New Funding Awards

Includes new, competitive renewal and supplemental awards.

2020: January, February, March, April, May, June, July, August
2019: January, February, March, April, May, June, July, August, September, October, November, December 
2018: January, February, March, April, May, June, July, August, September, October, November, December
2017: May, June, July, August, September, October, November, December

JUNE 2020

PI	Department	Sponsor	Title
Abreu, Alison Cornelia	Psychiatry	US Department of Health & Human Services, Health Resources & Services Administration	University of Iowa Hospitals and Clinics Addiction Medicine Fellowship Program
Alambert, Renata Pereira	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	The role of the integrated stress response in brown adipose tissue-mediated metabolic adaptations
Boudreau, Ryan Lee	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	The physiologic and genomic relevance of mitoregulin in ischemic heart failure
Comellas, Alejandro	Internal Medicine	Novartis Pharmaceuticals Corporation	Phase 3 multicenter, randomized, double-blind, placebocontrolled study to assess the efficacy and safety of canakinumab on cytokine release syndrome in patients with COVID-19-induced pneumonia (CAN-COVID)
Menda, Yusuf	Radiology	Advanced Accelerator Applications USA, Inc.	Phase I/II Trial of Peptide Receptor Radiotherapy (PRRT) with 177Lu-DOTA-tyr3-Octreotate (177Lu-DOTATATE) in Children with Neuroendocrine tumor, Neuroblastoma, or Pheochromocytoma/Paraganglioma. Dosimetry guided PRRT with 177Lu-DOTATATE in Children
Radoshevich, Lilliana	Microbiology	US Department of Health & Human Services, National Institutes of Health	Discovery of Novel Mechanisms of Action of Ubiquitin-Like Proteins in Cellular Stress Pathways
Sanchez, Antonio Jaime	Internal Medicine	ICON Clinical Research, LLC	A PHASE 2b RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY EVALUATING SAFETY AND EFFICACY OF EDP-305 IN SUBJECTS WITH LIVER-BIOPSY PROVEN NON-ALCOHOLIC STEATOHEPATITIS (NASH)
Spitz, Douglas Robert	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Training Program in Free Radical and Radiation Biology
Wadas, Thaddeus J Tgrasfer	Radiology	US Department of Health & Human Services, National Institutes of Health	PET Imaging of the Tumor Microenvironment for Cancer Detection
Wessel, Jan Reinhold	Neurology	US Department of Health & Human Services, National Institutes of Health	The role of cortical and subcortical beta-bursts in the cognitive control of human movement
Winokur, Patricia Lee	Internal Medicine	Pfizer, Inc.	SARS-CoV-2 RNA Vaccine Candidates Against COVID-19 in Healthy Adults
Young, Samuel Matthew	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Regulation of Synaptic Vesicle Dynamics in the Auditory System

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MAY 2020

PI	Department	Sponsor	Title
Ahrens, Richard C	Pediatrics	Perrigo New York, Inc.	Start-Up Agreement for Protocol PGR-NY-18-005
Bennion, Douglas Martin Foggia, Megan	Otolaryngology - Head & Neck Surgery	American Neurotology Society	Durable Zwitterionic Thin Film Coatings of Cochlear Implant Biomaterials
Correa, Tatiana	Otolaryngology - Head & Neck Surgery	American Neurotology Society	Comparison of Surgical Routes for Localized Inner Ear Viral Vector-Mediated Gene Therapy in the Guinea Pig Using Helper-Dependent Adenovirus Type 5
Dolan, Lori Ann Garwood	Orthopaedics and Rehabilitation	Boston Orthotics and Prosthetics	Boston Orthotics and Prosthetics
Femino, John	Orthopaedics and Rehabilitation	American Orthopaedic Foot & Ankle Society	A multifunctional implant that induces bone regeneration in diabetics
Fredericks, Douglas Christian	Orthopaedics and Rehabilitation	Theradaptive, Inc.	Theradaptive SOW 3:  Histology for Theradaptive Osteochondral Plug in a Rabbit
Gilbertson-White, Stephanie Seaman, Aaron Todd	Internal Medicine	American Cancer Society	Oncology Associated Stress & Individualized Support: AYA Feasibility Study
Henry, Michael Darrin	Molecular Physiology & Biophysics	Iowa State University	Parallel Selective Capture of Single Circulating Melanoma Cells and Integrated On-Chip Determination of Mutational Status
Hoffman, Eric Alfred	Radiology	Brigham and Women's Hospital	Immunometabolic phenotypes in adult severe asthma and disease progression
Hunter, Stephen Kieth Santillan, Donna A Elson, Marygrace Stockdale, Colleen Kennedy	Obstetrics & Gynecology	Iowa Department of Public Health	University of Iowa Obstetrics & Gynecology Rural Track Residency
Law, Ian Harry	Pediatrics	Abbott Laboratories	Advanced Training in Pediatric Cardiac Electrophysiology
Leslie, Kimberly Kay	Obstetrics & Gynecology	Iowa Department of Public Health	University of Iowa Obstetrics & Gynecology Rural Track Residency
Maury, Wendy	Microbiology	Furst-McNess Company	In vitro investigation into the influence of Furst-McNess nutritional supplement blend of alpha monoglycerides, botanical and essential oil against SARS-Coronavirus-2 in cell culture model
Michaelson, Jacob J	Psychiatry	Oregon Health & Science University	Integrating germline and mosaic mutations to uncover novel autism risk genes and biologic mechanisms
Mohr, Nicholas Matthew	Emergency Medicine	OLIVE VIEW-UCLA EDUCATION & RESEARCH INSTITUTE	COVID Evaluation of Risk for Emergency Departments (COVERED) Project
Porayette, Prashob	Pediatrics	Siemens Medical Solutions USA, Inc.	Siemens and Hospital for Sick Children Pulse Sequence and Image Reconstruction
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	COG - AALL1521
Schlievert, Patrick Michael	Microbiology	National Jewish Health	Atopic Dermatitis Research Network Leadership Center
Sharathkumar, Anjali Alatkar	Pediatrics	Hemophilia Alliance Foundation	Hemophilia Treatment Center Home Medical Binders/Educational Materials
Shy, Michael E	Neurology	Alnylam Pharmaceuticals, Inc.	Alnylam ALN-TTR02-012
Takacs, Michael Edward	Emergency Medicine	Iowa Department of Public Safety, State Fire Marshal	The burden of firework-related blast injuries from July 2015 to January 2020 within the two Level 1 trauma centers in Iowa
Thoma, Theodosia	Pediatrics	Novartis Pharmaceuticals Corporation	NOVARTIS Managed Access Program (MAP) Letter of Agreement (LoA) for BYL719 (Alpelisib) (Piqray)
Thomas, Christie	Internal Medicine	Regents of the University of Minnesota	Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant
Tran, Huy T T	Internal Medicine	Allakos, Inc.	A Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AK002 in Adult and Adolescent Patients with Active Eosinophilic Esophagitis
Vigil Gonzales, Carlos Enrique	Internal Medicine	Novartis Pharmaceuticals Corporation	Treatment Plan [CABL001A02001I]
Wattiez, Anne-Sophie	Molecular Physiology & Biophysics	Migraine Research Foundation	Efficacy and safety of CBD:THC combinations in migraine-like symptoms in mice
Wellnitz, Kari Aline	Pediatrics	University of Pennsylvania	PROSpect: PRone and OScillation PEdiatric Clinical Trial

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APRIL 2020

PI	Department	Sponsor	Title
Abel, Evan Dale	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	OPA1 an Estrogen-Mediated Modulator of Platelet Hyperactivation
Stone, Edwin M	Ophthalmology & Visual Sciences	US Department of Health & Human Services, National Institutes of Health	CRISPR/Cas9-mdiated correction of mutations that cause inherited retinal degenerations
Cadaret, Linda Marie	Internal Medicine	PhaseBio Pharmaceuticals, Inc.	A Long-Term, Open label Extension Study of PB1046 Subcutaneous Injections in Pulmonary Arterial Hypertension Subjects Following Completion of Study PB1046-PT-CL-0004
Cho, Josalyn Leah Olsen	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Regulation of the host immune response to influenza by the checkpoint receptor Tim3
DeMali, Kris A.	Biochemistry	US Department of Health & Human Services, National Institutes of Health	Molecular Mechanisms Underlying E-cadherin Mechanotransduction
Evans, Lucy Pratt	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Dissection and manipulation of inflammatory pathways underlying post-traumatic visual outcomes
Ferri, Sarah L	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Mechanisms of male-specific amygdala-dependent deficits in approach and avoidance behaviors
Hasan, David	Neurosurgery	US Department of Health & Human Services, National Institutes of Health	Neurocognitive Impairment Assessment in Symptomatic Carotid  Occlusion Recanalized Endovascularly: NIA SCORE
Leslie, Kimberly Kay	Obstetrics & Gynecology	US Department of Defense, Congressionally Directed Medical Research Program	OC190352 Converting Mutant p53 into an Actionable Target for the Treatment of Ovarian Cancer
Rhodes, Troy Edward	Internal Medicine	Milestone Pharmaceuticals, Inc.	Multi-Centre, Multi-National, Open Label, Safety Study of Etripamil Nasal Spray for Patients with Paroxysmal Supraventricular Tachycardia
Sabharwal, Rasnapreet	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Stress-induced cardiovascular dysfunction in dilated cardiomyopathy
Stephens, Samuel Brandon	Internal Medicine	US Department of Defense, Congressionally Directed Medical Research Program	PR190353 Exhausted protein sorting capacity impairs beta-cell function in Type 2 diabetes
Tucker, Budd Albert Stone, Edwin M	Ophthalmology & Visual Sciences	US Department of Health & Human Services, National Institutes of Health	CRISPR/Cas9-mdiated correction of mutations that cause inherited retinal degenerations
Vikas, Praveen	Internal Medicine	Sanofi US Services Inc.	ACT16105:  An open-label randomized Phase 2 trial of SAR439859, vs endocrine monotherapy as per physician's choice in premenopausal and postmenopausal patients with ER+, HER2-negative locally advanced or metastatic breast cancer with prior exposure to hor
Wadas, Thaddeus J	Radiology	US Department of Defense, Congressionally Directed Medical Research Program	W81XWH-19-1-0046/A Targeted Alpha Particle Radiopharmaceutical for Bone Metastatic Breast Cancer

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FEBRUARY 2020

PI	Department	Sponsor	Title
Abrams, Thad Eugene	Internal Medicine	US Department of Veterans Affairs	VA IPA for Brian Dake
Aldoss, Osamah	Pediatrics	Emory University	Long-term Outcomes after Interventions for Congenital Heart Disease
Allen, Bryan Golden	Radiation Oncology	Galera Therapeutics, Inc.	GTI-4419-203: A Phase 2a Open-Label Trial of the Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis in Subjects Receiving Chemoradiotherapy for Lung Cancer
Allen, Lee-Ann	Internal Medicine	US Department of Veterans Affairs	Dysregulation of the inflammatory response by Francisella tularensis
Bergkamp, Sarah M	Orthopaedics and Rehabilitation	Mid-America Orthopaedic Association	Mid-America Orthopaedic Association Education Grant
Bishop, Gail A	Microbiology	US Department of Health & Human Services, National Institutes of Health	Loss of TRAF3 in aging B lymphocytes
Bobb, Morgan R	Emergency Medicine	US Department of Health & Human Services, National Institutes of Health	The Role of Neighborhood- and Facility-Level Factors in Pediatric Sepsis Mortality
Boes, Aaron Daniel	Pediatrics	Sidney R. Baer, Jr. Foundation	Establishing a Neuromodulation/Neuropsychiatry Fellowship
Chegondi, Madhuradhar	Pediatrics	Ann & Robert H. Lurie Children's Hospital of Chicago	A Data-Driven Analysis of Pediatric Organ Dysfunction Patterns to Discover Sepsis Phenotypes
Cho, Christine	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Study of Neisseria gonorrhoeae adaptability to impact microbial survival and host response inside human neutrophil phagosomes
Compton, Jocelyn Traina	Orthopaedics and Rehabilitation	Mid-America Orthopaedic Association	Mid-America Orthopaedic Association Education Grant
Erickson, Bradley Allan	Urology	Boston Scientific Corporation	2020-2021 Genitourinary Reconstructive Urology Fellowship
Fredericks, Douglas Christian	Orthopaedics and Rehabilitation	OrthoRebirth Co. Ltd.	ReBOSSIS in a Lapine Posterolateral Fision Model and ReBOSSIS Bone Void Filler in a Rabbit Metaphyseal Defect Model
Garje, Rohan	Internal Medicine	Pfizer, Inc.	B9991040:  A Phase 1b/2 Study to Evaluate Safety and Clinical Activity of Avelumab in Combination with Bempegaldesleukin (NKTR-214) with or without Talazoparib or Enzalutamde in Participants with Locally Advanced or Metastatic Solid Tumors (JAVELIN IL-2 M
Haim, Hillel	Microbiology	American Foundation for AIDS Research	Deep learning methods to personalize antibody therapeutics for delaying viral rebound after cessation of ART
Hall, Mederic Micah Chimenti, Ruth	Orthopaedics and Rehabilitation	American Medical Society for Sports Medicine	Safety of ultrasound-guided tenotomy for Achilles tendinopathy and feasibility of a standardized ultrasound imaging protocol, a multi-site study
Hammond, Donna L	Anesthesia	V Foundation for Cancer Research	Alleviation of Paclitaxel-Induced Peripheral Neuropathies in Cancer Survivors
Harty, John Badovinac, Vladimir	Microbiology	US Department of Health & Human Services, National Institutes of Health	Memory CD8 T cell localization and protection from influenza
Hoffman, Eric Alfred	Radiology	University of Kansas Medical Center	Precision Biologic Interventions for Severe Exacerbation Prone Asthma (PrecISE)
Jabbari, Ali	Dermatology	Cutaneous Lymphoma Foundation	Extrapolating single cell RNA-seq analysis of Sezary syndrome to other cutaneous lymphomas
Kaczka, David Walter	Anesthesia	The General Hospital Corporation, Massachusetts General Hospital	PET/CT-Guided Personalized Mechanical Ventilation to Minimize Ventilator-Induced Lung Injury
Kenny, Colin Patrick	Anatomy & Cell Biology	American Association of Anatomists	A model of Kctd15 regulation of Tfap2 in neural crest specification
Killoran, Annie	Neurology	ACADIA Pharmaceuticals	A Pilot Randomized, Double-blind, Placebo-controlled Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson's Disease Treated With Pimavanserin or Low Dose Quetiapine
Kline, Joel N	Internal Medicine	AstraZeneca LP	A Phase 4, Multicenter, Randomized, Double-blind, Parallel Group, Placebo Controlled Study to Evaluate the Effect of Benralizumab on Structural and Lung Function Changes in Severe Eosinophilic Asthmatics (CHINOOK)
Krysan, Damian Joseph	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis
Lentz, Steven	Internal Medicine	Novo Nordisk, Inc.	Explorer 8
Lentz, Steven	Internal Medicine	Versiti Wisconsin, Inc.	Zimmerman Program on the Biology of VWD
Mathews, Katherine Dianne	Pediatrics	Retrotope, Inc.	A RANDOMIZED, DOUBLE-BLIND, CONTROLLED, PHASE 2/3 STUDY
Mathews, Katherine Dianne	Pediatrics	Catabasis Pharmaceuticals	An Open-Label Extension Study of Edasalonexent in Pediatric Patients with Duchenne Muscular Dystrophy
McCray, Paul B	Pediatrics	Medical College of Wisconsin	Base editing in the Rhesus airway epithelia
Meier, Jeffery Linn	Internal Medicine	US Department of Veterans Affairs	Mechanisms regulating cytomegalovirus
Nopoulos, Peggy Colleen	Psychiatry	Novartis Pharma AG	JHD advisory Board
O'Donnell, Michael A	Urology	Vaxiion Therapeutics	Phase I Safety and Tolerability of Intravesical VAX014 for Instillation in Subjects with Non-Muscle Invasive Bladder Cancer (NMIBC)
Pugely, Andrew	Orthopaedics and Rehabilitation	Globus Medical, Inc.	The Modular Pedicle Screw System: A Safe and Effective System to Correct Deformity
Sahar, Nadav	Internal Medicine	Kangen Pharmaceuticals America, LLC	A PHASE 1, SINGLE DOSE PK AND SAFETY STUDY WITH NI-03 FOLLOWED BY A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP DOSE-RANGING STUDY TO EVALUATE THE SAFETY AND EFFICACY OF NI-03 COMPARED TO PLACEBO IN SUBJECTS WITH CHRONIC PANCREATITIS
Scott, Elizabeth Joy	Orthopaedics and Rehabilitation	Ruth Jackson Orthopaedic Society	Assessment of Disability Related to Hip Dysplasia Using Objective Measures of Physical Performance
Strouse, Christopher	Internal Medicine	Lymphoma Research Foundation of America, Inc.	Comparative Effectiveness Research Strategies Assessing Bendamustine Dosing in Follicular Lymphoma
Sugg, Sonia	Cancer Center	University of Wisconsin-Madison	Phase 1b 9cUAB30 in Early Stage Breast Cancer to Evaluate Biologic Effect
Tranel, Daniel Thomas	Neurology	Kiwanis Neuroscience Research Foundation (Spastic Para Rsch Fdn)	Neuropsychological interventions for improving health and quality of life in persons with Alzheimer's disease and their caregivers
Van Heukelom, Paul Gary	Emergency Medicine	Inflammatix, Inc.	HostDX Sepsis in the Diagnosis and Prognosis of Emergency Department Patients with Suspected Infections and Suspected Sepsis
Vaughan Sarrazin, Mary Susan	Internal Medicine	US Department of Veterans Affairs	Use and Outcomes of Obesity Treatment Programs Among Rural Veterans With Obesity
Vyas, Yatin Mahendra	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Mechanisms of R loop-mediated genome instability in Wiskott-Aldrich syndrome
Wall, Michael	Ophthalmology & Visual Sciences	Hoffmann-La Roche, Inc.	VFRC Roche-RO6868847 IN DIABETIC RETINOPATHY (DR)
Wibbenmeyer, Lucy A	Surgery	MediWound Ltd.	Use of NexoBrid for Treatment of Acute deep partial and full thickness Burn Injuries,
Wilkinson, Brandon Garth	Orthopaedics and Rehabilitation	Mid-America Orthopaedic Association	Mid-American Orthopaedic Association  Education Grant
Winokur, Patricia Lee	Internal Medicine	Duke University	Collaborative Influenza Vaccine Innovation  Centers (CIVICs) - CIVICs Component C
Wu, Li	Microbiology	US Department of Health & Human Services, National Institutes of Health	SAMHD1-mediated regulation of HIV-1 innate immunity and viral gene expression

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DECEMBER 2019

PI	Department	Sponsor	Title
Abel, Evan Dale	Diabetes Research Center	Rivus Pharmaceuticals, Inc.	Promethion and PK Arm
Alambert, Renata Pereira	Internal Medicine	State University of New York Research Foundation	Program to Increase Diversity in Cardiovascular Health-Related Research (PRIDE-CVD)
Alvarez, Paulino	Internal Medicine	MyoKardia, Inc.	MAVA-LTE
Bishop, Gail A	Microbiology	Intima Capital, LLC	Intima Capital Laboratory Work
Boes, Aaron	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Predicting Cognitive Outcomes from Stroke Based on Lesion Location
Calhoun, Amy	Pediatrics	Ultragenyx Pharmaceutical Inc.	Emergency Compassionate Use of triheptanoin in a patient with VLCAD deficiency
Folk, James C	Ophthalmology & Visual Sciences	Johns Hopkins University	Adalimumab vs. conventional immunosuppression for uveitis (ADVISE) Trial
Fortis, Spyridon	Internal Medicine	Fisher & Paykel Healthcare	The effect of heated, humidified high-flow air in COPD patients with chronic bronchitis
Fredericks, Douglas	Orthopaedics and Rehabilitation	Zimmer Biomet Holdings, Inc.	A Pilot Evaluation of Nano-coating Interbody Spacers in a Sheep Lumbar Interbody Fusion Modal
Furqan, Muhammad	Internal Medicine	AstraZeneca LP	A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab Following Stereotactic Body Radiation Therapy (SBRT) for the Treatment of Patients with Stage I/II Non-small Cell Lung Cancer (PACIFIC-4 / RTOG-3515
Harty, John Badovinac, Vladimir	Microbiology	US Department of Health & Human Services, National Institutes of Health	Memory CD8 T cell localization and protection from influenza
Kumar, Ashok	Neuroscience and Pharmacology	American Heart Association	Neurogenic Mechanisms of Obesity-Induced Hypertension
Larson Ode, Katie Marie	Pediatrics	Regents of the University of Minnesota	EnVision Chair
Milhem, Mohammed	Internal Medicine	Immunocore Limited	A Phase I/II Open-label, Multi-center Study of the Safety and Efficacy of IMCnyeso, an HLA- A*0201-Restricted, NY-ESO-1- and LAGE-1A-specific Soluble T Cell Receptor and Anti-CD3 Bispecific Molecule, as a Single Agent in HLA-A*0201 Positive Patients with
Murray, Jeffrey	Pediatrics	Emory University	Genetic modifiers of Van der Woude syndrome
Nester, Carla	Pediatrics	Novartis Pharmaceuticals Corporation	An open-label, non-randomized extension study to evaluate the long-term efficacy, safety and tolerability of LNP023 in subjects with C3 glomerulopathy
O'Neill, Brian	Internal Medicine	US Department of Veterans Affairs	VA IPA for Christie Penniman
Polgreen, Philip	Internal Medicine	US Department of Veterans Affairs	An M-Health Intervention to Increase the Activity Levels of Rural Veterans (Maptrek)
Richerson, George B	Neurology	University of Texas Health Science Center at Houston	Autonomic and imaging biomarkers of SUDEP
Rouault, Alix	Molecular Physiology & Biophysics	American Heart Association	Mechanism and physiological role of MRAP2-mediated regulation of GHSR1a signaling
Russell, Stephen R	Ophthalmology & Visual Sciences	ProQR Therapeutics B.V.	ProQR PQ-110-003 LCA Study
Shaban, Amir	Neurology	University of Cincinnati	Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE) StudyN
Sun, Xingshen	Anatomy & Cell Biology	University of Southern California	High throughput screening to maintain pluripotent ferret iPSC for use in pre-clinical autologous cell therapy models
Tamplin, Michelle	Internal Medicine	American Heart Association	AHA: Quantitating vascular-mediated normal tissue injury with non-invasive imaging methods
Tanas, Munir-Zakary	Pathology	US Department of Health & Human Services, National Institutes of Health	Epigenetic modulation of the TAZ-CAMTA1 transcriptional program by the Ada2a-containing histone acetyltransferase complex
Uc, Ergun Y	Neurology	Parkinson's Foundation	Parkinson's Foundation Patient Centered Outcomes Research Institute (PCORI) Award Collaboration
Vigil Gonzales, Carlos	Internal Medicine	Tolero Pharmaceuticals, Inc.	A Phase 1b/2, Open-label Clinical Study to Determine Prelinary Safety and Efficacy of Alvocidib When Administered in Sequence After Decitabine in Patients with MDS
Vigil Gonzales, Carlos	Internal Medicine	Washington University in St. Louis	An open label, multicenter, phase II trial testing single agent decitabine in TP53 mutated relapsed / refractory acute myeloid leukemia
Willour, Virginia	Psychiatry	American Foundation for Suicide Prevention	An Integrated Approach to Understanding the Biology of Suicidal Behavior
Wilson, Mary E	Internal Medicine	US Department of Veterans Affairs	Innate inflammatory cells in leishmaniasis.
Zakharia, Yousef	Internal Medicine	University of Michigan	Biomarker-Based Decision Support Tools for Treatment Response of Bladder Cancer
Zhao, Chen	Pathology	US Department of Health & Human Services, National Institutes of Health	Heat Shock Transcription Factor 1 Specifically Regulates AML Stem Cell Self-Renewal
Zhu, Eliot	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Drivers of MAPK-redundant resistance to BRAF inhibition in melanoma

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NOVEMBER 2019

Forthcoming

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OCTOBER 2019

PI	Department	Sponsor	Title
Ahern, Christopher A	Molecular Physiology & Biophysics	Oregon Health & Science University	Probing functional mechanisms in K+ channels using unnatural mutagenesis
Ahern, Christopher A	Molecular Physiology & Biophysics	Thomas Jefferson University	Mining the tRNA genome by live-cell imaging
Ahrens, Richard C	Pediatrics	Vertex Pharmaceuticals, Inc.	A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Who Are Heterozygous for the F508del Mutation and a Gating or Residual Function Mutation
Assouline-Dayan, Yehudith	Internal Medicine	Arena Pharmaceuticals, Inc.	A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of Olorinab in Subjects with Irritable Bowel Syndrome Experiencing Abdominal Pain
Bender, David Paul	Obstetrics & Gynecology	TESARO, Inc.	GOG-3031/ 4010-03-001/ RUBY
Bernat, John	Pediatrics	BioMarin International Limited	MARS Registry
Bernat, John	Pediatrics	Shire Human Genetic Therapies, Inc.	A Global, Multicenter, Open-Label, Matched Historical Control Study of Intrathecal SHP611 in Subjects with Late Infantile Metachromatic Leukodystrophy (MLD)
Cadaret, Linda	Internal Medicine	Complexa, Inc.	PRIMEx
Comellas, Alejandro	Internal Medicine	AstraZeneca Pharmaceuticals LP	The CHRONICLE Study: A Longitudinal Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States
Dickens, David	Pediatrics	Children's Hospital of Philadelphia	Workload Intensity Model for Support for Study Chairs: NCORP Research Base Grant UG1CA189955
Fuentes, Ernesto J	Biochemistry	University of Colorado Denver	Regulation of Staphylococcus aureus colonization and disease
Furqan, Muhammad	Internal Medicine	Incyte Corporation	A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants with Previously Treated Locally Advanced / Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Ac
Hammond, Donna L	Anesthesia	Foundation for Anesthesia Education & Research	Joseph Stearns- FAER T35 Medical Student Travel Award
Hefti, Marco	Pathology	Pinteon Therapeutics, Inc.	Validation of a Novel Tau Antibody in a Porcine Model of Traumatic Brain Injury
Hefti, Marco	Pathology	Children's Hospital of Philadelphia	Biomedical Optical Devices to Monitor Cerebral Health
Jethava, Yogesh	Internal Medicine	Pfizer, Inc.	A Phase 1, Open Label Study to Evaluate the Safety, PKs, PDs and Clinical Activity of PF-06863135, a B-Cell Maturation Antigen (BCMA) - CD3 Bispecific Antibody, in Patients with Relapsed/Refractory Advanced Multiple Myeloma
Kuperman, Samuel	Psychiatry	State University of New York	Collaborative Study on the Genetics of Alcoholism (COGA)
Leira, Enrique	Neurology	University of Cincinnati	Strokenet: ARCADIA CSI (Cognition and Silent Infarcts)
Mathews, Katherine	Pediatrics	AveXis, Inc.	A Prospective, Long Term Registry of Patients with a Diagnosis of Spinal Muscular Atrophy (SMA)
Mathews, Katherine	Pediatrics	ML Bio Solutions, Inc.	ML Biosolutions Consulting
Milhem, Mohammed	Internal Medicine	Innovent Biologics, Inc.	An open-label, phase 1b multicenter study of IBI308 in subjects with advanced/metastatic solid malignancies
Milhem, Mohammed	Internal Medicine	Replimune, Ltd.	An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination with PD1 Blockade in Patients with Solid Tumors
Mills, James	Psychiatry	Baylor College of Medicine	Examining SSRI-Induced Disruption of Pubertal Growth Spurt
Nester, Carla	Pediatrics	Research Institute at Nationwide Children's Hospital	CUREGN 2.0 - Midwest Pediatric Nephrology Consortium - PCC
Pena, Tahuanty	Internal Medicine	Vertex Pharmaceuticals, Inc.	VX-445/TEZ/IVA Triple Combination Expanded Access Program for Patients 12 Years of Age and Older With Cystic Fibrosis Who Are Heterozygous for F508del and a Minimal Function CFTR Mutation
Philibert, Robert	Psychiatry	University of Georgia	Origin of Chronic Diseases of Aging Among Rural African American Young Adults
Richerson, George B	Neurology	US Department of Health & Human Services, National Institutes of Health	The role of central CO2 chemosensitivity in postictal respiratory depression and SUDEP
Samaniego, Edgar A	Neurology	Medtronic, Inc.	Education grant request to fund travel to the 17th Interdisciplinary Cerebrovascular Symposium (ICS 2020).
Samaniego, Edgar A	Neurology	Bee Foundation	Aneurysm Characterization with High-Resolution Vessel Wall Imaging
Samaniego, Edgar A	Neurology	Society of Vascular and Interventional Neurology	Aneurysm Characterization with High-Resolution Vessel Wall Imaging
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	Pediatric Match (APEC1621SC) PCR
Schieltz, Kelly	Pediatrics	University of Missouri	Show-Me ECHO Project
Schweizer, Marin	Internal Medicine	PDI Healthcare	Feasibility of Pre-operative Povidone Iodine Decolonization among Orthopedic Trauma Surgery Patients To Reduce S. aureus SSIs
Scott, Elizabeth	Orthopaedics and Rehabilitation	Journal of Bone and Joint Surgery	Robert Bucholz Resident Journal Club Grant Program
Shibbani, Kamel	Pediatrics	American Academy of Pediatrics	Understanding the role of steriod use in preterm infants who develop Post Ligation Cardiac Syndrome after surgical closure of Patent Ductus Arteriosus
Smith, Richard J	Otolaryngology - Head & Neck Surgery	Emory University	Endothelialized microfluidic model of atypical hemolytic uremic syndrome
Winokur, Patricia	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Vaccine and Treatment Evaluation Units (VTEU) Protocol Development and Implementation Task Area B-C Phase II Therapeutic Trial for Trichuris trichiura TASK ORDER 18-0004.B1C1.0121
Zakharia, Yousef	Internal Medicine	Pharmacyclics LLC	PCYC-1128-CA:  A Phase 1b/2 Study of Ibrutinib Combination Therapy in Selected Advanced Gastrointestinal and Genitourinary Tumors

