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Botox injection to salivary glands for hypersalivation

last modified on: Tue, 11/30/2021 - 11:55

See also: Ultrasound Guided FNA Fine Needle Aspiration BiopsyBotulinum neurotoxin treatment of salivary gland disorders;  (password protected) Botulinum neurotoxin infusion to the parotid via Stensen's duct Research protocol (IRB approved)

Video of onabotulinumtoxinA (Botox) infusion into left parotid gland with 25 gauge Chiba needleHypersalivation Ptyalism Sialorrhea

Botulinum Toxin Treatment for Sialadenitis (OnabotulinumtoxinA - Botox®) (IncobotulinumA - Xeomin®) and (AbobotulinumtoxinA - Dysport®) Salivary Swelling

Case #1 Hyper-salivation addressed with 4 gland Botox insufflation

Case #2 Excessive salivary flow from right parotid following cancer resection accumulating under intraoral flap reconstruction


Walter U and Dressler D: Ultrasound-guided botulinum toxin injections in neurology: technique, indications and future perspectives Expert Rev Neruothe. 2014 Aug;14(8):923-36

Cardona I, Mosseri A, Saint-Martin C, Daniel SJ: The Repetitive Usage of Onabotulinum Toxin type A into Savliary Glands for the management of Sialorrhea in the Pediatric Populatin: an Ultrasound Measurement.  Research Poster accessed on-line 6-28-2015 http://www.researchposters.com/Posters/COSM/COSM2015/H027.pdf

Petracca M, Guidubaldi A, Ricciardi L, Ialongo T, Del Grande A, Mulas D, Di Stasio E, Rita Bentivoglio A: Botulinum Toxin A and B in sialorrhea: Long-term data and literature overview.  Toxicon 107 (2015) 129-140

Schwalje AT, Hoffman HT. Salivary Gland Infusion With Botulinum Toxin.Laryngoscope Investig Otolaryngol. 2019 Sep 3;4(5):520-525. doi: 10.1002/lio2.306. eCollection 2019 Oct.

Ribeiro LB, Xerez DR, Maliska C, de Souza SAL, Costa MMB. Qualitative and quantitative scintigraphy in sialorrhea before and after botulinum toxin injection. Laryngoscope. 2019 Nov;129(11):2521-2526. doi: 10.1002/lary.27826. Epub 2019 Jan 28. PMID: 30693525.