– Newly Added Paper

October 31

• Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses.  Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge SK, Song RJ, et al…..Wallace RB, Emerging Risk Factors Collaboration/EPIC-CVD/Million Veteran Program. Circulation. 2022 Oct 31. doi: 10.1161/CIRCULATIONAHA.122.060700. PMID: 36314129 

October 25

• Effects of Combined Inorganic Nitrate and Nitrite Supplementation on Cardiorespiratory Fitness and Skeletal Muscle Oxidative Capacity in Type 2 Diabetes: A Pilot Randomized Controlled Trial. Turner KD, Kronemberger A, Bae D, Bock, JM, Hughes WE, Ueda K, Feider AJ, Hanada S, de Sousa LGO, Harris, MP, Anderson EJ, Bodine SC, Zimmerman MB, Casey DP, Lira VA. Nutrients. 2022 Oct 25;14(21):4479. doi: 10.3390/nu14214479. PMID: 36364742
• Elucidating the role of Rgs2 expression in the PVN for metabolic homeostasis in mice.  Deng Y, Dickey JE, Saito K, Deng G, Singh U, Jiang J, Toth BA, Zhu Z, Zingman LV, Resch JM, Grobe JL, Cui H. Mol Metab. 2022 Oct 25:101622. doi: 10.1016/j.molmet.2022.101622. PMID: 36307046 

October 24

• PRC2 loss drives MPNST metastasis and matrix remodeling.  Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. JCI Insight. 2022 Oct 24;7(20):e157502. doi: 10.1172/jci.insight.157502. PMID: 36066973 

October 23

• Hypomorphism of a Novel Long ERα Isoform Causes Severe Reproductive Dysfunctions in Female Mice. Saito K, Dickey JE, Rodeghiero SR, Toth BA, Kelly MJ, Deng Y, Singh U, Deng G, Jiang J, Cui H. Endocrinology. 2022 Oct 23;163(12):bqac160. doi: 10.1210/endocr/bqac160. PMID: 36181426

October 21

• Development and Characterization of a New Monoclonal Antibody against SARS-CoV-2 NSP12.  Meng W, Guo S, Cao S, Shuda M, Robinson-McCarthy LR, McCarthy KR, Shuda Y, Paniz Mondolfi AE, Bryce C, Grimes Z, Sordillo EM, Cordon-Cardo C, Li P, Zhang H, Perlman S, Guo H, Gao SJ, Chang Y, Moore PS. J Med Virol. 2022 Oct 21. doi: 10.1002/jmv.28246. PMID: 36271490
• Introduction to Special Collection Issue Interdisciplinary Aging Research to Address Health Disparities in Alzheimer's Disease and Related Dementias: A Scientific Training Program for Early-Career Scholars.  Aranda MP, Wallace RB. J Gerontol B Psychol Sci Soc Sci. 2022 Oct 21:gbac170. doi: 10.1093/geronb/gbac170. PMID: 36268780
• Plasticity of Cerebral Microvascular Structure and Mechanics During Hypertension and Following Recovery of Arterial Pressure.  Sabharwal R, Chapleau MW, Gerhold TD, Baumbach GL, Faraci FM. Am J Physiol Heart Circ Physiol. 2022 Oct 21. doi: 10.1152/ajpheart.00292.2022. PMID: 36269650
• SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas.  Zhu EY, Riordan JD, Vanneste M, Henry MD, Stipp CS, Dupuy AJ. NPJ Precis Oncol. 2022 Oct 21;6(1):74. doi: 10.1038/s41698-022-00310-7. PMID: 36271142

October 20

• Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart.  Riehle C, Weatherford ET, McCarty NS, Seei A, Jaishy BP, Manivel R, Galuppo P, Allamargot C, Hameed T, Boudreau RL, Bauersachs J, Weiss RM, Abel ED. Mol Cell Biol. 2022 Oct 20;42(10):e0016322. doi: 10.1128/mcb.00163-22. PMID: 36125265

