Includes new, competitive renewal and supplemental awards.
2019: January, February, March, April, May, June, July
2018: January, February, March, April, May, June, July, August, September, October, November, December
2017: May, June, July, August, September, October, November, December
JULY 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abel, Edwin G | Molecular Physiology & Biophysics | US Department of Health & Human Services, National Institutes of Health | Mechanistic studies on the impact of sleep deprivation on gene regulation |
| Bishop, Gail A | Microbiology | US Department of Defense, Congressionally Directed Medical Research Program | CA180190P1 CD24 Tumor-Initiating Cell as a Novel Therapeutic Target in Myeloma |
| Boes, Aaron Daniel | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Investigating the Effects of Transcranial Magnetic Stimulation with Intracranial EEG in Humans |
| Brenner, Charles Michael | Biochemistry | ChromaDex, Inc. | Evaluating the Oral Bioavailability of NAD Boosters in the Brain |
| Brenner, Charles Michael | Biochemistry | Bill & Melinda Gates Foundation | Testing NAD Precursors as Galactagogues |
| Cornell, Robert A | Anatomy & Cell Biology | Massachusetts General Hospital | Genomic and Functional Analysis of IRF6 Target Genes in Orofacial Cleft Pathogenesis |
| Furqan, Muhammad | Internal Medicine | AstraZeneca Pharmaceuticals LP | A Phase IB, Open-Label, Multi-Center Study to Determine the Efficacy and Safety of Durvalumab in Combination With Novel Oncology Therapies, With or Without Chemotherapy, for First-Line Stage IV Non-Small Cell Lung Cancer (NSCLC) (MAGELLAN) |
| Gutmann, Laurie | Neurology | Expansion Therapeutics, Inc. | Double-Blind, Placebo-Controlled, Dose-Range-Finding, Crossover Trial of Single Day Administration of ERX-963 in Adults with Myotonic Dystrophy Type 1 |
| Hoffman, Eric Alfred | Radiology | Washington University in St. Louis | Washington University's Precision Biologic Interventions for Severe Exacerbation Prone Asthma (PrecISE) |
| Infield, Daniel | Molecular Physiology and Biophysics | National Institutes of Health | Chemical Biology of CFTR Regulation |
| Leira, Enrique | Neurology | National Institutes of Health | The University of Iowa Stroke Preclinical Assessment Center for Neuroprotection in Stroke |
| Lentz, Steven | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Program in Hematology: Molecular & Cell Biology Blood Cells |
| Link, Brian Krall | Internal Medicine | AstraZeneca Pharmaceuticals LP | Treatment Patterns, Outcomes, and Patient-Reported Health-Related Quality of Life: A Prospective Disease Registry of Patients with Mantle Cell Lymphoma Treated with Novel Agents |
| Mathews, Katherine Dianne | Pediatrics | Sarepta Therapeutics | Long-term, Open-label Extension Study for Patients with Duchenne Muscular Dystrophy Enrolled in Clinical Trials Evaluating Casimersen or Golodirsen |
| Nizar, Jonathan | Internal Medicine | National Institutes of Health | Contribution of Renal Tubule Insulin Receptor on Proximal Tubule Sodium Transport and Hypertension in the Metabolic Syndrome |
| Smith, Richard J | Otolaryngology - Head & Neck Surgery | US Department of Health & Human Services, National Institutes of Health | Autosomal Dominant Non-Syndromic Hearing Loss - Its Genetic Diagnosis and Treatment |
| Stoltz, David A | Internal Medicine | Cystic Fibrosis Foundation | Iowa Cystic Fibrosis Foundation Research & Development Program |
| Vigil Gonzales, Carlos Enrique | Internal Medicine | Aprea Therapeutics | A Phase III Multicenter, Randomized, Open Label Study of APR-246 in Combination with Azacitidine vs Azacitidine Alone for the Treatment of TP53 Mutant Myelodysplastic Syndromes |
| Willock, Amy | Microbiology | Department of Defense, CDMRP | Regulation of the B cell receptor and B cell homeostasis by tumor necrosis factor receptor associated factor 3 |
| Young, Samuel Matthew | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Development of Helper Dependent Adenoviral Vectors for Inner Ear Gene Therapy Approaches |
| Zakharia, Yousef | Internal Medicine | Exelixis, Inc. | Cabozantinib and Pembrolizumab as a Front Line Therapy for Advanced Melanoma |
| Zhan, Fenghuang | Internal Medicine | US Department of Defense, Congressionally Directed Medical Research Program | CA180190 CD24 Tumor-Initiating Cell as a Novel Therapeutic Target in Myeloma |
JUNE 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Ahern, Christopher A | Molecular Physiology & Biophysics | US Department of Health & Human Services, National Institutes of Health | Chemical Biology of Voltage-Gated Cation Channels |
| Ahrens, Richard C | Pediatrics | Aurobindo Pharma USA, Inc. | Master Service Agreement and SOW #1 |
| Allen, Lee-Ann Harty, John |
Microbiology | US Department of Health & Human Services, National Institutes of Health | Interdisciplinary Immunology Postdoctoral Training Program |
| Andersen, Allan Michael | Psychiatry | Behavioral Diagnostics, LLC | An integrated epigenetic ELISA saliva kit for detecting & quantifying both tobacco and nicotine use |
| Avner, Benjamin S | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Human neutrophil derived microvesicles modulate phagocyte activity |
| Bailin, Steven | Internal Medicine | Boston Scientific Corporation | INTERRUPT AF |
| Bollier, Matthew John | Orthopaedics and Rehabilitation | Smith & Nephew, Inc. | Univ. of Iowa Sports Medicine Fellowship |
| Chimenti, Ruth | Physical Therapy | US Department of Health & Human Services, National Institutes of Health | Mechanism-based treatment approach to chronic tendinopathy pain |
| Cho, Josalyn Leah Olsen | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Tim3 is a novel regulator of dendritic cell-T cell interactions in influenza |
| Derdeyn, Colin P | Radiology | Pulse Therapeutics, Inc. | Magnetically Enhanced Diffusion for Intra-Arterial (MEDIA) Treatment of Acute Ischemic Stroke |
| Doddapattar, Prakash | Internal Medicine | American Heart Association | Mechanistic role of integrin alpha9beta1 in atherosclerosis |
| Dunn-Johnson, Camille C | Otolaryngology - Head & Neck Surgery | MED-EL Corporation | Iowa Cochlear Implant Clinical Research Center Study of SSD using MED-EL Cochlear Implants |
| Eisenberg, Joshua Mark | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course - Trauma Basic Principles |
| Ford, Bradley | Pathology | JMI Laboratories | ANALYTICAL VALIDATION OF CLINICAL MICROBIOLOGY PROCEDURES |
| Fredericks, Douglas Christian | Orthopaedics and Rehabilitation | Globus Medical, Inc. | Assessment of Umbilical Cord Derived Stem Cells in a Rabbit Degenerative Disc Model |
| Furqan, Muhammad | Internal Medicine | AbbVie, Inc. | M17-327: A Phase 1 Study of SC-011 as a Single-Agent and in Combination with ABBV-181 in Subjects with Relapsed or Refractory Small Cell Lung Cancer |
| Gakhar, Lokesh | Medicine Administration | Bonumose Biochem LLC | Crystallography project for Bonumose LLC |
| Geerling, Joel C | Neurology | Iowa Fraternal Order of the Eagles | Circuit-based treatments for hydrocephalic dementia with urinary incontinence |
| Gerke, Alicia | Internal Medicine | Biogen, Inc. | A Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of BG00011 in Patients With Idiopathic Pulmonary Fibrosis |
| Gordon, David Jon | Pediatrics | Fraternal Order of Eagles | Identification of Synergistic Drug Combinations Using a High-Throughput, Chemical-Genetic Screen |
| Grose, Charles | Pediatrics | University of Illinois at Urbana-Champaign | Role of gC Glycoprotein in transmission of avian and human herpes viruses |
| Gulbrandsen, Trevor Robert | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course - Trauma Basic Principles of Fracture Management |
| Gutmann, Laurie | Neurology | Virginia Commonwealth University | Myotonic Dystrophy Clinical Research Network (DMCRN) Multicenter Study of Natural History and Genetic Modifiers in Myotonic Dystrophy Type-1 (END-DM1) |
| Hamzeh, Nabeel Y | Internal Medicine | aTyr Pharma, Inc. | A Randomized, Double-Blind, Placebo-Controlled Multiple Ascending Dose Study of Intravenous ATYR1923 in Patients with Pulmonary Sarcoidosis |
| Kline, Joel N | Internal Medicine | inVentiv Health Clinical | A Long-term, Randomized, Double-blind, Multicenter, Parallel Group, Phase III Study Evaluating the Efficacy and Safety of PT027 Compared to PT007 Administered as Needed in Response to Symptoms in Symptomatic Adults and Children 4 Years of Age or Older wit |
| Kohler, James Gilweit | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course - Trauma Basic Principles |
| Kohlmeyer, Jordan Lynn | Pharmacology | Children's Tumor Foundation | The RABL6A-RB1 pathway in MPNST pathogenesis and therapy |
| Magalhaes-Silverman, Margarida | Internal Medicine | Kadmon Holdings, Inc. | KD025-213 A Phase 2, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of KD025 in Subjects with Chronic Graft Vs Host Disease After at Least 2 Prior Lines of Systemic Therapy (the ROCKstar Study) |
| Marcinkiewcz, Catherine Anne | Pharmacology | US Department of Health & Human Services, National Institutes of Health | The role of serotonin signaling in the nucleus accumbens in excessive alcohol drinking |
| Mathews, Katherine Dianne | Pediatrics | Santhera Pharmaceuticals (Switzerland) Ltd | A Phase III Open-Label Extension Study to Assess the Long-Term Safety and Efficacy of Idebenone (Drug) in Patients with Duchenne Muscular Dystrophy (DMD) who completed the SIDEROS study (SIDEROS-E) (Study). |
| Mathews, Katherine Dianne | Pediatrics | AveXis, Inc. | AveXis Consulting |
| Mazur, Alexander | Internal Medicine | Attune Medical | Evaluating Active Esophageal Cooling during Cardiac Ablation Procedures |
| Menda, Yusuf Schultz, Michael K |
Radiology | US Department of Health & Human Services, National Institutes of Health | Alpha-Particle Emitter Peptide Receptor Targeted Radionuclide Therapy for Neuroendocrine Tumors |
| Milhem, Mohammed Mahmoud | Internal Medicine | Merck Sharp & Dohme Company | Adjuvant Therapy with Pembrolizumab versus Placebo in Resected Highrisk Stage II Melanoma: A Randomized, Double-blind Phase 3 Study |
| Muffly, Scott | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course - Trauma Basic Principles |
| Nester, Carla Marie | Pediatrics | Novartis Pharmaceuticals Corporation | A randomized, double blinded placebo-controlled dosefinding study of efficacy, pharmacodynamics, safety and tolerability of LNP023 in patients with C3 glomerulopathy |
| Nizar, Jonathan | Internal Medicine | Iowa Fraternal Order of the Eagles | Sympathetic nerve control of kidney function in obesity-associated hypertension |
| Paradee, William Jerome | Medicine Administration | University of Alabama at Birmingham | UAB_AAV3164_AAV3297_2019 |
| Pinnaro, Catherina T | Pediatrics | Fraternal Order of Eagles | What causes diabetes in Turner Syndrome |
| Polgreen, Philip Matthew | Internal Medicine | MTF Biologics | Using Prediction Rules to Estimate Frequency of Deceased Donor Screening Criteria to Increase Tissue Availability |
| Pugely, Andrew | Orthopaedics and Rehabilitation | Lumbar Spine Research Society | A Multi-Disciplinary Approach to Reduce Chronic Opioid Use Prior to Elective Lumbar Spine Surgery |
| Rahmouni, Kamal | Pharmacology | US Department of Veterans Affairs | IPA for Deng Fu Guo |
| Rahmouni, Kamal | Pharmacology | US Department of Veterans Affairs | IPA for Donald Morgan |
| Ramchandran, Kanchna Phadke, Sneha Deepak |
Internal Medicine | Iowa Fraternal Order of the Eagles | Assessing DNA methylation associated with chemotherapy induced cognitive deficits (CICD) in early stage breast cancer in older women |
| Russell, Michael David | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course - Trauma Basic Principles of Fracture Management |
| Samaniego, Edgar A | Neurology | University of Cincinnati | StrokeNet: Multi-arm Optimization of Stroke Thrombolysis (MOST) Stroke Trial |
| Samaniego, Edgar A | Neurology | Rapid Medical Ltd | Tiger Study |
| Santillan, Mark Kharim | Obstetrics & Gynecology | University of Missouri-Columbia | RSDP Supplement Grant |
| Scroggins, Sabrina Marie | Obstetrics & Gynecology | American Heart Association | Treatment of Preeclampsia Using Cellular Immunotherapy |
| Sheffield, Val C | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Novel Genome Editing for the Treatment of Glaucoma |
| Shy, Michael E | Neurology | Alnylam Pharmaceuticals, Inc. | Alnylam Clinical Trial HELIOS-A: A Phase 3 Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with hATTR Amyloidosis |
| Singh, Minati | Internal Medicine | Iowa Fraternal Order of the Eagles | Secret niche of aging brain: Klotho unlocks |
| Sinn, Patrick Ladd | Pediatrics | Cystic Fibrosis Foundation | Transducing basal cells and ionocytes for CF phenotypic correction |
| Stapleton, Jack T | Internal Medicine | Bavarian Nordic | POX-MVA-031 Clinical Trial |
| Tansey, Michael J | Pediatrics | University of South Florida | HYDROXYCHLOROQUINE FOR PREVENTION OF ABNORMAL GLUCOSE TOLERANCE AND DIABETES IN INDIVIDUALS AT-RISK FOR TYPE 1 DIABETES MELLITUS |
| Taylor, Eric Benjamin | Biochemistry | POXEL | Determination of PXL Compound Mitochondrial Pyruvate Carrier (MPC) IC50 Values |
| Terry, William Wayne | Pediatrics | Fraternal Order of Eagles | Providing therapeutic supplies to support psycho-social therapies for AYA cancer patients |
| Usachev, Yuriy M | Pharmacology | US Department of Health & Human Services, National Institutes of Health | The Role of the Complement System in Spinal Mechanisms of Chronic Pain |
| Vigil Gonzales, Carlos Enrique | Internal Medicine | AbbVie, Inc. | M16-785: Phase 1b Study of Venetoclax and AMG 176 in Patients with Relapsed/Refractory |
| Vikram, Ajit | Internal Medicine | American Heart Association | Gut-microbiota regulated vascular miR-204 promotes diabetes-associated endothelial dysfunction |
| Yan, Ziying | Anatomy & Cell Biology | Cystic Fibrosis Foundation | Gene Editing for Cystic Fibrosis Gene Therapy in Ferret Models |
| Zakharia, Yousef | Internal Medicine | Calithera BioSciences, Inc. | CX-839-011: A Phase 1b/2 Open Label, Dose Escalation and Expansion Study of the Glutaminase Inhibitor CB-839 in Combination with the PARP Inhibitor Talazoparib in Patients with Advanced or Metastatic Solid Tumors |
| Zhang, Jun | Internal Medicine | Big Ten Cancer Research Consortium | BTCRC LUN17-139: A phase II study or Carboplatin plus Pemetrexed plus Atezolizumab plus Bevacizumab in chemotherapy and immunotherapy-naive patients with stage IV non-squamous non-small cell lung cancer |
MAY 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Aksan, Nazan Suheyla | Neurology | US Department of Health & Human Services, National Institutes of Health | Evaluating the disease-modifying potential of a sleep intervention for Alzheimer's Disease outcomes |
| Anderson, Steven Wayne | Neurology | Iowa State University | Insulin Resistance, Biomarkers of Brain Function, and Intermittent Calorie Restriction |
| Badovinac, Vladimir | Pathology | US Department of Health & Human Services, National Institutes of Health | Differentiation of pathogen-specific memory CD8 T cell responses |
| Bender, David Paul | Cancer Center | NRG Oncology Foundation, Inc. | 2019 NRG Oncology Member Institution Clinical Trial Fixed Price Subaward Agreement [Expires: 02/28/25] |
| Bernat, John Andrew | Pediatrics | Idorsia Pharmaceuticals US Inc. | A multi-center, open-label, uncontrolled, single-arm, extension study to determine |
| Bishop, Gail A | Microbiology | US Department of Veterans Affairs | IPA for Kyp Oxley |
| Bishop, Gail A | Microbiology | University of North Carolina at Chapel Hill | Function of IL35+B Cells in Pancreatic Cancer |
| Brenner, Charles Michael | Biochemistry | Cytokinetics, Inc. | Cytokinetics/NAD Service Center Agreement |
| Carvour, Martha Lydia | Internal Medicine | Mayo Clinic | Enhance arthroplasty research through electronic health records and NLP-enabled informatics |
| Ellermeier, Craig D | Microbiology | US Department of Health & Human Services, National Institutes of Health | Extra-Cytoplasmic Function Sigma Factor Senses and Responds to Beta-Lactam Stress in Gram-Positive Bacteria |
| Erickson, Bradley Allan | Urology | Urotronic, Inc. | ROBUST III Clinical Study Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease A Randomized Control Trial |
| Foster, Kristin Janine | Pediatrics | American Cancer Society | GSCNP Focusing on Emotional & Mental Health in Pediatric & AYA Cancer |
| Gantz, Bruce Jay | Otolaryngology - Head & Neck Surgery | Cochlear Americas | Impact of Intraoperative Electrocochleography (ECoG) Monitoring on Post-Operative Hearing Preservation |
| Hajewski, Christina Josephine Femino, John |
Orthopaedics and Rehabilitation | Orthopaedic Research & Education Foundation | The Utility of Deltoid Ligament Reconstruction in Syndesmotic Injuries |
| Harland, Kari Kay | Emergency Medicine | Iowa Department of Public Health | Sexual Violence Prevention Evaluation |
| Hodgson-Zingman, Denice Marie | Internal Medicine | Abbott | EP Fellowship Grant 2019-20 academic year |
| Hodgson-Zingman, Denice Marie | Internal Medicine | BIOTRONIK | Biotronik EP Fellowship Grant 2019-20 academic year |
| Hoffman, Eric Alfred Kruger, Stanley J |
Radiology | US Department of Health & Human Services, National Institutes of Health | Hyperpolarized Xe-129 MRI for Functional Lung Phenotyping |
| Horwitz, Phillip Andrew | Internal Medicine | Abbott | Interventional Cardiology Fellowship Grant 2019-20 academic year |
| Jabbari, Ali | Dermatology | Insilico Medicine, Inc. | In vivo Preclinical testing of Insilico Medicine Drug for alopecia areata |
| Kim, Yusung - | Radiation Oncology | Philips Medical Systems, Inc. | Generation of 3D Prescription-Map Plugin in Pinnacle Treatment Planning System (TPS) |
| Knudson, C Michael | Medicine Administration | Leidos Biomedical Research, Inc. aka SAIC-Frederick | Clinical Proteomics Tumor Analysis Consortium 3.0 |
| Krasowski, Matthew David | Pathology | Abbott Laboratories | Cardiac Troponin Concentrations in Healthly Transgender People |
| Lenert, Petar | Internal Medicine | Sanofi US Services Inc. | A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis (GCA) |
| Lentz, Steven | Internal Medicine | Hikari DX, Inc. | Clinical Performance Evaluation of T-TAS 01 PL Chip |
| Limoli, Dominique | Microbiology | Cystic Fibrosis Foundation | PHASE II_Modulating interspecies interactions in cystic fibrosis respiratory disease |
| London, Barry Brenner, Charlie Irani, Kaikobad |
Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Evaluating NAD Supplementation as a Novel Treatment for Arrhythmias |
| Long, Jeffrey D | Psychiatry | Vanderbilt University | Early detection of Huntington's Disease: Longitudinal analysis of basal ganglia and cortical thickness |
| Manicassamy, Balaji | Microbiology | US Department of Health & Human Services, National Institutes of Health | Modulation of Influenza Virus Replication and Fitness by Adenosine Deaminases |
| Mathews, Katherine Dianne | Pediatrics | Muscular Dystrophy Association | Muscular Dystrophy Association Neuromuscular Observational Research (MOVR) Data Hub |
| Mathews, Katherine Dianne | Pediatrics | AveXis, Inc. | A Managed Access Program (MAP) Cohort Treatment Protocol to provide AVXS-101 to |
| Mazur, Alexander | Internal Medicine | BIOTRONIK | Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy |
| Monga, Varun | Internal Medicine | Deciphera Pharmaceuticals, LLC | A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastroinitestinal Stromal Tumors after Treatment with Imatinib (Intrigue) |
| Nau, Peter Nealey | Surgery | Foundation for Surgical Fellowships | Fellowship in Bariatric Surgery |
| Panaich, Sidakpal | Internal Medicine | Cleveland Clinic Foundation | WATCH-TAVR Protocol |
| Petrucci, Alexandra | Neurology | American Epilepsy Society | AES Predoctoral Research Fellowship |
| Powers, Jennifer Gloeckner | Dermatology | Medical University of South Carolina | INCREASING ACCESS TO CLINICAL MICROBIOME SPECIMENS VIA A LIVING BIOME BANK |
| Russell, Stephen R | Ophthalmology & Visual Sciences | ProQR Therapeutics B.V. | ORA-ProQR QR-110-002 LCA Extension Study |
| Sato, Mariko | Pediatrics | Children's Hospital of Philadelphia | A Phase 2 Study of Inotuzumab Ozogamicin in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL) |
| Sharathkumar, Anjali Alatkar | Pediatrics | Hemophilia Alliance Foundation | Patient Navigation for Health Disparity Reduction |
| Smith, Mark Charles | Radiation Oncology | Elekta, Inc. | Agreement between ELEKTA and UIHC Rad Onc |
| Snyder, Peter M | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | 9th Annual International Conference of Aldosterone and ENaC |
| Suneja, Manish | Internal Medicine | Alliance for Academic Internal Medicine | AAIM Innovation Grant |
| Tsalikian, Eva | Pediatrics | Insys Development Company, Inc. | A Multicenter, Open-Label Study to Assess the Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Patients with Prader-Willi Syndrome |
| Yang, Shujie | Obstetrics & Gynecology | US Department of Health & Human Services, National Institutes of Health | Restoring Progestin Sensitivity in Endometrial Cancer |
APRIL 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Allen, Lee-Ann | Internal Medicine | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | (636D93053) -- Studies based on the discovery of neutrophil metabolic Reprogramming as a new mechanism for apoptosis inhibition |
| Alvarez, Paulino | Internal Medicine | Yale University | TRANSFORM-HF |
| Benson, Christopher J | Internal Medicine | US Department of Veterans Affairs | 36C26319C0088 (636D93054) - Role of ASICs within sensory neurons in health and disease |
| Cho, Josalyn Leah Olsen | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Airway Dendritic Cells in the Allergic Asthma Phenotype |
| Faine, Brett Anthony | Emergency Medicine | OLIVE VIEW-UCLA EDUCATION & RESEARCH INSTITUTE | EMERGEncy ID NET Study Group: Management of Diverticulitis in the Emergency Department |
| Farooq, Umar | Internal Medicine | Novartis Pharmaceuticals Corporation | Managed Access Program (MAP) to provide access to CTL019 (Novartis), for acute lymphoblastic leukemia (ALL) or large B-cell lymphoma patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for com |
| Gerke, Alicia | Internal Medicine | Mallinckrodt Pharmaceuticals | Educational Grant for Conference - A. Gerke |
| Groth, Christopher Lee | Neurology | Emory University | Dystonia Coalition |
| Gurung, Prajwal | Internal Medicine | Kemin Industries, Inc. | Experimental/Technical Services Agreement with Kemin Industries, Inc. |
| Harper, Matthew M | Ophthalmology & Visual Sciences | Iowa City Veterans Affairs Research Foundation | ICVARF 18-19 Technician MOU - Harper DOD |
| Hitchon, Patrick | Neurosurgery | InVivo Therapeutics | Randomized, Controlled, Single-blind Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care |
| Howard, Matthew A | Neurosurgery | California Institute of Technology | Neuronal Substrates of Hemodynamic Signals in the Prefrontal Cortex |
| Irani, Kaikobad | Internal Medicine | Augusta University | Gut microbiota-regulated metabolism through MicroRNA-204 |
| Johnston, Holly Anne | Radiation Oncology | Varian Medical Systems, Inc. | An automated treatment plan quality assurance tool for gynecological high dose rate brachytherapy based on failure modes and effects analysis |
| Kaczka, David Walter | Anesthesia | ZOLL Medical Corporation | David Kaczka Paid Consultation to ZOLL Q5 & Q6 |