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SEPTEMBER 2019

PI	Department	Sponsor	Title
Ahrens, Richard C	Pediatrics	AbbVie, Inc.	A Phase 4 Study to Compare Marketed Creon Drug Product with Drug Product Manufactured with a Modernized Process at an Alternate Manufacturing Site, in Subjects with EPI due to Cystic Fibrosis
Coryell, William H	Psychiatry	Allergan Sales, LLC	A double-blind, placebo-controlled study of cariprazine as an adjunct to antidepressants in the treatment of patients with major depressive disorder who have had an inadequate response to antidepressants alone
Engelhardt, John F	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	National Ferret Resource & Research Center on Lung Disease - Federal Contract
Fath, Melissa	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Repurposing redox active agents for exploiting differences in cancer cell metabolism for improving cancer therapy
Hagiwara, Yuya	Internal Medicine	US Department of Health & Human Services, Health Resources & Services Administration	Program Development and Educational Research in Geriatrics and Palliative Care
Heer, Collin	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Selective targeting of tumor cell redox metabolism and DNA damage responses to enhance cancer therapy
Hefti, Marco	Pathology	US Department of Health & Human Services, National Institutes of Health	Novel tau-based diagnostics for neonatal hypoxic-ischemic injury
Kreder, Karl Bradley, Catherine S	Urology	US Department of Health & Human Services, National Institutes of Health	University of Iowa LURN Research Site
Lin, Fang	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	The role of Glypican 4 in gut endoderm morphogenesis
Maddox, John	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Voltage-gated calcium channels in the development of photoreceptor synapses
McDowell, Bradley D	Cancer Center	US Department of Health & Human Services, National Institutes of Health	Building a patient-centered cancer data mart in a rural state
Milhem, Mohammed	Internal Medicine	Genentech, Inc.	BP41054: An Open-Label, Multicenter, Phase 1B Study to Evaluate Safety and Therapeutic Activity of RO6874271, an Immunocytokine, Consisting of IL-2 Variant Targeting Fibroblast Activation Protein-A, in Combination with Pembrolizumab, in Participants with
Nopoulos, Peggy	Psychiatry	US Department of Health & Human Services, National Institutes of Health	Growth and development of Striatal-Cerebellum circuitry in subjects at risk for Huntington's Disease
Polgreen, Philip  Miller, Aaron	Internal Medicine	US Department of Health & Human Services, Agency for Healthcare Research & Quality	An expert-guided machine-learning approach to estimate the incidence, risk and harms associated with diagnostic delays for infectious diseases.
Russo, Andrew F	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Target validation of a novel CGRP receptor in migraine
Sebag, Julien Albert	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Identification of the central localization and regulation of the Prokineticin 1 Receptor, a novel target for the treatment of obesity
Shy, Michael E	Neurology	Acceleron Pharma, Inc.	A083-04
Sluka, Kathleen A	Physical Therapy	US Department of Health & Human Services, National Institutes of Health	Fibromyalgia TENS in Physical Therapy Study (TIPS): an embedded pragmatic clinical trial
Wibbenmeyer, Lucy A	Surgery	Avita Medical Americas, LLC	A Prospective Multicenter Randomized Controlled Clinical Study to Investigate the Safety and Effectiveness of RES (Regenerative Epidermal Suspension) Prepared with the RECELL Device Compared to Conventional Care for Healing of Donor Sites in Infants, Chi
Zakharia, Yousef	Internal Medicine	Kyowa Kirin Pharmaceutical Development, Inc.	An Open-label, Phase 1 Study of KHK2455 in Combination with Avelumab in Adult Subjects with Locally Advanced or Metastatic Urothelial Carcinoma

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AUGUST 2019

PI	Department	Sponsor	Title
Boudreau, Ryan	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	The genomic interface of microRNA regulation and heart failure
Geyer, Pamela	Biochemistry	US Department of Health & Human Services, National Institutes of Health	The Role of LEM Domain Proteins in Nuclear Function
Glykys, Joseph	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Osmotic Therapy for Seizures in Pediatric Traumatic Brain Injury
Horwitz, Phillip	Internal Medicine	Boston Scientific Corporation	ACURATE IDE
Infield, Daniel	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Chemical Biology of CFTR Regulation
Jabbari, Ali	Dermatology	Pfizer, Inc.	Pfizer: B7981015: A PHASE 2B/3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF PF-06651600 IN ADULT AND ADOLESCENT ALOPECIA AREATA (AA) SUBJECTS WITH 50% OR GREATER SCALP
Kreder, Karl	Urology	US Department of Health & Human Services, National Institutes of Health	Urology Chronic Pelvic Pain Longitudinal Symptom Patterns Study
Laux, Douglas	Internal Medicine	Merck & Company, Inc.	A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants with High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE
Lee, Amy	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Illuminating the functions of CACNA2D4 in the brain
Leira, Enrique  Chauhan, Anil	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	The University of Iowa Stroke Preclinical Assessment Center for Neuroprotection in stroke
Miller, Delwyn	Psychiatry	University of Southern California	Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Open-Label Extension Study
Moye-Rowley, William	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Analysis of transcription factors determining azole resistance of Aspergillus fumigatus
Rangarajan Murali, Arvind	Internal Medicine	Arrowhead Pharmaceuticals, Inc.	A Placebo-Controlled, Multi-dose, Phase 2/3 Study to Determine the Safety, Tolerability and Effect on Liver Histologic Parameters in Response to ARO-AAT in Patients with Alpha-1 Antitrypsin Deficiency (AATD)
Schmidt, Warren	Internal Medicine	Allergan Sales, LLC	Open-label Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis (NASH)
Sebag, Julien Albert	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Identification of the central localization and regulation of the Prokineticin 1 Receptor, a novel target for the treatment of obesity
Shy, Michael E	Neurology	US Department of Health & Human Services, National Institutes of Health	The Inherited Neuropathy Consortium (INC) RDCRC- Overall
Shy, Michael E	Neurology	US Department of Health & Human Services, National Institutes of Health	Clinical Trial Readiness for Rare Diseases, Disorders and Syndromes
Sluka, Kathleen A Coffey, Christopher S Frey Law, Laura A	Physical Therapy	US Department of Health & Human Services, National Institutes of Health	Clinical Coordinating Center for the Acute to Chronic Pain Signatures Program

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JULY 2019

PI	Department	Sponsor	Title
Abel, Edwin G	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Mechanistic studies on the impact of sleep deprivation on gene regulation
Bishop, Gail A	Microbiology	US Department of Defense, Congressionally Directed Medical Research Program	CA180190P1 CD24 Tumor-Initiating Cell as a Novel Therapeutic Target in Myeloma
Boes, Aaron Daniel	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Investigating the Effects of Transcranial Magnetic Stimulation with Intracranial EEG in Humans
Brenner, Charles Michael	Biochemistry	ChromaDex, Inc.	Evaluating the Oral Bioavailability of NAD Boosters in the Brain
Brenner, Charles Michael	Biochemistry	Bill & Melinda Gates Foundation	Testing NAD Precursors as Galactagogues
Cornell, Robert A	Anatomy & Cell Biology	Massachusetts General Hospital	Genomic and Functional Analysis of IRF6 Target Genes in Orofacial Cleft Pathogenesis
Furqan, Muhammad	Internal Medicine	AstraZeneca Pharmaceuticals LP	A Phase IB, Open-Label, Multi-Center Study to Determine the Efficacy and Safety of Durvalumab in Combination With Novel Oncology Therapies, With or Without Chemotherapy, for First-Line Stage IV Non-Small Cell Lung Cancer (NSCLC) (MAGELLAN)
Gutmann, Laurie	Neurology	Expansion Therapeutics, Inc.	Double-Blind, Placebo-Controlled, Dose-Range-Finding, Crossover Trial of Single Day Administration of ERX-963 in Adults with Myotonic Dystrophy Type 1
Hoffman, Eric Alfred	Radiology	Washington University in St. Louis	Washington University's Precision Biologic Interventions for Severe Exacerbation Prone Asthma (PrecISE)
Infield, Daniel	Molecular Physiology and Biophysics	National Institutes of Health	Chemical Biology of CFTR Regulation
Leira, Enrique	Neurology	National Institutes of Health	The University of Iowa Stroke Preclinical Assessment Center for Neuroprotection in Stroke
Lentz, Steven	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Program in Hematology: Molecular & Cell Biology Blood Cells
Link, Brian Krall	Internal Medicine	AstraZeneca Pharmaceuticals LP	Treatment Patterns, Outcomes, and Patient-Reported Health-Related Quality of Life: A Prospective Disease Registry of Patients with Mantle Cell Lymphoma Treated with Novel Agents
Mathews, Katherine Dianne	Pediatrics	Sarepta Therapeutics	Long-term, Open-label Extension Study for Patients with Duchenne Muscular Dystrophy Enrolled in Clinical Trials Evaluating Casimersen or Golodirsen
Nizar, Jonathan	Internal Medicine	National Institutes of Health	Contribution of Renal Tubule Insulin Receptor on Proximal Tubule Sodium Transport and Hypertension in the Metabolic Syndrome
Smith, Richard J	Otolaryngology - Head & Neck Surgery	US Department of Health & Human Services, National Institutes of Health	Autosomal Dominant Non-Syndromic Hearing Loss - Its Genetic Diagnosis and Treatment
Stoltz, David A	Internal Medicine	Cystic Fibrosis Foundation	Iowa Cystic Fibrosis Foundation Research & Development Program
Vigil Gonzales, Carlos Enrique	Internal Medicine	Aprea Therapeutics	A Phase III Multicenter, Randomized, Open Label Study of APR-246 in Combination with Azacitidine vs Azacitidine Alone for the Treatment of TP53 Mutant Myelodysplastic Syndromes
Willock, Amy	Microbiology	Department of Defense, CDMRP	Regulation of the B cell receptor and B cell homeostasis by tumor necrosis factor receptor associated factor 3
Young, Samuel Matthew	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Development of Helper Dependent Adenoviral Vectors for Inner Ear Gene Therapy Approaches
Zakharia, Yousef	Internal Medicine	Exelixis, Inc.	Cabozantinib and Pembrolizumab as a Front Line Therapy for Advanced Melanoma
Zhan, Fenghuang	Internal Medicine	US Department of Defense, Congressionally Directed Medical Research Program	CA180190 CD24 Tumor-Initiating Cell as a Novel Therapeutic Target in Myeloma

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JUNE 2019

PI	Department	Sponsor	Title
Ahern, Christopher A	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Chemical Biology of Voltage-Gated Cation Channels
Ahrens, Richard C	Pediatrics	Aurobindo Pharma USA, Inc.	Master Service Agreement and SOW #1
Allen, Lee-Ann Harty, John	Microbiology	US Department of Health & Human Services, National Institutes of Health	Interdisciplinary Immunology Postdoctoral Training Program
Andersen, Allan Michael	Psychiatry	Behavioral Diagnostics, LLC	An integrated epigenetic ELISA saliva kit for detecting & quantifying both tobacco and nicotine use
Avner, Benjamin S	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Human neutrophil derived microvesicles modulate phagocyte activity
Bailin, Steven	Internal Medicine	Boston Scientific Corporation	INTERRUPT AF
Bollier, Matthew John	Orthopaedics and Rehabilitation	Smith & Nephew, Inc.	Univ. of Iowa Sports Medicine Fellowship
Chimenti, Ruth	Physical Therapy	US Department of Health & Human Services, National Institutes of Health	Mechanism-based treatment approach to chronic tendinopathy pain
Cho, Josalyn Leah Olsen	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Tim3 is a novel regulator of dendritic cell-T cell interactions in influenza
Derdeyn, Colin P	Radiology	Pulse Therapeutics, Inc.	Magnetically Enhanced Diffusion for Intra-Arterial (MEDIA) Treatment of Acute Ischemic Stroke
Doddapattar, Prakash	Internal Medicine	American Heart Association	Mechanistic role of integrin alpha9beta1 in atherosclerosis
Dunn-Johnson, Camille C	Otolaryngology - Head & Neck Surgery	MED-EL Corporation	Iowa Cochlear Implant Clinical Research Center Study of SSD using MED-EL Cochlear Implants
Eisenberg, Joshua Mark	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course - Trauma Basic Principles
Ford, Bradley	Pathology	JMI Laboratories	ANALYTICAL VALIDATION OF CLINICAL MICROBIOLOGY PROCEDURES
Fredericks, Douglas Christian	Orthopaedics and Rehabilitation	Globus Medical, Inc.	Assessment of Umbilical Cord Derived Stem Cells in a Rabbit Degenerative Disc Model
Furqan, Muhammad	Internal Medicine	AbbVie, Inc.	M17-327:  A Phase 1 Study of SC-011 as a Single-Agent and in Combination with ABBV-181 in Subjects with Relapsed or Refractory Small Cell Lung Cancer
Gakhar, Lokesh	Medicine Administration	Bonumose Biochem LLC	Crystallography project for Bonumose LLC
Geerling, Joel C	Neurology	Iowa Fraternal Order of the Eagles	Circuit-based treatments for hydrocephalic dementia with urinary incontinence
Gerke, Alicia	Internal Medicine	Biogen, Inc.	A Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of BG00011 in Patients With Idiopathic Pulmonary Fibrosis
Gordon, David Jon	Pediatrics	Fraternal Order of Eagles	Identification of Synergistic Drug Combinations Using a High-Throughput, Chemical-Genetic Screen
Grose, Charles	Pediatrics	University of Illinois at Urbana-Champaign	Role of gC Glycoprotein in transmission of avian and human herpes viruses
Gulbrandsen, Trevor Robert	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course - Trauma Basic Principles of Fracture Management
Gutmann, Laurie	Neurology	Virginia Commonwealth University	Myotonic Dystrophy Clinical Research Network (DMCRN) Multicenter Study of Natural History and Genetic Modifiers in Myotonic Dystrophy Type-1 (END-DM1)
Hamzeh, Nabeel Y	Internal Medicine	aTyr Pharma, Inc.	A Randomized, Double-Blind, Placebo-Controlled Multiple Ascending Dose Study of Intravenous ATYR1923 in Patients with Pulmonary Sarcoidosis
Kline, Joel N	Internal Medicine	inVentiv Health Clinical	A Long-term, Randomized, Double-blind, Multicenter, Parallel Group, Phase III Study Evaluating the Efficacy and Safety of PT027 Compared to PT007 Administered as Needed in Response to Symptoms in Symptomatic Adults and Children 4 Years of Age or Older wit
Kohler, James Gilweit	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course - Trauma Basic Principles
Kohlmeyer, Jordan Lynn	Pharmacology	Children's Tumor Foundation	The RABL6A-RB1 pathway in MPNST pathogenesis and therapy
Magalhaes-Silverman, Margarida	Internal Medicine	Kadmon Holdings, Inc.	KD025-213 A Phase 2, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of KD025 in Subjects with Chronic Graft Vs Host Disease After at Least 2 Prior Lines of Systemic Therapy (the ROCKstar Study)
Marcinkiewcz, Catherine Anne	Pharmacology	US Department of Health & Human Services, National Institutes of Health	The role of serotonin signaling in the nucleus accumbens in excessive alcohol drinking
Mathews, Katherine Dianne	Pediatrics	Santhera Pharmaceuticals (Switzerland) Ltd	A Phase III Open-Label Extension Study to Assess the Long-Term Safety and Efficacy of Idebenone (Drug) in Patients with Duchenne Muscular Dystrophy (DMD) who completed the SIDEROS study (SIDEROS-E) (Study).
Mathews, Katherine Dianne	Pediatrics	AveXis, Inc.	AveXis Consulting
Mazur, Alexander	Internal Medicine	Attune Medical	Evaluating Active Esophageal Cooling during Cardiac Ablation Procedures
Menda, Yusuf Schultz, Michael K	Radiology	US Department of Health & Human Services, National Institutes of Health	Alpha-Particle Emitter Peptide Receptor Targeted Radionuclide Therapy for Neuroendocrine Tumors
Milhem, Mohammed Mahmoud	Internal Medicine	Merck Sharp & Dohme Company	Adjuvant Therapy with Pembrolizumab versus Placebo in Resected Highrisk Stage II Melanoma: A Randomized, Double-blind Phase 3 Study
Muffly, Scott	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course - Trauma Basic Principles
Nester, Carla Marie	Pediatrics	Novartis Pharmaceuticals Corporation	A randomized, double blinded placebo-controlled dosefinding study of efficacy, pharmacodynamics, safety and tolerability of LNP023 in patients with C3 glomerulopathy
Nizar, Jonathan	Internal Medicine	Iowa Fraternal Order of the Eagles	Sympathetic nerve control of kidney function in obesity-associated hypertension
Paradee, William Jerome	Medicine Administration	University of Alabama at Birmingham	UAB_AAV3164_AAV3297_2019
Pinnaro, Catherina T	Pediatrics	Fraternal Order of Eagles	What causes diabetes in Turner Syndrome
Polgreen, Philip Matthew	Internal Medicine	MTF Biologics	Using Prediction Rules to Estimate Frequency of Deceased Donor Screening Criteria to Increase Tissue Availability
Pugely, Andrew	Orthopaedics and Rehabilitation	Lumbar Spine Research Society	A Multi-Disciplinary Approach to Reduce Chronic Opioid Use Prior to Elective Lumbar Spine Surgery
Rahmouni, Kamal	Pharmacology	US Department of Veterans Affairs	IPA for Deng Fu Guo
Rahmouni, Kamal	Pharmacology	US Department of Veterans Affairs	IPA for Donald Morgan
Ramchandran, Kanchna Phadke, Sneha Deepak	Internal Medicine	Iowa Fraternal Order of the Eagles	Assessing DNA methylation associated with chemotherapy induced cognitive deficits (CICD) in early stage breast cancer in older women
Russell, Michael David	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course - Trauma Basic Principles of Fracture Management
Samaniego, Edgar A	Neurology	University of Cincinnati	StrokeNet: Multi-arm Optimization of Stroke Thrombolysis (MOST) Stroke Trial
Samaniego, Edgar A	Neurology	Rapid Medical Ltd	Tiger Study
Santillan, Mark Kharim	Obstetrics & Gynecology	University of Missouri-Columbia	RSDP Supplement Grant
Scroggins, Sabrina Marie	Obstetrics & Gynecology	American Heart Association	Treatment of Preeclampsia Using Cellular Immunotherapy
Sheffield, Val C	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Novel Genome Editing for the Treatment of Glaucoma
Shy, Michael E	Neurology	Alnylam Pharmaceuticals, Inc.	Alnylam Clinical Trial HELIOS-A:  A Phase 3 Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with hATTR Amyloidosis
Singh, Minati	Internal Medicine	Iowa Fraternal Order of the Eagles	Secret niche of aging brain: Klotho unlocks
Sinn, Patrick Ladd	Pediatrics	Cystic Fibrosis Foundation	Transducing basal cells and ionocytes for CF phenotypic correction
Stapleton, Jack T	Internal Medicine	Bavarian Nordic	POX-MVA-031 Clinical Trial
Tansey, Michael J	Pediatrics	University of South Florida	HYDROXYCHLOROQUINE FOR PREVENTION OF ABNORMAL GLUCOSE TOLERANCE AND DIABETES IN INDIVIDUALS AT-RISK FOR TYPE 1 DIABETES MELLITUS
Taylor, Eric Benjamin	Biochemistry	POXEL	Determination of PXL Compound Mitochondrial Pyruvate Carrier (MPC) IC50 Values
Terry, William Wayne	Pediatrics	Fraternal Order of Eagles	Providing therapeutic supplies to support psycho-social therapies for AYA cancer patients
Usachev, Yuriy M	Pharmacology	US Department of Health & Human Services, National Institutes of Health	The Role of the Complement System in Spinal Mechanisms of Chronic Pain
Vigil Gonzales, Carlos Enrique	Internal Medicine	AbbVie, Inc.	M16-785:  Phase 1b Study of Venetoclax and AMG 176 in Patients with Relapsed/Refractory
Vikram, Ajit	Internal Medicine	American Heart Association	Gut-microbiota regulated vascular miR-204 promotes diabetes-associated endothelial dysfunction
Yan, Ziying	Anatomy & Cell Biology	Cystic Fibrosis Foundation	Gene Editing for Cystic Fibrosis Gene Therapy in Ferret Models
Zakharia, Yousef	Internal Medicine	Calithera BioSciences, Inc.	CX-839-011:  A Phase 1b/2 Open Label, Dose Escalation and Expansion Study of the Glutaminase Inhibitor CB-839 in Combination with the PARP Inhibitor Talazoparib in Patients with Advanced or Metastatic Solid Tumors
Zhang, Jun	Internal Medicine	Big Ten Cancer Research Consortium	BTCRC LUN17-139:  A phase II study or Carboplatin plus Pemetrexed plus Atezolizumab plus Bevacizumab in chemotherapy and immunotherapy-naive patients with stage IV non-squamous non-small cell lung cancer

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MAY 2019

PI	Department	Sponsor	Title
Aksan, Nazan Suheyla	Neurology	US Department of Health & Human Services, National Institutes of Health	Evaluating the disease-modifying potential of a sleep intervention for Alzheimer's Disease outcomes
Anderson, Steven Wayne	Neurology	Iowa State University	Insulin Resistance, Biomarkers of Brain Function, and Intermittent Calorie Restriction
Badovinac, Vladimir	Pathology	US Department of Health & Human Services, National Institutes of Health	Differentiation of pathogen-specific memory CD8 T cell responses
Bender, David Paul	Cancer Center	NRG Oncology Foundation, Inc.	2019 NRG Oncology Member Institution Clinical Trial Fixed Price Subaward Agreement [Expires: 02/28/25]
Bernat, John Andrew	Pediatrics	Idorsia Pharmaceuticals US Inc.	A multi-center, open-label, uncontrolled, single-arm, extension study to determine
Bishop, Gail A	Microbiology	US Department of Veterans Affairs	IPA for Kyp Oxley
Bishop, Gail A	Microbiology	University of North Carolina at Chapel Hill	Function of IL35+B Cells in Pancreatic Cancer
Brenner, Charles Michael	Biochemistry	Cytokinetics, Inc.	Cytokinetics/NAD Service Center Agreement
Carvour, Martha Lydia	Internal Medicine	Mayo Clinic	Enhance arthroplasty research through electronic health records and NLP-enabled informatics
Ellermeier, Craig D	Microbiology	US Department of Health & Human Services, National Institutes of Health	Extra-Cytoplasmic Function Sigma Factor Senses and Responds to Beta-Lactam Stress in Gram-Positive Bacteria
Erickson, Bradley Allan	Urology	Urotronic, Inc.	ROBUST III Clinical Study Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease A Randomized Control Trial
Foster, Kristin Janine	Pediatrics	American Cancer Society	GSCNP Focusing on Emotional & Mental Health in Pediatric & AYA Cancer
Gantz, Bruce Jay	Otolaryngology - Head & Neck Surgery	Cochlear Americas	Impact of Intraoperative Electrocochleography (ECoG) Monitoring on Post-Operative Hearing Preservation
Hajewski, Christina Josephine Femino, John	Orthopaedics and Rehabilitation	Orthopaedic Research & Education Foundation	The Utility of Deltoid Ligament Reconstruction in Syndesmotic Injuries
Harland, Kari Kay	Emergency Medicine	Iowa Department of Public Health	Sexual Violence Prevention Evaluation
Hodgson-Zingman, Denice Marie	Internal Medicine	Abbott	EP Fellowship Grant 2019-20 academic year
Hodgson-Zingman, Denice Marie	Internal Medicine	BIOTRONIK	Biotronik EP Fellowship Grant 2019-20 academic year
Hoffman, Eric Alfred Kruger, Stanley J	Radiology	US Department of Health & Human Services, National Institutes of Health	Hyperpolarized Xe-129 MRI for Functional Lung Phenotyping
Horwitz, Phillip Andrew	Internal Medicine	Abbott	Interventional Cardiology Fellowship Grant 2019-20 academic year
Jabbari, Ali	Dermatology	Insilico Medicine, Inc.	In vivo Preclinical testing of Insilico Medicine Drug for alopecia areata
Kim, Yusung -	Radiation Oncology	Philips Medical Systems, Inc.	Generation of 3D Prescription-Map Plugin in Pinnacle Treatment Planning System (TPS)
Knudson, C Michael	Medicine Administration	Leidos Biomedical Research, Inc. aka SAIC-Frederick	Clinical Proteomics Tumor Analysis Consortium 3.0
Krasowski, Matthew David	Pathology	Abbott Laboratories	Cardiac Troponin Concentrations in Healthly Transgender People
Lenert, Petar	Internal Medicine	Sanofi US Services Inc.	A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis (GCA)
Lentz, Steven	Internal Medicine	Hikari DX, Inc.	Clinical Performance Evaluation of T-TAS 01 PL Chip
Limoli, Dominique	Microbiology	Cystic Fibrosis Foundation	PHASE II_Modulating interspecies interactions in cystic fibrosis respiratory disease
London, Barry Brenner, Charlie Irani, Kaikobad	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Evaluating NAD Supplementation as a Novel Treatment for Arrhythmias
Long, Jeffrey D	Psychiatry	Vanderbilt University	Early detection of Huntington's Disease: Longitudinal analysis of basal ganglia and cortical thickness
Manicassamy, Balaji	Microbiology	US Department of Health & Human Services, National Institutes of Health	Modulation of Influenza Virus Replication and Fitness by Adenosine Deaminases
Mathews, Katherine Dianne	Pediatrics	Muscular Dystrophy Association	Muscular Dystrophy Association Neuromuscular Observational Research (MOVR) Data Hub
Mathews, Katherine Dianne	Pediatrics	AveXis, Inc.	A Managed Access Program (MAP) Cohort Treatment Protocol to provide AVXS-101 to
Mazur, Alexander	Internal Medicine	BIOTRONIK	Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy
Monga, Varun	Internal Medicine	Deciphera Pharmaceuticals, LLC	A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastroinitestinal Stromal Tumors after Treatment with Imatinib (Intrigue)
Nau, Peter Nealey	Surgery	Foundation for Surgical Fellowships	Fellowship in Bariatric Surgery
Panaich, Sidakpal	Internal Medicine	Cleveland Clinic Foundation	WATCH-TAVR Protocol
Petrucci, Alexandra	Neurology	American Epilepsy Society	AES Predoctoral Research Fellowship
Powers, Jennifer Gloeckner	Dermatology	Medical University of South Carolina	INCREASING ACCESS TO CLINICAL MICROBIOME SPECIMENS VIA A LIVING BIOME BANK
Russell, Stephen R	Ophthalmology & Visual Sciences	ProQR Therapeutics B.V.	ORA-ProQR QR-110-002 LCA Extension Study
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	A Phase 2 Study of Inotuzumab Ozogamicin in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
Sharathkumar, Anjali Alatkar	Pediatrics	Hemophilia Alliance Foundation	Patient Navigation for Health Disparity Reduction
Smith, Mark Charles	Radiation Oncology	Elekta, Inc.	Agreement between ELEKTA and UIHC Rad Onc
Snyder, Peter M	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	9th Annual International Conference of Aldosterone and ENaC
Suneja, Manish	Internal Medicine	Alliance for Academic Internal Medicine	AAIM Innovation Grant
Tsalikian, Eva	Pediatrics	Insys Development Company, Inc.	A Multicenter, Open-Label Study to Assess the Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Patients with Prader-Willi Syndrome
Yang, Shujie	Obstetrics & Gynecology	US Department of Health & Human Services, National Institutes of Health	Restoring Progestin Sensitivity in Endometrial Cancer

