Brad A. Amendt, PhD
- microRNA gene therapies for tissue engineering
- Development of 3D printed scaffolds and gene therapies for cleft palate repair
- Bone and tissue regeneration using new microRNA biotechnologies
Botand Banfi, MD, PhD
- Molecular mechanisms that underlying defects in cystic fibrosis and deafness, with a focus on ROS and NADPH oxidase
Adam Dupuy, PhD
- Use of sleeping beauty transposon system to generate tissue specific-models of cancer in mice
John F. Engelhardt, PhD
- Development of gene therapies for inherited and environmentally induced diseases
- Development of recombinant adeno-associated viral vectors for gene therapy
- Investigation of the pathogenesis and treatment of cystic fibrosis lung disease
- Mechanisms underlying ischemia/reperfusion injury and applications of gene therapy in the liver
C. Andrew Frank, PhD
- Use of Drosophila genetics and pharmacology to understand signaling pathways that link synaptic instability to disorders of the nervous system
Tom Rutkowski, PhD
- Mechanistic links between endoplasmic reticulum homeostasis and lipid metabolism in the liver
- Mechanisms whereby dysregulation of the ER stress response contributes to diseases of liver function (metabolic syndrome, hepatitis, alcohol steatosis)
Ling Yang, PhD
- . Cellular and molecular mechanisms of Nonalcoholic fatty liver disease (NAFLD);
- . Organelle function in the context of obesity and diabetes;
- . The role of organelle stress responses in maintaining Immuno-metabolic homeostasis in cardiovascular diseases (CVDs)
Charles Yeaman, PhD
- Molecular mechanisms underlying renal cystogenesis, with a focus on dysfunction of the primary cilia
Sam M. Young, Jr. PhD
- Development of gene therapies for hearing restoration/preservation
- Development of gene therapies to treat neurodegeneration
- Development of Adenoviral vectors for gene therapy applications
- Development of gene therapies to treat ataxia