| Kamholz, John | Neurology | Huntington's Disease Society of America | HDSA Centers of Excellence |
| Karwal, Mark William | Internal Medicine | Exact Sciences Corporation | Blood Sample Collection to Evaluate Biomarkers for Hepatocellular Carcinoma |
| Kuehn, Markus H | Ophthalmology & Visual Sciences | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Kuehn VA-PO RA support Validate passive immune transfer |
| Kuehn, Markus H | Ophthalmology & Visual Sciences | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | VA PO: Kuehn/Cheng T-Cell mediated cytotoxicity in TBI |
| Langbehn, Douglas Robert | Psychiatry | CHDI Management, Inc. | Scientific Advisory Committee |
| Lawrence, Thomas | Surgery | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Hand & Wrist Fracture Management Course |
| Lenert, Petar | Internal Medicine | Sanofi US Services Inc. | EFC15160 entitled A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with polymyalgia rheumatica (PMR) |
| Limoli, Dominique Welsh, Michael |
Microbiology | Cystic Fibrosis Foundation | Modulating interspecies interactions in cystic fibrosis respiratory disease |
| Mathews, Katherine Dianne | Pediatrics | PPD Investigator Services, LLC | A Long-term Observational Study Evaluating Eteplirsen in Patients with Duchenne Muscular Dystrophy under Conditions of Routine Clinical Practice |
| Mazur, Alexander | Internal Medicine | University of Rochester | MARVEN |
| Mullins, Robert F Tucker, Budd Albert |
Ophthalmology & Visual Sciences | US Department of Health & Human Services, National Institutes of Health | Choriocapillaris Protection and Replacement in AMD |
| Noiseux, Nicolas Olivier | Orthopaedics and Rehabilitation | Smith & Nephew, Inc. | A PROSPECTIVE, MULTI-CENTER CLINICAL STUDY EVALUATING THE LEGIONTM HINGE KNEE SYSTEM (THE LINKS STUDY) |
| Pena, Tahuanty | Internal Medicine | St. Elizabeth's Medical Center | Impact of Pre-transplant Anti-fibrotic Therapy for IPF upon Lung Transplant Outcomes |
| Perencevich, Eli N | Internal Medicine | University of Maryland | Epicenters for the Prevention of Healthcare-Associated Infections (HAIs); Cycle II Multicenter Program Studies |
| Pollard, Janet H | Radiology | Progenics Pharmaceuticals, Inc. | A Phase 3, Multi-Center, Open-Label Study to Assess the Diagnostic Performance and Clinical Impact of 18F-DCFPyL PET/CT Imaging Results in Men with Suspected Recurrence of Prostate Cancer (CONDOR) |
| Sato, Mariko | Pediatrics | Children's Hospital of Philadelphia | COG - ALTE07C1 |
| Schweizer, Marin Leigh | Internal Medicine | US Department of Health & Human Services, Agency for Healthcare Research & Quality | Povidone-iodine to Stop Access-related Infections and Transmission of Staphylococcus aureus (PAINTS) |
| Shy, Michael E | Neurology | Charcot-Marie-Tooth Association | The Inherited Neuropathy Consortium |
| Sluka, Kathleen A | Physical Therapy | US Department of Health & Human Services, National Institutes of Health | Role of macrophages in activity-induced pain and analgesia |
| Spies, Maria Malkova, Anna |
Biochemistry | US Department of Health & Human Services, National Institutes of Health | The role of human RAD52 protein in genome stability |
| Swenson, Andrea | Neurology | University of Miami | CReATe- Trial Ready Study |
| Takacs, Elizabeth Broghammer | Urology | Society of Academic Urologists | Development and Validation of a Novel Urology Residency Evaluation and Feedback System |
| Tomasson, Michael | Internal Medicine | Hoffmann-La Roche, Inc. | A Phase Ib/II Study Evaluating the Safety and Efficacy of Idasanutlin in Combination with Cytarabine and Daunorubicin in Patients Newly Diagnosed with AML and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission |
| Vigil Gonzales, Carlos Enrique | Internal Medicine | Rafael Pharmaceuticals, Inc. | AML003: Phase III Multicenter Open-Label Randomized Trial to Evaluate Efficacy and Safety of CPI-613 in Combination with High Dose Cytarabine and Mitoxantrone (CHAM) Compared to High Dose Cytarabine and Mitoxantrone (HAM) in Older Patients (>/= 60 years) |
| Wall, Michael | Ophthalmology & Visual Sciences | Dignity Health dba St. Joseph's Hospital & Medical Center | Wall - Open Up Project |
| Yadav, Ravi Prakash | Molecular Physiology & Biophysics | Knights Templar Eye Foundation, Inc. | Molecular Mechanisms of AIPL1 and its TPR domain in Leber congenital amaurosis |
| Zakharia, Yousef | Internal Medicine | Astellas Pharma Global Development, Inc. | 1951-CL-0101: A Phase 1 Study of ASP1951 in Subjects with Advanced Solid Tumors |
| Zhang, Jun | Internal Medicine | Biodesix, Inc. | Investigator Initiated Study - The role of Proteomic as a Predictor for NSCLC Immunotherapy |
| Zhao, Chen | Pathology | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Synergy of NF-kB and Notch signaling in B cell lymphomatous transformation and B cell plasticity |
MARCH 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Alvarez, Paulino | Internal Medicine | Duke University | TRANSFORM-HF |
| Awelewa, Temitope Modupe | Pediatrics | Duke University | Pediatric Trial Network: PK and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants |
| Cadaret, Linda Marie | Internal Medicine | United Therapeutics Corporation | APD811-301 |
| Carter, Calvin Stanley | Pediatrics | American Diabetes Association | Glycemic Lowering Mechanisms of Low-Frequency Electromagnetic Fields in Mouse Models of Type 2 Diabetes |
| Cornell, Robert A | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Dissecting the transcriptional network governing differentiation of periderm |
| Dowdle, Spencer | Orthopaedics and Rehabilitation | Globus Medical, Inc. | Education Grant to attend AAOS 2019 Annual Meeting |
| Fraer, Mony | Internal Medicine | Cara Therapeutics | A MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ORAL CR845 IN CHRONIC KIDNEY DISEASE PATIENTS WITH MODERATE-TO-SEVERE PRURITUS CR845-210301 |
| Gerke, Alicia | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Biomarkers for Severity, Therapy, and Disparity in Sarcoidosis: Discovery to Delivery |
| Graham, Michael | Radiology | ImaginAb, Inc. | ImaginAb Clinical Trial Agreement |
| Grose, Charles | Pediatrics | Mayo Clinic | Identification and Characterization of Children with Asthma Associated comorbidities through computational and immune phenotyping |
| Gutierrez, Santiago | Neurology | University of Texas Health Science Center at Houston | SEGA - SEdation versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke - a Randomized Comparative Effectiveness Trial. |
| Hasan, David | Neurosurgery | US Department of Health & Human Services, National Institutes of Health | 15-PGDH as a better therapeutic target than aspirin in decreasing risk of intracranial aneurysm rupture in men and women equally |
| Herwaldt, Loreen A | Internal Medicine | University of Illinois at Chicago | Epicenters for the Prevention of Healthcare-Associated Infections (HAIs); Cycle II Multicenter Program Studies |
| Huang, Chou-Long | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Klotho and Chronic Kidney Disease |
| Jackson, Jay Brooks | Medicine Administration | Wells Fargo Wealth Management | Dr. Dennis L. and Mrs. Katheryn M. Boatman Medical Scholarship Fund |
| Jackson, Jay Brooks | Medicine Administration | Wells Fargo Advisors Financial Network, LLC | Cynthia and Darrel Courtney Colon Cancer Research Fund |
| Jackson, Jay Brooks | Medicine Administration | Wells Fargo Advisors Financial Network, LLC | Cornea Transplant Research Lab Fund |
| Jackson, Jay Brooks | Medicine Administration | Seth A Bailey Courage Group, Inc. | Seth A. Bailey Sarcoma Cancer Fund- UIF Special Award |
| Jethava, Yogesh Shantilal | Internal Medicine | International Myeloma Foundation | Patients with multiple myeloma with t(11;14) translocation identified on plasma cell FISH |
| Kenny, Helena Catherine | Internal Medicine | MyoKardia, Inc. | OPA1 KO Causes Cardiac Dysfunction, ER Stress and Heart Failure |
| Larson Ode, Katie Marie Ulring | Pediatrics | Cystic Fibrosis Foundation | EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis |
| Legge, Kevin L | Pathology | Iowa State University | Universal room temperature stable influenza nanovaccine |
| Limoli, Dominique | Microbiology | Cystic Fibrosis Foundation | Modulating interspecies interactions in cystic fibrosis respiratory disease |
| Loftus, Randy Wayne | Anesthesia | Kenall Manufacturing | The Attenuation of Intraoperative S. aureus Transmission and SSIs via Use of Indigo-Clean |
| McElroy, STEVEN James | Pediatrics | Evolve BioSystems | HAWKEYE |
| Meier, Jeffery Linn | Internal Medicine | US Department of Veterans Affairs | 36C26319C0069 (636D93047) Mechanisms regulating Cytomegalovirus Research for the Iowa City VA Health Care System |
| Milhem, Mohammed Mahmoud | Internal Medicine | Checkmate Pharmaceuticals | Compassionate use CMP-001 for a single patient with uveal melanoma |
| Miller, Benjamin James | Orthopaedics and Rehabilitation | Saint Louis University | Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone: A Prospective Randomized Controlled Trial |
| Monga, Varun | Internal Medicine | NewLink Genetics Corporation | Compassionate use access to indoximod in combination with temozolomide for an adult patient with glioblastoma |
| Nance, Christopher S | Neurology | Massachusetts General Hospital | NeuroNext Clinical Trial - The TopCSPN Study / Topiramate as a Disease Modifying Therapy for CSPN |
| Newell, Elizabeth Ann | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Astrocyte-specific IL-1RI signaling effects following traumatic brain injury |
| Parekh, Kalpaj R | Surgery | US Department of Health & Human Services, National Institutes of Health | Pathogenesis of Airway Stem Cell Abnormalities on Obliterative Bronchiolitis |
| Philibert, Robert Alan | Psychiatry | University of Connecticut Health Center | Contextual and health behavior effects on epigenetic aging among African Americans |
| Polyak, Steven | Internal Medicine | AbbVie, Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study to Evaluate the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Ulcerative Colitis |
| Price, David H | Biochemistry | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Mechanisms regulating cytomegalovirus - IPA Agreement |
| Ramchandran, Kanchna | Internal Medicine | Fraternal Order of Eagles | Brain-based biomarker tools to assess cognitive deficits associated with early stage breast cancer in older women |
| Russell, Stephen R | Ophthalmology & Visual Sciences | Spark Therapeutics | SPKRPE-PASS: A Post-Authorization, Multicenter, Multinational, Longitudinal, Observational Safety Registry Study for Patients Treated with Voretigene Neparvovec |
| Russo, Andrew F | Molecular Physiology & Biophysics | US Department of Health & Human Services, National Institutes of Health | Perivascular mechanisms of CGRP-induced migraine symptoms |
| Sainju, Rup K | Neurology | Yale University | New-Onset Refractory Status Epilepticus (NORSE) Study |
| Sato, Mariko | Pediatrics | Children's Hospital of Philadelphia | COG - ALTE15N2 - St. Bladrick's Foundation |
| Shy, Michael E | Neurology | Neurogene, Inc. | March 8 & 9, 2019 Dallas CMT4J Advisory Board Consulting with Neurogene |
| Simmons, Jonathan S | Anesthesia | Entasis Therapeutics, Inc. | A Multi-center, Retrospective Study of Serious Infections Caused by Acinetobacter baumannii-calcoaceticus Complex |
| Spies, Maria | Biochemistry | US Department of Defense, Congressionally Directed Medical Research Program | Modulating Cancer Genetics for Immune Regulation and Breast Cancer Therapy |
| Spies, Maria | Biochemistry | US Department of Health & Human Services, National Institutes of Health | Assembly and Dynamics of Molecular Machines in Genome Maintenance |
| Staber, Janice Marie Rose | Pediatrics | American Thrombosis and Hemostasis Network | A Natural History Cohort Study of the Safety, Effectiveness, and Practice of Treatment for People with Hemophilia |
| Stone, Edwin M | Ophthalmology & Visual Sciences | Vanguard | William J. Kimberling, Ph.D., Usher Research Laboratory |
| Stone, Edwin M | Ophthalmology & Visual Sciences | Vanguard | William J. Kimberling, Ph.D., Usher Research Laboratory |
| Stone, Edwin M | Ophthalmology & Visual Sciences | Vanguard | William J. Kimberling, Ph.D., Usher Research Laboratory |
| Strack, Stefan | Pharmacology | Regents of the University of California Davis | Generation and characterization of mouse models of Jordan's Syndrome |
| Wattiez, Anne-Sophie | Molecular Physiology & Biophysics | US Department of Veterans Affairs | Wattiez VA Pilot - CGRP sensitization in post- traumatic headache |
| Weiner, George J | Cancer Center | Vanguard | Robert F. and Bertha M. Tribuno Bladder Cancer Research Fund |
| Weiner, George J | Cancer Center | U.S. Bank | Larry and Darlene Lehmkuhl Fund |
| Westermann, Robert | Orthopaedics and Rehabilitation | Smith & Nephew, Inc. | Arthroscopic Correction of Femoroacetabular Impingement - A joint Contact Stress Analysis |
FEBRUARY 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Assouline-Dayan, Yehudith Soubra, Mahmoud Rangarajan Murali, Arvind Tran, Huy T T |
Internal Medicine | Regeneron Pharmaceuticals, Inc. | A PHASE 3, RANDOMIZED, 3-PART STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF DUPILUMAB IN ADULT AND ADOLESCENT PATIENTS WITH EOSINOPHILIC ESOPHAGITIS |
| Bender, David Paul | Obstetrics & Gynecology | Big Ten Cancer Research Consortium | Big Ten Consortium-GYN15-013 |
| Cadaret, Linda Marie | Internal Medicine | Bayer AG | VITALITY |
| Chatterjee, Snehajyoti | Molecular Physiology & Biophysics | Nellie Ball Trust | Investigating the role of the schizophrenia-associated gene Nr4A2 in the regulation of gene expression using a novel tavi-tag approach and single-neuronal nuclear RNA |
| Day, Molly Owens, Jessell |
Orthopaedics and Rehabilitation | Journal of Bone and Joint Surgery | JBJS Orthopedic Resident Journal Club |
| Farooq, Umar | Internal Medicine | Big Ten Cancer Research Consortium | Phase I Study of Nivolumab in Combination with Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma |
| Ford, Bradley | Pathology | Accelerate Diagnostics, Inc. | Improving Outcomes and Antibiotic Stewardship for Patients with Bacteremia (IOAS): Accelerate PhenoTestTM BC Kit Registry Study |
| Gaine, Marie E | Molecular Physiology & Biophysics | Nellie Ball Trust | A longitudinal study of DNA methylation patterns in schizophrenia |
| Griguer, Corinne E Oliva, Claudia |
Radiation Research Laboratory | US Department of Health & Human Services, National Institutes of Health | Paracrine Signaling in Glioma: Bioenergetics Heterogeneity and Chemoresistance |
| Gutierrez, Santiago | Neurology | Society of Vascular and Interventional Neurology | Development of a Novel Risk Stratification Score for Patients Presenting with Acute Cerebral Venous Sinus Thrombosis |
| Hall, Mederic Micah Chimenti, Ruth |
Orthopaedics and Rehabilitation | American Medical Society for Sports Medicine Foundation | Efficacy and Safety of Ultrasound Guided Tenotomy |
| Hansen, Marlan Rex | Otolaryngology - Head & Neck Surgery | Massachusetts Eye and Ear Infirmary | Prospective, randomized, placebo-controlled phase 2 trial of aspirin for vestibular schwannoma |
| Hasan, David | Neurosurgery | Medtronic, Inc. | 2019 University of Iowa Cerebrovascular Research Update Symposium |
| Herwaldt, Loreen A Schweizer, Marin Leigh |
Internal Medicine | PDI Healthcare | Feasibility of Povidone Iodine Decolonization among Orthopedic Trauma Surgery Patients |
| Law, Ian Harry | Pediatrics | Medtronic, Inc. | ATrial TAchycardia PAcing Therapy in Congenital Heart |
| Leslie, Kimberly Kay Samuelson, Megan I Gonzalez Bosquet, Jesus Devor, Eric Thiel, Kristina Wyatt Salem, Aliasger Karimjee Au, Kin Fai |
Obstetrics & Gynecology | US Department of Health & Human Services, National Institutes of Health | Targeted Therapy for Endometrial Cancer |
| Link, Brian Krall | Internal Medicine | University of Rochester | A phase III double blind, prospective randomized trial to evaluate the supplemental effect of vitamin D (cholecalciferol) on progression-free survival in patients with low tumor-burden indolent non-Hodgkin lymphoma treated with rituximab therapy (ILyAD - |
| Manicassamy, Balaji | Microbiology | US Department of Health & Human Services, National Institutes of Health | ENDOTHELIAL CELL TROPISM IN THE PATHOGENESIS AND HOST RESPONSE AGAINST INFLUENZA VIRUSES - RESUBMISSION 01 |
| McGowan, Stephen E | Internal Medicine | US Department of Veterans Affairs | VA IPA for Diann McCoy |
| McLendon, Jared Milligan | Internal Medicine | American Heart Association | Regulation of Cardiac Signaling by Beta-Taxilin |
| Milhem, Mohammed Mahmoud | Internal Medicine | Forma Therapeutics, Inc. | A Phase 1b/2 Study of FT-2102 in Patients with Advanced Solid Tumors and Gliomas with an IDH1 Mutation |
| Milhem, Mohammed Mahmoud | Internal Medicine | Exicure, Inc. | AST-008-102: A Phase 1b/2 Study of AST-008 Combined with Pembrolizumab in Patients with Advanced Solid Tumors |
| Milhem, Mohammed Mahmoud | Internal Medicine | Nektar Therapeutics | 17-262-01: A Phase 1/2, Open-label, Multicenter, Dose Escalation and Dose Expansion Study of NKTR-262 in Combination with NKTR-214 and in Combination with NKTR-214 plus Nivolumab in Patients with Locally Advanced or Metastatic Solid Tumor Malignancies (P |
| Minard, Annabel Yurie | Molecular Physiology & Biophysics | American Diabetes Association | Role of novel Rab10 interactors in Glut4 translocation |
| Mohr, Nicholas Matthew Ward, Marcia M Chrischilles, Elizabeth A Parker, Edith A |
Emergency Medicine | US Department of Health & Human Services, Agency for Healthcare Research & Quality | Evaluating the Role of Telemedicine in Improving Rural Emergency Department Sepsis Care |
| Nopoulos, Peggy Colleen Conrad, Amy Lynn Magnotta, Vincent Alfonso |
Psychiatry | Boston Children's Hospital | Immunologic and Neurodevelopmental Consequences of Neonatal Anemia and Thrombocytopenia and their Treatments |
| Noureddine, Lama | Internal Medicine | Sanofi-Aventis U.S. Inc. | Multicenter, randomized, double-blind, placebo-controlled two stage study to characterize the efficacy, safety, tolerability and pharmacokinetics of GZ/SAR402671 in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPK |
| O'Donnell, Michael A | Internal Medicine | Medical Enterprises Europe B.V. | A Multicenter, Single-Arm Study Evaluating the Efficacy of Synergo Radiofrequency-Induced Thermochemotherapy Effect (RITE) with Mitomycin C (Synergo RITE + MMC) in CIS Non-Muscle Invasive Bladder Cancer (NMIBC) Bacillus Calmette-Guerin (BCG)-Unresponsiv |
| Pearlman, Amy Marcia | Urology | Boston Scientific Corporation | University of Iowa Men's Health Program 2018-2019 Monthly Seminar Line-Up |
| Polyak, Steven Elliott, David E Cooper, Elizabeth Ann Pederson, Megan Marie |
Internal Medicine | University of North Carolina at Chapel Hill | Tofacitinib response in UC (TOUR) - a real world prospective multicenter study |
| Santillan, Mark Kharim Pierce, Gary L |
Obstetrics & Gynecology | University of Pittsburgh | Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia |
| Sato, Mariko | Pediatrics | Children's Hospital of Philadelphia | COG - ANBL1531, Jubilant Draximage Inc. |
| Sato, Takashi Shawn Peter Bansal, Manish |
Radiology | Bracco Diagnostics, Inc. | A Prospective Multicenter Observational Study to Evaluate Thyroid Function of Pediatric Subjects from Birth to 3 Years Exposed to Isovue (IOP-120) |
| Sharathkumar, Anjali Alatkar | Pediatrics | American Thrombosis and Hemostasis Network | A Multicenter Study of Eradication of Hepatitis C Virus (HCV) Infection in People with Hemophilia and Bleeding Disorders (ATHN 6: HCV Eradication Study) |
| Sharathkumar, Anjali Alatkar | Pediatrics | Pfizer, Inc. | A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF GMI-1070 RIVIPANSEL (GMI-1070) IN THE TREATMENT OF VASO-OCCLUSIVE CRISIS IN HOSPITALIZED SUBJECTS WITH SICKLE CELL DISEASE |
| Shibli-Rahhal, Amal Ali Choi, James Yuknam |
Medicine Administration | Arnold P. Gold Foundation | Arnold P. Gold Foundation Leonard Tow Humanism in Medicine Award |
| Shy, Michael E | Neurology | Muscular Dystrophy Association | The Inherited Neuropathy Consortium |
| Song, Long-Sheng | Internal Medicine | US Department of Veterans Affairs | 36C26319C0051 (636D93038) Oxidative Stress, PKC Signaling and Heart Failure |
| Weeks, Kristin | Surgery | Telligen Community Initiative | Scaling the Healthcare Delivery Science and Management Distinction Track |
| Williams, Aislinn Joanmarie | Psychiatry | Nellie Ball Trust | Investigating cerebellar abnormalities in schizophrenia using patient-derived stem cells |
JANUARY 2019
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Bathla, Girish | Radiology | Siemens Medical Solutions USA, Inc. | Neuro Software Evaluation CT |
| Berg, Daniel J | Cancer Center | NSABP Foundation, Inc. | NSABP Protocol C-13.1 |
| Bernat, John Andrew | Pediatrics | Protalix Biotherapeutics | Open Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegunigalsidase Alfa (PRX-102) 2 mg/kg Administered by Intravenous Infusion Every 4 Weeks in Patients with Fabry Disease |
| Boudreau, Ryan Lee | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Regulation and role of the cardiac sodium channel Nav1.5 in heart failure |
| Dai, Dao-Fu | Pathology | US Department of Health & Human Services, National Institutes of Health | The role of energy sensor signaling in mitochondrial cardiomyopathy |
| Day, Molly | Orthopaedics and Rehabilitation | Mid-America Orthopaedic Association | Mid-America Orthopaedic Association Education Grant |
| Dhanesha, Nirav Anilkumar | Internal Medicine | American Society of Hematology | Novel mechanisms for arterial and venous thrombosis |
| Engelhardt, John F | Anatomy & Cell Biology | Talee Bio, Inc. | SOW #1 |
| Erickson, Bradley Allan | Urology | Boston Scientific Corporation | 2019-2020 Urology Fellowship |
| Exil, Vernat | Pediatrics | American Heart Association | Gestational exposure to eCIGS and susceptibility to allergic asthma and bronchopulmonary dysplasis |
| Falls, Kelly Christine | Radiation Research Laboratory | US Department of Health & Human Services, National Institutes of Health | Targeting lung and breast cancer cell oxidative metabolism with D-penicillamine and disulfiram |
| Farooq, Umar | Internal Medicine | Big Ten Cancer Research Consortium | Phase I/II Study of Ixazomib and Romidepsin in Relapsed/ Refractory Peripheral T-cell Lymphoma (PTCL) |
| Fingert, John Harrison Anderson, Michael Gary |
Ophthalmology & Visual Sciences | US Department of Health & Human Services, National Institutes of Health | CRISPR/Cas9 approaches to model exfoliation syndrome |
| Fraer, Mony | Internal Medicine | Arbor Research Collaborative for Health | CKDOPPS |
| Fredericks, Douglas Christian | Orthopaedics and Rehabilitation | Prosidyan, Inc. | Statement of Work No. One |
| Gantz, Bruce Jay | Otolaryngology - Head & Neck Surgery | Cochlear Americas | Nucleus Hybrid L24 Implant System New Enrollment Post Approval Study |
| Garje, Rohan | Internal Medicine | Endocyte, Inc. | PSMA-617-01: An International, Prospective, Open-Label, Multicenter, Randomized Phase 3 Study of 177Lu-PSMA-617 in the Treatment of Patients with Progressive PSMA-Positive Metastatic Castration-Resistant Prostate Cancer |
| Graves, Stephen Andrew | Radiology | MIM Software Inc. | MIM Beta Software Evaluation NDA |
