2021

Francois Abboud, MD, PhD:

• Abboud FM. Four evolving concepts in molecular and clinical autonomic research. Clin Auton Res. 2021 Jun 30. doi: 10.1007/s10286-021-00816-3. Epub ahead of print. PMID: 34191210.

E. Dale Abel, MD, PhD: 

• Tang M, Park SH, Petri S, Yu H, Rueda CB, Abel ED, Kim CY, Hillman EM, Li F, Lee Y, Ding L, Jagadish S, Frankel WN, De Vivo DC, Monani UR. An early endothelial cell-specific requirement for Glut1 is revealed in Glut1 deficiency syndrome model mice. JCI Insight. 2021 Feb 8;6(3):e145789. doi: 10.1172/jci.insight.145789. PMID: 33351789; PMCID: PMC7934852.
• Weeks KL, Tham YK, Yildiz SG, Alexander Y, Donner DG, Kiriazis H, Harmawan CA, Hsu AT, Bernardo BC, Matsumoto A, DePinho RA, Abel ED, Woodcock EA, McMullen JR. FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K. Am J Physiol Heart Circ Physiol. 2021 Feb 12. doi: 10.1152/ajpheart.00838.2020. Epub ahead of print. PMID: 33577435.
• Ancey PB, Contat C, Boivin G, Sabatino S, Pascual J, Zangger N, Perentes JY, Peters S, Abel ED, Kirsch DG, Rathmell JC, Vozenin MC, Meylan E. Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy. Cancer Res. 2021 Mar 22:canres.2870.2020. doi: 10.1158/0008-5472.CAN-20-2870. Epub ahead of print. PMID: 33753374.
• Carter CS, Huang S, Searby C, Cassaidy B, Miller M, Grzesik W, Piorczynski TB, Pak TK, Walsh S, Acevedo M, Zhang Q, Mapuskar K, Milne G, Hinton AO Jr, Guo DF, Weiss RM, Bradberry K, Taylor EB, Rauckhorst A, Dick D, Akurathi V, Falls-Hubert K, Wagner B, Carter W, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Response to: An alternative hypothesis for why exposure to static magnetic and electric fields treats type 2 diabetes. Am J Physiol Endocrinol Metab. 2021 Apr 12. doi: 10.1152/ajpendo.00119.2021. Epub ahead of print. PMID: 33843283.
• Carter CS, Huang S, Searby C, Cassaidy B, Miller M, Grzesik W, Piorczynski TB, Pak TK, Walsh S, Acevedo M, Zhang Q, Mapuskar K, Milne G, Hinton AO Jr, Guo DF, Weiss RM, Bradberry K, Taylor EB, Rauckhorst A, Dick D, Akurathi V, Falls-Hubert K, Wagner B, Carter W, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Counterpoint regarding an alternative hypothesis for why exposure to static magnetic and electric fields treat type 2 diabetes. Am J Physiol Endocrinol Metab. 2021 Apr 12. doi: 10.1152/ajpendo.00110.2021. Epub ahead of print. PMID: 33843282.
• Finn PW, Abel ED, Amin A, Anderson ME, Carethers JM, Coleman DL, Curtis AB, Geraci MW, Gladwin MT, Hollenberg A, Parmacek MS, Robbins RJ. Voices for Social Justice and Against Racism: An AAIM Perspective. Am J Med. 2021 Apr 10:S0002-9343(21)00219-9. doi: 10.1016/j.amjmed.2021.03.008. Epub ahead of print. PMID: 33848502.
• Pereira RO, Marti A, Olvera AC, Tadinada SM, Bjorkman SH, Weatherford ET, Morgan DA, Westphal M, Patel PH, Kirby AK, Hewezi R, Bùi Trân W, García-Peña LM, Souvenir RA, Mittal M, Adams CM, Rahmouni K, Potthoff MJ, Abel ED. OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21. Elife. 2021 May 4;10:e66519. doi: 10.7554/eLife.66519. PMID: 33944779; PMCID: PMC8128440.
• Byrne NJ, Rajasekaran NS, Abel ED, Bugger H. Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy. Free Radic Biol Med. 2021 Jun;169:317-342. doi: 10.1016/j.freeradbiomed.2021.03.046. Epub 2021 Apr 25. PMID: 33910093.
• Veys K, Fan Z, Ghobrial M, Bouché A, García-Caballero M, Vriens K, Conchinha NV, Seuwen A, Schlegel F, Gorski T, Crabbé M, Gilardoni P, Ardicoglu R, Schaffenrath J, Casteels C, De Smet G, Smolders I, Van Laere K, Abel ED, Fendt SM, Schroeter A, Kalucka J, Cantelmo AR, Wälchli T, Keller A, Carmeliet P, De Bock K. Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity. Circ Res. 2020 Jul 31;127(4):466-482. doi: 10.1161/CIRCRESAHA.119.316463. Epub 2020 May 14. PMID: 32404031; PMCID: PMC7386868.
• Lopaschuk GD, Karwi QG, Tian R, Wende AR, Abel ED. Cardiac Energy Metabolism in Heart Failure. Circ Res. 2021 May 14;128(10):1487-1513. doi: 10.1161/CIRCRESAHA.121.318241. Epub 2021 May 13. PMID: 33983836; PMCID: PMC8136750.
• Abel ED. Insulin Signaling In the Heart. Am J Physiol Endocrinol Metab. 2021 May 31. doi: 10.1152/ajpendo.00158.2021. Epub ahead of print. PMID: 34056923.
• Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG. The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure. Circulation. 2020 Jul 21;142(3):259-274. doi: 10.1161/CIRCULATIONAHA.119.044452. Epub 2020 Apr 30. PMID: 32351122; PMCID: PMC7380956.
• Tadinada SM, Weatherford ET, Collins GV, Bhardwaj G, Cochran J, Kutschke W, Zimmerman K, Bosko A, O'Neill BT, Weiss RM, Abel ED. FUNCTIONAL RESILIENCE OF C57BL/6J MOUSE HEART TO DIETARY FAT OVERLOAD. Am J Physiol Heart Circ Physiol. 2021 Sep 3. doi: 10.1152/ajpheart.00419.2021. Epub ahead of print. PMID: 34477461.
• Lam J, Katti P, Biete M, Mungai M, AshShareef S, Neikirk K, Garza Lopez E, Vue Z, Christensen TA, Beasley HK, Rodman TA, Murray SA, Salisbury JL, Glancy B, Shao J, Pereira RO, Abel ED, Hinton A Jr. A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ. Cells. 2021 Aug 24;10(9):2177. doi: 10.3390/cells10092177. PMID: 34571826; PMCID: PMC8465115.
• Morales PE, Monsalves-Álvarez M, Tadinada SM, Harris MP, Ramírez-Sagredo A, Ortiz-Quintero J, Troncoso MF, De Gregorio N, Calle X, Pereira RO, Lira VA, Espinosa A, Abel ED, Lavandero S. Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation. FASEB J. 2021 Oct;35(10):e21933. doi: 10.1096/fj.202001593RR. PMID: 34555201.
• Tadinada SM, Weatherford ET, Collins GV, Bhardwaj G, Cochran J, Kutschke W, Zimmerman K, Bosko A, O'Neill BT, Weiss RM, Abel ED. Functional resilience of C57BL/6J mouse heart to dietary fat overload. Am J Physiol Heart Circ Physiol. 2021 Nov 1;321(5):H850-H864. doi: 10.1152/ajpheart.00419.2021. Epub 2021 Sep 3. PMID: 34477461.
• Morales PE, Monsalves-Álvarez M, Tadinada SM, Harris MP, Ramírez-Sagredo A, Ortiz-Quintero J, Troncoso MF, De Gregorio N, Calle X, Pereira RO, Lira VA, Espinosa A, Abel ED, Lavandero S. Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation. FASEB J. 2021 Oct;35(10):e21933. doi: 10.1096/fj.202001593RR. PMID: 34555201
• Garza-Lopez E, Vue Z, Katti P, Neikirk K, Biete M, Lam J, Beasley HK, Marshall AG, Rodman TA, Christensen TA, Salisbury JL, Vang L, Mungai M, AshShareef S, Murray SA, Shao J, Streeter J, Glancy B, Pereira RO, Abel ED, Hinton A Jr. Protocols for Generating Surfaces and Measuring 3D Organelle Morphology Using Amira. Cells. 2021 Dec 27;11(1):65. doi: 10.3390/cells11010065. PMID: 35011629; PMCID: PMC8750564.

Michael Abramoff, MD, PhD: 

• Wolf RM, Liu TYA, Thomas C, Prichett L, Zimmer Galler I, Smith K, Abramoff MD, Channa R. The SEE Study: Safety, Efficacy, and Equity of Implementing Autonomous Artificial Intelligence for Diagnosing Diabetic Retinopathy in Youth. Diabetes Care. 2021 Jan 21:dc201671. doi: 10.2337/dc20-1671. Epub ahead of print. PMID: 33479160.
• Thomas CG, Channa R, Prichett L, Liu TYA, Abramoff MD, Wolf RM. Racial/Ethnic Disparities and Barriers to Diabetic Retinopathy Screening in Youths. JAMA Ophthalmol. 2021 May 27:e211551. doi: 10.1001/jamaophthalmol.2021.1551. Epub ahead of print. PMID: 34042939; PMCID: PMC8160913.
• Abramoff MD, Cunningham B, Patel B, Eydelman MB, Leng T, Sakamoto T, Blodi B, Grenon SM, Wolf RM, Manrai AK, Ko JM, Chiang MF, Char D; Collaborative Community on Ophthalmic Imaging Executive Committee and Foundational Principles of Ophthalmic Imaging and Algorithmic Interpretation Working Group. Foundational Considerations for Artificial Intelligence Utilizing Ophthalmic Images. Ophthalmology. 2021 Aug 31:S0161-6420(21)00643-6. doi: 10.1016/j.ophtha.2021.08.023. Epub ahead of print. PMID: 34478784.
• Channa R, Lee K, Staggers KA, Mehta N, Zafar S, Gao J, Frankfort BJ, Chua SYL, Khawaja AP, Foster PJ, Patel PJ, Minard CG, Amos C, Abramoff MD. Detecting retinal neurodegeneration in people with diabetes: Findings from the UK Biobank. PLoS One. 2021 Sep 29;16(9):e0257836. doi: 10.1371/journal.pone.0257836. PMID: 34587216; PMCID: PMC8480885.
• Sounderajah V, Ashrafian H, Rose S, Shah NH, Ghassemi M, Golub R, Kahn CE Jr, Esteva A, Karthikesalingam A, Mateen B, Webster D, Milea D, Ting D, Treanor D, Cushnan D, King D, McPherson D, Glocker B, Greaves F, Harling L, Ordish J, Cohen JF, Deeks J, Leeflang M, Diamond M, McInnes MDF, McCradden M, Abràmoff MD, Normahani P, Markar SR, Chang S, Liu X, Mallett S, Shetty S, Denniston A, Collins GS, Moher D, Whiting P, Bossuyt PM, Darzi A. A quality assessment tool for artificial intelligence-centered diagnostic test accuracy studies: QUADAS-AI. Nat Med. 2021 Oct;27(10):1663-1665. doi: 10.1038/s41591-021-01517-0. PMID: 34635854.

Ferhaan Ahmad, MD, PhD:

• Pereira NL, Ahmad F, Byku M, Cummins NW, Morris AA, Owens A, Tuteja S, Cresci S. COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine. Mayo Clin Proc. 2021 Feb;96(2):446-463. doi: 10.1016/j.mayocp.2020.11.024. Epub 2020 Dec 3. PMID: 33549263; PMCID: PMC7713605.
• Cresci S, Ahmad F, Pereira NL. In reply-COVID-19: Precision Medicine and Vascular Endothelium. Mayo Clin Proc. 2021 Jun;96(6):1672. doi: 10.1016/j.mayocp.2021.04.006. Epub 2021 Apr 19. PMID: 34088425; PMCID: PMC8055184.

Ethan Anderson, PhD:

• Mattox TA, Psaltis C, Weihbrecht K, Robidoux J, Kilburg-Basnyat B, Murphy MP, Gowdy KM, Anderson EJ. Prohibitin-1 Is a Dynamically Regulated Blood Protein With Cardioprotective Effects in Sepsis. J Am Heart Assoc. 2021 Jul 3:e019877. doi: 10.1161/JAHA.120.019877. Epub ahead of print. PMID: 34219469.
• Crawford RA, Gilardoni E, Monroe TB, Regazzoni L, Anderson EJ, Doorn JA. Characterization of Catecholaldehyde Adducts with Carnosine and l-Cysteine Reveals Their Potential as Biomarkers of Catecholaminergic Stress. Chem Res Toxicol. 2021 Sep 10. doi: 10.1021/acs.chemrestox.1c00153. Epub ahead of print. PMID: 34506109.
• Monroe TB, Anderson EJ. A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l-Carnosine. Chem Res Toxicol. 2021 Oct 5. doi: 10.1021/acs.chemrestox.1c00262. Epub ahead of print. PMID: 34609854.