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APRIL 2019

PI	Department	Sponsor	Title
Allen, Lee-Ann	Internal Medicine	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	(636D93053) -- Studies based on the discovery of neutrophil metabolic Reprogramming as a new mechanism for apoptosis inhibition
Alvarez, Paulino	Internal Medicine	Yale University	TRANSFORM-HF
Benson, Christopher J	Internal Medicine	US Department of Veterans Affairs	36C26319C0088 (636D93054) - Role of ASICs within sensory neurons in health and disease
Cho, Josalyn Leah Olsen	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Airway Dendritic Cells in the Allergic Asthma Phenotype
Faine, Brett Anthony	Emergency Medicine	OLIVE VIEW-UCLA EDUCATION & RESEARCH INSTITUTE	EMERGEncy ID NET Study Group: Management  of Diverticulitis in the Emergency Department
Farooq, Umar	Internal Medicine	Novartis Pharmaceuticals Corporation	Managed Access Program (MAP) to provide access to CTL019 (Novartis), for acute lymphoblastic leukemia (ALL) or large B-cell lymphoma patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for com
Gerke, Alicia	Internal Medicine	Mallinckrodt Pharmaceuticals	Educational Grant for Conference - A. Gerke
Groth, Christopher Lee	Neurology	Emory University	Dystonia Coalition
Gurung, Prajwal	Internal Medicine	Kemin Industries, Inc.	Experimental/Technical Services Agreement with Kemin Industries, Inc.
Harper, Matthew M	Ophthalmology & Visual Sciences	Iowa City Veterans Affairs Research Foundation	ICVARF 18-19 Technician MOU - Harper DOD
Hitchon, Patrick	Neurosurgery	InVivo Therapeutics	Randomized, Controlled, Single-blind Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
Howard, Matthew A	Neurosurgery	California Institute of Technology	Neuronal Substrates of Hemodynamic Signals in the Prefrontal Cortex
Irani, Kaikobad	Internal Medicine	Augusta University	Gut microbiota-regulated metabolism through MicroRNA-204
Johnston, Holly Anne	Radiation Oncology	Varian Medical Systems, Inc.	An automated treatment plan quality assurance tool for gynecological high dose rate brachytherapy based on failure modes and effects analysis
Kaczka, David Walter	Anesthesia	ZOLL Medical Corporation	David Kaczka Paid Consultation to ZOLL Q5 & Q6
Kamholz, John	Neurology	Huntington's Disease Society of America	HDSA Centers of Excellence
Karwal, Mark William	Internal Medicine	Exact Sciences Corporation	Blood Sample Collection to Evaluate Biomarkers for Hepatocellular Carcinoma
Kuehn, Markus H	Ophthalmology & Visual Sciences	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Kuehn VA-PO RA support Validate passive immune transfer
Kuehn, Markus H	Ophthalmology & Visual Sciences	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	VA PO: Kuehn/Cheng T-Cell mediated cytotoxicity in TBI
Langbehn, Douglas Robert	Psychiatry	CHDI  Management, Inc.	Scientific Advisory Committee
Lawrence, Thomas	Surgery	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Hand & Wrist Fracture Management Course
Lenert, Petar	Internal Medicine	Sanofi US Services Inc.	EFC15160 entitled A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with polymyalgia rheumatica (PMR)
Limoli, Dominique Welsh, Michael	Microbiology	Cystic Fibrosis Foundation	Modulating interspecies interactions in cystic fibrosis respiratory disease
Mathews, Katherine Dianne	Pediatrics	PPD Investigator Services, LLC	A Long-term Observational Study Evaluating Eteplirsen in Patients with Duchenne Muscular Dystrophy under Conditions of Routine Clinical Practice
Mazur, Alexander	Internal Medicine	University of Rochester	MARVEN
Mullins, Robert F Tucker, Budd Albert	Ophthalmology & Visual Sciences	US Department of Health & Human Services, National Institutes of Health	Choriocapillaris Protection and Replacement in AMD
Noiseux, Nicolas Olivier	Orthopaedics and Rehabilitation	Smith & Nephew, Inc.	A PROSPECTIVE, MULTI-CENTER CLINICAL STUDY EVALUATING THE LEGIONTM HINGE KNEE SYSTEM (THE LINKS STUDY)
Pena, Tahuanty	Internal Medicine	St. Elizabeth's Medical Center	Impact of Pre-transplant Anti-fibrotic Therapy for IPF upon Lung Transplant Outcomes
Perencevich, Eli N	Internal Medicine	University of Maryland	Epicenters for the Prevention of Healthcare-Associated Infections (HAIs); Cycle II Multicenter Program Studies
Pollard, Janet H	Radiology	Progenics Pharmaceuticals, Inc.	A Phase 3, Multi-Center, Open-Label Study to Assess the Diagnostic Performance and Clinical Impact of 18F-DCFPyL PET/CT Imaging Results in Men with Suspected Recurrence of Prostate Cancer (CONDOR)
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	COG - ALTE07C1
Schweizer, Marin Leigh	Internal Medicine	US Department of Health & Human Services, Agency for Healthcare Research & Quality	Povidone-iodine to Stop Access-related Infections and Transmission of Staphylococcus aureus (PAINTS)
Shy, Michael E	Neurology	Charcot-Marie-Tooth Association	The Inherited Neuropathy Consortium
Sluka, Kathleen A	Physical Therapy	US Department of Health & Human Services, National Institutes of Health	Role of macrophages in activity-induced pain and analgesia
Spies, Maria Malkova, Anna	Biochemistry	US Department of Health & Human Services, National Institutes of Health	The role of human RAD52 protein in genome stability
Swenson, Andrea	Neurology	University of Miami	CReATe- Trial Ready Study
Takacs, Elizabeth Broghammer	Urology	Society of Academic Urologists	Development and Validation of a Novel Urology Residency Evaluation and Feedback System
Tomasson, Michael	Internal Medicine	Hoffmann-La Roche, Inc.	A Phase Ib/II Study Evaluating the Safety and Efficacy of Idasanutlin in Combination with Cytarabine and Daunorubicin in Patients Newly Diagnosed with AML and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission
Vigil Gonzales, Carlos Enrique	Internal Medicine	Rafael Pharmaceuticals, Inc.	AML003:  Phase III Multicenter Open-Label Randomized Trial to Evaluate Efficacy and Safety of CPI-613 in Combination with High Dose Cytarabine and Mitoxantrone (CHAM) Compared to High Dose Cytarabine and Mitoxantrone (HAM) in Older Patients (>/= 60 years)
Wall, Michael	Ophthalmology & Visual Sciences	Dignity Health dba St. Joseph's Hospital & Medical Center	Wall - Open Up Project
Yadav, Ravi Prakash	Molecular Physiology & Biophysics	Knights Templar Eye Foundation, Inc.	Molecular Mechanisms of AIPL1 and its TPR domain in Leber congenital amaurosis
Zakharia, Yousef	Internal Medicine	Astellas Pharma Global Development, Inc.	1951-CL-0101:  A Phase 1 Study of ASP1951 in Subjects with Advanced Solid Tumors
Zhang, Jun	Internal Medicine	Biodesix, Inc.	Investigator Initiated Study - The role of Proteomic as a Predictor for NSCLC Immunotherapy
Zhao, Chen	Pathology	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Synergy of NF-kB and Notch signaling in B cell lymphomatous transformation and B cell plasticity

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MARCH 2019

PI	Department	Sponsor	Title
Alvarez, Paulino	Internal Medicine	Duke University	TRANSFORM-HF
Awelewa, Temitope Modupe	Pediatrics	Duke University	Pediatric Trial Network: PK and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Cadaret, Linda Marie	Internal Medicine	United Therapeutics Corporation	APD811-301
Carter, Calvin Stanley	Pediatrics	American Diabetes Association	Glycemic Lowering Mechanisms of Low-Frequency Electromagnetic Fields in Mouse Models of Type 2 Diabetes
Cornell, Robert A	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Dissecting the transcriptional network governing differentiation of periderm
Dowdle, Spencer	Orthopaedics and Rehabilitation	Globus Medical, Inc.	Education Grant to attend AAOS 2019 Annual Meeting
Fraer, Mony	Internal Medicine	Cara Therapeutics	A MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ORAL CR845 IN CHRONIC KIDNEY DISEASE PATIENTS WITH MODERATE-TO-SEVERE PRURITUS CR845-210301
Gerke, Alicia	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Biomarkers for Severity, Therapy, and Disparity in Sarcoidosis: Discovery to Delivery
Graham, Michael	Radiology	ImaginAb, Inc.	ImaginAb Clinical Trial Agreement
Grose, Charles	Pediatrics	Mayo Clinic	Identification and Characterization of Children with Asthma Associated comorbidities through  computational and immune phenotyping
Gutierrez, Santiago	Neurology	University of Texas Health Science Center at Houston	SEGA - SEdation versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke - a Randomized Comparative Effectiveness Trial.
Hasan, David	Neurosurgery	US Department of Health & Human Services, National Institutes of Health	15-PGDH as a better therapeutic target than aspirin in decreasing risk of intracranial aneurysm rupture in men and women equally
Herwaldt, Loreen A	Internal Medicine	University of Illinois at Chicago	Epicenters for the Prevention of Healthcare-Associated Infections (HAIs); Cycle II Multicenter Program Studies
Huang, Chou-Long	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Klotho and Chronic Kidney Disease
Jackson, Jay Brooks	Medicine Administration	Wells Fargo Wealth Management	Dr. Dennis L. and Mrs. Katheryn M. Boatman Medical Scholarship Fund
Jackson, Jay Brooks	Medicine Administration	Wells Fargo Advisors Financial Network, LLC	Cynthia and Darrel Courtney Colon Cancer Research Fund
Jackson, Jay Brooks	Medicine Administration	Wells Fargo Advisors Financial Network, LLC	Cornea Transplant Research Lab Fund
Jackson, Jay Brooks	Medicine Administration	Seth A Bailey Courage Group, Inc.	Seth A. Bailey Sarcoma Cancer Fund- UIF Special Award
Jethava, Yogesh Shantilal	Internal Medicine	International Myeloma Foundation	Patients with multiple myeloma with t(11;14) translocation identified on plasma cell FISH
Kenny, Helena Catherine	Internal Medicine	MyoKardia, Inc.	OPA1 KO Causes Cardiac Dysfunction, ER Stress and Heart Failure
Larson Ode, Katie Marie Ulring	Pediatrics	Cystic Fibrosis Foundation	EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis
Legge, Kevin L	Pathology	Iowa State University	Universal room temperature stable influenza nanovaccine
Limoli, Dominique	Microbiology	Cystic Fibrosis Foundation	Modulating interspecies interactions in cystic fibrosis respiratory disease
Loftus, Randy Wayne	Anesthesia	Kenall Manufacturing	The Attenuation of Intraoperative S. aureus Transmission and SSIs via Use of Indigo-Clean
McElroy, STEVEN James	Pediatrics	Evolve BioSystems	HAWKEYE
Meier, Jeffery Linn	Internal Medicine	US Department of Veterans Affairs	36C26319C0069 (636D93047) Mechanisms regulating Cytomegalovirus Research for the Iowa City VA Health Care System
Milhem, Mohammed Mahmoud	Internal Medicine	Checkmate Pharmaceuticals	Compassionate use CMP-001 for a single patient with uveal melanoma
Miller, Benjamin James	Orthopaedics and Rehabilitation	Saint Louis University	Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone: A Prospective Randomized Controlled Trial
Monga, Varun	Internal Medicine	NewLink Genetics Corporation	Compassionate use access to indoximod in combination with temozolomide for an adult patient with glioblastoma
Nance, Christopher S	Neurology	Massachusetts General Hospital	NeuroNext Clinical Trial - The TopCSPN Study / Topiramate as a Disease Modifying Therapy for CSPN
Newell, Elizabeth Ann	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Astrocyte-specific IL-1RI signaling effects following traumatic brain injury
Parekh, Kalpaj R	Surgery	US Department of Health & Human Services, National Institutes of Health	Pathogenesis of Airway Stem Cell Abnormalities on Obliterative Bronchiolitis
Philibert, Robert Alan	Psychiatry	University of Connecticut Health Center	Contextual and health behavior effects on epigenetic aging among African Americans
Polyak, Steven	Internal Medicine	AbbVie, Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study to Evaluate the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Ulcerative Colitis
Price, David H	Biochemistry	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Mechanisms regulating cytomegalovirus - IPA Agreement
Ramchandran, Kanchna	Internal Medicine	Fraternal Order of Eagles	Brain-based biomarker tools to assess cognitive deficits associated with early stage breast cancer in older women
Russell, Stephen R	Ophthalmology & Visual Sciences	Spark Therapeutics	SPKRPE-PASS: A Post-Authorization, Multicenter, Multinational, Longitudinal, Observational Safety Registry Study for Patients Treated with Voretigene Neparvovec
Russo, Andrew F	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Perivascular mechanisms of CGRP-induced migraine symptoms
Sainju, Rup K	Neurology	Yale University	New-Onset Refractory Status Epilepticus (NORSE) Study
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	COG - ALTE15N2 - St. Bladrick's Foundation
Shy, Michael E	Neurology	Neurogene, Inc.	March 8 & 9, 2019 Dallas CMT4J Advisory Board Consulting with Neurogene
Simmons, Jonathan S	Anesthesia	Entasis Therapeutics, Inc.	A Multi-center, Retrospective Study of Serious Infections Caused by Acinetobacter baumannii-calcoaceticus Complex
Spies, Maria	Biochemistry	US Department of Defense, Congressionally Directed Medical Research Program	Modulating Cancer Genetics for Immune Regulation and Breast Cancer Therapy
Spies, Maria	Biochemistry	US Department of Health & Human Services, National Institutes of Health	Assembly and Dynamics of Molecular Machines in Genome Maintenance
Staber, Janice Marie Rose	Pediatrics	American Thrombosis and Hemostasis Network	A Natural History Cohort Study of the Safety, Effectiveness, and Practice of Treatment for People with Hemophilia
Stone, Edwin M	Ophthalmology & Visual Sciences	Vanguard	William J. Kimberling, Ph.D., Usher Research Laboratory
Stone, Edwin M	Ophthalmology & Visual Sciences	Vanguard	William J. Kimberling, Ph.D., Usher Research Laboratory
Stone, Edwin M	Ophthalmology & Visual Sciences	Vanguard	William J. Kimberling, Ph.D., Usher Research Laboratory
Strack, Stefan	Pharmacology	Regents of the University of California Davis	Generation and characterization of mouse models of Jordan's Syndrome
Wattiez, Anne-Sophie	Molecular Physiology & Biophysics	US Department of Veterans Affairs	Wattiez VA Pilot - CGRP sensitization in post- traumatic headache
Weiner, George J	Cancer Center	Vanguard	Robert F. and Bertha M. Tribuno Bladder Cancer Research Fund
Weiner, George J	Cancer Center	U.S. Bank	Larry and Darlene Lehmkuhl Fund
Westermann, Robert	Orthopaedics and Rehabilitation	Smith & Nephew, Inc.	Arthroscopic Correction of Femoroacetabular Impingement - A joint Contact  Stress Analysis

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FEBRUARY 2019

PI	Department	Sponsor	Title
Assouline-Dayan, Yehudith Soubra, Mahmoud Rangarajan Murali, Arvind Tran, Huy T T	Internal Medicine	Regeneron Pharmaceuticals, Inc.	A PHASE 3, RANDOMIZED, 3-PART STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF DUPILUMAB IN ADULT AND ADOLESCENT PATIENTS WITH EOSINOPHILIC ESOPHAGITIS
Bender, David Paul	Obstetrics & Gynecology	Big Ten Cancer Research Consortium	Big Ten Consortium-GYN15-013
Cadaret, Linda Marie	Internal Medicine	Bayer AG	VITALITY
Chatterjee, Snehajyoti	Molecular Physiology & Biophysics	Nellie Ball Trust	Investigating the role of the schizophrenia-associated gene Nr4A2 in the regulation of gene expression using a novel tavi-tag approach and single-neuronal nuclear RNA
Day, Molly Owens, Jessell	Orthopaedics and Rehabilitation	Journal of Bone and Joint Surgery	JBJS Orthopedic Resident Journal Club
Farooq, Umar	Internal Medicine	Big Ten Cancer Research Consortium	Phase I Study of Nivolumab in Combination with Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma
Ford, Bradley	Pathology	Accelerate Diagnostics, Inc.	Improving Outcomes and Antibiotic Stewardship for Patients with Bacteremia (IOAS): Accelerate PhenoTestTM BC Kit Registry Study
Gaine, Marie E	Molecular Physiology & Biophysics	Nellie Ball Trust	A longitudinal study of DNA methylation patterns in schizophrenia
Griguer, Corinne E Oliva, Claudia	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Paracrine Signaling in Glioma: Bioenergetics Heterogeneity and Chemoresistance
Gutierrez, Santiago	Neurology	Society of Vascular and Interventional Neurology	Development of a Novel Risk Stratification Score for Patients Presenting with Acute Cerebral Venous Sinus Thrombosis
Hall, Mederic Micah Chimenti, Ruth	Orthopaedics and Rehabilitation	American Medical Society for Sports Medicine Foundation	Efficacy and Safety of Ultrasound Guided Tenotomy
Hansen, Marlan Rex	Otolaryngology - Head & Neck Surgery	Massachusetts Eye and Ear Infirmary	Prospective, randomized, placebo-controlled phase 2 trial of aspirin for vestibular schwannoma
Hasan, David	Neurosurgery	Medtronic, Inc.	2019 University of Iowa Cerebrovascular Research Update Symposium
Herwaldt, Loreen A Schweizer, Marin Leigh	Internal Medicine	PDI Healthcare	Feasibility of Povidone Iodine Decolonization among Orthopedic Trauma Surgery Patients
Law, Ian Harry	Pediatrics	Medtronic, Inc.	ATrial TAchycardia PAcing Therapy in Congenital Heart
Leslie, Kimberly Kay Samuelson, Megan I Gonzalez Bosquet, Jesus Devor, Eric Thiel, Kristina Wyatt Salem, Aliasger Karimjee Au, Kin Fai	Obstetrics & Gynecology	US Department of Health & Human Services, National Institutes of Health	Targeted Therapy for Endometrial Cancer
Link, Brian Krall	Internal Medicine	University of Rochester	A phase III double blind, prospective randomized trial to evaluate the supplemental effect of vitamin D (cholecalciferol) on progression-free survival in patients with low tumor-burden indolent non-Hodgkin lymphoma treated with rituximab therapy (ILyAD -
Manicassamy, Balaji	Microbiology	US Department of Health & Human Services, National Institutes of Health	ENDOTHELIAL CELL TROPISM IN THE PATHOGENESIS AND HOST RESPONSE AGAINST INFLUENZA VIRUSES - RESUBMISSION 01
McGowan, Stephen E	Internal Medicine	US Department of Veterans Affairs	VA IPA for Diann McCoy
McLendon, Jared Milligan	Internal Medicine	American Heart Association	Regulation of Cardiac Signaling by Beta-Taxilin
Milhem, Mohammed Mahmoud	Internal Medicine	Forma Therapeutics, Inc.	A Phase 1b/2 Study of FT-2102 in Patients with Advanced Solid Tumors and Gliomas with an IDH1 Mutation
Milhem, Mohammed Mahmoud	Internal Medicine	Exicure, Inc.	AST-008-102:  A Phase 1b/2 Study of AST-008 Combined with Pembrolizumab in Patients with Advanced Solid Tumors
Milhem, Mohammed Mahmoud	Internal Medicine	Nektar Therapeutics	17-262-01:  A Phase 1/2, Open-label, Multicenter, Dose Escalation and Dose Expansion Study of NKTR-262 in Combination with NKTR-214 and in Combination with NKTR-214 plus Nivolumab in Patients with Locally Advanced or Metastatic Solid Tumor Malignancies (P
Minard, Annabel Yurie	Molecular Physiology & Biophysics	American Diabetes Association	Role of novel Rab10 interactors in Glut4 translocation
Mohr, Nicholas Matthew Ward, Marcia M Chrischilles, Elizabeth A Parker, Edith A	Emergency Medicine	US Department of Health & Human Services, Agency for Healthcare Research & Quality	Evaluating the Role of Telemedicine in Improving Rural Emergency Department Sepsis Care
Nopoulos, Peggy Colleen Conrad, Amy Lynn Magnotta, Vincent Alfonso	Psychiatry	Boston Children's Hospital	Immunologic and Neurodevelopmental Consequences of Neonatal Anemia and Thrombocytopenia and their Treatments
Noureddine, Lama	Internal Medicine	Sanofi-Aventis U.S. Inc.	Multicenter, randomized, double-blind, placebo-controlled two stage study to characterize the efficacy, safety, tolerability and pharmacokinetics of GZ/SAR402671 in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPK
O'Donnell, Michael A	Internal Medicine	Medical Enterprises Europe B.V.	A Multicenter, Single-Arm Study Evaluating the Efficacy of Synergo Radiofrequency-Induced Thermochemotherapy Effect (RITE) with Mitomycin C (Synergo RITE + MMC) in CIS Non-Muscle Invasive Bladder Cancer (NMIBC) Bacillus Calmette-Guerin (BCG)-Unresponsiv
Pearlman, Amy Marcia	Urology	Boston Scientific Corporation	University of Iowa Men's Health Program 2018-2019 Monthly Seminar Line-Up
Polyak, Steven Elliott, David E Cooper, Elizabeth Ann Pederson, Megan Marie	Internal Medicine	University of North Carolina at Chapel Hill	Tofacitinib response in UC (TOUR) - a real world prospective multicenter study
Santillan, Mark Kharim Pierce, Gary L	Obstetrics & Gynecology	University of Pittsburgh	Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	COG - ANBL1531, Jubilant Draximage Inc.
Sato, Takashi Shawn Peter Bansal, Manish	Radiology	Bracco Diagnostics, Inc.	A Prospective Multicenter Observational Study to Evaluate Thyroid Function of Pediatric Subjects from Birth to 3 Years Exposed to Isovue (IOP-120)
Sharathkumar, Anjali Alatkar	Pediatrics	American Thrombosis and Hemostasis Network	A Multicenter Study of Eradication of Hepatitis C Virus (HCV) Infection in People with Hemophilia and Bleeding Disorders (ATHN 6: HCV Eradication Study)
Sharathkumar, Anjali Alatkar	Pediatrics	Pfizer, Inc.	A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF GMI-1070 RIVIPANSEL (GMI-1070) IN THE TREATMENT OF VASO-OCCLUSIVE CRISIS IN HOSPITALIZED SUBJECTS WITH SICKLE CELL DISEASE
Shibli-Rahhal, Amal Ali Choi, James Yuknam	Medicine Administration	Arnold P. Gold Foundation	Arnold P. Gold Foundation Leonard Tow Humanism in Medicine Award
Shy, Michael E	Neurology	Muscular Dystrophy Association	The Inherited Neuropathy Consortium
Song, Long-Sheng	Internal Medicine	US Department of Veterans Affairs	36C26319C0051 (636D93038) Oxidative Stress, PKC Signaling and Heart Failure
Weeks, Kristin	Surgery	Telligen Community Initiative	Scaling the Healthcare Delivery Science and Management Distinction Track
Williams, Aislinn Joanmarie	Psychiatry	Nellie Ball Trust	Investigating cerebellar abnormalities in schizophrenia using patient-derived stem cells

