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Katie Larson Ode, MD, MS

Contact Information

Office: BT-2022
Phone: 319-356-7251
Faculty Profile


Brief description of current research:

Dr. Larson Ode’s research is focused on the pathophysiology of cystic fibrosis related diabetes mellitus, specifically the onset of glycemic abnormalities in very young children with Cystic Fibrosis. CFRD is very common in patients with cystic fibrosis and increases morbidity and mortality. Her studies have shown that glycemic abnormalities begin much earlier in cystic fibrosis than previously understood. This has direct implications for the understanding of the pathophysiology of CFRD and timing of screening for, and potentially treatment of, glycemic abnormalities in children with Cystic Fibrosis. Recent studies have focused on glycemic abnormalities in extremely young children and animals with cystic fibrosis and the relationship to other indicators of pancreatic endocrine and exocrine function.

3 most influential diabetes/obesity/metabolism publications:

  • Ode KL, Frohnert B, Laguna T, Phillips J, Holme B, Regelmann W, Thomas W, Moran A. Oral glucose tolerance testing in children with cystic fibrosis. Pediatr Diabetes. 2010 Nov;11(7):487-92.
  • Ode KL, Moran A. New insights into cystic fibrosis related diabetes in children. The Lancet Diabetes Endocrinol. 2013 Sep;1(1):52-8. doi: 10.1016/S2213-8587(13) 70015-9. Epub 2013 May 23 (invited review)
  • Su H, Yi Y, Yao J, Sun X, Hu S, Uc A, Nelson DJ, Ode KL, Philipson LH, Engelhardt JF, Norris AW. Quantifying insulin sensitivity and entero-insular responsiveness to hyper and hypoglycemia in Ferrets. PLoS ONE 2014 Mar; 9(3): e90519. doi:10.1371/journal.pone.0090519

 

Quote:

 I love the University of Iowa because of our wonderful CFRD research team, and the honor and privilege of caring for the children of Iowa.