Michael Anderson, PhD: 

• Harper MM, Boehme N, Dutca LM, Anderson MG. The Retinal Ganglion Cell Response to Blast-Mediated Traumatic Brain Injury Is Genetic Background Dependent. Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):13. doi: 10.1167/iovs.62.7.13. PMID: 34106210.
• Boehme NA, Hedberg-Buenz A, Tatro N, Bielecki M, Castonguay WC, Scheetz TE, Anderson MG, Dutca LM. Axonopathy precedes cell death in ocular damage mediated by blast exposure. Sci Rep. 2021 Jun 3;11(1):11774. doi: 10.1038/s41598-021-90412-2. PMID: 34083587; PMCID: PMC8175471.

James Ankrum, PhD: 

• Burand AJ Jr, Di L, Boland LK, Boyt DT, Schrodt MV, Santillan DA, Ankrum JA. Aggregation of Human Mesenchymal Stromal Cells Eliminates Their Ability to Suppress Human T Cells. Front Immunol. 2020 Feb 25;11:143. doi: 10.3389/fimmu.2020.00143. PMID: 32158443; PMCID: PMC7052295.

Mark Arnold, PhD: 

• Ye M, Arnold MA. Selectivity and Sensitivity of Near-Infrared Spectroscopic Sensing of β-Hydroxybutyrate, Glucose, and Urea in Ternary Aqueous Solutions. Anal Chem. 2021 Apr 6;93(13):5586-5595. doi: 10.1021/acs.analchem.1c00300. Epub 2021 Mar 24. PMID: 33760590.
• Shang T, Zhang JY, Thomas A, Arnold MA, Vetter BN, Heinemann L, Klonoff DC. Products for Monitoring Glucose Levels in the Human Body with Noninvasive Optical, Noninvasive Fluid Sampling, or Minimally Invasive Technologies. J Diabetes Sci Technol. 2021 Jun 13:19322968211007212. doi: 10.1177/19322968211007212. Epub ahead of print. PMID: 34120487.
• Klonoff DC, Nguyen KT, Xu NY, Arnold MA. Noninvasive Glucose Monitoring: In God We Trust-All Others Bring Data. J Diabetes Sci Technol. 2021 Oct 21:19322968211046326. doi: 10.1177/19322968211046326. Epub ahead of print. PMID: 34672216.

Wei Bao, MD, PhD: 

• Jin Q, Shi N, Aroke D, Lee DH, Joseph JJ, Donneyong M, Conwell DL, Hart PA, Zhang X, Clinton SK, Cruz-Monserrate Z, Brasky TM, Jackson R, Tinker LF, Liu S, Phillips LS, Shadyab AH, Nassir R, Bao W, Tabung FK. Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women. Diabetes Care. 2021 Jan 8:dc202216. doi: 10.2337/dc20-2216. Epub ahead of print. PMID: 33419931.
• Tang J, Chen R, Yu Y, Bao W, Tiemeier H, Rodney A, Zhu X, Li M, Huang D, Zhao Q. Associations of pre-pregnancy impaired fasting glucose and body mass index among pregnant women without pre-existing diabetes with offspring being large for gestational age and preterm birth: a cohort study in China. BMJ Open Diabetes Res Care. 2021 Feb;9(1):e001641. doi: 10.1136/bmjdrc-2020-001641. PMID: 33568359.
• Jasper EA, Cho H, Breheny PJ, Bao W, Dagle JM, Ryckman KK. Perinatal determinants of growth trajectories in children born preterm. PLoS One. 2021 Jan 28;16(1):e0245387. doi: 10.1371/journal.pone.0245387. PMID: 33507964; PMCID: PMC7842887.
• Tang J, Zhu X, Chen Y, Huang D, Tiemeier H, Chen R, Bao W, Zhao Q. Association of maternal pre-pregnancy low or increased body mass index with adverse pregnancy outcomes. Sci Rep. 2021 Feb 15;11(1):3831. doi: 10.1038/s41598-021-82064-z. PMID: 33589654; PMCID: PMC7884680.
• Zheng X, Yang D, Luo S, Yan J, Guo X, Yang H, Bao W, Groop L, Dornhorst A, Weng J; CARNATION Study Group. Association of Implementation of a Comprehensive Preconception-to-Pregnancy Management Plan With Pregnancy Outcomes Among Chinese Pregnant Women With Type 1 Diabetes: The CARNATION Study. Diabetes Care. 2021 Feb 24:dc202692. doi: 10.2337/dc20-2692. Epub ahead of print. PMID: 33627365.
• Liu B, Du Y, Wu Y, Snetselaar LG, Wallace RB, Bao W. Trends in obesity and adiposity measures by race or ethnicity among adults in the United States 2011-18: population based study. BMJ. 2021 Mar 16;372:n365. doi: 10.1136/bmj.n365. PMID: 33727242.
• Sun Y, Liu B, Snetselaar LG, Wallace RB, Shadyab AH, Kroenke CH, Haring B, Howard BV, Shikany JM, Valdiviezo C, Bao W. Association of Major Dietary Protein Sources With All-Cause and Cause-Specific Mortality: Prospective Cohort Study. J Am Heart Assoc. 2021 Feb;10(5):e015553. doi: 10.1161/JAHA.119.015553. Epub 2021 Feb 24. PMID: 33624505.
• Trim A, Hankinson SE, Liu S, Shadyab AH, Meliker J, Bao W, Luo J, Liu B, Manson JE, Tinker L, Bigelow C, Reeves KW. Biomarkers of phthalates and inflammation: Findings from a subgroup of Women's Health Initiative participants. Int J Hyg Environ Health. 2021 Apr 1;234:113743. doi: 10.1016/j.ijheh.2021.113743. Epub ahead of print. PMID: 33813346.
• Lan T, Liu B, Bao W, Thorne PS. BMI modifies the association between dietary intake and serum levels of PCBs. Environ Int. 2021 May 24;156:106626. doi: 10.1016/j.envint.2021.106626. Epub ahead of print. PMID: 34034117.
• Zhang X, Gong Y, Della Corte K, Yu D, Xue H, Shan S, Tian G, Liang Y, Zhang J, He F, Yang D, Zhou R, Bao W, Buyken AE, Cheng G. Relevance of dietary glycemic index, glycemic load and fiber intake before and during pregnancy for the risk of gestational diabetes mellitus and maternal glucose homeostasis. Clin Nutr. 2021 Apr 5;40(5):2791-2799. doi: 10.1016/j.clnu.2021.03.041. Epub ahead of print. PMID: 33933745.
• Qi Q, Li J, Yu B, Moon JY, Chai JC, Merino J, Hu J, Ruiz-Canela M, Rebholz C, Wang Z, Usyk M, Chen GC, Porneala BC, Wang W, Nguyen NQ, Feofanova EV, Grove ML, Wang TJ, Gerszten RE, Dupuis J, Salas-Salvadó J, Bao W, Perkins DL, Daviglus ML, Thyagarajan B, Cai J, Wang T, Manson JE, Martínez-González MA, Selvin E, Rexrode KM, Clish CB, Hu FB, Meigs JB, Knight R, Burk RD, Boerwinkle E, Kaplan RC. Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies. Gut. 2021 Jun 14:gutjnl-2021-324053. doi: 10.1136/gutjnl-2021-324053. Epub ahead of print. PMID: 34127525.
• Schneider AC, Moon C, Whitaker K, Zhang D, Carr LJ, Bao W, Xiao Q. Association of Sleep With Risk of Alzheimer's Disease Mortality: NIH-AARP Diet and Health Study. J Appl Gerontol. 2021 Jun 10:7334648211019207. doi: 10.1177/07334648211019207. Epub ahead of print. PMID: 34109847.
• Zhang L, Li T, Chen L, Wu F, Xia W, Huang M, Guo Z, Song L, Yin H, Zhang Y, Yu Y, Cai S, Lu Z, Rong S, Bao W. Association of sleep quality before and after SARS-CoV-2 infection with clinical outcomes in hospitalized patients with COVID-19 in China. EXCLI J. 2021 Apr 14;20:894-906. doi: 10.17179/excli2021-3451. PMID: 34121976; PMCID: PMC8192881.
• Qin Y, Jiao C, Huang S, Li Y, Zhang Z, Bao W, Mao L. "Zuòyuèzi" dietary and behavioural associations with maternal health among puerperal women in South China. Asia Pac J Clin Nutr. 2021 Jun;30(2):291-302. doi: 10.6133/apjcn.202106_30(2).0014. PMID: 34191432.
• Wang Y, Wu L, Yang Z, Xu R, Duan Y, Lin J, Cui X, Fan C, Zhou Y, Bao W, Jin L, Liu Y. Association of body mass index with serum anti-Müllerian hormone and inhibin B levels among 8323 women attending a reproductive medical center: a cross-sectional study. Endocrine. 2021 Aug 7. doi: 10.1007/s12020-021-02839-2. Epub ahead of print. PMID: 34363585.
• Shadyab AH, McEvoy LK, Horvath S, Whitsel EA, Rapp SR, Espeland MA, Resnick SM, Manson JE, Chen JC, Chen BH, Li W, Hayden KM, Bao W, Kusters CDJ, LaCroix AZ. Association of Epigenetic Age Acceleration with Incident Mild Cognitive Impairment and Dementia Among Older Women. J Gerontol A Biol Sci Med Sci. 2021 Aug 21:glab245. doi: 10.1093/gerona/glab245. Epub ahead of print. PMID: 34417803.
• Hinkle SN, Bao W, Wu J, Sun Y, Ley SH, Tobias DK, Qian F, Rawal S, Zhu Y, Chavarro JE, Hu FB, Zhang C. Association of Habitual Alcohol Consumption With Long-term Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes. JAMA Netw Open. 2021 Sep 1;4(9):e2124669. doi: 10.1001/jamanetworkopen.2021.24669. PMID: 34499132.
• Chen Y, Qin Y, Zhang Z, Huang S, Jiao C, Zhang Z, Bao W, Mao L. Association of the low-carbohydrate dietary pattern with postpartum weight retention in women. Food Funct. 2021 Oct 5. doi: 10.1039/d1fo00935d. Epub ahead of print. PMID: 34609398.
• Trasande L, Liu B, Bao W. Phthalates and attributable mortality: A population-based longitudinal cohort study and cost analysis. Environ Pollut. 2021 Sep 11:118021. doi: 10.1016/j.envpol.2021.118021. Epub ahead of print. PMID: 34654571.
• Luo S, Ran X, Zhang M, Ji H, Yang D, Zhu D, Zhao J, Xiao X, Guo X, Yang T, Huang Q, Liu F, Lu J, Ma J, Zhou X, Ping F, Nan G, Wenwen L, Yang Y, Fang C, Bao W, Zheng X, Yan J, Zhou Z, Weng J. Pregnancy outcomes in women with type 1 diabetes in China during 2004 - 2014: a retrospective study (the CARNATION Study). J Diabetes. 2021 Oct 7. doi: 10.1111/1753-0407.13229. Epub ahead of print. PMID: 34617682.

Melissa Bates, PhD:

• Vasilyev M, Berschel MR, Tomasson MH, Bates ML. Viewpoint: Time to stop treating the heart as a single organ? Exp Physiol. 2021 Mar 17. doi: 10.1113/EP089497. Epub ahead of print. PMID: 33728739.
• Pottebaum E, Warmoth A, Ayyappan S, Dickens DS, Jethava Y, Modi A, Tomasson MH, Carr LJ, Bates ML. Wearable Monitors Facilitate Exercise in Adult and Pediatric Stem Cell Transplant. Exerc Sport Sci Rev. 2021 Apr 22. doi: 10.1249/JES.0000000000000258. Epub ahead of print. PMID: 33927164.
• Amaza I, Kalra H, Eberlein M, Jethava Y, McDonell J, Wolfe B, Tomasson MH, Bates ML. Case Studies in Physiology: Untangling the cause of hypoxemia in an obese patient with acute leukemia. J Appl Physiol (1985). 2021 May 6. doi: 10.1152/japplphysiol.00867.2020. Epub ahead of print. PMID: 33955261.
• Bates ML, Gundry RL, Lindsey ML. Using an Investigative Journalism Approach to Design Mechanistic Experiments in Physiology. Physiology (Bethesda). 2020 Jul 1;35(4):218-219. doi: 10.1152/physiol.00006.2020. PMID: 32490747.
• Bates ML. Respiratory diseases are whole body diseases: opportunities for growth in respiratory physiology. Am J Physiol Lung Cell Mol Physiol. 2021 Sep 1;321(3):L628-L630. doi: 10.1152/ajplung.00326.2021. Epub 2021 Aug 18. PMID: 34405725.

