Featured 2022 Publications of FOEDRC Members


James Ankrum, PhD:

  • Boland L, Bitterlich LM, Hogan AE, Ankrum JA, English K. Translating MSC Therapy in the Age of Obesity. Front Immunol. 2022 Jul 4;13:943333. doi: 10.3389/fimmu.2022.943333. PMID: 35860241; PMCID: PMC9289617.

Wei Bao, PhD:

  • Hart A, Sun Y, Titcomb TJ, Liu B, Smith JK, Correia MLG, Snetselaar LG, Zhu Z, Bao W. Association between preoperative serum albumin levels with risk of death and postoperative complications after bariatric surgery: a retrospective cohort study. Surg Obes Relat Dis. 2022 Jul;18(7):928-934. doi: 10.1016/j.soard.2022.04.006. Epub 2022 Apr 20. PMID: 35660268.
  • Rong S, Li B, Chen L, Sun Y, Du Y, Liu B, Robinson JG, Bao W. Association of Low-Density Lipoprotein Cholesterol Levels with More than 20-Year Risk of Cardiovascular and All-Cause Mortality in the General Population. J Am Heart Assoc. 2022 Aug 2;11(15):e023690. doi: 10.1161/JAHA.121.023690. Epub 2022 Jul 29. PMID: 35904192; PMCID: PMC9375485.
  • Sun Y, Rong S, Liu B, Du Y, Wu Y, Chen L, Xiao Q, Snetselaar L, Wallace R, Bao W. Meal skipping and shorter meal intervals are associated with increased risk of all-cause and cardiovascular disease mortality among U.S. adults. J Acad Nutr Diet. 2022 Aug 11:S2212-2672(22)00874-7. doi: 10.1016/j.jand.2022.08.119. Epub ahead of print. PMID: 35964910.

Christopher Benson, PhD

  • Khataei T, Romig-Martin SA, Harding AMS, Radley JJ, Benson CJ. Comparison of murine behavioural and physiological responses after forced exercise by electrical shock versus manual prodding. Exp Physiol. 2021 Apr;106(4):812-819. doi: 10.1113/EP089117. Epub 2021 Feb 15. PMID: 33527606.
  • Hanson BE, Iwamoto E, Mouser BL, Miller KA, Casey DP. Hypoxia Offsets the Decline in Brachial Artery Flow-mediated Dilation Following Acute Inactivity. Am J Physiol Regul Integr Comp Physiol. 2022 Sep 26. doi: 10.1152/ajpregu.00161.2022. Epub ahead of print. PMID: 36154488.

Sue Bodine, PhD:

  • Baehr LM, Hughes DC, Waddell DS, Bodine SC. SnapShot: Skeletal muscle atrophy. Cell. 2022 Apr 28;185(9):1618-1618.e1. doi: 10.1016/j.cell.2022.03.028. PMID: 35487192.
  • Hughes DC, Baehr LM, Waddell DS, Sharples AP, Bodine SC. Ubiquitin Ligases in Longevity and Aging Skeletal Muscle. Int J Mol Sci. 2022 Jul 9;23(14):7602. doi: 10.3390/ijms23147602. PMID: 35886949; PMCID: PMC9315556.
  • Bodine SC. The role of mTORC1 in the regulation of skeletal muscle mass. Fac Rev. 2022 Nov 11;11:32. doi: 10.12703/r/11-32. PMID: 36532707; PMCID: PMC9720898.

Ryan Boudreau, PhD:

  • Riehle C, Weatherford ET, McCarty NS, Seei A, Jaishy BP, Manivel R, Galuppo P, Allamargot C, Hameed T, Boudreau RL, Bauersachs J, Weiss RM, Abel ED. Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart. Mol Cell Biol. 2022 Sep 20:e0016322. doi: 10.1128/mcb.00163-22. Epub ahead of print. PMID: 36125265.

Lucas Carr, PhD:

  • Oh M, Gabriel KP, Jacobs DR Jr, Bao W, Pierce GL, Carr LJ, Terry JG, Ding J, Carr JJ, Whitaker KM. Cardiorespiratory Fitness in Adults Aged 18 to 34 Years and Long-Term Pericardial Adipose Tissue (from the Coronary Artery Risk Development in Young Adults Study). Am J Cardiol. 2022 Mar 19:S0002-9149(22)00186-2. doi: 10.1016/j.amjcard.2022.02.031. Epub ahead of print. PMID: 35317931
  • Oh M, Jacobs DR Jr, Gabriel KP, Bao W, Pierce GL, Carr LJ, Ding J, Whitaker KM. Cross-Sectional and Longitudinal Associations of Lifestyle Behaviors with Pericardial Adipose Tissue: The MESA Study. Med Sci Sports Exerc. 2022 Jun 1;54(6):984-993. doi: 10.1249/MSS.0000000000002866. Epub 2022 Jan 25. PMID: 35576135; PMCID: PMC9139422.
  • Whitaker KM, Jones MA, Dziewior J, Anderson M, Anderson C, Gibbs BB, Carr LJ. Feasibility, acceptability, and preliminary efficacy of a single-arm, remotely-delivered health coaching intervention to increase physical activity and reduce sedentary behavior during pregnancy. BMC Pregnancy Childbirth. 2022 Oct 2;22(1):740. doi: 10.1186/s12884-022-05073-4. PMID: 36184599; PMCID: PMC9526811.