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JANUARY 2019

PI	Department	Sponsor	Title
Bathla, Girish	Radiology	Siemens Medical Solutions USA, Inc.	Neuro Software Evaluation CT
Berg, Daniel J	Cancer Center	NSABP Foundation, Inc.	NSABP Protocol C-13.1
Bernat, John Andrew	Pediatrics	Protalix Biotherapeutics	Open Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegunigalsidase Alfa (PRX-102) 2 mg/kg Administered by Intravenous Infusion Every 4 Weeks in Patients with Fabry Disease
Boudreau, Ryan Lee	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Regulation and role of the cardiac sodium channel Nav1.5 in heart failure
Dai, Dao-Fu	Pathology	US Department of Health & Human Services, National Institutes of Health	The role of energy sensor signaling in mitochondrial cardiomyopathy
Day, Molly	Orthopaedics and Rehabilitation	Mid-America Orthopaedic Association	Mid-America Orthopaedic Association Education Grant
Dhanesha, Nirav Anilkumar	Internal Medicine	American Society of Hematology	Novel mechanisms for arterial and venous thrombosis
Engelhardt, John F	Anatomy & Cell Biology	Talee Bio, Inc.	SOW #1
Erickson, Bradley Allan	Urology	Boston Scientific Corporation	2019-2020 Urology Fellowship
Exil, Vernat	Pediatrics	American Heart Association	Gestational exposure to eCIGS and susceptibility to allergic asthma and bronchopulmonary dysplasis
Falls, Kelly Christine	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Targeting lung and breast cancer cell oxidative metabolism with D-penicillamine and disulfiram
Farooq, Umar	Internal Medicine	Big Ten Cancer Research Consortium	Phase I/II Study of Ixazomib and Romidepsin in Relapsed/ Refractory Peripheral T-cell Lymphoma (PTCL)
Fingert, John Harrison Anderson, Michael Gary	Ophthalmology & Visual Sciences	US Department of Health & Human Services, National Institutes of Health	CRISPR/Cas9 approaches to model exfoliation syndrome
Fraer, Mony	Internal Medicine	Arbor Research Collaborative for Health	CKDOPPS
Fredericks, Douglas Christian	Orthopaedics and Rehabilitation	Prosidyan, Inc.	Statement of Work No. One
Gantz, Bruce Jay	Otolaryngology - Head & Neck Surgery	Cochlear Americas	Nucleus Hybrid L24 Implant System New Enrollment Post Approval Study
Garje, Rohan	Internal Medicine	Endocyte, Inc.	PSMA-617-01:  An International, Prospective, Open-Label, Multicenter, Randomized Phase 3 Study of 177Lu-PSMA-617 in the Treatment of Patients with Progressive PSMA-Positive Metastatic Castration-Resistant Prostate Cancer
Graves, Stephen Andrew	Radiology	MIM Software Inc.	MIM Beta Software Evaluation NDA
Griguer, Corinne E	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Cytochrome C Oxidase: Biomarker In Newly Diagnosed Glioblastoma Multiforme
Gutmann, Laurie	Neurology	argenx BVBA	CTA- Inc Research, LLC, Protocol # ARGX-113-1704
Hadlandsmyth, Katherine E	Anesthesia	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain
Hendrickson, Nathan R	Orthopaedics and Rehabilitation	Mid-America Orthopaedic Association	Mid-America Orthopaedic Association Education Grant
Hodgson-Zingman, Denice Marie	Internal Medicine	Cardiac Pacemakers, Inc. dba Boston Scientific CRM	PREcision Event Monitoring of PatienTs with Heart Failure using HeartLogic
Hodgson-Zingman, Denice Marie	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	A New Pacing Approach for Cardioprotection and Repair in Heart Failure
Howe, James Robinson	Surgery	Children's Hospital of Philadelphia	CHOP Collaborative Research Agreement
Imai, Yumi	Internal Medicine	American Diabetes Association	Regulation of insulin secretion by lipid droplet proteins!
Irani, Kaikobad	Internal Medicine	US Department of Veterans Affairs	36C26319C0052 (636D93040) SIRTUIN1-mediated inhibition of P66shc lysine acetylation as a novel treatment for diabetic vasculopathy
Kaczka, David Walter	Anesthesia	ZOLL Medical Corporation	David Kaczka Paid Consultation to ZOLL Q4
Kardon, Randy Herbert	Ophthalmology & Visual Sciences	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	VA-PO: Kardon/Gramlich The impact of electrical activity and stem cell derived factors
McGowan, Stephen E	Internal Medicine	US Department of Veterans Affairs	36C26319C0058 (636D93036) Contract for Diann McCoy
Mohr, Nicholas Matthew	Emergency Medicine	Iowa Department of Public Health	The Iowa Department of Public Health Trauma System Verification Physician Team member Agreement
Ochoa Nunez, Luis Alberto	Pediatrics	AltaThera Pharmaceuticals LLC	(Retrospective) Intravenous Sotalol in Pediatric and Congenital Patients: A Multi-center Registry
Pezzulo, Alejandro Antonio	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Heat-shock protein 90 modulates goblet cell metaplasia in human airway epithelia
Reisinger, Heather Schacht	Internal Medicine	US Department of Veterans Affairs	36C26319C0045 (636D93024) Building an Optimal health and hygiene Bundle:  A mixed-Methods Approach (CRE 12-289)
Santillan, Mark Kharim	Obstetrics & Gynecology	US Department of Health & Human Services, National Institutes of Health	Vasopressin and Preeclampsia: Early Mechanisms for Prevention
Schweizer, Marin Leigh	Internal Medicine	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Chronic Antibiotic Suppression after Prosthetic Joint Infection: A Target for De-Implementation
Sharafuddin, Melhem J	Surgery	W. L. Gore & Associates	Gore AAA 13-03 Study
Solimeo, Samantha Leigh	Internal Medicine	US Department of Veterans Affairs	36C26319C0031(636D93033) Identifying Barriers to Implementation and Spread of Specialty Care Telehealth PACT Serving Rural Veterans
Spies, Maria	Biochemistry	Iowa State University	Analyzing paleo-enzymology data of homologous genetic recombination
Stapleton, Jack T	Internal Medicine	Janssen Vaccines & Prevention B.V.	A Randomized, Double-blind, Placebo-controlled First-in-Human, Phase 1/2a Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Monovalent HPV16 and HPV18 Ad26-vectored Vaccine Components and an MVA-vectored HVP 16/18 Vaccine Component in Oth
Swenson, Andrea	Neurology	Worldwide Clinical Trials, Inc.	A Phase III, Randomised, Placebo-Controlled Trial of Arimoclomol in Amyotrophic Lateral Sclerosis
Tansey, Michael J	Pediatrics	Amgen, Inc.	Double-blind, Randomized, Multicenter, Placebo-Controlled, Parallel Group Study to Characterize the Efficacy, Safety, and Tolerability of 24 Weeks of Evolocumab for Low Density Lipoprotein-Cholesterol (LDL-C) Reduction, as Add-On to Diet and Lipid-Loweri
Taylor, Eric Benjamin	Biochemistry	Cirius Therapeutics, Inc.	Cirius Therapeutics
Tsalikian, Eva	Pediatrics	Ascendis Pharma A/S	enliGHten: A Multicenter, Phase 3, Long-term, Open-label Trial Investigating Safety and Efficacy of TransCon hGH Administered Once-Weekly in Children with Growth Hormone Deficiency (GHD) Who Have Completed a Prior TransCon hGH Clinical Trial
Tsalikian, Eva	Pediatrics	EMMES Corporation	A double-blind, randomised, placebo-controlled, parallel group
Tsalikian, Eva	Pediatrics	Insys Development Company, Inc.	A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Efficacy, Safety, and Tolerability of Cannabidiol Oral Solution for the  Treatment of Patients with Prader-Willi Syndrome
Tucker, Budd Albert Mullins, Robert F	Ophthalmology & Visual Sciences	US Department of Health & Human Services, National Institutes of Health	Molecular Basis of Complement Defense in Choroidal Endothelial Cells
Weiner, George J	Cancer Center	American Cancer Society	American Cancer Society - IRG
Wilson, Mary E	Internal Medicine	US Department of Veterans Affairs	36C26319C0050 (636D93037) The Role of Exosomes in the Pathogenesis of Leishmaniasis
Wolf, Brian Robert	Orthopaedics and Rehabilitation	University of Kentucky	MOON Shoulder Instability 6 year follow up
Zakharia, Yousef	Internal Medicine	Pfizer, Inc.	A Therapeutic Trial for Safety and Preliminary Efficacy of the Combination of Axitinib and Selenium in the Chemical Composition of Selenomethionine (SLM) for adult patients with advanced metastatic clear cell renal cell carcinoma (CCRCC)
Zakharia, Yousef	Internal Medicine	Eisai, Inc.	(IIS) Proof of concept for lenvatinib and everolimus prior to cytoreductive nephrectomy in eligible patients with locally advanced an metastatic renal cell carcinoma (RCC)
Zhao, Chen	Pathology	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Synergy of NF-kB and Notch signaling in B cell lymphomatous transformation and B cell plasticity
Zhu, Eliot	Anatomy & Cell Biology	Melanoma Research Foundation	Identification of Src family kinases that drive resistance to mutant BRAF inhibition

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DECEMBER 2018

PI	Department	Sponsor	Title
Abel, Edwin G	Molecular Physiology & Biophysics	University of Pennsylvania	Neural mechanisms underlying sleep disturbances in autism spectrum disorder
Abel, Edwin G	Molecular Physiology & Biophysics	Yale University	Translating Drug Discovery in Zebrafish and Mouse Models of ASD Risk Genes
Ahrens, Richard C	Pediatrics	Proteostasis Therapeutics, Inc.	A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PTI-808 in Healthy Adult Subjects and in Adults with Cystic Fibrosis
Bernat, John Andrew	Pediatrics	Protalix Biotherapeutics	Extension: A Randomized, Double blind, Active Control Study of the Safety and Efficacy of PRX-102 compared to Agalsidase Beta on Renal Function in Patients with Fabry Disease Previously Treated With Agalsidase Beta
Cadaret, Linda Marie	Internal Medicine	Lung Biotechnology Inc.	BEAT Extension
Chauhan, Anil	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Novel therpeautic interventions to treat ischemic stroke
Chitneni, Shobha	Internal Medicine	Alliance Foundation Trials, LLC	AFT-39:  Electronic patient reporting of symptoms during outpatient cancer treatment: A U.S. national randomized controlled trial (the PRO-TECT trial)
Choi, Kent Choung	Surgery	Atox Bio Ltd.	Phase 2 randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of Reltecimod as compared to placebo in addition to standard of care in patients with sepsis-associated acute kidney injury (SA-AKI)
Ciliberto, Michael Anthony	Pediatrics	Marinus Pharmaceuticals, Inc.	: A Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone Treatment in Children and Young Adults with Cyclin-dependent Kinase-like 5 (CDKL5) Deficiency Disorder (CDD) Followed by Long-term Open-label Treatment
Davis, James Muse	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Fungal and Host Factors in Initiation of Cryptococcal Persistence
Derdeyn, Colin P	Radiology	University of Cincinnati	NeuroEndovascular Advisory Committee Chair, Imaging Core Trial Liaison
Diekema, Daniel James	Internal Medicine	Johns Hopkins University	Clostridium difficile Over Testing (C-DOT) Improvement initiative; a Multi-Prevention Epicenter Collaborative Project
Drack, Arlene V	Ophthalmology & Visual Sciences	Foundation Fighting Blindness	BBS10 project-Canadian FFB
Harty, John	Microbiology	US Department of Health & Human Services, National Institutes of Health	T resident memory in the lung
Hoffman, Eric Alfred	Radiology	OscillaVent, Inc.	Device for Multi-Frequency Oscillatory Ventilation in Adult Patients with the Acute Respiratory Distress Syndrome
Karam, Matthew David Anderson, Donald D	Orthopaedics and Rehabilitation	Orthopaedic Trauma Association	Introducing Wire Navigation Simulation to the OTA Resident Fracture Courses
Kenny, Helena Catherine	Internal Medicine	American Heart Association	Inducible Deletion of OPA1 Causes Mitochondrial Fragmentation, ER stress and Cardiac Dysfunction
Kumar, Rahul	Internal Medicine	American Heart Association	Memory deficits and sensorimotor impairment in hyperhomocysteinemic mice before and after stroke
Laux, Douglas Earl	Internal Medicine	Immunicum AB	A randomized, open-label, multicenter, phase 1b/2 trial evaluating the safety and efficacy of intratumorally-administered ilixadencel in combination with checkpoint inhibitor (CPI) in advanced cancer subjects who are candidates for CPI therapy
Long, Jeffrey D	Psychiatry	Massachusetts General Hospital	Disease-Modifying Genes in Huntington's Disease
Luo, Yi	Urology	NanoMedTrix LLC	Ultrasound-based diagnostic and monitoring of bladder cancer treatment with drug released from nanoparticles
Mathews, Katherine Dianne	Pediatrics	Sarepta Therapeutics	Sarepta Global Advisory Board Meeting
Mathews, Katherine Dianne	Pediatrics	Catabasis Pharmaceuticals	A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, GLOBAL PHASE 3 STUDY OF EDASALONEXENT IN PEDIATRIC PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY
Michaelson, Jacob J	Psychiatry	Simons Foundation Autism Research Initiative	The neuroscience and genetic basis of twice exceptionality: a pilot study
Milhem, Mohammed Mahmoud	Internal Medicine	Merck Sharp & Dohme Company	A Multicenter, Open label, Phase III Extension Trial to Study the Long-term Safety and Efficacy in Participants with Advanced Tumors Who are Currently on Treatment or in Follow-up in a Pembrolizumab Trial.
Nayak, Manasa Kumar	Internal Medicine	American Heart Association	Role of aerobic glycolysis in platelet function and thrombosis
Perlman, Seth Javier	Pediatrics	CSL Behring L.L.C.	Randomized Study of Single vs. Multiple Privigen Dose Regimens
Polgreen, Philip Matthew	Internal Medicine	University of Utah	Analysis of Contract Networks in a National sample of Long Term Care facilities
Sanchez, Antonio Jaime	Internal Medicine	Enanta Pharmaceuticals, Inc.	A Phase 2 Dose Ranging, Randomized, Double Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects with Primary Biliary Cholangitis (PBC) With or Without an Inadequate Response to UDCA
Segal, Rachel Shana	Pediatrics	American Academy of Pediatrics	Healthy Hawkeye Smiles
Singh, Namrata	Internal Medicine	Rheumatology Research Foundation	Impact of early therapy with tumor necrosis factor inhibitors on lymphoma risk in patients with rheumatoid arthritis
Smith, Richard J	Otolaryngology - Head & Neck Surgery	ArTara Therapeutics	Immunotherapy for the Treatment of Lymphatic Malformations
Starner, Timothy Duane Hornick, Douglas B	Pediatrics	Cystic Fibrosis Foundation Therapeutics, Inc.	Therapeutics Development Center Renewal Progress Report
Uc, Ergun Y	Neurology	Parkinson's Foundation	Parkinson's Foundation Center of Excellence
Wattiez, Anne-Sophie	Molecular Physiology & Biophysics	American Headache Society	Photosensitivity, tactile hypersensitivity and pain-related facial features as objective biomarkers of chronic PTH
Weiss, David S	Microbiology	US National Science Foundation	REU Site: Microbiology at The University of Iowa
Zakharia, Yousef	Internal Medicine	Big Ten Cancer Research Consortium	Phase 1b Clinical Trial of Eribulin Mesylate and the PD-L1 Monoclonal Antibody, Avelumab, in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients
Zhang, Zeyuan	Anatomy & Cell Biology	American Heart Association	Establish the role of impairment of the adaptive unfolded protein response in defective hepatic autophagy in obesity

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NOVEMBER 2018

PI	Department	Sponsor	Title
Adams, Christopher Maxin	Internal Medicine	Emmyon, Inc.	Development of Novel Small Molecule Therapies for Skeletal Muscle Atrophy
Adams, Denise Allene Martinez	Medicine Administration	Robert Wood Johnson Foundation	Summer Health Professions Education Program
Ahmad, Ferhaan	Internal Medicine	MyoKardia, Inc.	MAVERICK-HF
Ashwath, Ravi Chandra	Pediatrics	Actelion Clinical Research, Inc.	A prospective, multicenter, open-label, single-arm, Phase 2 study to investigate the safety, tolerability and pharmacokinetics of selexipag in children with pulmonary arterial hypertension
Bailey, Jane Allison	Ophthalmology & Visual Sciences	Icahn School of Medicine at Mount Sinai	Surgical Idiopathic Intracranial Hypertension Treatment Trial (SIGHT)
Bobb, Morgan R	Emergency Medicine	Emergency Medicine Foundation	Undertriage of Rural Pediatric Trauma Patients: A Statewide Administrative Data Pilot Project
Comellas, Alejandro	Internal Medicine	Gala Therapeutics Inc.	A Safety Evaluation of the Gala Airway Treatment
Deng, Guorui	Pharmacology	American Heart Association	Mechanisms of angiotensin AT1A signal transduction in AgRP neurons for metabolic rate control
Fredericks, Douglas Christian	Orthopaedics and Rehabilitation	Radius Health, Inc.	Assessment of Abaloparatide in a Rat Posterolateral Fusion Model
Gaddam, Ravinder Reddy	Internal Medicine	American Heart Association	Gut-microbiota regulated vascular microRNA-204 promotes endothelial dysfunction in diabetes.
Gerke, Alicia	Internal Medicine	Mallinckrodt ARD, Inc.	A Phase 4, Multicenter, Randomized, Double Blind, Placebo Controlled Pilot Study to Assess the Efficacy and Safety of H.P. Acthar Gel in Subjects With Pulmonary Sarcoidosis
Hasan, David	Neurosurgery	Medicure, Inc.	iSPASM Induced Suppression of Platelets Activity in Aneurysmal SAH Management
Howard, Matthew A	Neurosurgery	California Institute of Technology	Casual mapping of emotion networks with concurrent electrical stimulation and fMRI
Kaczka, David Walter	Anesthesia	ZOLL Medical Corporation	David Kaczka Paid Consultation to ZOLL Q3
Knudson, C Michael	Medicine Administration	Leidos, Inc.	TPC NCI PDX
Milhem, Mohammed Mahmoud	Internal Medicine	Seattle Genetics, Inc.	SGN S40-001: A phase 1, open-label, dose-escalation study of SEA-CD40 in adult patients with advanced malignancies.
Parker, Krystal Lynn	Psychiatry	US Department of Health & Human Services, National Institutes of Health	Cerebellar circuits, timing, and cognition
Perlman, Stanley	Microbiology	New York Blood Center	Structure-based design of coronavirus subunit vaccines
Schlievert, Patrick Michael	Microbiology	Procter & Gamble Company	TSST-1 Toxin Testing
Sears, Nathaniel Charles	Ophthalmology & Visual Sciences	American Glaucoma Society	AGS Clinician Scientist-Making and characterizing a hybrid genetic/experimental mouse model of glaucoma
Singh, Uday	Pharmacology	American Heart Association	The role of PVN MC4R circuits in obesity-associated hypertension
Smith, Richard J	Otolaryngology - Head & Neck Surgery	AdMIRx, Inc.	The Evaluation of Complement Inhibition using an Anti-complement Therapeutic
Smith, Richard J Nester, Carla Marie	Otolaryngology - Head & Neck Surgery	Novartis Corporation	C3 GLOMERULOPATHY - A LONGITUDINAL AND DISCOVERY STUDY
Tanas, Munir-Zakary Raja	Pathology	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Upstream requlation of TAZ and YAP in sacromas
Van Der Plas, Ellen Aaltje Adriana	Psychiatry	American Cancer Society, Iowa Affiliate	CHILDHOOD CANCER AND PSYCHOSOCIAL DEFICITS: PROSPECTIVE
Wood, Kelly Elizabeth	Pediatrics	BiliCam, LLC.	BiliCam (Study Device)
Zakharia, Yousef	Internal Medicine	Big Ten Cancer Research Consortium	Single Arm Phase Ib/II Study of Durvalumab and Quadecitabine in Advanced Kidney Cancer
Zhan, Fenghuang	Internal Medicine	Myeloma Crowd	Targeting CD24 to eliminate myeloma stem cells

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OCTOBER 2018

PI	Department	Sponsor	Title
Abel, Edwin G	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Molecular, Cellular and Circuit Effects of Sleep Deprivation on Hippocampal Function
Abreu, Alison Cornelia	Psychiatry	US Department of Health & Human Services, Substance Abuse & Mental Health Services Administration	Collaborative Medication Assisted Treatment in Iowa (Co-MAT-IA)
Abreu, Alison Cornelia	Psychiatry	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Collaborative Medication Assisted Treatment for Veterans (VET-MAT-IA)
Ahmad, Ferhaan	Internal Medicine	MyoKardia, Inc.	EXPLORER-HCM
Anderson, Carryn M	Radiation Oncology	Galera Therapeutics, Inc.	A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Superoxide Dismutase Mimetic GC4419 to Reduce Severe Oral Mucositis (SOM)....
Bender, David Paul	Obstetrics & Gynecology	Clovis Oncology, Inc.	GOG-3020/ CO-338-087/ Athena
Bernat, John Andrew	Pediatrics	Idorsia Ltd	A multicenter, double-blind, randomized, placebo controlled, parallel-group study to determine the efficacy and safety of lucerastat oral monotherapy in adult subjects with Fabry disease
Bollier, Matthew John	Orthopaedics and Rehabilitation	CONMED Corporation	Univ. of Iowa Sports Medicine Fellowship
Chan, Carlos Hou Fai	Cancer Center	Memorial Sloan-Kettering Cancer Center	A Phase III Multicenter, Open Label Randomized Controlled Trial of Cefoxitin versus Piperacillin-Tazobactam as Surgical Antibiotic Prophylaxis in Patients Undergoing Pancreatoduodenectomy
Choi, Kent Choung	Surgery	Polyphor Ltd	Clinical study No POL7080-010 with murepavadin
Comellas, Alejandro	Internal Medicine	University of North Carolina at Chapel Hill	Genomics and Informatics Center for the SubPopulations and InteRmediate Outcomes Measures in COPD Study (SPIROMICS)
Coryell, William H	Psychiatry	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Collaborative Medication Assisted Treatment for Veterans (VET-MAT-IA)
Dejong, Stacey	Physical Therapy	Medical University of South Carolina	Effects of operant up-conditioning of motor evoked potentials on corticospinal and spinal reflex excitability in people with wrist flexor hypertonia after stroke
Dunn-Johnson, Camille C	Otolaryngology - Head & Neck Surgery	Advanced Bionics Corporation	Audiologic Outcomes and Assessment of Real-World Benefits for Cochlear Implantation Using the Advanced Bionics HiFocus SlimJ Electrode
Elliott, David E	Internal Medicine	ImmusanT, Inc.	A PHASE 2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY IN HLA-DQ2.5+ ADULTS WITH CELIAC DISEASE TO ASSESS THE EFFECT OF NEXVAX2 ON SYMPTOMS AFTER MASKED GLUTEN FOOD CHALLENGE
Ferguson, Nkanyezi Ngwenyama	Dermatology	American Academy of Dermatology	Educational outreach initiative in South Africa concerning the pervasive risk of harmful chemicals contained in over-the-counter topical and cosmetic products
Furqan, Muhammad	Internal Medicine	Checkmate Pharmaceuticals	A MULTICENTER, TWO-PART, PHASE 1b CLINICAL STUDY OF CMP-001 IN COMBINATION WITH ATEZOLIZUMAB WITH AND WITHOUT RADIATION THERAPY IN SUBJECTS WITH ADVANCED NON SMALL CELL LUNG CANCER (NSCLC)
Hadlandsmyth, Katherine E	Anesthesia	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	VA IPA Katherine Hadlandsmyth-Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain
Hadlandsmyth, Katherine E	Anesthesia	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	VA IPA Lori Stout-Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain
Hamzeh, Nabeel Y	Internal Medicine	Pulmonary Fibrosis Foundation	CD4 T-cell immunephenotype in hypersenstivity pneumonitis.
Hansen, Marlan Rex	Otolaryngology - Head & Neck Surgery	Decibel Therapeutics, Inc.	VGLUT3 Study
Harshman, Lyndsay Anne	Pediatrics	Children's Hospital of Philadelphia	Chronic Kidney Disease in Children Prospective Cohort Study
Howard, Matthew A	Neurosurgery	Icahn School of Medicine at Mount Sinai	Surgical IIH Treatment Trial
Magalhaes-Silverman, Margarida	Internal Medicine	Incyte Corporation	A phase III randomized open-label multi-center study of Ruxolitinib vs. best available therapy in patients with corticosteroid-refractory chronic graft vs host disease after allogeneic stem cell transplantation (REACH 3).
Mathews, Katherine Dianne	Pediatrics	rareLife solutions inc.	Cure Duchenne Steroid Education Initiative
Mathews, Katherine Dianne	Pediatrics	Institute For Advanced Clinical Trials For Children, Inc.	2018 InstituteforAdvancedClinicalTrialsforChildren Site Agmt I-ACT[Expires:9-27-2023]
McCray, Paul B	Pediatrics	Talee Bio, Inc.	TL-102 Phase I Sponsored Research
Miller, Delwyn Deon	Psychiatry	University of California, San Diego	T2 PROTECT AD
O'Donnell, Michael A	Cancer Center	Hoosier Cancer Research Network, Inc.	Phase I/II Study of Modern Immunotherapy in BCG-Relapsing Urothelial Carcinoma of the Bladder (ADAPT) HCRN GU16-
O'Dorisio, M Sue	Pediatrics	Fraternal Order of Eagles	Molecularly Targeted Therapy for Pediatric Brain Tumors
Peterson, Ashley Lea	Pediatrics	Cystic Fibrosis Foundation	Using AAV as a delivery vehicle for gene addition or gene editing in pigs
Ryan-Lee, Kathleen Marie	Surgery	Community Foundation of Johnson County, Iowa	Fall Prevention Awareness, Health and Resource Fair
Sanchez, Antonio Jaime	Internal Medicine	Salix Pharmaceuticals, Inc.	A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE)
Spies, Maria Washington, M Todd	Biochemistry	University of Kansas Medical Center	APE1 Cleavage Mechanisms during DNA Repair
Swenson, Andrea	Neurology	Amylyx Pharmaceuticals, Inc.	Centaur-  Open label extension of Phase II Clinical Trial to Evaluate Safety, Tolerability, and Biomarker Engagement of AMX0035 in Patients with ALS
Teran, Frida	Neurology	US Department of Health & Human Services, National Institutes of Health	A novel dietary therapy for epilepsy: potential mechanisms of action
Thomas, Alexandra Hammond, Donna	Anesthesia	US Department of Health & Human Services, National Institutes of Health	Phase II Trial of Nicotinamide Riboside for Relief of Taxane-Induced Sensory Neuropathy
Tsalikian, Eva	Pediatrics	Amgen, Inc.	Prospective, Multicenter, Single-arm Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Denosumab in Children With Osteogenesis Imperfecta
Uc, Aliye	Pediatrics	US Department of Health & Human Services, National Institutes of Health	A Randomized Trial of a Web-based Non-Pharmacological Pain Intervention for Pediatric Chronic Pancreatitis
Uthoff, Johanna Mariah	Radiology	American Lung Association	Lung Cancer Risk Assessment Using Quantitative Imaging Features From Nodule, Lung Parenchyma, and Whole Lung
Wibbenmeyer, Lucy A	Surgery	MediWound Ltd.	A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid compared to Standard of Care (SOC) treatment-MW2012-01-01 (the Study Drug)
Wilken, Jason Mitchell	Physical Therapy	US Department of Defense, Congressionally Directed Medical Research Program	OP170060 Comparative Effect of Commercially Available Custom Dynamic Orthoses (CDOs)
Wilken, Jason Mitchell	Physical Therapy	University of Delaware	Objective Clinical Prescription of Passive-Dynamic Ankle-Foot Orthoses to Optimize Patient Outcomes
Wolf, Brian Robert	Orthopaedics and Rehabilitation	Vanderbilt University	Operative versus Non-operative Treatment for Atraumatic Rotator Cuff Tears:  A Multicenter Randomized Controlled Pragmatic Trial
Zakharia, Yousef	Internal Medicine	University of Texas Southwestern Medical Center	Multi-site immune biomarker study - Iowa

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SEPTEMBER 2018

PI	Department	Sponsor	Title
Adams, Christopher Maxin	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Novel signaling pathways underlying skeletal muscle atrophy
Ahrens, Richard C	Pediatrics	Proteostasis Therapeutics, Inc.	A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Pharmacokinetics of PTI-428 in Subjects with Cystic Fibrosis
Aldridge, Georgina	Neurology	US Department of Health & Human Services, National Institutes of Health	Cortical Mechanisms in Lewy Body Dementia
Anderson, Donald D	Orthopaedics and Rehabilitation	University of Kansas Medical Center Research Institute, Inc.	Accelerating Osteoarthritis Clinical Trials Through Low-Dose Standing CT Imaging
Bassuk, Alexander G Mahajan, Vinit Bharati	Pediatrics	Stanford University	Evaluating GWAS AMD Candidate Loci by Gene Editing in Human iPS Cells
Buckwalter, Joseph Addison	Orthopaedics and Rehabilitation	US Department of Defense, Congressionally Directed Medical Research Program	PR172087 - Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA
Cadaret, Linda Marie	Internal Medicine	Actelion Clinical Research, Inc.	RETRO
Coleman, Mitchell Carl	Radiation Research Laboratory	US Department of Health & Human Services, National Institutes of Health	Do Changes in Thiol Metabolism Mediate Osteoarthritis Progression?
Cornell, Robert A	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Dissecting the transcriptional network governing differentiation of periderm
Cullen, Joseph John Spitz, Douglas Robert	Surgery	US Department of Health & Human Services, National Institutes of Health	Exploiting Redox Metabolism Using Pharmacological Ascorbate for Cancer Therapy
Dick, David Wayne	Radiology	US Department of Energy	Support for Students, Postdoctoral Fellows and Trainees to Attend the 17th International Workshop on Targetry and Target Chemistry
Doerschug, Kevin Clarke	Internal Medicine	ALung Technologies, Inc.	A Prospective, Multi-Center, Randomized, Controlled, Pivotal Trial to Validate the Safety and Efficacy of the Hemolung
Gaine, Marie E	Molecular Physiology & Biophysics	Brain & Behavior Research Foundation	Investigating DNA methylation changes in schizophrenia subjects compared to first-degree relatives
Gerke, Alicia	Internal Medicine	Boehringer Ingelheim Pharmaceuticals, Inc.	An open-label extension trial to assess the long term safety of nintedanib in patients with 'Systemic Sclerosis associated Interstitial Lung Disease' (SSc-ILD)
Greiner, Alexander Michael	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Assessing the Impact of MSX1 in Cardiac Fibrosis and Sudden Cardiac Death
Gutmann, Laurie	Neurology	Massachusetts General Hospital	Clinical Coordinating Center Network of Excellence in Neuroscience Clinical Trial
Hammond, Donna L	Anesthesia	US Department of Veterans Affairs	VA Vision Contract: Nicotinamide Riboside for the Relief of Painful Dry Eye Syndrome
Hodgson-Zingman, Denice Marie	Internal Medicine	Biosense Webster, Inc.	Biosense Webster EP Fellowship Grant 2018-19 academic year
Hodgson-Zingman, Denice Marie	Internal Medicine	BIOTRONIK	Biotronik EP Fellowship Grant 2018-19 academic year
Idiga, Sharon	Pharmacology	US Department of Health & Human Services, National Institutes of Health	Novel Endocrine Circuit Regulating Sugar Satiety
Kardon, Randy Herbert	Ophthalmology & Visual Sciences	US Department of Veterans Affairs	36C26318P3479 (636D83065) Provide Services with Org Data Answering Inquiries
Lentz, Steven	Internal Medicine	Novo Nordisk, Inc.	Pathfinder 8
Loftus, Randy Wayne	Anesthesia	Anesthesia Patient Safety Foundation	Reducing Perioperative S. aureus Transmission via use of an Evidence-Based, Multimodal Program Continually Optimized by Innovative Surveillance (OR PathTrac)
Marcinkiewcz, Catherine Anne	Pharmacology	Brain & Behavior Research Foundation	Deconstructing prefrontal connectivity with the dorsal raphe in social behavior
Mathews, Katherine Dianne	Pediatrics	Biogen MA, Inc.	Biogen Advisory Board: National Discussion Around Emerging Therapies Advisory Board (East)
Mathews, Katherine Dianne	Pediatrics	AMO Pharma	A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Tideglusib Versus Placebo for the Treatment of Children and Adolescents with Congenital Myotonic Dystrophy
McCray, Paul B	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Milhem, Mohammed Mahmoud	Internal Medicine	INC Research, LLC	A Phase 1b, Multicenter, Open-Label Study of DSP-7888 Dosing Emulsion in Combination with Immune Checkpoint Inhibitors Nivolumab or Atezolizumab in Adult Subjects with Advanced Solid Tumors
Nester, Carla Marie	Pediatrics	Retrophin, Inc.	A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PARALLEL, ACTIVECONTROL STUDY OF THE EFFECTS OF SPARSENTAN, A DUAL ENDOTHELIN RECEPTOR AND ANGIOTENSIN RECEPTOR BLOCKER, ON RENAL OUTCOMES IN PATIENTS WITH PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS)
Nopoulos, Peggy Colleen	Psychiatry	US Department of Health & Human Services, National Institutes of Health	Transfusion of Prematurity Early School Age Follow-up (TOP 5) CCC
Nourski, Kirill Vadimovich	Neurosurgery	University of Wisconsin-Madison	Mechanisms of anesthetic-induced unconsciousness
Perencevich, Eli N	Internal Medicine	Veterans Affairs Research Foundation	MOU for Subsites- CDC
Perencevich, Eli N	Internal Medicine	US Department of Veterans Affairs	Chronic Antibiotic Suppression after Prosthetic Joint Infection
Polyak, Steven	Internal Medicine	AbbVie Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Crohn's Disease who Completed the Studies M14-431 or M14-433
Samaniego, Edgar A	Neurology	MicroVention, Inc.	PHIL DAVF Study
Segar, Jeffrey L	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Fenoldopam to prevent renal dysfunction in indomethacin treated preterm infants
Staber, Janice Marie Rose	Pediatrics	Trinity Partners, LLC	Retrospective chart review of hemophilia A patients with inhibitors treated with rFVIIIFc for ITI
Stoltz, David A	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Origins of Cystic Fibrosis Airway Disease
Thomas, Geb W Karam, Matthew David	Orthopaedics and Rehabilitation	Orthopaedic Research & Education Foundation	Benchmarking Expert Performance to Establish Competency in Wire Navigation
Tsalikian, Eva	Pediatrics	Takeda Development Center Americas, Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Alogliptin Compared With Placebo in Pediatric Subjects With Type 2 Diabetes Mellitus
Vaughan Sarrazin, Mary Susan	Internal Medicine	US Department of Veterans Affairs	36C26318P3305 (636D83057) Rural Veteran's Access to Va and Non-VA Health Care Providers
Washington, M Todd	Biochemistry	US Department of Health & Human Services, National Institutes of Health	Mechanisms of Damaged DNA Replication in Eukaryotes
Weiss, David S	Microbiology	US Department of Health & Human Services, National Institutes of Health	Peptidoglycan binding protein specificity and bacterial cell division
Xue, Hai-Hui	Microbiology	US Department of Health & Human Services, National Institutes of Health	Ezh2 regulates follicular helper T cell differentiation
Zakharia, Yousef	Internal Medicine	Dana-Farber/Partners CancerCare	Phase II study of optimized management of nivolumab based on response in patients with advanced renal cell carcinoma (OMNIVORE)

