William Sivitz, MD

Contact Information

Office: E422 GH 
Phone: 319-353-7812 
Faculty Profile


Brief description of current research:

My research interests include the control of cellular energy utilization with emphasis on mitochondrial function as affected by diabetes and obesity. I am also investigating the mechanisms by which mitochondria regulate reactive oxygen production and the relationship of oxygen radicals to the pathophysiology of diabetes and obesity. My laboratory has extensive experience and has generated several publications regarding mitochondrial function in both the isolated organelles and intact cells. I have also carried out investigator initiated clinical research in obesity and diabetes and participate in multi-centered clinical trials as Iowa site PI.

3 most influential diabetes/obesity/metabolism publications:

  • Yu L, Fink BD, Herlein JA, Sivitz WI: Mitochondrial function in diabetes: Novel methodology and new insight. Diabetes, Jun;62(6):1833-42, 2013
  • Fink BD, Herlein JA, Yorek MA, Fenner AM, Kerns RJ and Sivitz WI: Bioenergetic Effects of Mitochondrial Targeted Coenzyme Q Analogs in Endothelial Cells. J Pharmacol Exp Ther. 342:709-19, 2012.
  • Mehra R, Tsalikian E, and Sivitz WI: Feeding Frequency and Appetite in Lean and Obese Pre-pubertal Children, Obesity. 19:560-7, 2011

Quote:

“Research will make a difference; we need to keep at it.”