Darren Casey, PhD:

  • Bock JM, Ueda K, Feider AJ, Hanada S, Casey DP. Combined inorganic nitrate/nitrite supplementation blunts α-mediated vasoconstriction during exercise in patients with type 2 diabetes. Nitric Oxide. 2022 Jan 1;118:17-25. doi: 10.1016/j.niox.2021.10.006. Epub 2021 Oct 27. PMID: 34718145.
  • Bock JM, Hughes WE, Ueda K, Feider AJ, Hanada S, Casey DP. Dietary inorganic nitrate/nitrite supplementation reduces central and peripheral blood pressure in patients with type 2 diabetes mellitus. Am J Hypertens. 2022 May 26:hpac068. doi: 10.1093/ajh/hpac068. Epub ahead of print. PMID: 35639721.
  • Hanson BE, Iwamoto E, Mouser BL, Miller KA, Casey DP. Hypoxia Offsets the Decline in Brachial Artery Flow-mediated Dilation Following Acute Inactivity. Am J Physiol Regul Integr Comp Physiol. 2022 Sep 26. doi: 10.1152/ajpregu.00161.2022. Epub ahead of print. PMID: 36154488.
  • Bock JM, Hanson BE, Miller KA, Seaberg NT, Ueda K, Feider AJ, Hanada S, Lira VA, Casey DP. Eight weeks of inorganic nitrate/nitrite supplementation improves aerobic exercise capacity and the gas exchange threshold in patients with type 2 diabetes. J Appl Physiol (1985). 2022 Dec 1;133(6):1407-1414. doi: 10.1152/japplphysiol.00478.2022. Epub 2022 Nov 3. PMID: 36326473.

Bhagirath Chaurasia, PhD:

  • Jain R, Wade G, Ong I, Chaurasia B, Simcox J. Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles. J Lipid Res. 2022 Mar 14:100197. doi: 10.1016/j.jlr.2022.100197. Epub ahead of print. PMID: 35300982.

Marcelo Correia, MD: 

  • Kamalumpundi V, Shams E, Tucker C, Cheng L, Peterson J, Thangavel S, Ofori O, Correia M. Mechanisms and pharmacotherapy of hypertension associated with type 2 diabetes. Biochem Pharmacol. 2022 Dec;206:115304. doi: 10.1016/j.bcp.2022.115304. Epub 2022 Nov 2. Erratum in: Biochem Pharmacol. 2022 Nov 29;207:115349. PMID: 36341939.

Huxing Cui, PhD: 

  • Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL. Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. Hypertension. 2022 Oct 19. doi: 10.1161/HYPERTENSIONAHA.122.20169. Epub ahead of print. PMID: 36259376.
  • Deng Y, Dickey JE, Saito K, Deng G, Singh U, Jiang J, Toth BA, Zhu Z, Zingman LV, Resch JM, Grobe JL, Cui H. Elucidating the role of Rgs2 expression in the PVN for metabolic homeostasis in mice. Mol Metab. 2022 Oct 25;66:101622. doi: 10.1016/j.molmet.2022.101622. Epub ahead of print. PMID: 36307046; PMCID: PMC9638802.

Joseph Dillon, PhD:

  • Ziogas IA, Dillon JS, Chandrasekharan C, Howe JR. ASO Author Reflections: Surgical Resection Should be Considered in the Multidisciplinary Care of Patients with Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms. Ann Surg Oncol. 2022 Oct 8. doi: 10.1245/s10434-022-12644-4. Epub ahead of print. PMID: 36209329.
  • Ziogas IA, Tasoudis PT, Borbon LC, Sherman SK, Breheny PJ, Chandrasekharan C, Dillon JS, Bellizzi AM, Howe JR. Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms: A Systematic Review and Meta-analysis. Ann Surg Oncol. 2022 Oct 13. doi: 10.1245/s10434-022-12643-5. Epub ahead of print. PMID: 36227392.

Ayotunde Dokun, MD, PhD: 

  • Lamin V, Verry J, Dokun OS, Kronemberger A, Wong T, Lira VA, Dokun AO. microRNA-29a Regulates ADAM12 Through Direct Interaction With ADAM12 mRNA and Modulates Postischemic Perfusion Recovery. J Am Heart Assoc. 2022 Aug 16;11(16):e025727. doi: 10.1161/JAHA.122.025727. Epub 2022 Aug 10. PMID: 35946473.
  • Mani AM, Dhanabalan K, Lamin V, Wong T, Singh MV, Dokun AO. BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease. Int J Mol Sci. 2022 Sep 14;23(18):10715. doi: 10.3390/ijms231810715. PMID: 36142618; PMCID: PMC9502689.

Young-Eun Cho, PhD, RN: 

  • Cho YE, Vorn R, Chimenti M, Crouch K, Shaoshuai C, Narayanaswamy J, Harken A, Schmidt R, Gill J, Lee H. Extracellular vesicle miRNAs in breast milk of obese mothers. Front Nutr. 2022 Oct 12;9:976886. doi: 10.3389/fnut.2022.976886. PMID: 36313069; PMCID: PMC9597365.