| Griguer, Corinne E | Radiation Research Laboratory | US Department of Health & Human Services, National Institutes of Health | Cytochrome C Oxidase: Biomarker In Newly Diagnosed Glioblastoma Multiforme |
| Gutmann, Laurie | Neurology | argenx BVBA | CTA- Inc Research, LLC, Protocol # ARGX-113-1704 |
| Hadlandsmyth, Katherine E | Anesthesia | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain |
| Hendrickson, Nathan R | Orthopaedics and Rehabilitation | Mid-America Orthopaedic Association | Mid-America Orthopaedic Association Education Grant |
| Hodgson-Zingman, Denice Marie | Internal Medicine | Cardiac Pacemakers, Inc. dba Boston Scientific CRM | PREcision Event Monitoring of PatienTs with Heart Failure using HeartLogic |
| Hodgson-Zingman, Denice Marie | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | A New Pacing Approach for Cardioprotection and Repair in Heart Failure |
| Howe, James Robinson | Surgery | Children's Hospital of Philadelphia | CHOP Collaborative Research Agreement |
| Imai, Yumi | Internal Medicine | American Diabetes Association | Regulation of insulin secretion by lipid droplet proteins! |
| Irani, Kaikobad | Internal Medicine | US Department of Veterans Affairs | 36C26319C0052 (636D93040) SIRTUIN1-mediated inhibition of P66shc lysine acetylation as a novel treatment for diabetic vasculopathy |
| Kaczka, David Walter | Anesthesia | ZOLL Medical Corporation | David Kaczka Paid Consultation to ZOLL Q4 |
| Kardon, Randy Herbert | Ophthalmology & Visual Sciences | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | VA-PO: Kardon/Gramlich The impact of electrical activity and stem cell derived factors |
| McGowan, Stephen E | Internal Medicine | US Department of Veterans Affairs | 36C26319C0058 (636D93036) Contract for Diann McCoy |
| Mohr, Nicholas Matthew | Emergency Medicine | Iowa Department of Public Health | The Iowa Department of Public Health Trauma System Verification Physician Team member Agreement |
| Ochoa Nunez, Luis Alberto | Pediatrics | AltaThera Pharmaceuticals LLC | (Retrospective) Intravenous Sotalol in Pediatric and Congenital Patients: A Multi-center Registry |
| Pezzulo, Alejandro Antonio | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Heat-shock protein 90 modulates goblet cell metaplasia in human airway epithelia |
| Reisinger, Heather Schacht | Internal Medicine | US Department of Veterans Affairs | 36C26319C0045 (636D93024) Building an Optimal health and hygiene Bundle: A mixed-Methods Approach (CRE 12-289) |
| Santillan, Mark Kharim | Obstetrics & Gynecology | US Department of Health & Human Services, National Institutes of Health | Vasopressin and Preeclampsia: Early Mechanisms for Prevention |
| Schweizer, Marin Leigh | Internal Medicine | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Chronic Antibiotic Suppression after Prosthetic Joint Infection: A Target for De-Implementation |
| Sharafuddin, Melhem J | Surgery | W. L. Gore & Associates | Gore AAA 13-03 Study |
| Solimeo, Samantha Leigh | Internal Medicine | US Department of Veterans Affairs | 36C26319C0031(636D93033) Identifying Barriers to Implementation and Spread of Specialty Care Telehealth PACT Serving Rural Veterans |
| Spies, Maria | Biochemistry | Iowa State University | Analyzing paleo-enzymology data of homologous genetic recombination |
| Stapleton, Jack T | Internal Medicine | Janssen Vaccines & Prevention B.V. | A Randomized, Double-blind, Placebo-controlled First-in-Human, Phase 1/2a Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Monovalent HPV16 and HPV18 Ad26-vectored Vaccine Components and an MVA-vectored HVP 16/18 Vaccine Component in Oth |
| Swenson, Andrea | Neurology | Worldwide Clinical Trials, Inc. | A Phase III, Randomised, Placebo-Controlled Trial of Arimoclomol in Amyotrophic Lateral Sclerosis |
| Tansey, Michael J | Pediatrics | Amgen, Inc. | Double-blind, Randomized, Multicenter, Placebo-Controlled, Parallel Group Study to Characterize the Efficacy, Safety, and Tolerability of 24 Weeks of Evolocumab for Low Density Lipoprotein-Cholesterol (LDL-C) Reduction, as Add-On to Diet and Lipid-Loweri |
| Taylor, Eric Benjamin | Biochemistry | Cirius Therapeutics, Inc. | Cirius Therapeutics |
| Tsalikian, Eva | Pediatrics | Ascendis Pharma A/S | enliGHten: A Multicenter, Phase 3, Long-term, Open-label Trial Investigating Safety and Efficacy of TransCon hGH Administered Once-Weekly in Children with Growth Hormone Deficiency (GHD) Who Have Completed a Prior TransCon hGH Clinical Trial |
| Tsalikian, Eva | Pediatrics | EMMES Corporation | A double-blind, randomised, placebo-controlled, parallel group |
| Tsalikian, Eva | Pediatrics | Insys Development Company, Inc. | A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Efficacy, Safety, and Tolerability of Cannabidiol Oral Solution for the Treatment of Patients with Prader-Willi Syndrome |
| Tucker, Budd Albert Mullins, Robert F |
Ophthalmology & Visual Sciences | US Department of Health & Human Services, National Institutes of Health | Molecular Basis of Complement Defense in Choroidal Endothelial Cells |
| Weiner, George J | Cancer Center | American Cancer Society | American Cancer Society - IRG |
| Wilson, Mary E | Internal Medicine | US Department of Veterans Affairs | 36C26319C0050 (636D93037) The Role of Exosomes in the Pathogenesis of Leishmaniasis |
| Wolf, Brian Robert | Orthopaedics and Rehabilitation | University of Kentucky | MOON Shoulder Instability 6 year follow up |
| Zakharia, Yousef | Internal Medicine | Pfizer, Inc. | A Therapeutic Trial for Safety and Preliminary Efficacy of the Combination of Axitinib and Selenium in the Chemical Composition of Selenomethionine (SLM) for adult patients with advanced metastatic clear cell renal cell carcinoma (CCRCC) |
| Zakharia, Yousef | Internal Medicine | Eisai, Inc. | (IIS) Proof of concept for lenvatinib and everolimus prior to cytoreductive nephrectomy in eligible patients with locally advanced an metastatic renal cell carcinoma (RCC) |
| Zhao, Chen | Pathology | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Synergy of NF-kB and Notch signaling in B cell lymphomatous transformation and B cell plasticity |
| Zhu, Eliot | Anatomy & Cell Biology | Melanoma Research Foundation | Identification of Src family kinases that drive resistance to mutant BRAF inhibition |
DECEMBER 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abel, Edwin G | Molecular Physiology & Biophysics | University of Pennsylvania | Neural mechanisms underlying sleep disturbances in autism spectrum disorder |
| Abel, Edwin G | Molecular Physiology & Biophysics | Yale University | Translating Drug Discovery in Zebrafish and Mouse Models of ASD Risk Genes |
| Ahrens, Richard C | Pediatrics | Proteostasis Therapeutics, Inc. | A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PTI-808 in Healthy Adult Subjects and in Adults with Cystic Fibrosis |
| Bernat, John Andrew | Pediatrics | Protalix Biotherapeutics | Extension: A Randomized, Double blind, Active Control Study of the Safety and Efficacy of PRX-102 compared to Agalsidase Beta on Renal Function in Patients with Fabry Disease Previously Treated With Agalsidase Beta |
| Cadaret, Linda Marie | Internal Medicine | Lung Biotechnology Inc. | BEAT Extension |
| Chauhan, Anil | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Novel therpeautic interventions to treat ischemic stroke |
| Chitneni, Shobha | Internal Medicine | Alliance Foundation Trials, LLC | AFT-39: Electronic patient reporting of symptoms during outpatient cancer treatment: A U.S. national randomized controlled trial (the PRO-TECT trial) |
| Choi, Kent Choung | Surgery | Atox Bio Ltd. | Phase 2 randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of Reltecimod as compared to placebo in addition to standard of care in patients with sepsis-associated acute kidney injury (SA-AKI) |
| Ciliberto, Michael Anthony | Pediatrics | Marinus Pharmaceuticals, Inc. | : A Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone Treatment in Children and Young Adults with Cyclin-dependent Kinase-like 5 (CDKL5) Deficiency Disorder (CDD) Followed by Long-term Open-label Treatment |
| Davis, James Muse | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Fungal and Host Factors in Initiation of Cryptococcal Persistence |
| Derdeyn, Colin P | Radiology | University of Cincinnati | NeuroEndovascular Advisory Committee Chair, Imaging Core Trial Liaison |
| Diekema, Daniel James | Internal Medicine | Johns Hopkins University | Clostridium difficile Over Testing (C-DOT) Improvement initiative; a Multi-Prevention Epicenter Collaborative Project |
| Drack, Arlene V | Ophthalmology & Visual Sciences | Foundation Fighting Blindness | BBS10 project-Canadian FFB |
| Harty, John | Microbiology | US Department of Health & Human Services, National Institutes of Health | T resident memory in the lung |
| Hoffman, Eric Alfred | Radiology | OscillaVent, Inc. | Device for Multi-Frequency Oscillatory Ventilation in Adult Patients with the Acute Respiratory Distress Syndrome |
| Karam, Matthew David Anderson, Donald D |
Orthopaedics and Rehabilitation | Orthopaedic Trauma Association | Introducing Wire Navigation Simulation to the OTA Resident Fracture Courses |
| Kenny, Helena Catherine | Internal Medicine | American Heart Association | Inducible Deletion of OPA1 Causes Mitochondrial Fragmentation, ER stress and Cardiac Dysfunction |
| Kumar, Rahul | Internal Medicine | American Heart Association | Memory deficits and sensorimotor impairment in hyperhomocysteinemic mice before and after stroke |
| Laux, Douglas Earl | Internal Medicine | Immunicum AB | A randomized, open-label, multicenter, phase 1b/2 trial evaluating the safety and efficacy of intratumorally-administered ilixadencel in combination with checkpoint inhibitor (CPI) in advanced cancer subjects who are candidates for CPI therapy |
| Long, Jeffrey D | Psychiatry | Massachusetts General Hospital | Disease-Modifying Genes in Huntington's Disease |
| Luo, Yi | Urology | NanoMedTrix LLC | Ultrasound-based diagnostic and monitoring of bladder cancer treatment with drug released from nanoparticles |
| Mathews, Katherine Dianne | Pediatrics | Sarepta Therapeutics | Sarepta Global Advisory Board Meeting |
| Mathews, Katherine Dianne | Pediatrics | Catabasis Pharmaceuticals | A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, GLOBAL PHASE 3 STUDY OF EDASALONEXENT IN PEDIATRIC PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY |
| Michaelson, Jacob J | Psychiatry | Simons Foundation Autism Research Initiative | The neuroscience and genetic basis of twice exceptionality: a pilot study |
| Milhem, Mohammed Mahmoud | Internal Medicine | Merck Sharp & Dohme Company | A Multicenter, Open label, Phase III Extension Trial to Study the Long-term Safety and Efficacy in Participants with Advanced Tumors Who are Currently on Treatment or in Follow-up in a Pembrolizumab Trial. |
| Nayak, Manasa Kumar | Internal Medicine | American Heart Association | Role of aerobic glycolysis in platelet function and thrombosis |
| Perlman, Seth Javier | Pediatrics | CSL Behring L.L.C. | Randomized Study of Single vs. Multiple Privigen Dose Regimens |
| Polgreen, Philip Matthew | Internal Medicine | University of Utah | Analysis of Contract Networks in a National sample of Long Term Care facilities |
| Sanchez, Antonio Jaime | Internal Medicine | Enanta Pharmaceuticals, Inc. | A Phase 2 Dose Ranging, Randomized, Double Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects with Primary Biliary Cholangitis (PBC) With or Without an Inadequate Response to UDCA |
| Segal, Rachel Shana | Pediatrics | American Academy of Pediatrics | Healthy Hawkeye Smiles |
| Singh, Namrata | Internal Medicine | Rheumatology Research Foundation | Impact of early therapy with tumor necrosis factor inhibitors on lymphoma risk in patients with rheumatoid arthritis |
| Smith, Richard J | Otolaryngology - Head & Neck Surgery | ArTara Therapeutics | Immunotherapy for the Treatment of Lymphatic Malformations |
| Starner, Timothy Duane Hornick, Douglas B |
Pediatrics | Cystic Fibrosis Foundation Therapeutics, Inc. | Therapeutics Development Center Renewal Progress Report |
| Uc, Ergun Y | Neurology | Parkinson's Foundation | Parkinson's Foundation Center of Excellence |
| Wattiez, Anne-Sophie | Molecular Physiology & Biophysics | American Headache Society | Photosensitivity, tactile hypersensitivity and pain-related facial features as objective biomarkers of chronic PTH |
| Weiss, David S | Microbiology | US National Science Foundation | REU Site: Microbiology at The University of Iowa |
| Zakharia, Yousef | Internal Medicine | Big Ten Cancer Research Consortium | Phase 1b Clinical Trial of Eribulin Mesylate and the PD-L1 Monoclonal Antibody, Avelumab, in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients |
| Zhang, Zeyuan | Anatomy & Cell Biology | American Heart Association | Establish the role of impairment of the adaptive unfolded protein response in defective hepatic autophagy in obesity |
NOVEMBER 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Adams, Christopher Maxin | Internal Medicine | Emmyon, Inc. | Development of Novel Small Molecule Therapies for Skeletal Muscle Atrophy |
| Adams, Denise Allene Martinez | Medicine Administration | Robert Wood Johnson Foundation | Summer Health Professions Education Program |
| Ahmad, Ferhaan | Internal Medicine | MyoKardia, Inc. | MAVERICK-HF |
| Ashwath, Ravi Chandra | Pediatrics | Actelion Clinical Research, Inc. | A prospective, multicenter, open-label, single-arm, Phase 2 study to investigate the safety, tolerability and pharmacokinetics of selexipag in children with pulmonary arterial hypertension |
| Bailey, Jane Allison | Ophthalmology & Visual Sciences | Icahn School of Medicine at Mount Sinai | Surgical Idiopathic Intracranial Hypertension Treatment Trial (SIGHT) |
| Bobb, Morgan R | Emergency Medicine | Emergency Medicine Foundation | Undertriage of Rural Pediatric Trauma Patients: A Statewide Administrative Data Pilot Project |
| Comellas, Alejandro | Internal Medicine | Gala Therapeutics Inc. | A Safety Evaluation of the Gala Airway Treatment |
| Deng, Guorui | Pharmacology | American Heart Association | Mechanisms of angiotensin AT1A signal transduction in AgRP neurons for metabolic rate control |
| Fredericks, Douglas Christian | Orthopaedics and Rehabilitation | Radius Health, Inc. | Assessment of Abaloparatide in a Rat Posterolateral Fusion Model |
| Gaddam, Ravinder Reddy | Internal Medicine | American Heart Association | Gut-microbiota regulated vascular microRNA-204 promotes endothelial dysfunction in diabetes. |
| Gerke, Alicia | Internal Medicine | Mallinckrodt ARD, Inc. | A Phase 4, Multicenter, Randomized, Double Blind, Placebo Controlled Pilot Study to Assess the Efficacy and Safety of H.P. Acthar Gel in Subjects With Pulmonary Sarcoidosis |
| Hasan, David | Neurosurgery | Medicure, Inc. | iSPASM Induced Suppression of Platelets Activity in Aneurysmal SAH Management |
| Howard, Matthew A | Neurosurgery | California Institute of Technology | Casual mapping of emotion networks with concurrent electrical stimulation and fMRI |
| Kaczka, David Walter | Anesthesia | ZOLL Medical Corporation | David Kaczka Paid Consultation to ZOLL Q3 |
| Knudson, C Michael | Medicine Administration | Leidos, Inc. | TPC NCI PDX |
| Milhem, Mohammed Mahmoud | Internal Medicine | Seattle Genetics, Inc. | SGN S40-001: A phase 1, open-label, dose-escalation study of SEA-CD40 in adult patients with advanced malignancies. |
| Parker, Krystal Lynn | Psychiatry | US Department of Health & Human Services, National Institutes of Health | Cerebellar circuits, timing, and cognition |
| Perlman, Stanley | Microbiology | New York Blood Center | Structure-based design of coronavirus subunit vaccines |
| Schlievert, Patrick Michael | Microbiology | Procter & Gamble Company | TSST-1 Toxin Testing |
| Sears, Nathaniel Charles | Ophthalmology & Visual Sciences | American Glaucoma Society | AGS Clinician Scientist-Making and characterizing a hybrid genetic/experimental mouse model of glaucoma |
| Singh, Uday | Pharmacology | American Heart Association | The role of PVN MC4R circuits in obesity-associated hypertension |
| Smith, Richard J | Otolaryngology - Head & Neck Surgery | AdMIRx, Inc. | The Evaluation of Complement Inhibition using an Anti-complement Therapeutic |
| Smith, Richard J Nester, Carla Marie |
Otolaryngology - Head & Neck Surgery | Novartis Corporation | C3 GLOMERULOPATHY - A LONGITUDINAL AND DISCOVERY STUDY |
| Tanas, Munir-Zakary Raja | Pathology | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Upstream requlation of TAZ and YAP in sacromas |
| Van Der Plas, Ellen Aaltje Adriana | Psychiatry | American Cancer Society, Iowa Affiliate | CHILDHOOD CANCER AND PSYCHOSOCIAL DEFICITS: PROSPECTIVE |
| Wood, Kelly Elizabeth | Pediatrics | BiliCam, LLC. | BiliCam (Study Device) |
| Zakharia, Yousef | Internal Medicine | Big Ten Cancer Research Consortium | Single Arm Phase Ib/II Study of Durvalumab and Quadecitabine in Advanced Kidney Cancer |
| Zhan, Fenghuang | Internal Medicine | Myeloma Crowd | Targeting CD24 to eliminate myeloma stem cells |
OCTOBER 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abel, Edwin G | Molecular Physiology & Biophysics | US Department of Health & Human Services, National Institutes of Health | Molecular, Cellular and Circuit Effects of Sleep Deprivation on Hippocampal Function |
| Abreu, Alison Cornelia | Psychiatry | US Department of Health & Human Services, Substance Abuse & Mental Health Services Administration | Collaborative Medication Assisted Treatment in Iowa (Co-MAT-IA) |
| Abreu, Alison Cornelia | Psychiatry | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Collaborative Medication Assisted Treatment for Veterans (VET-MAT-IA) |
| Ahmad, Ferhaan | Internal Medicine | MyoKardia, Inc. | EXPLORER-HCM |
| Anderson, Carryn M | Radiation Oncology | Galera Therapeutics, Inc. | A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Superoxide Dismutase Mimetic GC4419 to Reduce Severe Oral Mucositis (SOM).... |
| Bender, David Paul | Obstetrics & Gynecology | Clovis Oncology, Inc. | GOG-3020/ CO-338-087/ Athena |
| Bernat, John Andrew | Pediatrics | Idorsia Ltd | A multicenter, double-blind, randomized, placebo controlled, parallel-group study to determine the efficacy and safety of lucerastat oral monotherapy in adult subjects with Fabry disease |
| Bollier, Matthew John | Orthopaedics and Rehabilitation | CONMED Corporation | Univ. of Iowa Sports Medicine Fellowship |
| Chan, Carlos Hou Fai | Cancer Center | Memorial Sloan-Kettering Cancer Center | A Phase III Multicenter, Open Label Randomized Controlled Trial of Cefoxitin versus Piperacillin-Tazobactam as Surgical Antibiotic Prophylaxis in Patients Undergoing Pancreatoduodenectomy |
| Choi, Kent Choung | Surgery | Polyphor Ltd | Clinical study No POL7080-010 with murepavadin |
| Comellas, Alejandro | Internal Medicine | University of North Carolina at Chapel Hill | Genomics and Informatics Center for the SubPopulations and InteRmediate Outcomes Measures in COPD Study (SPIROMICS) |
| Coryell, William H | Psychiatry | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Collaborative Medication Assisted Treatment for Veterans (VET-MAT-IA) |
| Dejong, Stacey | Physical Therapy | Medical University of South Carolina | Effects of operant up-conditioning of motor evoked potentials on corticospinal and spinal reflex excitability in people with wrist flexor hypertonia after stroke |
| Dunn-Johnson, Camille C | Otolaryngology - Head & Neck Surgery | Advanced Bionics Corporation | Audiologic Outcomes and Assessment of Real-World Benefits for Cochlear Implantation Using the Advanced Bionics HiFocus SlimJ Electrode |
| Elliott, David E | Internal Medicine | ImmusanT, Inc. | A PHASE 2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY IN HLA-DQ2.5+ ADULTS WITH CELIAC DISEASE TO ASSESS THE EFFECT OF NEXVAX2 ON SYMPTOMS AFTER MASKED GLUTEN FOOD CHALLENGE |
| Ferguson, Nkanyezi Ngwenyama | Dermatology | American Academy of Dermatology | Educational outreach initiative in South Africa concerning the pervasive risk of harmful chemicals contained in over-the-counter topical and cosmetic products |
| Furqan, Muhammad | Internal Medicine | Checkmate Pharmaceuticals | A MULTICENTER, TWO-PART, PHASE 1b CLINICAL STUDY OF CMP-001 IN COMBINATION WITH ATEZOLIZUMAB WITH AND WITHOUT RADIATION THERAPY IN SUBJECTS WITH ADVANCED NON SMALL CELL LUNG CANCER (NSCLC) |
| Hadlandsmyth, Katherine E | Anesthesia | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | VA IPA Katherine Hadlandsmyth-Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain |
| Hadlandsmyth, Katherine E | Anesthesia | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | VA IPA Lori Stout-Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain |
| Hamzeh, Nabeel Y | Internal Medicine | Pulmonary Fibrosis Foundation | CD4 T-cell immunephenotype in hypersenstivity pneumonitis. |
| Hansen, Marlan Rex | Otolaryngology - Head & Neck Surgery | Decibel Therapeutics, Inc. | VGLUT3 Study |
| Harshman, Lyndsay Anne | Pediatrics | Children's Hospital of Philadelphia | Chronic Kidney Disease in Children Prospective Cohort Study |
| Howard, Matthew A | Neurosurgery | Icahn School of Medicine at Mount Sinai | Surgical IIH Treatment Trial |
| Magalhaes-Silverman, Margarida | Internal Medicine | Incyte Corporation | A phase III randomized open-label multi-center study of Ruxolitinib vs. best available therapy in patients with corticosteroid-refractory chronic graft vs host disease after allogeneic stem cell transplantation (REACH 3). |
| Mathews, Katherine Dianne | Pediatrics | rareLife solutions inc. | Cure Duchenne Steroid Education Initiative |
| Mathews, Katherine Dianne | Pediatrics | Institute For Advanced Clinical Trials For Children, Inc. | 2018 InstituteforAdvancedClinicalTrialsforChildren Site Agmt I-ACT[Expires:9-27-2023] |
| McCray, Paul B | Pediatrics | Talee Bio, Inc. | TL-102 Phase I Sponsored Research |
| Miller, Delwyn Deon | Psychiatry | University of California, San Diego | T2 PROTECT AD |
| O'Donnell, Michael A | Cancer Center | Hoosier Cancer Research Network, Inc. | Phase I/II Study of Modern Immunotherapy in BCG-Relapsing Urothelial Carcinoma of the Bladder (ADAPT) HCRN GU16- |
| O'Dorisio, M Sue | Pediatrics | Fraternal Order of Eagles | Molecularly Targeted Therapy for Pediatric Brain Tumors |
| Peterson, Ashley Lea | Pediatrics | Cystic Fibrosis Foundation | Using AAV as a delivery vehicle for gene addition or gene editing in pigs |
| Ryan-Lee, Kathleen Marie | Surgery | Community Foundation of Johnson County, Iowa | Fall Prevention Awareness, Health and Resource Fair |
| Sanchez, Antonio Jaime | Internal Medicine | Salix Pharmaceuticals, Inc. | A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE) |
| Spies, Maria Washington, M Todd |
Biochemistry | University of Kansas Medical Center | APE1 Cleavage Mechanisms during DNA Repair |
| Swenson, Andrea | Neurology | Amylyx Pharmaceuticals, Inc. | Centaur- Open label extension of Phase II Clinical Trial to Evaluate Safety, Tolerability, and Biomarker Engagement of AMX0035 in Patients with ALS |
| Teran, Frida | Neurology | US Department of Health & Human Services, National Institutes of Health | A novel dietary therapy for epilepsy: potential mechanisms of action |
| Thomas, Alexandra Hammond, Donna |
Anesthesia | US Department of Health & Human Services, National Institutes of Health | Phase II Trial of Nicotinamide Riboside for Relief of Taxane-Induced Sensory Neuropathy |
