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Facility Information

Human postmortem brain
FFPE blocks
Viewing cultures on screen
Tissue culture
Donor fibroblasts
Facility microscope
Researcher in lab using microscope

Capturing a Spectrum of Neuropathology in the Human Brains

  1. "Neurotypical" (healthy controls): from fetus to adults over 98 years old

  2. Alzheimer's disease (AD)

  3. Frontotemporal dementia (FTD): Frontotemporal lobar degeneration (FTLD) families, including FTLD-tau, FTLD-TDP43, FTLD-UPS, FTLD-C9orf72, progressive supranuclear palsy (PSP)

  4. Primary age-related tauopathy (PART) 

  5. Amyotrophic lateral sclerosis (ALS)

  6. Huntington's disease (HD): juvenile-onset HD (JOHD), adult-onset Huntington's Disease (AOHD)

  7. Multiple sclerosis (MS)

  8. Lewy body disease (LBD)

  9. Parkinson's disease (PD)

  10. Alcohol use disorder: alcoholism, alcohol dependence, alcohol dependence, alcoholism, alcohol addiction

  11. SARS-CoV-2 (COVID-19)

  12. Schizophrenia

  13. Epilepsy

  14. Essential Tremor

  15. Sudden Unexpected Death in Epilepsy (SUDEP) 

  16. 1p36 deletion syndrome

  17. Trisomy 21

  18. Snyder-Robinson Syndrome

  19. COL4A1 mutation

  20. Hypoxic-ischemic injury

  21. Diabetes: diabetes mellitus, type 1 (DM, type 1), diabetes mellitus type 2 (DM, type 2), steroid-induced diabetes, gestational diabetes mellitus (GDM)

  22. Obesity

Specimen types:

  1. Brain tissues
  2. Meninges
  3. Choroid plexus
  4. Whole blood
  5. Serum
  6. Plasma
  7. Fibroblasts

As the leading global cause of disability, human brain disorders are a complex and multi-dimensional burden across generations. There is a critical gap for effective translation between discovery and therapeutics for human brain disorders. 

First funded in 2017, the Iowa NeuroBank Core is exploring new resources to support the communities as the only brain biorepository in Iowa. It serves neuroscientists by banking a wide range of biospecimens, including standardized, high-quality samples from more than 200 participants and 10 studies. Sample types at NeuroBank core include human brain tissue,  human fibroblasts, and human body fluids. In order to ensure that researchers have the most accurate information, the NeuroBank Core will provide the researcher with the most current information when you submit the tissue request forms.

Made possible through a generous gift by the Roy J. Carver Charitable Trust, the Iowa NeuroBank Core is a collaborative effort of the Iowa Neuroscience Institute and Departments of Pathology, Neurology, Psychiatry, Neuroscience, and Pharmacology at the University of Iowa to facilitate human brain research. This effort includes the support of NeuroBanking, NeuroRegeneration, and NeuroTech. 

Support us for human brain research in personalized medicine, including induced pluripotent stem cells (iPSCs) and genetic data for banked studies!