Bernd Fritzsch, PhD: 

  • Fritzsch B, Elliott KL, Yamoah EN. Neurosensory development of the four brainstem-projecting sensory systems and their integration in the telencephalon. Front Neural Circuits. 2022 Sep 23;16:913480. doi: 10.3389/fncir.2022.913480. PMID: 36213204; PMCID: PMC9539932.

Lawrence Hunsicker, MD: 

  • Rickels MR, Eggerman TL, Bayman L, Qidwai JC, Alejandro R, Bridges ND, Hering BJ, Markmann JF, Senior PA, Hunsicker LG; Clinical Islet Transplantation Consortium. Long-term Outcomes With Islet-Alone and Islet-After-Kidney Transplantation for Type 1 Diabetes in the Clinical Islet Transplantation Consortium: The CIT-08 Study. Diabetes Care. 2022 Oct 17:dc212688. doi: 10.2337/dc21-2688. Epub ahead of print. PMID: 36250905.

Yumi Imai, MD: 

  • Tong X, Liu S, Stein R, Imai Y. Lipid Droplets' Role in the Regulation of β-Cell Function and β-Cell Demise in Type 2 Diabetes. Endocrinology. 2022 Mar 1;163(3):bqac007. doi: 10.1210/endocr/bqac007. PMID: 35086144; PMCID: PMC8826878.

Randy Kardon, MD, PhD: 

  • Godwin CR, Anders JJ, Cheng L, Elwood BW, Kardon RH, Gramlich OW. Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic Neuritis. Biomolecules. 2022 Oct 7;12(10):1437. doi: 10.3390/biom12101437. PMID: 36291646; PMCID: PMC9599133.

Modar Kassan, PhD:

  • Kassan A, Ait-Aissa K, Kassan M. Gut Microbiota Regulates the Sympathetic Nerve Activity and Peripheral Serotonin Through Hypothalamic MicroRNA-204 in Order to Increase the Browning of White Adipose Tissue in Obesity. Cureus. 2022 Feb 4;14(2):e21913. doi: 10.7759/cureus.21913. PMID: 35155042; PMCID: PMC8820388.

Aloysius Klingelhutz, PhD:

  • Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Joachim-Lehmler H, Ankrum JA, Klingelhutz AJ. Transcriptome sequencing of 3,3',4,4',5-Pentachlorobiphenyl (PCB126)-treated human preadipocytes demonstrates progressive changes in pathways associated with inflammation and diabetes. Toxicol In Vitro. 2022 May 23;83:105396. doi: 10.1016/j.tiv.2022.105396. Epub ahead of print. PMID: 35618242.
  • Gourronc FA, Rebagliati MR, Kramer-Riesberg B, Fleck AM, Patten JJ, Geohegan-Barek K, Messingham KN, Davey RA, Maury W, Klingelhutz AJ. Adipocytes are susceptible to Ebola Virus infection. Virology. 2022 Aug;573:12-22. doi: 10.1016/j.virol.2022.05.007. Epub 2022 May 27. PMID: 35690007; PMCID: PMC9413353.
  • Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Lehmler HJ, Ankrum JA, Klingelhutz AJ. Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3',4,4',5-Pentachlorobiphenyl (PCB126). Data Brief. 2022 Sep 1;45:108571. doi: 10.1016/j.dib.2022.108571. PMID: 36131953; PMCID: PMC9483567.

Helena Laroche, MD: 

  • Laroche HH, Park-Mroch J, O'Shea A, Rice S, Cintron Y, Engebretsen B. Resource mobilization combined with motivational interviewing to promote healthy behaviors and healthy weight in low-income families: An intervention feasibility study. SAGE Open Med. 2022 Jun 11;10:20503121221102706. doi: 10.1177/20503121221102706. PMID: 35707344; PMCID: PMC9189556.

Vitor Lira, PhD:

  • Senna GW, Dantas EHM, Scudese E, Brandão PP, Lira VA, Baffi M, Ribeiro LCP, Simão R, Thomas E, Bianco A. Higher Muscle Damage Triggered by Shorter Inter-Set Rest Periods in Volume-Equated Resistance Exercise. Front Physiol. 2022 Feb 28;13:827847. doi: 10.3389/fphys.2022.827847. PMID: 35295573; PMCID: PMC8920480.
  • Turner KD, Kronemberger A, Bae D, Bock JM, Hughes WE, Ueda K, Feider AJ, Hanada S, de Sousa LGO, Harris MP, Anderson EJ, Bodine SC, Zimmerman MB, Casey DP, Lira VA. Effects of Combined Inorganic Nitrate and Nitrite Supplementation on Cardiorespiratory Fitness and Skeletal Muscle Oxidative Capacity in Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients. 2022 Oct 25;14(21):4479. doi: 10.3390/nu14214479. PMID: 36364742; PMCID: PMC9654804.

Ashutosh Mangalam, PhD:

  • Marietta E, Horwath I, Meyer S, Khaleghi-Rostamkolaei S, Norman E, Luckey D, Balakrishnan B, Mangalam A, Choung RS, Taneja V, Murray JA. Administration of Human Derived Upper gut Commensal Prevotella histicola delays the onset of type 1 diabetes in NOD mice. BMC Microbiol. 2022 Jan 4;22(1):8. doi: 10.1186/s12866-021-02406-9. PMID: 34983374; PMCID: PMC8729070.
  • Shahi SK, Ghimire S, Lehman P, Mangalam AK. Obesity induced gut dysbiosis contributes to disease severity in an animal model of multiple sclerosis. Front Immunol. 2022 Sep 9;13:966417. doi: 10.3389/fimmu.2022.966417. PMID: 36164343; PMCID: PMC9509138.
  • Shrode RL, Cady N, Jensen SN, Borcherding N, Mangalam AK. Isoflavone consumption reduces inflammation through modulation of phenylalanine and lipid metabolism. Metabolomics. 2022 Oct 26;18(11):84. doi: 10.1007/s11306-022-01944-1. PMID: 36289122.