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AUGUST 2018

PI	Department	Sponsor	Title
Abel, Evan Dale	Internal Medicine	Endocrine Society	Future Leaders Advancing Research in Endocrinology (FLARE): Professional Development
Abrams, Thad Eugene	Internal Medicine	US Department of Veterans Affairs	36C26318P3294 (636D83056) Can Service Dogs Improve Activity and Quality of Life in Veteran's with PTSD - Brian Dake's salary
Ahrens, Richard C	Pediatrics	Vertex Pharmaceuticals, Inc.	A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous or Heterozygous for the F508del Mutation
Anderson, Michael Gary	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Genetic modifiers of Cep290-mediated retinal degeneration
Assouline-Dayan, Yehudith	Internal Medicine	Allakos, Inc.	Clinical Research Protocol AK002-003 A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamic Effect of AK002 in Patients with Eosinophilic Gastritis (EG) and/or Eosinop
Bassuk, Alexander G	Pediatrics	Stanford University	Mechanism-based therapies for photoreceptor degeneration
Bassuk, Alexander G	Pediatrics	Stanford University	Structure and Function of CALPAIN-5
Bathla, Girish	Radiology	Foundation for Sarcoidosis Research	Vessel Wall Imaging in Neurosarcoidosis: Underrecognized, Underdiagnosed and Undertreated
Bollier, Matthew John	Orthopaedics and Rehabilitation	Arthroscopy Association of North America	AANA Sports Med Fellowship Grant
Bruch, Leslie Anne	Pathology	Intersociety Council for Pathology Information, Inc.	Medical Student Interest Group (MSIG) 2016 Grant Program
Channappanavar, Rudragouda	Microbiology	US Department of Health & Human Services, National Institutes of Health	Role of interferon lambda in host protection during aging
Cornell, Robert A	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Regulation of the Melanocyte Lineage by the AP2 Transcription Factor Family
Cullen, Joseph John	Surgery	US Department of Veterans Affairs	Mechanisms of pharmacological ascorbate inhibition of pancreatic cancer metastases
Dayal, Sanjana	Internal Medicine	American Heart Association	Role of gut microbiota in age associated thrombosis
De Mik, David Eric	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course - Basic Principles of Fracture Management
Derdeyn, Colin P	Radiology	University of Cincinnati	Multi-Arm Optimization of Stroke Thrombolysis (MOST) Stroke Trial
Ellingson, Stephanie Jo Kellogg	Radiology	University of Nebraska Medical Center	Introducing Mindful Pause Practice in Sonography Education: A Strategy to Improve Classroom Presence
Furqan, Muhammad	Internal Medicine	Pharmaceutical Research Associates	A Randomized Phase 2 Trial of AM0010 in Combination with Pembrolizumab vs Pembrolizumab Alone as First-Line Therapy in Patients with Metastatic NSCLC whose Tumors have High PD-L1 Expression (CYPRESS-1)
Garje, Rohan	Internal Medicine	Pfizer, Inc.	(IIR) A phase 1b study of combination of Avelumab and Taxane based chemotherapy in platinum refractory or ineligible metastatic urothelial cancer (AVETAX study)
Hillis, Stephen Lawrence	Radiology	US Department of Health & Human Services, National Institutes of Health	Generalized Obuchowski-Rockette Methodology for Analysis of Radiologic Diagnostic Imaging Studies
Horwitz, Phillip Andrew	Internal Medicine	Erasmus University Rotterdam	Synergy between PCI with TAXUS and Cardiac Surgery: SYNTAX Extended Survival (SYNTAXES)
Jabbari, Ali	Dermatology	US Department of Health & Human Services, National Institutes of Health	Defining T helper cell associated cytokines and mechanisms in Alopecia Areata
Jethava, Yogesh Shantilal	Internal Medicine	Janssen Research & Development, Inc.	A phase III randomized, multicenter study of subcutaneous Daratumumab versus active monitoring in subjects with High-risk Smoldering Multiple Myeloma.
Karandikar, Nitin Jayant	Pathology	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Immunotherapeutic Regulatory CD8 T cells in Autoimmune Demyelinating Disease
Kuperman, Samuel	Psychiatry	Neurocrine Biosciences, Inc.	A Phase 2b, Open-Label Safety and Tolerability Study of Optimized Doses of NBI-98854 for the Treatment of Pediatric Subjects with Tourette Syndrome
Leira, Enrique Carlos Adams, Harold P Derdeyn, Colin P Chauhan, Anil Pieper, Andrew A Guierrez, Santiago Samaniego, Edgar A Lentz, Steven Ahmed, Azeemuddin Nugent, Andrew Sean DeJong, Stacey Torner, James C Policeni, Bruno Simmons, Shawn T Hayakawa, Minako Gutmann, Laurie Limaye, Kaustubh S Sharafuddin, Melhem J Horwitz, Phillip Andrew Hasan, David Mathews, Katherine Dianne Tranel, Daniel Thomas Denburg, Natalie Lisa Shim, HyungSub Faine, Brett Anthony Stilley, Joshua David	Neurology	US Department of Health & Human Services, National Institutes of Health	The University of Iowa's Regional Stroke Research Network
Lentz, Steven	Internal Medicine	Apellis Pharmaceuticals, Inc.	An Open Label, Prospective, Study to Assess the Safety, Tolerability, Efficacy and Pharmacokinetics of APL-2 in Patients with Warm Antibody Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD)
Liu, Jing	Internal Medicine	American Heart Association	MicroRNA-204 in Aortic Aneurysmal Disease
Mohr, Nicholas Matthew	Emergency Medicine	Regents of the University of Minnesota	Hyperbaric Oxygen Brain Injury Treatment (HOBIT) Trial: A multicenter, randomized, prospective phase II adaptive clinical trial evaluating the most effective hyperbaric oxygen treatment paradigm for severe traumatic brain injury
Monga, Varun	Internal Medicine	DelMar Pharmaceuticals, Inc.	VAL-083 Phase 3 Study in Temozolomide-Avastin Recurrent GBM (STAR-3): A pivotal randomized, controlled trial of VAL-083 in Patients with recurrent glioblastoma who have failed standard Temozolomide/Radiation Therapy and Bevacizumab
Noiseux, Nicolas Olivier	Orthopaedics and Rehabilitation	MicroPort Orthopedics Inc.	Post-Market Surveillance Study of the Wright Medical Technology Metal-on-
Ohl, Michael	Internal Medicine	Iowa Department of Public Health	Public Health-Partnered Tele-Medical Pre-Exposure Prophylaxis Delivery in a Rural State (TelePrEP)
Phadke, Sneha Deepak	Internal Medicine	Novartis Pharmaceuticals Corporation	BYLieve: A phase II, multicenter, open-label, two-cohort, non-comparative study to assess the efficacy and safety of alpelisib plus fulvestrant or letrozole in patients with PIK3CA mutant, hormone receptor (HR) positive, HER2- negative advanced breast can
Piper, Robert C	Molecular Physiology & Biophysics	US Department of Health & Human Services, National Institutes of Health	Ubiquitin-dependent sorting in endosomes and the TGN
Polyak, Steven	Internal Medicine	AbbVie Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or are Intolerant
Polyak, Steven	Internal Medicine	AbbVie Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or are Intolerant
Reisinger, Heather Schacht	Internal Medicine	US Department of Veterans Affairs	36C26318Q9743 (636D83063) Center for Comprehensive Access & Delivery Research and Evaluation
Ripley, Brittany Michelle	Biochemistry	American Heart Association	Rad18: the master regulator of translesion synthesis
Russo, Andrew F	Molecular Physiology & Biophysics	University of Rochester	CGRP's effect on hearing and balance in a mouse model of migraine
Santillan, Mark Kharim	Obstetrics & Gynecology	American Heart Association	Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia
Schmidt, Gregory Allen	Ophthalmology & Visual Sciences	Eye Bank Association of America	Schmidt-EBAA Lindstrom-Assessing the effects of vasoactive intestinal peptide (VIP) on human corneal endothelial cell bioenergentic activity
Sharathkumar, Anjali Alatkar	Pediatrics	Sangamo Therapeutics, Inc.	A Phase I/II, Open-Label, Adaptive, Dose -Ranging Study to Assess the Safety and Tolerability of SB-525 [ AAV2/6 hFactor VIII Gene Therapy] in Adult Subjects with Severe Hemophilia A
Terry, William Wayne	Cancer Center	Fraternal Order of Eagles	Improving Psych-Social Support for Adolescents and Young Adults with Cancer
Tran, Huy T T	Internal Medicine	Intercept Pharmaceuticals, Inc.	A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Obeticholic Acid in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis
Weiss, Robert M	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Propagation and Resolution of Injury in Calcific Aortic Valve Disease
Weiss, Robert M	Internal Medicine	American Heart Association	Targeting Transient Receptor Potential Cation Channel Subfamily V Member 4 Signaling in Aortic Valve Disease

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JULY 2018

PI	Department	Sponsor	Title
Aldrich, Benjamin Thomas	Ophthalmology & Visual Sciences	Eye Bank Association of America	EBAA - Lindstrom - Assessing the effects of ripasudil, a novel Rho kinase inhibitor, on human corneal endothelial cell bioenergetic activity
Aldrich, Benjamin Thomas	Ophthalmology & Visual Sciences	Eversight	Coenzyme Q10 modulation of mitochondrial function in donor corneal endothelial cells
Assouline-Dayan, Yehudith	Internal Medicine	Allergan Sales, LLC	A 46-week, Double-blind, Placebo-controlled, Phase 3 Study with a 6-week Randomized-withdrawal Period to Evaluate the Safety and Efficacy of Relamorelin in Patients with Diabetic Gastroparesis
Assouline-Dayan, Yehudith	Internal Medicine	Allergan Sales, LLC	A 52-week, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Relamorelin in Patients with Diabetic Gastroparesis
Bernat, John Andrew	Pediatrics	Children's Hospital of Philadelphia	New Approaches in Leukodystrophy-The Myelin Disorders Biorepository and Natural History Project - An Observational Study
Block, Robert I	Anesthesia	National Institutes of Health	General Anesthesia During Early Childhood and Brain Development
Brennan, Timothy J	Anesthesia	Foundation for Anesthesia Education & Research	MSARF Summer Program 2018 - Host Department Application
Carender, Christopher Neil	Orthopaedics and Rehabilitation	DePuy, Inc.	AO Trauma Course North America
Diekema, Daniel James	Internal Medicine	Emory University	Assessment and prevention of bioaerosol dispersal by heater-cooler devices
Dike, Chinenye Rebecca	Pediatrics	Cystic Fibrosis Foundation	CF Pancreatic Cell Function Rescue by VX-770 and VX-809
Dodd, Rebecca Denise	Internal Medicine	US Department of Defense	Mechanisms of NF1+/- Myeloid Cell Function in MPNSTs
Drack, Arlene V	Ophthalmology & Visual Sciences	Medical College of Wisconsin	Defining Structure Function Relationships in Albinism
Dupuy, Adam J	Anatomy & Cell Biology	National Institutes of Health	The role germline polymorphisms on ALL susceptibility
Erickson, Bradley Allan	Urology	National Institutes of Health	Understanding the Role of Local and Systemic Inflammation in Male Urethral Stricture Disease
Evans, Amy Caitlan	Biochemistry	Fight for Sight, Inc.	Fight for Sight 2018-Valdiation of HCN1 Trafficking Partners
Faraci, Frank M	Internal Medicine	National Institutes of Health	Central RAAS and Brain Small Vessel Disease
Fingert, John Harrison	Ophthalmology & Visual Sciences	Glaucoma Foundation	TGF-Fingert-The Role of Autophagy and Mitochondrial Dysfunction in the Pathogenesis of Exfoliation Glaucoma
Fortis, Spyridon	Internal Medicine	ResMed Corp.	Portable Oxygen Concentrator Improvements to Physical Activity, Oxygen Usage, and Quality of Life in Chronic Obstructive Pulmonary Disease Patients using Long-term Oxygen Therapy  (POC-STEP)
Fraer, Mony	Internal Medicine	Omeros Corporation	A Randomized , Double-blind, Placebo-controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IGAN)
Gerke, Alicia	Internal Medicine	Celgene Corporation	A Multicenter, Open-Label Study to Estimate the Effect Sizes of HRCT Endpoints in Response to Glucocorticoid Induction Therapy in Subjects with Pulmonary Sarcoidosis
Gordon, David Jon	Pediatrics	St. Baldrick's Foundation	Reversing Resistance to Inhibitors of Ribonucleotide Reductase (RNR)
Grumbach, Isabella Maria	Internal Medicine	American Heart Association	Novel models of radiation endotheliopathy
Harty, John	Microbiology	National Institutes of Health	Understanding immune regulation in blood-stage malaria
Herwaldt, Loreen A	Internal Medicine	US Department of Health & Human Services, Centers for Disease Control & Prevention	SHEPheRD RFTOP 2018 Domain-1-A001
Huang, Chou-Long	Internal Medicine	University of Texas at Dallas	Glomerular Filtration of Sub-nm Gold Nanoparticles
Johnson, Chris A	Ophthalmology & Visual Sciences	National Academy of Sciences	NASEM Commissioned Paper Agreement
Kaczka, David Walter	Anesthesia	ZOLL Medical Corporation	David Kaczka Paid Consultation to ZOLL Q2
Karwal, Mark William	Cancer Center	NSABP Foundation, Inc.	NSABP PROTOCOL FB-12
Kesler, Kyle Kevin	Orthopaedics and Rehabilitation	Orthopaedic Trauma Association	OTA Fall Residents Comprehensive Fracture Course
Kline, Joel N	Internal Medicine	AstraZeneca Pharmaceuticals LP	A Multicentre, Randomized, Double-Blind, Placebo Controlled, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults with Oral Corticosteroid Dependent Asthma (SOURCE)
Lindsay, Christopher	Orthopaedics and Rehabilitation	Orthopaedic Trauma Association	OTA Fall Residents Comprehensive Fracture Course
Loftus, Randy Wayne	Anesthesia	Draeger Medical GmbH	Evaluation of the efficacy and efficiency of routine cleaning of novel anesthesia machine surfaces
Mathews, Katherine Dianne Gutmann, Laurie Adams, Harold P Nopoulos, Peggy Colleen Shy, Michael E Narayanan, Nandakumar	Neurology	National Institutes of Health	University of Iowa's NeuroNEXT Clinical Research Site
Maury, Wendy	Microbiology	National Institutes of Health	Modeling Filovirus  Infection of and Trafficking through Skin
McCray, Paul B	Pediatrics	Cystic Fibrosis Foundation	A parainfluenza 5 amplifying virus like particle vector for gene delivery
Milhem, Mohammed Mahmoud	Internal Medicine	Ultimovacs AS	A Phase I, Open-Label, Multicenter Study Investigating the Tolerability and Efficacy of UV1 Vaccine in First-Line Malignant Melanoma Patients Planned for Treatment with Pembrolizumab
Milhem, Mohammed Mahmoud	Cancer Center	Iowa Department of Public Health	Melanoma Research and Activities
Miller, Hannah Kay	Biochemistry	American Heart Association	Force-induced apoptosis and the mechanoprotective role of PAK2
Musselman, Catherine Anne	Biochemistry	National Institutes of Health	Molecular mechanisms of histone signaling in a chromatin relevant context
Noureddine, Lama	Internal Medicine	University of Kansas Medical Center Research Institute, Inc.	Burden of Imaging in Renal Cysts
Ochoa Nunez, Luis Alberto	Pediatrics	Leland Stanford Junior University	Ventricular Pacing in Single Ventricle Congenital Heart Disease - A Multicenter International Study
Philibert, Robert Alan	Psychiatry	University of Georgia	Using a Randomized Prevention Trial to Understand the Health Benefits of Supportive Couple Relationships among Rural African American Adults
Polyak, Steven	Internal Medicine	Artizan Biosciences	IBD Microbiome Insights (IBD BIOME)
Schlievert, Patrick Michael	Microbiology	Procter & Gamble Company	TSST-1 Toxin Testing
Shamrock, Alan Gregory	Orthopaedics and Rehabilitation	Medical Device Business Services, Inc (formerly DePuy Synthes)	AO Trauma Course North America
Sigmund, Curt D	Pharmacology	National Institutes of Health	Genetic and Signaling Mechanisms in the Central Regulation of Blood
Song, Long-Sheng	Internal Medicine	American Heart Association	MG53: A double-Edged Sword in Cardiac T-tubule Damage and REpair
Spies, Maria	Biochemistry	US National Science Foundation	EAGER: G4-TIRFM, a platform for massively parallel analysis of non-canonical DNA structures
Stapleton, Jack T	Internal Medicine	Research Foundation for The State University of New York	The effect of HIV and cocaine abuse on semen exosome composition and function
Strack, Stefan	Pharmacology	Ataxia Charlevoix-Saguenay Foundation	Unbiased sacsin client identification and genetic intervention in a mouse model of ARSACS
Thiel, William	Internal Medicine	American Heart Association	Generation of Cardiac Specific Aptamer Ligands
Turvey, Carolyn Louise	Psychiatry	US Department of Health & Human Services, Agency for Healthcare Research & Quality	Development of a Targeted Patient Portal Intervention to Improve Depression Treatment Adherence, Satisfaction, and Outcomes
Weeks, Daniel L	Biochemistry	National Institutes of Health	Amyloids, aggregates and nucleolar activity in Xenopus development
Wilken, Jason Mitchell	Physical Therapy	Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.	MORE Resiliency in the Rehabilitation of Active Duty Service members
Yahr, Timothy Lee Ellermeier, Craig D	Microbiology	National Institutes of Health	25th Annual Midwest Microbial Pathogenesis Conference

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JUNE 2018

PI	Department	Sponsor	Title
Ahrens, Richard C	Pediatrics	Vertex Pharmaceuticals, Inc.	A Post-approval Observational Study to Evaluate the Long-term Effectiveness and Safety of Orkambi in US Patients Who completed Study VX12-809-105 Part A
Anderson, Michael Gary	Molecular Physiology & Biophysics	Glaucoma Foundation	Robust Mouse Models of Exfoliation Glaucoma
Assouline-Dayan, Yehudith	Internal Medicine	Celgene Corporation	Assessment of the Content Validity and Reproducibility of the Dysphagia Daily Symptom Diary (DSD) in Patients with Eosinophilic Esophagitis
Attanasio, Massimo	Internal Medicine	Iowa Fraternal Order of the Eagles	Single Cell Analysis of Senescent Cells After Tubular Injury
Briasoulis, Alexandros	Internal Medicine	University of Kansas Medical Center Research Institute, Inc.	PROVIDE-HF
Cadaret, Linda Marie	Internal Medicine	United Therapeutics Corporation	SOUTHPAW OL
Chitneni, Shobha	Internal Medicine	Genentech, Inc.	PHASE III, OPEN-LABEL, MULTICENTER, RANDOMIZED STUDY EVALUATING THE EFFICACY AND SAFETY OF ATEZOLIZUMAB (MPDL3280A, ANTIPD-L1 ANTIBODY) IN COMBINATION WITH CARBOPLATIN PACLITAXEL OR ATEZOLIZUMAB IN COMBINATION WITH CARBOPLATIN NAB-PACLITAXEL VERSUS CARBO
Ciliberto, Michael Anthony	Pediatrics	GW Pharmaceuticals	A double-blind, randomized, placebo-controlled study to investigate the efficacy and safety of cannabidiol (GWP42003-P, CBD) as add-on therapy in patients with tuberous sclerosis complex who experience inadequately-controlled seizures
Colgan, John David	Internal Medicine	When Everyone Survives Leukemia Research Foundation	The cell-cycle regulator GON4L in acute lymphoblastic leukemia
Cornell, Robert A	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Functional tests of non-coding DNA variants associated with risk for orofacial clefting
Fisher, Rory A	Pharmacology	US Department of Health & Human Services, National Institutes of Health	RGS6 in mesolimbic circuits as a therapeutic target for alcohol use disorders
Fuentes, Ernesto J	Biochemistry	US Department of Health & Human Services, National Institutes of Health	PAS domain and redox regulation of the S. aureus SrrB sensor histidine kinase
Furqan, Muhammad	Internal Medicine	Merck Sharp & Dohme Company	A Phase III, Randomized, Double-blind Trial of Platinum Doublet Chemotherapy +/- Pembrolizumab as Neoadjuvant/Adjuvant Therapy for Participants with Resectable Stage IIB or IIIA NSCLC (Keynote-671)
Gutierrez, Santiago	Neurology	Siemens Medical Solutions USA, Inc.	C-arm Cone Beam Study
Hamzeh, Nabeel Y	Internal Medicine	National Jewish Health	A Prospective Study of T cell Immune-phenotype and Disease Outcome in Pulmonary Sarcoidosis
Hyer, Daniel E	Radiation Oncology	US Department of Health & Human Services, National Institutes of Health	Sharpening the edge in pencil-beam proton therapy: an aftermarket collimation system to better spare normal tissue during radiation treatment
Jiang, Bing-Hua	Pathology	US Department of Health & Human Services, National Institutes of Health	Chromium in carcinogenesis and angiogenesis
Kuehn, Markus H	Ophthalmology & Visual Sciences	Boehringer Ingelheim Pharma GmbH & Co.	Boehringer - Effects of AOC3 Inhibition in Glaucoma
Kuperman, Samuel	Psychiatry	US Department of Health & Human Services, National Institutes of Health	5/7-Collaborative Genomic Studies of Tourette Disorder
Langbehn, Douglas Robert	Psychiatry	University College London	Variability in cognitive impairment in Huntington's disease: the effect of environment on cognitive reserve
Li, Luyuan Park, Brian Ji Hoon	Neurosurgery	Fraternal Order of Eagles	Exploring the effects of radiation therapy on neurotrophic factors
Liu, Ling-Zhi Jiang, Bing-Hua	Pathology	US Department of Health & Human Services, National Institutes of Health	Mechanism of lung cancer resistance to tyrosine kinase inhibitor and radiation treatments
Mathews, Katherine Dianne	Pediatrics	Capricor Therapeutics	A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL EVALUATING THE SAFETY AND EFFICACY OF INTRAVENOUS DELIVERY OF ALLOGENEIC CARDIOSPHERE-DERIVED CELLS IN SUBJECTS WITH DUCHENNE MUSCULAR DYSTROPHY (HOPE-2)
Maury, Wendy	Microbiology	US Department of Health & Human Services, National Institutes of Health	Mechanisms and consequences of Plasmodium/Ebola virus co-infections
Mokadem, Mohamad	Internal Medicine	Iowa Fraternal Order of the Eagles	Jackson Laboratory Genetic Mouse Model (UCP3 KO Mouse)
Monga, Varun	Internal Medicine	St. Baldrick's Foundation	Improve Access to Clinical Trials for AYA with Cancer
Nagpal, Prashant	Radiology	Radiological Society of North America	Comparison of Free-breathing Self-gated 3D Cardiac MRI with Manifold Reconstruction Algorithms and Standard Breath-hold Sequence in Patients with and Without COPD
Narayanan, Nandakumar	Neurology	US Department of Health & Human Services, National Institutes of Health	Timing and dopamine in frontostriatal circuits
Nester, Carla Marie	Pediatrics	Achillion Pharmaceuticals, Inc	A Phase 2, Proof-of-Concept, Randomized, Double-Blinded, Placebo-Controlled Study of ACH-0144471 Treatment for 6 Months in Patients with C3 Glomerulopathy (C3G).
Perlman, Stanley	Microbiology	Kansas State University	Small Molecule Protease Inhibitors against MERS-CoV
Pieper, Andrew A	Psychiatry	Proneurotech, Inc.	Neuroprotective efficacy of P7C3 analogs in blast-mediated traumatic brain injury
Saha, Punam Kumar	Radiology	US Department of Health & Human Services, National Institutes of Health	CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD
Salgado-Pabon, Wilmara	Microbiology	US Department of Health & Human Services, National Institutes of Health	Enterotoxin-Mediated Development of Staphylococcus aureus Infective Endocarditis
Sears, Nathaniel Charles	Ophthalmology & Visual Sciences	IDx, LLC	IDx Study to validate algorithm(s) for predicting thresholded visual field from retinal layer thickness maps in OCTs
Sharafuddin, Melhem J	Surgery	Bard Peripheral Vascular, Inc.	Bard UltraScore Study
Sindt, Christine W	Ophthalmology & Visual Sciences	MDM Optical, LLC	(IIS) MDM Optical LLC-Scleral Lens Design Using Ocular Surface Elevation
Singh, Madhu V	Internal Medicine	Iowa Fraternal Order of the Eagles	2018 Iowa State FOE Grant - Dr. Madhu Singh
Singh, Minati	Internal Medicine	Iowa Fraternal Order of the Eagles	2018 Iowa State FOE Grant - Dr. Minati Singh
Sinn, Patrick Ladd	Pediatrics	US Department of Health & Human Services, National Institutes of Health	Spread and Release of Measles in the Airways
Sivitz, William I	Internal Medicine	Iowa Fraternal Order of the Eagles	Effect of a Mitochondrial-Targeted Antioxidant on Insulin Production by Pancreatic Islet Cells
Starner, Timothy Duane	Pediatrics	Vertex Pharmaceuticals, Inc.	A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of VX-659 in combination with Tezacaftor/Ivacaftor in Subjects With Cystic Fibrosis Who Are Heterozygous for F508del and a Minimal Function Mutation (F/MF)
Starner, Timothy Duane	Pediatrics	Vertex Pharmaceuticals, Inc.	A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del Mutation (F/F)
Thiel, William	Internal Medicine	US Department of Health & Human Services, National Institutes of Health	Deciphering mechanisms of vascular disease with cell and process specific ligands
Vaidya, Jatin Girish	Psychiatry	National Center for Responsible Gambling	Impulsivity in adolescent children with a family history of gambling disorder
Wall, Michael	Ophthalmology & Visual Sciences	EMMES Corporation	VFRC NAION Trial_Emmes
Yan, Ziying	Anatomy & Cell Biology	University of Kansas Medical Center Research Institute, Inc.	Human Bocavirus 1 (Hbov1) Capsid Entry And Intracellular Trafficking Of Polarized Human Airway Epithelium
Yeaman, Charles A	Anatomy & Cell Biology	US Department of Health & Human Services, National Institutes of Health	Regulation of Epithelial Cell Polarity by Ral-Exocyst Complexes
Zakharia, Yousef	Internal Medicine	Clovis Oncology, Inc.	A Phase 2, Open-Label Study of Rucaparib in Patients with Locally Advanced or Metastatic Urothelial Carcinoma (ATLAS)

