne-Pecollo N, Srour B, Bao W, Touvier M, Galan P, Hercberg S, Lairon D, Baudry J. Prospective association between organic food consumption and the risk of type 2 diabetes: findings from the NutriNet-Santé cohort study. Int J Behav Nutr Phys Act. 2020 Nov 9;17(1):136. doi: 10.1186/s12966-020-01038-y. PMID: 33167995; PMCID: PMC7653706.
  • Lehmler HJ, Simonsen D, Liu B, Bao W. Environmental exposure to pyrethroid pesticides in a nationally representative sample of U.S. adults and children: The National Health and Nutrition Examination Survey 2007-2012. Environ Pollut. 2020 Dec;267:115489. doi: 10.1016/j.envpol.2020.115489. Epub 2020 Aug 29. PMID: 33254662; PMCID: PMC7708675.

Melissa Bates, PhD:

  • Bates ML, Gundry RL, Lindsey ML. Using an Investigative Journalism Approach to Design Mechanistic Experiments in Physiology. Physiology (Bethesda). 2020 Jul 1;35(4):218-219. doi: 10.1152/physiol.00006.2020. PubMed PMID: 32490747.
  • Barnard CR, Peters M, Sindler AL, Farrell ET, Baker KR, Palta M, Stauss HM, Dagle JM, Segar J, Pierce GL, Eldridge MW, Bates ML. Increased aortic stiffness and elevated blood pressure in response to exercise in adult survivors of prematurity. Physiol Rep. 2020 Jun;8(12):e14462. doi: 10.14814/phy2.14462. PMID: 32562387; PMCID: PMC7305240.
  • Bates ML, Haack KKV. Everyone must be able to breathe: A plan to support diversity and inclusion in respiratory physiology. Am J Physiol Lung Cell Mol Physiol. 2020 Jun 17. doi: 10.1152/ajplung.00269.2020. Epub ahead of print. PMID: 32551863.
  • Lewandowski AJ, Levy PT, Bates ML, McNamara PJ, Nuyt AM, Goss KN. Impact of the Vulnerable Preterm Heart and Circulation on Adult Cardiovascular Disease Risk. Hypertension. 2020 Oct;76(4):1028-1037. doi: 10.1161/HYPERTENSIONAHA.120.15574. Epub 2020 Aug 17. PMID: 32816574; PMCID: PMC7480939.
  • Bates ML, Levy PT, Nuyt AM, Goss KN, Lewandowski AJ, McNamara PJ. Adult Cardiovascular Health Risk and Cardiovascular Phenotypes of Prematurity. J Pediatr. 2020 Sep 12:S0022-3476(20)31147-1. doi: 10.1016/j.jpeds.2020.09.019. Epub ahead of print. PMID: 32931771.

Christopher Benson, MD: 

  • Khataei T, Harding AMS, Janahmadi M, El-Geneidy M, Agha-Alinejad H, Rajabi H, Snyder PM, Sluka KA, Benson CJ. ASICs are required for immediate exercise-induced muscle pain and are downregulated in sensory neurons by exercise training. J Appl Physiol (1985). 2020 May 28. doi: 10.1152/japplphysiol.00033.2020. [Epub ahead of print] PubMed PMID: 32463731.

Sue Bodine, PhD: 

  • Bodine SC. Adolph Lecture: Skeletal Muscle Atrophy: Multiple Pathways Leading to a Common Outcome. J Appl Physiol (1985). 2020 Jul 9. doi: 10.1152/japplphysiol.00381.2020. Epub ahead of print. PMID: 32644910.
  • van der Zwaard S, de Leeuw AW, Meerhoff LRA, Bodine SC, Knobbe A. Articles with impact: insights into 10 years of research with machine learning. J Appl Physiol (1985). 2020 Aug 13. doi: 10.1152/japplphysiol.00489.2020. Epub ahead of print. PMID: 32790596.
  • Hughes DC, Baehr LM, Driscoll JR, Lynch SA, Waddell DS, Bodine SC. Identification and Characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase. Am J Physiol Cell Physiol. 2020 Aug 12. doi: 10.1152/ajpcell.00253.2020. Epub ahead of print. PMID: 32783651.
  • Hughes DC, Turner DC, Baehr LM, Seaborne RA, Viggars M, Jarvis JC, Gorski PP, Stewart CE, Owens DJ, Bodine SC, Sharples AP. Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism. Am J Physiol Cell Physiol. 2020 Oct 14. doi: 10.1152/ajpcell.00432.2020. Epub ahead of print. PMID: 33052072.
  • de Sousa LGO, Marshall AG, Norman JE, Fuqua JD, Lira VA, Rutledge JC, Bodine SC. THE EFFECTS OF DIET COMPOSITION AND CHRONIC OBESITY ON MUSCLE GROWTH AND FUNCTION. J Appl Physiol (1985). 2020 Nov 19. doi: 10.1152/japplphysiol.00156.2020. Epub ahead of print. PMID: 33211595.

Charles Brenner, PhD:

  • Matasic DS, Yoon JY, McLendon JM, Mehdi H, Schmidt MS, Greiner AM, Quinones P, Morgan GM, Boudreau RL, Irani K, Brenner C, London B. Modulation of the cardiac sodium channel Na(V)1.5 peak and late currents by NAD(+) precursors. J Mol Cell Cardiol. 2020 Mar 21. pii: S0022-2828(20)30073-0. doi: 10.1016/j.yjmcc.2020.01.013. [Epub ahead of print] PubMed PMID: 32209328.
  • Levine DC, Hong H, Weidemann BJ, Ramsey KM, Affinati AH, Schmidt MS, Cedernaes J, Omura C, Braun R, Lee C, Brenner C, Peek CB, Bass J. NAD(+) Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging. Mol Cell. 2020 Jun 4;78(5):835-849.e7. doi: 10.1016/j.molcel.2020.04.010. Epub 2020 May 4. PubMed PMID: 32369735; PubMed Central PMCID: PMC7275919.
  • Gerasimenko M, Cherepanov SM, Furuhara K, Lopatina O, Salmina AB, Shabalova AA, Tsuji C, Yokoyama S, Ishihara K, Brenner C, Higashida H. Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder. Sci Rep. 2020 Jun 22;10(1):10035. doi: 10.1038/s41598-019-57236-7. PMID: 32572044; PMCID: PMC7308284.
  • Nam TS, Park DR, Rah SY, Woo TG, Chung HT, Brenner C, Kim UH. Interleukin-8 drives CD38 to form NAADP from NADP+ and NAAD in the endolysosomes to mobilize Ca2+ and effect cell migration. FASEB J. 2020 Jul 27. doi: 10.1096/fj.202001249R. Epub ahead of print. PMID: 32717131.

Trudy Burns, PhD:

  • Hu T, Gall SL, Widome R, Bazzano LA, Burns TL, Daniels SR, Dwyer T, Ikonen J, Juonala M, Kähönen M, Prineas RJ, Raitakari O, Sinaiko AR, Steinberger J, Urbina EM, Venn A, Viikari J, Woo JG, Jacobs DR Jr. Childhood/Adolescent Smoking and Adult Smoking and Cessation: The International Childhood Cardiovascular Cohort (i3C) Consortium. J Am Heart Assoc. 2020 Apr 7;9(7):e014381. doi: 10.1161/JAHA.119.014381. Epub 2020 Apr 8. PubMed PMID: 32264731.
  • Hu T, Jacobs DR Jr, Sinaiko AR, Bazzano LA, Burns TL, Daniels SR, Dwyer T, Hutri-Kähönen N, Juonala M, Murdy KA, Prineas RJ, Raitakari OT, Urbina EM, Venn A, Woo JG, Steinberger J. Childhood BMI and Fasting Glucose and Insulin Predict Adult Type 2 Diabetes: The International Childhood Cardiovascular Cohort (i3C) Consortium. Diabetes Care. 2020 Sep 1:dc200822. doi: 10.2337/dc20-0822. Epub ahead of print. PMID: 32873588.

Lucas Carr, PhD: 

  • Karvinen KH, Brunet J, Carr LJ. Family history of cancer as a cue to action for physical activity behaviour and beliefs. Psychol Health. 2020 Aug;35(8):933-945. doi: 10.1080/08870446.2019.1693570. Epub 2019 Nov 22. PMID: 31757176.

Darren Casey, PhD:

  • Limberg JK, Casey DP, Trinity J, Nicholson WT, Wray DW, Tschakovsky ME, Green  DJ, Hellsten Y, Fadel PJ, Joyner MJ, Padilla J. Assessment of resistance vessel function in human skeletal muscle: Guidelines for experimental design, Doppler ultrasound, and pharmacology. Am J Physiol Heart Circ Physiol. 2019 Dec 30. doi: 10.1152/ajpheart.00649.2019. [Epub ahead of print] PubMed PMID: 31886718.
  • Hughes WE, Kruse NT, Ueda K, Feider AJ, Hanada S, Bock JM, Casey DP. Dietary nitrate does not acutely enhance skeletal muscle blood flow and vasodilation in the lower limbs of older adults during single-limb exercise. Eur J Appl Physiol. 2020 Jun;120(6):1357-1369. doi: 10.1007/s00421-020-04368-8. Epub 2020 Apr 17. PubMed PMID: 32303829.
  • Bock JM, Iwamoto E, Horak JG, Feider AJ, Hanada S, Casey DP. Aerobic Exercise Offsets Endothelial Dysfunction Induced by Repetitive Consumption of Sugar-Sweetened Beverages in Young Healthy Men. Am J Physiol Regul Integr Comp Physiol. 2020 May 13. doi: 10.1152/ajpregu.00055.2020. [Epub ahead of print] PubMed PMID: 32401628.
  • Iwamoto E, Hanson BE, Bock JM, Casey DP. Intermittent hypoxia enhances shear-mediated dilation of the internal carotid artery in young adults. J Appl Physiol (1985). 2020 Jul 23. doi: 10.1152/japplphysiol.00274.2020. Epub ahead of print. PMID: 32702263.
  • Bock JM, Iwamoto E, Horak JG, Feider AJ, Hanada S, Casey DP. Aerobic exercise offsets endothelial dysfunction induced by repetitive consumption of sugar-sweetened beverages in young healthy men. Am J Physiol Regul Integr Comp Physiol. 2020 Jul 1;319(1):R11-R18. doi: 10.1152/ajpregu.00055.2020. Epub 2020 May 13. PMID: 32401628.
  • Bock JM, Hughes WE, Ueda K, Feider AJ, Hanada S, Kruse NT, Iwamoto E, Casey DP. Greater α1-adrenergic-mediated vasoconstriction in contracting skeletal muscle of patients with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2020 Oct 1;319(4):H797-H807. doi: 10.1152/ajpheart.00532.2020. Epub 2020 Aug 21. PMID: 32822215.
  • Ueda K, Janiczek DM, Casey DP. Arterial Stiffness Predicts General Anesthesia-Induced Vasopressor-Resistant Hypotension in Patients Taking Angiotensin-Converting Enzyme Inhibitors. J Cardiothorac Vasc Anesth. 2020 Aug 22:S1053-0770(20)30834-X. doi: 10.1053/j.jvca.2020.08.040. Epub ahead of print. PMID: 32921603.
  • Hanson BE, Joyner MJ, Casey DP. Sex-Related Differences in Rapid-Onset Vasodilation: Impact of Aging. J Appl Physiol (1985). 2020 Oct 29. doi: 10.1152/japplphysiol.00663.2020. Epub ahead of print. PMID: 33119464.
  • Bock JM, Hanson BE, Asama TF, Feider AJ, Hanada S, Aldrich AW, Dyken ME, Casey DP. Acute inorganic nitrate supplementation and the hypoxic ventilatory response in patients with obstructive sleep apnea. J Appl Physiol (1985). 2020 Nov 19. doi: 10.1152/japplphysiol.00696.2020. Epub ahead of print. PMID: 33211592.
  • Bock JM, Hughes WE, Ueda K, Feider AJ, Hanada S, Kruse NT, Iwamoto E, Casey DP. Greater α1-adrenergic-mediated vasoconstriction in contracting skeletal muscle of patients with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2020 Oct 1;319(4):H797-H807. doi: 10.1152/ajpheart.00532.2020. Epub 2020 Aug 21. PMID: 32822215.
  • Iwamoto E, Sakamoto R, Tsuchida W, Yamazaki K, Kamoda T, Neki T, Katayose M, Casey DP. Effects of menstrual cycle and menopause on internal carotid artery shear-mediated dilation in women. Am J Physiol Heart Circ Physiol. 2020 Dec 11. doi: 10.1152/ajpheart.00810.2020. Epub ahead of print. PMID: 33306444.

Mark Chapleau, PhD: 

  • Barboi A, Gibbons CH, Axelrod F, Benarroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR; American Autonomic Society. Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society. Auton Neurosci. 2020 Jan;223:102550. doi: 10.1016/j.autneu.2019.05.002. PubMed PMID: 31928708.

Bhagirath Chaurasia, PhD: 

  • Chaurasia B, Talbot CL, Summers SA. Adipocyte Ceramides-The Nexus of Inflammation and Metabolic Disease. Front Immunol. 2020 Sep 23;11:576347. doi: 10.3389/fimmu.2020.576347. PMID: 33072120; PMCID: PMC7538607.
  • Chaurasia B, Summers SA. Ceramides in Metabolism: Key Lipotoxic Players. Annu Rev Physiol. 2020 Nov 6. doi: 10.1146/annurev-physiol-031620-093815. Epub ahead of print. PMID: 33158378.
  • Chaurasia B, Ying L, Talbot CL, Maschek JA, Cox J, Schuchman EH, Hirabayashi Y, Holland WL, Summers SA. Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes. Mol Metab. 2020 Dec 19:101145. doi: 10.1016/j.molmet.2020.101145. Epub ahead of print. PMID: 33352310.

Huxing Cui, PhD: 

  • Davis KC, Saito K, Rodeghiero SR, Toth BA, Lutter M, Cui H. Behavioral Alterations in Mice Carrying Homozygous HDAC4A778T Missense Mutation Associated With Eating Disorder. Front Neurosci. 2020 Feb 21;14:139. doi: 10.3389/fnins.2020.00139. PMID: 32153359; PMCID: PMC7046559.
  • Deng G, Morselli LL, Wagner VA, Balapattabi K, Sapouckey SA, Knudtson KL, Rahmouni K, Cui H, Sigmund CD, Kwitek AE, Grobe JL. Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity. Hypertension. 2020 Jun 8:HYPERTENSIONAHA12015137. doi: 10.1161/HYPERTENSIONAHA.120.15137. [Epub ahead of print] PubMed PMID: 32507042.
  • Yamanashi T, Malicoat JR, Steffen KT, Zarei K, Li R, Purnell BS, Najafi A, Saito K, Singh U, Toth BA, Lee S, Dailey ME, Cui H, Kaneko K, Cho HR, Iwata M, Buchanan GF, Shinozaki G. Bispectral EEG (BSEEG) quantifying neuro-inflammation in mice induced by systemic inflammation: A potential mouse model of delirium. J Psychiatr Res. 2020 Dec 15;133:205-211. doi: 10.1016/j.jpsychires.2020.12.036. Epub ahead of print. PMID: 33360427.

Brandon Davies, PhD: 

  • Qiao L, Shetty SK, Spitler KM, Wattez JS, Davies BSJ, Shao J. Obesity Reduces  Maternal Blood Triglyceride Concentrations by Reducing Angiopoietin-like Protein  4 Expression in Mice. Diabetes. 2020 Feb 12. pii: db191181. doi: 10.2337/db19-1181. [Epub ahead of print] PubMed PMID:
  • Spitler KM, Davies BSJ. Aging and plasma triglyceride metabolism. J Lipid Res. 2020 Aug;61(8):1161-1167. doi: 10.1194/jlr.R120000922. Epub 2020 Jun 25. PMID: 32586846.

Sanjana Dayal, PhD: 

  • Gu SX, Sonkar VK, Katare PB, Kumar R, Kruger WD, Arning E, Bottiglieri T, Lentz SR, Dayal S. Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia. J Am Heart Assoc. 2020 Feb 18;9(4):e013368. doi: 10.1161/JAHA.119.013368. Epub 2020 Feb 13. PMID: 32067580.
  • Chu Y, Lan RS, Huang R, Feng H, Kumar R, Dayal S, Chan KS, Dai DF. Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice. Aging Cell. 2020 May 13. doi: 10.1111/acel.13154. [Epub ahead of print] PubMed PMID: 32400101.

Ayotunde Dokun, MD, PhD: 

  • Alleboina S, Wong T, Singh MV, Dokun AO. Inhibition of protein kinase C beta phosphorylation activates nuclear factor-kappa B and improves postischemic recovery in type 1 diabetes. Exp Biol Med (Maywood). 2020 Apr 23:1535370220920832. doi: 10.1177/1535370220920832. [Epub ahead of print] PubMed PMID: 32326759.
  • Jain N, Agarwal MA, Jalal D, Dokun AO. Individuals with Peripheral Artery Disease (PAD) and Type 1 Diabetes Are More Likely to Undergo Limb Amputation than Those with PAD and Type 2 Diabetes. J Clin Med. 2020 Aug 31;9(9):E2809. doi: 10.3390/jcm9092809. PMID: 32878057.

John Engelhardt, PhD:

  • Choi SH, Reeves RE, Romano Ibarra GS, Lynch TJ, Shahin WS, Feng Z, Gasser GN, Winter MC, Evans TIA, Liu X, Luo M, Zhang Y, Stoltz DA, Devor EJ, Yan Z, Engelhardt JF. Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b. Genes (Basel). 2020 Oct 6;11(10):E1169. doi: 10.3390/genes11101169. PMID: 33036232.

Frank Faraci, PhD: 

  • Faraci FM. Neurovascular coupling: Sending this signal here, hope you pick it up loud and clear. J Physiol. 2020 Sep 1. doi: 10.1113/JP280630. Epub ahead of print. PMID: 32869875.

Edward Filardo, PhD:

  • Rouhimoghadam M, Lu AS, Salem AK, Filardo EJ. Therapeutic Perspectives on the Modulation of G-Protein Coupled Estrogen Receptor, GPER, Function. Front Endocrinol (Lausanne). 2020 Nov 23;11:591217. doi: 10.3389/fendo.2020.591217. PMID: 33329395; PMCID: PMC7719807.

James Folk, MD: 

  • Li AS, Velez G, Darbro B, Toral MA, Yang J, Tsang SH, Ferguson PJ, Folk JC, Bassuk AG, Mahajan VB. Whole-Exome Sequencing of Patients with Posterior Segment Uveitis. Am J Ophthalmol. 2020 Jul 21:S0002-9394(20)30378-0. doi: 10.1016/j.ajo.2020.07.021. Epub ahead of print. PMID: 32707200.

Bernd Fritzsch, PhD: 

  • Erives A, Fritzsch B. A Screen for Gene Paralogies Delineating Evolutionary Branching Order of Early Metazoa. G3 (Bethesda). 2019 Dec 26. pii: g3.400951.2019. doi: 10.1534/g3.119.400951. [Epub ahead of print] PubMed PMID: 31879283.
  • Nichols DH, Bouma JE, Kopecky BJ, Jahan I, Beisel KW, He DZZ, Liu H, Fritzsch  B. Interaction with ectopic cochlear crista sensory epithelium disrupts basal cochlear sensory epithelium development in Lmx1a mutant mice. Cell Tissue Res. 2020 Jan 13. doi: 10.1007/s00441-019-03163-y. [Epub ahead of print] PubMed PMID:  31932950.
  • Herranen A, Ikäheimo K, Lankinen T, Pakarinen E, Fritzsch B, Saarma M, LindahlM, Pirvola U. Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss. Cell Death Dis. 2020 Feb 6;11(2):100.doi: 10.1038/s41419-020-2286-6. PubMed PMID: 32029702; PubMed Central PMCID: PMC7005028.
  • Yamoah EN, Li M, Shah A, Elliott KL, Cheah K, Xu PX, Phillips S, Young SM Jr,  Eberl DF, Fritzsch B. Using Sox2 to alleviate the hallmarks of age-related hearing loss. Ageing Res Rev. 2020 May;59:101042. doi: 10.1016/j.arr.2020.101042. Epub 2020 Mar 12. Review. PubMed PMID: 32173536.
  • Kersigo J, Gu L, Xu L, Pan N, Vijayakuma S, Jones T, Shibata SB, Fritzsch B, Hansen MR. Effects of Neurod1 Expression on Mouse and Human Schwannoma Cells. Laryngoscope. 2020 May 21. doi: 10.1002/lary.28671. [Epub ahead of print] PubMed PMID: 32438526.
  • Filova I, Dvorakova M, Bohuslavova R, Pavlinek A, Elliott KL, Vochyanova S, Fritzsch B, Pavlinkova G. Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers. Mol Neurobiol. 2020 Dec;57(12):5307-5323. doi: 10.1007/s12035-020-02092-0. Epub 2020 Sep 3. PMID: 32880858; PMCID: PMC7547283.
  • Chizhikov VV, Iskusnykh IY, Fattakhov N, Fritzsch B. Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System. Neuroscience. 2021 Jan 1;452:247-264. doi: 10.1016/j.neuroscience.2020.11.013. Epub 2020 Nov 24. PMID: 33246067.