Mohamad Mokadem, MD: 

  • Herz H, Song Y, Ye Y, Tian L, Linden B, Abu El Haija M, Chu Y, Grobe JL, Lengeling RW, Mokadem M. NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion. Nutrients. 2021 Dec 28;14(1):120. doi: 10.3390/nu14010120. PMID: 35010994; PMCID: PMC8746549.
  • Xi J, Ye Y, Mokadem M, Yuan J, Kawai M. The effect of gender and obesity in modulating cross-bridge function in cardiac muscle fibers. J Muscle Res Cell Motil. 2022 Aug 22. doi: 10.1007/s10974-022-09627-z. Epub ahead of print. PMID: 35994221.

Andrew Norris, MD, PhD: 

  • Gunasekar SK, Xie L, Kumar A, Hong J, Chheda PR, Kang C, Kern DM, My-Ta C, Maurer J, Heebink J, Gerber EE, Grzesik WJ, Elliot-Hudson M, Zhang Y, Key P, Kulkarni CA, Beals JW, Smith GI, Samuel I, Smith JK, Nau P, Imai Y, Sheldon RD, Taylor EB, Lerner DJ, Norris AW, Klein S, Brohawn SG, Kerns R, Sah R. Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. Nat Commun. 2022 Feb 10;13(1):784. doi: 10.1038/s41467-022-28435-0. PMID: 35145074; PMCID: PMC8831520.
  • Uc A, Strandvik B, Yao J, Liu X, Yi Y, Sun X, Welti R, Engelhardt JF, Norris AW. The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models. Clin Sci (Lond). 2022 Dec 22;136(24):1773-1791. doi: 10.1042/CS20220450. PMID: 36416119.

Brian O'Neill, MD, PhD:

  • Bhardwaj G, Penniman CM, Klaus K, Weatherford ET, Pan H, Dreyfuss JM, Nair KS, Kahn CR, O'Neill BT. Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors. Front Physiol. 2022 Feb 4;12:779121. doi: 10.3389/fphys.2021.779121. PMID: 35185597; PMCID: PMC8855073.
  • Penniman CM, Bhardwaj G, Nowers CJ, Brown CU, Junck TL, Boyer CK, Jena J, Fuqua JD, Lira VA, O'Neill BT. Loss of FoxOs in muscle increases strength and mitochondrial function during aging. J Cachexia Sarcopenia Muscle. 2022 Nov 28. doi: 10.1002/jcsm.13124. Epub ahead of print. PMID: 36442857.

Gary Pierce, PhD: 

  • DuBose LE, Weng TB, Pierce GL, Wharff C, Reist L, Hamilton C, O'Deen A, Dubishar KM, Lane-Cordova AD, Voss MW. Association Between Cardiorespiratory Fitness and Cerebrovascular Reactivity to a Breath Hold Stimulus in Older Adults: Influence of Aerobic Exercise Training. J Appl Physiol (1985). 2022 Apr 28. doi: 10.1152/japplphysiol.00599.2021. Epub ahead of print. PMID: 35482329.
  • Dziewior J, Carr LJ, Pierce GL, Whitaker K. College students report less physical activity and more sedentary behavior during the COVID-19 pandemic. J Am Coll Health. 2022 Jul 26:1-9. doi: 10.1080/07448481.2022.2100708. Epub ahead of print. PMID: 35881778.
  • Nuckols VR, Stroud AK, Armstrong MK, Brandt DS, Santillan MK, Santillan DA, Pierce GL. Postpartum ambulatory and home blood pressure monitoring in women with history of preeclampsia: Diagnostic agreement and detection of masked hypertension. Pregnancy Hypertens. 2022 Aug;29:23-29. doi: 10.1016/j.preghy.2022.05.003. Epub 2022 May 10. PMID: 35671544.

Matthew Potthoff, PhD:

  • Claflin KE, Sullivan AI, Naber MC, Flippo KH, Morgan DA, Neff TJ, Jensen-Cody SO, Zhu Z, Zingman LV, Rahmouni K, Potthoff MJ. Pharmacological FGF21 signals to glutamatergic neurons to enhance leptin action and lower body weight during obesity. Mol Metab. 2022 Aug 6;64:101564. doi: 10.1016/j.molmet.2022.101564. Epub ahead of print. PMID: 35944896; PMCID: PMC9403559.
  • Zhou B, Claflin KE, Flippo KH, Sullivan AI, Asghari A, Tadinada SM, Jensen-Cody SO, Abel T, Potthoff MJ. Central FGF21 production regulates memory but not peripheral metabolism. Cell Rep. 2022 Aug 23;40(8):111239. doi: 10.1016/j.celrep.2022.111239. PMID: 36001982.
  • Pereira RO, Olvera AC, Marti A, Fang S, White JR, Westphal M, Hewezi R, AshShareef ST, Pena LMG, Koneru J, Potthoff MJ, Abel ED. OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice. Diabetes. 2022 Sep 28:db220450. doi: 10.2337/db22-0450. Epub ahead of print. PMID: 36170659.