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MAY 2018

PI	Department	Sponsor	Title
Chitneni, Shobha	Internal Medicine	Genentech, Inc.	A phase II, open-label, multicenter, randomized study to investigate the efficacy and safety of atezolizumab (Anti-PD-L1 Antibody) compared with docetaxel in patients with non-small cell lung cancer after failure with platinum-containing chemotherapy (OAK
Coryell, William	Psychiatry	Quintiles, Inc.	A 6-Month, Multicenter, Double-Blind, Randomized, Flexible-Dose, Parallel-Group Study
Doddapattar, Prakash	Internal Medicine	American Heart Association	Mechanistic role of integrin alpha9beta1 in atherosclerosis
Ferguson, Polly	Pediatrics	CARRA, Inc. Childhood Arthritis and Rheumatology Research Alliance	CARRA- AF Study Coordinator
Gonzalez Bosquet, Jesus	Obstetrics & Gynecology	American Board of Obstetrics and Gynecology	Integrative model to select patients for optimal primary surgical outcomes in high-grade serous ovarian cancer
Harata, Nobutoshi	Molecular Physiology & Biophysics	US Department of Defense, Congressionally Directed Medical Research Program	PR172016 Acute hypoglycemia and inhibitory synaptic transmission in brain neurons
Hefti, Marco Matthias	Pathology	Children's Hospital of Philadelphia	INO Neuroprotection Following Pediatric Cardiac Arrest
Hodgson-Zingman, Denice	Internal Medicine	St. Jude Medical, Inc.	EP Fellowship Grant 2018-19 academic year
Hoffman, Eric	Radiology	National Jewish Health	Genetic Epidemiology of COPD
Hong, Sandy	Pediatrics	CARRA, Inc. Childhood Arthritis and Rheumatology Research Alliance	CARRA- AF Study Coordinator
Hornick, Douglas	Internal Medicine	Insmed, Inc.	A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center Study to Assess the Efficacy, Safety and Tolerability, and Pharmacokinetics of INS1007 Administered Once Daily for 24 Weeks in Subjects with Non-Cystic Fibrosis Bronchiectasis -
Kardon, Randy Herbert	Molecular Physiology & Biophysics	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	VA-PO: Kardon/Hedberg Refine existing methodologies for quantitative and qualitative analysis of mouse to human optic nerve
Kassan, Modar	Internal Medicine	American Heart Association	miR-204/Sirt1 axis induces endothelial dysfunction by targeting vascular serotonin in diabetes/obesity
Long, Jeffrey	Psychiatry	Cleveland Clinic Lerner College of Medicine	Immune Mechanisms Underlying the Neuroprotective Effects of Physical Activity in Human and Mouse Models of Genetic Risk for Alzheimer's Disease
McCray, Paul	Pediatrics	University of Georgia	A parainfluenza virus 5 vector for CRISPR-Cas9 gene edting of CFTR locus
Milhem, Mohammed	Internal Medicine	Genmab A/S	First-in-human, open-label, dose-escalation trial with expansion cohorts to evaluate safety of Axl-specific antibody-drug conjugate (HuMax-AXL-ADC) in patients with solid tumors.
Narayanan, Nandakumar	Neurology	Eli Lilly & Company	Effect of LY3154207 on Cognition in Mild-to-Moderate Parkinson's Disease Dementia
Perencevich, Eli	Internal Medicine	US Department of Veterans Affairs	Checklist to Prevent MRSA Surgical Site Infections
Perencevich, Eli	Internal Medicine	US Department of Veterans Affairs	Measuring Transmissibility of E coli vs Klebsiella and The CREATE MRSA surgical Site infection Bundle 2.0 implementation Study
Schultz, Michael	Radiology	ViewPoint Molecular Targeting, LLC	Targeted Radionuclide Therapy for Metastatic Melanoma
Sharafuddin, Melhem	Surgery	Washington University	C-TRACT TRIAL
Shy, Michael	Neurology	University College London	Muscle MRI in Charcot Marie Tooth disease
Shy, Michael	Neurology	Charcot-Marie-Tooth Association	Molecular Biomarkers for CMT Disease
Strack, Stefan Yuriy Usachev Mark Yorek	Pharmacology	US Department of Health & Human Services, National Institutes of Health	Targeting mitochondrial fission for neuroprotection in diabetic neuropathy
Sylvers, Kelli	Biochemistry	American Heart Association	Lipase inhibition by ANGPTL3 and ANGPTL8
Thomas, Christie	Internal Medicine	Regulus Therapeutics Inc.	A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Efficacy, Pharmacodynamics, and Pharmacokineticsof RG-012 for Injection Administered Every 2 Weeks in Patients with Alport Syndrome
Thomas, Christie	Internal Medicine	Regulus Therapeutics Inc.	A Phase 1, Open-Label Study to Evaluate the Safety, Pharmacodynamics, and Pharmacokinetics of Subcutaneous RG-012 for Injection, Including Its Effect on Renal microRNA-21, in Subjects with Alport Syndrome
Vikram, Ajit	Internal Medicine	American Heart Association	Gut-microbiota regulated vascular miR-204 promotes diabetes-associated endothelial dysfunction
Yadav, Ravi Prakash	Molecular Physiology & Biophysics	Knights Templar Eye Foundation, Inc.	Molecular Mechanisms of AIPL1 and its TPR domain in Leber congenital amaurosis

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APRIL 2018

PI	Department	Sponsor	Title
Abel, E. Dale	Internal Medicine	National Institutes of Health	OPA1 an Estrogen-Mediated Modulator of Platelet Hyperactivation
Cadaret, Linda	Internal Medicine	United Therapeutics Corporation	SOUTHPAW
Chan, Carlos	Surgery	Central Surgical Association Foundation	Effect of Biliary Bacterial Contamination in Peritoneal Metastasis of Peri-Ampullary Cancers
Coryell, William	Psychiatry	Janssen Research and Development, LLC	A Double-blind, Randomized, Psychoactive Placebo-controlled, Study to Evaluate the Efficacy and Safety of 3 Fixed Doses (28 mg, 56 mg and 84 mg) of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms
Erickson, Bradley	Urology	Urotronic, Inc.	ROBUST II Clinical Study Re-Establishing Of Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
Farooq, Umar	Internal Medicine	Kite Pharma, Inc.	A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy of Axicabtagene Ciloleucel vs Standard of Care Therapy in Subjects with Relapsed / Refractory Diffuse Large B Cell Lymphoma (ZUMA-7)
Gutierrez, Santiago	Neurology	Medtronic, Inc.	Medical Education Neurovascular- Medtronic
Hefti, Marco	Pathology	Children's Hospital of Philadelphia	Ischemix SRA Large Animal PoC Efficacy Trial for CMX-2043
Hrabe, Jennifer	Surgery	Entac Medical, Inc.	Spectral Density in GI Impairment
Idiga, Sharon	Pharmacology	American Heart Association	Novel Endocrine Circuit Regulating Sugar Satiety
Milhem, Mohammed	Internal Medicine	Mayo Clinic	Phase 2 Clinical Trials Program for Experimental Therapeutics Clinical Trials Network
Miller, Benjamin	Orthopaedics and Rehabilitation	Cleveland Clinic Foundation	Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma
Newell, John	Radiology	Columbia University	Subclinical interstitial lung disease in MESA and FAR-ILD
Noterman, Maria	Psychiatry	National Institutes of Health	A Novel Role of Cav1.2 in Mitochondria
Noureddine, Lama	Internal Medicine	Hope Medical Enterprises, Inc.	Observational Follow-up to ST-001 Calciphylaxis Pain Treatment with Intravenous Sodium Thiosulfate
Ohl, Michael	Internal Medicine	Gilead Sciences, Inc.	A brief, pragmatic experiment to determine the feasibility of a public-health-partnered tele-pharmacist model for PrEP delivery in a rural state
Perencevich, Eli	Internal Medicine	US Department of Veterans Affairs	Work for the Center for Comprehensive Access & Delivery Research and Evaluation
Ponce, Jessica	Internal Medicine	National Institutes of Health	Dual Roles of Cyclin C in Heart Disease
Sapouckey, Sarah	Pharmacology	American Heart Association	Mechanisms of the Arcuate Nucleus Leptin-Angiotensin Interaction in the Control of Metabolism
Schmidt, Warren	Internal Medicine	Conatus Pharmaceuticals, Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects with Decompensated Non-Alcoholic Steatohepatitis (NASH) Cirrhosis
Sieren, Jessica	Radiology	Exemplar Genetics	Exemplar Genetics
Stapleton, Jack	Internal Medicine	Health Resources & Services Administration	OP EARLY INTERVENTION SERVICES WITH RESPECT TO HIV DISEASE
Swenson, Andrea	Neurology	Massachusetts General Hospital	Phase II Clinical Trial to Evaluate Safety, Tolerability, and Biomarker Engagement of AMX0035 in Patients with ALS
Tsalikian, Eva	Pediatrics	Ascendis Pharma A/S	A Multicenter, Phase 3, Open-Label, 26-Week Trial Investigating the Safety, Tolerability and Efficacy of TransCon hGH Administered Once Weekly in Children with Growth Hormone Deficiency (GHD
Wibbenmeyer, Lucy	Surgery	Stratatech	A Phase III Open-Label, Controlled Randomized, Multicenter Study Evaluating the Efficacy and Safety of Stratagraft Skin Tissue in Promoting Autologous Skin Tissue Regeneration of Complex Skin Defects Due to Thermal Burns that Contain Intact Dermal Element
Wilken, Jason	Physical Therapy	Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.	The BADER Consortium: Maximizing Out Patient Rehabilitation Effectiveness (MORE)
Winokur, Patricia	Institute for Clinical and Translational Science	National Institutes of Health	The University of Iowa Clinical and Translational Science Award
Zakharia, Yousef	Internal Medicine	Dana-Farber/Partners CancerCare	A Phase II Study of TAK-228 in patients with previously treated metastatic renal cell carcinoma
Zakharia, Yousef	Internal Medicine	Astellas Pharma Global Development, Inc.	A phase I study of ASP8374, an Immune Checkpoint Inhibitor, in subjects with advanced solid tumors.
Zakharia, Yousef	Internal Medicine	Calithera BioSciences, Inc.	A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study Comparing CB-839 in Combination with Everolimus (CBE) vs. Placebo with Everolimus (PboE) in Patients with Advanced or Metastatic Renal Cell Carcinoma (RCC)
Zakharia, Yousef	Internal Medicine	Hoosier Cancer Research Network, Inc.	Single Arm Phase II Study of Ipilimumab and Nivolumab as Adjuvant Therapy for Resected Mucosal Melanoma (SALVO study)
Zarei, Sanam	Molecular Physiology & Biophysics	Howard Hughes Medical Institute	Can Increasing CDP-Ribitol by ISPD Gene Transfer Improve Dystroglycan Glycosylation and Muscle Function in Limb Girdle Muscular Dystrophy 2I (LGMD2I) Mice?

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MARCH 2018

PI	Department	Sponsor	Title
Assouline-Dayan, Yehudith	Internal Medicine	Allergan Sales, LLC	A 12 WEEK, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED, PHASE 3 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF RELAMORELIN IN PATIENTS WITH DIABETIC GASTROPARESIS
Assouline-Dayan, Yehudith	Internal Medicine	Shire Human Genetic Therapies, Inc.	A Phase 3, Multicenter, Open-Label Continuation Study with Budesonide Oral Suspension (BOS) for Adolescent and Adult Subjects with Eosinophilic Esophagitis (EoE)
Bender, David	Obstetrics & Gynecology	GOG Foundation	A Phase III, MULTICENTER, RANDOMIZED, placebo-controlled Study OF Atezolizumab Versus Placebo IN COMBINATION WITH Paclitaxel, carboplatin, and Bevacizumab for PATIENTS WITH Newly diagnosed stage III/IV ovarian, ...
Bhama, Jay	Surgery	St. Jude Medical Business Services, Inc.	Investigation of HearTMatE2 LVAD with sEnsing CardioMEMs Technology in Heart Failure Patients (INTELLECT2-HF)
Cadaret, Linda	Internal Medicine	Duke Clinical Research Institute	VICTORIA HF Registry
Chatterjee, Snehajyoti	Molecular Physiology & Biophysics	Nellie Ball Trust	Investigating the role of the schizophrenia-associated gene Nr4A2 in cognition using single-neuron RNA sequencing
Choi, Kent	Surgery	Octapharma Pharmazeutika	A phase III, randomized, double-blind, multicenter study to assess the efficacy and safety of OCTAPLEX, a four-factor prothrombin complex concentrate (4F-PCC), compared to the 4F-PCC Beriplex P/N (Kcentra), for the reversal of vitamin K antagonist induced
Claflin, Kristin	Pharmacology	National Institutes of Health	Identification of a novel neural circuit regulating energy expenditure and glucose homeostasis
Comellas, Alejandro	Internal Medicine	GlaxoSmithKline LLC	A randomized, double-blind, Sponsor open, placebo-controlled, 52 week study evaluating the effect of danirixin (GSK1325756) on lung function and health related quality of life in participants with mild to moderate Chronic Obstructive Pulmonary Disease (CO
Comellas, Alejandro	Internal Medicine	COPD Foundation	RETHINC
Derdeyn, Colin	Radiology	Penumbra, Inc.	Penumbra DSMB Consulting Services Agreement
Dolan, Lori	Orthopaedics and Rehabilitation	Green Sun Medical	Green Sun Medical Methods Consulting
Dunn-Johnson, Camille	Otolaryngology - Head & Neck Surgery	Cochlear Americas	Adult Cochlear Implant Candidacy & Outcomes:  a Retrospective Analysis
Fraer, Mony	Internal Medicine	Arbor Research Collaborative for Health	Peritoneal Dialysis Outcomes and Practice Patterns Study, 2017-2020
Goodheart, Michael	Obstetrics & Gynecology	University of Chicago	Phase II Trial of Metformin Subcontract- U of Chicago
Grumbach, Isabella	Internal Medicine	US Department of Veterans Affairs	Calmodulin kinase II inhibition as novel molecular treatment of hypertension
Gutmann, Laurie	Neurology	Charcot-Marie-Tooth Association	Early Phase Treatment Trials of CMT2A
Hadlandsmyth, Katherine	Anesthesia	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain
Hammond, Donna	Anesthesia	National Institutes of Health	Mechanistic Studies of the Natural Product Nicotinamide Riboside for Relief of Painful Sensory Neuropathy
Harland, Karisa	Emergency Medicine	Iowa Department of Public Health	Sexual Violence Prevention Evaluation
Haskell, Sarah	Pediatrics	National Institutes of Health	Impact of disruptions in the serotonin system on cardiac development
Ho, Beng Choon	Psychiatry	Nellie Ball Trust	Brain Neuroimaging Correlates of Schizophrenia Polygenic Risk Score
Horwitz, Phillip	Internal Medicine	Edwards Lifesciences LLC	EARLY TAVR
Huang, Chou-Long Sigmund, Curt	Internal Medicine	National Institutes of Health	Iowa Training Program in Kidney and Hypertension Research
Jalal, Diana	Internal Medicine	AstraZeneca Pharmaceuticals LP	A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease
Knudson, C Michael	Pathology	Terumo Corporation	Clinical Effectiveness of Standard Versus Mirasol-treated Apheresis Platelets in Patients with Hypoproliferative Thrombocytopenia (MIPLATE Trial)
Law, Ian	Pediatrics	Rock for the Heart Foundation	Atrial Tachycardia Pacing Therapy in Congenital Heart (AT-PATCH)
Leira, Enrique	Neurology	University of Cincinnati	ARCADIA study
Lieberman, Scott	Pediatrics	National Institutes of Health	Cytokines driving T cell dysregulation in lacrimal gland autoimmunity
Link, Brian Krall	Cancer Center	Mayo Clinic	Genetic Predictors of Early Clinical Failure in Diffuse Large B Cell Lymphoma
Liu, Ling-Zhi	Pathology	American Cancer Society	Chromium-Mediated Signaling Pathways in Carcinogenesis
Liu, Ling-Zhi	Pathology	National Institutes of Health	New Mechanism of Arsenic Carcinogenesis
Magnotta, Vincent	Radiology	National Institutes of Health	Research 3T MRI Connectome Upgrade
Mathews, Katherine	Pediatrics	Acceleron Pharma, Inc.	A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ACE-083 in Patients with Facioscapulohumeral Muscular Dystrophy
Milhem, Mohammed	Internal Medicine	TESARO, Inc.	A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors
Milhem, Mohammed	Internal Medicine	Novartis Pharmaceuticals Corporation	Modular phase 2 study to link combination immune-therapy to patients with advanced solid and hematologic malignancies - Module 9:  PDR001 plus LAG525 for patients with advanced solid and hematologic malignancies
Parker, Krystal	Psychiatry	Nellie Ball Trust	Targeting comorbid depression in schizophrenia with cerebellar stimulation
Paulsen, Jane	Psychiatry	National Institutes of Health	Preparing for preventive clinical trials in Huntington's disease
Polgreen, Philip	Internal Medicine	US Department of Veterans Affairs	An M-health Intervention to Increase the Activity Levels of Rural Veterans (MapTrek)
Price, David	Biochemistry	National Institutes of Health	RNA Polymerase II Elongation Control
Reinking, Benjamin	Pediatrics	Janssen Research & Development, Inc.	A Prospective, Open-Label, Active-Controlled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Rivaroxaban for Thromboprophylaxis in Pediatric Subjects 2 to 8 Years of Age after the Fontan Procedure
Singh, Namrata	Internal Medicine	Duke University	A Randomized, double-blind, placebo-controlled, multicenter, phase III efficacy and safety study of subcutaneous anakinra (Kineret) in patients with Still's disease (SJIA and AOSD) followed by an open-label extension.
Stevens, Hanna	Psychiatry	Nellie Ball Trust	The Effects of Redox Dysregulation on Cortical Interneuron Development and Schizophrenia-like Behaviors
Swenson, Andrea	Neurology	Cytokinetics, Inc.	Cytokinetics - CY-5022
Tyler, Richard	Otolaryngology - Head & Neck Surgery	University of Southern California	Hyperacusis focus groups
Vaughan Sarrazin, Mary	Internal Medicine	US Department of Veterans Affairs	Conduct work to enhance the innovative data analysis and management capabilities and techniques in Iowa City
Velez, Gabriel	Ophthalmology	National Institutes of Health	Structure-function studies of Calpain-5 in hereditary uveitis
Wilson, Mary	Internal Medicine	US Department of Veterans Affairs	The Role of Exosomes in the Pathogenesis of Leishmaniasis

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FEBRUARY 2018

PI	Department	Sponsor	Title
Cadaret, Linda	Internal Medicine	United Therapeutics Corporation	ADAPT
Chauhan, Anil	Internal Medicine	National Institutes of Health	Targeting Pyruvate Kinase M2: A novel strategy to combat thrombo-inflammation
Comellas, Alejandro	Internal Medicine	Emergent Biosolutions, Inc.	A Randomized, Double-Blind, Placebo-Controlled Dose Ranging Study
DeCorte, Benjamin	Neurology	National Institutes of Health	Dopaminergic regulation of striatal ensembles during cognitive performance: Implications for Parkinson's disease
Erickson, Bradley	Urology	Boston Scientific Corporation	2018-2019 Urology Fellowship
Fingert, John Anderson, Michael Scheetz, Todd	Ophthalmology & Visual Sciences	National Institutes of Health	Exome Studies of Pigmentary Glaucoma
Flynn, Ryan	Radiation Oncology	Elekta, Inc.	Elekta's Usability Testing Activities at the University of Iowa
Gordon, David	Pediatrics	National Institutes of Health	Gene expression signature based screening in Ewing sarcoma
Grobe, Justin	Pharmacology	American Heart Association	Hypothalamic mechanisms of cardiometabolic and obstetric disease
Hansen, Marlan Guyman, C Allan	Otolaryngology - Head & Neck Surgery	National Institutes of Health	Reduction of intracochlear fibrosis and bacterial infection using photopolymerized durable zwitterionic coatings on cochlear implant biomaterials
Harrison, Heather Thomas, Geb	Orthopaedics and Rehabilitation	Pediatric Orthopaedic Society of North America	The Design and Validation of a Wire Natigation Simulator for Pediatric Supracondylar Humerus Fractures
Hitchon, Patrick	Neurosurgery	Pfizer, Inc.	A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Staphylococcus Aureus 4-Antigen Vaccine (SA4Ag) in Adults Undergoing Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation
Hoffman, Eric	Radiology	University of California, San Francisco	SPIROMICS II: Biological underpinnings of COPD heterogeneity and progression
Irani, Kaikobad	Internal Medicine	US Department of Veterans Affairs	SIRTUIN1-mediated inhibition of P66shc lysine acetylation as a novel treatment for diabetic vasculopathy
Levy, Barcey	Family Medicine	Oregon Health & Science University	A cluster-randomized trial comparing team-based versus primary care clinician-focused advance care planning in practice-based research networks
Mangalam, Ashutosh	Pathology	National Institutes of Health	Linking diet, gut microbiota and autoimmune disease: Bacteria induced phytoestrogen metabolites impact immune function in Experimental Autoimmune Encephalitis
Milhem, Mohammed	Internal Medicine	Idera Pharmaceuticals, Inc.	A Phase 1/2 Study to Assess the Safety and Efficacy of Intratumoral IMO-2125 in Combination with Ipilimumab or Pembrolizumab in Patients with Metastatic Melanoma
Nance, Christopher	Neurology	Vertex Pharmaceuticals, Inc.	Clinical Trial - Study drug VX16-150-102
Nester, Carla	Pediatrics	Alexion Pharmaceuticals, Inc.	A PHASE 3, OPEN-LABEL, MULTICENTER STUDY OF ALXN1210 IN CHILDREN AND ADOLESCENTS WITH ATYPICAL HEMOLYTIC-UREMIC SYNDROME (aHUS)
Nester, Carla	Pediatrics	ChemoCentryx, Inc.	A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of Avacopan (CCX168) in Patients with C3 Glomerulopathy
Noureddine, Lama	Internal Medicine	Hope Pharmaceuticals	A Phase 3, Intravenous Sodium Thiosulfate for Acute
Packer, Hans Williams, Aislinn	Psychiatry	Nellie Ball Trust	Analyzing the functional consequences of a genetic risk factor for schizophrenia using genome editing of patient-derived stem cells
Purnell, Benton	Neurology	National Institutes of Health	Determining the effect of circadian phase on seizure induced respiratory arrest and death
Sharafuddin, Melhem	Surgery	GE Healthcare	Parallel-Group, Placebo-Controlled Randomized Study Investigating the Effect of Intravenous Iso-osmolar Iodinated Contrast Material Iodixanol (Visipaque Injection 320 mgI/mL) on Renal Function in Adults with Chronic Kidney Disease (CKD) Stage III or Stage
Solimeo, Samantha	Internal Medicine	US Department of Veterans Affairs	Identifying Barriers to Implementation and Spread of Specialty Care Telehealth PACT Serving Rural Veterans
Tanas, Munir	Pathology	US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center	Upstream regulation of TAZ and YAP in sarcomas: towards combinatorial
Varga, Steven	Microbiology	Iowa State University	Nanoparticle-based vaccination against RSV
Vyas, Yatin	Pediatrics	National Institutes of Health	Role of WASp in Golgi dispersal response to DNA damage in lymphocytes
Weigel, Ronald	Surgery	University of Ghana	WACCBIP Wellcome Trust Deltas Student-Visitor Fellowship Award
Wemmie, John	Psychiatry	National Institutes of Health	Basolateral amygdala circuits in defensive behavior regulation
Zhang, Jian	Pathology	Ohio State University	Regulation of T Follicular Helper Cells in SLE by E3 Ubiquitin Ligase Cbl-b

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JANUARY 2018

PI	Department	Sponsor	Title
Adams, Christopher	Internal Medicine	US Department of Veterans Affairs	Prevention and Treatment of Skeletal Muscle Atrophy
Ahrens, Richard	Pediatrics	Proteostasis Therapeutics, Inc.	A Multi-Center, Randomized, Placebo-Controlled, Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, & Drug Interactions of PTI-801 in Healthy Volunteers, & Safety, Tolerability, & Pharmacokinetics in Subjects with CF
Allen, Bryan	Radiation Oncology	Gateway for Cancer Research	Pharmacological Ascorbate Combined with Radiation and Temozolomide in GBM
Allen, Lee-Ann	Internal Medicine	National Institutes of Health	Francisella tularensis reprograms human neutrophils
Anderson, Carryn	Radiation Oncology	Soligenix, Inc.	A Pivotal, Double-Blind, Randomized, Placebo-Controlled, Multinational Study Of Sgx942 (Dusquetide) For The Treatment Of Oral Mucositis In Patients Being Treated With Concomitant
Artemyev, Nikolai	Molecular Physiology & Biophysics	National Institutes of Health	Molecular Mechanisms of Photoreceptor G Protein Signaling
Bender, David	Obstetrics & Gynecology	Regeneron Pharmaceuticals, Inc.	GOG-3016 / R2810-ONC-1676
Chitneni, Shobha	Internal Medicine	Genentech, Inc.	A phase III, open-label, randomized study of atezolizumab (MPDL3280A, anti-PD-L1 antibody) in combination with carboplatin+paclitaxel with or without bevacizumab compared with carboplatin+paclitaxel+bevacizumab in chemotherapy-naive patients with stage IV
Collins, Laura	Pathology	Mallinckrodt Pharmaceuticals	CELLEX Access Route and Diagnosis Program
Davis, Benjamin	Internal Medicine	AstraZeneca Pharmaceuticals LP	A Multicenter, Randomized, Double-blind, Parallel Group, Placebo controlled, Phase 3b Study to Evaluate the Safety and Efficacy of Benralizumab 30 mg sc in Patients with Severe Asthma Uncontrolled on Standard of Care Treatment
Dejong, Stacey	Physical Therapy	University of California, Irvine	Genetic variation, stress, and functional outcomes after stroke rehabilitation
Norris, Andrew Engelhardt, John	Pediatrics	National Institutes of Health	Splanchno-Hormonal Mechanisms of Cystic Fibrosis Related Diabetes
Engelhardt, John	Anatomy & Cell Biology	Cystic Fibrosis Foundation	Modulating Regenerative Abilities of Airway Stem Cells for CF Therapy
Engelhardt, John	Anatomy & Cell Biology	Talee Bio, Inc.	TaleeBio - TL-101 Phase 1 Sponsored Research
Hamzeh, Nabeel	Internal Medicine	National Jewish Health	Epigenetic Regulation of Altered T-cell Immunity in Sarcoidosis
Hamzeh, Nabeel	Internal Medicine	National Jewish Health	Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency
Hamzeh, Nabeel	Internal Medicine	National Jewish Health	Role of T-bet+CD11 c+ B Cells in Sarcoidosis
Huang, Chou-Long	Internal Medicine	University of Texas Southwestern Medical Center	Preventive Hypertension and Sympathetic Overactivation by Targeting Phosphate
Huang, Chou-Long	Internal Medicine	Boehringer Ingelheim Pharmaceuticals, Inc.	Boehringer Ingelheim Pharmaceuticals Research Project #2
Krysan, Damian	Pediatrics	University of Pennsylvania	A. mutans-C Albicans Interactions syngergize teh virulence of cariogenic biofilms
Kuperman, Samuel	Psychiatry	Neurocrine Biosciences, Inc.	A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose-Optimization Study to Assess the Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects with Tourette Syndrome
Larson Ode, Katie	Pediatrics	Regents of the University of Minnesota	The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic CF Patients
Lizarraga, Ingrid	Cancer Center	Alliance Foundation Trials, LLC	Comparison of Operative to Monitoring and Endocrine Therapy (COMET) Trial for low risk DCIS: A Phase III Prospective Randomized Trial
Macfarlane, Donald	Internal Medicine	Shire plc	Pilot study of lexeme-based medical note creation for patients with hemophilia
Magalhaes-Silverman, Margarida	Internal Medicine	Incyte Corporation	A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination with Corticosteroids for the Treatment of First-Line Acute Graft-Vs-Host Disease.
Mathews, Katherine	Pediatrics	Reata Pharmaceuticals, Inc.	A PHASE 2 STUDY OF THE SAFETY, EFFICACY, AND PHARMACODYNAMICS OF RTA 408 IN THE TREATMENT OF FRIEDREICH'S ATAXIA
Mathews, Katherine	Pediatrics	Takeda Development Center Americas, Inc.	A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm Study to Evaluate Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adult Subjects With Friedreich Ataxia
Nauseef, William	Internal Medicine	National Institutes of Health	Determinants of human neutrophil fate after phagocytosis
Polyak, Steven	Internal Medicine	AbbVie, Inc.	A Phase 3 Multicenter, Open-Label Extension (OLE) Study to Evaluate the Long-Term Safety and Efficacy of ABT-494 in Subjects with Ulcerative Colitis (UC)
Rauckhorst, Adam	Biochemistry	American Diabetes Association	Regulation of Hepatic Glucose Metabolism by a Candidate Mitochondrial Glutamine Carrier
Sah, Rajan	Internal Medicine	American Diabetes Association	SWELL1 regulation of -cell excitability and insulin secretion
Sanchez, Antonio	Internal Medicine	AbbVie, Inc.	A Single Arm, Open-label Study Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment Naive Adults with Chronic Hepatitis C Virus (HCV) Genotype 1, 2, 4, 5 or 6 Infection and Compensated Cirrhosis
Schnieders, Michael	Biochemistry	US National Science Foundation	CAREER: Chemical Theory for the Protein Crystal Folding Problem
Sebag, Julien	Molecular Physiology & Biophysics	National Institutes of Health	Investigating the requirement of MRAP2 for ghrelin function
Sharathkumar, Anjali	Pediatrics	Bioverativ, Inc.	A Non-controlled, Open-Label, Multicenter, Study of Efficacy of
Staber, Janice	Pediatrics	Bioverativ, Inc.	EXTEN-A
Tarini, Beth	Pediatrics	University of Colorado Denver	NewSTEPS360
Wall, Michael	Neurology	Icahn School of Medicine at Mount Sinai	Surgical IIH Treatment Trial
Wei, Shunguang	Internal Medicine	National Institutes of Health	Targeting TACE, a novel approach to the treatment of sympathetic excitation in heart failure.
Yang, Ling	Anatomy & Cell Biology	American Diabetes Association	Mechanisms underlying itrosylation-mediated dysregulation of hepatic autophagy in obesity

