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Listed below are a few of the start-ups and their Carver College of Medicine founders. Innovation occurs in every department, and often across departments within both the college and university. Departments represented below include Anesthesia, Biochemistry, Internal Medicine, Neurosurgery, Obstetrics and Gynecology, Ophthalmology and Visual Sciences, Orthopaedics and Rehabilitation, Pharmacology, Psychiatry, Radiation Oncology, and Radiology.

Advanced Biomedical Informatics

Founders: Hans Johnson, PhD; H. Jeremy Bockholt
Description: Enterprise informatics solutions for translational neurosciences

Advanced Endovascular Therapeutics

Founders: David Hasan, MD
Description: Stent coating to treat intracranial aneurysms without the need for plavix

Behavioral Diagnostics

Founder: Robert Philibert, MD, PhD
Description: Epigenetic approaches to drug testing for substance abuse as well as diagnosis of disease, consultation and psychiatric testing

Brain Image Analysis

Founder: Ronald Pierson
Description: High-performance assessment of imaging biomarkers for use in research and clinical trials

Direct Spinal Therapeutics

Founders: Matthew Howard, MD; Timothy Brennan, MD, PhD
Description: Medical device capable of controlling neural pathways within the spinal cord for pain relief, relief of spacticity and motor control


Founders: Michael Kienzle, MD
Description: Point of care continuing education

Cellular Engineering Technologies

Founder: Alan Moy
Description: A biotechnology tissue engineering company

Clipse Therapeutics

Founder: Max Baker, PhD
Description: Buccal drug delivery device

Direct Spinal Therapeutics

Founders: Matthew Howard, MD; Dan O'Connell
Description: Pain management novel device called I (Iowa) Patch System to be implanted in patients to alter the functions of the spinal cord


Founders: Christopher Adams, MD, PhD; Michael Welsh, MD
Description: Discovery and development of small molecules to prevent and treat skeletal muscle atrophy, obesity and diabetes

Exemplar Genetics

Founder: Michael Welsh, MD; David Stolz, MD, PhD
Description: Porcine models of human disease including cystic fibrosis

Eyeprint Prosthetics

Founder: Christine Sindt, OD
Description: Ocular prosthetics


Founders: Michael Abramoff, MD, PhD; James Folk, MD; Stephen Russell, MD; Vinit Mahajan, MD, PhD
Description: Automated disease detection for frontline care  


Founder: Kimberly Leslie, MD; Baoli Yang, MD; Kristina Thiel, PhD; Donghai Dai, MD, PhD
Description: Personalized medicine for cancer patients through long-term tumor preservation, genetic analysis and clinical decision support 


Founder: Junyi Xia, PhD; R. Alfredo Siochi, PhD
Description: Software solutions to automate treatment error detection and prevention in radiation oncology


Founder: Zhendong Jin, PhD
Description: Discovery and development of novel anticancer drugs

Integrated DNA Technologies (IDT)

Founder: Joseph Walder, MD, PhD
Description: World's largest oligonucleotide-based reagent company specializing in sequencing, gene silencing, expression, monitoring and mutation detection. IDT has over 700 employees and is headquartered in Coralville, Iowa with facilities in San Diego, California; Leuven, Belgium; and Singapore. 

Inverad Medical Technologies

Founder: Sandeep Laroia, MD
Description: Developing innovative medical devices for the modern medicine

iota Motion

Founders: Marlan Hansen, MD; Christopher Kaufmann
Description: Implantable medical device that enables remote advancement of cochlear implant electrode as hearing deteriorates over time

Iowa Approach

Founder: Steven Mickelsen, MD
Description: Development of medical devices needed to perform a pioneering catheter-based epicardial atrial fibrillation ablation procedure 


Founder: Randy Kardon, MD, PhD; Pieter Poolman, PhD
Description: Digital medical services, advice, monitoring, mitigation, and treatment of migraine, headache, photosensitivity, neurological, ocular and vision-related conditions

Medical Imaging Applications

Founder: Milan Sonka, PhD; Dan Liang, PhD
Description: Quantitative assessment tools for cardiovascular risk, atherosclerosis and osteoarthritis

Needle Eye Medical

Founder: Steven Mickelsen, MD
Description: Commercializing line-of-sight real-time imaging technology to reduce iatrogenic needle-stick complications, increase operator workflow efficiency, and improve patient satisfaction

Nuclease Probe Technologies

Founder: James McNamara, PhD
Description: Nucleic acid-based methods for rapidly detecting bacterial pathogens

Ohana Vaccines

Founder: David Lubaroff, PhD
Description: Prostate cancer vaccine

Predelix Medical

Founders: Gen Shinozaki, MD; John Cromwell, MD
Description: Delirium predication screening utilizing a simplified EEG device with spectrum density analysis algorithm


Founder: Ryan Flynn, PhD
Description: Development of a device for delivering highly localized radiation doses to prostate cancer patients that are sculpted to avoid sensitive healthy tissues


Founders: Michael Henry, PhD; Sarah Vigmostad; Mike Cable
Description: Instrument to isolate and evaluate cancer cells

Talee Bio

Founders: Michael Welsh, MD; John F Engelhardt, PhD; Joseph Zabner, MD; Paul McCray, MD; Beverly Davidson, PhD
Description: Cystic Fibrosis Gene Therapy

Tansna Therapeutics

Founder: Max Baker, PhD
Description: Drug discovery and development for the treatment of seizures resulting from epilepsy or other central nervous system conditions

Terpenoid Therapeutics

Founder: Raymond Hohl, MD, PhD; David Wiemer, PhD
Description: Drug discovery and development targeting sterol metabolism for cancer therapy

VIDA Diagnostics

Founders: Eric Hoffman, MD, PhD; Geoffrey McLennan, MBBS, PhD; Milan Sonka, PhD; Joseph Reinhardt, PhD
Description: Quantitative pulmonary image analysis

Viewpoint Molecular Targeting

Founders: Michael Schultz, PhD; Frances Johnson, MD
Description: Development of injectable radio-pharmaceuticals for diagnosis and therapy for cancer, with focus on metastatic melanoma