Kamal Rahmouni, PhD:

  • Rouabhi M, Guo DF, Morgan DA, Zhu Z, López M, Zingman L, Grobe JL, Rahmouni K. BBSome ablation in SF1 neurons causes obesity without comorbidities. Mol Metab. 2021 Jun;48:101211. doi: 10.1016/j.molmet.2021.101211. Epub 2021 Mar 13. PMID: 33722691; PMCID: PMC8065214.
  • Rial-Pensado E, Freire-Agulleiro O, Ríos M, Guo DF, Contreras C, Seoane-Collazo P, Tovar S, Nogueiras R, Diéguez C, Rahmouni K, López M. Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome. Mol Metab. 2022 Feb 23;59:101465. doi: 10.1016/j.molmet.2022.101465. Epub ahead of print. PMID: 35218946; PMCID: PMC8933534.
  • Oliveira V, Riedl RA, Claflin KE, Marin Mathieu N, Ritter ML, Balapattabi K, Wackman KK, Reho JJ, Brozoski DT, Morgan DA, Cui H, Rahmouni K, Burnett CML, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL. Melanocortin MC4R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain. Physiol Genomics. 2022 Apr 27. doi: 10.1152/physiolgenomics.00015.2022. Epub ahead of print. PMID: 35476598.
  • Rahmouni K. Energy metabolism and syncope. Clin Auton Res. 2022 Dec;32(6):391-393. doi: 10.1007/s10286-022-00906-w. Epub 2022 Nov 3. PMID: 36326945.

Robet Roghair, PhD:

  • Chatmethakul T, Schmelzel ML, Johnson KJ, Walker JR, Santillan DA, Colaizy TT, Roghair RD. Postnatal Leptin Levels Correlate with Breast Milk Leptin Content in Infants Born before 32 Weeks Gestation. Nutrients. 2022 Dec 8;14(24):5224. doi: 10.3390/nu14245224. PMID: 36558383; PMCID: PMC9782260.

Jennifer Robinson, PhD:

  • Lai HTM, Imamura F, Korat AVA, Murphy RA, Tintle N, Bassett JK, Chen J, Kröger J, Chien KL, Senn M, Wood AC, Forouhi NG, Schulze MB, Harris WS, Vasan RS, Hu F, Giles GG, Hodge A, Djousse L, Brouwer IA, Qian F, Sun Q, Wu JHY, Marklund M, Lemaitre RN, Siscovick DS, Fretts AM, Shadyab AH, Manson JE, Howard BV, Robinson JG, Wallace RB, Wareham NJ, Chen YI, Rotter JI, Tsai MY, Micha R, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE). Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis of 12 Prospective Cohort Studies in the Fatty Acids and Outcomes Research Consortium (FORCE). Diabetes Care. 2022 Feb 10:dc211756. doi: 10.2337/dc21-1756. Epub ahead of print. PMID: 35142845.
  • Chi CL, Wang J, Ying Yew P, Lenskaia T, Loth M, Mani Pradhan P, Liang Y, Kurella P, Mehta R, Robinson JG, Tonellato PJ, Adam TJ. Producing personalized statin treatment plans to optimize clinical outcomes using big data and machine learning. J Biomed Inform. 2022 Apr;128:104029. doi: 10.1016/j.jbi.2022.104029. Epub 2022 Feb 16. PMID: 35182785.

Julien Sebag, PhD:

  • Rouault AAJ, Buscaglia P, Sebag JA. MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation. J Biol Chem. 2022 May 20:102057. doi: 10.1016/j.jbc.2022.102057. Epub ahead of print. PMID: 35605660.

William Sivitz, MD:

  • Braffett BH, Bebu I, El Ghormli L, Cowie CC, Sivitz WI, Pop-Busui R, Larkin ME, Gubitosi-Klug RA, Nathan DM, Lachin JM, Dagogo-Jack S; DCCT/EDIC Research Group. Cardiometabolic Risk Factors and Incident Cardiovascular Disease Events in Women vs Men With Type 1 Diabetes. JAMA Netw Open. 2022 Sep 1;5(9):e2230710. doi: 10.1001/jamanetworkopen.2022.30710. PMID: 36074461.
  • Yu L, Fink BD, Som R, Rauckhorst AJ, Taylor EB, Sivitz WI. Metabolic clearance of oxaloacetate and mitochondrial complex II respiration: Divergent control in skeletal muscle and brown adipose tissue. Biochim Biophys Acta Bioenerg. 2023 Jan 1;1864(1):148930. doi: 10.1016/j.bbabio.2022.148930. Epub 2022 Oct 19. PMID: 36272463.

