2024-2025
-
Zachary Knight, PhD
University of California San Francisco
Howard Hughes Medical Institutes
"Neural mechanisms that control appetite."
2023-2024
- Zhijian 'James' Chen, PhD
University of Texas Southwestern Medical Center
Howard Hughes Medical Institutes
"The enemy within - how does the immune system detect DNA as a danger signal from the interior of a cell?" - Beth Stevens, PhD
Harvard Medical School
Howard Hughes Medical Institutes
"Mapping Microglia States to Function in Development & Disease" - Charles S. Zuker, PhD
Columbia's Zuckerman Institute
"The Body-Brain Axis: From Sugare and Fat to Immunity" - Carrie Bearden, PhD
University of California, Los Angeles
"Pathways to Psychosis in Clinical and Genetic High Risk Youth"
2022-2023
- Chuan He, PhD
University of Chicago
Howard Hughes Medical Institute
“RNA Methylation in Gene Expression Regulation” - Paul Bieniasz, PhD
The Rockefeller University
Howard Hughes Medical Institute
"Antibodies versus SARS-CoV-2: Resisting Resistance" - William Hersh, MD, FACMI, FAMIA, FACP
Oregon Health & Science University School Medicine
"Translational Artificial Intelligence; The Need to Translate From Basic Science to Clinical Value"
2021-2022
- Lin Tian, PhD
University of California
Davis School of Medicine
"Watching the Brain in Action: Creating Tools for Functional Analysis of Neural Circuitry" - Akiko Iwasaki, PhD
Yale University
Howard Hughes Medical Institute
"Immune Responses to SARS-CoV-2" - Yi Zhang, PhD
Harvard Medical School
Howard Hughes Medical Institute
"Transcriptional Regulation: From Preimplantation to Innate Immunity"
2020-2021
- Vamsi Mootha, MD
Harvard Medical School
Massachusetts General Hospital
Howard Hughes Medical Institute
"Hypoxia as a Therapy for Mitochondrial Disease" - Christopher Walsh, MD, PhD
Harvard Medical School
Children's Hospital Boston
"One Braine, Many Genomes: Somatic Mutation and Genomic Diversity in the Human Brain from Development to Degeneration" - Pascale Cossart, PhD
Institut Pasteur
Académie des sciences
"Infection Biology in the Era of Microbiomes: The Listeria Paradigm"
2019-2020
- Gökhan Hotamisligil, MD, PhD
Harvard T.H. Chan School of Public Health
"The Metabolic Biology of the Endoplasmic Reticulum in Health and Disease" - Judith Campisi, PhD
Buck Institute for Research on Aging
"Cancer and Aging: Rival Demons" - Jeffrey Friedman, MD, PhD
The Rockefeller University
Howard Hughes Medical Institute
"Leptin and the Homeostatic Control of Food Intake and Body Weight" - Dana Carroll, PhD
Huntsman Cancer Institute
"Genome Editing: A View from the Edge"
2018-2019
- Mitchell A. Lazar, MD, PhD
University of Pennsylvania Perelman School of Medicine
"The Ups and Downs of Transcriptional Regulation of Metabolism" - Douglas Lowy, MD
National Cancer Institute, NIH
"Global Control of HPV-associated Cancers by Vaccination and Screening" - Eva Nogales, PhD
HHMI & University of California Berkeley
"Visualizing the molecular machinery in transcription initiation by cryo-EM" - Susan Amara, PhD
National Institute of Mental Health, NIH
"Dyamic regulation of signaling pathways in dopamine neurons: the intracellular actions of amphetamines" - Lily Jan, PhD
HHMI & University of California San Francisco
"The Enigmatic TMEM16 Family"
2017-2018
- James McNamara, MD
Duke University School of Medicine
"Neurotrophin Signaling and Epileptogenesis: Mechanistic and Therapeutic Insights" - C. Ronald Kahn, MD
Harvard Medical School
"Plasticity of Adipose Tissue and Its Communication in Metabolic Diseases" - Roger Kornberg, PhD
2006 Nobel Prize in Chemistry
"The Molecular Basis of Eukaryotic Transcription" - Paul Ridker, MD, MPH
Harvard Medical School
"Inflammation and Atherosclerosis: From Population Biology to the Bench to a Novel Treatment" - Duojia Pan, PhD
HHMI and University of Texas Southwestern Medical Center
"Hippo signaling in growth control and beyond"
2016-2017
- Wendell Lim, PhD
HHMI and University of California San Francisco
"Synthetic Biology: Learning to Talk to and Program Cells" - Robert Lefkowitz, MD
2012 Nobel Memorial Prize in Chemistry
Duke University School of Medicine
"Seven Transmembrane Receptors" - Barbara Kahn, MD
Harvard Medical School
"Discovery of a Novel Class of Mammalian Lipids with Anti-Diabetic and Anti-Inflammatory Effects" - Christine Seidman, MD
HHMI and Harvard Medical School
"Genetics of Cardiomyopathy: Getting to the Heart of the Matter" - Doris Tsao, PhD
HHMI and California Institute of Technology
"Face Perception: A Window into Visual Object Representation"
2015-2016
- Alvin Roth, PhD
2012 Nobel Memorial Prize in Economics
Stanford University
"Market Design and Medical Marketplaces" - Gail Mandel, PhD
HHMI and Oregon Health and Science University
"Repressor Mechanisms and Pathways to Disease - Keith Yamamoto, PhD
University of California San Francisco
"Molecular Signal Processing: From a Steroid Hormone, to Transcriptional Regulatory Networks, to Physiology and Disease, and Back"