October 19

• Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice.  Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL. Hypertension. 2022 Oct 19. doi: 10.1161/HYPERTENSIONAHA.122.20169. PMID: 36259376
• Metabolic clearance of oxaloacetate and mitochondrial complex II respiration: Divergent control in skeletal muscle and brown adipose tissue.  Yu L, Fink BD, Som R, Rauckhorst AJ, Taylor EB, Sivitz WI. Biochim Biophys Acta Bioenerg. 2022 Oct 19:148930. doi: 10.1016/j.bbabio.2022.148930. PMID: 36272463

October 18

• Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: A Systematic Review and Network Meta-analysis of Randomized Trials.  Snetselaar L, Cheek JJ, Fox SS, Healy HS, Schweizer ML, Bao W, Kamholz J, Titcomb TJ. Neurology. 2022 Oct 18:10.1212/WNL.0000000000201371. doi: 10.1212/WNL.0000000000201371. PMID: 36257717
• Pandemic origins and a One Health approach to preparedness and prevention: Solutions based on SARS-CoV-2 and other RNA viruses.  Keusch GT, Amuasi JH, Anderson DE, Daszak P, Eckerle I, Field H, Koopmans M, Lam SK, Das Neves CG, Peiris M, Perlman S, Wacharapluesadee S, Yadana S, Saif L. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2202871119. doi: 10.1073/pnas.2202871119. PMID: 36215506. Review.

October 17

• CT-derived vessel segmentation for analysis of post-radiation therapy changes in vasculature and perfusion. Wuschner AE, Flakus MJ, Wallat EM, Reinhardt JM, Shanmuganayagam D, Christensen GE, Gerard SE, Bayouth JE. Front Physiol. 2022 Oct 17;13:1008526. doi: 10.3389/fphys.2022.1008526. PMID: 36324304 

October 15

• Intoxicating effects of alcohol depend on acid-sensing ion channels.  Harmata GIS, Chan AC, Merfeld MJ, Taugher-Hebl RJ, Harijan AK, Hardie JB, Fan R, Long JD, Wang GZ, Dlouhy BJ, Bera AK, Narayanan NS, Wemmie JA. Neuropsychopharmacology. 2022 Oct 15. doi: 10.1038/s41386-022-01473-4. PMID: 36243771

October 14

• The Tumor Suppressor Protein TRAF3 Modulates GSK3 Activity and Susceptibility of B Lymphoma Cells to GSK3 Inhibition.  Hornick EL, Stunz LL, Sabree S, Wu X, Witzig TE, Bishop GA. Cancers (Basel). 2022 Oct 14;14(20):5029. doi: 10.3390/cancers14205029. PMID: 36291813

October 13

• Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism.  Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. JCI Insight. 2022 Oct 13:e159419. doi: 10.1172/jci.insight.159419. PMID: 36227698
• Brain Interleukin-17A contributes to neuroinflammation and cardiac dysfunction in rats with myocardial infarction.  Yu Y, Weiss RM, Wei SG. Front Neurosci. 2022 Oct 13;16:1032434. doi: 10.3389/fnins.2022.1032434. eCollection 2022. PMID: 36312009
• Involvement of the cerebellum in migraine.  Wang M, Tutt JO, Dorricott NO, Parker KL, Russo AF, Sowers LP. Front Syst Neurosci. 2022 Oct 13;16:984406. doi: 10.3389/fnsys.2022.984406. eCollection 2022. PMID: 36313527

October 12

• A saturated map of common genetic variants associated with human height.  Yengo L, London B, et al, 23andMe Research Team; VA Million Veteran Program; DiscovEHR (DiscovEHR and MyCode Community Health Initiative); eMERGE (Electronic Medical Records and Genomics Network); Lifelines Cohort Study; PRACTICAL Consortium; Understanding Society Scientific Group, Chasman DI, Cho YS, Heid IM, McCarthy MI, Ng MCY, O'Donnell CJ, Rivadeneira F, Thorsteinsdottir U, Sun YV, Tai ES, Boehnke M, Deloukas P, Justice AE, Lindgren CM, Loos RJF, Mohlke KL, North KE, Stefansson K, Walters RG, Winkler TW, Young KL, Loh PR, Yang J, Esko T, Assimes TL, Auton A, Abecasis GR, Willer CJ, Locke AE, Berndt SI, Lettre G, Frayling TM, Okada Y, Wood AR, Visscher PM, Hirschhorn JN. Nature. 2022 Oct 12. doi: 10.1038/s41586-022-05275-y. PMID: 36224396