Linda Snetselaar, PhD:

  • Prentice RL, Pettinger M, Zheng C, Neuhouser ML, Raftery D, Gowda GAN, Huang Y, Tinker LF, Howard BV, Manson JE, Van Horn L, Wallace R, Mossavar-Rahmani Y, Johnson KC, Snetselaar L, Lampe JW. Biomarkers for Components of Dietary Protein and Carbohydrate with Application to Chronic Disease Risk Among Postmenopausal Women. J Nutr. 2022 Jan 7:nxac004. doi: 10.1093/jn/nxac004. Epub ahead of print. PMID: 35015878.
  • Schwalb ME, Smith-Warner SA, Hou J, Rohan TE, Snetselaar L, Luo J, Genkinger JM. Sustained weight loss, weight cycling, and weight gain during adulthood and pancreatic cancer incidence in the Women's Health Initiative (US). Am J Epidemiol. 2022 Feb 1:kwac016. doi: 10.1093/aje/kwac016. Epub ahead of print. PMID: 35102370.
  • Zheng C, Pettinger M, Gowda GAN, Lampe JW, Raftery D, Tinker LF, Huang Y, Navarro SL, O'Brien DM, Snetselaar L, Liu S, Wallace RB, Neuhouser ML, Prentice RL. Biomarker-Calibrated Red and Combined Red and Processed Meat Intakes with Chronic Disease Risk in a Cohort of Postmenopausal Women. J Nutr. 2022 Jul 6;152(7):1711-1720. doi: 10.1093/jn/nxac067. PMID: 35289908; PMCID: PMC9258528.
  • Xu G, Snetselaar LG, Strathearn L, Ryckman K, Nothwehr F, Torner J. Association between history of attention-deficit/hyperactivity disorder diagnosis and cardiovascular disease in U.S. adults. Health Psychol. 2022 Jul 18. doi: 10.1037/hea0001193. Epub ahead of print. PMID: 35849359.
  • Pan K, Aragaki AK, Michael Y, Thomson CA, Snetselaar LG, Wactawski-Wende J, Garcia DO, Dieli-Conwright CM, Shadyab AH, Saquib N, Chlebowski RT. Long-term dietary intervention influence on physical activity in the Women's Health Initiative Dietary Modification randomized trial. Breast Cancer Res Treat. 2022 Aug;195(1):43-54. doi: 10.1007/s10549-022-06655-8. Epub 2022 Jul 12. PMID: 35821536.
  • Pichardo MS, Esserman D, Ferrucci LM, Molina Y, Chlebowski RT, Pan K, Garcia DO, Lane DS, Shadyab AH, Lopez-Pentecost M, Luo J, Kato I, Springfield S, Rosal MC, Bea JW, Cespedes Feliciano EM, Qi L, Nassir R, Snetselaar L, Manson J, Bird C, Irwin ML. Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity-related cancer risk and mortality in Black and Latina Women's Health Initiative participants. Cancer. 2022 Oct;128(20):3630-3640. doi: 10.1002/cncr.34428. Epub 2022 Aug 23. PMID: 35996861.
  • Snetselaar L, Cheek JJ, Fox SS, Healy HS, Schweizer ML, Bao W, Kamholz J, Titcomb TJ. Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: A Systematic Review and Network Meta-analysis of Randomized Trials. Neurology. 2022 Oct 18:10.1212/WNL.0000000000201371. doi: 10.1212/WNL.0000000000201371. Epub ahead of print. PMID: 36257717.
  • Bailey RL, Stang JS, Davis TA, Naimi TS, Schneeman BO, Dewey KG, Donovan SM, Novotny R, Kleinman RE, Taveras EM, Bazzano L, Snetselaar LG, de Jesus J, Casavale KO, Stoody EE, Goldman JD, Moshfegh AJ, Rhodes DG, Herrick KA, Koegel K, Perrine CG, Pannucci T. Dietary and Complementary Feeding Practices of US Infants, 6 to 12 Months: A Narrative Review of the Federal Nutrition Monitoring Data. J Acad Nutr Diet. 2022 Dec;122(12):2337-2345.e1. doi: 10.1016/j.jand.2021.10.017. Epub 2021 Oct 21. PMID: 34688966.
  • Ringel NE, Hovey KM, Andrews CA, Mossavar-Rahmani Y, Shadyab AH, Snetselaar LG, Howard BV, Iglesia CB. Artificially sweetened beverages and urinary incontinence-a secondary analysis of the Women's Health Initiative Observational Study. Menopause. 2022 Dec 13. doi: 10.1097/GME.0000000000002129. Epub ahead of print. PMID: 36515559.
  • Sun Y, Liu B, Snetselaar LG, Wallace RB, Shadyab AH, Chen GC, Shikany JM, Manson JE, Bao W. Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative. J Acad Nutr Diet. 2022 Dec 19:S2212-2672(22)01256-4. doi: 10.1016/j.jand.2022.12.007. Epub ahead of print. PMID: 36549566.
  • Titcomb TJ, Liu B, Wahls TL, Snetselaar LG, Shadyab AH, Tabung FK, Saquib N, Arcan C, Tinker LF, Wallace RB, Bao W. Comparison of the Ketogenic Ratio of Macronutrients with the Low-Carbohydrate Diet Score and their Association with Risk of Type 2 Diabetes in Postmenopausal Women: A Secondary Analysis of the Women's Health Initiative. J Acad Nutr Diet. 2022 Dec 20:S2212-2672(22)01253-9. doi: 10.1016/j.jand.2022.12.004. Epub ahead of print. PMID: 36549565.