Christopher Benson, MD: 

• Khataei T, Romig-Martin SA, Harding AMS, Radley JJ, Benson CJ. Comparison of murine behavioral and physiologic responses after forced exercise by electrical shock vs. manual prodding. Exp Physiol. 2021 Feb 1. doi: 10.1113/EP089117. Epub ahead of print. PMID: 33527606.

Gail Bishop, PhD: 

• Arkee T, Hostager BS, Houtman JCD, Bishop GA. TRAF3 in T Cells Restrains Negative Regulators of LAT to Promote TCR/CD28 Signaling. J Immunol. 2021 Jun 18:ji2001220. doi: 10.4049/jimmunol.2001220. Epub ahead of print. PMID: 34145060.
• Li H, Hostager BS, Arkee T, Bishop GA. Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR. J Biol Chem. 2021 Aug 18:101097. doi: 10.1016/j.jbc.2021.101097. Epub ahead of print. PMID: 34418432.
• Gurley JM, Gmyrek GB, Hargis EA, Bishop GA, Carr DJJ, Elliott MH. The Chx10-Traf3 Knockout Mouse as a Viable Model to Study Neuronal Immune Regulation. Cells. 2021 Aug 12;10(8):2068. doi: 10.3390/cells10082068. PMID: 34440839; PMCID: PMC8391412.

Sue Bodine, PhD:

• Hughes DC, Turner DC, Baehr LM, Seaborne RA, Viggars M, Jarvis JC, Gorski PP, Stewart CE, Owens DJ, Bodine SC, Sharples AP. Knockdown of the E3 ubiquitin ligase UBR5 and its role in skeletal muscle anabolism. Am J Physiol Cell Physiol. 2021 Jan 1;320(1):C45-C56. doi: 10.1152/ajpcell.00432.2020. Epub 2020 Oct 14. PMID: 33052072.
• Davidyan A, Pathak S, Baar K, Bodine SC. Maintenance of muscle mass in adult male mice is independent of testosterone. PLoS One. 2021 Mar 25;16(3):e0240278. doi: 10.1371/journal.pone.0240278. PMID: 33764986; PMCID: PMC7993603.
• Bodine SC, Brooks HL, Bunnett NW, Coller HA, Frey MR, Joe B, Kleyman TR, Lindsey ML, Marette A, Morty RE, Ramirez JM, Thomsen MB, Yosten GLC. An American Physiological Society cross-journal Call for Papers on "Inter-Organ Communication in Homeostasis and Disease". Am J Physiol Lung Cell Mol Physiol. 2021 May 19. doi: 10.1152/ajplung.00209.2021. Epub ahead of print. PMID: 34010064.
• Baehr LM, Hughes DC, Lynch SA, Van Haver D, Maia TM, Marshall AG, Radoshevich L, Impens F, Waddell DS, Bodine SC. Identification of the MuRF1 Skeletal Muscle Ubiquitylome Through Quantitative Proteomics. Function (Oxf). 2021 May 19;2(4):zqab029. doi: 10.1093/function/zqab029. PMID: 34179788; PMCID: PMC8218097.
• Bruno NE, Nwachukwu JC, Hughes DC, Srinivasan S, Hawkins R, Sturgill D, Hager GL, Hurst S, Sheu SS, Bodine SC, Conkright MD, Nettles KW. Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting. FASEB J. 2021 Dec;35(12):e21999. doi: 10.1096/fj.202100171R. PMID: 34748223.

Trudy Burns, PhD:

• Harville EW, Crook CE, Bazzano LA, Woo JG, Burns TL, Raitakari O, Urbina EM, Venn A, Jacobs DR Jr, Steinberger J, Sinaiko A, Dwyer T, Juonala M; i3C Consortium. Cardiovascular risk factors before and during pregnancy: Does pregnancy unmask or initiate risk? J Obstet Gynaecol Res. 2021 Sep 5. doi: 10.1111/jog.14971. Epub ahead of print. PMID: 34482586.
• Khoury M, Khoury P, Bazzano L, Burns TL, Daniels S, Dwyer T, Ikonen J, Jacobs DR Jr, Juonala M, Kähönen M, Prineas R, Raitakari OT, Steinberger J, Venn A, Viikari J, Woo JG, Sinaiko A, Urbina EM. Prevalence Implications of the 2017 American Academy of Pediatrics Hypertension Guideline and Associations with Adult Hypertension. J Pediatr. 2021 Oct 5:S0022-3476(21)00959-8. doi: 10.1016/j.jpeds.2021.09.056. Epub ahead of print. PMID: 34619113.
• Nuotio J, Laitinen TT, Sinaiko AR, Woo JG, Urbina EM, Jacobs DR Jr, Steinberger J, Prineas RJ, Sabin MA, Burgner DP, Minn H, Burns TL, Bazzano LA, Venn AJ, Viikari JSA, Hutri-Kähönen N, Daniels SR, Raitakari OT, Magnussen CG, Juonala M, Dwyer T. Obesity during childhood is associated with higher cancer mortality rate during adulthood: the i3C Consortium. Int J Obes (Lond). 2021 Nov 2. doi: 10.1038/s41366-021-01000-3. Epub ahead of print. PMID: 34728776.

Lucas Carr, PhD: 

• Thompson HG, Whitaker KM, Young R, Carr LJ. University stakeholders largely unaware and unsupportive of university pouring rights contracts with companies supplying sugar-sweetened beverages. J Am Coll Health. 2021 Mar 24:1-8. doi: 10.1080/07448481.2021.1891920. Epub ahead of print. PMID: 33760721.
• Hosteng KR, Simmering JE, Polgreen LA, Cremer JF, Segre AM, Francis SL, Whitaker KM, Polgreen PM, Carr LJ. Multilevel mHealth Intervention Increases Physical Activity of Older Adults Living in Retirement Community. J Phys Act Health. 2021 May 26:1-7. doi: 10.1123/jpah.2020-0592. Epub ahead of print. PMID: 34039774.
• Gallagher J, Carr LJ. Leisure but Not Occupational Physical Activity and Sedentary Behavior Associated With Better Health. J Occup Environ Med. 2021 Aug 27. doi: 10.1097/JOM.0000000000002365. Epub ahead of print. PMID: 34456325.

Darren Casey, PhD:

• Casey DP, Bock JM. Inorganic nitrate supplementation attenuates conduit artery retrograde and oscillatory shear in older adults. Am J Physiol Heart Circ Physiol. 2021 Jan 15. doi: 10.1152/ajpheart.00843.2020. Epub ahead of print. PMID: 33449848.
• Bock JM, Hughes WE, Ueda K, Feider AJ, Hanada S, Casey DP. Glycemic management is inversely related to skeletal muscle microvascular endothelial function in patients with type 2 diabetes. Physiol Rep. 2021 Mar;9(5):e14764. doi: 10.14814/phy2.14764. PMID: 33660935.
• Carr J, Tremblay JC, Ives SJ, Lyall GK, Baldwin MM, Birch KM, Lee KD, Papadedes DW, King TJ, Gibbons TD, Thomas KN, Hanson BE, Bock JM, Casey DP, Ruediger SL, Bailey TG, Amin SB, Hansen AB, Lawley JS, Williams JS, Cheng JL, MacDonald MJ. Commentaries on Viewpoint: Differential impact of shear rate in the cerebral and systemic circulation: implications for endothelial function. J Appl Physiol (1985). 2021 Apr 1;130(4):1155-1160. doi: 10.1152/japplphysiol.00045.2021. PMID: 33877934.
• Bock JM, Ueda K, Feider AJ, Hanada S, Casey DP. Combined inorganic nitrate/nitrite supplementation blunts α-mediated vasoconstriction during exercise in patients with type 2 diabetes. Nitric Oxide. 2021 Oct 27;118:17-25. doi: 10.1016/j.niox.2021.10.006. Epub ahead of print. PMID: 34718145.

Songhai Chen, PhD: 

• Hu B, Rodriguez JJ, Kakkerla Balaraju A, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican 4 mediates Wnt transport between germ layers via signaling filopodia. J Cell Biol. 2021 Dec 6;220(12):e202009082. doi: 10.1083/jcb.202009082. Epub 2021 Sep 30. PMID: 34591076.

Huxing Cui, PhD:

• Deng Y, Deng G, Grobe JL, Cui H. Hypothalamic GPCR Signaling Pathways in Cardiometabolic Control. Front Physiol. 2021 Jun 28;12:691226. doi: 10.3389/fphys.2021.691226. PMID: 34262481; PMCID: PMC8274634.

Brandon Davies, PhD:

• Spitler KM, Shetty SK, Cushing EM, Sylvers-Davie KL, Davies BSJ. Regulation of plasma triglyceride partitioning by adipose-derived ANGPTL4 in mice. Sci Rep. 2021 Apr 12;11(1):7873. doi: 10.1038/s41598-021-87020-5. PMID: 33846453; PMCID: PMC8041937.
• Sylvers-Davie KL, Davies BSJ. Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8. Am J Physiol Endocrinol Metab. 2021 Aug 2. doi: 10.1152/ajpendo.00195.2021. Epub ahead of print.
• Spitler KM, Shetty SK, Cushing EM, Sylvers-Davie KL, Davies BSJ. Chronic high fat feeding and prolonged fasting in liver-specific ANGPTL4 knockout mice. Am J Physiol Endocrinol Metab. 2021 Aug 16. doi: 10.1152/ajpendo.00144.2021. Epub ahead of print. PMID: 34396783. PMID: 34338039.
• Sylvers-Davie KL, Segura-Roman A, Salvi AM, Schache KJ, Davies BSJ. Angiopoietin-like 3 Inhibition of Endothelial Lipase Is Not Modulated by Angiopoietin-like 8. J Lipid Res. 2021 Aug 27:100112. doi: 10.1016/j.jlr.2021.100112. Epub ahead of print. PMID: 34461133.

Sanjana Dayal, PhD:

• Perepu US, Chambers I, Wahab A, Ten Eyck P, Wu C, Dayal S, Sutamtewagul G, Bailey SR, Rosenstein LJ, Lentz SR. Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID-19: A multi-center, open-label, randomized controlled trial. J Thromb Haemost. 2021 Jul 8. doi: 10.1111/jth.15450. Epub ahead of print. PMID: 34236768.

Kris DeMali, PhD:

• DeWane G, Salvi AM, DeMali KA. Fueling the cytoskeleton - links between cell metabolism and actin remodeling. J Cell Sci. 2021 Feb 8;134(3):jcs248385. doi: 10.1242/jcs.248385. PMID: 33558441; PMCID: PMC7888749.
• Salvi AM, Bays JL, Mackin SR, Mege RM, DeMali KA. Ankyrin G organizes membrane components to promote coupling of cell mechanics and glucose uptake. Nat Cell Biol. 2021 May;23(5):457-466. doi: 10.1038/s41556-021-00677-y. Epub 2021 May 10. PMID: 33972734.
• Antiguas A, DeMali KA, Dunnwald M. Interferon regulatory factor 6 regulates the delivery of E-cadherin to the plasma membrane. J Invest Dermatol. 2021 Jul 23:S0022-202X(21)01497-4. doi: 10.1016/j.jid.2021.06.031. Epub ahead of print. PMID: 34310950.

Joseph Dillon, MB, BCh, BAO:

• Dillon JS, Bushnell D, Laux DE. High-specific-activity 131iodine-metaiodobenzylguanidine for therapy of unresectable pheochromocytoma and paraganglioma. Future Oncol. 2021 Jan 28. doi: 10.2217/fon-2020-0625. Epub ahead of print. PMID: 33506713.
• Scott AT, Tessmann JB, Braun T, Brown B, Breheny PJ, Darbro BW, Bellizzi AM, Dillon JS, O'Dorisio TM, Alderson A, Bennett B, Bernat JA, Metz DC, Howe JR. Presacral neuroendocrine tumors associated with the Currarino syndrome. Am J Med Genet A. 2021 Mar 1. doi: 10.1002/ajmg.a.62145. Epub ahead of print. PMID: 33650152.
• Jha A, Taieb D, Carrasquillo JA, Pryma DA, Patel M, Millo C, de Herder WW, Del Rivero J, Crona J, Shulkin BL, Virgolini I, Chen AP, Mittal BR, Basu S, Dillon JS, Hope TA, Mari Aparici C, Iagaru A, Hicks RJ, Avram AM, Strosberg JR, Civelek AC, Lin FI, Pandit-Taskar N, Pacak K. High-specific-activity 131I-MIBG vs 177Lu-DOTATATE targeted radionuclide therapy for metastatic pheochromocytoma and paraganglioma. Clin Cancer Res. 2021 Mar 8:clincanres.3703.2020. doi: 10.1158/1078-0432.CCR-20-3703. Epub ahead of print. PMID: 33685867.
• Tran CG, Sherman SK, Suraju MO, Nayyar A, Gerke H, Abiad RGE, Chandrasekharan C, Ear PH, O'Dorisio TM, Dillon JS, Bellizzi AM, Howe JR. Management of Duodenal Neuroendocrine Tumors: Surgical versus Endoscopic Mucosal Resection. Ann Surg Oncol. 2021 Sep 13. doi: 10.1245/s10434-021-10774-9. Epub ahead of print. PMID: 34515889.
• Tran CG, Sherman SK, Suraju MO, Nayyar A, Gerke H, El Abiad RG, Chandrasekharan C, Ear PH, O'Dorisio TM, Dillon JS, Bellizzi AM, Howe JR. ASO Visual Abstract: Management of Duodenal Neuroendocrine Tumors-Surgical Versus Endoscopic Mucosal Resection. Ann Surg Oncol. 2021 Oct 20. doi: 10.1245/s10434-021-10852-y. Epub ahead of print. PMID: 34671877.