October 11

• Contrastive learning and subtyping of post-COVID-19 lung computed tomography images. Li F, Zhang X, Comellas AP, Hoffman EA, Yang T, Lin CL. Front Physiol. 2022 Oct 11;13:999263. doi: 10.3389/fphys.2022.999263. eCollection 2022. PMID: 36304574
• A Task-Specific Algorithm to Estimate Occupational (1→3)-β-D-glucan Exposure for Farmers in the Biomarkers of Exposure and Effect in Agriculture Study.  Friesen MC, Hung F, Xie S, Viet SM, Deziel NC, Locke SJ, Josse PR, Sauvé JF, Andreotti G, Thorne PS, Beane-Freeman LE, Hofmann JN. Ann Work Expo Health. 2022 Oct 11;66(8):974-984. doi: 10.1093/annweh/wxac041. PMID: 35731645

October 10

• Manipulation of Redox Metabolism using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-sensitization by ATM Inhibitors in Colorectal Cancer.  Callaghan CM, Abukhiran IM, Masaadeh A, Van Rheeden RV, Kalen AL, Rodman SN 3rd, Petronek MS, Mapuskar KA, George BN, Coleman MC, Goswami PC, Allen BG, Spitz DR, Caster JM. Int J Radiat Oncol Biol Phys. 2022 Oct 10:S0360-3016(22)03438-1. doi: 10.1016/j.ijrobp.2022.10.012. PMID: 36228747
• A Matched Survival Analysis of Lung Transplant Recipients with Covid-19-related Respiratory Failure. Freischlag K, Lynch TJ, Ievlev V, Gries C, Keech JC, Arshava EV, Pena T, Klesney-Tait JA, Parekh KR. Ann Thorac Surg. 2022 Oct 10:S0003-4975(22)01314-5. doi: 10.1016/j.athoracsur.2022.09.039. PMID: 36228676

October 7

• Autonomic changes in Huntington's disease correlate with altered central autonomic network connectivity. Schultz JL, Heinzerling AE, Brinker AN, Harshman LA, Magnotta VA, Kamholz JA, Boes AD, Nopoulos PC. Brain Commun. 2022 Oct 7;4(5):fcac253. doi: 10.1093/braincomms/fcac253. PMID: 36324870 
• Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic Neuritis. Godwin CR, Anders JJ, Cheng L, Elwood BW, Kardon RH, Gramlich OW. Biomolecules. 2022 Oct 7;12(10):1437. doi: 10.3390/biom12101437. PMID: 36291646

October 4

• CT-based lung motion differences in patients with usual interstitial pneumonia and nonspecific interstitial pneumonia.  Choi J, Chae KJ, Jin GY, Lin CL, Laroia AT, Hoffman EA, Lee CH. Front Physiol. 2022 Oct 4;13:867473. doi: 10.3389/fphys.2022.867473. eCollection 2022. PMID: 36267579
• Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program (SARP). Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, Erzurum SC, Lempel J, Moore W, Bleecker E, Phillips BR, Mauger DT, Hoffman EA, Fain SB, Reeder SB, Sorkness RL, Jarjour NN, Denlinger LC, Schiebler ML. Am J Respir Crit Care Med. 2022 Oct 4. doi: 10.1164/rccm.202203-0597OC. PMID: 36194556

