David Stoltz, MD, PhD

Contact Information

Office: 6322 PBDB
Phone: 319-335-9233
Faculty Profile


Brief description of current research:

Dr. Stoltz's clinical interests include general pulmonary diseases and lung infections. His research focuses on the pathogenesis of cystic fibrosis related airway disease with a particular emphasis on studying airway epithelial and smooth muscle cells, the role of paraoxonases (PONs) on Pseudomonas aeruginosa quorum-sensing regulation, mucociliary clearance, and advanced airway imaging modalities and analysis.

 

3 most influential diabetes/obesity/metabolism publications:

  • Stoltz DA, Meyerholz DK, Welsh MJ. Origins of cystic fibrosis lung disease. N Engl J Med. 2015 Jan 22;372(4):351-62. doi: 10.1056/NEJMra1300109. Review. No abstract available.
  • Hoegger MJ, Fischer AJ, McMenimen JD, Ostedgaard LS, Tucker AJ, Awadalla MA, Moninger TO, Michalski AS, Hoffman EA, Zabner J, Stoltz DA, Welsh MJ. Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis. Science. 2014 Aug 15;345(6198):818-22. doi: 10.1126/science.1255825.
  • Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, Wallen TJ, Wohlford-Lenane C, McMenimen JD, Chen JH, Bogan KL, Adam RJ, Hornick EE, Nelson GA 4th, Hoffman EA, Chang EH, Zabner J, McCray PB Jr, Prather RS, Meyerholz DK, Welsh MJ. Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. J Clin Invest. 2013 Jun;123(6):2685-93. doi: 10.1172/JCI68867. Epub 2013 May 8.