Katherine Gibson-Corley, PhD: 

  • Kluz PN, Kolb R, Xie Q, Borcherding N, Liu Q, Luo Y, Kim MC, Wang L, Zhang Y,  Li W, Stipp C, Gibson-Corley KN, Zhao C, Qi HH, Bellizzi A, Tao AW, Sugg S, Weigel RJ, Zhou D, Shen X, Zhang W. Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. Oncogene. 2020 Feb 10. doi: 10.1038/s41388-020-1203-x. [Epub ahead of print] PubMed PMID: 32042113.
  • Holland MT, Seaman SC, Woodroffe RW, Fredericks DC, Kovach CK, Gibson-Corley KN, Gillies GT, Howard MA 3rd. In Vivo Testing of a Prototype Intradural Spinal Cord Stimulator in a Porcine Model. World Neurosurg. 2020 Feb 26. pii: S1878-8750(20)30375-2. doi: 10.1016/j.wneu.2020.02.100. [Epub ahead of print] PubMed PMID: 32112934.
  • Sapouckey SA, Morselli LL, Deng G, Patil C, Balapattabi K, Oliveira V, Claflin KE, Gomez J, Pearson NA, Potthoff MJ, Gibson-Corley KN, Sigmund CD, Grobe JL. Exploration of cardiometabolic and developmental significance of angiotensinogen  expression by cells expressing the leptin receptor or Agouti-related peptide. Am  J Physiol Regul Integr Comp Physiol. 2020 Mar 18. doi: 10.1152/ajpregu.00297.2019. [Epub ahead of print] PubMed PMID: 32186897[EDA1].
  • Hamity MV, White SR, Blum C, Gibson-Corley KN, Hammond DL. Nicotinamide riboside relieves paclitaxel-induced peripheral neuropathy and enhances suppression of tumor growth in tumor-bearing rats. Pain. 2020 May 15. doi: 10.1097/j.pain.0000000000001924. [Epub ahead of print] PubMed PMID: 32433266.
  • Webster JD, Solon M, Gibson-Corley KN. Validating Immunohistochemistry Assay Specificity in Investigative Studies: Considerations for a Weight of Evidence Approach. Vet Pathol. 2020 Sep 25:300985820960132. doi: 10.1177/0300985820960132. Epub ahead of print. PMID: 32975488.

Mark Greiner, MD:

  • Goldstein AS, Janson BJ, Skeie JM, Ling JJ, Greiner MA. The Effects of Diabetes Mellitus on the Corneal Endothelium: A Review. Surv Ophthalmol. 2020 Jan 8. pii: S0039-6257(20)30005-9. doi: 10.1016/j.survophthal.2019.12.009. [Epub ahead of print] Review. PubMed PMID: 31926185.
  • Skeie JM, Aldrich BT, Nishimura DY, Schmidt GA, Zimmerman MB, Ling JJ, Naguib YW, Salem AK, Greiner MA. Ubiquinol Supplementation of Donor Tissue Enhances Corneal Endothelial Cell Mitochondrial Respiration. Cornea. 2020 Jun 15. doi: 10.1097/ICO.0000000000002408. [Epub ahead of print] PubMed PMID: 32558735.
  • Ling JJ, Kyrillos R, Burckart KA, Aldrich BT, Skeie JM, Schmidt GA, Conwell C, Ramirez T, Reed CR, Zimmerman MB, Greiner MA, Li JY. Optimizing Visualization of Descemet Membrane Endothelial Keratoplasty Tissue: Assessing the Impact of Trypan Blue Exposure on Stain Duration and Corneal Endothelial Cell Function. Cornea. 2020 Jul 27. doi: 10.1097/ICO.0000000000002440. Epub ahead of print. PMID: 32732698.
  • Schlötzer-Schrehardt U, Zenkel M, Strunz M, Gießl A, Schondorf H, da Silva H, Schmidt GA, Greiner MA, Okumura N, Koizumi N, Kinoshita S, Tourtas T, Kruse FE. Potential functional restoration of corneal endothelial cells in Fuchs endothelial corneal dystrophy by ROCK inhibitor (ripasudil). Am J Ophthalmol. 2020 Dec 11:S0002-9394(20)30664-4. doi: 10.1016/j.ajo.2020.12.006. Epub ahead of print. PMID: 33316261.

Chad Grueter, PhD:

  • Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE. Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. J Am Heart Assoc. 2020 Apr 7;9(7):e014366. doi: 10.1161/JAHA.119.014366. Epub 2020 Apr 4. PubMed PMID: 32248761.

Isabella Grumbach, MD, PhD: 

  • Grumbach IM. Cardio-Oncology at the Beginning of a New Decade. J Am Heart Assoc. 2020 Jan 21;9(2):e015890. doi: 10.1161/JAHA.120.015890. Epub 2020 Jan 21. PubMed PMID: 31959029.
  • Gupta AK, Jneid H, Addison D, Ardehali H, Boehme AK, Borgaonkar S, Boulestreau R, Clerkin K, Delarche N, DeVon HA, Grumbach IM, Gutierrez J, Jones DA, Kapil V, Maniero C, Mentias A, Miller PS, May Ng S, Parekh JD, Sanchez RH, Teodor Sawicki K, S J M Te Riele A, Ann Remme C, London B. Current perspectives on Coronavirus 2019 (COVID-19) and cardiovascular disease: A white paper by the JAHA editors. J Am Heart Assoc. 2020 Apr 29:e017013. doi: 10.1161/JAHA.120.017013. [Epub ahead of print] PubMed PMID: 32347144.

Charles Harata, MD, PhD: 

  • Kawano H, Mitchell SB, Koh JY, Goodman KM, Harata NC. Calcium-induced calcium  release in noradrenergic neurons of the locus coeruleus. Brain Res. 2019 Dec 27;1729:146627. doi: 10.1016/j.brainres.2019.146627. [Epub ahead of print] PubMed PMID: 31883849.
  • Oyabu K, Takeda K, Kawano H, Kubota K, Watanabe T, Harata NC, Katsurabayashi S, Iwasaki K. Presynaptically silent synapses are modulated by the density of surrounding astrocytes. J Pharmacol Sci. 2020 Jul 24:S1347-8613(20)30074-8. doi: 10.1016/j.jphs.2020.07.009. Epub ahead of print. PMID: 32736867.
  • White S, Kawano H, Harata NC, Roller RJ. Herpes Simplex Virus Organizes Cytoplasmic Membranes to Form a Viral Assembly Center in Neuronal Cells. J Virol. 2020 Jul 22:JVI.00900-20. doi: 10.1128/JVI.00900-20. Epub ahead of print. PMID: 32699089.

Yumi Imai, MD: 

  • Imai Y, Cousins RS, Liu S, Phelps BM, Promes JA. Connecting pancreatic islet lipid metabolism with insulin secretion and the development of type 2 diabetes. Ann N Y Acad Sci. 2020 Feb;1461(1):53-72. doi: 10.1111/nyas.14037. Epub 2019 Apr 2. PMID: 30937918.
  • Liu S, Promes JA, Harata M, Mishra A, Stephens SB, Taylor EB, Burand AJ Jr, Sivitz WI, Fink BD, Ankrum JA, Imai Y. Adipose Triglyceride Lipase is a Key Lipase for the Mobilization of Lipid Droplets in Human Beta Cells and Critical for the Maintenance of Syntaxin1a Level in Beta Cells. Diabetes. 2020 Mar 31. pii: db190951. doi: 10.2337/db09-0951. [Epub ahead of print] PubMed PMID: 32234723.
  • Cho J, Hiramoto M, Masaike Y, Sakamoto S, Imai Y, Imai Y, Handa H, Imai T. UGGT1 retains proinsulin in the endoplasmic reticulum in an arginine dependent manner. Biochem Biophys Res Commun. 2020 May 15. pii: S0006-291X(20)30903-7. doi: 10.1016/j.bbrc.2020.04.158. [Epub ahead of print] PubMed PMID: 32423812.
  • Cho J, Horikawa Y, Enya M, Takeda J, Imai Y, Imai Y, Handa H, Imai T. L-Arginine prevents cereblon-mediated ubiquitination of glucokinase and stimulates glucose-6-phosphate production in pancreatic β-cells. Commun Biol. 2020 Sep 8;3(1):497. doi: 10.1038/s42003-020-01226-3. PMID: 32901087; PMCID: PMC7479149.