Ayotunde Dokun, MD, PhD:

• Jalal D, Sanford B, Renner B, Ten Eyck P, Laskowski J, Cooper J, Sun M, Zakharia Y, Spitz D, Dokun A, Attanasio M, Jones K, Thurman JM. Detection of pro angiogenic and inflammatory biomarkers in patients with CKD. Sci Rep. 2021 Apr 22;11(1):8786. doi: 10.1038/s41598-021-87710-0. PMID: 33888746; PMCID: PMC8062467.
• Lamin V, Verry J, Eigner-Bybee I, Fuqua JD, Wong T, Lira VA, Dokun AO. Modulation of miR-29a and ADAM12 Reduces Post-Ischemic Skeletal Muscle Injury and Improves Perfusion Recovery and Skeletal Muscle Function in a Mouse Model of Type 2 Diabetes and Peripheral Artery Disease. Int J Mol Sci. 2021 Dec 31;23(1):429. doi: 10.3390/ijms23010429. PMID: 35008854; PMCID: PMC8745107.

John Engelhardt, PhD: 

• Gibson-Corley KN, Engelhardt JF. Animal Models and Their Role in Understanding the Pathophysiology of Cystic Fibrosis-Associated Gastrointestinal Lesions. Annu Rev Pathol. 2021 Jan 24;16:51-67. doi: 10.1146/annurev-pathol-022420-105133. PMID: 33497264.
• Choi SH, Engelhardt JF. Gene Therapy for Cystic Fibrosis: Lessons Learned and Paths Forward. Mol Ther. 2021 Jan 12:S1525-0016(21)00010-1. doi: 10.1016/j.ymthe.2021.01.010. Epub ahead of print. PMID: 33472034.
• Rotti PG, Evans IA, Zhang Y, Liang B, Cunicelli N, O'Malley Y, Norris AW, Uc A, Engelhardt JF. Lack of CFTR alters the ferret pancreatic ductal epithelial secretome and cellular proteome: Implications for exocrine/endocrine signaling. J Cyst Fibros. 2021 May 17:S1569-1993(21)00120-X. doi: 10.1016/j.jcf.2021.04.010. Epub ahead of print. PMID: 34016558.
• Shen W, Wang Z, Ning K, Cheng F, Engelhardt JF, Yan Z, Qiu J. Hairpin transfer-independent Parvovirus DNA Replication Produces Infectious Virus. J Virol. 2021 Aug 4:JVI0110821. doi: 10.1128/JVI.01108-21. Epub ahead of print. PMID: 34346761.
• Joo NS, Cho HJ, Shinbashi M, Choi JY, Milla CE, Engelhardt JF, Wine JJ. Combined agonists act synergistically to increase mucociliary clearance in a cystic fibrosis airway model. Sci Rep. 2021 Sep 22;11(1):18828. doi: 10.1038/s41598-021-98122-5. PMID: 34552115; PMCID: PMC8458446.

Frank Faraci, PhD: 

• De Silva TM, Modrick ML, Grobe JL, Faraci FM. Activation of the Central Renin-Angiotensin System Causes Local Cerebrovascular Dysfunction. Stroke. 2021 Jun 10:STROKEAHA121034984. doi: 10.1161/STROKEAHA.121.034984. Epub ahead of print. PMID: 34107734.
• Faraci FM. Microvascular changes that stagger the mind. J Clin Invest. 2021 Sep 15;131(18):e153202. doi: 10.1172/JCI153202. PMID: 34523619; PMCID: PMC8439589.
• Claassen JAHR, Thijssen DHJ, Panerai RB, Faraci FM. Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation. Physiol Rev. 2021 Oct 1;101(4):1487-1559. doi: 10.1152/physrev.00022.2020. Epub 2021 Mar 26. PMID: 33769101.

Edward Filardo, PhD: 

• Lu AS, Rouhimoghadam M, Arnatt CK, Filardo EJ, Salem AK. Proteolytic Targeting Chimeras with Specificity for Plasma Membrane and Intracellular Estrogen Receptors. Mol Pharm. 2021 Mar 1;18(3):1455-1469. doi: 10.1021/acs.molpharmaceut.1c00018. Epub 2021 Feb 18. PMID: 33600191.

James Folk, MD:

• Li AS, Velez G, Darbro B, Toral MA, Yang J, Tsang SH, Ferguson PJ, Folk JC, Bassuk AG, Mahajan VB. Whole-Exome Sequencing of Patients With Posterior Segment Uveitis. Am J Ophthalmol. 2021 Jan;221:246-259. doi: 10.1016/j.ajo.2020.07.021. Epub 2020 Jul 21. PMID: 32707200; PMCID: PMC7736069.

Bernd Fritzsch, PhD:

• Jahan I, Kersigo J, Elliott KL, Fritzsch B. Smoothened overexpression causes trochlear motoneurons to reroute and innervate ipsilateral eyes. Cell Tissue Res. 2021 Jan 6. doi: 10.1007/s00441-020-03352-0. Epub ahead of print. PMID: 33409653.
• Xu J, Li J, Zhang T, Jiang H, Ramakrishnan A, Fritzsch B, Shen L, Xu PX. Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2025196118. doi: 10.1073/pnas.2025196118. PMID: 33723076.
• Elliott KL, Kersigo J, Lee JH, Jahan I, Pavlinkova G, Fritzsch B, Yamoah EN. Developmental Changes in Peripherin-eGFP Expression in Spiral Ganglion Neurons. Front Cell Neurosci. 2021 Jun 15;15:678113. doi: 10.3389/fncel.2021.678113. PMID: 34211371; PMCID: PMC8239239.

Sukirth Ganesan, BDS, PhD: 

• Altabtbaei K, Maney P, Ganesan SM, Dabdoub SM, Nagaraja HN, Kumar PS. Anna Karenina and the subgingival microbiome associated with periodontitis. Microbiome. 2021 Apr 30;9(1):97. doi: 10.1186/s40168-021-01056-3. PMID: 33941275; PMCID: PMC8091542.
• Ganesan SM, Vazana S, Stuhr S. Waistline to the gumline: Relationship between obesity and periodontal disease-biological and management considerations. Periodontol 2000. 2021 Oct;87(1):299-314. doi: 10.1111/prd.12390. PMID: 34463987.

Mark Greiner, MD: 

• Skeie JM, Nishimura DY, Wang CL, Schmidt GA, Aldrich BT, Greiner MA. Mitophagy: An Emerging Target in Ocular Pathology. Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):22. doi: 10.1167/iovs.62.3.22. PMID: 33724294.
• Schlötzer-Schrehardt U, Zenkel M, Strunz M, Gießl A, Schondorf H, da Silva H, Schmidt GA, Greiner MA, Okumura N, Koizumi N, Kinoshita S, Tourtas T, Kruse FE. Potential Functional Restoration of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy by ROCK Inhibitor (Ripasudil). Am J Ophthalmol. 2021 Apr;224:185-199. doi: 10.1016/j.ajo.2020.12.006. Epub 2020 Dec 11. PMID: 33316261.
• Naguib YW, Saha S, Skeie JM, Acri T, Ebeid K, Abdel-Rahman S, Kesh S, Schmidt GA, Nishimura DY, Banas JA, Zhu M, Greiner MA, Salem AK. Solubilized ubiquinol for preserving corneal function. Biomaterials. 2021 Aug;275:120842. doi: 10.1016/j.biomaterials.2021.120842. Epub 2021 May 1. PMID: 34087583; PMCID: PMC8325625.

Chad Grueter, PhD: 

• Alghanem AF, Abello J, Maurer JM, Kumar A, Ta CM, Gunasekar SK, Fatima U, Kang C, Xie L, Adeola O, Riker M, Elliot-Hudson M, Minerath RA, Grueter CE, Mullins RF, Stratman AN, Sah R. The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function. Elife. 2021 Feb 25;10:e61313. doi: 10.7554/eLife.61313. Epub ahead of print. PMID: 33629656.
• Scheibe EL, Grueter CE. Mining Metabolomics in Mitral Valve Disease. J Am Heart Assoc. 2021 Apr 23:e020726. doi: 10.1161/JAHA.121.020726. Epub ahead of print. PMID: 33890481.
• Chen X, Zhabyeyev P, Azad AK, Vanhaesebroeck B, Grueter CE, Murray AG, Kassiri Z, Oudit GY. Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction. J Mol Cell Cardiol. 2021 Apr 19;157:17-30. doi: 10.1016/j.yjmcc.2021.04.004. Epub ahead of print. PMID: 33887328.

Isabella Grumbach, MD, PhD:

• Asnani A, Moslehi JJ, Adhikari BB, Baik AH, Beyer AM, de Boer RA, Ghigo A, Grumbach IM, Jain S, Zhu H; American Heart Association Council on Basic Cardiovascular Sciences; Cardio-Oncology Science Subcommittee of Council on Genomic and Precision Medicine and Council on Clinical Cardiology; Council on Peripheral Vascular Disease; and Council on Arteriosclerosis, Thrombosis and Vascular Biology. Preclinical Models of Cancer Therapy-Associated Cardiovascular Toxicity: A Scientific Statement From the American Heart Association. Circ Res. 2021 May 3:RES0000000000000473. doi: 10.1161/RES.0000000000000473. Epub ahead of print. PMID: 33934611.
• Zhang H, Chen ZB, Fredman G, Gomez D, Grumbach IM, Huang NF, Nguyen P, Ouimet M, Sutton NR, Aikawa E. What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award. Arterioscler Thromb Vasc Biol. 2021 Sep 22:ATVBAHA121316558. doi: 10.1161/ATVBAHA.121.316558. Epub ahead of print. PMID: 34547925.

Yumi Imai, MD: 

• Mishra A, Liu S, Promes J, Harata M, Sivitz WI, Fink BD, Bhardwaj G, O'Neill BT, Kang C, Sah R, Strack S, Stephens SB, King TH, Jackson L, Greenberg AS, Anokye-Danso F, Ahima RS, Ankrum JA, Imai Y. Perilipin2 down-regulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria. JCI Insight. 2021 Mar 30:144341. doi: 10.1172/jci.insight.144341. Epub ahead of print. PMID: 33784258.
• Cho J, Tsugawa Y, Imai Y, Imai T. Chorionic gonadotropin stimulates maternal hepatocyte proliferation during pregnancy. Biochem Biophys Res Commun. 2021 Sep 24;579:110-115. doi: 10.1016/j.bbrc.2021.09.039. Epub ahead of print. PMID: 34597993.
• Imai Y. Deciphering regulatory protein activity in human pancreatic islets via reverse engineering of single-cell sequencing data. J Clin Invest. 2021 Dec 15;131(24):e154482. doi: 10.1172/JCI154482. PMID: 34907912; PMCID: PMC8670832.

Kathleen Janz, PhD:

• Chrisman SPD, Mendoza JA, Zhou C, Palermo TM, Gogue-Garcia T, Janz KF, Rivara FP. Pilot Study of Telehealth Delivered Rehabilitative Exercise for Youth With Concussion: The Mobile Subthreshold Exercise Program (MSTEP). Front Pediatr. 2021 May 28;9:645814. doi: 10.3389/fped.2021.645814. PMID: 34123963; PMCID: PMC8193501.
• Hyde ET, Watson KB, Omura JD, Janz KF, Lee SM, Fulton JE, Carlson SA. Surveillance of Meeting the Youth Physical Activity Guideline: Impact of Including Vigorous-Intensity and Bone-Strengthening Activities. Res Q Exerc Sport. 2021 Oct 28:1-6. doi: 10.1080/02701367.2021.1914303. Epub ahead of print. PMID: 34709135.

Modar Kassan, PhD:

• Kassan A, Ait-Aissa K, Kassan M. Hypothalamic miR-204 Induces Alteration of Heart Electrophysiology and Neurogenic Hypertension by Regulating the Sympathetic Nerve Activity: Potential Role of Microbiota. Cureus. 2021 Oct 14;13(10):e18783. doi: 10.7759/cureus.18783. PMID: 34692262; PMCID: PMC8523185.