| Tsalikian, Eva | Pediatrics | Amgen, Inc. | Prospective, Multicenter, Single-arm Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Denosumab in Children With Osteogenesis Imperfecta |
| Uc, Aliye | Pediatrics | US Department of Health & Human Services, National Institutes of Health | A Randomized Trial of a Web-based Non-Pharmacological Pain Intervention for Pediatric Chronic Pancreatitis |
| Uthoff, Johanna Mariah | Radiology | American Lung Association | Lung Cancer Risk Assessment Using Quantitative Imaging Features From Nodule, Lung Parenchyma, and Whole Lung |
| Wibbenmeyer, Lucy A | Surgery | MediWound Ltd. | A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid compared to Standard of Care (SOC) treatment-MW2012-01-01 (the Study Drug) |
| Wilken, Jason Mitchell | Physical Therapy | US Department of Defense, Congressionally Directed Medical Research Program | OP170060 Comparative Effect of Commercially Available Custom Dynamic Orthoses (CDOs) |
| Wilken, Jason Mitchell | Physical Therapy | University of Delaware | Objective Clinical Prescription of Passive-Dynamic Ankle-Foot Orthoses to Optimize Patient Outcomes |
| Wolf, Brian Robert | Orthopaedics and Rehabilitation | Vanderbilt University | Operative versus Non-operative Treatment for Atraumatic Rotator Cuff Tears: A Multicenter Randomized Controlled Pragmatic Trial |
| Zakharia, Yousef | Internal Medicine | University of Texas Southwestern Medical Center | Multi-site immune biomarker study - Iowa |
SEPTEMBER 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Adams, Christopher Maxin | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Novel signaling pathways underlying skeletal muscle atrophy |
| Ahrens, Richard C | Pediatrics | Proteostasis Therapeutics, Inc. | A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Pharmacokinetics of PTI-428 in Subjects with Cystic Fibrosis |
| Aldridge, Georgina | Neurology | US Department of Health & Human Services, National Institutes of Health | Cortical Mechanisms in Lewy Body Dementia |
| Anderson, Donald D | Orthopaedics and Rehabilitation | University of Kansas Medical Center Research Institute, Inc. | Accelerating Osteoarthritis Clinical Trials Through Low-Dose Standing CT Imaging |
| Bassuk, Alexander G Mahajan, Vinit Bharati |
Pediatrics | Stanford University | Evaluating GWAS AMD Candidate Loci by Gene Editing in Human iPS Cells |
| Buckwalter, Joseph Addison | Orthopaedics and Rehabilitation | US Department of Defense, Congressionally Directed Medical Research Program | PR172087 - Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA |
| Cadaret, Linda Marie | Internal Medicine | Actelion Clinical Research, Inc. | RETRO |
| Coleman, Mitchell Carl | Radiation Research Laboratory | US Department of Health & Human Services, National Institutes of Health | Do Changes in Thiol Metabolism Mediate Osteoarthritis Progression? |
| Cornell, Robert A | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Dissecting the transcriptional network governing differentiation of periderm |
| Cullen, Joseph John Spitz, Douglas Robert |
Surgery | US Department of Health & Human Services, National Institutes of Health | Exploiting Redox Metabolism Using Pharmacological Ascorbate for Cancer Therapy |
| Dick, David Wayne | Radiology | US Department of Energy | Support for Students, Postdoctoral Fellows and Trainees to Attend the 17th International Workshop on Targetry and Target Chemistry |
| Doerschug, Kevin Clarke | Internal Medicine | ALung Technologies, Inc. | A Prospective, Multi-Center, Randomized, Controlled, Pivotal Trial to Validate the Safety and Efficacy of the Hemolung |
| Gaine, Marie E | Molecular Physiology & Biophysics | Brain & Behavior Research Foundation | Investigating DNA methylation changes in schizophrenia subjects compared to first-degree relatives |
| Gerke, Alicia | Internal Medicine | Boehringer Ingelheim Pharmaceuticals, Inc. | An open-label extension trial to assess the long term safety of nintedanib in patients with 'Systemic Sclerosis associated Interstitial Lung Disease' (SSc-ILD) |
| Greiner, Alexander Michael | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Assessing the Impact of MSX1 in Cardiac Fibrosis and Sudden Cardiac Death |
| Gutmann, Laurie | Neurology | Massachusetts General Hospital | Clinical Coordinating Center Network of Excellence in Neuroscience Clinical Trial |
| Hammond, Donna L | Anesthesia | US Department of Veterans Affairs | VA Vision Contract: Nicotinamide Riboside for the Relief of Painful Dry Eye Syndrome |
| Hodgson-Zingman, Denice Marie | Internal Medicine | Biosense Webster, Inc. | Biosense Webster EP Fellowship Grant 2018-19 academic year |
| Hodgson-Zingman, Denice Marie | Internal Medicine | BIOTRONIK | Biotronik EP Fellowship Grant 2018-19 academic year |
| Idiga, Sharon | Pharmacology | US Department of Health & Human Services, National Institutes of Health | Novel Endocrine Circuit Regulating Sugar Satiety |
| Kardon, Randy Herbert | Ophthalmology & Visual Sciences | US Department of Veterans Affairs | 36C26318P3479 (636D83065) Provide Services with Org Data Answering Inquiries |
| Lentz, Steven | Internal Medicine | Novo Nordisk, Inc. | Pathfinder 8 |
| Loftus, Randy Wayne | Anesthesia | Anesthesia Patient Safety Foundation | Reducing Perioperative S. aureus Transmission via use of an Evidence-Based, Multimodal Program Continually Optimized by Innovative Surveillance (OR PathTrac) |
| Marcinkiewcz, Catherine Anne | Pharmacology | Brain & Behavior Research Foundation | Deconstructing prefrontal connectivity with the dorsal raphe in social behavior |
| Mathews, Katherine Dianne | Pediatrics | Biogen MA, Inc. | Biogen Advisory Board: National Discussion Around Emerging Therapies Advisory Board (East) |
| Mathews, Katherine Dianne | Pediatrics | AMO Pharma | A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Tideglusib Versus Placebo for the Treatment of Children and Adolescents with Congenital Myotonic Dystrophy |
| McCray, Paul B | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides |
| Milhem, Mohammed Mahmoud | Internal Medicine | INC Research, LLC | A Phase 1b, Multicenter, Open-Label Study of DSP-7888 Dosing Emulsion in Combination with Immune Checkpoint Inhibitors Nivolumab or Atezolizumab in Adult Subjects with Advanced Solid Tumors |
| Nester, Carla Marie | Pediatrics | Retrophin, Inc. | A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PARALLEL, ACTIVECONTROL STUDY OF THE EFFECTS OF SPARSENTAN, A DUAL ENDOTHELIN RECEPTOR AND ANGIOTENSIN RECEPTOR BLOCKER, ON RENAL OUTCOMES IN PATIENTS WITH PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS) |
| Nopoulos, Peggy Colleen | Psychiatry | US Department of Health & Human Services, National Institutes of Health | Transfusion of Prematurity Early School Age Follow-up (TOP 5) CCC |
| Nourski, Kirill Vadimovich | Neurosurgery | University of Wisconsin-Madison | Mechanisms of anesthetic-induced unconsciousness |
| Perencevich, Eli N | Internal Medicine | Veterans Affairs Research Foundation | MOU for Subsites- CDC |
| Perencevich, Eli N | Internal Medicine | US Department of Veterans Affairs | Chronic Antibiotic Suppression after Prosthetic Joint Infection |
| Polyak, Steven | Internal Medicine | AbbVie Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Crohn's Disease who Completed the Studies M14-431 or M14-433 |
| Samaniego, Edgar A | Neurology | MicroVention, Inc. | PHIL DAVF Study |
| Segar, Jeffrey L | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Fenoldopam to prevent renal dysfunction in indomethacin treated preterm infants |
| Staber, Janice Marie Rose | Pediatrics | Trinity Partners, LLC | Retrospective chart review of hemophilia A patients with inhibitors treated with rFVIIIFc for ITI |
| Stoltz, David A | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Origins of Cystic Fibrosis Airway Disease |
| Thomas, Geb W Karam, Matthew David |
Orthopaedics and Rehabilitation | Orthopaedic Research & Education Foundation | Benchmarking Expert Performance to Establish Competency in Wire Navigation |
| Tsalikian, Eva | Pediatrics | Takeda Development Center Americas, Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Alogliptin Compared With Placebo in Pediatric Subjects With Type 2 Diabetes Mellitus |
| Vaughan Sarrazin, Mary Susan | Internal Medicine | US Department of Veterans Affairs | 36C26318P3305 (636D83057) Rural Veteran's Access to Va and Non-VA Health Care Providers |
| Washington, M Todd | Biochemistry | US Department of Health & Human Services, National Institutes of Health | Mechanisms of Damaged DNA Replication in Eukaryotes |
| Weiss, David S | Microbiology | US Department of Health & Human Services, National Institutes of Health | Peptidoglycan binding protein specificity and bacterial cell division |
| Xue, Hai-Hui | Microbiology | US Department of Health & Human Services, National Institutes of Health | Ezh2 regulates follicular helper T cell differentiation |
| Zakharia, Yousef | Internal Medicine | Dana-Farber/Partners CancerCare | Phase II study of optimized management of nivolumab based on response in patients with advanced renal cell carcinoma (OMNIVORE) |
AUGUST 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abel, Evan Dale | Internal Medicine | Endocrine Society | Future Leaders Advancing Research in Endocrinology (FLARE): Professional Development |
| Abrams, Thad Eugene | Internal Medicine | US Department of Veterans Affairs | 36C26318P3294 (636D83056) Can Service Dogs Improve Activity and Quality of Life in Veteran's with PTSD - Brian Dake's salary |
| Ahrens, Richard C | Pediatrics | Vertex Pharmaceuticals, Inc. | A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous or Heterozygous for the F508del Mutation |
| Anderson, Michael Gary | Molecular Physiology & Biophysics | US Department of Health & Human Services, National Institutes of Health | Genetic modifiers of Cep290-mediated retinal degeneration |
| Assouline-Dayan, Yehudith | Internal Medicine | Allakos, Inc. | Clinical Research Protocol AK002-003 A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamic Effect of AK002 in Patients with Eosinophilic Gastritis (EG) and/or Eosinop |
| Bassuk, Alexander G | Pediatrics | Stanford University | Mechanism-based therapies for photoreceptor degeneration |
| Bassuk, Alexander G | Pediatrics | Stanford University | Structure and Function of CALPAIN-5 |
| Bathla, Girish | Radiology | Foundation for Sarcoidosis Research | Vessel Wall Imaging in Neurosarcoidosis: Underrecognized, Underdiagnosed and Undertreated |
| Bollier, Matthew John | Orthopaedics and Rehabilitation | Arthroscopy Association of North America | AANA Sports Med Fellowship Grant |
| Bruch, Leslie Anne | Pathology | Intersociety Council for Pathology Information, Inc. | Medical Student Interest Group (MSIG) 2016 Grant Program |
| Channappanavar, Rudragouda | Microbiology | US Department of Health & Human Services, National Institutes of Health | Role of interferon lambda in host protection during aging |
| Cornell, Robert A | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Regulation of the Melanocyte Lineage by the AP2 Transcription Factor Family |
| Cullen, Joseph John | Surgery | US Department of Veterans Affairs | Mechanisms of pharmacological ascorbate inhibition of pancreatic cancer metastases |
| Dayal, Sanjana | Internal Medicine | American Heart Association | Role of gut microbiota in age associated thrombosis |
| De Mik, David Eric | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course - Basic Principles of Fracture Management |
| Derdeyn, Colin P | Radiology | University of Cincinnati | Multi-Arm Optimization of Stroke Thrombolysis (MOST) Stroke Trial |
| Ellingson, Stephanie Jo Kellogg | Radiology | University of Nebraska Medical Center | Introducing Mindful Pause Practice in Sonography Education: A Strategy to Improve Classroom Presence |
| Furqan, Muhammad | Internal Medicine | Pharmaceutical Research Associates | A Randomized Phase 2 Trial of AM0010 in Combination with Pembrolizumab vs Pembrolizumab Alone as First-Line Therapy in Patients with Metastatic NSCLC whose Tumors have High PD-L1 Expression (CYPRESS-1) |
| Garje, Rohan | Internal Medicine | Pfizer, Inc. | (IIR) A phase 1b study of combination of Avelumab and Taxane based chemotherapy in platinum refractory or ineligible metastatic urothelial cancer (AVETAX study) |
| Hillis, Stephen Lawrence | Radiology | US Department of Health & Human Services, National Institutes of Health | Generalized Obuchowski-Rockette Methodology for Analysis of Radiologic Diagnostic Imaging Studies |
| Horwitz, Phillip Andrew | Internal Medicine | Erasmus University Rotterdam | Synergy between PCI with TAXUS and Cardiac Surgery: SYNTAX Extended Survival (SYNTAXES) |
| Jabbari, Ali | Dermatology | US Department of Health & Human Services, National Institutes of Health | Defining T helper cell associated cytokines and mechanisms in Alopecia Areata |
| Jethava, Yogesh Shantilal | Internal Medicine | Janssen Research & Development, Inc. | A phase III randomized, multicenter study of subcutaneous Daratumumab versus active monitoring in subjects with High-risk Smoldering Multiple Myeloma. |
| Karandikar, Nitin Jayant | Pathology | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Immunotherapeutic Regulatory CD8 T cells in Autoimmune Demyelinating Disease |
| Kuperman, Samuel | Psychiatry | Neurocrine Biosciences, Inc. | A Phase 2b, Open-Label Safety and Tolerability Study of Optimized Doses of NBI-98854 for the Treatment of Pediatric Subjects with Tourette Syndrome |
| Leira, Enrique Carlos Adams, Harold P Derdeyn, Colin P Chauhan, Anil Pieper, Andrew A Guierrez, Santiago Samaniego, Edgar A Lentz, Steven Ahmed, Azeemuddin Nugent, Andrew Sean DeJong, Stacey Torner, James C Policeni, Bruno Simmons, Shawn T Hayakawa, Minako Gutmann, Laurie Limaye, Kaustubh S Sharafuddin, Melhem J Horwitz, Phillip Andrew Hasan, David Mathews, Katherine Dianne Tranel, Daniel Thomas Denburg, Natalie Lisa Shim, HyungSub Faine, Brett Anthony Stilley, Joshua David |
Neurology | US Department of Health & Human Services, National Institutes of Health | The University of Iowa's Regional Stroke Research Network |
| Lentz, Steven | Internal Medicine | Apellis Pharmaceuticals, Inc. | An Open Label, Prospective, Study to Assess the Safety, Tolerability, Efficacy and Pharmacokinetics of APL-2 in Patients with Warm Antibody Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD) |
| Liu, Jing | Internal Medicine | American Heart Association | MicroRNA-204 in Aortic Aneurysmal Disease |
| Mohr, Nicholas Matthew | Emergency Medicine | Regents of the University of Minnesota | Hyperbaric Oxygen Brain Injury Treatment (HOBIT) Trial: A multicenter, randomized, prospective phase II adaptive clinical trial evaluating the most effective hyperbaric oxygen treatment paradigm for severe traumatic brain injury |
| Monga, Varun | Internal Medicine | DelMar Pharmaceuticals, Inc. | VAL-083 Phase 3 Study in Temozolomide-Avastin Recurrent GBM (STAR-3): A pivotal randomized, controlled trial of VAL-083 in Patients with recurrent glioblastoma who have failed standard Temozolomide/Radiation Therapy and Bevacizumab |
| Noiseux, Nicolas Olivier | Orthopaedics and Rehabilitation | MicroPort Orthopedics Inc. | Post-Market Surveillance Study of the Wright Medical Technology Metal-on- |
| Ohl, Michael | Internal Medicine | Iowa Department of Public Health | Public Health-Partnered Tele-Medical Pre-Exposure Prophylaxis Delivery in a Rural State (TelePrEP) |
| Phadke, Sneha Deepak | Internal Medicine | Novartis Pharmaceuticals Corporation | BYLieve: A phase II, multicenter, open-label, two-cohort, non-comparative study to assess the efficacy and safety of alpelisib plus fulvestrant or letrozole in patients with PIK3CA mutant, hormone receptor (HR) positive, HER2- negative advanced breast can |
| Piper, Robert C | Molecular Physiology & Biophysics | US Department of Health & Human Services, National Institutes of Health | Ubiquitin-dependent sorting in endosomes and the TGN |
| Polyak, Steven | Internal Medicine | AbbVie Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or are Intolerant |
| Polyak, Steven | Internal Medicine | AbbVie Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or are Intolerant |
| Reisinger, Heather Schacht | Internal Medicine | US Department of Veterans Affairs | 36C26318Q9743 (636D83063) Center for Comprehensive Access & Delivery Research and Evaluation |
| Ripley, Brittany Michelle | Biochemistry | American Heart Association | Rad18: the master regulator of translesion synthesis |
| Russo, Andrew F | Molecular Physiology & Biophysics | University of Rochester | CGRP's effect on hearing and balance in a mouse model of migraine |
| Santillan, Mark Kharim | Obstetrics & Gynecology | American Heart Association | Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia |
| Schmidt, Gregory Allen | Ophthalmology & Visual Sciences | Eye Bank Association of America | Schmidt-EBAA Lindstrom-Assessing the effects of vasoactive intestinal peptide (VIP) on human corneal endothelial cell bioenergentic activity |
| Sharathkumar, Anjali Alatkar | Pediatrics | Sangamo Therapeutics, Inc. | A Phase I/II, Open-Label, Adaptive, Dose -Ranging Study to Assess the Safety and Tolerability of SB-525 [ AAV2/6 hFactor VIII Gene Therapy] in Adult Subjects with Severe Hemophilia A |
| Terry, William Wayne | Cancer Center | Fraternal Order of Eagles | Improving Psych-Social Support for Adolescents and Young Adults with Cancer |
| Tran, Huy T T | Internal Medicine | Intercept Pharmaceuticals, Inc. | A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Obeticholic Acid in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis |
| Weiss, Robert M | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Propagation and Resolution of Injury in Calcific Aortic Valve Disease |
| Weiss, Robert M | Internal Medicine | American Heart Association | Targeting Transient Receptor Potential Cation Channel Subfamily V Member 4 Signaling in Aortic Valve Disease |
JULY 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Aldrich, Benjamin Thomas | Ophthalmology & Visual Sciences | Eye Bank Association of America | EBAA - Lindstrom - Assessing the effects of ripasudil, a novel Rho kinase inhibitor, on human corneal endothelial cell bioenergetic activity |
| Aldrich, Benjamin Thomas | Ophthalmology & Visual Sciences | Eversight | Coenzyme Q10 modulation of mitochondrial function in donor corneal endothelial cells |
| Assouline-Dayan, Yehudith | Internal Medicine | Allergan Sales, LLC | A 46-week, Double-blind, Placebo-controlled, Phase 3 Study with a 6-week Randomized-withdrawal Period to Evaluate the Safety and Efficacy of Relamorelin in Patients with Diabetic Gastroparesis |
| Assouline-Dayan, Yehudith | Internal Medicine | Allergan Sales, LLC | A 52-week, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Relamorelin in Patients with Diabetic Gastroparesis |
| Bernat, John Andrew | Pediatrics | Children's Hospital of Philadelphia | New Approaches in Leukodystrophy-The Myelin Disorders Biorepository and Natural History Project - An Observational Study |
| Block, Robert I | Anesthesia | National Institutes of Health | General Anesthesia During Early Childhood and Brain Development |
| Brennan, Timothy J | Anesthesia | Foundation for Anesthesia Education & Research | MSARF Summer Program 2018 - Host Department Application |
| Carender, Christopher Neil | Orthopaedics and Rehabilitation | DePuy, Inc. | AO Trauma Course North America |
| Diekema, Daniel James | Internal Medicine | Emory University | Assessment and prevention of bioaerosol dispersal by heater-cooler devices |
| Dike, Chinenye Rebecca | Pediatrics | Cystic Fibrosis Foundation | CF Pancreatic Cell Function Rescue by VX-770 and VX-809 |
| Dodd, Rebecca Denise | Internal Medicine | US Department of Defense | Mechanisms of NF1+/- Myeloid Cell Function in MPNSTs |
| Drack, Arlene V | Ophthalmology & Visual Sciences | Medical College of Wisconsin | Defining Structure Function Relationships in Albinism |
| Dupuy, Adam J | Anatomy & Cell Biology | National Institutes of Health | The role germline polymorphisms on ALL susceptibility |
| Erickson, Bradley Allan | Urology | National Institutes of Health | Understanding the Role of Local and Systemic Inflammation in Male Urethral Stricture Disease |
| Evans, Amy Caitlan | Biochemistry | Fight for Sight, Inc. | Fight for Sight 2018-Valdiation of HCN1 Trafficking Partners |
| Faraci, Frank M | Internal Medicine | National Institutes of Health | Central RAAS and Brain Small Vessel Disease |
| Fingert, John Harrison | Ophthalmology & Visual Sciences | Glaucoma Foundation | TGF-Fingert-The Role of Autophagy and Mitochondrial Dysfunction in the Pathogenesis of Exfoliation Glaucoma |
| Fortis, Spyridon | Internal Medicine | ResMed Corp. | Portable Oxygen Concentrator Improvements to Physical Activity, Oxygen Usage, and Quality of Life in Chronic Obstructive Pulmonary Disease Patients using Long-term Oxygen Therapy (POC-STEP) |
| Fraer, Mony | Internal Medicine | Omeros Corporation | A Randomized , Double-blind, Placebo-controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IGAN) |
| Gerke, Alicia | Internal Medicine | Celgene Corporation | A Multicenter, Open-Label Study to Estimate the Effect Sizes of HRCT Endpoints in Response to Glucocorticoid Induction Therapy in Subjects with Pulmonary Sarcoidosis |
| Gordon, David Jon | Pediatrics | St. Baldrick's Foundation | Reversing Resistance to Inhibitors of Ribonucleotide Reductase (RNR) |
| Grumbach, Isabella Maria | Internal Medicine | American Heart Association | Novel models of radiation endotheliopathy |
| Harty, John | Microbiology | National Institutes of Health | Understanding immune regulation in blood-stage malaria |
| Herwaldt, Loreen A | Internal Medicine | US Department of Health & Human Services, Centers for Disease Control & Prevention | SHEPheRD RFTOP 2018 Domain-1-A001 |
| Huang, Chou-Long | Internal Medicine | University of Texas at Dallas | Glomerular Filtration of Sub-nm Gold Nanoparticles |
| Johnson, Chris A | Ophthalmology & Visual Sciences | National Academy of Sciences | NASEM Commissioned Paper Agreement |
| Kaczka, David Walter | Anesthesia | ZOLL Medical Corporation | David Kaczka Paid Consultation to ZOLL Q2 |
| Karwal, Mark William | Cancer Center | NSABP Foundation, Inc. | NSABP PROTOCOL FB-12 |
| Kesler, Kyle Kevin | Orthopaedics and Rehabilitation | Orthopaedic Trauma Association | OTA Fall Residents Comprehensive Fracture Course |
| Kline, Joel N | Internal Medicine | AstraZeneca Pharmaceuticals LP | A Multicentre, Randomized, Double-Blind, Placebo Controlled, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults with Oral Corticosteroid Dependent Asthma (SOURCE) |
| Lindsay, Christopher | Orthopaedics and Rehabilitation | Orthopaedic Trauma Association | OTA Fall Residents Comprehensive Fracture Course |
| Loftus, Randy Wayne | Anesthesia | Draeger Medical GmbH | Evaluation of the efficacy and efficiency of routine cleaning of novel anesthesia machine surfaces |
| Mathews, Katherine Dianne Gutmann, Laurie Adams, Harold P Nopoulos, Peggy Colleen Shy, Michael E Narayanan, Nandakumar |
Neurology | National Institutes of Health | University of Iowa's NeuroNEXT Clinical Research Site |
| Maury, Wendy | Microbiology | National Institutes of Health | Modeling Filovirus Infection of and Trafficking through Skin |