"A NextGen Science Enterprise to Move Beyond the Inflection Point" - Angelika Amon, PhD
HHMI and Massachusetts Institute of Technology
"The Causes and Consequences of Aneuploidy"
2014-2015
- Steven McKnight, PhD
University of Texas Southwestern Medical Center
"A Solid State Conceptualization of Information Transfer from Gene to Message to Protein" - Ardem Patapoutian, PhD
The Scripps Research Institute and Novartis Research Foundation
"How Do You Feel? Ion Channels Involved in Sensing Mechanical Force" - Evan Eichler, PhD
HHMI and University of Washington
"Autism: New Mutations, Genes and Pathways Indentify Subtypes" - Marc Montminy, MD, PhD
Salk Institute for Biological Studies
"Can You Hear Me Now? Role of the CREB Pathway in Glucose Metabolism" - Eric Olson, PhD
University of Texas Southwestern Medical Center
"The Molecular Pathways of Muscle Development, Disease and Regeneration" - Stanley Hazen, MD, PhD
Cleveland Clinic
"Gut Microbes as a Participant in and Therapteutic Targe for Cardiometabolic Diseases"
2013-2014
- Charles Esmon, PhD
Oklahoma Medical Research Foundation
"The role of the protein C pathway and histones in the control of coagulation and inflammation" - Kristi Anseth, PhD
University of Colorado Boulder
"Hydrogels as Mimics of the Extracellular Matrix: Applications in Cell Biology and Tissue Regeneration" - Beth Levine, MD
University Texas Southwestern Medical Center
"Autophagy: Regulation, Physiological Functions, and Roles in Disease" - Carolyn Bertozzi, PhD
University of California Berkeley
"Bioorthogonal Chemistry: From Mechanism to Chemistry" - Samuel Silverstein, MD
Columbia University
"A critical Concentration of effector leukocytes is required to produce sterilizing immunity vs. bacterial and viral infection and cancer" - David Perlmutter, MD
University of Pittsburgh
"The Role of Autophagy in Diseases Caused by Misfolded Proteins: Alpha-1-Antitrypsin Deficiency as Prototype"
2012-2013
- Gregory Petsko, DPhil
Weill Cornell Medical College
"Specific Inhibition of Alpha-Synuclein Aggregation as a Therapeutic Strategy for Parkinson's Disease" - James N. Weinstein, DO, MS
Dartmouth-Hitchcock Health Care System
Lebanon Spine Center
"Creating a Sustainable Health Care System: Are You Ready?" - Susan Dymecki, MD, PhD
Harvard Medical School
"Toward Decoding the Brain Serotonergic System: Intersectional Genetics and Functional Probing" - Helen H. Hobbs, MD
University of Texas Southwestern Medical Center
"Nature, Nurture and Fatty Liver Disease" - Stuart A. Lipton, MD, PhD
Sanford Burnham Medical Research Institute
"Protein S-Nitrosylation, Redox Stress and NMDA Receptors in Alzheimer's and Parkinson's Diseases"
2011-2012
- C. Ronald Kahn, MD
Harvard University
"Role of Diabetes in Control of Brain Cholesterol Metabolism and Function" - David E. Clapham, MD, PhD
Harvard University
"Novel Ion Channels" - Jay C. Dunlap, PhD
Dartmouth University
"Genetic and Molecular Dissection of a Simple Circadian System" - Beverly S. Mitchell, MD
Stanford University
"Bone Marrow Failure Syndromes Revisted: Therapeutic Implications" - Michael Good, MBBS, PhD, MD, DSc
Griffith University
"The Long Road to a Malaria Vaccine" - Stephen M. Strittmatter, MD, PhD
Yale University
"Cell Surface Interactions during Neurodegeneration and Neural Repair"
2010-2011
- Peter C. Doherty, PhD
University of Melbourne, Australia
"Killer Viruses & Killer T-Cells" - Nathaniel Heintz, PhD
The Rockefeller University
"Genetic Dissection of the Mouse Nervous System: Toward a 21st Century Brain Pharmacology" - Erin O'Shea, PhD
Harvard University
"Oscillations and Entrainment in a Three-Protein Circadian Clock" - Toren Finkel, MD, PhD
National Heart, Lung and Blood Institute
"Oxidants, Metabolism & Stem Cell Biology" - Fred H. Gage, PhD
Salk Institute for Biological Studies
"Neuroplasticity & Neurodiversity" - Harald zur Hausen, MD, DSc, MDs
German Cancer Research Centre
2008 Nobel Prize Recipient in Physiology or Medicine
"Perspectives of Tumorvirus Research"
2009-2010
- Randy N. Rosier, MD, PhD
University of Rochester
"Translational Research Journeys: From Bedside to the Bench in Skeletal Repair and Arthritis" - E. Peter Greenberg, PhD
University of Washington
"The Social Life of Bacteria" - Pietro DeCamilli, MD
Yale University
"Moelcular Mechanisms of Endocytosis" - C. David Allis, PhD
The Rockefeller University
"Beyond the Double Helix: Reading and Writing the Histone Code" - I. Sadaf Farooqi, PhD, FRCP
University of Cambridge
"Genetic, Molecular & Physiological Mechanisms Involved in Human Obesity" - Harry "Hal" Dietz, MD
Johns Hopkins University
"Marfan Syndrome & Related Disorders: From Molecules to Medicines" - Deepak Srivistava, MD
University of California, San Francisco
"Genetics and Stem Cell Biology in Heart Disease" - Hollis "Holly" Cline, PhD
Scripps Research Institute
"Building Brain Circuits"