Randy Kardon, MD, PhD: 

• Reggie SN, Avery RA, Bavinger JC, Jivraj I, Alfaro C, Pistilli M, Kohli AA, Liu GT, Shindler KS, Ross AG, Kardon RH, Sibony PA, Tamhankar M. The sensitivity and specificity of retinal and choroidal folds to distinguish between mild papilloedema and pseudopapilledema. Eye (Lond). 2021 Jan 19. doi: 10.1038/s41433-020-01368-y. Epub ahead of print. PMID: 33469131.

Robert Kerns, PhD:

• Kulkarni CA, Fink BD, Gibbs BE, Chheda PR, Wu M, Sivitz WI, Kerns RJ. A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation. J Med Chem. 2021 Jan 14;64(1):662-676. doi: 10.1021/acs.jmedchem.0c01671. Epub 2021 Jan 4. PMID: 33395531.

Aloysius Klingelhutz, PhD: 

• Kohlmeyer JL, Kaemmer CA, Umesalma S, Gourronc FA, Klingelhutz AJ, Quelle DE. RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner. Int J Mol Sci. 2021 May 20;22(10):5367. doi: 10.3390/ijms22105367. PMID: 34065204; PMCID: PMC8161079.abra

Katie Larson-Ode, MD, MS:

• Merjaneh L, Hasan S, Kasim N, Ode KL. The role of modulators in cystic fibrosis related diabetes. J Clin Transl Endocrinol. 2021 Dec 7;27:100286. doi: 10.1016/j.jcte.2021.100286. PMID: 34917484; PMCID: PMC8668978.

Vitor Lira, PhD: 

• Okutsu M, Yamada M, Tokizawa K, Marui S, Suzuki K, Lira VA, Nagashima K. Regular exercise stimulates endothelium autophagy via IL-1 signaling in ApoE deficient mice. FASEB J. 2021 Jul;35(7):e21698. doi: 10.1096/fj.202002790RR. PMID: 34085350.

Ashutosh Mangalam, PhD: 

• Shahi SK, Ali S, Jaime CM, Guseva NV, Mangalam AK. HLA Class II Polymorphisms Modulate Gut Microbiota and Experimental Autoimmune Encephalomyelitis Phenotype. Immunohorizons. 2021 Aug 11;5(8):627-646. doi: 10.4049/immunohorizons.2100024. PMID: 34380664.
• Simonsen D, Cady N, Zhang C, Shrode RL, McCormick ML, Spitz DR, Chimenti MS, Wang K, Mangalam A, Lehmler HJ. The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice. Toxicol Sci. 2021 Nov 29:kfab142. doi: 10.1093/toxsci/kfab142. Epub ahead of print. PMID: 34850242.

Paul McCray, MD:

• Sun YJ, Velez G, Parsons DE, Li K, Ortiz ME, Sharma S, McCray PB Jr, Bassuk AG, Mahajan VB. Structure-based phylogeny identifies Avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice. J Clin Invest. 2021 Apr 12:147973. doi: 10.1172/JCI147973. Epub ahead of print. PMID: 33844653.
• Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. The NIH Somatic Cell Genome Editing program. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. PMID: 33828315.
• Gallagher T, McCray PB Jr. The first few days of a SARS-CoV-2 infection viewed at single-cell resolution. PLoS Biol. 2021 Apr 26;19(4):e3001217. doi: 10.1371/journal.pbio.3001217. Epub ahead of print. PMID: 33901166.
• Hodos RA, Strub MD, Ramachandran S, Meleshkevitch EA, Boudko DY, Bridges RJ, Dudley JT, McCray PB Jr. Integrative chemogenomic analysis identifies small molecules that partially rescue ΔF508-CFTR for cystic fibrosis. CPT Pharmacometrics Syst Pharmacol. 2021 May;10(5):500-510. doi: 10.1002/psp4.12626. Epub 2021 May 2. PMID: 33934548; PMCID: PMC8129714.
• Sun YJ, Velez G, Parsons DE, Li K, Ortiz ME, Sharma S, McCray PB Jr, Bassuk AG, Mahajan VB. Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice. J Clin Invest. 2021 May 17;131(10):e147973. doi: 10.1172/JCI147973. PMID: 33844653; PMCID: PMC8121520.
• An D, Li K, Rowe DK, Diaz MCH, Griffin EF, Beavis AC, Johnson SK, Padykula I, Jones CA, Briggs K, Li G, Lin Y, Huang J, Mousa J, Brindley M, Sakamoto K, Meyerholz DK, McCray PB Jr, Tompkins SM, He B. Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5-based COVID-19 vaccine. Sci Adv. 2021 Jul 2;7(27):eabi5246. doi: 10.1126/sciadv.abi5246. PMID: 34215591.
• Ortiz ME, Kobayashi T, Imborek K, Alsuhaibani M, Holley S, Trannel A, Marra AR, Etienne W, Jenn KE, Abosi OJ, Meacham H, Sheeler L, Dains A, Kukla ME, McCray PB, Perlman S, Ford B, Diekema DJ, Wellington M, Pezzulo AA, Salinas JL. Molecular epidemiology of large coronavirus disease 2019 (COVID-19) clusters before and after the implementation of routine serial testing at an academic medical center in Iowa, 2020. Infect Control Hosp Epidemiol. 2021 Jun 24:1-3. doi: 10.1017/ice.2021.301. Epub ahead of print. PMID: 34229775; PMCID: PMC8267241.
• Li K, Wohlford-Lenane C, Bartlett JA, McCray PB. Inter-subject variation in ACE2 protein expression in human airway epithelia and its relationship to SARS-CoV-2 infection. J Infect Dis. 2021 Jul 21:jiab383. doi: 10.1093/infdis/jiab383. Epub ahead of print. PMID: 34289058.
• Krishnamurthy S, Traore S, Cooney AL, Brommel CM, Kulhankova K, Sinn PL, Newby GA, Liu DR, McCray PB. Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors. Nucleic Acids Res. 2021 Sep 14:gkab788. doi: 10.1093/nar/gkab788. Epub ahead of print. PMID: 34520545.
• Li K, Meyerholz DK, Bartlett JA, McCray PB Jr. The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19. mBio. 2021 Aug 31;12(4):e0097021. doi: 10.1128/mBio.00970-21. Epub 2021 Aug 3. PMID: 34340553; PMCID: PMC8406266.

Mohamad Mokadem, MD:

• Riedl RA, Burnett CML, Pearson NA, Reho JJ, Mokadem M, Edwards RA, Kindel TL, Kirby JR, Grobe JL. Gut Microbiota Represent a Major Thermogenic Biomass. Function (Oxf). 2021 Apr 15;2(3):zqab019. doi: 10.1093/function/zqab019. PMID: 33939772; PMCID: PMC8055641.
• Chu Y, Tian L, Herz H, Linden B, Morgan DA, Naber MC, Potthoff M, Rahmouni K, Mokadem M. Gastric Bypass Sensitizes Sympathetic and Thermogenic Activity of Brown Adipose Tissue to Cold Exposure. Obes Surg. 2021 Jul 15. doi: 10.1007/s11695-021-05560-1. Epub ahead of print. PMID: 34264434.
• Abu El-Haija M, Ye Y, Chu Y, Herz H, Linden B, Shahi SK, Zarei K, Mangalam AK, Mcelroy SJ, Mokadem M. Toll-like receptor 4 and myeloid differentiation factor 88 are required for gastric bypass-induced metabolic effects. Surg Obes Relat Dis. 2021 Aug 2:S1550-7289(21)00372-5. doi: 10.1016/j.soard.2021.07.019. Epub ahead of print. PMID: 34462225.
• Chu Y, Tian L, Herz H, Linden B, Morgan DA, Naber MC, Potthoff M, Rahmouni K, Mokadem M. Gastric Bypass Sensitizes Sympathetic and Thermogenic Activity of Brown Adipose Tissue to Cold Exposure. Obes Surg. 2021 Oct;31(10):4653-4656. doi: 10.1007/s11695-021-05560-1. Epub 2021 Jul 15. PMID: 34264434; PMCID: PMC8458201.
• Ye Y, Abu El Haija M, Morgan DA, Guo D, Song Y, Frank A, Tian L, Riedl RA, Burnett CML, Gao Z, Zhu Z, Shahi SK, Zarei K, Couvelard A, Poté N, Ribeiro-Parenti L, Bado A, Noureddine L, Bellizzi A, Kievit P, Mangalam AK, Zingman LV, Le Gall M, Grobe JL, Kaplan LM, Clegg D, Rahmouni K, Mokadem M. Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass. Cell Rep. 2020 Oct 27;33(4):108270. doi: 10.1016/j.celrep.2020.108270. PMID: 33113371; PMCID: PMC7660289.
• An Z, Wang H, Mokadem M. Role of the Autonomic Nervous System in Mechanism of Energy and Glucose Regulation Post Bariatric Surgery. Front Neurosci. 2021 Nov 23;15:770690. doi: 10.3389/fnins.2021.770690. PMID: 34887725; PMCID: PMC8649921.
• Herz H, Song Y, Ye Y, Tian L, Linden B, Abu El Haija M, Chu Y, Grobe JL, Lengeling RW, Mokadem M. NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion. Nutrients. 2021 Dec 28;14(1):120. doi: 10.3390/nu14010120. PMID: 35010994; PMCID: PMC8746549.

Brian O'Neill, MD, PhD:

• Cai W, Zhang X, Batista TM, García-Martín R, Softic S, Wang G, Ramirez AK, Konishi M, O'Neill BT, Kim JH, Kim JK, Kahn CR. Peripheral Insulin Regulates a Broad Network of Gene Expression in the Hypothalamus, Hippocampus and Nucleus Accumbens. Diabetes. 2021 May 24:db201119. doi: 10.2337/db20-1119. Epub ahead of print. PMID: 34031123.
• Dougherty SM, Schommer J, Salinas JL, Zilles B, Belding-Schmitt M, Rogers WK, Shibli-Rahhal A, O'Neill BT. Immediate preoperative hyperglycemia correlates with complications in non-cardiac surgical cases. J Clin Anesth. 2021 Jun 16;74:110375. doi: 10.1016/j.jclinane.2021.110375. Epub ahead of print. PMID: 34147016.
• Bhardwaj G, Penniman CM, Jena J, Suarez Beltran PA, Foster C, Poro K, Junck TL, Hinton AO Jr, Souvenir R, Fuqua JD, Morales PE, Bravo-Sagua R, Sivitz WI, Lira VA, Abel ED, O'Neill BT. Insulin and IGF-1 receptors regulate complex-I dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle. J Clin Invest. 2021 Aug 3:146415. doi: 10.1172/JCI146415. Epub ahead of print. PMID: 34343133.
• Homan EP, Brasil Brandao B, Softic S, El Ouaamari A, O'Neill BT, Kulkarni RN, Kim JK, Kahn CR. Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue. J Clin Invest. 2021 Aug 24:143328. doi: 10.1172/JCI143328. Epub ahead of print. PMID: 34428182.

Gary Pierce, PhD: 

• Luehrs RE, Zhang D, Pierce GL, Jacobs DR Jr, Kalhan R, Whitaker KM. Cigarette Smoking and Longitudinal Associations With Blood Pressure: The CARDIA Study. J Am Heart Assoc. 2021 Apr 27:e019566. doi: 10.1161/JAHA.120.019566. Epub ahead of print. PMID: 33902307.
• Stanhewicz AE, Nuckols VR, Pierce GL. Maternal microvascular dysfunction during preeclamptic pregnancy. Clin Sci (Lond). 2021 May 14;135(9):1083-1101. doi: 10.1042/CS20200894. PMID: 33960392.
• Luehrs RE, Moreau KL, Pierce GL, Wamboldt F, Aloia M, Weinberger HD, Make B, Bowler RP, Crapo JD, Meschede K, Kozora E, Moser DJ, Hoth KF. Cognitive Performance is Lower Among Individuals with Overlap Syndrome than with COPD or Obstructive Sleep Apnea Alone: Role of Carotid Artery Stiffness. J Appl Physiol (1985). 2021 May 13. doi: 10.1152/japplphysiol.00477.2020. Epub ahead of print. PMID: 33982592.
• Pierce GL, Roy SJ, Gimblet CJ. The Gut-Arterial Stiffness Axis: Is TMAO a Novel Target to Prevent Age-Related Aortic Stiffening? Hypertension. 2021 Aug;78(2):512-515. doi: 10.1161/HYPERTENSIONAHA.121.17487. Epub 2021 Jul 7. PMID: 34232682; PMCID: PMC8274311.
• Nuckols VR, Stroud AK, Hueser JF, Brandt DS, DuBose LE, Santillan DA, Santillan MK, Pierce GL. 24-Hour Blood Pressure Variability is Associated with Lower Cognitive Performance in Young Women with a Recent History of Preeclampsia. Am J Hypertens. 2021 Jul 19:hpab112. doi: 10.1093/ajh/hpab112. Epub ahead of print. PMID: 34278420.
• Fiedorowicz JG, Dindo L, Ajibewa T, Persons J, Marchman J, Holwerda SW, Abosi OJ, DuBose LE, Wooldridge N, Myers J, Stroud AK, Dubishar K, Liu Z, Pierce GL. One-day acceptance and commitment therapy (ACT) workshop improves anxiety but not vascular function or inflammation in adults with moderate to high anxiety levels in a randomized controlled trial. Gen Hosp Psychiatry. 2021 Sep 28;73:64-70. doi: 10.1016/j.genhosppsych.2021.09.009. Epub ahead of print. PMID: 34619441.