| McCray, Paul B | Pediatrics | Cystic Fibrosis Foundation | A parainfluenza 5 amplifying virus like particle vector for gene delivery |
| Milhem, Mohammed Mahmoud | Internal Medicine | Ultimovacs AS | A Phase I, Open-Label, Multicenter Study Investigating the Tolerability and Efficacy of UV1 Vaccine in First-Line Malignant Melanoma Patients Planned for Treatment with Pembrolizumab |
| Milhem, Mohammed Mahmoud | Cancer Center | Iowa Department of Public Health | Melanoma Research and Activities |
| Miller, Hannah Kay | Biochemistry | American Heart Association | Force-induced apoptosis and the mechanoprotective role of PAK2 |
| Musselman, Catherine Anne | Biochemistry | National Institutes of Health | Molecular mechanisms of histone signaling in a chromatin relevant context |
| Noureddine, Lama | Internal Medicine | University of Kansas Medical Center Research Institute, Inc. | Burden of Imaging in Renal Cysts |
| Ochoa Nunez, Luis Alberto | Pediatrics | Leland Stanford Junior University | Ventricular Pacing in Single Ventricle Congenital Heart Disease - A Multicenter International Study |
| Philibert, Robert Alan | Psychiatry | University of Georgia | Using a Randomized Prevention Trial to Understand the Health Benefits of Supportive Couple Relationships among Rural African American Adults |
| Polyak, Steven | Internal Medicine | Artizan Biosciences | IBD Microbiome Insights (IBD BIOME) |
| Schlievert, Patrick Michael | Microbiology | Procter & Gamble Company | TSST-1 Toxin Testing |
| Shamrock, Alan Gregory | Orthopaedics and Rehabilitation | Medical Device Business Services, Inc (formerly DePuy Synthes) | AO Trauma Course North America |
| Sigmund, Curt D | Pharmacology | National Institutes of Health | Genetic and Signaling Mechanisms in the Central Regulation of Blood |
| Song, Long-Sheng | Internal Medicine | American Heart Association | MG53: A double-Edged Sword in Cardiac T-tubule Damage and REpair |
| Spies, Maria | Biochemistry | US National Science Foundation | EAGER: G4-TIRFM, a platform for massively parallel analysis of non-canonical DNA structures |
| Stapleton, Jack T | Internal Medicine | Research Foundation for The State University of New York | The effect of HIV and cocaine abuse on semen exosome composition and function |
| Strack, Stefan | Pharmacology | Ataxia Charlevoix-Saguenay Foundation | Unbiased sacsin client identification and genetic intervention in a mouse model of ARSACS |
| Thiel, William | Internal Medicine | American Heart Association | Generation of Cardiac Specific Aptamer Ligands |
| Turvey, Carolyn Louise | Psychiatry | US Department of Health & Human Services, Agency for Healthcare Research & Quality | Development of a Targeted Patient Portal Intervention to Improve Depression Treatment Adherence, Satisfaction, and Outcomes |
| Weeks, Daniel L | Biochemistry | National Institutes of Health | Amyloids, aggregates and nucleolar activity in Xenopus development |
| Wilken, Jason Mitchell | Physical Therapy | Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | MORE Resiliency in the Rehabilitation of Active Duty Service members |
| Yahr, Timothy Lee Ellermeier, Craig D |
Microbiology | National Institutes of Health | 25th Annual Midwest Microbial Pathogenesis Conference |
JUNE 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Ahrens, Richard C | Pediatrics | Vertex Pharmaceuticals, Inc. | A Post-approval Observational Study to Evaluate the Long-term Effectiveness and Safety of Orkambi in US Patients Who completed Study VX12-809-105 Part A |
| Anderson, Michael Gary | Molecular Physiology & Biophysics | Glaucoma Foundation | Robust Mouse Models of Exfoliation Glaucoma |
| Assouline-Dayan, Yehudith | Internal Medicine | Celgene Corporation | Assessment of the Content Validity and Reproducibility of the Dysphagia Daily Symptom Diary (DSD) in Patients with Eosinophilic Esophagitis |
| Attanasio, Massimo | Internal Medicine | Iowa Fraternal Order of the Eagles | Single Cell Analysis of Senescent Cells After Tubular Injury |
| Briasoulis, Alexandros | Internal Medicine | University of Kansas Medical Center Research Institute, Inc. | PROVIDE-HF |
| Cadaret, Linda Marie | Internal Medicine | United Therapeutics Corporation | SOUTHPAW OL |
| Chitneni, Shobha | Internal Medicine | Genentech, Inc. | PHASE III, OPEN-LABEL, MULTICENTER, RANDOMIZED STUDY EVALUATING THE EFFICACY AND SAFETY OF ATEZOLIZUMAB (MPDL3280A, ANTIPD-L1 ANTIBODY) IN COMBINATION WITH CARBOPLATIN PACLITAXEL OR ATEZOLIZUMAB IN COMBINATION WITH CARBOPLATIN NAB-PACLITAXEL VERSUS CARBO |
| Ciliberto, Michael Anthony | Pediatrics | GW Pharmaceuticals | A double-blind, randomized, placebo-controlled study to investigate the efficacy and safety of cannabidiol (GWP42003-P, CBD) as add-on therapy in patients with tuberous sclerosis complex who experience inadequately-controlled seizures |
| Colgan, John David | Internal Medicine | When Everyone Survives Leukemia Research Foundation | The cell-cycle regulator GON4L in acute lymphoblastic leukemia |
| Cornell, Robert A | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Functional tests of non-coding DNA variants associated with risk for orofacial clefting |
| Fisher, Rory A | Pharmacology | US Department of Health & Human Services, National Institutes of Health | RGS6 in mesolimbic circuits as a therapeutic target for alcohol use disorders |
| Fuentes, Ernesto J | Biochemistry | US Department of Health & Human Services, National Institutes of Health | PAS domain and redox regulation of the S. aureus SrrB sensor histidine kinase |
| Furqan, Muhammad | Internal Medicine | Merck Sharp & Dohme Company | A Phase III, Randomized, Double-blind Trial of Platinum Doublet Chemotherapy +/- Pembrolizumab as Neoadjuvant/Adjuvant Therapy for Participants with Resectable Stage IIB or IIIA NSCLC (Keynote-671) |
| Gutierrez, Santiago | Neurology | Siemens Medical Solutions USA, Inc. | C-arm Cone Beam Study |
| Hamzeh, Nabeel Y | Internal Medicine | National Jewish Health | A Prospective Study of T cell Immune-phenotype and Disease Outcome in Pulmonary Sarcoidosis |
| Hyer, Daniel E | Radiation Oncology | US Department of Health & Human Services, National Institutes of Health | Sharpening the edge in pencil-beam proton therapy: an aftermarket collimation system to better spare normal tissue during radiation treatment |
| Jiang, Bing-Hua | Pathology | US Department of Health & Human Services, National Institutes of Health | Chromium in carcinogenesis and angiogenesis |
| Kuehn, Markus H | Ophthalmology & Visual Sciences | Boehringer Ingelheim Pharma GmbH & Co. | Boehringer - Effects of AOC3 Inhibition in Glaucoma |
| Kuperman, Samuel | Psychiatry | US Department of Health & Human Services, National Institutes of Health | 5/7-Collaborative Genomic Studies of Tourette Disorder |
| Langbehn, Douglas Robert | Psychiatry | University College London | Variability in cognitive impairment in Huntington's disease: the effect of environment on cognitive reserve |
| Li, Luyuan Park, Brian Ji Hoon |
Neurosurgery | Fraternal Order of Eagles | Exploring the effects of radiation therapy on neurotrophic factors |
| Liu, Ling-Zhi Jiang, Bing-Hua |
Pathology | US Department of Health & Human Services, National Institutes of Health | Mechanism of lung cancer resistance to tyrosine kinase inhibitor and radiation treatments |
| Mathews, Katherine Dianne | Pediatrics | Capricor Therapeutics | A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL EVALUATING THE SAFETY AND EFFICACY OF INTRAVENOUS DELIVERY OF ALLOGENEIC CARDIOSPHERE-DERIVED CELLS IN SUBJECTS WITH DUCHENNE MUSCULAR DYSTROPHY (HOPE-2) |
| Maury, Wendy | Microbiology | US Department of Health & Human Services, National Institutes of Health | Mechanisms and consequences of Plasmodium/Ebola virus co-infections |
| Mokadem, Mohamad | Internal Medicine | Iowa Fraternal Order of the Eagles | Jackson Laboratory Genetic Mouse Model (UCP3 KO Mouse) |
| Monga, Varun | Internal Medicine | St. Baldrick's Foundation | Improve Access to Clinical Trials for AYA with Cancer |
| Nagpal, Prashant | Radiology | Radiological Society of North America | Comparison of Free-breathing Self-gated 3D Cardiac MRI with Manifold Reconstruction Algorithms and Standard Breath-hold Sequence in Patients with and Without COPD |
| Narayanan, Nandakumar | Neurology | US Department of Health & Human Services, National Institutes of Health | Timing and dopamine in frontostriatal circuits |
| Nester, Carla Marie | Pediatrics | Achillion Pharmaceuticals, Inc | A Phase 2, Proof-of-Concept, Randomized, Double-Blinded, Placebo-Controlled Study of ACH-0144471 Treatment for 6 Months in Patients with C3 Glomerulopathy (C3G). |
| Perlman, Stanley | Microbiology | Kansas State University | Small Molecule Protease Inhibitors against MERS-CoV |
| Pieper, Andrew A | Psychiatry | Proneurotech, Inc. | Neuroprotective efficacy of P7C3 analogs in blast-mediated traumatic brain injury |
| Saha, Punam Kumar | Radiology | US Department of Health & Human Services, National Institutes of Health | CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD |
| Salgado-Pabon, Wilmara | Microbiology | US Department of Health & Human Services, National Institutes of Health | Enterotoxin-Mediated Development of Staphylococcus aureus Infective Endocarditis |
| Sears, Nathaniel Charles | Ophthalmology & Visual Sciences | IDx, LLC | IDx Study to validate algorithm(s) for predicting thresholded visual field from retinal layer thickness maps in OCTs |
| Sharafuddin, Melhem J | Surgery | Bard Peripheral Vascular, Inc. | Bard UltraScore Study |
| Sindt, Christine W | Ophthalmology & Visual Sciences | MDM Optical, LLC | (IIS) MDM Optical LLC-Scleral Lens Design Using Ocular Surface Elevation |
| Singh, Madhu V | Internal Medicine | Iowa Fraternal Order of the Eagles | 2018 Iowa State FOE Grant - Dr. Madhu Singh |
| Singh, Minati | Internal Medicine | Iowa Fraternal Order of the Eagles | 2018 Iowa State FOE Grant - Dr. Minati Singh |
| Sinn, Patrick Ladd | Pediatrics | US Department of Health & Human Services, National Institutes of Health | Spread and Release of Measles in the Airways |
| Sivitz, William I | Internal Medicine | Iowa Fraternal Order of the Eagles | Effect of a Mitochondrial-Targeted Antioxidant on Insulin Production by Pancreatic Islet Cells |
| Starner, Timothy Duane | Pediatrics | Vertex Pharmaceuticals, Inc. | A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of VX-659 in combination with Tezacaftor/Ivacaftor in Subjects With Cystic Fibrosis Who Are Heterozygous for F508del and a Minimal Function Mutation (F/MF) |
| Starner, Timothy Duane | Pediatrics | Vertex Pharmaceuticals, Inc. | A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del Mutation (F/F) |
| Thiel, William | Internal Medicine | US Department of Health & Human Services, National Institutes of Health | Deciphering mechanisms of vascular disease with cell and process specific ligands |
| Vaidya, Jatin Girish | Psychiatry | National Center for Responsible Gambling | Impulsivity in adolescent children with a family history of gambling disorder |
| Wall, Michael | Ophthalmology & Visual Sciences | EMMES Corporation | VFRC NAION Trial_Emmes |
| Yan, Ziying | Anatomy & Cell Biology | University of Kansas Medical Center Research Institute, Inc. | Human Bocavirus 1 (Hbov1) Capsid Entry And Intracellular Trafficking Of Polarized Human Airway Epithelium |
| Yeaman, Charles A | Anatomy & Cell Biology | US Department of Health & Human Services, National Institutes of Health | Regulation of Epithelial Cell Polarity by Ral-Exocyst Complexes |
| Zakharia, Yousef | Internal Medicine | Clovis Oncology, Inc. | A Phase 2, Open-Label Study of Rucaparib in Patients with Locally Advanced or Metastatic Urothelial Carcinoma (ATLAS) |
MAY 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Chitneni, Shobha | Internal Medicine | Genentech, Inc. | A phase II, open-label, multicenter, randomized study to investigate the efficacy and safety of atezolizumab (Anti-PD-L1 Antibody) compared with docetaxel in patients with non-small cell lung cancer after failure with platinum-containing chemotherapy (OAK |
| Coryell, William | Psychiatry | Quintiles, Inc. | A 6-Month, Multicenter, Double-Blind, Randomized, Flexible-Dose, Parallel-Group Study |
| Doddapattar, Prakash | Internal Medicine | American Heart Association | Mechanistic role of integrin alpha9beta1 in atherosclerosis |
| Ferguson, Polly | Pediatrics | CARRA, Inc. Childhood Arthritis and Rheumatology Research Alliance | CARRA- AF Study Coordinator |
| Gonzalez Bosquet, Jesus | Obstetrics & Gynecology | American Board of Obstetrics and Gynecology | Integrative model to select patients for optimal primary surgical outcomes in high-grade serous ovarian cancer |
| Harata, Nobutoshi | Molecular Physiology & Biophysics | US Department of Defense, Congressionally Directed Medical Research Program | PR172016 Acute hypoglycemia and inhibitory synaptic transmission in brain neurons |
| Hefti, Marco Matthias | Pathology | Children's Hospital of Philadelphia | INO Neuroprotection Following Pediatric Cardiac Arrest |
| Hodgson-Zingman, Denice | Internal Medicine | St. Jude Medical, Inc. | EP Fellowship Grant 2018-19 academic year |
| Hoffman, Eric | Radiology | National Jewish Health | Genetic Epidemiology of COPD |
| Hong, Sandy | Pediatrics | CARRA, Inc. Childhood Arthritis and Rheumatology Research Alliance | CARRA- AF Study Coordinator |
| Hornick, Douglas | Internal Medicine | Insmed, Inc. | A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center Study to Assess the Efficacy, Safety and Tolerability, and Pharmacokinetics of INS1007 Administered Once Daily for 24 Weeks in Subjects with Non-Cystic Fibrosis Bronchiectasis - |
| Kardon, Randy Herbert | Molecular Physiology & Biophysics | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | VA-PO: Kardon/Hedberg Refine existing methodologies for quantitative and qualitative analysis of mouse to human optic nerve |
| Kassan, Modar | Internal Medicine | American Heart Association | miR-204/Sirt1 axis induces endothelial dysfunction by targeting vascular serotonin in diabetes/obesity |
| Long, Jeffrey | Psychiatry | Cleveland Clinic Lerner College of Medicine | Immune Mechanisms Underlying the Neuroprotective Effects of Physical Activity in Human and Mouse Models of Genetic Risk for Alzheimer's Disease |
| McCray, Paul | Pediatrics | University of Georgia | A parainfluenza virus 5 vector for CRISPR-Cas9 gene edting of CFTR locus |
| Milhem, Mohammed | Internal Medicine | Genmab A/S | First-in-human, open-label, dose-escalation trial with expansion cohorts to evaluate safety of Axl-specific antibody-drug conjugate (HuMax-AXL-ADC) in patients with solid tumors. |
| Narayanan, Nandakumar | Neurology | Eli Lilly & Company | Effect of LY3154207 on Cognition in Mild-to-Moderate Parkinson's Disease Dementia |
| Perencevich, Eli | Internal Medicine | US Department of Veterans Affairs | Checklist to Prevent MRSA Surgical Site Infections |
| Perencevich, Eli | Internal Medicine | US Department of Veterans Affairs | Measuring Transmissibility of E coli vs Klebsiella and The CREATE MRSA surgical Site infection Bundle 2.0 implementation Study |
| Schultz, Michael | Radiology | ViewPoint Molecular Targeting, LLC | Targeted Radionuclide Therapy for Metastatic Melanoma |
| Sharafuddin, Melhem | Surgery | Washington University | C-TRACT TRIAL |
| Shy, Michael | Neurology | University College London | Muscle MRI in Charcot Marie Tooth disease |
| Shy, Michael | Neurology | Charcot-Marie-Tooth Association | Molecular Biomarkers for CMT Disease |
|
Strack, Stefan |
Pharmacology | US Department of Health & Human Services, National Institutes of Health | Targeting mitochondrial fission for neuroprotection in diabetic neuropathy |
| Sylvers, Kelli | Biochemistry | American Heart Association | Lipase inhibition by ANGPTL3 and ANGPTL8 |
| Thomas, Christie | Internal Medicine | Regulus Therapeutics Inc. | A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Efficacy, Pharmacodynamics, and Pharmacokineticsof RG-012 for Injection Administered Every 2 Weeks in Patients with Alport Syndrome |
| Thomas, Christie | Internal Medicine | Regulus Therapeutics Inc. | A Phase 1, Open-Label Study to Evaluate the Safety, Pharmacodynamics, and Pharmacokinetics of Subcutaneous RG-012 for Injection, Including Its Effect on Renal microRNA-21, in Subjects with Alport Syndrome |
| Vikram, Ajit | Internal Medicine | American Heart Association | Gut-microbiota regulated vascular miR-204 promotes diabetes-associated endothelial dysfunction |
| Yadav, Ravi Prakash | Molecular Physiology & Biophysics | Knights Templar Eye Foundation, Inc. | Molecular Mechanisms of AIPL1 and its TPR domain in Leber congenital amaurosis |
APRIL 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abel, E. Dale | Internal Medicine | National Institutes of Health | OPA1 an Estrogen-Mediated Modulator of Platelet Hyperactivation |
| Cadaret, Linda | Internal Medicine | United Therapeutics Corporation | SOUTHPAW |
| Chan, Carlos | Surgery | Central Surgical Association Foundation | Effect of Biliary Bacterial Contamination in Peritoneal Metastasis of Peri-Ampullary Cancers |
| Coryell, William | Psychiatry | Janssen Research and Development, LLC | A Double-blind, Randomized, Psychoactive Placebo-controlled, Study to Evaluate the Efficacy and Safety of 3 Fixed Doses (28 mg, 56 mg and 84 mg) of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms |
| Erickson, Bradley | Urology | Urotronic, Inc. | ROBUST II Clinical Study Re-Establishing Of Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease |
| Farooq, Umar | Internal Medicine | Kite Pharma, Inc. | A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy of Axicabtagene Ciloleucel vs Standard of Care Therapy in Subjects with Relapsed / Refractory Diffuse Large B Cell Lymphoma (ZUMA-7) |
| Gutierrez, Santiago | Neurology | Medtronic, Inc. | Medical Education Neurovascular- Medtronic |
| Hefti, Marco | Pathology | Children's Hospital of Philadelphia | Ischemix SRA Large Animal PoC Efficacy Trial for CMX-2043 |
| Hrabe, Jennifer | Surgery | Entac Medical, Inc. | Spectral Density in GI Impairment |
| Idiga, Sharon | Pharmacology | American Heart Association | Novel Endocrine Circuit Regulating Sugar Satiety |
| Milhem, Mohammed | Internal Medicine | Mayo Clinic | Phase 2 Clinical Trials Program for Experimental Therapeutics Clinical Trials Network |
| Miller, Benjamin | Orthopaedics and Rehabilitation | Cleveland Clinic Foundation | Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma |
| Newell, John | Radiology | Columbia University | Subclinical interstitial lung disease in MESA and FAR-ILD |
| Noterman, Maria | Psychiatry | National Institutes of Health | A Novel Role of Cav1.2 in Mitochondria |
| Noureddine, Lama | Internal Medicine | Hope Medical Enterprises, Inc. | Observational Follow-up to ST-001 Calciphylaxis Pain Treatment with Intravenous Sodium Thiosulfate |
| Ohl, Michael | Internal Medicine | Gilead Sciences, Inc. | A brief, pragmatic experiment to determine the feasibility of a public-health-partnered tele-pharmacist model for PrEP delivery in a rural state |
| Perencevich, Eli | Internal Medicine | US Department of Veterans Affairs | Work for the Center for Comprehensive Access & Delivery Research and Evaluation |
| Ponce, Jessica | Internal Medicine | National Institutes of Health | Dual Roles of Cyclin C in Heart Disease |
| Sapouckey, Sarah | Pharmacology | American Heart Association | Mechanisms of the Arcuate Nucleus Leptin-Angiotensin Interaction in the Control of Metabolism |
| Schmidt, Warren | Internal Medicine | Conatus Pharmaceuticals, Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects with Decompensated Non-Alcoholic Steatohepatitis (NASH) Cirrhosis |
| Sieren, Jessica | Radiology | Exemplar Genetics | Exemplar Genetics |
| Stapleton, Jack | Internal Medicine | Health Resources & Services Administration | OP EARLY INTERVENTION SERVICES WITH RESPECT TO HIV DISEASE |
| Swenson, Andrea | Neurology | Massachusetts General Hospital | Phase II Clinical Trial to Evaluate Safety, Tolerability, and Biomarker Engagement of AMX0035 in Patients with ALS |
| Tsalikian, Eva | Pediatrics | Ascendis Pharma A/S | A Multicenter, Phase 3, Open-Label, 26-Week Trial Investigating the Safety, Tolerability and Efficacy of TransCon hGH Administered Once Weekly in Children with Growth Hormone Deficiency (GHD |
| Wibbenmeyer, Lucy | Surgery | Stratatech | A Phase III Open-Label, Controlled Randomized, Multicenter Study Evaluating the Efficacy and Safety of Stratagraft Skin Tissue in Promoting Autologous Skin Tissue Regeneration of Complex Skin Defects Due to Thermal Burns that Contain Intact Dermal Element |
| Wilken, Jason | Physical Therapy | Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | The BADER Consortium: Maximizing Out Patient Rehabilitation Effectiveness (MORE) |
| Winokur, Patricia | Institute for Clinical and Translational Science | National Institutes of Health | The University of Iowa Clinical and Translational Science Award |
| Zakharia, Yousef | Internal Medicine | Dana-Farber/Partners CancerCare | A Phase II Study of TAK-228 in patients with previously treated metastatic renal cell carcinoma |
| Zakharia, Yousef | Internal Medicine | Astellas Pharma Global Development, Inc. | A phase I study of ASP8374, an Immune Checkpoint Inhibitor, in subjects with advanced solid tumors. |
| Zakharia, Yousef | Internal Medicine | Calithera BioSciences, Inc. | A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study Comparing CB-839 in Combination with Everolimus (CBE) vs. Placebo with Everolimus (PboE) in Patients with Advanced or Metastatic Renal Cell Carcinoma (RCC) |
| Zakharia, Yousef | Internal Medicine | Hoosier Cancer Research Network, Inc. | Single Arm Phase II Study of Ipilimumab and Nivolumab as Adjuvant Therapy for Resected Mucosal Melanoma (SALVO study) |
| Zarei, Sanam | Molecular Physiology & Biophysics | Howard Hughes Medical Institute | Can Increasing CDP-Ribitol by ISPD Gene Transfer Improve Dystroglycan Glycosylation and Muscle Function in Limb Girdle Muscular Dystrophy 2I (LGMD2I) Mice? |
MARCH 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Assouline-Dayan, Yehudith | Internal Medicine | Allergan Sales, LLC | A 12 WEEK, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED, PHASE 3 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF RELAMORELIN IN PATIENTS WITH DIABETIC GASTROPARESIS |
| Assouline-Dayan, Yehudith | Internal Medicine | Shire Human Genetic Therapies, Inc. | A Phase 3, Multicenter, Open-Label Continuation Study with Budesonide Oral Suspension (BOS) for Adolescent and Adult Subjects with Eosinophilic Esophagitis (EoE) |
| Bender, David | Obstetrics & Gynecology | GOG Foundation | A Phase III, MULTICENTER, RANDOMIZED, placebo-controlled Study OF Atezolizumab Versus Placebo IN COMBINATION WITH Paclitaxel, carboplatin, and Bevacizumab for PATIENTS WITH Newly diagnosed stage III/IV ovarian, ... |
| Bhama, Jay | Surgery | St. Jude Medical Business Services, Inc. | Investigation of HearTMatE2 LVAD with sEnsing CardioMEMs Technology in Heart Failure Patients (INTELLECT2-HF) |
| Cadaret, Linda | Internal Medicine | Duke Clinical Research Institute | VICTORIA HF Registry |
| Chatterjee, Snehajyoti | Molecular Physiology & Biophysics | Nellie Ball Trust | Investigating the role of the schizophrenia-associated gene Nr4A2 in cognition using single-neuron RNA sequencing |
