Kalpaj R. Parekh, MBBS
Professor, Department of Cardiothoracic Surgery
Primary Office
Staff Contact
Introduction
Chronic Rejection in Lung Transplantation
My research focus is on the development of Obliterative bronchiolitis in the lung transplant patients. Currently my laboratory is investigating the role of epithelial stem cells in the development of this progressively fatal condition in lung transplant patients.
Current Positions
- Departmental Executive Officer and Chair, Department of Cardiothoracic Surgery
- Professor of Cardiothoracic Surgery
- Professor of Anatomy and Cell Biology
- Surgical Director of Lung Transplant Program, Department of Cardiothoracic Surgery
- Nicholas P. Rossi Professor in Cardiothoracic Surgery, Department of Cardiothoracic Surgery
Education
- MBBS, Seth G.S. Medical College, University of Mumbai, Mumbai, India
- Fellow in Research, Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, United States
- Resident in Categorical General Surgery, Lenox Hill Hospital, New York, New York, United States
- Fellow in Research, Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri, United States
- Fellow in Lung Transplant, Washington University School of Medicine, St. Louis, Missouri, United States
- Fellow in General Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, United States
- Resident in Cardiothoracic Surgery, University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States
Graduate Program Affiliations
Center, Program and Institute Affiliations
Research Interests
- Development of an animal model for chronic rejection and cystic fibrosis in lung transplantation
- Role of Epithelial Stem Cells in Lung Transplantation
- Determining optimal timing of Esophagectomy following completion of Neoadjuvant therapy
- Chronic Rejection in Lung Transplantation
Licenses & Certifications
- American Board of Thoracic Surgery, American Board of Thoracic Surgery
- UNOS Certified (Lung Transplant).
- Iowa Medical License, Iowa Board of Medicine, Iowa
- Board Certified, American Board of Surgery, American Board of Surgery
- ECFMG certification, ECFMG
- Certified (Lung Transplant), UNOS
Selected Publications
- Iannettoni, M.D., Lynch, W.R., Parekh, K.R., and McLaughlin, K.A. 2011. Kaizen method for esophagectomy patients: improved quality control, outcomes, and decreased costs. The Annals of thoracic surgery 91:1011-1017; discussion 1017-1018. PMID: 21292238 DOI: 10.1016/j.athoracsur.2011.01.001
- Van Natta, T.L., Parekh, K.R., Dearmond, D.T., and Iannettoni, M.D. 2010. Damage control: cavoatrial anastomosis during a catastrophic right intrapericardial pneumonectomy. Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 37:587-590. PMID: 20978577 PMCID: PMC2953238
- Excoffon, K.J., Gansemer, N.D., Mobily, M.E., Karp, P.H., Parekh, K.R., and Zabner, J. 2010. Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia. PloS one 5:e9909. PMID: 20361046 PMCID: PMC2845650 DOI: 10.1371/journal.pone.0009909
- Gerke, H., Siddiqui, J., Parekh, K.R., Vanderheyden, A.D., and Mitros, F.A. 2009. Esophageal perforation complicating band ligator-assisted mucosal resection. Gastrointestinal endoscopy 69:153-154; discussion 154. PMID: 18951128 DOI: 10.1016/j.gie.2008.06.020
- Van Natta, T.L., Parekh, K.R., Reed, C.G., Shebrain, S.A., and Omari, B.O. 2008. Benign esophagobronchial fistula with and without esophageal obstruction: two ends of the surgical spectrum. The Annals of thoracic surgery 85:322-325. PMID: 18154838 DOI: 10.1016/j.athoracsur.2007.07.069
- Parekh, K.R., Adusumilli, P.S., and Patterson, G.A. 2008. Lung transplantation in India: a possible treatment option. The National medical journal of India 21:228-233. PMID: 19320322
- Clamon, G.H., and Parekh, K.R. 2008. Mortality related to neoadjuvant therapy and surgery for stage III non-small-cell lung cancer. Clinical lung cancer 9:213-216. PMID: 18650168 DOI: 10.3816/CLC.2008.n.031
- Parekh, K., and Iannettoni, M.D. 2007. Complications of esophageal resection and reconstruction. Seminars in thoracic and cardiovascular surgery 19:79-88. PMID: 17403462 DOI: 10.1053/j.semtcvs.2006.11.002
- Parekh, K., Ramachandran, S., Cooper, J., Bigner, D., Patterson, A., and Mohanakumar, T. 2005. Tenascin-C, over expressed in lung cancer down regulates effector functions of tumor infiltrating lymphocytes. Lung cancer 47:17-29. PMID: 15603851 DOI: 10.1016/j.lungcan.2004.05.016
- Parekh, K., Meyers, B.F., Patterson, G.A., Guthrie, T.J., Trulock, E.P., Damiano, R.J., Jr., and Moazami, N. 2005. Outcome of lung transplantation for patients requiring concomitant cardiac surgery. The Journal of thoracic and cardiovascular surgery 130:859-863. PMID: 16153940 DOI: 10.1016/j.jtcvs.2005.05.004