Catherina Pinnaro, MD: 

• O'Malley G, Ebekozien O, Desimone M, Pinnaro CT, Roberts A, Polsky S, Noor N, Aleppo G, Basina M, Tansey M, Steenkamp D, Vendrame F, Lorincz I, Mathias P, Agarwal S, Golden L, Hirsch IB, Levy CJ. COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multicenter Surveillance Study. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e936-e942. doi: 10.1210/clinem/dgaa825. PMID: 33165563; PMCID: PMC7717244.
• Alonso GT, Ebekozien O, Gallagher MP, Rompicherla S, Lyons SK, Choudhary A, Majidi S, Pinnaro CT, Balachandar S, Gangat M, Curda Roberts AJ, Marks BE, Creo A, Sanchez J, Seeherunvong T, Jimenez-Vega J, Patel NS, Wood JR, Gabriel L, Sumpter KM, Wilkes M, Rapaport R, Cymbaluk A, Wong JC, Sanda S, Albanese-O'neill A. Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes. J Diabetes. 2021 Apr 14. doi: 10.1111/1753-0407.13184. Epub ahead of print. PMID: 33855813.
• Subramani S, Bellizzi AM, Borcherding N, Kao SC, Dillon J, Howe J, Norris AW, Tansey MJ, Pinnaro CT. Hypoglycemia secondary to insulinoma masking the onset of type 1 diabetes in an adolescent. Clin Case Rep. 2021 Sep 24;9(9):e04868. doi: 10.1002/ccr3.4868. PMID: 34594558; PMCID: PMC8462061.
• Palmer BA, Soltys K, Zimmerman MB, Norris AW, Tsalikian E, Tansey MJ, Pinnaro CT. Diabetes Device Downloading: Benefits and Barriers Among Youth With Type 1 Diabetes. J Diabetes Sci Technol. 2021 Nov 22:19322968211059537. doi: 10.1177/19322968211059537. Epub ahead of print. PMID: 34809477.

Robert Piper, PhD:

• Tseng CC, Dean S, Davies BA, Azmi IF, Pashkova N, Payne JA, Staffenhagen J, West M, Piper RC, Odorizzi G, Katzmann DJ. Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis. J Cell Biol. 2021 Aug 2;220(8):e202102070. doi: 10.1083/jcb.202102070. Epub 2021 Jun 23. PMID: 34160559.
• Pashkova N, Yu L, Schnicker NJ, Tseng CC, Gakhar L, Katzmann DJ, Piper RC. Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase. Mol Biol Cell. 2021 Sep 29:mbcE21040219. doi: 10.1091/mbc.E21-04-0219. Epub ahead of print. PMID: 34586919.

Phillip Polgreen, PhD:

• Beekmann SE, Babcock HM, Rasnake MS, Talbot TR, Polgreen PM. COVID-19 Vaccination Preparedness Policies in U.S. Hospitals. Infect Control Hosp Epidemiol. 2021 Apr 19:1-13. doi: 10.1017/ice.2021.181. Epub ahead of print. PMID: 33866989
• Francis SL, Simmering JE, Polgreen LA, Evans NJ, Hosteng KR, Carr LJ, Cremer JF, Coe S, Cavanaugh JE, Segre AM, Polgreen PM. Gamifying accelerometer use increases physical activity levels of individuals pre-disposed to type II diabetes. Prev Med Rep. 2021 May 30;23:101426. doi: 10.1016/j.pmedr.2021.101426. PMID: 34178586; PMCID: PMC8209749.

Matthew Potthoff, PhD: 

• Flippo KH, Potthoff MJ. Metabolic Messengers: FGF21. Nat Metab. 2021 Mar;3(3):309-317. doi: 10.1038/s42255-021-00354-2. Epub 2021 Mar 18. PMID: 33758421.
• Reilly SM, Abu-Odeh M, Ameka M, DeLuca JH, Naber MC, Dadpey B, Ebadat N, Gomez AV, Peng X, Poirier B, Walk E, Potthoff MJ, Saltiel AR. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. J Clin Invest. 2021 Apr 6:145546. doi: 10.1172/JCI145546. Epub ahead of print. PMID: 33822771.
• Sostre-Colón J, Uehara K, Garcia Whitlock AE, Gavin MJ, Ishibashi J, Potthoff MJ, Seale P, Titchenell PM. Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms. Cell Rep. 2021 May 18;35(7):109128. doi: 10.1016/j.celrep.2021.109128. PMID: 34010646.
• Claflin KE, Flippo KH, Sullivan AI, Naber MC, Zhou B, Neff TJ, Jensen-Cody SO, Potthoff MJ. Conditional gene targeting using UCP1-Cre mice directly targets the central nervous system beyond thermogenic adipose tissues. Mol Metab. 2022 Jan;55:101405. doi: 10.1016/j.molmet.2021.101405. Epub 2021 Nov 26. PMID: 34844020; PMCID: PMC8683614.

Kamal Rahmouni, PhD: 

• Rouabhi M, Guo DF, Morgan DA, Zhu Z, López M, Zingman L, Grobe JL, Rahmouni K. BBSome Ablation in SF1 Neurons Causes Obesity without the Comorbidities. Mol Metab. 2021 Mar 12:101211. doi: 10.1016/j.molmet.2021.101211. Epub ahead of print. PMID: 33722691.
• Gruber T, Pan C, Contreras RE, Wiedemann T, Morgan DA, Skowronski AA, Lefort S, De Bernardis Murat C, Le Thuc O, Legutko B, Ruiz-Ojeda FJ, Fuente-Fernández M, García-Villalón AL, González-Hedström D, Huber M, Szigeti-Buck K, Müller TD, Ussar S, Pfluger P, Woods SC, Ertürk A, LeDuc CA, Rahmouni K, Granado M, Horvath TL, Tschöp MH, García-Cáceres C. Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension. Cell Metab. 2021 Apr 30:S1550-4131(21)00173-X. doi: 10.1016/j.cmet.2021.04.007. Epub ahead of print. PMID: 33951475.
• Reho JJ, Guo DF, Beyer AM, Wegman-Points L, Pierce GL, Rahmouni K. Vascular Effects of Disrupting Endothelial mTORC1 (Mechanistic Target of Rapamycin Complex 1) Signaling in Obesity. Am J Physiol Regul Integr Comp Physiol. 2021 Jun 30. doi: 10.1152/ajpregu.00113.2021. Epub ahead of print. PMID: 34189960.
• Jiang J, Reho JJ, Bhattarai S, Cherascu I, Hedberg-Buenz A, Meyer KJ, Tayyari F, Rauckhorst AJ, Guo DF, Morgan DA, Taylor EB, Anderson MG, Drack AV, Rahmouni K. Endothelial BBSome is Essential for Vascular, Metabolic, and Retinal Functions. Mol Metab. 2021 Jul 22:101308. doi: 10.1016/j.molmet.2021.101308. Epub ahead of print. PMID: 34303879.
• Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC, Hausen AC. Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun. 2021 Sep 2;12(1):5249. doi: 10.1038/s41467-021-25380-2. PMID: 34475397.
• Milbank E, Dragano NRV, González-García I, Garcia MR, Rivas-Limeres V, Perdomo L, Hilairet G, Ruiz-Pino F, Mallegol P, Morgan DA, Iglesias-Rey R, Contreras C, Vergori L, Cuñarro J, Porteiro B, Gavaldà-Navarro A, Oelkrug R, Vidal A, Roa J, Sobrino T, Villarroya F, Diéguez C, Nogueiras R, García-Cáceres C, Tena-Sempere M, Mittag J, Carmen Martínez M, Rahmouni K, Andriantsitohaina R, López M. Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation. Nat Metab. 2021 Oct;3(10):1415-1431. doi: 10.1038/s42255-021-00467-8. Epub 2021 Oct 21. PMID: 34675439.

Jennifer Robinson, MD: 

• Robinson JG. The neuropsychology of statin intolerance. Nat Rev Cardiol. 2021 Jan 6. doi: 10.1038/s41569-020-00502-3. Epub ahead of print. PMID: 33408360.
• Navar AM, Wang TY, Li S, Mi X, Li Z, Robinson JG, Virani SS, Peterson ED. Patient-Perceived Versus Actual Risk of Cardiovascular Disease and Associated Willingness to Consider and Use Prevention Therapy. Circ Cardiovasc Qual Outcomes. 2021 Jan;14(1):e006548. doi: 10.1161/CIRCOUTCOMES.120.006548. Epub 2021 Jan 13. PMID: 33435730.
• Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindström J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q; Fatty Acids and Outcomes Research Consortium (FORCE). n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies. Diabetes Care. 2021 Mar 3:dc202426. doi: 10.2337/dc20-2426. Epub ahead of print. PMID: 33658295.
• Harris WS, Tintle NL, Manson JE, Metherel AH, Robinson JG. Effects of menopausal hormone therapy on erythrocyte n-3 and n-6 PUFA concentrations in the Women's Health Initiative randomized trial. Am J Clin Nutr. 2021 Mar 12:nqaa443. doi: 10.1093/ajcn/nqaa443. Epub ahead of print. PMID: 33710263.
• Lowenstern A, Li S, Navar AM, Virani SS, Roger VL, Robinson JG, Goldberg AC, Kampman W, Peterson ED, Wang TY. Patient perceptions and use of non-statin lipid lowering therapy among patients with or at risk for atherosclerotic cardiovascular disease: Insights from the PALM registry. Clin Cardiol. 2021 May 18. doi: 10.1002/clc.23625. Epub ahead of print. PMID: 34008247.
• Wild RA, Hovey KM, Andrews C, Robinson JG, Kaunitz AM, Manson JE, Crandall CJ, Paragallo R, Shufelt C, Merz CNB. Cardiovascular disease (CVD) risk scores, age, or years since menopause to predict cardiovascular disease in the Women's Health Initiative. Menopause. 2021 May 3;28(6):610-618. doi: 10.1097/GME.0000000000001753. PMID: 33950030; PMCID: PMC8141005.

Robert Roghair, MD:

• Vass RA, Kiss G, Bell EF, Roghair RD, Miseta A, Bódis J, Funke S, Ertl T. Breast Milk for Term and Preterm Infants-Own Mother's Milk or Donor Milk? Nutrients. 2021 Jan 28;13(2):424. doi: 10.3390/nu13020424. PMID: 33525560.

Stephen Russell, MD:

• Al-Khersan H, Russell JF, Lazzarini TA, Scott NL, Hinkle JW, Patel NA, Yannuzzi NA, Fowler BJ, Hussain RM, Barikian A, Sridhar J, Russell SR, Haddock LJ, Smiddy WE, Hariprasad SM, Shi Y, Wang L, Feuer W, Gregori G, Rosenfeld PJ. Comparison Between Graders in Detection of Diabetic Neovascularization With Swept Source Optical Coherence Tomography Angiography and Fluorescein Angiography. Am J Ophthalmol. 2021 Apr;224:292-300. doi: 10.1016/j.ajo.2020.11.020. Epub 2020 Dec 11. PMID: 33309812; PMCID: PMC8058287.

Julien Sebag, PhD: 

• Verdinez JA, Sebag JA. Role of N-Linked Glycosylation in PKR2 Trafficking and Signaling. Front Neurosci. 2021 Aug 13;15:730417. doi: 10.3389/fnins.2021.730417. PMID: 34483834; PMCID: PMC8414166

Alberto Segre, PhD: 

• Jang H, Polgreen PM, Segre AM, Pemmaraju SV. COVID-19 modeling and non-pharmaceutical interventions in an outpatient dialysis unit. PLoS Comput Biol. 2021 Jul 8;17(7):e1009177. doi: 10.1371/journal.pcbi.1009177. PMID: 34237062.