Kathleen Janz, PhD: 

  • Metcalf KM, Letuchy EM, Levy SM, Janz KF. An 8-Year Longitudinal Analysis of Physical Activity and Bone Strength From Adolescence to Emerging Adulthood: The Iowa Bone Development Study. Pediatr Exerc Sci. 2020 Jan 2:1-7. doi: 10.1123/pes.2019-0090. [Epub ahead of print] PubMed PMID: 31896075
  • Rowlands AV, Edwardson CL, Dawkins NP, Maylor BD, Metcalf KM, Janz KF. Physical Activity for Bone Health: How Much and/or How Hard? Med Sci Sports Exerc. 2020 May 21. doi: 10.1249/MSS.0000000000002380. [Epub ahead of print] PubMed PMID: 32453172.
  • van Ekris E, Wijndaele K, Altenburg TM, Atkin AJ, Twisk J, Andersen LB, Janz KF, Froberg K, Northstone K, Page AS, Sardinha LB, van Sluijs EMF, Chinapaw M; International Children’s Accelerometry Database (ICAD) Collaborators. Tracking of total sedentary time and sedentary patterns in youth: a pooled analysis using the International Children's Accelerometry Database (ICAD). Int J Behav Nutr Phys Act. 2020 May 18;17(1):65. doi: 10.1186/s12966-020-00960-5. PubMed PMID: 32423404; PubMed Central PMCID: PMC7236462.
  • Pashkova A, Hartman JM, Letuchy EM, Janz KF. Interscholastic Athletics and Bone Strength: The Iowa Bone Development Study. J Strength Cond Res. 2020 May 25. doi: 10.1519/JSC.0000000000003646. [Epub ahead of print] PubMed PMID: 32459739.
  • Bernhardsen GP, Stensrud T, Hansen BH, Steene-Johannesen J, Kolle E, Nystad W, Anderssen SA, Hallal PC, Janz KF, Kriemler S, Andersen LB, Northstone K, Resaland GK, Sardinha LB, van Sluijs EMF, Ried-Larsen M, Ekelund U; International Children’s Accelerometry Database (ICAD) Collaborators. Birth weight, cardiometabolic risk factors and effect modification of physical activity in children and adolescents: pooled data from 12 international studies. Int J Obes (Lond). 2020 Jun 3. doi: 10.1038/s41366-020-0612-9. [Epub ahead of print] PubMed PMID: 32494037.

Randy Kardon, MD, PhD: 

  • Ledolter J, Kardon RH. Focus on Data: Statistical Design of Experiments and Sample Size Selection Using Power Analysis. Invest Ophthalmol Vis Sci. 2020 Jul 1;61(8):11. doi: 10.1167/iovs.61.8.11. PMID: 32645134.
  • Gramlich OW, Brown AJ, Godwin CR, Chimenti MS, Boland LK, Ankrum JA, Kardon RH. Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis. Transl Vis Sci Technol. 2020 Jul 10;9(8):16. doi: 10.1167/tvst.9.8.16. PMID: 32855863; PMCID: PMC7422913.
  • Sibony PA, Kupersmith MJ, Kardon RH. Optical Coherence Tomography Neuro-Toolbox for the Diagnosis and Management of Papilledema, Optic Disc Edema, and Pseudopapilledema. J Neuroophthalmol. 2020 Sep 4. doi: 10.1097/WNO.0000000000001078. Epub ahead of print. PMID: 32909979.
  • Harper MM, Boese EA, Kardon RH, Ledolter J, Kuehn MH. High Correlation between Glaucoma Treatment with Topical Prostaglandin Analogs and BDNF Immunoreactivity in Human Retina. Curr Eye Res. 2020 Sep 27:1-7. doi: 10.1080/02713683.2020.1822417. Epub ahead of print. PMID: 32985274.

Modar Kassan, PhD: 

  • Ait-Aissa K, Nguyen QM, Gabani M, Kassan A, Kumar S, Choi SK, Gonzalez AA, Khataei T, Sahyoun AM, Chen C, Kassan M. MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy. Cardiovasc Diabetol. 2020 Sep 9;19(1):136. doi: 10.1186/s12933-020-01107-3. PMID: 32907629; PMCID: PMC7488343.
  • Rivera P, Miranda C, Roldán N, Guerrero A, Olave J, Cárdenas P, Nguyen QM, Kassan M, Gonzalez AA. Augmented transcripts of kidney injury markers and renin angiotensin system in urine samples of overweight young adults. Sci Rep. 2020 Dec 3;10(1):21154. doi: 10.1038/s41598-020-78382-3. PMID: 33273645; PMCID: PMC7713175.

Robert Kerns, PhD:

  • Aguirre AL, Chheda PR, Lentz SRC, Held HA, Groves NP, Hiasa H, Kerns RJ. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28(10):115439. doi: 10.1016/j.bmc.2020.115439. Epub 2020 Mar 13. PubMed PMID: 32234278.

Aloysius Klingelhutz, PhD: 

  • Gourronc FA, Markan KR, Kulhankova K, Zhu Z, Sheehy R, Quelle DE, Zingman LV, Kurago ZB, Ankrum JA, Klingelhutz AJ. Pdgfrα-Cre mediated knockout of the aryl hydrocarbon receptor protects mice from high-fat diet induced obesity and hepatic steatosis. PLoS One. 2020 Jul 30;15(7):e0236741. doi: 10.1371/journal.pone.0236741. PMID: 32730300; PMCID: PMC7392206.
  • Schlievert PM, Gourronc FA, Leung DYM, Klingelhutz AJ. Human Keratinocyte Response to Superantigens. mSphere. 2020 Oct 7;5(5):e00803-20. doi: 10.1128/mSphere.00803-20. PMID: 33028686.

Anne Kwitek, PhD:

  • Berillo O, Ouerd S, Idris-Khodja N, Rehman A, Richer C, Sinnett D, Kwitek AE, Paradis P, Schiffrin EL. Chromosome 2 Fragment Substitutions in Dahl Salt-Sensitive Rats and RNA Sequencing Identified Enpep and Hs2st1 as Vascular Inflammatory Modulators. Hypertension. 2020 Nov 9:HYPERTENSIONAHA12015690. doi: 10.1161/HYPERTENSIONAHA.120.15690. Epub ahead of print. PMID: 33161775.

Ashutosh Mangalam, PhD:

  •  Mangalam AK, Ochoa-Repáraz J. Editorial: The Role of the Gut Microbiota in Health and Inflammatory Diseases. Front Immunol. 2020 Sep 17;11:565305. doi: 10.3389/fimmu.2020.565305. PMID: 33042145; PMCID: PMC7527406.
  • Marietta E, Mangalam AK, Taneja V, Murray JA. Intestinal Dysbiosis in, and Enteral Bacterial Therapies for, Systemic Autoimmune Diseases. Front Immunol. 2020 Oct 28;11:573079. doi: 10.3389/fimmu.2020.573079. PMID: 33193357; PMCID: PMC7655733.
  • Jensen IJ, Jensen SN, Sjaastad FV, Gibson-Corley KN, Dileepan T, Griffith TS, Mangalam AK, Badovinac VP. Sepsis impedes EAE disease development and diminishes autoantigen-specific naïve CD4 T cells. Elife. 2020 Nov 16;9:e55800. doi: 10.7554/eLife.55800. Epub ahead of print. PMID: 33191915.

Mohamad Mokadem, MD:

  • Ye Y, Abu El Haija M, Morgan DA, Guo D, Song Y, Frank A, Tian L, Riedl RA, Burnett CML, Gao Z, Zhu Z, Shahi SK, Zarei K, Couvelard A, Poté N, Ribeiro-Parenti L, Bado A, Noureddine L, Bellizzi A, Kievit P, Mangalam AK, Zingman LV, Le Gall M, Grobe JL, Kaplan LM, Clegg D, Rahmouni K, Mokadem M. Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass. Cell Rep. 2020 Oct 27;33(4):108270. doi: 10.1016/j.celrep.2020.108270. PMID: 33113371; PMCID: PMC7660289.

Andrew Norris, MD, PhD: 

  • Rickels MR, Norris AW, Hull RL. A tale of two pancreases: exocrine pathology and endocrine dysfunction. Diabetologia. 2020 Oct;63(10):2030-2039. doi: 10.1007/s00125-020-05210-8. Epub 2020 Sep 7. PMID: 32894313.

Brian O'Neill, MD, PhD: 

  • Skurski J, Penniman CM, Geesala R, Dixit G, Pulipati P, Bhardwaj G, Meyerholz  DK, Issuree PD, O'Neill BT, Maretzky T. Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation. Metabolism. 2020 Mar 2:154194. doi: 10.1016/j.metabol.2020.154194.  [Epub ahead of print] PubMed PMID: 32135161.

Gary Pierce, PhD:

  • Holwerda SW, Holland MT, Green AL, Pearson ACS, Pierce GL. Dissociation between reduced pain and arterial blood pressure following epidural spinal cord stimulation in patients with chronic pain: A retrospective study. Clin Auton Res. 2020 Apr 22. doi: 10.1007/s10286-020-00690-5. [Epub ahead of print] PubMed PMID: 32323062.
  • Hoth KF, Moreau KL, Weinberger HD, Holm KE, Meschede K, Crapo JD, Make BJ, Moser DJ, Kozora E, Bowler RP, Pierce GL, Ten Eyck P, Wamboldt FS. Carotid Artery Stiffness is Associated With Cognitive Performance in Former Smokers With and Without Chronic Obstructive Pulmonary Disease. J Am Heart Assoc. 2020 May 5;9(9):e014862. doi: 10.1161/JAHA.119.014862. Epub 2020 Apr 26. PubMed PMID: 32338117.
  • Holwerda SW, Kardon RH, Hashimoto R, Full JM, Nellis JK, DuBose LE, Fiedorowicz JG, Pierce GL. Aortic stiffness is associated with changes in retinal arteriole flow pulsatility mediated by local vasodilation in healthy young/middle-age adults. J Appl Physiol (1985). 2020 May 21. doi: 10.1152/japplphysiol.00252.2020. [Epub ahead of print] PubMed PMID: 32437246.
  • Nuckols VR, Holwerda SW, Luehrs RE, DuBose LE, Stroud AK, Brandt D, Betz AM, Fiedorowicz JG, Scroggins SM, Santillan DA, Grobe JL, Sigmund CD, Santillan MK, Pierce GL. Beat-to-Beat Blood Pressure Variability in the First Trimester Is Associated With the Development of Preeclampsia in a Prospective Cohort: Relation With Aortic Stiffness. Hypertension. 2020 Sep 21:HYPERTENSIONAHA12015019. doi: 10.1161/HYPERTENSIONAHA.120.15019. Epub ahead of print. PMID: 32951467.
  • Holwerda SW, Carter JR, Yang H, Wang J, Pierce GL, Fadel PJ. Standardizing methodology for assessing spontaneous baroreflex control of muscle sympathetic nerve activity in humans. Am J Physiol Heart Circ Physiol. 2020 Dec 4. doi: 10.1152/ajpheart.00704.2020. Epub ahead of print. PMID: 33275522.

