Eric S. Van Otterloo, PhD
Associate Professor
Introduction
Dr. Van Otterloo joined the University of Iowa College of Dentistry in 2019 as an assistant professor in the Department of Periodontics. He was a Postdoctoral Fellow and Research Associate from 2012-2019 in the Department of Craniofacial Biology at the University of Colorado, School of Dental Medicine, before transitioning to UI.
Current Positions
- Associate Professor of Periodontics
- Associate Professor of Iowa Institute for Oral Health
- Associate Professor of Anatomy and Cell Biology
Education
- PhD in Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa
- BA in Biology, Dordt University, Sioux Center, Iowa
- Postdoctoral Research Fellow in Craniofacial and Developmental Biology, University of Colorado - Denver, Aurora, Colorado
Graduate Program Affiliations
Selected Publications
- Shao F, Van Otterloo E, Cao H. Computational identification of key transcription factors for embryonic and postnatal Sox2+ dental epithelial stem cell. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573158. doi: 10.1101/2023.12.22.573158. PMID: 38187542; PMCID: PMC10769342.
- Petrin AL, Machado-Paula LA, Hinkle A, Hovey L, Awotoye W, Chimenti M, Darbro B, Ribeiro-Bicudo LA, Dabdoub SM, Peter T, Breheny P, Murray JC, Van Otterloo E, Rengasamy Venugopalan S, Moreno-Uribe LM. Familial Oculoauriculovertebral Spectrum: A Genomic Investigation of Autosomal Dominant Inheritance. Cleft Palate Craniofac J. 2025 Jan 17:10556656241306202. doi: 10.1177/10556656241306202. Epub ahead of print. PMID: 39819101.
- Kenny C, Dilshat R, Seberg HE, Van Otterloo E, Bonde G, Helverson A, Franke CM, Steingrímsson E, Cornell RA. TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes. PLoS Genet. 2022 May 17;18(5):e1010207. doi: 10.1371/journal.pgen.1010207. Erratum in: PLoS Genet. 2022 Aug 29;18(8):e1010378. doi: 10.1371/journal.pgen.1010378. PMID: 35580127; PMCID: PMC9159589.
- Van Otterloo, E., Milanda, I., Pike, H., Thompson, J. A., Li, H., Jones, K. L. & Williams, T. (2022). AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development. eLife 11. DOI: 10.7554/eLife.70511. PMID: 35333176. PMCID: PMC9038197.
- Woodruff, E. D., Gutierrez, G. C., Van Otterloo, E., Williams, T. & Cohn, M. J. (2021). Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Developmental biology 472 67-74. DOI: 10.1016/j.ydbio.2020.12.017. PMID: 33460639. PMCID: PMC8018193.
- Rengasamy Venugopalan, S. & Van Otterloo, E. (2021). The Skull's Girder: A Brief Review of the Cranial Base. Journal of developmental biology 9 (1). DOI: 10.3390/jdb9010003. PMID: 33498686. PMCID: PMC7838769.
- Schotanus, M. D. & Van Otterloo, E. (2020). Finding MEMO-Emerging Evidence for MEMO1's Function in Development and Disease. Genes 11 (11). DOI: 10.3390/genes11111316. PMID: 33172038. PMCID: PMC7694686.
- Jereb, S., Hwang, H. W., Van Otterloo, E., Govek, E. E., Fak, J. J., Yuan, Y., Hatten, M. E. & Darnell, R. B. (2018). Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types. eLife 7. DOI: 10.7554/eLife.34042. PMID: 29578408. PMCID: PMC5898910.
- Van Otterloo, E., Li, H., Jones, K. L. & Williams, T. (2018). AP-2α and AP-2β cooperatively orchestrate homeobox gene expression during branchial arch patterning. Development (Cambridge, England) 145 (2). DOI: 10.1242/dev.157438. PMID: 29229773. PMCID: PMC5825845.
- Seberg, H. E., Van Otterloo, E. & Cornell, R. A. (2017). Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma. Pigment cell & melanoma research 30 (5) 454-466. DOI: 10.1111/pcmr.12611. PMID: 28649789. PMCID: PMC5939569.