William Sivitz, MD:

• Fink BD, Yu L, Coppey L, Obrosov A, Shevalye H, Kerns RJ, Yorek MA, Sivitz WI. Effect of mitoquinone on liver metabolism and steatosis in obese and diabetic rats. Pharmacol Res Perspect. 2021 Feb;9(1):e00701. doi: 10.1002/prp2.701. PMID: 33547885.
• Yu L, Fink BD, Sivitz WI. Simultaneous Quantification of Mitochondrial ATP and ROS Production Using ATP Energy Clamp Methodology. Methods Mol Biol. 2021;2276:271-283. doi: 10.1007/978-1-0716-1266-8_21. PMID: 34060049.

Linda Snetselaar, PhD:

• Luo J, Chen X, Tindle H, Shadyab AH, Saquib N, Hale L, Garcia L, Springfield S, Liu B, Nassir R, Snetselaar L, Hendryx M. Do health behaviors mediate associations between personality traits and diabetes incidence? Ann Epidemiol. 2021 Jan;53:7-13.e2. doi: 10.1016/j.annepidem.2020.08.007. Epub 2020 Aug 15. PMID: 32805399.
• Weaver CM, Fukagawa NK, Liska D, Mattes RD, Matuszek G, Nieves JW, Shapses SA, Snetselaar LG. Perspective: US Documentation and Regulation of Human Nutrition Randomized Controlled Trials. Adv Nutr. 2021 Feb 1;12(1):21-45. doi: 10.1093/advances/nmaa118. PMID: 33200185; PMCID: PMC7850145.
• Bailey RL, Ard JD, Davis TA, Naimi TS, Schneeman BO, Stang JS, Dewey KG, Donovan SM, Novotny R, Snetselaar LG, de Jesus J, Casavale KO, Pannucci T, Stoody EE. A Proposed Framework for Identifying Nutrients and Food Components of Public Health Relevance in the Dietary Guidelines for Americans. J Nutr. 2021 Mar 9:nxaa459. doi: 10.1093/jn/nxaa459. Epub ahead of print. PMID: 33693925.
• Greenberg JA, Jiang X, Tinker LF, Snetselaar LG, Saquib N, Shadyab AH. Eggs, dietary cholesterol, choline, betaine, and diabetes risk in the Women's Health Initiative: a prospective analysis. Am J Clin Nutr. 2021 Apr 7:nqab036. doi: 10.1093/ajcn/nqab036. Epub ahead of print. PMID: 33829251.
• Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Risérus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE). Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. Nat Commun. 2021 Apr 22;12(1):2329. doi: 10.1038/s41467-021-22370-2. PMID: 33888689.
• Pan K, Aragaki AK, Neuhouser ML, Simon MS, Luo J, Caan B, Snetselaar L, Mortimer JE, Manson JE, Kroenke C, Lane D, Reding K, Rohan TE, Chlebowski RT. Low-fat dietary pattern and breast cancer mortality by metabolic syndrome components: a secondary analysis of the Women's Health Initiative (WHI) randomised trial. Br J Cancer. 2021 May 18. doi: 10.1038/s41416-021-01379-w. Epub ahead of print. PMID: 34006923.
• Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Risérus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE). Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. Nat Commun. 2021 Apr 22;12(1):2329. doi: 10.1038/s41467-021-22370-2. PMID: 33888689; PMCID: PMC8062567.
• Chen GC, Arthur R, Mossavar-Rahmani Y, Xue X, Haring B, Shadyab AH, Allison MA, Liu S, Tinker LF, Saquib N, Coday M, Shikany JM, Neuhouser ML, Snetselaar LG, Van Horn L, Rohan TE, Wassertheil-Smoller S, Kaplan RC, Qi Q. Adherence to Recommended Eating Patterns Is Associated With Lower Risk of Peripheral Arterial Disease: Results From the Women's Health Initiative. Hypertension. 2021 Aug;78(2):447-455. doi: 10.1161/HYPERTENSIONAHA.121.17432. Epub 2021 Jun 28. PMID: 34176290.
• Haslam DE, Peloso GM, Guirette M, Imamura F, Bartz TM, Pitsillides AN, Wang CA, Li-Gao R, Westra JM, Pitkänen N, Young KL, Graff M, Wood AC, Braun KVE, Luan J, Kähönen M, Kiefte-de Jong JC, Ghanbari M, Tintle N, Lemaitre RN, Mook-Kanamori DO, North K, Helminen M, Mossavar-Rahmani Y, Snetselaar L, Martin LW, Viikari JS, Oddy WH, Pennell CE, Rosendaal FR, Ikram MA, Uitterlinden AG, Psaty BM, Mozaffarian D, Rotter JI, Taylor KD, Lehtimäki T, Raitakari OT, Livingston KA, Voortman T, Forouhi NG, Wareham NJ, de Mutsert R, Rich SS, Manson JE, Mora S, Ridker PM, Merino J, Meigs JB, Dashti HS, Chasman DI, Lichtenstein AH, Smith CE, Dupuis J, Herman MA, McKeown NM. Sugar-sweetened Beverage Consumption May Modify Associations between Genetic Variants in the CHREBP Locus and HDL-C and TG Concentrations. Circ Genom Precis Med. 2021 Jul 16. doi: 10.1161/CIRCGEN.120.003288. Epub ahead of print. PMID: 34270325.
• Glenn AJ, Lo K, Jenkins DJA, Boucher BA, Hanley AJ, Kendall CWC, Manson JE, Vitolins MZ, Snetselaar LG, Liu S, Sievenpiper JL. Relationship Between a Plant-Based Dietary Portfolio and Risk of Cardiovascular Disease: Findings From the Women's Health Initiative Prospective Cohort Study. J Am Heart Assoc. 2021 Aug 17;10(16):e021515. doi: 10.1161/JAHA.121.021515. Epub 2021 Aug 4. PMID: 34346245.
• Nevins JEH, Donovan SM, Snetselaar L, Dewey KG, Novotny R, Stang J, Taveras EM, Kleinman RE, Bailey RL, Raghavan R, Scinto-Madonich SR, Venkatramanan S, Butera G, Terry N, Altman J, Adler M, Obbagy JE, Stoody EE, de Jesus J. Omega-3 Fatty Acid Dietary Supplements Consumed During Pregnancy and Lactation and Child Neurodevelopment: A Systematic Review. J Nutr. 2021 Aug 12:nxab238. doi: 10.1093/jn/nxab238. Epub ahead of print. PMID: 34383914.
• Schneeman BO, Ard JD, Boushey CJ, Bailey RL, Novotny R, Snetselaar LG, de Jesus JM, Stoody EE. Perspective: Impact of the National Academy of Sciences, Engineering, and Medicine Report on the Process for the 2020 Dietary Guidelines Advisory Committee. Adv Nutr. 2021 Jul 30;12(4):1051-1057. doi: 10.1093/advances/nmab023. PMID: 33734285; PMCID: PMC8382515.
• English LK, Ard JD, Bailey RL, Bates M, Bazzano LA, Boushey CJ, Brown C, Butera G, Callahan EH, de Jesus J, Mattes RD, Mayer-Davis EJ, Novotny R, Obbagy JE, Rahavi EB, Sabate J, Snetselaar LG, Stoody EE, Van Horn LV, Venkatramanan S, Heymsfield SB. Evaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review. JAMA Netw Open. 2021 Aug 2;4(8):e2122277. doi: 10.1001/jamanetworkopen.2021.22277. PMID: 34463743.
• Omofuma OO, Peterson LL, Turner DP, Merchant AT, Zhang J, Thomson CA, Neuhouser ML, Snetselaar LG, Caan BJ, Shadyab AH, Saquib N, Banack HR, Uribarri J, Steck SE. Dietary Advanced Glycation End-Products and Mortality after Breast Cancer in the Women's Health Initiative. Cancer Epidemiol Biomarkers Prev. 2021 Sep 28. doi: 10.1158/1055-9965.EPI-21-0610. Epub ahead of print. PMID: 34583965.
• Bailey RL, Stang JS, Davis TA, Naimi TS, Schneeman BO, Dewey KG, Donovan SM, Novotny R, Kleinman RE, Taveras EM, Bazzano L, Snetselaar LG, de Jesus J, Casavale KO, Stoody EE, Goldman JD, Moshfegh AJ, Rhodes DG, Herrick KA, Koegel K, Perrine CG, Pannucci T. Dietary and complementary feeding practices of U.S. infants, 6-12 months: A narrative review of the Federal nutrition monitoring data. J Acad Nutr Diet. 2021 Oct 21:S2212-2672(21)01384-8. doi: 10.1016/j.jand.2021.10.017. Epub ahead of print. PMID: 34688966.
• Titcomb TJ, Brooks L, Smith KL, Ten Eyck P, Rubenstein LM, Wahls TL, Snetselaar LG. Change in Micronutrient Intake among People with Relapsing-Remitting Multiple Sclerosis Adapting the Swank and Wahls Diets: An Analysis of Weighed Food Records. Nutrients. 2021 Oct 5;13(10):3507. doi: 10.3390/nu13103507. PMID: 34684508; PMCID: PMC8540533.

Elliott Sohn, MD:

• Ricca AM, Han IC, Sohn EH. Stargardt disease masquerades. Curr Opin Ophthalmol. 2021 Feb 26. doi: 10.1097/ICU.0000000000000750. Epub ahead of print. PMID: 33653979.
• Pouw AE, Greiner MA, Coussa RG, Jiao C, Han IC, Skeie JM, Fingert JH, Mullins RF, Sohn EH. Cell-Matrix Interactions in the Eye: From Cornea to Choroid. Cells. 2021 Mar 20;10(3):687. doi: 10.3390/cells10030687. PMID: 33804633; PMCID: PMC8003714.
• Tan TE, Chan HW, Singh M, Wong TY, Pulido JS, Michaelides M, Sohn EH, Ting D. Artificial intelligence for diagnosis of inherited retinal disease: an exciting opportunity and one step forward. Br J Ophthalmol. 2021 May 24:bjophthalmol-2021-319365. doi: 10.1136/bjophthalmol-2021-319365. Epub ahead of print. PMID: 34031045.
• Lee K, Warren AK, Abràmoff MD, Wahle A, Whitmore SS, Han IC, Fingert JH, Scheetz TE, Mullins RF, Sonka M, Sohn EH. Automated Segmentation of Choroidal Layers from 3-Dimensional Macular Optical Coherence Tomography Scans. J Neurosci Methods. 2021 Jun 19:109267. doi: 10.1016/j.jneumeth.2021.109267. Epub ahead of print. PMID: 34157370.

Milan Sonka, PhD:

• van der Plas E, Gutmann L, Thedens D, Shields RK, Langbehn K, Guo Z, Sonka M, Nopoulos P. Quantitative muscle MRI as a sensitive marker of early muscle pathology in myotonic dystrophy type 1. Muscle Nerve. 2021 Apr;63(4):553-562. doi: 10.1002/mus.27174. Epub 2021 Feb 5. PMID: 33462896.
• Lopez JJ, Sonka M. Is Deep Learning Coming to Guide Your Coronary Intervention? JACC Cardiovasc Interv. 2021 Apr 7:S1936-8798(21)00341-1. doi: 10.1016/j.jcin.2021.02.029. Epub ahead of print. PMID: 33865732.
• Vecchi JT, Mullan S, Lopez JA, Hansen MR, Sonka M, Lee A. NeuriteNet: A convolutional neural network for assessing morpholograhical parameters of neurite growth. J Neurosci Methods. 2021 Sep 2;363:109349. doi: 10.1016/j.jneumeth.2021.109349. Epub ahead of print. PMID: 34480956.
• Bathla G, Liu Y, Zhang H, Sonka M, Derdeyn C. Computed Tomography Perfusion-Based Prediction of Core Infarct and Tissue at Risk: Can Artificial Intelligence Help Reduce Radiation Exposure? Stroke. 2021 Oct 21:STROKEAHA121034266. doi: 10.1161/STROKEAHA.121.034266. Epub ahead of print. PMID: 34670412.

Long-Sheng Song, MD: 

• Romer SH, Metzger S, Peraza K, Wright MC, Jobe DS, Song LS, Rich MM, Foy BD, Talmadge RJ, Voss AA. A mouse model of Huntington's disease shows altered ultrastructure of transverse tubules in skeletal muscle fibers. J Gen Physiol. 2021 Apr 5;153(4):e202012637. doi: 10.1085/jgp.202012637. PMID: 33683318.
• Wang J, Ciampa G, Zheng D, Shi Q, Chen B, Abel ED, Peng T, Hall D, Song LS. Calpain-2 Specifically Cleaves Junctophilin-2 at the Same Site as Calpain-1 but with Less Efficacy. Biochem J. 2021 Sep 15:BCJ20210629. doi: 10.1042/BCJ20210629. Epub ahead of print. PMID: 34524407.

