Rainbo Hultman, PhD, assistant professor of molecular physiology and biophysics and a member of the Iowa Neuroscience Institute, is one of three winners of the 2021 Neurobiology of Brain Disorders Awards from the McKnight Endowment Fund.
A repurposed mouse model can develop symptoms of both severe COVID-19 (lung damage, blood clots, abnormal blood vessels, and death) and also of milder disease, including loss of the sense of smell, according to a new University of Iowa study published in Nature. When COVID-19 started spreading across the world earlier this year, UI researchers Stanley Perlman, MD, PhD, and Paul McCray, MD, realized that a mouse model they had created a decade earlier to study SARS might be an invaluable tool for understanding the concerning new disease and for testing potential treatments.
Eating a ketogenic diet rescued mice from heart failure, according to a recent study led by University of Iowa Carver College of Medicine researchers. The study, published online Oct. 26 ahead of the November issue of the journal Nature Metabolism, was one of three companion papers from independent research teams that all point to the damaging effects of excess sugar (glucose) and its breakdown products on the heart. The UI study, led by E. Dale Abel, MD, PhD, professor and chair of the Department of Internal Medicine, also revealed the potential to mitigate that damage by supplying the heart with alternate fuel sources in the form of high-fat diets.
A team of cystic fibrosis experts with University of Iowa Health Care has been awarded a five-year, $11.5 million grant by the National Heart, Lung, and Blood Institute to research molecular therapies for cystic fibrosis (CF) lung disease.