| Choi, Kent | Surgery | Octapharma Pharmazeutika | A phase III, randomized, double-blind, multicenter study to assess the efficacy and safety of OCTAPLEX, a four-factor prothrombin complex concentrate (4F-PCC), compared to the 4F-PCC Beriplex P/N (Kcentra), for the reversal of vitamin K antagonist induced |
| Claflin, Kristin | Pharmacology | National Institutes of Health | Identification of a novel neural circuit regulating energy expenditure and glucose homeostasis |
| Comellas, Alejandro | Internal Medicine | GlaxoSmithKline LLC | A randomized, double-blind, Sponsor open, placebo-controlled, 52 week study evaluating the effect of danirixin (GSK1325756) on lung function and health related quality of life in participants with mild to moderate Chronic Obstructive Pulmonary Disease (CO |
| Comellas, Alejandro | Internal Medicine | COPD Foundation | RETHINC |
| Derdeyn, Colin | Radiology | Penumbra, Inc. | Penumbra DSMB Consulting Services Agreement |
| Dolan, Lori | Orthopaedics and Rehabilitation | Green Sun Medical | Green Sun Medical Methods Consulting |
| Dunn-Johnson, Camille | Otolaryngology - Head & Neck Surgery | Cochlear Americas | Adult Cochlear Implant Candidacy & Outcomes: a Retrospective Analysis |
| Fraer, Mony | Internal Medicine | Arbor Research Collaborative for Health | Peritoneal Dialysis Outcomes and Practice Patterns Study, 2017-2020 |
| Goodheart, Michael | Obstetrics & Gynecology | University of Chicago | Phase II Trial of Metformin Subcontract- U of Chicago |
| Grumbach, Isabella | Internal Medicine | US Department of Veterans Affairs | Calmodulin kinase II inhibition as novel molecular treatment of hypertension |
| Gutmann, Laurie | Neurology | Charcot-Marie-Tooth Association | Early Phase Treatment Trials of CMT2A |
| Hadlandsmyth, Katherine | Anesthesia | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Telephone-Cognitive Behavioral Therapy in Veterans at Risk for Chronic Postsurgical Pain |
| Hammond, Donna | Anesthesia | National Institutes of Health | Mechanistic Studies of the Natural Product Nicotinamide Riboside for Relief of Painful Sensory Neuropathy |
| Harland, Karisa | Emergency Medicine | Iowa Department of Public Health | Sexual Violence Prevention Evaluation |
| Haskell, Sarah | Pediatrics | National Institutes of Health | Impact of disruptions in the serotonin system on cardiac development |
| Ho, Beng Choon | Psychiatry | Nellie Ball Trust | Brain Neuroimaging Correlates of Schizophrenia Polygenic Risk Score |
| Horwitz, Phillip | Internal Medicine | Edwards Lifesciences LLC | EARLY TAVR |
| Huang, Chou-Long Sigmund, Curt |
Internal Medicine | National Institutes of Health | Iowa Training Program in Kidney and Hypertension Research |
| Jalal, Diana | Internal Medicine | AstraZeneca Pharmaceuticals LP | A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease |
| Knudson, C Michael | Pathology | Terumo Corporation | Clinical Effectiveness of Standard Versus Mirasol-treated Apheresis Platelets in Patients with Hypoproliferative Thrombocytopenia (MIPLATE Trial) |
| Law, Ian | Pediatrics | Rock for the Heart Foundation | Atrial Tachycardia Pacing Therapy in Congenital Heart (AT-PATCH) |
| Leira, Enrique | Neurology | University of Cincinnati | ARCADIA study |
| Lieberman, Scott | Pediatrics | National Institutes of Health | Cytokines driving T cell dysregulation in lacrimal gland autoimmunity |
| Link, Brian Krall | Cancer Center | Mayo Clinic | Genetic Predictors of Early Clinical Failure in Diffuse Large B Cell Lymphoma |
| Liu, Ling-Zhi | Pathology | American Cancer Society | Chromium-Mediated Signaling Pathways in Carcinogenesis |
| Liu, Ling-Zhi | Pathology | National Institutes of Health | New Mechanism of Arsenic Carcinogenesis |
| Magnotta, Vincent | Radiology | National Institutes of Health | Research 3T MRI Connectome Upgrade |
| Mathews, Katherine | Pediatrics | Acceleron Pharma, Inc. | A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ACE-083 in Patients with Facioscapulohumeral Muscular Dystrophy |
| Milhem, Mohammed | Internal Medicine | TESARO, Inc. | A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors |
| Milhem, Mohammed | Internal Medicine | Novartis Pharmaceuticals Corporation | Modular phase 2 study to link combination immune-therapy to patients with advanced solid and hematologic malignancies - Module 9: PDR001 plus LAG525 for patients with advanced solid and hematologic malignancies |
| Parker, Krystal | Psychiatry | Nellie Ball Trust | Targeting comorbid depression in schizophrenia with cerebellar stimulation |
| Paulsen, Jane | Psychiatry | National Institutes of Health | Preparing for preventive clinical trials in Huntington's disease |
| Polgreen, Philip | Internal Medicine | US Department of Veterans Affairs | An M-health Intervention to Increase the Activity Levels of Rural Veterans (MapTrek) |
| Price, David | Biochemistry | National Institutes of Health | RNA Polymerase II Elongation Control |
| Reinking, Benjamin | Pediatrics | Janssen Research & Development, Inc. | A Prospective, Open-Label, Active-Controlled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Rivaroxaban for Thromboprophylaxis in Pediatric Subjects 2 to 8 Years of Age after the Fontan Procedure |
| Singh, Namrata | Internal Medicine | Duke University | A Randomized, double-blind, placebo-controlled, multicenter, phase III efficacy and safety study of subcutaneous anakinra (Kineret) in patients with Still's disease (SJIA and AOSD) followed by an open-label extension. |
| Stevens, Hanna | Psychiatry | Nellie Ball Trust | The Effects of Redox Dysregulation on Cortical Interneuron Development and Schizophrenia-like Behaviors |
| Swenson, Andrea | Neurology | Cytokinetics, Inc. | Cytokinetics - CY-5022 |
| Tyler, Richard | Otolaryngology - Head & Neck Surgery | University of Southern California | Hyperacusis focus groups |
| Vaughan Sarrazin, Mary | Internal Medicine | US Department of Veterans Affairs | Conduct work to enhance the innovative data analysis and management capabilities and techniques in Iowa City |
| Velez, Gabriel | Ophthalmology | National Institutes of Health | Structure-function studies of Calpain-5 in hereditary uveitis |
| Wilson, Mary | Internal Medicine | US Department of Veterans Affairs | The Role of Exosomes in the Pathogenesis of Leishmaniasis |
FEBRUARY 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Cadaret, Linda | Internal Medicine | United Therapeutics Corporation | ADAPT |
| Chauhan, Anil | Internal Medicine | National Institutes of Health | Targeting Pyruvate Kinase M2: A novel strategy to combat thrombo-inflammation |
| Comellas, Alejandro | Internal Medicine | Emergent Biosolutions, Inc. | A Randomized, Double-Blind, Placebo-Controlled Dose Ranging Study |
| DeCorte, Benjamin | Neurology | National Institutes of Health | Dopaminergic regulation of striatal ensembles during cognitive performance: Implications for Parkinson's disease |
| Erickson, Bradley | Urology | Boston Scientific Corporation | 2018-2019 Urology Fellowship |
| Fingert, John Anderson, Michael Scheetz, Todd |
Ophthalmology & Visual Sciences | National Institutes of Health | Exome Studies of Pigmentary Glaucoma |
| Flynn, Ryan | Radiation Oncology | Elekta, Inc. | Elekta's Usability Testing Activities at the University of Iowa |
| Gordon, David | Pediatrics | National Institutes of Health | Gene expression signature based screening in Ewing sarcoma |
| Grobe, Justin | Pharmacology | American Heart Association | Hypothalamic mechanisms of cardiometabolic and obstetric disease |
| Hansen, Marlan Guyman, C Allan |
Otolaryngology - Head & Neck Surgery | National Institutes of Health | Reduction of intracochlear fibrosis and bacterial infection using photopolymerized durable zwitterionic coatings on cochlear implant biomaterials |
| Harrison, Heather Thomas, Geb |
Orthopaedics and Rehabilitation | Pediatric Orthopaedic Society of North America | The Design and Validation of a Wire Natigation Simulator for Pediatric Supracondylar Humerus Fractures |
| Hitchon, Patrick | Neurosurgery | Pfizer, Inc. | A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Staphylococcus Aureus 4-Antigen Vaccine (SA4Ag) in Adults Undergoing Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Hoffman, Eric | Radiology | University of California, San Francisco | SPIROMICS II: Biological underpinnings of COPD heterogeneity and progression |
| Irani, Kaikobad | Internal Medicine | US Department of Veterans Affairs | SIRTUIN1-mediated inhibition of P66shc lysine acetylation as a novel treatment for diabetic vasculopathy |
| Levy, Barcey | Family Medicine | Oregon Health & Science University | A cluster-randomized trial comparing team-based versus primary care clinician-focused advance care planning in practice-based research networks |
| Mangalam, Ashutosh | Pathology | National Institutes of Health | Linking diet, gut microbiota and autoimmune disease: Bacteria induced phytoestrogen metabolites impact immune function in Experimental Autoimmune Encephalitis |
| Milhem, Mohammed | Internal Medicine | Idera Pharmaceuticals, Inc. | A Phase 1/2 Study to Assess the Safety and Efficacy of Intratumoral IMO-2125 in Combination with Ipilimumab or Pembrolizumab in Patients with Metastatic Melanoma |
| Nance, Christopher | Neurology | Vertex Pharmaceuticals, Inc. | Clinical Trial - Study drug VX16-150-102 |
| Nester, Carla | Pediatrics | Alexion Pharmaceuticals, Inc. | A PHASE 3, OPEN-LABEL, MULTICENTER STUDY OF ALXN1210 IN CHILDREN AND ADOLESCENTS WITH ATYPICAL HEMOLYTIC-UREMIC SYNDROME (aHUS) |
| Nester, Carla | Pediatrics | ChemoCentryx, Inc. | A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of Avacopan (CCX168) in Patients with C3 Glomerulopathy |
| Noureddine, Lama | Internal Medicine | Hope Pharmaceuticals | A Phase 3, Intravenous Sodium Thiosulfate for Acute |
| Packer, Hans Williams, Aislinn |
Psychiatry | Nellie Ball Trust | Analyzing the functional consequences of a genetic risk factor for schizophrenia using genome editing of patient-derived stem cells |
| Purnell, Benton | Neurology | National Institutes of Health | Determining the effect of circadian phase on seizure induced respiratory arrest and death |
| Sharafuddin, Melhem | Surgery | GE Healthcare | Parallel-Group, Placebo-Controlled Randomized Study Investigating the Effect of Intravenous Iso-osmolar Iodinated Contrast Material Iodixanol (Visipaque Injection 320 mgI/mL) on Renal Function in Adults with Chronic Kidney Disease (CKD) Stage III or Stage |
| Solimeo, Samantha | Internal Medicine | US Department of Veterans Affairs | Identifying Barriers to Implementation and Spread of Specialty Care Telehealth PACT Serving Rural Veterans |
| Tanas, Munir | Pathology | US Department of Veterans Affairs, Iowa City Veterans Affairs Medical Center | Upstream regulation of TAZ and YAP in sarcomas: towards combinatorial |
| Varga, Steven | Microbiology | Iowa State University | Nanoparticle-based vaccination against RSV |
| Vyas, Yatin | Pediatrics | National Institutes of Health | Role of WASp in Golgi dispersal response to DNA damage in lymphocytes |
| Weigel, Ronald | Surgery | University of Ghana | WACCBIP Wellcome Trust Deltas Student-Visitor Fellowship Award |
| Wemmie, John | Psychiatry | National Institutes of Health | Basolateral amygdala circuits in defensive behavior regulation |
| Zhang, Jian | Pathology | Ohio State University | Regulation of T Follicular Helper Cells in SLE by E3 Ubiquitin Ligase Cbl-b |
JANUARY 2018
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Adams, Christopher | Internal Medicine | US Department of Veterans Affairs | Prevention and Treatment of Skeletal Muscle Atrophy |
| Ahrens, Richard | Pediatrics | Proteostasis Therapeutics, Inc. | A Multi-Center, Randomized, Placebo-Controlled, Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, & Drug Interactions of PTI-801 in Healthy Volunteers, & Safety, Tolerability, & Pharmacokinetics in Subjects with CF |
| Allen, Bryan | Radiation Oncology | Gateway for Cancer Research | Pharmacological Ascorbate Combined with Radiation and Temozolomide in GBM |
| Allen, Lee-Ann | Internal Medicine | National Institutes of Health | Francisella tularensis reprograms human neutrophils |
| Anderson, Carryn | Radiation Oncology | Soligenix, Inc. | A Pivotal, Double-Blind, Randomized, Placebo-Controlled, Multinational Study Of Sgx942 (Dusquetide) For The Treatment Of Oral Mucositis In Patients Being Treated With Concomitant |
| Artemyev, Nikolai | Molecular Physiology & Biophysics | National Institutes of Health | Molecular Mechanisms of Photoreceptor G Protein Signaling |
| Bender, David | Obstetrics & Gynecology | Regeneron Pharmaceuticals, Inc. | GOG-3016 / R2810-ONC-1676 |
| Chitneni, Shobha | Internal Medicine | Genentech, Inc. | A phase III, open-label, randomized study of atezolizumab (MPDL3280A, anti-PD-L1 antibody) in combination with carboplatin+paclitaxel with or without bevacizumab compared with carboplatin+paclitaxel+bevacizumab in chemotherapy-naive patients with stage IV |
| Collins, Laura | Pathology | Mallinckrodt Pharmaceuticals | CELLEX Access Route and Diagnosis Program |
| Davis, Benjamin | Internal Medicine | AstraZeneca Pharmaceuticals LP | A Multicenter, Randomized, Double-blind, Parallel Group, Placebo controlled, Phase 3b Study to Evaluate the Safety and Efficacy of Benralizumab 30 mg sc in Patients with Severe Asthma Uncontrolled on Standard of Care Treatment |
| Dejong, Stacey | Physical Therapy | University of California, Irvine | Genetic variation, stress, and functional outcomes after stroke rehabilitation |
| Norris, Andrew Engelhardt, John |
Pediatrics | National Institutes of Health | Splanchno-Hormonal Mechanisms of Cystic Fibrosis Related Diabetes |
| Engelhardt, John | Anatomy & Cell Biology | Cystic Fibrosis Foundation | Modulating Regenerative Abilities of Airway Stem Cells for CF Therapy |
| Engelhardt, John | Anatomy & Cell Biology | Talee Bio, Inc. | TaleeBio - TL-101 Phase 1 Sponsored Research |
| Hamzeh, Nabeel | Internal Medicine | National Jewish Health | Epigenetic Regulation of Altered T-cell Immunity in Sarcoidosis |
| Hamzeh, Nabeel | Internal Medicine | National Jewish Health | Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency |
| Hamzeh, Nabeel | Internal Medicine | National Jewish Health | Role of T-bet+CD11 c+ B Cells in Sarcoidosis |
| Huang, Chou-Long | Internal Medicine | University of Texas Southwestern Medical Center | Preventive Hypertension and Sympathetic Overactivation by Targeting Phosphate |
| Huang, Chou-Long | Internal Medicine | Boehringer Ingelheim Pharmaceuticals, Inc. | Boehringer Ingelheim Pharmaceuticals Research Project #2 |
| Krysan, Damian | Pediatrics | University of Pennsylvania | A. mutans-C Albicans Interactions syngergize teh virulence of cariogenic biofilms |
| Kuperman, Samuel | Psychiatry | Neurocrine Biosciences, Inc. | A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose-Optimization Study to Assess the Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects with Tourette Syndrome |
| Larson Ode, Katie | Pediatrics | Regents of the University of Minnesota | The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic CF Patients |
| Lizarraga, Ingrid | Cancer Center | Alliance Foundation Trials, LLC | Comparison of Operative to Monitoring and Endocrine Therapy (COMET) Trial for low risk DCIS: A Phase III Prospective Randomized Trial |
| Macfarlane, Donald | Internal Medicine | Shire plc | Pilot study of lexeme-based medical note creation for patients with hemophilia |
| Magalhaes-Silverman, Margarida | Internal Medicine | Incyte Corporation | A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination with Corticosteroids for the Treatment of First-Line Acute Graft-Vs-Host Disease. |
| Mathews, Katherine | Pediatrics | Reata Pharmaceuticals, Inc. | A PHASE 2 STUDY OF THE SAFETY, EFFICACY, AND PHARMACODYNAMICS OF RTA 408 IN THE TREATMENT OF FRIEDREICH'S ATAXIA |
| Mathews, Katherine | Pediatrics | Takeda Development Center Americas, Inc. | A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm Study to Evaluate Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adult Subjects With Friedreich Ataxia |
| Nauseef, William | Internal Medicine | National Institutes of Health | Determinants of human neutrophil fate after phagocytosis |
| Polyak, Steven | Internal Medicine | AbbVie, Inc. | A Phase 3 Multicenter, Open-Label Extension (OLE) Study to Evaluate the Long-Term Safety and Efficacy of ABT-494 in Subjects with Ulcerative Colitis (UC) |
| Rauckhorst, Adam | Biochemistry | American Diabetes Association | Regulation of Hepatic Glucose Metabolism by a Candidate Mitochondrial Glutamine Carrier |
| Sah, Rajan | Internal Medicine | American Diabetes Association | SWELL1 regulation of -cell excitability and insulin secretion |
| Sanchez, Antonio | Internal Medicine | AbbVie, Inc. | A Single Arm, Open-label Study Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment Naive Adults with Chronic Hepatitis C Virus (HCV) Genotype 1, 2, 4, 5 or 6 Infection and Compensated Cirrhosis |
| Schnieders, Michael | Biochemistry | US National Science Foundation | CAREER: Chemical Theory for the Protein Crystal Folding Problem |
| Sebag, Julien | Molecular Physiology & Biophysics | National Institutes of Health | Investigating the requirement of MRAP2 for ghrelin function |
| Sharathkumar, Anjali | Pediatrics | Bioverativ, Inc. | A Non-controlled, Open-Label, Multicenter, Study of Efficacy of |
| Staber, Janice | Pediatrics | Bioverativ, Inc. | EXTEN-A |
| Tarini, Beth | Pediatrics | University of Colorado Denver | NewSTEPS360 |
| Wall, Michael | Neurology | Icahn School of Medicine at Mount Sinai | Surgical IIH Treatment Trial |
| Wei, Shunguang | Internal Medicine | National Institutes of Health | Targeting TACE, a novel approach to the treatment of sympathetic excitation in heart failure. |
| Yang, Ling | Anatomy & Cell Biology | American Diabetes Association | Mechanisms underlying itrosylation-mediated dysregulation of hepatic autophagy in obesity |
DECEMBER 2017
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Ahrens, Richard | Pediatrics | Savara Pharmaceuticals | A Phase III, randomized, double-blind, placebo-controlled study of AeroVanc for the treatment of persistent methicillin-resistant Staphylococcus aureus lung infection in cystic fibrosis patients |
| Cadaret, Linda | Internal Medicine | Actelion Clinical Research, Inc. | SERENADE: A multi-center, double-blind, placebo-controlled Phase 2b study to evaluate the efficacy and safety of macitentan in subjects with heart failure with preserved ejection fraction and pulmonary vascular disease |
| Chauhan, Anil | Internal Medicine | American Heart Association | Novel Mechanisms linking thromosis and inflammation |
| Fick, Andrea | Obstetrics & Gynecology | Telligen Community Initiative | Sonographer Training for Telemedicine for High-Risk Pregnancies |
| Fiedorowicz, Jess | Psychiatry | Washington University | Resource Development to Facilitate sIRB Review for Multi-site Research |
| Gantz, Bruce | Otolaryngology - Head & Neck Surgery | NIH | Iowa Cochlear Implant Clinical Research Center VII |
| Grumbach, Isabella | Internal Medicine | NIH | Mitochondrial CaMKII drives smooth muscle migration and neointimal hyperplasia |
| Gurung, Prajwal | Internal Medicine | NIH | Elucidating cellular and molecular mechanisms regulating SHP1-mediated inflammatory skin disease |
| Hansen, Marlan | Otolaryngology - Head & Neck Surgery | Decibel Therapeutics, Inc. | Collaboration with Decibel |
| Hirsch, Raphael | Pediatrics | NIH | Molecular and Cellular Research to Advance Child Health |
| Horwitz, Phillip | Internal Medicine | Novartis Pharmaceuticals Corporation | PARADISE-MI |
| Imai, Yumi | Internal Medicine | American Diabetes Association | Regulation of insulin secretion by lipid droplet proteins! |
| Krysan, Damian | Pediatrics | NIH | Complex haploinsufficiency based genetic analysis of C.albicans pathhogenesis |
| Larson, Robert | Internal Medicine | NIH | Cardiac Sensory-Sympathetic-Angiotensinergic Mechanisms in Hypertrophic Cardiomyopathy |
| Lentz, Steven | Internal Medicine | Novo Nordisk, Inc. | Alleviate 1 |
| Martinez, Denise | Medicine Administration | Robert Wood Johnson Foundation | Summer Health Professions Education Program |
| Meier, Jeffery Price, David |
Internal Medicine | NIH | Transcriptional Mechanisms Controlling HCMV Infection |
| Paulsen, Jane | Psychiatry | CHDI Foundation, Inc. | HDClarity |
| Polyak, Steven | Internal Medicine | TARGET PharmaSolutions | A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease |
| Robertson, Janice | Molecular Physiology & Biophysics | NIH | Debugging eukaryotic membrane protein expression in E. coli using single-molecule fluorescence microscopy |
| Shaffer, Joseph | Radiology | Brain & Behavior Research Foundation | THE EFFECTS OF CEREBELLAR STIMULATION ON FUNCTIONAL ACTIVITY AND CONNECTIVITY IN SCHIZOPHRENIA |
| Sharathkumar, Anjali | Pediatrics | Washington University | Heartland Sickle Cell Disease Network |
| Strack, Stefan | Pharmacology | Jordan's Guardian Angels | Deciphering molecular pathogenesis and developing a mouse models of PPP2R5D mutations |
| Swenson, Andrea | Neurology | Flex Pharma, Inc. | Flex Pharma clinical trial drug Flex-787-203 |
| Wall, Michael | Ophthalmology & Visual Sciences | Icahn School of Medicine at Mount Sinai | SiihTT VFRC-Surgical IIH Treatment Trial |
| Yan, Ziying | Anatomy & Cell Biology | Cystic Fibrosis Foundation Therapeutics, Inc. | Novel Parvovirus Vector for Cystic Fibrosis Gene Therapy |
NOVEMBER 2017
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abushahin, Laith | Internal Medicine | Merck Sharp & Dohme Company | A Phase III Randomized Open-label Study of Single Agent Pembrolizumab vs Physicians' Choice of Single Agent Docetaxel, Paclitaxel, or Irinotecan in Subjects with Advanced/Metastatic Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus that have Pro |
| Ahern, Christopher | Molecular Physiology & Biophysics | NIH | The Facility for Atomic Mutagenesis |
| Bernat, John | Pediatrics | Protalix Biotherapeutics | A Phase 3, Open Label, Switch Over Study to Assess the Safety, Efficacy and Pharmacokinetics of pegunigalsidase alfa (PRX-102) 2 mg/kg Administered by Intravenous Infusion Every 4 Weeks for 52 weeks in Patients with Fabry Disease Currently Treated with En |
| Cadaret, Linda | Internal Medicine | Actelion Pharmaceuticals, Ltd. | OPsumit Historical USers cohort study (OrPHeUS), a Multicenter, retrospective chart review of first-time Opsumit (macitentan) users in the United States |
| Davis, Andrew | Otolaryngology - Head & Neck Surgery | American Academy of Otolaryngology-Head and Neck Surgery Foundation | SOD Mimics Enhace Chemoradiation Responses of HNSCC via Oxidative Stress |
| Fairley, Janet | Dermatology | Regents of the University of California, San Francisco | A Phase I, Open-Label, Multicenter Trial Exploring the Safety and Tolerability of Autologous Polyclonal Regulatory T Cell Therapy in Adults with Active Pemphigus |
| Gantz, Bruce | Otolaryngology - Head & Neck Surgery | Cochlear Americas | Association Between Intra-Operative Cochlear Response Telemetry and Hearing Preservation (CREST) |
| Hendrickson, Nathan Willey, Michael |
Orthopaedics and Rehabilitation | Orthopaedic Trauma Association | Perioperative Screening and Nutritional Supplementation in Orthopaedic Trauma Patients |
| Hoffman, Eric | Radiology | National Jewish Health | (1 of 3) Genetic Epidemiology of COPD |
| Lentz, Steven | Internal Medicine | Novo Nordisk, Inc. | Explorer 4 |
| Long, Jeffrey Mills, James |