Long-Sheng Song, PhD:

  • Yoon JY, Daneshgar N, Chu Y, Chen B, Hefti M, Vikram A, Irani K, Song LS, Brenner C, Abel ED, London B, Dai DF. Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome. Clin Transl Med. 2022 Jul;12(7):e954. doi: 10.1002/ctm2.954. PMID: 35872650; PMCID: PMC9309541.
  • Ji XY, Zheng D, Ni R, Wang JX, Shao JQ, Vue Z, Hinton A Jr, Song LS, Fan GC, Chakrabarti S, Su ZL, Peng TQ. Sustained over-expression of calpain-2 induces age-dependent dilated cardiomyopathy in mice through aberrant autophagy. Acta Pharmacol Sin. 2022 Nov;43(11):2873-2884. doi: 10.1038/s41401-022-00965-9. Epub 2022 Aug 19. PMID: 35986214; PMCID: PMC9622835.
  • Hall DD, Shi Q, Song LS. Prohibiting MG53 Phosphorylation Optimizes its Therapeutic Potential in Diabetes. Circ Res. 2022 Dec 2;131(12):977-979. doi: 10.1161/CIRCRESAHA.122.322132. Epub 2022 Dec 1. PMID: 36454851; PMCID: PMC9718506.

Milan Sonka, PhD: 

  • Chang J, Liu Y, Saey SA, Chang KC, Shrader HR, Steckly KL, Rajput M, Sonka M, Chan CHF. Machine-learning based investigation of prognostic indicators for oncological outcome of pancreatic ductal adenocarcinoma. Front Oncol. 2022 Dec 8;12:895515. doi: 10.3389/fonc.2022.895515. PMID: 36568148; PMCID: PMC9773248.

Anna Stanhewicz, PhD: 

  • Stanhewicz AE, Schlarmann RL, Brustkern KM, Jalal D. Oxidative stress contributes to reductions in microvascular endothelial- and nitric oxide-dependent dilation in women with a history of gestational diabetes. J Appl Physiol (1985). 2022 Jul 7. doi: 10.1152/japplphysiol.00189.2022. Epub ahead of print. PMID: 35796611.
  • Dillon GA, Stanhewicz AE, Serviente C, Flores VA, Stachenfeld N, Alexander LM. Seven days of statin treatment improves nitric-oxide mediated endothelial-dependent cutaneous microvascular function in women with endometriosis. Microvasc Res. 2022 Aug 12;144:104421. doi: 10.1016/j.mvr.2022.104421. Epub ahead of print. PMID: 35970408.

Samuel Stephens, PhD:

  • Rohli KE, Boyer CK, Blom SE, Stephens SB. Nutrient Regulation of Pancreatic Islet β-Cell Secretory Capacity and Insulin Production. Biomolecules. 2022 Feb 20;12(2):335. doi: 10.3390/biom12020335. PMID: 35204835; PMCID: PMC8869698.
  • Parchure A, Tian M, Stalder D, Boyer CK, Bearrows SC, Rohli KE, Zhang J, Rivera-Molina F, Ramazanov BR, Mahata SK, Wang Y, Stephens SB, Gershlick DC, von Blume J. Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules. J Cell Biol. 2022 Dec 5;221(12):e202206132. doi: 10.1083/jcb.202206132. Epub 2022 Sep 29. PMID: 36173346; PMCID: PMC9526250.
  • Rohli KE, Boyer CK, Bearrows SC, Moyer MR, Elison WS, Bauchle CJ, Blom SE, Zhang J, Wang Y, Stephens SB. ER Redox Homeostasis Regulates Proinsulin Trafficking and Insulin Granule Formation in the Pancreatic Islet β-Cell. Function (Oxf). 2022 Sep 28;3(6):zqac051. doi: 10.1093/function/zqac051. PMID: 36325514; PMCID: PMC9614934.

Eric Taylor, PhD: 

  • Rauckhorst AJ, Borcherding N, Pape DJ, Kraus AS, Scerbo DA, Taylor EB. Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments. Mol Metab. 2022 Sep 10:101596. doi: 10.1016/j.molmet.2022.101596. Epub ahead of print. PMID: 36100179.
  • Buchanan JL, Tormes Vaquerano J, Taylor EB. Isolated Effects of Plasma Freezing versus Thawing on Metabolite Stability. Metabolites. 2022 Nov 11;12(11):1098. doi: 10.3390/metabo12111098. PMID: 36422241; PMCID: PMC9693613.

Michael Tansey, MD:

  • Reiss AL, Jo B, Arbelaez AM, Tsalikian E, Buckingham B, Weinzimer SA, Fox LA, Cato A, White NH, Tansey M, Aye T, Tamborlane W, Englert K, Lum J, Mazaika P, Foland-Ross L, Marzelli M, Mauras N; Diabetes Research in Children Network (DirecNet) Consortium. A Pilot randomized trial to examine effects of a hybrid closed-loop insulin delivery system on neurodevelopmental and cognitive outcomes in adolescents with type 1 diabetes. Nat Commun. 2022 Aug 30;13(1):4940. doi: 10.1038/s41467-022-32289-x. PMID: 36042217.
  • Parra Villasmil MG, Patel S, Tansey M, Badheka A, Chegondi M. A Rare Presentation of New-Onset Type 1 Diabetes Mellitus in a Developmentally Delayed Child With an Overlap of Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State. Cureus. 2022 Sep 9;14(9):e28983. doi: 10.7759/cureus.28983. PMID: 36237743; PMCID: PMC9548379.