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DECEMBER 2017

PI	Department	Sponsor	Title
Ahrens, Richard	Pediatrics	Savara Pharmaceuticals	A Phase III, randomized, double-blind, placebo-controlled study of AeroVanc for the treatment of persistent methicillin-resistant Staphylococcus aureus lung infection in cystic fibrosis patients
Cadaret, Linda	Internal Medicine	Actelion Clinical Research, Inc.	SERENADE:  A multi-center, double-blind, placebo-controlled Phase 2b study to evaluate the efficacy and safety of macitentan in subjects with heart failure with preserved ejection fraction and pulmonary vascular disease
Chauhan, Anil	Internal Medicine	American Heart Association	Novel Mechanisms linking thromosis and inflammation
Fick, Andrea	Obstetrics & Gynecology	Telligen Community Initiative	Sonographer Training for Telemedicine for High-Risk Pregnancies
Fiedorowicz, Jess	Psychiatry	Washington University	Resource Development to Facilitate sIRB Review for Multi-site Research
Gantz, Bruce	Otolaryngology - Head & Neck Surgery	NIH	Iowa Cochlear Implant Clinical Research Center VII
Grumbach, Isabella	Internal Medicine	NIH	Mitochondrial CaMKII drives smooth muscle migration and neointimal hyperplasia
Gurung, Prajwal	Internal Medicine	NIH	Elucidating cellular and molecular mechanisms regulating SHP1-mediated inflammatory skin disease
Hansen, Marlan	Otolaryngology - Head & Neck Surgery	Decibel Therapeutics, Inc.	Collaboration with Decibel
Hirsch, Raphael	Pediatrics	NIH	Molecular and Cellular Research to Advance Child Health
Horwitz, Phillip	Internal Medicine	Novartis Pharmaceuticals Corporation	PARADISE-MI
Imai, Yumi	Internal Medicine	American Diabetes Association	Regulation of insulin secretion by lipid droplet proteins!
Krysan, Damian	Pediatrics	NIH	Complex haploinsufficiency based genetic analysis of C.albicans pathhogenesis
Larson, Robert	Internal Medicine	NIH	Cardiac Sensory-Sympathetic-Angiotensinergic Mechanisms in Hypertrophic Cardiomyopathy
Lentz, Steven	Internal Medicine	Novo Nordisk, Inc.	Alleviate 1
Martinez, Denise	Medicine Administration	Robert Wood Johnson Foundation	Summer Health Professions Education Program
Meier, Jeffery  Price, David	Internal Medicine	NIH	Transcriptional Mechanisms Controlling HCMV Infection
Paulsen, Jane	Psychiatry	CHDI Foundation, Inc.	HDClarity
Polyak, Steven	Internal Medicine	TARGET PharmaSolutions	A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease
Robertson, Janice	Molecular Physiology & Biophysics	NIH	Debugging eukaryotic membrane protein expression in E. coli using single-molecule fluorescence microscopy
Shaffer, Joseph	Radiology	Brain & Behavior Research Foundation	THE EFFECTS OF CEREBELLAR STIMULATION ON FUNCTIONAL ACTIVITY AND CONNECTIVITY IN SCHIZOPHRENIA
Sharathkumar, Anjali	Pediatrics	Washington University	Heartland Sickle Cell Disease Network
Strack, Stefan	Pharmacology	Jordan's Guardian Angels	Deciphering molecular pathogenesis and developing a mouse models of PPP2R5D mutations
Swenson, Andrea	Neurology	Flex Pharma, Inc.	Flex Pharma clinical trial drug Flex-787-203
Wall, Michael	Ophthalmology & Visual Sciences	Icahn School of Medicine at Mount Sinai	SiihTT VFRC-Surgical IIH Treatment Trial
Yan, Ziying	Anatomy & Cell Biology	Cystic Fibrosis Foundation Therapeutics, Inc.	Novel Parvovirus Vector for Cystic Fibrosis Gene Therapy

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NOVEMBER 2017

PI	Department	Sponsor	Title
Abushahin, Laith	Internal Medicine	Merck Sharp & Dohme Company	A Phase III Randomized Open-label Study of Single Agent Pembrolizumab vs Physicians' Choice of Single Agent Docetaxel, Paclitaxel, or Irinotecan in Subjects with Advanced/Metastatic Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus that have Pro
Ahern, Christopher	Molecular Physiology & Biophysics	NIH	The Facility for Atomic Mutagenesis
Bernat, John	Pediatrics	Protalix Biotherapeutics	A Phase 3, Open Label, Switch Over Study to Assess the Safety, Efficacy and Pharmacokinetics of pegunigalsidase alfa (PRX-102) 2 mg/kg Administered by Intravenous Infusion Every 4 Weeks for 52 weeks in Patients with Fabry Disease Currently Treated with En
Cadaret, Linda	Internal Medicine	Actelion Pharmaceuticals, Ltd.	OPsumit Historical USers cohort study (OrPHeUS), a Multicenter, retrospective chart review of first-time Opsumit (macitentan) users in the United States
Davis, Andrew	Otolaryngology - Head & Neck Surgery	American Academy of Otolaryngology-Head and Neck Surgery Foundation	SOD Mimics Enhace Chemoradiation Responses of HNSCC via Oxidative Stress
Fairley, Janet	Dermatology	Regents of the University of California, San Francisco	A Phase I, Open-Label, Multicenter Trial Exploring the Safety and Tolerability of Autologous Polyclonal Regulatory T Cell Therapy in Adults with Active Pemphigus
Gantz, Bruce	Otolaryngology - Head & Neck Surgery	Cochlear Americas	Association Between Intra-Operative Cochlear Response Telemetry and Hearing Preservation (CREST)
Hendrickson, Nathan Willey, Michael	Orthopaedics and Rehabilitation	Orthopaedic Trauma Association	Perioperative Screening and Nutritional Supplementation in Orthopaedic Trauma Patients
Hoffman, Eric	Radiology	National Jewish Health	(1 of 3) Genetic Epidemiology of COPD
Lentz, Steven	Internal Medicine	Novo Nordisk, Inc.	Explorer 4
Long, Jeffrey Mills, James	Psychiatry	CHDI Foundation, Inc.	Modeling progression in Huntington's disease: analysis and validation across multiple studies
Mathews, Katherine Trout, Christina	Pediatrics	Parent Project Muscular Dystrophy	PPMD CDCC Liaison Grant 2018
Murray, Jeffrey	Institute for Clinical and Translational Science	Burroughs Wellcome Fund	BWF Physician-Scientist Institutional Award Planning Grant Application
Shy, Michael	Neurology	Flex Pharma, Inc.	Flex-Pharma Clinical trial of study drug Flex-787-204
Sivitz, William	Internal Medicine	George Washington University	Glycemia Reduction Approaches for Diabetes: A Comparative Effectiveness Study (GRADE)
Stone, Edwin	Ophthalmology & Visual Sciences	Grand Chapter of Iowa Order of the Eastern Star	Sramek Age-Related Macular Degeneration Fund
Stone, Edwin	Ophthalmology & Visual Sciences	Renaissance Charitable Foundation Inc.	Diagnostics and Surgical Treatment Fund for Retinal Diseases
Wood, Kelly	Pediatrics	Seattle Children's Research Institute	Pediatric Quality Measures Program- Dissemination and Implementation of Child Health quality Measures Cooperative Research Grant
Yang, Ling	Anatomy & Cell Biology	NIH	Integration of Inflammatory Signaling and the Unfolded Protein Response by Nitrosylation Signaling in Obesity
Zakharia, Yousef	Internal Medicine	Merck Sharp & Dohme Company	A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Pembrolizumab as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy
Zakharia, Yousef	Internal Medicine	NewLink Genetics Corporation	A Phase 2/3 (Adaptive Design) Study of the Concomitant Administration of Indoximod or Placebo plus Pembrolizumab or Nivolumab in Adult Patients with Unresectable Stage III or Stage IV Malignant Melanoma

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OCTOBER 2017

PI	Department	Sponsor	Title
Abel, Ted	Molecular Physiology & Biophysics	University of Pennsylvania	Sleep/Wake Fragmentation with Age: Molecular Mechanisms
Ahmad, Ferhaan	Internal Medicine	University of Kentucky	Role of myocyte Na+ dysregulation in diabetic heart disease
Assouline-Dayan, Yehudith	Internal Medicine	Seres Therapeutics, Inc.	AN OPEN-LABEL EXTENSION OF STUDY SERES-012 EVALUATING SER-109 IN ADULT SUBJECTS WITH RECURRENT CLOSTRIDIUM DIFFICILE INFECTION (RCDI)
Badovinac, Vladimir	Pathology	University of Minnesota	Alterations in CD4 T cells during sepsis
Bernat, John	Pediatrics	Protalix Biotherapeutics	A Multi Center Extension Study of PRX-102 Administered by Intravenous Infusions Every 2 Weeks for up to 60 Months to Adult Fabry Patients
Cadaret, Linda	Internal Medicine	Bayer Healthcare AG	PANACHE
Cadaret, Linda	Internal Medicine	Amgen, Inc.	GALACTIC-HF
Ciliberto, Michael	Pediatrics	GW Pharmaceuticals	Amendment # 3 GW Pharmaceuticals - An open label extension study to investigate the safety of cannabidiol (GWP42003-P; CBD) in children and adults with inadequately controlled Dravet or Lennox-Gastaut Syndromes
Coryell, William	Psychiatry	University of Michigan	Electronic Bridge to Mental Health (eBridge) for College Students_Supplement
Diekema, Daniel	Pathology	bioMerieux, Inc.	VITEK 2 and VITEK 2 Compact AF04 Antifungal Susceptibility Tests
Engelhardt, John	Anatomy & Cell Biology	Vertex Pharmaceuticals, Inc.	Development of Ferret Models for CF using VX-770 & guide RNAs
Gerke, Alicia	Internal Medicine	United Therapeutics Corporation	A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung DiseaseRIN-PH-201
Hornick, Douglas	Internal Medicine	Parion Sciences	A Phase 2a, Randomized, Double-blind, Placebocontrolled,
Horwitz, Phillip	Internal Medicine	Daiichi Sankyo, Inc.	ENVISAGE TAVI-AF
Howard, Matthew	Neurosurgery	Johns Hopkins University	Targeted Neuroplasticity Training (TNT)
Huang, Chou-Long	Internal Medicine	Boehringer Ingelheim Pharmaceuticals, Inc.	Boehringer Ingelheim Pharmaceuticals Research Agreement
Krysan, Damian	Pediatrics	University of Toronto	Targeting Hsp90 in cryptococcal fungal pathogenesis
Langbehn, Douglas	Psychiatry	University College London	TREAT-HD: targeting neurodegeneration in Huntington's disease
Lee, Amy	Molecular Physiology & Biophysics	NIH	Regulation of auditory calcium channels
Milhem, Mohammed	Internal Medicine	Sarcoma Alliance for Research through Collaboration	A Phase II Randomized Controlled Trial of Neoadjuvant Pembrolizumab with Radiotherapy and Adjuvant Pembrolizumab in Patients with High-Risk, Localized Soft Tissue Sarcoma of the Extremity
Milhem, Mohammed	Internal Medicine	TRACON Pharmaceuticals, Inc.	A Randomized Phase 3 Trial of TRC105 and Pazopanib vs Pazaopanib Alone in Patients with Advanced Angiosarcoma (TAPPAS)
Milhem, Mohammed	Internal Medicine	Immunocore Limited	A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared with Investigator's Choice in HLA-A*0201 Positive Patients with Previously Untreated Advanced Uveal Melanoma
Milhem, Mohammed	Internal Medicine	Checkmate Pharmaceuticals	A Multicenter, Open Label, Phase 1B Clinical Study of CMP-001 In Combination With Pembrolizumab In Subjects Who Have Been Treated With Pembrolizumab For Advanced Melanoma.
Milhem, Mohammed	Internal Medicine	Polynoma LLC	A Multicenter, Double-blind, Placebo-controlled, Adaptive Phase 3 Trial of POL-103A Polyvalent Melanoma Vaccine in Post-resection Melanoma Patients with a High Risk of Recurrence Protocol: 103A-301
Miller, Delwyn	Psychiatry	Alkermes, Inc.	A Phase 3 Study to assess the Long Term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831 in Subjects with Schizophrenia, Schizophreniform Disorder, or Bipolar Disorder
Nuangchamnong, Nina	Obstetrics & Gynecology	Washington University	Reproductive Scientist Development Program (RSDP)
O'Donnell, Michael	Molecular Physiology & Biophysics	SynderBio, Inc.	STTR: Improved detection of bladder cancer recurrence using a biophysical biomarker
Ohl, Michael	Internal Medicine	US Department of Veterans Affairs	Contract Services to support Rural Health Resource Center
Otero, Jesse	Orthopaedics and Rehabilitation	OrthoCarolina Research Institute	Surgical Treatment of Chronic Periprosthetic Joint Infection
Polyak, Steven	Internal Medicine	Gilead Sciences, Inc.	A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Crohn's Disease
Polyak, Steven	Internal Medicine	AbbVie, Inc.	A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Polyak, Steven	Internal Medicine	Gilead Sciences, Inc.	A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Testicular Safety of Filgotinib in Adult Males with Moderately to Severely Active Ulcerative Colitis
Schmidt, Warren	Internal Medicine	Gilead Sciences, Inc.	A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (NASH)
Schmidt, Warren	Internal Medicine	Gilead Sciences, Inc.	A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis
Schmidt, Warren	Internal Medicine	Allergan Sales, LLC	STELLARIS: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis
Sharafuddin, Melhem	Surgery	Medtronic Vascular, Inc.	IN.PACT AV Access Study
Storm, Douglas	Urology	Allergan, Inc.	191622-120; BOTOX in the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity in Patients 5 to 17 Years of Age
Tansey, Michael	Pediatrics	Jaeb Center for Health Research Foundation, Inc.	A Study to Assess Continuous Glucose Sensor Profiles in Healthy Non-Diabetic Subjects
Taylor, Eric	Biochemistry	Cirius Therapeutics, Inc.	Cirius Therapeutics, Inc.
Vigil Gonzales, Carlos	Internal Medicine	Syros Pharmaceuticals	A Biomarker-directed Phase 2 Trial of SY-1425 a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Voigt, Michael	Internal Medicine	Cirius Therapeutics, Inc.	A Phase 2, Randomized, Double-Blind, Placebo-Controlled, 12-Month, Multiple-Dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC 0602K  in Patients with NASH (EMMINENCETM)
Wilson, Mary	Internal Medicine	Banaras Hindu University	Visceral Leishmaniasis in Bihar State, India
Young, Samuel	Anatomy & Cell Biology	West Virginia University Research Corporation	Development of the Calyx of Held
Zhan, Fenghuang	Internal Medicine	Leukemia & Lymphoma Society	CLINICAL INVESTIGATION OF CD38+/LIGHT CHAIN +/CD24+ AS STEM CELL MARKERS IN MYELOMA

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SEPTEMBER 2017

PI	Department	Sponsor	Title
Abou Alaiwa, Mahmoud	Internal Medicine	University of Texas Health Science Center at Tyler	Porcine Model of Nontuberculous Mycobacterial Lung Disease
Abushahin, Laith	Cancer Center	PPD Development, LP	NIH/NCI/NCTN/PPD High Performing Site Initiative
Ahern, Christopher	Molecular Physiology & Biophysics	NIH	Photochemical determination of sodium channel voltage-dependent gating and composition
Assouline-Dayan, Yehudith	Internal Medicine	Seres Therapeutics, Inc.	A Phase 2 Multicenter, RandomizeEd, Double-Blind, Placebo-COntrolled, Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium difficile Infection (CDI) in Adults Who Have Received.
Bollier, Matthew	Orthopaedics and Rehabilitation	CONMED Corporation	University of Iowa Sports Medicine Fellowship
Bollier, Matthew	Orthopaedics and Rehabilitation	Arthrex, Inc.	Arthrex Sports Medicine Fellowship
Cadaret, Linda	Internal Medicine	Bayer Healthcare AG	PARSIFAL
Davis, Benjamin	Internal Medicine	Aimmune Therapeutics	REAL-WORLD AR101 MARKET-SUPPORTING EXPERIENCE STUDY IN PEANUT-ALLERGIC CHILDREN AGES 4 TO 17 YEARS (RAMSES)
Espinosa, Madelyn	Pathology	NIH	Targeting inflammation and immune response in HNSCC therapy
Furqan, Muhammad	Internal Medicine	Big Ten Cancer Research Consortium	A Phase II Trial of Chemotherapy plus Pembrolizumab in Patients with Advanced NSCLC Previously Treated with PD-1 or PD-L1 Inhibitor
Gerke, Alicia	Internal Medicine	United Therapeutics Corporation	An Open-Label Extension study of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung Disease
Giudici, Michael	Internal Medicine	Cardionomic, Inc.	Cardionomic Inc
Giudici, Michael	Internal Medicine	Boston Scientific Corporation	Strategic Management to Optimize Response To Cardiac Resynchronization Therapy SMART CRT
Henry, Michael	Molecular Physiology & Biophysics	SynderBio, Inc.	SBIR: Improved preparation of cell suspensions for single cell genomics
Hodgson-Zingman, Denice	Internal Medicine	Biosense Webster, Inc.	Biosense Webster EP Fellowship Grant 2017-18 academic year
Huang, Chou-Long	Internal Medicine	NIH	Regulation of renal sodium and potassium transport by WNK kinases
Klein, Jonathan	Pediatrics	Mallinckrodt Pharmaceuticals	Multicenter,Prospectively Defined Observational Registry With Retrospective Data Collection,Evaluating Premature & Term-Near Term Neonates With Pulmonary Hypertension Receiving Inhaled Nitric Oxide via Invasive or Non invasive Ventilator Support at US Cen
Leira, Enrique Pieper, Andrew Rahmatalla, Salam Schnell, Thomas	Neurology	NIH	Assessment of the effects of emergent helicopter transport on stroke in a rodent model
Luo, Yi	Urology	NIH	Inhibition of TLR4 for Treatment of Cystitis Pain
Magnotta, Vincent Wemmie, John	Radiology	NIH	Cerebellar Metabolism, Neural Circuits, and Symptoms in Bipolar Disorder
Miller, Delwyn	Psychiatry	Janssen Research and Development, LLC	A Phase 2b/3 Randomized, Double-blind, Placebo-Controlled, Parallel Group, Multicenter Study Investigation the Efficacy and Safety of JNJ-54861911 in Subjects who are Asymptomatic at Risk for Developing Alzheimer's Dementia
Narayanan, Nandakumar	Neurology	NIH	Mid-frontal delta/theta rhythms and cognitive control in Parkinson's Disease
Perepu, Usha	Internal Medicine	Academic and Community Cancer Research United	ACCRU-SC-1601:  A Phase III, Randomized, Double-Blind Study Evaluating the Safety of Two Doses of Apixaban for Secondary Prevention of Cancer Related Venous Thrombosis in Subjects who have Completed at Least Six Months of Anticoagulation Therapy.
Samaniego, Edgar	Neurology	Medicure, Inc.	Determination of the Safety of Tirofiban in the Treatment of Ruptured and Unruptured Aneurysms
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	Bristol Myers Squibb
Schmidt, Warren	Internal Medicine	US Department of Veterans Affairs	Neoplastic Interactions of hepatitis C virus with telomerase
Sharafuddin, Melhem	Surgery	Bolton Medical, Inc.	A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with Traumatic Injury of the Descending Thoracic Aorta
Sharathkumar, Anjali	Pediatrics	Baxalta Innovations GMBH	POST-MARKETING non-interventional safety evaluation of obizur in the treatment of bleeding episodes for patients with acquired hemophilia A
Sheldon, Ryan	Biochemistry	NIH	Regulation of Hepatic Lipogenesis by a Mitochondrial Pyruvate Carrier-Citrate Carrier Axis
Snyder, Peter	Internal Medicine	US Department of Veterans Affairs	Epithelial Sodium Channel Trafficking
Starner, Timothy	Pediatrics	Vertex Pharmaceuticals, Inc.	A Phase 2, Randomized, Double-blind, Controlled Study to Evaluate the Safety and Efficacy of VX-659 Combination Therapy in Subjects Aged 18 Years and Older With Cystic Fibrosis
Vaughan Sarrazin, Mary	Internal Medicine	NIH	Dosing of Direct Oral Anticoagulants for stroke prevention in Atrial Fibrillation:  Patterns, Consequences, and Guidance
Wilken, Jason	Physical Therapy	Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.	The BADER Consortium: Maximizing Out Patient Rehabilitation Effectiveness (MORE)
Winokur, Patricia	Internal Medicine	Brigham and Women's Hospital	Influenza Vaccine - INVESTED study
Young, Samuel	Anatomy & Cell Biology	Michael J. Fox Foundation for Parkinson's Research	Production of HdAd typed 5 LRRK2 expression vectors
Zakharia, Yousef	Internal Medicine	AstraZeneca AB	A Phase III, Open Label, Randomized, Controlled, Multi-Center Study to Assess the Efficacy and Safety of Savolitinib vs Sunitinib in Patients with MET-Driven, Unresectable and Locally Advanced, or Metastatic Papillary Renal Cell Carcinoma (PRCC)

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AUGUST 2017

PI	Department	Sponsor	Title
Ahrens, Richard	Pediatrics	Vertex Pharmaceuticals, Inc.	Phase 3b, Randomized, Double-blind, Placebocontrolled, Parallel Group Study to Assess the Safety, Efficacy, and Tolerability of Tezacaftor/Ivacaftor (TEZ/IVA) in an Orkambiexperienced Population Who Are Homozygous forthe F508del-CFTR Mutation
Brenner, Charles	Biochemistry	ChromaDex, Inc.	Maternal and Neonatal Effects of NR
Coleman, Mitchell	Orthopaedics and Rehabilitation	National Institutes of Health	Do Changes in Thiol Metabolism Mediate Osteoarthritis Progression?
Dayal, Sanjana	Internal Medicine	National Institutes of Health	Peroxide mediated prothrombotic effects of aging
Durgempudi Tripura, Sundara	Anesthesia	B. Braun Medical Inc.	Beta Implementation OR PathTrac at the University of Iowa Hospitals & Clinics
Ebach, Dawn	Pediatrics	University of North Carolina at Chapel Hill	Anti-TNF Monotherapyversus Combination Therapy with Lose Dose Methotrexate in Pediatric Crohn's disease (COMBINE)
Faraci, Frank	Internal Medicine	US Department of Veterans Affairs	Role of PPAR-gamma in cerebral endothelium
Furqan, Muhammad	Internal Medicine	Big Ten Cancer Research Consortium	A Phase Ib/II Study of Anti-PD-1 Antibody Pembrolizumab and Imprime PGG for Patients with Metastatic Non-Small Cell Lung Cancer After Progression on First-Line Chemotherapy:   Big Ten Cancer Research Consortium BTCRC-LUN15-017
Gerke, Alicia	Internal Medicine	US Food & Drug Administration	Defining the natural history of sarcoidosis in a retrospective cohort to inform design of clinical trials
Grumbach, Isabella	Internal Medicine	US Department of Veterans Affairs	CaMKII as a regulator of diabetic retinopathy
Hasan, David	Neurosurgery	Advanced Endovascular Therapeutics	Evaluation of a Nanometer-Scale Hemocompatible and Antithrombotic Coating Technology for Commercially Available Intracranial Stents and Flow Diverters
Hinton, Antentor	Internal Medicine	Burroughs Wellcome Fund	Mechanisms for Insulin-dependent regulation of skeletal muscle mitochondria by OPA1
Hodgson-Zingman, Denice	Internal Medicine	Medtronic, Inc.	EP Fellowship Grant
Jabbari, Ali	Dermatology	National Institutes of Health	Defining T helper cell associated cytokines and mechanisms in Alopecia Areata
Kang, Sinyoung Brennan, Timothy	Anesthesia	National Institutes of Health	TRPA1 in Postoperative Pain
Karandikar, Nitin	Pathology	Iowa City Veterans Affairs Medical Center	Immunotherapeutic Regulatory CD8 T cells in Autoimmune Demyelinating Disease
Mathews, Katherine	Pediatrics	PTC Therapeutics, Inc.	An Open-Label, Safety Study for Previously Treated Ataluren (PTC124) Patients with Nonsense Mutation Dystrophinopathy
Milhem, Mohammed	Internal Medicine	Amgen, Inc.	A Phase 1b/2, Multicenter, Open-label Trial to Evaluate the Safety and Efficacy of Talimogene Laherparepvec and Ipilimumab Compared to Ipilimumab Alone in Subjects With Previously Untreated, Unresectable, Stage IIIb-IV Melanoma No.20110264
Milhem, Mohammed	Internal Medicine	Celgene Corporation	A Phase I, Open-Label, Multicenter, Randomized, 2-Period, Crossover Study to Evaluate the Bioquivalence and Food Effect Bioavailability of CC-486 (Oral Azacitidine) Tablets in Adult Cancer Subjects
Nuangchamnong, Nina	Obstetrics & Gynecology	Washington University	Reproductive Scientist Development Program (RSDP)
Oral, Resmiye	Pediatrics	Iowa Department of Human Services	Trauma Informed Systems of Care in Iowa
Perlman, Stanley	Microbiology	National Institutes of Health	PPG: SARS-CoV-Host Cell Interactions and Vaccine Development
Philibert, Robert	Psychiatry	University of Georgia	Psychosocial Context and the Biological Clock: Changes in Weathering during Middle-Age
Polyak, Steven	Internal Medicine	Gilead Sciences, Inc.	A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Testicular Safety of Filgotinib in Adult Males with Moderately to Severely Active Ulcerative Colitis
Randak, Christoph	Pediatrics	National Institutes of Health	Probing adenylate kinase-dependent CFTR gating in vivo and as therapuetic target
Russell, Stephen	Ophthalmology & Visual Sciences	ProQR Therapeutics B.V.	ORA-ProQR QR-110 LCA clinical trial
Sabharwal, Rasnapreet	Internal Medicine	American Heart Association	Ang-(1-7) protects against stress-induced cardiac morbidity and mortality in muscular dystrophy
Santillan, Mark	Obstetrics & Gynecology	Washington University	RSDP Supplement Grant
Schultz, Michael	Radiology	ViewPoint Molecular Targeting, LLC	Production of Image-Guided Metastatic Melanoma Therapy Radiopharmaceuticals
Seo, Seongjin	Ophthalmology & Visual Sciences	National Institutes of Health	Retrograde intraflagellar transport in photoreceptors
Sharathkumar, Anjali Lentz, Steven Macfarlane, Donald	Pediatrics	University of Texas Health Science Center at Houston	Regional Hemophilia Network Competing Continuation
Shy, Michael	Neurology	Acceleron Pharma, Inc.	A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ACE-083 in Patients with Charcot-Marie-Tooth Disease Types 1 and X
Spies, M. Ashley	Biochemistry	National Institutes of Health	Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase
Stapleton, Jack Houtman, Jon	Internal Medicine	National Institutes of Health	The role of HCV RNA-targeted phosphatase PTPRE in T cell activation
Starner, Timothy	Pediatrics	Anthera Pharmaceuticals, Inc.	A Phase 3, Randomized, Open-Label, Assessor-Blind, Non-Inferiority, Active-Comparator Study Evaluating the Efficacy and Safety of Liprotamase in Subjects with Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency
Starner, Timothy	Pediatrics	Novartis Pharmaceuticals Corporation	A prospective observational study in cystic fibrosis patients with chronic respiratory Pseudomonas aeruginosa infection treated with TOBI PodhalerTM (tobramycin inhalation powder) or other FDA approved inhaled antipseudomonal antibacterial drugs
Stuart, Scott	Psychiatry	National Institutes of Health	Pragmatic Strategies for Assessing and Enhancing High Fidelity Delivery of Interpersonal Psychotherapy (IPT) in Community Practice
Thomas, Christie	Internal Medicine	Shire ViroPharma, Inc.	A randomized double-blind placebo-controlled study to evaluate the efficacy and safety of Cinryze (C1 esterase inhibitor [human]) for the treatment of acute antibody-mediated rejection in kidney transplant patients
Van Heukelom, Paul	Emergency Medicine	Cepheid	Nasal Swab and Nasopharyngeal Swab Specimen Collection for use with Xpert Xpress Flu and/ or Flu/ RSV Assays
Vaughan Sarrazin, Mary	Internal Medicine	US Department of Veterans Affairs	Contract Services to support Rural Health Resource Center
Vaughan Sarrazin, Mary	Internal Medicine	US Department of Veterans Affairs	Contract Services to support VISN 23 PACT Demo Lab
Vigil Gonzales, Carlos	Internal Medicine	Seattle Genetics, Inc.	A randomized, double-blind, placebo-controlled phase 2 study of vadastuximab talirine (SGN-CD33A) in combination with cytarabine and daunorubicin (7+3) induction chemotherapy in newly-diagnosed acute myeloid leukemia patients.
Wahls, Terry	Internal Medicine	US Department of Veterans Affairs	Center for the Prevention and Treatment of Visual Loss
Weiner, George	Cancer Center	National Institutes of Health	Lymphoma Specialized Program of Research Excellence (SPORE) in Human Cancer
Welsh, Michael	Internal Medicine	University of California, San Francisco	Pre Clinical and Clinical Development of a Novel Thiol-Saccharide Mucolytic
Wibbenmeyer, Lucy	Surgery	American Burn Association	Acute Burn ResUscitation Multicenter Prospective Observational Trial (ABRUPT)
Wilken, Jason	Physical Therapy	Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.	Improved Training Program for Fall Prevention of Warfighters with Lower Extremity Trauma (RAPID REHAB)
Zakharia, Yousef	Internal Medicine	X4 Pharmaceuticals, Inc.	A Phase 1/2 Trial of X4P-001 as Single Agent and in Combination with Axitinib in Patients with Advanced Renal Cell Carcinoma
Zhang, Jian	Pathology	American Heart Association	Regulation of Autoimmune Myocarditis by Protein Ubiquitination