Catherina Pinnaro, PhD:

  • O'Malley G, Ebekozien O, Desimone M, Pinnaro CT, Roberts A, Polsky S, Noor N, Aleppo G, Basina M, Tansey M, Steenkamp D, Vendrame F, Lorincz I, Mathias P, Agarwal S, Golden L, Hirsh IB, Levy CJ. COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multi-Center Surveillance Study. J Clin Endocrinol Metab. 2020 Nov 9:dgaa825. doi: 10.1210/clinem/dgaa825. Epub ahead of print. PMID: 33165563.

Robert Piper, PhD: 

  • MacDonald C, Shields SB, Williams CA, Winistorfer S, Piper RC. A Cycle of Ubiquitination Regulates Adaptor Function of the Nedd4-Family Ubiquitin Ligase Rsp5. Curr Biol. 2020 Jan 3. pii: S0960-9822(19)31588-X. doi: 10.1016/j.cub.2019.11.086. [Epub ahead of print] PubMed PMID: 31956026.
  • Piper RC. ESCRTs cut some slack. Nat Cell Biol. 2020 Aug;22(8):915-916. doi: 10.1038/s41556-020-0557-1. PMID: 32753668.

Philip Polgreen, MD: 

  • Miller AC, Comellas AP, Hornick DB, Stoltz DA, Cavanaugh JE, Gerke AK, Welsh MJ, Zabner J, Polgreen PM. Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions. Proc Natl Acad Sci U S A. 2019 Dec 27. pii: 201914912. doi: 10.1073/pnas.1914912117. [Epub ahead of print] PubMed PMID: 31882447.
  • Stapleton EM, Simmering JE, Manges RB, Chipara O, Stone EA, Zabner J, Peters TM, Herman T, Polgreen PM, Comellas AP. Continuous in-home PM(2.5) concentrations of smokers with and without a history of respiratory exacerbations in Iowa, during and after an air purifier intervention. J Expo Sci Environ Epidemiol. 2020 May 28. doi: 10.1038/s41370-020-0235-1. [Epub ahead of print] PubMed PMID: 32461549.
  • Simmering JE, Polgreen LA, Polgreen PM, Teske RE, Comellas AP, Carter BL. The Cardiovascular Effects of Treatment with Hydroxychloroquine and Azithromycin. Pharmacotherapy. 2020 Jul 16:10.1002/phar.2445. doi: 10.1002/phar.2445. Epub ahead of print. PMID: 32677113; PMCID: PMC7404845.
  • Winthrop KL, Brunton AE, Beekmann S, Polgreen P, Baddley J, Saag KG, Calabrese C, Calabrese L, Robinson PC, Wallace ZS, Curtis JR; COVID-19 Study Team. SARS CoV-2 infection among patients using immunomodulatory therapies. Ann Rheum Dis. 2020 Aug 5:annrheumdis-2020-218580. doi: 10.1136/annrheumdis-2020-218580. Epub ahead of print. PMID: 32759259.

Matthew Potthoff, PhD:

  • Jensen-Cody SO, Flippo KH, Claflin KE, Yavuz Y, Sapouckey SA, Walters GC, Usachev YM, Atasoy D, Gillum MP, Potthoff MJ. FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake. Cell Metab. 2020 Jun 30:S1550-4131(20)30309-0. doi: 10.1016/j.cmet.2020.06.008. Epub ahead of print. PMID: 32640184.
  • Nayak MK, Ghatge M, Flora GD, Dhanesha N, Jain M, Markan KR, Potthoff MJ, Lentz SR, Chauhan AK. Metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis. Blood. 2020 Oct 7:blood.2020007140. doi: 10.1182/blood.2020007140. Epub ahead of print. PMID: 33027814.
  • Flippo KH, Jensen-Cody SO, Claflin KE, Potthoff MJ. FGF21 signaling in glutamatergic neurons is required for weight loss associated with dietary protein dilution. Sci Rep. 2020 Nov 11;10(1):19521. doi: 10.1038/s41598-020-76593-2. PMID: 33177640; PMCID: PMC7658965.
  • Jensen-Cody SO, Potthoff MJ. Hepatokines and metabolism: Deciphering communication from the liver. Mol Metab. 2020 Dec 4:101138. doi: 10.1016/j.molmet.2020.101138. Epub ahead of print. PMID: 33285302.
  • Markan KR, Boland LK, King-McAlpin AQ, Claflin KE, Leaman MP, Kemerling MK, Stonewall MM, Amendt BA, Ankrum JA, Potthoff MJ. Corrigendum to "Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo" [Molecular Metabolism 36 (2020) 100965]. Mol Metab. 2020 Dec 24:101148. doi: 10.1016/j.molmet.2020.101148. Epub ahead of print. Erratum for: Mol Metab. 2020 Jun;36:100965. PMID: 33358927.

Kamal Rahmouni, PhD:

  • Guo DF, Reho JJ, Morgan DA, Rahmouni K. Cardiovascular Regulation by the Neuronal BBSome. Hypertension. 2020 Mar 9:HYPERTENSIONAHA11914373. doi: 10.1161/HYPERTENSIONAHA.119.14373. [Epub ahead of print] PubMed PMID: 32148123.
  • Wu J, Agbor LN, Fang S, Mukohda M, Nair AR, Nakagawa P, Sharma A, Morgan DA, Grobe JL, Rahmouni K, Weiss RM, McCormick JA, Sigmund CD. Failure to Vasodilate in Response to Salt Loading Blunts Renal Blood Flow and Causes Salt-Sensitive Hypertension. Cardiovasc Res. 2020 May 19. pii: cvaa147. doi: 10.1093/cvr/cvaa147. [Epub ahead of print] PubMed PMID: 32428209.
  • Nakagawa P, Nair AR, Agbor LN, Gomez J, Wu J, Zhang SY, Lu KT, Morgan DA, Rahmouni K, Grobe JL, Sigmund CD. Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-Induced Organ Damage. Hypertension. 2020 Jun 8:HYPERTENSIONAHA12014972. doi: 10.1161/HYPERTENSIONAHA.120.14972. [Epub ahead of print] PubMed PMID: 32507043.
  • Wang P, Loh KH, Wu M, Morgan DA, Schneeberger M, Yu X, Chi J, Kosse C, Kim D, Rahmouni K, Cohen P, Friedman J. A leptin-BDNF pathway regulating sympathetic innervation of adipose tissue. Nature. 2020 Jul;583(7818):839-844. doi: 10.1038/s41586-020-2527-y. Epub 2020 Jul 22. PMID: 32699414.
  • Jiang J, Morgan DA, Cui H, Rahmouni K. Activation of Hypothalamic AgRP and POMC Neurons Evokes Disparate Sympathetic and Cardiovascular Responses. Am J Physiol Heart Circ Physiol. 2020 Sep 18. doi: 10.1152/ajpheart.00411.2020. Epub ahead of print. PMID: 32946297.
  • Seoane-Collazo P, Diéguez C, Nogueiras R, Rahmouni K, Fernández-Real JM, López M. Nicotine' actions on energy balance: Friend or foe? Pharmacol Ther. 2020 Sep 26:107693. doi: 10.1016/j.pharmthera.2020.107693. Epub ahead of print. PMID: 32987056.
  • de Souza Cordeiro LM, Elsheikh A, Devisetty N, Morgan DA, Ebert SN, Rahmouni K, Chhabra KH. Hypothalamic MC4R regulates glucose homeostasis through adrenaline-mediated control of glucose reabsorption via renal GLUT2 in mice. Diabetologia. 2020 Oct 14. doi: 10.1007/s00125-020-05289-z. Epub ahead of print. PMID: 33052459.
  • Jiang J, Morgan DA, Cui H, Rahmouni K. Activation of hypothalamic AgRP and POMC neurons evokes disparate sympathetic and cardiovascular responses. Am J Physiol Heart Circ Physiol. 2020 Nov 1;319(5):H1069-H1077. doi: 10.1152/ajpheart.00411.2020. Epub 2020 Sep 18. PMID: 32946297

Jennifer Robinson, MD:

  • Nanna MG, Navar AM, Wang TY, Li S, Virani SS, Li Z, Robinson JG, Roger VL, Wilson PWF, Goldberg AC, Koren A, Louie MJ, Peterson ED. Practice-level variation in statin use and low-density lipoprotein cholesterol control in the United States: Results from the Patient and Provider Assessment of Lipid Management (PALM) registry. Am Heart J. 2019 Aug;214:113-124. doi:10.1016/j.ahj.2019.05.009. Epub 2019 May 22. PubMed PMID: 31202098; PubMed Central PMCID: PMC6639125.
  • Robinson JG. Low LDL-C Levels: Likely No Short-Term Cognitive Harm. J Am Coll Cardiol. 2020 May 12;75(18):2294-2296. doi: 10.1016/j.jacc.2020.03.040. PubMed PMID: 32381159.
  • Wang J, Chi CL, St Peter WL, Carlson A, Loth M, Pradhan PM, Liang Y, Chen WY, Lenskaia T, Robinson JG, Adam TJ. A Population-Based Study of Simvastatin Drug-Drug Interactions in Cardiovascular Disease Patients. AMIA Jt Summits Transl Sci Proc. 2020 May 30;2020:664-673. eCollection 2020. PubMed PMID: 32477689; PubMed Central PMCID: PMC7233072.
  • Imamura F, Fretts AM, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Virtanen JK, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Chen YY, Wood AC, Del Gobbo LC, Djousse L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F; InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Riserus U, Robinson JG, Samieri C, Senn M, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Tuomainen TP, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JHY, Micha R, Lemaitre RN, Mozaffarian D, Forouhi NG. Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies. PLoS Med. 2020 Jun 12;17(6):e1003102. doi: 10.1371/journal.pmed.1003102. eCollection 2020 Jun. PubMed PMID: 32530938; PubMed Central PMCID: PMC7292352.
  • Koren MJ, Jones PH, Robinson JG, Sullivan D, Cho L, Hucko T, Lopez JAG, Fleishman AN, Somaratne R, Stroes E. A Comparison of Ezetimibe and Evolocumab for Atherogenic Lipid Reduction in Four Patient Populations: A Pooled Efficacy and Safety Analysis of Three Phase 3 Studies. Cardiol Ther. 2020 Jun 20. doi: 10.1007/s40119-020-00181-8. [Epub ahead of print] PubMed PMID: 32564340.
  • Lowenstern A, Li S, Virani SS, Navar AM, Li Z, Robinson JG, Roger VL, Goldberg AC, Koren A, Louie MJ, Peterson ED, Wang TY. Beliefs, risk perceptions, and lipid management among patients with and without diabetes: Results from the PALM registry. Am Heart J. 2020 Jul;225:88-96. doi: 10.1016/j.ahj.2020.04.018. Epub 2020 Apr 30. PMID: 32485329.
  • Gooding HC, Gidding SS, Moran AE, Redmond N, Allen NB, Bacha F, Burns TL, Catov JM, Grandner MA, Harris KM, Johnson HM, Kiernan M, Lewis TT, Matthews KA, Monaghan M, Robinson JG, Tate D, Bibbins-Domingo K, Spring B. Challenges and Opportunities for the Prevention and Treatment of Cardiovascular Disease Among Young Adults: Report From a National Heart, Lung, and Blood Institute Working Group. J Am Heart Assoc. 2020 Oct 20;9(19):e016115. doi: 10.1161/JAHA.120.016115. Epub 2020 Sep 30. PMID: 32993438.
  • Robinson JG, Jayanna MB, Bairey Merz CN, Stone NJ. Clinical implications of the log linear association between LDL-C lowering and cardiovascular risk reduction: Greatest benefits when LDL-C >100 mg/dl. PLoS One. 2020 Oct 29;15(10):e0240166. doi: 10.1371/journal.pone.0240166. PMID: 33119602; PMCID: PMC7595281.
  • Robinson JG. Low LDL-C Levels: Likely No Short-Term Cognitive Harm. J Am Coll Cardiol. 2020 May 12;75(18):2294-2296. doi: 10.1016/j.jacc.2020.03.040. PMID: 32381159.

Robert Roghair, MD:

  • Vass RA, Bell EF, Colaizy TT, Schmelzel ML, Johnson KJ, Walker JR, Ertl T, Roghair RD. Hormone levels in preterm and donor human milk before and after Holder pasteurization. Pediatr Res. 2020 Jan 30. doi: 10.1038/s41390-020-0789-6.  [Epub ahead of print] PubMed PMID: 32000260.
  • Vass RA, Roghair RD, Bell EF, Colaizy TT, Johnson KJ, Schmelzel ML, Walker JR, Ertl T. Pituitary Glycoprotein Hormones in Human Milk before and after Pasteurization or Refrigeration. Nutrients. 2020 Mar 4;12(3). pii: E687. doi: 10.3390/nu12030687. PubMed PMID: 32143273.

Stephen Russell, MD:

  •  Russell JF, Flynn HW Jr, Sridhar J, Townsend JH, Shi Y, Fan KC, Scott NL, Hinkle JW, Lyu C, Gregori G, Russell SR, Rosenfeld PJ. Distribution of Diabetic Neovascularization on Ultra-Widefield Fluorescein Angiography and on Simulated Widefield OCT Angiography. Am J Ophthalmol. 2019 Nov;207:110-120. doi: 10.1016/j.ajo.2019.05.031. Epub 2019 Jun 10. PubMed PMID: 31194952.
  • Al-Khersan H, Russell JF, Lazzarini TA, Scott NL, Hinkle JW, Patel NA, Yannuzzi NA, Fowler BJ, Hussain RM, Barikian A, Sridhar J, Russell SR, Haddock LJ, Smiddy WE, Hariprasad SM, Shi Y, Wang L, Feuer W, Gregori G, Rosenfeld PJ. Comparison Between Graders in Detection of Diabetic Neovascularization with Swept Source OCT Angiography and Fluorescein Angiography. Am J Ophthalmol. 2020 Dec 10:S0002-9394(20)30654-1. doi: 10.1016/j.ajo.2020.11.020. Epub ahead of print. PMID: 33309812

Tom Rutkowski, PhD:

  • Gansemer ER, McCommis KS, Martino M, King-McAlpin AQ, Potthoff MJ, Finck BN, Taylor EB, Rutkowski DT. NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis. iScience. 2020 May 22;23(5):101116. doi: 10.1016/j.isci.2020.101116. Epub 2020 Apr 29. PubMed PMID: 32417402; PubMed Central PMCID: PMC7254477.

Julien Sebag, PhD: 

  • Rouault AAJ, Rosselli-Murai LK, Hernandez CC, Gimenez LE, Tall GG, Sebag JA. The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a. Sci Signal. 2020 Jan 7;13(613). pii: eaax4569. doi: 10.1126/scisignal.aax4569. PubMed PMID: 31911434.
  • Yin TC, Bauchle CJ, Rouault AAJ, Stephens SB, Sebag JA. The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells. iScience. 2020 Jun 1;23(6):101216. doi: 10.1016/j.isci.2020.101216. [Epub ahead of print] PubMed PMID: 32535024; PubMed Central PMCID: PMC7300157.

Val Sheffield, MD, PhD:

  • Carter CS, Huang SC, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton AO Jr, Guo DF, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. Cell Metab. 2020 Oct 6;32(4):561-574.e7. doi: 10.1016/j.cmet.2020.09.012. PMID: 33027675.

Linda Snetselaar, PhD: 

  • Korth AL, Bhutani S, Neuhouser ML, Beresford SA, Snetselaar L, Tinker LF, Schoeller DA. Comparison of Methods Used to Correct Self-Reported Protein Intake for Systematic Variation in Reported Energy Intake Using Quantitative Biomarkers of Dietary Intake. J Nutr. 2020 Feb 6:nxaa007. doi: 10.1093/jn/nxaa007. Epub ahead of print. PMID: 32030414.
  • Chlebowski RT, Aragaki AK, Anderson GL, Pan K, Neuhouser ML, Manson JE, Thomson CA, Mossavar-Rahmani Y, Lane DS, Johnson KC, Wactawski-Wende J, Snetselaar L, Rohan TE, Luo J, Barac A, Prentice RL; Women’s Health Initiative. Dietary Modification and Breast Cancer Mortality: Long-Term Follow-Up of the Women's Health Initiative Randomized Trial. J Clin Oncol. 2020 Feb 7:JCO1900435. doi: 10.1200/JCO.19.00435. Epub ahead of print. PMID: 32031879.
  • Gong JH, Lo K, Liu Q, Li J, Lai S, Shadyab AH, Arcan C, Snetselaar L, Liu S. Dietary Manganese, Plasma Markers of Inflammation, and the Development of Type 2 Diabetes in Postmenopausal Women: Findings From the Women's Health Initiative. Diabetes Care. 2020 Jun;43(6):1344-1351. doi: 10.2337/dc20-0243. Epub 2020 Apr 15. PubMed PMID: 32295807.
  • Shadyab AH, Manson JE, Luo J, Haring B, Saquib N, Snetselaar LG, Chen JC, Groessl EJ, Wassertheil-Smoller S, Sun Y, Hale L, LeBoff MS, LaCroix AZ. Associations of Coffee and Tea Consumption With Survival to Age 90 Years Among Older Women. J Am Geriatr Soc. 2020 Apr 24. doi: 10.1111/jgs.16467. [Epub ahead of print] PubMed PMID: 32329900.
  • Yun HY, Tinker LF, Neuhouser ML, Schoeller DA, Mossavar-Rahmani Y, Snetselaar LG, Van Horn LV, Eaton CB, Prentice RL, Lampe JW, O'Brien DM. The Carbon Isotope Ratios of Serum Amino Acids in Combination with Participant Characteristics can be Used to Estimate Added Sugar Intake in a Controlled Feeding Study of US Postmenopausal Women. J Nutr. 2020 Jul 25:nxaa195. doi: 10.1093/jn/nxaa195. Epub ahead of print. PMID: 32712658.
  • Luo J, Chen X, Tindle H, Shadyab AH, Saquib N, Hale L, Garcia L, Springfield S, Liu B, Nassir R, Snetselaar L, Hendryx M. Do health behaviors mediate associations between personality traits and diabetes incidence? Ann Epidemiol. 2020 Aug 14:S1047-2797(20)30288-X. doi: 10.1016/j.annepidem.2020.08.007. Epub ahead of print. PMID: 32805399.
  • Chou EL, Pettinger M, Haring B, Mell MW, Hlatky MA, Wactawski-Wende J, Allison MA, Wild RA, Shadyab AH, Wallace RB, Snetselaar LG, Eagleton MJ, Conrad MF, Liu S. Lipoprotein(a) levels and risk of abdominal aortic aneurysm in the Women's Health Initiative. J Vasc Surg. 2020 Aug 31:S0741-5214(20)31908-X. doi: 10.1016/j.jvs.2020.07.106. Epub ahead of print. PMID: 32882349.
  • Chou EL, Pettinger M, Haring B, Allison MA, Mell MW, Hlatky MA, Wactawski-Wende J, Wild RA, Shadyab AH, Wallace RB, Snetselaar LG, Madsen TE, Eagleton MJ, Conrad MF, Liu S. Association of Premature Menopause With Risk of Abdominal Aortic Aneurysm in the Women's Health Initiative. Ann Surg. 2020 Nov 4. doi: 10.1097/SLA.0000000000004581. Epub ahead of print. PMID: 33156064.
  • Weaver CM, Fukagawa NK, Liska D, Mattes RD, Matuszek G, Nieves JW, Shapses SA, Snetselaar LG. Perspective: US Documentation and Regulation of Human Nutrition Randomized Controlled Trials. Adv Nutr. 2020 Nov 17:nmaa118. doi: 10.1093/advances/nmaa118. Epub ahead of print. PMID: 33200185.
  • Chen GC, Chen LH, Mossavar-Rahmani Y, Kamensky V, Shadyab AH, Haring B, Wild RA, Silver B, Kuller LH, Sun Y, Saquib N, Howard B, Snetselaar LG, Neuhouser ML, Allison MA, Van Horn L, Manson JE, Wassertheil-Smoller S, Qi Q. Dietary cholesterol and egg intake in relation to incident cardiovascular disease and all-cause and cause-specific mortality in postmenopausal women. Am J Clin Nutr. 2020 Dec 17:nqaa353. doi: 10.1093/ajcn/nqaa353. Epub ahead of print. PMID: 33330926.
  • George SM, Reedy J, Cespedes Feliciano EM, Aragaki A, Caan BJ, Kahle L, Manson JE, Rohan TE, Snetselaar LG, Tinker LF, Van Horn L, Neuhouser ML. Alignment of dietary patterns with the Dietary Guidelines for Americans 2015-2020 and risk of all-cause and cause-specific mortality in the Women's Health Initiative Observational Study. Am J Epidemiol. 2020 Dec 16:kwaa268. doi: 10.1093/aje/kwaa268. Epub ahead of print. PMID: 33325511.