Douglas Spitz, PhD:

• Ma DC, Anderson CM, Rodman SN, Buranasudja V, McCormick ML, Davis A, Loth E, Bodeker KL, Ahmann L, Parkhurst JR, Sun W, Follmer KR, Simons AL, Buatt JM, Spitz DR, Fath MA, Allen BG. Ketogenic Diet with Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma: Preclinical and Phase 1 Trial Results. Radiat Res. 2021 Jun 4. doi: 10.1667/RADE-20-00150.1. Epub ahead of print. PMID: 34087943.
• Petronek MS, Stolwijk JM, Murray SD, Steinbach EJ, Zakharia Y, Buettner GR, Spitz DR, Allen BG. Utilization of redox modulating small molecules that selectively act as pro-oxidants in cancer cells to open a therapeutic window for improving cancer therapy. Redox Biol. 2021 Jun;42:101864. doi: 10.1016/j.redox.2021.101864. Epub 2021 Jan 16. PMID: 33485837; PMCID: PMC8113052.
• Sishc BJ, Ding L, Nam TK, Heer CD, Rodman SN, Schoenfeld JD, Fath MA, Saha D, Pulliam CF, Langen B, Beardsley RA, Riley DP, Keene JL, Spitz DR, Story MD. Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide. Sci Transl Med. 2021 May 12;13(593):eabb3768. doi: 10.1126/scitranslmed.abb3768. PMID: 33980575.
• Mapuskar KA, Steinbach EJ, Zaher A, Riley DP, Beardsley RA, Keene JL, Holmlund JT, Anderson CM, Zepeda-Orozco D, Buatti JM, Spitz DR, Allen BG. Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury. Antioxidants (Basel). 2021 Aug 24;10(9):1329. doi: 10.3390/antiox10091329. PMID: 34572961; PMCID: PMC8469643.
• Mehdi Z, Petronek MS, Stolwijk JM, Mapuskar KA, Kalen AL, Buettner GR, Cullen JJ, Spitz DR, Buatti JM, Allen BG. Utilization of Pharmacological Ascorbate to Enhance Hydrogen Peroxide-Mediated Radiosensitivity in Cancer Therapy. Int J Mol Sci. 2021 Oct 8;22(19):10880. doi: 10.3390/ijms221910880. PMID: 34639220; PMCID: PMC8509557.

Anna Stanhewicz, PhD:

• Dillon GA, Stanhewicz AE, Serviente C, Greaney JL, Alexander LM. Hydrogen sulfide-dependent microvascular vasodilation is improved following chronic sulfhydryl-donating antihypertensive pharmacotherapy in hypertensive adults. Am J Physiol Heart Circ Physiol. 2021 Sep 3. doi: 10.1152/ajpheart.00404.2021. Epub ahead of print. PMID: 34477463.

Samuel Stephens, PhD:

• Bauchle CJ, Rohli KE, Boyer CK, Pal V, Rocheleau JV, Liu S, Imai Y, Taylor EB, Stephens SB. Mitochondrial efflux of citrate and isocitrate is fully dispensable for glucose-stimulated insulin secretion and pancreatic islet β-cell function. Diabetes. 2021 May 26:db210037. doi: 10.2337/db21-0037. Epub ahead of print. PMID: 34039628.
• Maharjan CK, Umesalma S, Kaemmer CA, Muniz VP, Bauchle C, Mott SL, Zamba KD, Breheny P, Leidinger MR, Darbro BW, Stephens SB, Meyerholz DK, Quelle DE. RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo. Biomedicines. 2021 Jun 2;9(6):633. doi: 10.3390/biomedicines9060633. PMID: 34199469; PMCID: PMC8228095.
• Bauchle CJ, Rohli KE, Boyer CK, Pal V, Rocheleau JV, Liu S, Imai Y, Taylor EB, Stephens SB. Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function. Diabetes. 2021 Aug;70(8):1717-1728. doi: 10.2337/db21-0037. Epub 2021 May 26. PMID: 34039628; PMCID: PMC8385611

Stefan Strack, PhD:

• Sandal P, Jong CJ, Merrill RA, Song J, Strack S. Protein phosphatase 2A - structure, function and role in neurodevelopmental disorders. J Cell Sci. 2021 Jul 1;134(13):jcs248187. doi: 10.1242/jcs.248187. Epub 2021 Jul 6. PMID: 34228795.

David Stoltz, MD, PhD: 

• Fischer AJ, Singh SB, LaMarche MM, Maakestad LJ, Kienenberger ZE, Peña TA, Stoltz DA, Limoli DH. Sustained Coinfections with Staphylococcus aureus and Pseudomonas aeruginosa in Cystic Fibrosis. Am J Respir Crit Care Med. 2021 Feb 1;203(3):328-338. doi: 10.1164/rccm.202004-1322OC. PMID: 32750253; PMCID: PMC7874317.
• Bouzek DC, Abou Alaiwa MH, Adam RJ, Pezzulo AA, Reznikov LR, Cook DP, Aguilar Pescozo MI, Ten Eyck P, Wu C, Gross TJ, Hornick DB, Hoffman EA, Meyerholz DK, Stoltz DA. Early Lung Disease Exhibits Bacterial-Dependent and -Independent Abnormalities in Cystic Fibrosis Pigs. Am J Respir Crit Care Med. 2021 Jun 25. doi: 10.1164/rccm.202102-0451OC. Epub ahead of print. PMID: 34170795.
• Zarei K, Meyerholz DK, Stoltz DA. Early intrahepatic duct defects in a cystic fibrosis porcine model. Physiol Rep. 2021 Jul;9(14):e14978. doi: 10.14814/phy2.14978. PMID: 34288572; PMCID: PMC8290831.
• Li X, Villacreses R, Thornell IM, Noriega J, Mather S, Brommel CM, Lu L, Zabner A, Ehler A, Meyerholz DK, Stoltz DA, Zabner J. V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2021 Aug;65(2):146-156. doi: 10.1165/rcmb.2020-0349OC. PMID: 33789071; PMCID: PMC8399571.
• Holliday ZM, Launspach JL, Durairaj L, Singh PK, Zabner J, Stoltz DA. Effects of Tham Nasal Alkalinization on Airway Microbial Communities: A Pilot Study in Non-CF and CF Adults. Ann Otol Rhinol Laryngol. 2021 Oct 21:34894211051814. doi: 10.1177/00034894211051814. Epub ahead of print. PMID: 34674574.

Michael Tansey, MD: 

• Mauras N, Buckingham B, White NH, Tsalikian E, Weinzimer SA, Jo B, Cato A, Fox LA, Aye T, Arbelaez AM, Hershey T, Tansey M, Tamborlane W, Foland-Ross LC, Shen H, Englert K, Mazaika P, Marzelli M, Reiss AL; Diabetes Research in Children Network (DirecNet). Impact of Type 1 Diabetes in the Developing Brain in Children: A Longitudinal Study. Diabetes Care. 2021 Feb 10:dc202125. doi: 10.2337/dc20-2125. Epub ahead of print. PMID: 33568403.

Eric Taylor, PhD:

• Petrie MA, Taylor EB, Suneja M, Shields RK. Genomic and Epigenomic Evaluation of Electrically Induced Exercise in People with Spinal Cord Injury: Application to Precision Rehabilitation. Phys Ther. 2021 Nov 1:pzab243. doi: 10.1093/ptj/pzab243. Epub ahead of print. PMID: 34718779.

Eva Tslaikian, MD:

• Gitelman SE, Bundy BN, Ferrannini E, Lim N, Blanchfield JL, DiMeglio LA, Felner EI, Gaglia JL, Gottlieb PA, Long SA, Mari A, Mirmira RG, Raskin P, Sanda S, Tsalikian E, Wentworth JM, Willi SM, Krischer JP, Bluestone JA; Gleevec Trial Study Group. Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol. 2021 Jun 29:S2213-8587(21)00139-X. doi: 10.1016/S2213-8587(21)00139-X. Epub ahead of print. PMID: 34214479.

Aliye Uc, MD:

• Yi Y, Sun X, Liang B, He N, Gibson-Corley KN, Norris AW, Engelhardt JF, Uc A. Acute pancreatitis-induced islet dysfunction in ferrets. Pancreatology. 2021 May 11:S1424-3903(21)00147-2. doi: 10.1016/j.pan.2021.04.008. Epub ahead of print. PMID: 33994067.
• Dike CR, Cress G, Fishman DS, Gonska T, Ooi CY, Perito ER, Troendle D, Tsai CM, Lowe ME, Uc A. Vascular Complications in Pediatric Pancreatitis: A Case Series. J Pediatr Gastroenterol Nutr. 2021 Jun 29. doi: 10.1097/MPG.0000000000003218. Epub ahead of print. PMID: 34224489.

Yuriy Usachev, PhD:

• Rysted JE, Lin Z, Walters GC, Rauckhorst AJ, Noterman M, Liu G, Taylor EB, Strack S, Usachev YM. Distinct properties of Ca2+ efflux from brain, heart and liver mitochondria: The effects of Na+, Li+ and the mitochondrial Na+/Ca2+ exchange inhibitor CGP37157. Cell Calcium. 2021 Feb 22;96:102382. doi: 10.1016/j.ceca.2021.102382. Epub ahead of print. PMID: 33684833.
• Warwick CA, Keyes AL, Woodruff TM, Usachev YM. The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain. J Biol Chem. 2021 Aug 16:101085. doi: 10.1016/j.jbc.2021.101085. Epub ahead of print. PMID: 34411562.

Michael Welsh, MD:

• Simmering JE, Welsh MJ, Liu L, Narayanan NS, Pottegård A. Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease. JAMA Neurol. 2021 Feb 1. doi: 10.1001/jamaneurol.2020.5157. Epub ahead of print. PMID: 33523098.
• Rehman T, Karp PH, Tan P, Goodell BJ, Pezzulo AA, Thurman AL, Thornell IM, Durfey SL, Duffey ME, Stoltz DA, McKone EF, Singh PK, Welsh MJ. Inflammatory cytokines TNFα and IL-17 enhance the efficacy of cystic fibrosis transmembrane conductance regulator modulators. J Clin Invest. 2021 Jun 24:150398. doi: 10.1172/JCI150398. Epub ahead of print. PMID: 34166230.

Ling Yang, PhD:

• Krongbaramee T, Zhu M, Qian Q, Zhang Z, Eliason S, Shu Y, Qian F, Akkouch A, Su D, Amendt BA, Yang L, Hong L. Plasmid encoding microRNA-200c ameliorates periodontitis and systemic inflammation in obese mice. Mol Ther Nucleic Acids. 2021 Feb 4;23:1204-1216. doi: 10.1016/j.omtn.2021.01.030. PMID: 33664998; PMCID: PMC7899952.
• Qian H, Chao X, Williams J, Fulte S, Li T, Yang L, Ding WX. Autophagy in liver diseases: A review. Mol Aspects Med. 2021 Jun 10:100973. doi: 10.1016/j.mam.2021.100973. Epub ahead of print. PMID: 34120768.
• Chao X, Wang S, Yang L, Ni HM, Ding WX. Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol-impaired TFEB and liver injury in mice. Alcohol Clin Exp Res. 2021 Sep 5. doi: 10.1111/acer.14695. Epub ahead of print. PMID: 34486131.
• Li M, Shao F, Qian Q, Yu W, Zhang Z, Chen B, Su D, Guo Y, Phan AV, Song LS, Stephens SB, Sebag J, Imai Y, Yang L, Cao H. A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells. Mol Ther Nucleic Acids. 2021 Jul 16;26:307-320. doi: 10.1016/j.omtn.2021.06.027. PMID: 34513312; PMCID: PMC8416971.
• Wang S, Chao X, Jiang X, Wang T, Rodriguez Y, Yang L, Pacher P, Ni HM, Ding WX. Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice. Autophagy. 2021 Oct 28:1-11. doi: 10.1080/15548627.2021.1990672. Epub ahead of print. PMID: 34709991.
• Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021 Nov 16;37(7):110003. doi: 10.1016/j.celrep.2021.110003. PMID: 34788615; PMCID: PMC8640996.

Mark Yorek, PhD:

• Coppey L, Obrosov A, Shevalye H, Davidson E, Paradee W, Yorek MA. Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil. J Diabetes Res. 2021 Mar 15;2021:5564477. doi: 10.1155/2021/5564477. PMID: 33816635; PMCID: PMC7987465.
• Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2021 Dec 27:nxab440. doi: 10.1093/jn/nxab440. Epub ahead of print. PMID: 34958390.

Shaoping Zhang, DDS, MS, PhD

• Zhang S, Philips KH, Moss K, Wu D, Adam HS, Selvin E, Demmer RT, Norby FL, Mustapha IZ, Beck JD. Periodontitis and Risk of Diabetes in the Atherosclerosis Risk In Communities (ARIC) Study: A BMI-modified Association. J Clin Endocrinol Metab. 2021 May 13:dgab337. doi: 10.1210/clinem/dgab337. Epub ahead of print. PMID: 33982107.