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JULY 2017

PI	Department	Sponsor	Proposal Title
Adams, Christopher	Internal Medicine	National Institutes of Health	Molecular pathogenesis of skeletal muscle atrophy
Ahern, Christopher	Molecular Physiology & Biophysics	Emily's Entourage	Therapeutic Correction of CFTR Nonsense Mutations
Anderson, Michael	Molecular Physiology & Biophysics	National Institutes of Health	Genetic dissection of pigmentary glaucoma
Attanasio, Massimo	Internal Medicine	National Institutes of Health	Role of GLIS2 in the Development of Cystic Kidney Disease
Bassuk, Alexander	Pediatrics	National Institutes of Health	Mechanistic studies on regenerative medicine approaches to childhood blindness
Bell, Edward	Pediatrics	Children's Hospital of Philadelphia	Post natal Growth and Retinopathy of Prematurity (G-ROP) Studies
Boes, Aaron	Pediatrics	Hugo W. Moser Research Institute at Kennedy Krieger, Inc.	Investigating the Neural Basis of Posterior Fossa Syndrome
Bonthius, Daniel	Pediatrics	National Institutes of Health	NO-mediated neuroprotection against alcohol:  mechanism and potential therapy
Chimenti, Ruth	Physical Therapy	National Institutes of Health	Mechanism-based treatment approach to chronic tendinopathy pain
Comellas, Alejandro	Internal Medicine	Janssen Research and Development, LLC	A Study to Explore the Incidence of Influenza and RSV in Adults Hospitalized with Acute
Cui, Huxing	Pharmacology	National Institutes of Health	Behavioral characterization of humanized mouse model of eating disorder
Dixon, Bradley	Internal Medicine	PPD Investigator Services, LLC	Anemia Studies in CKD: Erythropoiesis via Novel PHI Daprodustat-in Incident Dialysis (ASCEND-ID)
Elcock, Adrian	Biochemistry	National Institutes of Health	Molecular Simulations of the Cell
Fingert, John	Ophthalmology & Visual Sciences	National Institutes of Health	TBK1-Related Glaucoma
Fingert, John Mullins, Robert	Ophthalmology & Visual Sciences	National Institutes of Health	Molecular Genetics of Normal Tension Glaucoma
Flynn, Ryan	Radiation Oncology	Infondrian LLC	An Automated Patient Chart Error Detection System for Radiation Therapy
Furqan, Muhammad	Internal Medicine	Novartis Pharmaceuticals Corporation	A phase II, multicenter, three-cohort study of oral cMET inhibitor INC280 in adult patients with EGFR wild-type (wt), advanced non-small cell lung cancer (NSCLC) who have received one or two prior lines of systemic therapy for advanced/metastatic disease
Grumbach, Isabella	Internal Medicine	US Department of Veterans Affairs	Effect that CaMKII inhibition in vascular smooth muscle cells has on blood pressure
Imai, Yumi	Internal Medicine	National Institutes of Health	Role of lipid droplet protein in obesity and diabetes
Jennissen, Charles	Emergency Medicine	Iowa Department of Transportation	Increasing Public Awaremenss about the Dangers of Riding Off-Road Vehicles on the Road
Lee, Sangil	Emergency Medicine	Vanderbilt University	Guided-HF
Legge, Kevin	Pathology	National Institutes of Health	Chronic Alcohol Alteration of Influenza-Specific CD8 T cell Immunity and Protection
Levy, Barcey	Family Medicine	National Institutes of Health	Comparative Effectiveness of Fecal Immunochemical Tests with Optical Colonoscopy
Macfarlane, Donald	Internal Medicine	KaryopharmTherapeutics, Inc.	Phase 2b, Open-Label, Single-Arm Study of Selinexor Plus Low-Dose Dexamethasone in Patients with Multiple Myeloma Previously Treated with Lenalidomide, Pomalidomide, Bortezomib, Carfilzomib, and an anti-CD38 Monoclonal Antibody (mAb) and Refractory to Pri
Magnotta, Vincent Wemmie, John	Radiology	National Institutes of Health	Characterization and Enhancement of Functional T1rho Imaging
Meier, Jeffery	Internal Medicine	Sanofi Pasteur, Inc.	Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection
Milhem, Mohammed	Internal Medicine	Oncolys BioPharma, Inc.	Open-label, Multi-center Phase IIa Study to Evaluate the Efficacy, Safety, and Immunological Response of OBP 301, Telomerase Specific Replication-competent Oncolytic Adenovirus in Patients with Unresectable Metastatic Melanoma
Miller, Delwyn	Psychiatry	Vanguard Research Group	A Study to Evaluate the Effect of ALKS 3831 Compared to Olanzapine on Body Weight in Young Adults with Schizophrenia, Schizophreniform, or Bipolar Disorder Who are Early in their Illness
Monga, Varun	Internal Medicine	Orbus Therapeutics, Inc.	A Phase 3, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress / Recur After Irradiation and Adjuvant Temozolomide Chemotherapy (
Monga, Varun	Internal Medicine	Rising Tide Foundation for Clinical Cancer Research	Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b/2 trial
Nopoulos, Peggy	Psychiatry	National Institutes of Health	Longitudinal Assessment of Brain Structure and Function in Myotonic Dystrophy
Ohl, Michael	Internal Medicine	US Department of Veterans Affairs	Contract Services to support Rural Health Resource Center
Price, David	Biochemistry	George Washington University	A family of compounds that reactivate latent HIV without T cell activation
Rhodes, Troy	Internal Medicine	Boston Scientific Corporation	APPRAISE ATP
Richerson, George	Neurology	National Institutes of Health	Carver College of Medicine Clinical Neuroscientist Training Program (CNS-TP)
Richerson, George	Neurology	National Institutes of Health	Diversity Supplement, Parent grant, SUDEP Research Alliance: Respiratory and Arousal Mechanisms
Sharafuddin, Melhem	Surgery	Bolton Medical, Inc.	A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro in Subjects with an Acute, Complicated Type B Aortic Dissection
Sheffield, Val	Pediatrics	National Institutes of Health	Complex Mechanisms in Bardet-Biedl Syndrome Retinopathy
Sheffield, Val	Pediatrics	National Institutes of Health	Novel Glaucoma Treatment Using Genome Editing
Sinn, Patrick	Pediatrics	National Institutes of Health	A Hybrid Viral/Nonviral Vector for CFTR Delivery to CF Pig Airways
Sivitz, William	Internal Medicine	Case Western Reserve University	Epidemiology of Diabetes Interventions and Complications (EDIC)
Sohn, Elliott	Ophthalmology & Visual Sciences	National Institutes of Health	Choroidal Disease Mechanisms in AMD
Stone, Edwin	Ophthalmology & Visual Sciences	Dove Foundation	William J. Kimberling, Ph.D., Usher Research Laboratory
Stone, Edwin	Ophthalmology & Visual Sciences	National Philanthropic Trust	Glaucoma Excellence Fund
Tsalikian, Eva	Pediatrics	University of South Florida	Safety and Efficacy of Imatinib for Preseerving Beta-Cell Function in New Onset Type 1 Diabetes Mellitus
Varga, Steven	Microbiology	National Institutes of Health	Balancing protection versus immunopathology by RSV-specific memory CD8 T cells
Weiner, George	Cancer Center	National Institutes of Health	Cancer Center Support Grant (CCSG)
Winokur, Patricia	Internal Medicine	National Institutes of Health	VTEU FY2018, Task A, Option 1
Winokur, Patricia	Internal Medicine	National Institutes of Health	14-0107 Yellow Fever Vaccine - Task C - Option 3
Winokur, Patricia	Internal Medicine	National Institutes of Health	VTEU Task Area A-D FY2017 - Option 2A Supplement
Wu, Jing	Pharmacology	American Heart Association	The Role of Endothelial Cullin3 in Vascular Function and Blood Pressure Regulation

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JUNE 2017

PI	Department	Sponsor	Proposal Title
Ahmed, Azeemuddin	Emergency Medicine	Iowa Department of Public Health	Emergency Medical Services Medical Director Recruitment
Bollier, Matthew	Orthopaedics and Rehabilitation	Smith & Nephew Orthopaedics	Univ. of Iowa Orthopedic Sports Medicine Fellowship
Boudreau, Ryan	Internal Medicine	Roy J. Carver Charitable Trust	Systematic characterization of post-transcriptional gene regulatory networks in cardiac disease
Brown, Kyle	Internal Medicine	TARGET PharmaSolutions	A 5-year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepatitis
Buatti, John	Radiation Oncology	Galera Therapeutics, LLC	A phase 1, open-label, multi-center, dose escalation study of the safety, tolerability, pharmacodynamic and pharmacokinetic properties of intravenous GC4419 in combination with radiation and chemotherapy for squamous cell cancers of the head and neck
Buchanan, Gordon	Neurology	National Institutes of Health	Sleep state-dependent mechanisms of seizure-induced death
Coryell, William	Psychiatry	Janssen Research and Development, LLC	An Open-label, Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression
Davies, Brandon	Biochemistry	Wayne State University	An investigation of Angptl8's function, mechanism and therapeutic potential
Dhanesha, Nirav	Internal Medicine	American Heart Association	Mechanistic Role of Integrin 91 in Modulation of Arterial Thrombosis
Grumbach, Isabella	Internal Medicine	American Heart Association	CaMKII in mitochondria drives smooth muscle migration and neointimal hyperplasia
Hoffman, Eric	Radiology	Columbia University	Subclinical interstitial lung disease in MESA and FAR-ILD
Howard, Matthew	Neurosurgery	Johns Hopkins University	Targeted Neuroplasticity Training (TNT)
Ince, Mirac	Internal Medicine	US Department of Veterans Affairs	Determining which elements of the TH2 signaling pathway in BMT recipients are critical for intestinal immune conditioning
Jesudoss, Randhir	Internal Medicine	TARGET PharmaSolutions	A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis
Karandikar, Nitin	Pathology	Iowa City Veterans Affairs Medical Center	Immunotherapeutic Regulatory CD8 T Cells in Autoimmune Demyelinating Disease
Keith, Jerrod	Surgery	Allergan, Inc.	Breast Implant Follow-up Study: A Long-term Observational Study of the Safety of Allergan Silicone Gel-filled Breast Implants as Compared Both to Saline-filled Breast Implants and to National Norms
Kreder, Karl	Urology	National Institutes of Health	Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
Kuehn, Markus	Ophthalmology & Visual Sciences	Boehringer Ingelheim Pharmaceuticals, Inc.	BI-Iowa Study: Neurotrophic factors in diabetic retinopathy
Kuehn, Markus	Ophthalmology & Visual Sciences	Glaucoma Research Foundation	GRF Shaffer Grant - A New Look at the Role of Microglia in Glaucoma
Langbehn, Douglas	Psychiatry	University College London	Improving function in huntington's disease through neurofeedback
Legge, Kevin Waldschmidt, Thomas	Pathology	National Institutes of Health	Nanovaccine-Mediated Immune Protection Against Influenza Virus
Liu, Jing	Internal Medicine	American Heart Association	MicroRNA-204 in Aortic Aneurysmal Disease
London, Barry	Internal Medicine	Columbia University	Mitigation of Radiation Induced Damage to the Cardiac Conduction System by Mitochondrial Superoxide
Mathews, Katherine	Pediatrics	Italfarmaco S.p.A.	Randomised, double blind, placebo controlled, multicentre study to evaluate the efficacy and safety of givinostat in ambulant patients with Duchenne Muscular Dystrophy.
Mathews, Katherine	Pediatrics	Bristol-Myers Squibb Medical Imaging, Inc.	A Randomized, Double-Blind, Placebo-Controlled, Study to Assess the Efficacy, Safety, And Tolerability of BMS-986089 in Ambulatory Boys with Duchenne Muscular Dystrophy
Mathews, Katherine	Pediatrics	Pfizer, Inc.	A Multicenter, Open-Label Extension Study to Evaluate the Long Term Safety of PF-06252616 in Boys with Duchenne Muscular Dystrophy
Mazur, Alexander	Internal Medicine	BIOTRONIK	Plexa Regsitry
Meier, Jeffery	Internal Medicine	Chimerix, Inc.	The Chimerix CMX001 Registry A Prospective Observational Study for the Long-term Follow-up of Subjects Previously Enrolled in Selected Clinical Studies of CMX001
Milhem, Mohammed	Internal Medicine	Checkmate Pharmaceuticals	A Multicenter, Open Label, Phase 1B Clinical Study of CMP-001 In Combination With Pembrolizumab In Subjects Who Have Been Treated With Pembrolizumab For Advanced Melanoma.
Miller, Benjamin	Orthopaedics and Rehabilitation	Orthopaedic Research & Education Foundation	Improving Multi-institutional Collaboration by Creating a Sarcoma Registry
Moye-Rowley, William	Molecular Physiology & Biophysics	University of Tennessee Health Science Center	Upc2A: A Central Regulator and Achilles' Heel of Fluconazole Resistance in Candida glabrata
Nopoulos, Peggy Wemmie, John	Psychiatry	National Institutes of Health	The Iowa Neuroscience Specialty Program in Research Education (INSPIRE)
Parekh, Kalpaj	Cardiothoracic Surgery	University of Southern California	IPSC Stem Cell CFFT
Paulsen, Jane	Psychiatry	National Institutes of Health	Statistical disease modeling and clinimetrics to prepare for preventive trials in huntington disease
Perschbacher, Katherine	Pharmacology	American Heart Association, Midwest Affiliate	Molecular Mechanisms of RGS2 in Preeclampsia
Roller, Richard	Microbiology	National Institutes of Health	Regulation of budding during herpesvirus nuclear egress
Russo, Andrew	Molecular Physiology & Biophysics	US Department of Veterans Affairs	Photosensitivity as a preclinical assessment for treatment of post-traumatic headache
Sah, Rajan	Internal Medicine	American Heart Association	Ion channel regulation of pancreatic beta cell function
Sato, Mariko	Pediatrics	Children's Hospital of Philadelphia	COG: APEC14B1 Project Everychild
Segaloff, Deborah	Molecular Physiology & Biophysics	National Institutes of Health	A Mouse Model to Demonstrate the Impact of Myometrial FSHR on Fertility
Sharafuddin, Melhem	Surgery	Bolton Medical, Inc.	A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the Relay PRO Thoracic Stent-Graft in Subjects with Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers
Sheffield, Val	Pediatrics	Roy J. Carver Charitable Trust	The Science Behind Curing Heritable Blindness Research Programs of Excellence
Sheffield, Val	Pediatrics	Roy J. Carver Charitable Trust	Automated Retinal Differentiation Lab Instrumentation
Stevens, Hanna	Psychiatry	Roy J. Carver Charitable Trust	Neuropsychiatry Research Junior Research Programs of Excellence
Stone, Edwin	Ophthalmology & Visual Sciences	Usher 1F Collaborative, Inc.
Stone, Edwin	Ophthalmology & Visual Sciences	Roy J. Carver Charitable Trust	The Science Behind Curing Heritable Blindness Research Programs of Excellence
Strack, Stefan	Pharmacology	Roy J. Carver Charitable Trust	Mitochondrial Dynamics and Calcium Cycling in Neuronal Injury, Excitably and Plasticity Research Program of Excellence
Sunderland, John	Radiology	University of California, San Francisco	Qualification and Harmonization of PET/MRI for Cancer Clinical Trials
Tanaka, Tomohiro	Internal Medicine	TARGET PharmaSolutions	A 5-year Longitudinal Observational Study of the Natural History and Management of Patients with Hepatocellular Carcinoma
Tomasson, Michael	Internal Medicine	Washington University	Center for Multiple Myeloma Nanotherapy, Project 3
Tranel, Daniel	Neurology	California Institute of Technology	The Neurobiology of Social Decision-Making:  Social Inference and Context
Tsalikian, Eva	Pediatrics	OPKO Biologics Ltd	A phase 3, open-label, randomized, multicenter, 12 months, efficacy and safety study of weekly MOD-4023 compared to daily Genotropin - therapy in pre-pubertal children with growth hormone deficiency.
Winokur, Patricia	Internal Medicine	National Institutes of Health	15-0064 A/H5N8 Vaccine

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MAY 2017

PI	Department	Sponsor	Proposal Title
Abel, E. Dale Norris, Andrew	Internal Medicine	National Institutes of Health	Diabetes Research Training Program
Abel, Edwin	Molecular Physiology & Biophysics	Washington State University	Non-Neuronal Regulators of Sleep
Ahrens, Richard	Pediatrics	Quintiles, Inc.	A Multi-center, Randomized, Placebo-Controlled, Ascending Dose Phase I Study Designed to Assess the Safety, Tolerability, and Pharmacokinetics of PTI-428 in Subjects with Cystic Fibrosis
Allen, Bryan	Radiation Oncology	University of Texas Southwestern Medical Center	The STABLE-MATES Trial
Benson, Christopher	Internal Medicine	US Department of Veterans Affairs	Role of ASICs within sensory neurons in health and disease
Bishop, Gail	Microbiology	US Department of Veterans Affairs	VA IPA
Choi, Kent	Surgery	Atox Bio Ltd.	ATB-202: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Study Of AB103 As Compared To Placebo In Patients With Necrotizing Soft Tissue Infections (NSTI)
Comellas, Alejandro	Internal Medicine	Pearl Therapeutics, Inc.	A Randomized, Double-Blind, Parallel Group, Multi-Center Study to Assess the Efficacy and Safety of PT009 compared to PT005 on COPD Exacerbations over a 52-Week Treatment Period in Subjects With Moderate to Very Severe COPD
Cornell, Robert	Anatomy & Cell Biology	Marin Community Foundation	Preliminary analysis of zebrafish mutants with defects in embryonic development
Derdeyn, Colin	Radiology	Pulse Therapeutics, Inc.	Rapid Magnetomotive Thrombolysis for Stroke
Diekema, Daniel	Pathology	bioMerieux, Inc.	ADDENDUM to VITEK 2 and VITEK 2 Compact GP19 Antimicrobial Susceptibility Tests
Engelhardt, John	Anatomy & Cell Biology	Vertex Pharmaceuticals, Inc.	Vertex Pharmaceuticals  / Agreement 2 / Amendment 3
Femino, John	Orthopaedics and Rehabilitation	OMeGA Medical Grants Association	OMeGA Medical Grants Association Foot/Ankle Fellowship 2017-2018
Fischer, Anthony	Pediatrics	National Institutes of Health	Initial Attachment of Bacteria to Mucus Strands in Cystic Fibrosis
Gantz, Bruce	Otolaryngology - Head & Neck Surgery	Iowa City Veterans Affairs Research Foundation
Giangrande, Paloma	Internal Medicine	University of Missouri-Columbia	Database and software development for protein-nucleic acid structure prediction
Gildenberg, Melissa	Biochemistry	National Institutes of Health	Investigation of Rad5 Structure and Function in Error-Free Template Switching
Grose, Charles	Pediatrics	Iowa City Veterans Affairs Medical Center	Immunohistochemical Analysis for Herpes Zoster
Habelhah, Hasem	Pathology	National Institutes of Health	HtrA2-mediated RIP1 cleavage regulates neuronal inflammation and death
Horwitz, Phillip	Internal Medicine	St. Jude Medical, Inc.	Interventional Cardiology Fellowship Grant 2017-18 academic year
Janz, Siegfried	Pathology	University of California, Los Angeles	Regulation of c-myc translation by hnRNP A1: Role in multiple myeloma tumor responses
Kamholz, John	Neurology	Vaccinex, Inc.	A Phase 2, multi-center, randomized, double-blind, placebo controlled study in subjects with late prodromal and early manifest Huntington disease (HD) to assess the safety, tolerability, pharmacokinetics, and efficacy of VX15/2503
Kamholz, John	Neurology	Huntington's Disease Society of America	HDSA Centers of Excellence
Karwal, Mark	Internal Medicine	Merck Sharp & Dohme Company	A Phase III Study of Pembrolizumab vs Best Supportive Care as Second-Line Therapy in Subjects with Previously Systemically Treated Advanced Hepatocellular Carcinoma (KEYNOTE 240).
Karwal, Mark	Internal Medicine	NSABP Foundation, Inc.	NSABP PROTOCOL B-57-I/PALLAS
Kline, Joel	Internal Medicine	GlaxoSmithKline LLC	Post-authorisation Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events in COPD Patients Using Inhaled UMEC/VI Combination or Inhaled UMEC versus Tiotropium (Study 2
Krasowski, Matthew	Pathology	Roche Diagnostics Corporation	Performance Evaluation of Elecsys Anti-HBe Immunoassay and PreciControl Anti-HBe on cobas e 602 Analyzer
Leone, Jose	Internal Medicine	Merck Sharp & Dohme Company	A Phase III, Randomized, Double-blind Study to Evaluate Pembrolizumab Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy for Triple Negative Breast Cancer
Mathews, Katherine	Pediatrics	Muscular Dystrophy Association	MDA Care Center
Mathews, Katherine	Pediatrics	Santhera Pharmaceuticals (Switzerland) Ltd	A Phase III Double Blind , Randomized, Placebo-controlled study assessing the efficacy, safety and tolerability of idebenone in pati ents with Duchenne Muscular Dsytrophy receiving Glucocorticoid Steriods.  SIDEROS
Mazur, Alexander	Internal Medicine	University of Rochester	JAVA CRT
Michaelson, Jacob	Psychiatry	Simons Foundation	SPARK recruitment center in Iowa
Miller, Delwyn	Psychiatry	University of Southern California	Long-Term Nicotine Treatment of Mild Cognitive Impairment
Moore, Steven	Pathology	Sarepta Therapeutics	SOW 7 - New Statement of Work
Narayanan, Nandakumar	Neurology	Roy J. Carver Charitable Trust	Neuromodulation Research Program of Excellence
Santillan, Donna Santillan, Mark Grobe, Justin	Obstetrics & Gynecology	Carmentix Pte Ltd.	Estimating copeptin in urine during the first trimester of pregnancy
Seering, Melinda	Anesthesia	General Electric Healthcare	Multi-site Anesthesia randomized controlled STudy of End tidal control (Et Control) compared to conventional anesthesia Results (MASTER-Anesthesia Trial)
Sharathkumar, Anjali	Pediatrics	Johns Hopkins University	Prospective Multi-Center Evaluation of the Duration of Therapy for Thrombosis in Children (the Kids-DOTT Trial)
Snyder, Peter	Internal Medicine	US Department of Veterans Affairs	Epithelial Sodium Channel Trafficking
Stapleton, Jack	Internal Medicine	Iowa Department of Public Health	HIV Core Medical and Support Services
Stevens, Hanna	Psychiatry	Nellie Ball Trust	Early Neurodevelopmental Mechanisms in Schizophrenia
Stoltz, David Welsh, Michael	Internal Medicine	University of Washington, Seattle	Combined Effects of Ivacaftor and Antibiotics Study - Ancillary Stuies
Stoltz, David Zabner, Joseph	Internal Medicine	National Institutes of Health	Airway Alkalinization and Repurposing Tromethamine as a Therapeutic Approach in Cystic Fibrosis
Strack, Stefan	Pharmacology	National Institutes of Health	Predoctoral Training in the Pharmacological Sciences
Strack, Stefan	Pharmacology	National Institutes of Health	PP2A in Neurodevelopmental Disorders
Strathearn, Lane	Pediatrics	National Institutes of Health	Oxytocin and Brain Reward and Stress Responses to Infant Cues in Addicted Mothers
Tarini, Beth	Pediatrics	Genetic Alliance	NBS Clearinghouse- Genetics Alliance
Tsalikian, Eva	Pediatrics	Ascendis Pharma A/S	A multicenter, Phase 3, randomized, open-label, active-controlled, parallel-group trial investigating the safety, tolerability, and efficacy of TransCon hGH administered once a week versus standard daily hGH replacement therapy over 52 weeks in prepuberta
Uc, Aliye	Pediatrics	University of Texas, MD Anderson Cancer Center	Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer
Vaughan Sarrazin, Mary	Internal Medicine	US Department of Veterans Affairs	Contract Services to support Rural Health Resource Center
Wessel, Jan	Neurology	Roy J. Carver Charitable Trust	Neuropsychiatric Diseases Junior Research Programs of Excellence
Winokur, Patricia	Internal Medicine	National Institutes of Health	VTEU Task Area A-D FY2017
Young, Samuel	Anatomy & Cell Biology	National Institutes of Health	Regulation of Synaptic Vesicle Dynamics in the Auditory System

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