Peter Snyder, MD: 

  • Polgreen LA, Carter BL, Polgreen PM, Snyder PM, Sewell DK, Bayman EO, Francis SL, Simmering JE, Parker C, Finkelstein R. A pharmacist intervention for monitoring and treating hypertension using bidirectional texting: PharmText BP. Contemp Clin Trials. 2020 Oct 7:106169. doi: 10.1016/j.cct.2020.106169. Epub ahead of print. PMID: 33038500.

Elliot Sohn, MD:

  • Kang SC, Sohn EH, Lee SR. Hydrogen Sulfide as a Potential Alternative for the  Treatment of Myocardial Fibrosis. Oxid Med Cell Longev. 2020 Jan 23;2020:4105382. doi: 10.1155/2020/4105382. eCollection 2020. Review. PubMed PMID: 32064023; PubMed Central PMCID: PMC6998763.
  • Han IC, Cheng JL, Burnight E, Ralston CL, Fick JL, Thomsen GJ, Tovar EF, Russell S, Sohn EH, Mullins RF, Stone E, Tucker BA, Wiley LA. Retinal Tropism and Transduction of Adeno-Associated Virus (AAV) Varies by Serotype and Route of Delivery (Intravitreal, Subretinal or Suprachoroidal) in Rats. Hum Gene Ther. 2020 Sep 18. doi: 10.1089/hum.2020.043. Epub ahead of print. PMID: 32948113.
  • Ricca A, Boone K, Boldt HC, Gehrs KM, Russell SR, Folk JC, Zimmerman MB, Wilkinson ME, Sohn EH. Attaining functional levels of visual acuity after vitrectomy for retinal detachment secondary to proliferative diabetic retinopathy. Sci Rep. 2020 Sep 24;10(1):15637. doi: 10.1038/s41598-020-72618-y. PMID: 32973186; PMCID: PMC7519031.

Milan Sonka, PhD

  • Bedanova H, Pazdernik M, Sonka M, Zhi C, Krejci J, Novakova M, Dobsak P, Nemec P. Effects of implanting a long-term left ventricle assist device on post-transplant outcomes. Int J Artif Organs. 2020 Apr 24:391398820914626. doi: 10.1177/0391398820914626. [Epub ahead of print] PubMed PMID: 32329386.
  • Minaee S, Kafieh R, Sonka M, Yazdani S, Jamalipour Soufi G. Deep-COVID: Predicting COVID-19 from chest X-ray images using deep transfer learning. Med Image Anal. 2020 Oct;65:101794. doi: 10.1016/j.media.2020.101794. Epub 2020 Jul 21. PMID: 32781377; PMCID: PMC7372265.
  • Pazdernik M, Bedanova H, Chen Z, Kautzner J, Melenovsky V, Malek I, Slavcev A, Bartonova M, Karmazin V, Eckhardt T, Tomasek A, Ozabalova E, Kovarnik T, Wohlfahrt P, Sonka M. Donor specific anti-HLA antibodies and cardiac allograft vasculopathy: A prospective study using highly automated 3-D optical coherence tomography analysis. Transpl Immunol. 2020 Oct 15:101340. doi: 10.1016/j.trim.2020.101340. Epub ahead of print. PMID: 33069814.
  • Guo Z, Zhang H, Chen Z, van der Plas E, Gutmann L, Thedens D, Nopoulos P, Sonka M. Fully automated 3D segmentation of MR-imaged calf muscle compartments: Neighborhood relationship enhanced fully convolutional network. Comput Med Imaging Graph. 2020 Dec 10;87:101835. doi: 10.1016/j.compmedimag.2020.101835. Epub ahead of print. PMID: 33373972.

Long Sheng-Song, MD:

  • Wang Y, Li C, Shi L, Chen X, Cui C, Huang J, Chen B, Hall DD, Pan Z, Lu M, Hong J, Song LS, Zhao S. Integrin β1D Deficiency-Mediated RyR2 Dysfunction Contributes to Catecholamine-Sensitive Ventricular Tachycardia in ARVC. Circulation. 2020 Mar 3. doi: 10.1161/CIRCULATIONAHA.119.043504. [Epub ahead of print] PubMed PMID: 32122157.
  • Wang J, Hall DD, Song LS. Nexilin is a New Player for Shaping T-Tubules in Cardiomyocytes. Circ Heart Fail. 2020 Jul;13(7):e007196. doi: 10.1161/CIRCHEARTFAILURE.120.007196. Epub 2020 Jul 8. PMID: 32635767; PMCID: PMC7375922.
  • Mesubi OO, Rokita AG, Abrol N, Wu Y, Chen B, Wang Q, Granger JM, Tucker-Bartley A, Luczak ED, Murphy KR, Umapathi P, Banerjee PS, Boronina T, Cole RN, Maier LS, Wehrens XH, Pomerantz JL, Song LS, Ahima R, Hart GW, Zachara NE, Anderson ME. Oxidized-CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms. J Clin Invest. 2020 Nov 5:95747. doi: 10.1172/JCI95747. Epub ahead of print. PMID: 33151911.

Douglas Spitz, PhD:

  • Falls-Hubert KC, Butler AL, Gui K, Anderson M, Li M, Stolwijk JM, Rodman SN 3rd, Solst SR, Tomanek-Chalkley A, Searby CC, Sheffield VC, Sandfort V, Schmidt H, McCormick ML, Wels BR, Allen BG, Buettner GR, Schultz MK, Spitz DR. Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper. Free Radic Biol Med. 2020 Feb 4;150:1-11. doi: 10.1016/j.freeradbiomed.2020.01.186. Epub ahead of print. PMID: 32032663.
  • Ubellacker JM, Tasdogan A, Ramesh V, Shen B, Mitchell EC, Martin-Sandoval MS, Gu Z, McCormick ML, Durham AB, Spitz DR, Zhao Z, Mathews TP, Morrison SJ. Lymph protects metastasizing melanoma cells from ferroptosis. Nature. 2020 Sep;585(7823):113-118. doi: 10.1038/s41586-020-2623-z. Epub 2020 Aug 19. PMID: 32814895; PMCID: PMC7484468.

Samuel Stephens, PhD: 

  • Huynh FK, Peterson BS, Anderson KA, Lin Z, Coakley AJ, Llaguno FMS, Nguyen TN, Campbell JE, Stephens SB, Newgard CB, Hirschey MD. Beta-cell specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice. Am J Physiol Endocrinol Metab. 2020 Aug 31. doi: 10.1152/ajpendo.00170.2020. Epub ahead of print. PMID: 32865009.

David Stoltz, MD, PhD:

  • Fischer AJ, Singh SB, LaMarche MM, Maakestad LJ, Kienenberger ZE, Peña TA, Stoltz DA, Limoli DH. Sustained Coinfections with Staphylococcus aureus and Pseudomonas aeruginosa in Cystic Fibrosis. Am J Respir Crit Care Med. 2020 Aug 4. doi: 10.1164/rccm.202004-1322OC. Epub ahead of print. PMID: 32750253.
  • Zarei K, Stroik MR, Gansemer ND, Thurman AL, Ostedgaard LS, Ernst SE, Thornell IM, Powers LS, Pezzulo AA, Meyerholz DK, Stoltz DA. Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Lab Invest. 2020 Jul 27. doi: 10.1038/s41374-020-0474-8. Epub ahead of print. PMID: 32719544.

Stefan Strack, PhD: 

  • Liu Y, Merrill RA, Strack S. A-Kinase Anchoring Protein 1: Emerging Roles in Regulating Mitochondrial Form and Function in Health and Disease. Cells. 2020 Jan 26;9(2). pii: E298. doi: 10.3390/cells9020298. Review. PubMed PMID: 31991888.
  • Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, Merrill RA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S. Deletion of a neuronal  Drp1 activator protects against cerebral ischemia. J Neurosci. 2020 Mar 3. pii: JN-RM-1926-19. doi: 10.1523/JNEUROSCI.1926-19.2020. [Epub ahead of print] PubMed  PMID: 32144179.
  • Jong CJ, Merrill RA, Wilkerson EM, Herring LE, Graves LM, Strack S. Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme. J Biol Chem. 2020 Mar 10. pii: jbc.RA119.011270. doi: 10.1074/jbc.RA119.011270. [Epub ahead of print] PubMed PMID: 32156701.
  • Edwards G, Perkins GA, Kim KY, Kong Y, Lee Y, Choi SH, Liu Y, Skowronska-Krawczyk D, Weinreb RN, Zangwill L, Strack S, Ju WK. Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells. Cell Death Dis. 2020 Apr 20;11(4):254. doi: 10.1038/s41419-020-2456-6. PubMed PMID: 32312949; PubMed Central PMCID: PMC7170863.
  • Song J, Merrill RA, Usachev AY, Strack S. The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades  doublecortin proteins to constrain neuronal dendritogenesis. J Biol Chem. 2020 Nov 16:jbc.RA120.016210. doi: 10.1074/jbc.RA120.016210. Epub ahead of print. PMID: 33199366.