Aliye Uc, PhD:

  • Trout AT, Abu-El-Haija M, Anupindi SA, Marine MB, Murati M, Phelps AS, Rees MA, Squires JH, Ellery KM, Gariepy CE, Maqbool A, McFerron BA, Perito ER, Schwarzenberg SJ, Zhang B, Andersen DK, Lowe ME, Uc A; Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC). Interobserver Agreement for CT and MRI Findings of Chronic Pancreatitis in Children: A Multicenter Ancillary Study Under the INSPPIRE Consortium. AJR Am J Roentgenol. 2022 Feb 23. doi: 10.2214/AJR.21.27234. Epub ahead of print. PMID: 35195432.
  • Gariepy CE, Lara LF, Easler JJ, Shaikhkhalil A, Uc A. Pediatric to adult transfer of care in patients with pancreas disease: Recommendations for care and research opportunities. Am J Gastroenterol. 2022 Jul 21. doi: 10.14309/ajg.0000000000001910. Epub ahead of print. PMID: 35862827.
  • O'Malley Y, Coleman MC, Sun X, Lei J, Yao J, Pulliam CF, Kluz P, McCormick ML, Yi Y, Imai Y, Engelhardt JF, Norris AW, Spitz DR, Uc A. Oxidative stress and impaired insulin secretion in cystic fibrosis pig pancreas. Adv Redox Res. 2022 Jul;5:100040. doi: 10.1016/j.arres.2022.100040. Epub 2022 Jun 9. PMID: 35903252; PMCID: PMC9328447.
  • Uc A, Cress GA, Wang F, Abu-El-Haija M, Ellery KM, Fishman DS, Gariepy CE, Gonska T, Lin TK, Liu QY, Mehta M, Maqbool A, McFerron BA, Morinville VD, Ooi CY, Perito ER, Schwarzenberg SJ, Sellers ZM, Serrano J, Shah U, Troendle DM, Wilschanski M, Zheng Y, Yuan Y, Lowe ME; Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer. Analysis of INSPPIRE-2 Cohort: Risk Factors and Disease Burden in Children With Acute Recurrent or Chronic Pancreatitis. J Pediatr Gastroenterol Nutr. 2022 Nov 1;75(5):643-649. doi: 10.1097/MPG.0000000000003590. Epub 2022 Aug 17. PMID: 35976273; PMCID: PMC9617760.
  • Uc A, Strandvik B, Yao J, Liu X, Yi Y, Sun X, Welti R, Engelhardt JF, Norris AW. The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models. Clin Sci (Lond). 2022 Dec 22;136(24):1773-1791. doi: 10.1042/CS20220450. PMID: 36416119; PMCID: PMC9747517.

Yuriy Usachev, PhD

  • Klomp A, Omichi R, Iwasa Y, Smith RJ, Usachev YM, Russo AF, Narayanan NS, Lee A. The voltage-gated Ca2+ channel subunit α2δ-4 regulates locomotor behavior and sensorimotor gating in mice. PLoS One. 2022 Mar 30;17(3):e0263197. doi: 10.1371/journal.pone.0263197. PMID: 35353835; PMCID: PMC8967030.

Ajit Vikram, PhD: 

  • Gaddam RR, Dhuri K, Kim YR, Jacobs JS, Kumar V, Li Q, Irani K, Bahal R, Vikram A. γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet. J Med Chem. 2022 Feb 24;65(4):3332-3342. doi: 10.1021/acs.jmedchem.1c01831. Epub 2022 Feb 8. PMID: 35133835; PMCID: PMC8883473.

Michael Welsh, MD:

  • Simmering JE, Welsh MJ, Schultz J, Narayanan NS. Use of Glycolysis-Enhancing Drugs and Risk of Parkinson's Disease. Mov Disord. 2022 Aug 22. doi: 10.1002/mds.29184. Epub ahead of print. PMID: 36054705.

Ling Yang, PhD:

  • Wang S, Chao X, Jiang X, Wang T, Rodriguez Y, Yang L, Pacher P, Ni HM, Ding WX. Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice. Autophagy. 2022 Jul;18(7):1572-1582. doi: 10.1080/15548627.2021.1990672. Epub 2021 Oct 28. PMID: 34709991; PMCID: PMC9298442.
  • Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021 Nov 16;37(7):110003. doi: 10.1016/j.celrep.2021.110003. PMID: 34788615; PMCID: PMC8640996.

Mark Yorek, PhD

  • Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr 1;152(4):926-938. doi: 10.1093/jn/nxab440. PMID: 34958390; PMCID: PMC8970988.
  • Yorek MA. Diabetic Neuropathy: In Search of a Treatment. Curr Diabetes Rev. 2022;18(5):1-2. doi: 10.2174/157339981805220407104606. PMID: 35545970.

Leonid Zingman, PhD: 

  • Zhu Z, Gao Z, Chen B, Hall DD, Minerath R, Koval O, Sierra A, Subbotina E, Zhu X, Kim YR, Yang J, Grumbach I, Irani K, Grueter C, Song LS, Hodgson-Zingman DM, Zingman LV. Atrial-paced, exercise-similar heart rate envelope induces myocardial protection from ischaemic injury. Europace. 2022 Jul 15;24(6):1025-1035. doi: 10.1093/europace/euab273. PMID: 34792112; PMCID: PMC9282913.