Psychiatry | CHDI Foundation, Inc. | Modeling progression in Huntington's disease: analysis and validation across multiple studies |
| Mathews, Katherine Trout, Christina |
Pediatrics | Parent Project Muscular Dystrophy | PPMD CDCC Liaison Grant 2018 |
| Murray, Jeffrey | Institute for Clinical and Translational Science | Burroughs Wellcome Fund | BWF Physician-Scientist Institutional Award Planning Grant Application |
| Shy, Michael | Neurology | Flex Pharma, Inc. | Flex-Pharma Clinical trial of study drug Flex-787-204 |
| Sivitz, William | Internal Medicine | George Washington University | Glycemia Reduction Approaches for Diabetes: A Comparative Effectiveness Study (GRADE) |
| Stone, Edwin | Ophthalmology & Visual Sciences | Grand Chapter of Iowa Order of the Eastern Star | Sramek Age-Related Macular Degeneration Fund |
| Stone, Edwin | Ophthalmology & Visual Sciences | Renaissance Charitable Foundation Inc. | Diagnostics and Surgical Treatment Fund for Retinal Diseases |
| Wood, Kelly | Pediatrics | Seattle Children's Research Institute | Pediatric Quality Measures Program- Dissemination and Implementation of Child Health quality Measures Cooperative Research Grant |
| Yang, Ling | Anatomy & Cell Biology | NIH | Integration of Inflammatory Signaling and the Unfolded Protein Response by Nitrosylation Signaling in Obesity |
| Zakharia, Yousef | Internal Medicine | Merck Sharp & Dohme Company | A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Pembrolizumab as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy |
| Zakharia, Yousef | Internal Medicine | NewLink Genetics Corporation | A Phase 2/3 (Adaptive Design) Study of the Concomitant Administration of Indoximod or Placebo plus Pembrolizumab or Nivolumab in Adult Patients with Unresectable Stage III or Stage IV Malignant Melanoma |
OCTOBER 2017
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abel, Ted | Molecular Physiology & Biophysics | University of Pennsylvania | Sleep/Wake Fragmentation with Age: Molecular Mechanisms |
| Ahmad, Ferhaan | Internal Medicine | University of Kentucky | Role of myocyte Na+ dysregulation in diabetic heart disease |
| Assouline-Dayan, Yehudith | Internal Medicine | Seres Therapeutics, Inc. | AN OPEN-LABEL EXTENSION OF STUDY SERES-012 EVALUATING SER-109 IN ADULT SUBJECTS WITH RECURRENT CLOSTRIDIUM DIFFICILE INFECTION (RCDI) |
| Badovinac, Vladimir | Pathology | University of Minnesota | Alterations in CD4 T cells during sepsis |
| Bernat, John | Pediatrics | Protalix Biotherapeutics | A Multi Center Extension Study of PRX-102 Administered by Intravenous Infusions Every 2 Weeks for up to 60 Months to Adult Fabry Patients |
| Cadaret, Linda | Internal Medicine | Bayer Healthcare AG | PANACHE |
| Cadaret, Linda | Internal Medicine | Amgen, Inc. | GALACTIC-HF |
| Ciliberto, Michael | Pediatrics | GW Pharmaceuticals | Amendment # 3 GW Pharmaceuticals - An open label extension study to investigate the safety of cannabidiol (GWP42003-P; CBD) in children and adults with inadequately controlled Dravet or Lennox-Gastaut Syndromes |
| Coryell, William | Psychiatry | University of Michigan | Electronic Bridge to Mental Health (eBridge) for College Students_Supplement |
| Diekema, Daniel | Pathology | bioMerieux, Inc. | VITEK 2 and VITEK 2 Compact AF04 Antifungal Susceptibility Tests |
| Engelhardt, John | Anatomy & Cell Biology | Vertex Pharmaceuticals, Inc. | Development of Ferret Models for CF using VX-770 & guide RNAs |
| Gerke, Alicia | Internal Medicine | United Therapeutics Corporation | A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung DiseaseRIN-PH-201 |
| Hornick, Douglas | Internal Medicine | Parion Sciences | A Phase 2a, Randomized, Double-blind, Placebocontrolled, |
| Horwitz, Phillip | Internal Medicine | Daiichi Sankyo, Inc. | ENVISAGE TAVI-AF |
| Howard, Matthew | Neurosurgery | Johns Hopkins University | Targeted Neuroplasticity Training (TNT) |
| Huang, Chou-Long | Internal Medicine | Boehringer Ingelheim Pharmaceuticals, Inc. | Boehringer Ingelheim Pharmaceuticals Research Agreement |
| Krysan, Damian | Pediatrics | University of Toronto | Targeting Hsp90 in cryptococcal fungal pathogenesis |
| Langbehn, Douglas | Psychiatry | University College London | TREAT-HD: targeting neurodegeneration in Huntington's disease |
| Lee, Amy | Molecular Physiology & Biophysics | NIH | Regulation of auditory calcium channels |
| Milhem, Mohammed | Internal Medicine | Sarcoma Alliance for Research through Collaboration | A Phase II Randomized Controlled Trial of Neoadjuvant Pembrolizumab with Radiotherapy and Adjuvant Pembrolizumab in Patients with High-Risk, Localized Soft Tissue Sarcoma of the Extremity |
| Milhem, Mohammed | Internal Medicine | TRACON Pharmaceuticals, Inc. | A Randomized Phase 3 Trial of TRC105 and Pazopanib vs Pazaopanib Alone in Patients with Advanced Angiosarcoma (TAPPAS) |
| Milhem, Mohammed | Internal Medicine | Immunocore Limited | A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared with Investigator's Choice in HLA-A*0201 Positive Patients with Previously Untreated Advanced Uveal Melanoma |
| Milhem, Mohammed | Internal Medicine | Checkmate Pharmaceuticals | A Multicenter, Open Label, Phase 1B Clinical Study of CMP-001 In Combination With Pembrolizumab In Subjects Who Have Been Treated With Pembrolizumab For Advanced Melanoma. |
| Milhem, Mohammed | Internal Medicine | Polynoma LLC | A Multicenter, Double-blind, Placebo-controlled, Adaptive Phase 3 Trial of POL-103A Polyvalent Melanoma Vaccine in Post-resection Melanoma Patients with a High Risk of Recurrence Protocol: 103A-301 |
| Miller, Delwyn | Psychiatry | Alkermes, Inc. | A Phase 3 Study to assess the Long Term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831 in Subjects with Schizophrenia, Schizophreniform Disorder, or Bipolar Disorder |
| Nuangchamnong, Nina | Obstetrics & Gynecology | Washington University | Reproductive Scientist Development Program (RSDP) |
| O'Donnell, Michael | Molecular Physiology & Biophysics | SynderBio, Inc. | STTR: Improved detection of bladder cancer recurrence using a biophysical biomarker |
| Ohl, Michael | Internal Medicine | US Department of Veterans Affairs | Contract Services to support Rural Health Resource Center |
| Otero, Jesse | Orthopaedics and Rehabilitation | OrthoCarolina Research Institute | Surgical Treatment of Chronic Periprosthetic Joint Infection |
| Polyak, Steven | Internal Medicine | Gilead Sciences, Inc. | A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Crohn's Disease |
| Polyak, Steven | Internal Medicine | AbbVie, Inc. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis |
| Polyak, Steven | Internal Medicine | Gilead Sciences, Inc. | A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Testicular Safety of Filgotinib in Adult Males with Moderately to Severely Active Ulcerative Colitis |
| Schmidt, Warren | Internal Medicine | Gilead Sciences, Inc. | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (NASH) |
| Schmidt, Warren | Internal Medicine | Gilead Sciences, Inc. | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis |
| Schmidt, Warren | Internal Medicine | Allergan Sales, LLC | STELLARIS: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis |
| Sharafuddin, Melhem | Surgery | Medtronic Vascular, Inc. | IN.PACT AV Access Study |
| Storm, Douglas | Urology | Allergan, Inc. | 191622-120; BOTOX in the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity in Patients 5 to 17 Years of Age |
| Tansey, Michael | Pediatrics | Jaeb Center for Health Research Foundation, Inc. | A Study to Assess Continuous Glucose Sensor Profiles in Healthy Non-Diabetic Subjects |
| Taylor, Eric | Biochemistry | Cirius Therapeutics, Inc. | Cirius Therapeutics, Inc. |
| Vigil Gonzales, Carlos | Internal Medicine | Syros Pharmaceuticals | A Biomarker-directed Phase 2 Trial of SY-1425 a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) |
| Voigt, Michael | Internal Medicine | Cirius Therapeutics, Inc. | A Phase 2, Randomized, Double-Blind, Placebo-Controlled, 12-Month, Multiple-Dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC 0602K in Patients with NASH (EMMINENCETM) |
| Wilson, Mary | Internal Medicine | Banaras Hindu University | Visceral Leishmaniasis in Bihar State, India |
| Young, Samuel | Anatomy & Cell Biology | West Virginia University Research Corporation | Development of the Calyx of Held |
| Zhan, Fenghuang | Internal Medicine | Leukemia & Lymphoma Society | CLINICAL INVESTIGATION OF CD38+/LIGHT CHAIN +/CD24+ AS STEM CELL MARKERS IN MYELOMA |
SEPTEMBER 2017
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Abou Alaiwa, Mahmoud | Internal Medicine | University of Texas Health Science Center at Tyler | Porcine Model of Nontuberculous Mycobacterial Lung Disease |
| Abushahin, Laith | Cancer Center | PPD Development, LP | NIH/NCI/NCTN/PPD High Performing Site Initiative |
| Ahern, Christopher | Molecular Physiology & Biophysics | NIH | Photochemical determination of sodium channel voltage-dependent gating and composition |
| Assouline-Dayan, Yehudith | Internal Medicine | Seres Therapeutics, Inc. | A Phase 2 Multicenter, RandomizeEd, Double-Blind, Placebo-COntrolled, Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium difficile Infection (CDI) in Adults Who Have Received. |
| Bollier, Matthew | Orthopaedics and Rehabilitation | CONMED Corporation | University of Iowa Sports Medicine Fellowship |
| Bollier, Matthew | Orthopaedics and Rehabilitation | Arthrex, Inc. | Arthrex Sports Medicine Fellowship |
| Cadaret, Linda | Internal Medicine | Bayer Healthcare AG | PARSIFAL |
| Davis, Benjamin | Internal Medicine | Aimmune Therapeutics | REAL-WORLD AR101 MARKET-SUPPORTING EXPERIENCE STUDY IN PEANUT-ALLERGIC CHILDREN AGES 4 TO 17 YEARS (RAMSES) |
| Espinosa, Madelyn | Pathology | NIH | Targeting inflammation and immune response in HNSCC therapy |
| Furqan, Muhammad | Internal Medicine | Big Ten Cancer Research Consortium | A Phase II Trial of Chemotherapy plus Pembrolizumab in Patients with Advanced NSCLC Previously Treated with PD-1 or PD-L1 Inhibitor |
| Gerke, Alicia | Internal Medicine | United Therapeutics Corporation | An Open-Label Extension study of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung Disease |
| Giudici, Michael | Internal Medicine | Cardionomic, Inc. | Cardionomic Inc |
| Giudici, Michael | Internal Medicine | Boston Scientific Corporation | Strategic Management to Optimize Response To Cardiac Resynchronization Therapy SMART CRT |
| Henry, Michael | Molecular Physiology & Biophysics | SynderBio, Inc. | SBIR: Improved preparation of cell suspensions for single cell genomics |
| Hodgson-Zingman, Denice | Internal Medicine | Biosense Webster, Inc. | Biosense Webster EP Fellowship Grant 2017-18 academic year |
| Huang, Chou-Long | Internal Medicine | NIH | Regulation of renal sodium and potassium transport by WNK kinases |
| Klein, Jonathan | Pediatrics | Mallinckrodt Pharmaceuticals | Multicenter,Prospectively Defined Observational Registry With Retrospective Data Collection,Evaluating Premature & Term-Near Term Neonates With Pulmonary Hypertension Receiving Inhaled Nitric Oxide via Invasive or Non invasive Ventilator Support at US Cen |
| Leira, Enrique Pieper, Andrew Rahmatalla, Salam Schnell, Thomas |
Neurology | NIH | Assessment of the effects of emergent helicopter transport on stroke in a rodent model |
| Luo, Yi | Urology | NIH | Inhibition of TLR4 for Treatment of Cystitis Pain |
| Magnotta, Vincent Wemmie, John |
Radiology | NIH | Cerebellar Metabolism, Neural Circuits, and Symptoms in Bipolar Disorder |
| Miller, Delwyn | Psychiatry | Janssen Research and Development, LLC | A Phase 2b/3 Randomized, Double-blind, Placebo-Controlled, Parallel Group, Multicenter Study Investigation the Efficacy and Safety of JNJ-54861911 in Subjects who are Asymptomatic at Risk for Developing Alzheimer's Dementia |
| Narayanan, Nandakumar | Neurology | NIH | Mid-frontal delta/theta rhythms and cognitive control in Parkinson's Disease |
| Perepu, Usha | Internal Medicine | Academic and Community Cancer Research United | ACCRU-SC-1601: A Phase III, Randomized, Double-Blind Study Evaluating the Safety of Two Doses of Apixaban for Secondary Prevention of Cancer Related Venous Thrombosis in Subjects who have Completed at Least Six Months of Anticoagulation Therapy. |
| Samaniego, Edgar | Neurology | Medicure, Inc. | Determination of the Safety of Tirofiban in the Treatment of Ruptured and Unruptured Aneurysms |
| Sato, Mariko | Pediatrics | Children's Hospital of Philadelphia | Bristol Myers Squibb |
| Schmidt, Warren | Internal Medicine | US Department of Veterans Affairs | Neoplastic Interactions of hepatitis C virus with telomerase |
| Sharafuddin, Melhem | Surgery | Bolton Medical, Inc. | A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with Traumatic Injury of the Descending Thoracic Aorta |
| Sharathkumar, Anjali | Pediatrics | Baxalta Innovations GMBH | POST-MARKETING non-interventional safety evaluation of obizur in the treatment of bleeding episodes for patients with acquired hemophilia A |
| Sheldon, Ryan | Biochemistry | NIH | Regulation of Hepatic Lipogenesis by a Mitochondrial Pyruvate Carrier-Citrate Carrier Axis |
| Snyder, Peter | Internal Medicine | US Department of Veterans Affairs | Epithelial Sodium Channel Trafficking |
| Starner, Timothy | Pediatrics | Vertex Pharmaceuticals, Inc. | A Phase 2, Randomized, Double-blind, Controlled Study to Evaluate the Safety and Efficacy of VX-659 Combination Therapy in Subjects Aged 18 Years and Older With Cystic Fibrosis |
| Vaughan Sarrazin, Mary | Internal Medicine | NIH | Dosing of Direct Oral Anticoagulants for stroke prevention in Atrial Fibrillation: Patterns, Consequences, and Guidance |
| Wilken, Jason | Physical Therapy | Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | The BADER Consortium: Maximizing Out Patient Rehabilitation Effectiveness (MORE) |
| Winokur, Patricia | Internal Medicine | Brigham and Women's Hospital | Influenza Vaccine - INVESTED study |
| Young, Samuel | Anatomy & Cell Biology | Michael J. Fox Foundation for Parkinson's Research | Production of HdAd typed 5 LRRK2 expression vectors |
| Zakharia, Yousef | Internal Medicine | AstraZeneca AB | A Phase III, Open Label, Randomized, Controlled, Multi-Center Study to Assess the Efficacy and Safety of Savolitinib vs Sunitinib in Patients with MET-Driven, Unresectable and Locally Advanced, or Metastatic Papillary Renal Cell Carcinoma (PRCC) |
AUGUST 2017
| PI | Department | Sponsor | Title |
|---|---|---|---|
| Ahrens, Richard | Pediatrics | Vertex Pharmaceuticals, Inc. | Phase 3b, Randomized, Double-blind, Placebocontrolled, Parallel Group Study to Assess the Safety, Efficacy, and Tolerability of Tezacaftor/Ivacaftor (TEZ/IVA) in an Orkambiexperienced Population Who Are Homozygous forthe F508del-CFTR Mutation |
| Brenner, Charles | Biochemistry | ChromaDex, Inc. | Maternal and Neonatal Effects of NR |
| Coleman, Mitchell | Orthopaedics and Rehabilitation | National Institutes of Health | Do Changes in Thiol Metabolism Mediate Osteoarthritis Progression? |
| Dayal, Sanjana | Internal Medicine | National Institutes of Health | Peroxide mediated prothrombotic effects of aging |
| Durgempudi Tripura, Sundara | Anesthesia | B. Braun Medical Inc. | Beta Implementation OR PathTrac at the University of Iowa Hospitals & Clinics |
| Ebach, Dawn | Pediatrics | University of North Carolina at Chapel Hill | Anti-TNF Monotherapyversus Combination Therapy with Lose Dose Methotrexate in Pediatric Crohn's disease (COMBINE) |
| Faraci, Frank | Internal Medicine | US Department of Veterans Affairs | Role of PPAR-gamma in cerebral endothelium |
| Furqan, Muhammad | Internal Medicine | Big Ten Cancer Research Consortium | A Phase Ib/II Study of Anti-PD-1 Antibody Pembrolizumab and Imprime PGG for Patients with Metastatic Non-Small Cell Lung Cancer After Progression on First-Line Chemotherapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017 |
| Gerke, Alicia | Internal Medicine | US Food & Drug Administration | Defining the natural history of sarcoidosis in a retrospective cohort to inform design of clinical trials |
| Grumbach, Isabella | Internal Medicine | US Department of Veterans Affairs | CaMKII as a regulator of diabetic retinopathy |
| Hasan, David | Neurosurgery | Advanced Endovascular Therapeutics | Evaluation of a Nanometer-Scale Hemocompatible and Antithrombotic Coating Technology for Commercially Available Intracranial Stents and Flow Diverters |
| Hinton, Antentor | Internal Medicine | Burroughs Wellcome Fund | Mechanisms for Insulin-dependent regulation of skeletal muscle mitochondria by OPA1 |
| Hodgson-Zingman, Denice | Internal Medicine | Medtronic, Inc. | EP Fellowship Grant |
| Jabbari, Ali | Dermatology | National Institutes of Health | Defining T helper cell associated cytokines and mechanisms in Alopecia Areata |
| Kang, Sinyoung Brennan, Timothy |
Anesthesia | National Institutes of Health | TRPA1 in Postoperative Pain |
| Karandikar, Nitin | Pathology | Iowa City Veterans Affairs Medical Center | Immunotherapeutic Regulatory CD8 T cells in Autoimmune Demyelinating Disease |
| Mathews, Katherine | Pediatrics | PTC Therapeutics, Inc. | An Open-Label, Safety Study for Previously Treated Ataluren (PTC124) Patients with Nonsense Mutation Dystrophinopathy |
| Milhem, Mohammed | Internal Medicine | Amgen, Inc. | A Phase 1b/2, Multicenter, Open-label Trial to Evaluate the Safety and Efficacy of Talimogene Laherparepvec and Ipilimumab Compared to Ipilimumab Alone in Subjects With Previously Untreated, Unresectable, Stage IIIb-IV Melanoma No.20110264 |
| Milhem, Mohammed | Internal Medicine | Celgene Corporation | A Phase I, Open-Label, Multicenter, Randomized, 2-Period, Crossover Study to Evaluate the Bioquivalence and Food Effect Bioavailability of CC-486 (Oral Azacitidine) Tablets in Adult Cancer Subjects |
| Nuangchamnong, Nina | Obstetrics & Gynecology | Washington University | Reproductive Scientist Development Program (RSDP) |
| Oral, Resmiye | Pediatrics | Iowa Department of Human Services | Trauma Informed Systems of Care in Iowa |
| Perlman, Stanley | Microbiology | National Institutes of Health | PPG: SARS-CoV-Host Cell Interactions and Vaccine Development |
| Philibert, Robert | Psychiatry | University of Georgia | Psychosocial Context and the Biological Clock: Changes in Weathering during Middle-Age |
| Polyak, Steven | Internal Medicine | Gilead Sciences, Inc. | A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Testicular Safety of Filgotinib in Adult Males with Moderately to Severely Active Ulcerative Colitis |
| Randak, Christoph | Pediatrics | National Institutes of Health | Probing adenylate kinase-dependent CFTR gating in vivo and as therapuetic target |
| Russell, Stephen | Ophthalmology & Visual Sciences | ProQR Therapeutics B.V. | ORA-ProQR QR-110 LCA clinical trial |
| Sabharwal, Rasnapreet | Internal Medicine | American Heart Association | Ang-(1-7) protects against stress-induced cardiac morbidity and mortality in muscular dystrophy |
| Santillan, Mark | Obstetrics & Gynecology | Washington University | RSDP Supplement Grant |
| Schultz, Michael | Radiology | ViewPoint Molecular Targeting, LLC | Production of Image-Guided Metastatic Melanoma Therapy Radiopharmaceuticals |
| Seo, Seongjin | Ophthalmology & Visual Sciences | National Institutes of Health | Retrograde intraflagellar transport in photoreceptors |
| Sharathkumar, Anjali Lentz, Steven Macfarlane, Donald |
Pediatrics | University of Texas Health Science Center at Houston | Regional Hemophilia Network Competing Continuation |
| Shy, Michael | Neurology | Acceleron Pharma, Inc. | A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ACE-083 in Patients with Charcot-Marie-Tooth Disease Types 1 and X |
| Spies, M. Ashley | Biochemistry | National Institutes of Health | Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase |
| Stapleton, Jack Houtman, Jon |
Internal Medicine | National Institutes of Health | The role of HCV RNA-targeted phosphatase PTPRE in T cell activation |
| Starner, Timothy | Pediatrics | Anthera Pharmaceuticals, Inc. | A Phase 3, Randomized, Open-Label, Assessor-Blind, Non-Inferiority, Active-Comparator Study Evaluating the Efficacy and Safety of Liprotamase in Subjects with Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency |
| Starner, Timothy | Pediatrics | Novartis Pharmaceuticals Corporation | A prospective observational study in cystic fibrosis patients with chronic respiratory Pseudomonas aeruginosa infection treated with TOBI PodhalerTM (tobramycin inhalation powder) or other FDA approved inhaled antipseudomonal antibacterial drugs |
| Stuart, Scott | Psychiatry | National Institutes of Health | Pragmatic Strategies for Assessing and Enhancing High Fidelity Delivery of Interpersonal Psychotherapy (IPT) in Community Practice |
| Thomas, Christie | Internal Medicine | Shire ViroPharma, Inc. | A randomized double-blind placebo-controlled study to evaluate the efficacy and safety of Cinryze (C1 esterase inhibitor [human]) for the treatment of acute antibody-mediated rejection in kidney transplant patients |
| Van Heukelom, Paul | Emergency Medicine | Cepheid | Nasal Swab and Nasopharyngeal Swab Specimen Collection for use with Xpert Xpress Flu and/ or Flu/ RSV Assays |
| Vaughan Sarrazin, Mary | Internal Medicine | US Department of Veterans Affairs | Contract Services to support Rural Health Resource Center |
| Vaughan Sarrazin, Mary | Internal Medicine | US Department of Veterans Affairs | Contract Services to support VISN 23 PACT Demo Lab |
| Vigil Gonzales, Carlos | Internal Medicine | Seattle Genetics, Inc. | A randomized, double-blind, placebo-controlled phase 2 study of vadastuximab talirine (SGN-CD33A) in combination with cytarabine and daunorubicin (7+3) induction chemotherapy in newly-diagnosed acute myeloid leukemia patients. |
| Wahls, Terry | Internal Medicine | US Department of Veterans Affairs | Center for the Prevention and Treatment of Visual Loss |
| Weiner, George | Cancer Center | National Institutes of Health | Lymphoma Specialized Program of Research Excellence (SPORE) in Human Cancer |
| Welsh, Michael | Internal Medicine | University of California, San Francisco | Pre Clinical and Clinical Development of a Novel Thiol-Saccharide Mucolytic |
| Wibbenmeyer, Lucy | Surgery | American Burn Association | Acute Burn ResUscitation Multicenter Prospective Observational Trial (ABRUPT) |
| Wilken, Jason | Physical Therapy | Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Improved Training Program for Fall Prevention of Warfighters with Lower Extremity Trauma (RAPID REHAB) |
| Zakharia, Yousef | Internal Medicine | X4 Pharmaceuticals, Inc. | A Phase 1/2 Trial of X4P-001 as Single Agent and in Combination with Axitinib in Patients with Advanced Renal Cell Carcinoma |
| Zhang, Jian | Pathology | American Heart Association | Regulation of Autoimmune Myocarditis by Protein Ubiquitination |
JULY 2017
| PI | Department | Sponsor | Proposal Title |
|---|---|---|---|
| Adams, Christopher | Internal Medicine | National Institutes of Health | Molecular pathogenesis of skeletal muscle atrophy |
| Ahern, Christopher | Molecular Physiology & Biophysics | Emily's Entourage | Therapeutic Correction of CFTR Nonsense Mutations |
| Anderson, Michael | Molecular Physiology & Biophysics | National Institutes of Health | Genetic dissection of pigmentary glaucoma |
| Attanasio, Massimo | Internal Medicine | National Institutes of Health | Role of GLIS2 in the Development of Cystic Kidney Disease |