Erin Talbert, PhD:

  • Montalvo RN, Doerr V, Kwon OS, Talbert EE, Yoo JK, Hwang MH, Nguyen BL, Christou DD, Kavazis AN, Smuder AJ. Protection against Doxorubicin-Induced Cardiac Dysfunction Is Not Maintained Following Prolonged Autophagy Inhibition. Int J Mol Sci. 2020 Oct 30;21(21):8105. doi: 10.3390/ijms21218105. PMID: 33143122; PMCID: PMC7662380.

Eric Taylor, PhD:

  • Buchanan JL, Taylor EB. Mitochondrial Pyruvate Carrier Function in Health and Disease across the Lifespan. Biomolecules. 2020 Aug 8;10(8):E1162. doi: 10.3390/biom10081162. PMID: 32784379.

Eva Tsalikian, MD:

  • Harrison K, Afifi T, Zamanzadeh N, Davis S, Ersig A, Tsalikian E, Acevedo Callejas M. Parents' relationship maintenance as a buffer for the stress of their adolescent's type 1 diabetes. J Fam Psychol. 2020 Mar 12. doi: 10.1037/fam0000634. [Epub ahead of print] PubMed PMID: 32162943.
  • Sinha S, Renavikar PS, Crawford MP, Steward-Tharp SM, Brate A, Tsalikian E, Tansey M, Shivapour ET, Cho T, Kamholz J, Karandikar NJ. Altered expression of SIRPγ on the T-cells of relapsing remitting multiple sclerosis and type 1 diabetes patients could potentiate effector responses from T-cells. PLoS One. 2020 Aug 27;15(8):e0238070. doi: 10.1371/journal.pone.0238070. PMID: 32853219; PMCID: PMC7451561.
  • Lagarde WH, Courtney KL, Reiner B, Steinmann K, Tsalikian E, Willi SM. Human plasma-derived alpha1 -proteinase inhibitor in patients with new-onset type 1 diabetes mellitus: A randomized, placebo-controlled proof-of-concept study. Pediatr Diabetes. 2020 Nov 26. doi: 10.1111/pedi.13162. Epub ahead of print. PMID: 33244872.

Aliye Uc, MD: 

  • Ellery KM, Uc A. Recurrent Pancreatitis in Children: Past, Present, and Future. J Pediatr Gastroenterol Nutr. 2019 Dec 30. doi: 10.1097/MPG.0000000000002619. [Epub ahead of print] PubMed PMID: 31899736.
  • ​Dike CR, Zimmerman B, Zheng Y, Wilschanski M, Werlin SL, Troendle D, Shah U, Schwarzenberg SJ, Pohl J, Perito ER, Ooi CY, Nathan JD, Morinville VD, McFerron B, Mascarenhas M, Maqbool A, Liu Q, Lin TK, Husain SZ, Heyman MB, Gonska T, Giefer MJ, Gariepy CE, Fishman DS, Bellin M, Barth B, Abu-El-Haija M, Lowe ME, Uc A. Clinical and Practice Variations in Pediatric Acute Recurrent or Chronic Pancreatitis: Report From The Insppire Study. J Pediatr Gastroenterol Nutr. 2020 Feb 19. doi: 10.1097/MPG.0000000000002661. [Epub ahead of print] PubMed PMID: 32079978.
  • Abu-El-Haija M, Lowe M, Barth B, Bellin MD, Freedman S, Gariepy C, Giefer MJ, Gonska T, Heyman MB, Himes R, Husain S, Lin TK, Liu Q, Mascarenhas MR, Maqbool A, McFerron B, Morinville V, Nathan J, Ooi CY, Perito E, Pohl JF, Schwarzenberg SJ, Shah U, Troendle D, Werlin S, Wilschanski M, Zimmerman B, Uc A. Pediatric chronic pancreatitis without prior acute or acute recurrent pancreatitis: A report from the INSPPIRE consortium. Pancreatology. 2020 Apr 9. pii: S1424-3903(20)30130-7. doi: 10.1016/j.pan.2020.04.001. [Epub ahead of print] PubMed PMID: 32332002
  • Dike CR, Vanegas Calderon OG, Bishop W, Uc A. Drug-Induced Pancreatitis in a Pediatric Patient Following Acetaminophen Overdose. Pancreas. 2020 May/Jun;49(5):e45-e46. doi: 10.1097/MPA.0000000000001555. PubMed PMID: 32433416.
  • Dike CR, Kao SC, Uc A. Progression from acute to chronic pancreatitis associated with CFTR and SPINK1 mutations. Pancreatology. 2020 Jun 6. pii: S1424-3903(20)30163-0. doi: 10.1016/j.pan.2020.05.012. [Epub ahead of print] PubMed PMID: 32553420.

Yuriy Usachev, PhD:

  • Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, MerrillRA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S. Deletion of a neuronal Drp1 activator protects against cerebral ischemia. J Neurosci. 2020 Mar 3. pii: JN-RM-1926-19. doi: 10.1523/JNEUROSCI.1926-19.2020. [Epub ahead of print] PubMed  PMID: 32144179.

Ajit Vikram, PhD: 

  • Gaddam RR, Jacobsen VP, Kim YR, Gabani M, Jacobs JS, Dhuri K, Kumar S, Kassan M, Li Q, Bahal R, Roghair R, Irani K, Vikram A. Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice. Sci Rep. 2020 Jun 22;10(1):10065. doi: 10.1038/s41598-020-66786-0. PubMed PMID: 32572127; PubMed Central PMCID: PMC7308358.
  • Dhuri K, Bechtold C, Quijano E, Pham H, Gupta A, Vikram A, Bahal R. Antisense  Oligonucleotides: An Emerging Area in Drug Discovery and Development. J Clin Med. 2020 Jun 26;9(6). pii: E2004. doi: 10.3390/jcm9062004. Review. PubMed PMID: 32604776.
  • Gaddam RR, Kim YR, Li Q, Jacobs JS, Gabani M, Mishra A, Promes JA, Imai Y, Irani K, Vikram A. Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice. Biochem Biophys Res Commun. 2020 Nov 5;532(2):167-172. doi: 10.1016/j.bbrc.2020.08.077. Epub 2020 Sep 17. PMID: 32950230.

Michael Welsh, MD: 

  • Rehman T, Thornell IM, Pezzulo AA, Thurman AL, Romano Ibarra GS, Karp PH, Tan P, Duffey ME, Welsh MJ. TNFα and IL-17 Alkalinize Airway Surface Liquid through CFTR and Pendrin. Am J Physiol Cell Physiol. 2020 May 20. doi: 10.1152/ajpcell.00112.2020. [Epub ahead of print] PubMed PMID: 32432926.
  • Thornell IM, Rehman T, Pezzulo AA, Welsh MJ. Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH. J Physiol. 2020 Jul 5. doi: 10.1113/JP280120. [Epub ahead of print] PubMed PMID: 32627187.
  • Xie Y, Lu L, Tang XX, Moninger TO, Huang TJ, Stoltz DA, Welsh MJ. Acidic Submucosal Gland pH and Elevated Protein Concentration Produce Abnormal Cystic Fibrosis Mucus. Dev Cell. 2020 Jul 23:S1534-5807(20)30550-5. doi: 10.1016/j.devcel.2020.07.002. Epub ahead of print. PMID: 32730755.
  • Ostedgaard LS, Price MP, Whitworth KM, Abou Alaiwa MH, Fischer AJ, Warrier A, Samuel M, Spate LD, Allen PD, Hilkin BM, Romano Ibarra GS, Ortiz Bezara ME, Goodell BJ, Mather SE, Powers LS, Stroik MR, Gansemer ND, Hippee CE, Zarei K, Goeken JA, Businga TR, Hoffman EA, Meyerholz DK, Prather RS, Stoltz DA, Welsh MJ. Lack of airway submucosal glands impairs respiratory host defenses. Elife. 2020 Oct 7;9:e59653. doi: 10.7554/eLife.59653. PMID: 33026343; PMCID: PMC7541087.
  • Chorghade RS, Kim BR, Launspach JL, Karp PH, Welsh MJ, Burke MD. Amphotericin B induces epithelial voltage responses in people with cystic fibrosis. J Cyst Fibros. 2020 Dec 8:S1569-1993(20)30928-0. doi: 10.1016/j.jcf.2020.11.018. Epub ahead of print. PMID: 33309058.

Ling Yang, PhD:

  • Zhang Z, Qian Q, Li M, Shao F, Ding WX, Lira VA, Chen SX, Sebag SC, Hotamisligil GS, Cao H, Yang L. The Unfolded Protein Response Regulates Hepatic Autophagy by sXBP1-mediated Activation of TFEB. Autophagy. 2020 Jun 28. doi: 10.1080/15548627.2020.1788889. [Epub ahead of print] PubMed PMID: 32597296.

Mark Yorek, PhD:

  • Coppey L, Davidson E, Shevalye H, Obrosov A, Torres M, Yorek MA. Progressive Loss of Corneal Nerve Fibers and Sensitivity in Rats Modeling Obesity and Type 2 Diabetes Is Reversible with Omega-3 Fatty Acid Intervention: Supporting Cornea Analyses as a Marker for Peripheral Neuropathy and Treatment. Diabetes Metab Syndr Obes. 2020 Apr 24;13:1367-1384. doi: 10.2147/DMSO.S247571. eCollection 2020. PubMed PMID: 32425569; PubMed Central PMCID: PMC7189026.
  • Andreasen LJ, Kirk RK, Fledelius C, Yorek MA, Lykkesfeldt J, Akerstrom T. Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes. J Diabetes Res. 2020 Aug 2;2020:9626398. doi: 10.1155/2020/9626398. PMID: 32832565; PMCID: PMC7424504.
  • Strom A, Strassburger K, Schmuck M, Shevalye H, Davidson E, Zivehe F, Bönhof G, Reimer R, Belgardt BF, Fleming T, Biermann B, Burkart V, Müssig K, Szendroedi J, Yorek MA, Fritsche E, Nawroth PP, Roden M, Ziegler D; GDS Group. Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models. Mol Metab. 2020 Nov 6:101114. doi: 10.1016/j.molmet.2020.101114. Epub ahead of print. PMID: 33166742