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Facility Information

Human postmortem brain
FFPE blocks
Viewing cultures on screen
Tissue culture
Donor fibroblasts
Facility microscope
Researcher in lab using microscope

As the leading global cause of disability, human brain disorders are a complex and multi-dimensional burden across generations. There is a critical gap for effective translation between discovery and therapeutics for human brain disorders due to the limited access to human brain specimens.

Made possible through a generous gift by the Roy J. Carver Charitable Trust and donor families, Iowa NeuroBank Core supports the operation and activities of the shared research resources in human brain research, as a collaborative effort in the Iowa Neuroscience Institute and Departments of Pathology, Neurology, Psychiatry, Neuroscience, and Pharmacology at the University of Iowa to facilitate human brain research. 

Iowa NeuroBank Core was established in 2020 to offer dual services of neurobanking and neurotechnology. We charge for services that directly support the research or academic mission and recover costs through charges to internal or external users. 

In order to ensure that researchers have the most accurate information, the NeuroBank Core will provide the researcher with the most current information when you submit the request forms. Our team is looking forward to partnering with researchers, core facilities, industry, and donors through all the stages of research development.

Capturing a spectrum of neuropathology in the human brain to help researchers advance human brain research and personalized medicine:

  1. "Neurotypical" (healthy controls): from fetus to adults over 98 years old

  2. Alzheimer's disease (AD)

  3. Frontotemporal dementia (FTD): Frontotemporal lobar degeneration (FTLD) families, including FTLD-tau, FTLD-TDP43, FTLD-UPS, FTLD-C9orf72, progressive supranuclear palsy (PSP)

  4. Primary age-related tauopathy (PART) 

  5. Amyotrophic lateral sclerosis (ALS)

  6. Huntington's disease (HD): juvenile-onset HD (JOHD), adult-onset Huntington's Disease (AOHD)

  7. Multiple sclerosis (MS)

  8. Multiple system atrophy (MSA)

  9. Lewy body disease (LBD)

  10. Parkinson's disease (PD)

  11. Alcohol use disorder: alcoholism, alcohol dependence, alcohol dependence, alcoholism, alcohol addiction

  12. SARS-CoV-2 (COVID-19)

  13. Schizophrenia

  14. Epilepsy

  15. Essential Tremor

  16. Sudden Unexpected Death in Epilepsy (SUDEP) 

  17. 1p36 deletion syndrome

  18. Trisomy 21

  19. Snyder-Robinson Syndrome

  20. COL4A1 mutation

  21. Hypoxic-ischemic injury

  22. Diabetes: diabetes mellitus, type 1 (DM, type 1), diabetes mellitus type 2 (DM, type 2), steroid-induced diabetes, gestational diabetes mellitus (GDM)

  23. Obesity

Specimen collection options:

  1. Brain tissues
  2. Meninges
  3. Choroid plexus
  4. Blood
  5. Fibroblasts