| Bassuk, Alexander | Pediatrics | National Institutes of Health | Mechanistic studies on regenerative medicine approaches to childhood blindness |
| Bell, Edward | Pediatrics | Children's Hospital of Philadelphia | Post natal Growth and Retinopathy of Prematurity (G-ROP) Studies |
| Boes, Aaron | Pediatrics | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | Investigating the Neural Basis of Posterior Fossa Syndrome |
| Bonthius, Daniel | Pediatrics | National Institutes of Health | NO-mediated neuroprotection against alcohol: mechanism and potential therapy |
| Chimenti, Ruth | Physical Therapy | National Institutes of Health | Mechanism-based treatment approach to chronic tendinopathy pain |
| Comellas, Alejandro | Internal Medicine | Janssen Research and Development, LLC | A Study to Explore the Incidence of Influenza and RSV in Adults Hospitalized with Acute |
| Cui, Huxing | Pharmacology | National Institutes of Health | Behavioral characterization of humanized mouse model of eating disorder |
| Dixon, Bradley | Internal Medicine | PPD Investigator Services, LLC | Anemia Studies in CKD: Erythropoiesis via Novel PHI Daprodustat-in Incident Dialysis (ASCEND-ID) |
| Elcock, Adrian | Biochemistry | National Institutes of Health | Molecular Simulations of the Cell |
| Fingert, John | Ophthalmology & Visual Sciences | National Institutes of Health | TBK1-Related Glaucoma |
| Fingert, John Mullins, Robert |
Ophthalmology & Visual Sciences | National Institutes of Health | Molecular Genetics of Normal Tension Glaucoma |
| Flynn, Ryan | Radiation Oncology | Infondrian LLC | An Automated Patient Chart Error Detection System for Radiation Therapy |
| Furqan, Muhammad | Internal Medicine | Novartis Pharmaceuticals Corporation | A phase II, multicenter, three-cohort study of oral cMET inhibitor INC280 in adult patients with EGFR wild-type (wt), advanced non-small cell lung cancer (NSCLC) who have received one or two prior lines of systemic therapy for advanced/metastatic disease |
| Grumbach, Isabella | Internal Medicine | US Department of Veterans Affairs | Effect that CaMKII inhibition in vascular smooth muscle cells has on blood pressure |
| Imai, Yumi | Internal Medicine | National Institutes of Health | Role of lipid droplet protein in obesity and diabetes |
| Jennissen, Charles | Emergency Medicine | Iowa Department of Transportation | Increasing Public Awaremenss about the Dangers of Riding Off-Road Vehicles on the Road |
| Lee, Sangil | Emergency Medicine | Vanderbilt University | Guided-HF |
| Legge, Kevin | Pathology | National Institutes of Health | Chronic Alcohol Alteration of Influenza-Specific CD8 T cell Immunity and Protection |
| Levy, Barcey | Family Medicine | National Institutes of Health | Comparative Effectiveness of Fecal Immunochemical Tests with Optical Colonoscopy |
| Macfarlane, Donald | Internal Medicine | KaryopharmTherapeutics, Inc. | Phase 2b, Open-Label, Single-Arm Study of Selinexor Plus Low-Dose Dexamethasone in Patients with Multiple Myeloma Previously Treated with Lenalidomide, Pomalidomide, Bortezomib, Carfilzomib, and an anti-CD38 Monoclonal Antibody (mAb) and Refractory to Pri |
| Magnotta, Vincent Wemmie, John |
Radiology | National Institutes of Health | Characterization and Enhancement of Functional T1rho Imaging |
| Meier, Jeffery | Internal Medicine | Sanofi Pasteur, Inc. | Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection |
| Milhem, Mohammed | Internal Medicine | Oncolys BioPharma, Inc. | Open-label, Multi-center Phase IIa Study to Evaluate the Efficacy, Safety, and Immunological Response of OBP 301, Telomerase Specific Replication-competent Oncolytic Adenovirus in Patients with Unresectable Metastatic Melanoma |
| Miller, Delwyn | Psychiatry | Vanguard Research Group | A Study to Evaluate the Effect of ALKS 3831 Compared to Olanzapine on Body Weight in Young Adults with Schizophrenia, Schizophreniform, or Bipolar Disorder Who are Early in their Illness |
| Monga, Varun | Internal Medicine | Orbus Therapeutics, Inc. | A Phase 3, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress / Recur After Irradiation and Adjuvant Temozolomide Chemotherapy ( |
| Monga, Varun | Internal Medicine | Rising Tide Foundation for Clinical Cancer Research | Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b/2 trial |
| Nopoulos, Peggy | Psychiatry | National Institutes of Health | Longitudinal Assessment of Brain Structure and Function in Myotonic Dystrophy |
| Ohl, Michael | Internal Medicine | US Department of Veterans Affairs | Contract Services to support Rural Health Resource Center |
| Price, David | Biochemistry | George Washington University | A family of compounds that reactivate latent HIV without T cell activation |
| Rhodes, Troy | Internal Medicine | Boston Scientific Corporation | APPRAISE ATP |
| Richerson, George | Neurology | National Institutes of Health | Carver College of Medicine Clinical Neuroscientist Training Program (CNS-TP) |
| Richerson, George | Neurology | National Institutes of Health | Diversity Supplement, Parent grant, SUDEP Research Alliance: Respiratory and Arousal Mechanisms |
| Sharafuddin, Melhem | Surgery | Bolton Medical, Inc. | A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro in Subjects with an Acute, Complicated Type B Aortic Dissection |
| Sheffield, Val | Pediatrics | National Institutes of Health | Complex Mechanisms in Bardet-Biedl Syndrome Retinopathy |
| Sheffield, Val | Pediatrics | National Institutes of Health | Novel Glaucoma Treatment Using Genome Editing |
| Sinn, Patrick | Pediatrics | National Institutes of Health | A Hybrid Viral/Nonviral Vector for CFTR Delivery to CF Pig Airways |
| Sivitz, William | Internal Medicine | Case Western Reserve University | Epidemiology of Diabetes Interventions and Complications (EDIC) |
| Sohn, Elliott | Ophthalmology & Visual Sciences | National Institutes of Health | Choroidal Disease Mechanisms in AMD |
| Stone, Edwin | Ophthalmology & Visual Sciences | Dove Foundation | William J. Kimberling, Ph.D., Usher Research Laboratory |
| Stone, Edwin | Ophthalmology & Visual Sciences | National Philanthropic Trust | Glaucoma Excellence Fund |
| Tsalikian, Eva | Pediatrics | University of South Florida | Safety and Efficacy of Imatinib for Preseerving Beta-Cell Function in New Onset Type 1 Diabetes Mellitus |
| Varga, Steven | Microbiology | National Institutes of Health | Balancing protection versus immunopathology by RSV-specific memory CD8 T cells |
| Weiner, George | Cancer Center | National Institutes of Health | Cancer Center Support Grant (CCSG) |
| Winokur, Patricia | Internal Medicine | National Institutes of Health | VTEU FY2018, Task A, Option 1 |
| Winokur, Patricia | Internal Medicine | National Institutes of Health | 14-0107 Yellow Fever Vaccine - Task C - Option 3 |
| Winokur, Patricia | Internal Medicine | National Institutes of Health | VTEU Task Area A-D FY2017 - Option 2A Supplement |
| Wu, Jing | Pharmacology | American Heart Association | The Role of Endothelial Cullin3 in Vascular Function and Blood Pressure Regulation |
JUNE 2017
| PI | Department | Sponsor | Proposal Title |
|---|---|---|---|
| Ahmed, Azeemuddin | Emergency Medicine | Iowa Department of Public Health | Emergency Medical Services Medical Director Recruitment |
| Bollier, Matthew | Orthopaedics and Rehabilitation | Smith & Nephew Orthopaedics | Univ. of Iowa Orthopedic Sports Medicine Fellowship |
| Boudreau, Ryan | Internal Medicine | Roy J. Carver Charitable Trust | Systematic characterization of post-transcriptional gene regulatory networks in cardiac disease |
| Brown, Kyle | Internal Medicine | TARGET PharmaSolutions | A 5-year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepatitis |
| Buatti, John | Radiation Oncology | Galera Therapeutics, LLC | A phase 1, open-label, multi-center, dose escalation study of the safety, tolerability, pharmacodynamic and pharmacokinetic properties of intravenous GC4419 in combination with radiation and chemotherapy for squamous cell cancers of the head and neck |
| Buchanan, Gordon | Neurology | National Institutes of Health | Sleep state-dependent mechanisms of seizure-induced death |
| Coryell, William | Psychiatry | Janssen Research and Development, LLC | An Open-label, Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression |
| Davies, Brandon | Biochemistry | Wayne State University | An investigation of Angptl8's function, mechanism and therapeutic potential |
| Dhanesha, Nirav | Internal Medicine | American Heart Association | Mechanistic Role of Integrin 91 in Modulation of Arterial Thrombosis |
| Grumbach, Isabella | Internal Medicine | American Heart Association | CaMKII in mitochondria drives smooth muscle migration and neointimal hyperplasia |
| Hoffman, Eric | Radiology | Columbia University | Subclinical interstitial lung disease in MESA and FAR-ILD |
| Howard, Matthew | Neurosurgery | Johns Hopkins University | Targeted Neuroplasticity Training (TNT) |
| Ince, Mirac | Internal Medicine | US Department of Veterans Affairs | Determining which elements of the TH2 signaling pathway in BMT recipients are critical for intestinal immune conditioning |
| Jesudoss, Randhir | Internal Medicine | TARGET PharmaSolutions | A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis |
| Karandikar, Nitin | Pathology | Iowa City Veterans Affairs Medical Center | Immunotherapeutic Regulatory CD8 T Cells in Autoimmune Demyelinating Disease |
| Keith, Jerrod | Surgery | Allergan, Inc. | Breast Implant Follow-up Study: A Long-term Observational Study of the Safety of Allergan Silicone Gel-filled Breast Implants as Compared Both to Saline-filled Breast Implants and to National Norms |
| Kreder, Karl | Urology | National Institutes of Health | Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) |
| Kuehn, Markus | Ophthalmology & Visual Sciences | Boehringer Ingelheim Pharmaceuticals, Inc. | BI-Iowa Study: Neurotrophic factors in diabetic retinopathy |
| Kuehn, Markus | Ophthalmology & Visual Sciences | Glaucoma Research Foundation | GRF Shaffer Grant - A New Look at the Role of Microglia in Glaucoma |
| Langbehn, Douglas | Psychiatry | University College London | Improving function in huntington's disease through neurofeedback |
| Legge, Kevin Waldschmidt, Thomas |
Pathology | National Institutes of Health | Nanovaccine-Mediated Immune Protection Against Influenza Virus |
| Liu, Jing | Internal Medicine | American Heart Association | MicroRNA-204 in Aortic Aneurysmal Disease |
| London, Barry | Internal Medicine | Columbia University | Mitigation of Radiation Induced Damage to the Cardiac Conduction System by Mitochondrial Superoxide |
| Mathews, Katherine | Pediatrics | Italfarmaco S.p.A. | Randomised, double blind, placebo controlled, multicentre study to evaluate the efficacy and safety of givinostat in ambulant patients with Duchenne Muscular Dystrophy. |
| Mathews, Katherine | Pediatrics | Bristol-Myers Squibb Medical Imaging, Inc. | A Randomized, Double-Blind, Placebo-Controlled, Study to Assess the Efficacy, Safety, And Tolerability of BMS-986089 in Ambulatory Boys with Duchenne Muscular Dystrophy |
| Mathews, Katherine | Pediatrics | Pfizer, Inc. | A Multicenter, Open-Label Extension Study to Evaluate the Long Term Safety of PF-06252616 in Boys with Duchenne Muscular Dystrophy |
| Mazur, Alexander | Internal Medicine | BIOTRONIK | Plexa Regsitry |
| Meier, Jeffery | Internal Medicine | Chimerix, Inc. | The Chimerix CMX001 Registry A Prospective Observational Study for the Long-term Follow-up of Subjects Previously Enrolled in Selected Clinical Studies of CMX001 |
| Milhem, Mohammed | Internal Medicine | Checkmate Pharmaceuticals | A Multicenter, Open Label, Phase 1B Clinical Study of CMP-001 In Combination With Pembrolizumab In Subjects Who Have Been Treated With Pembrolizumab For Advanced Melanoma. |
| Miller, Benjamin | Orthopaedics and Rehabilitation | Orthopaedic Research & Education Foundation | Improving Multi-institutional Collaboration by Creating a Sarcoma Registry |
| Moye-Rowley, William | Molecular Physiology & Biophysics | University of Tennessee Health Science Center | Upc2A: A Central Regulator and Achilles' Heel of Fluconazole Resistance in Candida glabrata |
| Nopoulos, Peggy Wemmie, John |
Psychiatry | National Institutes of Health | The Iowa Neuroscience Specialty Program in Research Education (INSPIRE) |
| Parekh, Kalpaj | Cardiothoracic Surgery | University of Southern California | IPSC Stem Cell CFFT |
| Paulsen, Jane | Psychiatry | National Institutes of Health | Statistical disease modeling and clinimetrics to prepare for preventive trials in huntington disease |
| Perschbacher, Katherine | Pharmacology | American Heart Association, Midwest Affiliate | Molecular Mechanisms of RGS2 in Preeclampsia |
| Roller, Richard | Microbiology | National Institutes of Health | Regulation of budding during herpesvirus nuclear egress |
| Russo, Andrew | Molecular Physiology & Biophysics | US Department of Veterans Affairs | Photosensitivity as a preclinical assessment for treatment of post-traumatic headache |
| Sah, Rajan | Internal Medicine | American Heart Association | Ion channel regulation of pancreatic beta cell function |
| Sato, Mariko | Pediatrics | Children's Hospital of Philadelphia | COG: APEC14B1 Project Everychild |
| Segaloff, Deborah | Molecular Physiology & Biophysics | National Institutes of Health | A Mouse Model to Demonstrate the Impact of Myometrial FSHR on Fertility |
| Sharafuddin, Melhem | Surgery | Bolton Medical, Inc. | A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the Relay PRO Thoracic Stent-Graft in Subjects with Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers |
| Sheffield, Val | Pediatrics | Roy J. Carver Charitable Trust | The Science Behind Curing Heritable Blindness Research Programs of Excellence |
| Sheffield, Val | Pediatrics | Roy J. Carver Charitable Trust | Automated Retinal Differentiation Lab Instrumentation |
| Stevens, Hanna | Psychiatry | Roy J. Carver Charitable Trust | Neuropsychiatry Research Junior Research Programs of Excellence |
| Stone, Edwin | Ophthalmology & Visual Sciences | Usher 1F Collaborative, Inc. | |
| Stone, Edwin | Ophthalmology & Visual Sciences | Roy J. Carver Charitable Trust | The Science Behind Curing Heritable Blindness Research Programs of Excellence |
| Strack, Stefan | Pharmacology | Roy J. Carver Charitable Trust | Mitochondrial Dynamics and Calcium Cycling in Neuronal Injury, Excitably and Plasticity Research Program of Excellence |
| Sunderland, John | Radiology | University of California, San Francisco | Qualification and Harmonization of PET/MRI for Cancer Clinical Trials |
| Tanaka, Tomohiro | Internal Medicine | TARGET PharmaSolutions | A 5-year Longitudinal Observational Study of the Natural History and Management of Patients with Hepatocellular Carcinoma |
| Tomasson, Michael | Internal Medicine | Washington University | Center for Multiple Myeloma Nanotherapy, Project 3 |
| Tranel, Daniel | Neurology | California Institute of Technology | The Neurobiology of Social Decision-Making: Social Inference and Context |
| Tsalikian, Eva | Pediatrics | OPKO Biologics Ltd | A phase 3, open-label, randomized, multicenter, 12 months, efficacy and safety study of weekly MOD-4023 compared to daily Genotropin - therapy in pre-pubertal children with growth hormone deficiency. |
| Winokur, Patricia | Internal Medicine | National Institutes of Health | 15-0064 A/H5N8 Vaccine |
MAY 2017
| PI | Department | Sponsor | Proposal Title |
|---|---|---|---|
| Abel, E. Dale Norris, Andrew |
Internal Medicine | National Institutes of Health | Diabetes Research Training Program |
| Abel, Edwin | Molecular Physiology & Biophysics | Washington State University | Non-Neuronal Regulators of Sleep |
| Ahrens, Richard | Pediatrics | Quintiles, Inc. | A Multi-center, Randomized, Placebo-Controlled, Ascending Dose Phase I Study Designed to Assess the Safety, Tolerability, and Pharmacokinetics of PTI-428 in Subjects with Cystic Fibrosis |
| Allen, Bryan | Radiation Oncology | University of Texas Southwestern Medical Center | The STABLE-MATES Trial |
| Benson, Christopher | Internal Medicine | US Department of Veterans Affairs | Role of ASICs within sensory neurons in health and disease |
| Bishop, Gail | Microbiology | US Department of Veterans Affairs | VA IPA |
| Choi, Kent | Surgery | Atox Bio Ltd. | ATB-202: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Study Of AB103 As Compared To Placebo In Patients With Necrotizing Soft Tissue Infections (NSTI) |
| Comellas, Alejandro | Internal Medicine | Pearl Therapeutics, Inc. | A Randomized, Double-Blind, Parallel Group, Multi-Center Study to Assess the Efficacy and Safety of PT009 compared to PT005 on COPD Exacerbations over a 52-Week Treatment Period in Subjects With Moderate to Very Severe COPD |
| Cornell, Robert | Anatomy & Cell Biology | Marin Community Foundation | Preliminary analysis of zebrafish mutants with defects in embryonic development |
| Derdeyn, Colin | Radiology | Pulse Therapeutics, Inc. | Rapid Magnetomotive Thrombolysis for Stroke |
| Diekema, Daniel | Pathology | bioMerieux, Inc. | ADDENDUM to VITEK 2 and VITEK 2 Compact GP19 Antimicrobial Susceptibility Tests |
| Engelhardt, John | Anatomy & Cell Biology | Vertex Pharmaceuticals, Inc. | Vertex Pharmaceuticals / Agreement 2 / Amendment 3 |
| Femino, John | Orthopaedics and Rehabilitation | OMeGA Medical Grants Association | OMeGA Medical Grants Association Foot/Ankle Fellowship 2017-2018 |
| Fischer, Anthony | Pediatrics | National Institutes of Health | Initial Attachment of Bacteria to Mucus Strands in Cystic Fibrosis |
| Gantz, Bruce | Otolaryngology - Head & Neck Surgery | Iowa City Veterans Affairs Research Foundation | |
| Giangrande, Paloma | Internal Medicine | University of Missouri-Columbia | Database and software development for protein-nucleic acid structure prediction |
| Gildenberg, Melissa | Biochemistry | National Institutes of Health | Investigation of Rad5 Structure and Function in Error-Free Template Switching |
| Grose, Charles | Pediatrics | Iowa City Veterans Affairs Medical Center | Immunohistochemical Analysis for Herpes Zoster |
| Habelhah, Hasem | Pathology | National Institutes of Health | HtrA2-mediated RIP1 cleavage regulates neuronal inflammation and death |
| Horwitz, Phillip | Internal Medicine | St. Jude Medical, Inc. | Interventional Cardiology Fellowship Grant 2017-18 academic year |
| Janz, Siegfried | Pathology | University of California, Los Angeles | Regulation of c-myc translation by hnRNP A1: Role in multiple myeloma tumor responses |
| Kamholz, John | Neurology | Vaccinex, Inc. | A Phase 2, multi-center, randomized, double-blind, placebo controlled study in subjects with late prodromal and early manifest Huntington disease (HD) to assess the safety, tolerability, pharmacokinetics, and efficacy of VX15/2503 |
| Kamholz, John | Neurology | Huntington's Disease Society of America | HDSA Centers of Excellence |
| Karwal, Mark | Internal Medicine | Merck Sharp & Dohme Company | A Phase III Study of Pembrolizumab vs Best Supportive Care as Second-Line Therapy in Subjects with Previously Systemically Treated Advanced Hepatocellular Carcinoma (KEYNOTE 240). |
| Karwal, Mark | Internal Medicine | NSABP Foundation, Inc. | NSABP PROTOCOL B-57-I/PALLAS |
| Kline, Joel | Internal Medicine | GlaxoSmithKline LLC | Post-authorisation Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events in COPD Patients Using Inhaled UMEC/VI Combination or Inhaled UMEC versus Tiotropium (Study 2 |
| Krasowski, Matthew | Pathology | Roche Diagnostics Corporation | Performance Evaluation of Elecsys Anti-HBe Immunoassay and PreciControl Anti-HBe on cobas e 602 Analyzer |
| Leone, Jose | Internal Medicine | Merck Sharp & Dohme Company | A Phase III, Randomized, Double-blind Study to Evaluate Pembrolizumab Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy for Triple Negative Breast Cancer |
| Mathews, Katherine | Pediatrics | Muscular Dystrophy Association | MDA Care Center |
| Mathews, Katherine | Pediatrics | Santhera Pharmaceuticals (Switzerland) Ltd | A Phase III Double Blind , Randomized, Placebo-controlled study assessing the efficacy, safety and tolerability of idebenone in pati ents with Duchenne Muscular Dsytrophy receiving Glucocorticoid Steriods. SIDEROS |
| Mazur, Alexander | Internal Medicine | University of Rochester | JAVA CRT |
| Michaelson, Jacob | Psychiatry | Simons Foundation | SPARK recruitment center in Iowa |
| Miller, Delwyn | Psychiatry | University of Southern California | Long-Term Nicotine Treatment of Mild Cognitive Impairment |
| Moore, Steven | Pathology | Sarepta Therapeutics | SOW 7 - New Statement of Work |
| Narayanan, Nandakumar | Neurology | Roy J. Carver Charitable Trust | Neuromodulation Research Program of Excellence |
| Santillan, Donna Santillan, Mark Grobe, Justin |
Obstetrics & Gynecology | Carmentix Pte Ltd. | Estimating copeptin in urine during the first trimester of pregnancy |
| Seering, Melinda | Anesthesia | General Electric Healthcare | Multi-site Anesthesia randomized controlled STudy of End tidal control (Et Control) compared to conventional anesthesia Results (MASTER-Anesthesia Trial) |
| Sharathkumar, Anjali | Pediatrics | Johns Hopkins University | Prospective Multi-Center Evaluation of the Duration of Therapy for Thrombosis in Children (the Kids-DOTT Trial) |
| Snyder, Peter | Internal Medicine | US Department of Veterans Affairs | Epithelial Sodium Channel Trafficking |
| Stapleton, Jack | Internal Medicine | Iowa Department of Public Health | HIV Core Medical and Support Services |
| Stevens, Hanna | Psychiatry | Nellie Ball Trust | Early Neurodevelopmental Mechanisms in Schizophrenia |
| Stoltz, David Welsh, Michael |
Internal Medicine | University of Washington, Seattle | Combined Effects of Ivacaftor and Antibiotics Study - Ancillary Stuies |
| Stoltz, David Zabner, Joseph |
Internal Medicine | National Institutes of Health | Airway Alkalinization and Repurposing Tromethamine as a Therapeutic Approach in Cystic Fibrosis |
| Strack, Stefan | Pharmacology | National Institutes of Health | Predoctoral Training in the Pharmacological Sciences |
| Strack, Stefan | Pharmacology | National Institutes of Health | PP2A in Neurodevelopmental Disorders |
| Strathearn, Lane | Pediatrics | National Institutes of Health | Oxytocin and Brain Reward and Stress Responses to Infant Cues in Addicted Mothers |
| Tarini, Beth | Pediatrics | Genetic Alliance | NBS Clearinghouse- Genetics Alliance |
| Tsalikian, Eva | Pediatrics | Ascendis Pharma A/S | A multicenter, Phase 3, randomized, open-label, active-controlled, parallel-group trial investigating the safety, tolerability, and efficacy of TransCon hGH administered once a week versus standard daily hGH replacement therapy over 52 weeks in prepuberta |
| Uc, Aliye | Pediatrics | University of Texas, MD Anderson Cancer Center | Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer |
| Vaughan Sarrazin, Mary | Internal Medicine | US Department of Veterans Affairs | Contract Services to support Rural Health Resource Center |
| Wessel, Jan | Neurology | Roy J. Carver Charitable Trust | Neuropsychiatric Diseases Junior Research Programs of Excellence |
| Winokur, Patricia | Internal Medicine | National Institutes of Health | VTEU Task Area A-D FY2017 |
| Young, Samuel | Anatomy & Cell Biology | National Institutes of Health | Regulation of Synaptic Vesicle Dynamics in the Auditory System |