Who would request this test?
   Pediatric and adult endocrinologists, neurosurgeons, neonatologists

How to order the test?
   Contact Client Services - 866-844-2522 or
   Refer to the Insulin-Like Growth Factor I test entry in the UIDL Test Directory

Insulin-like growth factor I (IGF-1) measurements are used to assess growth hormone (GH) deficiency or excess. Serum IGF-1 concentrations below the 2.5th percentile are consistent with GH deficiency or severe GH resistance.  IGF-1 is also monitored during GH replacement therapy in children and adults, with the therapeutic aim to achieve IGF-1 concentrations within the age- and sex-appropriate reference range.  Elevated IGF-1 concentrations help support diagnosis of acromegaly in conjunction with compatible clinical signs and symptoms.  IGF-1 measurements are reported both as a concentration with age/gender-specific reference ranges and with Z-scores.

See also Growth Hormone