October 1

• A computed tomography imaging-based subject-specific whole-lung deposition model.  Zhang X, Li F, Rajaraman PK, Choi J, Comellas AP, Hoffman EA, Smith BM, Lin CL. Eur J Pharm Sci. 2022 Oct 1;177:106272. doi: 10.1016/j.ejps.2022.106272. PMID: 35908637
• Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity-related cancer risk and mortality in Black and Latina Women's Health Initiative participants.  Pichardo MS, Esserman D, Ferrucci LM, Molina Y, Chlebowski RT, Pan K, Garcia DO, Lane DS, Shadyab AH, Lopez-Pentecost M, Luo J, Kato I, Springfield S, Rosal MC, Bea JW, Cespedes Feliciano EM, Qi L, Nassir R, Snetselaar L, Manson J, Bird C, Irwin ML. Cancer. 2022 Oct;128(20):3630-3640. doi: 10.1002/cncr.34428. PMID: 35996861
• ASO Visual Abstract: Analysis of Breast Cancer Patients' Understanding and Worry About Lymphedema. Uhlmann RA, Mott SL, Curry M, Phadke S, Sugg SL, Erdahl LM, Weigel RJ, Lizarraga IM. Ann Surg Oncol. 2022 Oct;29(10):6438-6439. doi: 10.1245/s10434-022-12244-2. PMID: 35960453
• Association of low serum albumin with venous thrombosis in pediatric patients.  Bhasin N, Roe DJ, Saboda K, Journeycake J, Moreno V, Lentz SR. Thromb Res. 2022 Oct;218:48-51. doi: 10.1016/j.thromres.2022.08.008. PMID: 35988444
• Associations of coffee/caffeine consumption with postmenopausal breast cancer risk and their interactions with postmenopausal hormone use.  Yaghjyan L, McLaughlin E, Lehman A, Neuhouser ML, Rohan T, Lane DS, Snetselaar L, Paskett E. Eur J Nutr. 2022 Oct;61(7):3449-3459. doi: 10.1007/s00394-022-02899-8. PMID: 35583696
• Characterization of sub-pollen particles in size-resolved atmospheric aerosol using chemical tracers.  Mampage CBA, Hughes DD, Jones LM, Metwali N, Thorne PS, Stone EA. Atmos Environ X. 2022 Oct;15:100177. doi: 10.1016/j.aeaoa.2022.100177. PMID: 36186266
• Ferret Lung Transplantation Models Differential Lymphoid Aggregate Morphology Between Restrictive and Obstructive Forms of Chronic Lung Allograft Dysfunction.  Lynch TJ, Ahlers BA, Swatek AM, Ievlev V, Pai AC, Brooks L, Tang Y, Evans IA, Meyerholz DK, Engelhardt JF, Parekh KR. Transplantation. 2022 Oct 1;106(10):1974-1989. doi: 10.1097/TP.0000000000004148. PMID: 35442232
• Fibrous Cap Thickness Predicts Stable Coronary Plaque Progression: Early Clinical Validation of a Semiautomated OCT Technology. Kassis N, Kovarnik T, Chen Z, Weber JR, Martin B, Darki A, Woo V, Wahle A, Sonka M, Lopez JJ. J Soc Cardiovasc Angiogr Interv. 2022 Sep-Oct;1(5):100400. doi: 10.1016/j.jscai.2022.100400. PMID: 36397766 
• FXYD3 facilitates Na⁺ and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase. Cano Portillo C, Villacreses R, Thurman AL, Pezzulo AA, Zabner J, Thornell IM. Am J Physiol Cell Physiol. 2022 Oct 1;323(4):C1044-C1051. doi: 10.1152/ajpcell.00047.2022. PMID: 35993520
• Hypomorphism of a novel long ERα isoform causes severe reproductive dysfunctions in female mice.  Saito K, Dickey JE, Rodeghiero SR, Toth BA, Kelly MJ, Deng Y, Singh U, Deng G, Jiang J, Cui H. Endocrinology. 2022 Oct 1:bqac160. doi: 10.1210/endocr/bqac160. PMID: 36181426
• NMR resonance assignments of the DNA binding domain of mouse Junctophilin-2.  Yu L, Hall DD, Zhao W, Song LS. Biomol NMR Assign. 2022 Oct;16(2):273-279. doi: 10.1007/s12104-022-10091-6. PMID: 35665900
• Pharmacological FGF21 signals to glutamatergic neurons to enhance leptin action and lower body weight during obesity.  Claflin KE, Sullivan AI, Naber MC, Flippo KH, Morgan DA, Neff TJ, Jensen-Cody SO, Zhu Z, Zingman LV, Rahmouni K, Potthoff MJ. Mol Metab. 2022 Oct;64:101564. doi: 10.1016/j.molmet.2022.101564. PMID: 35944896
• Proactive esophageal cooling protects against thermal insults during high-power short-duration radiofrequency cardiac ablation.  Mercado Montoya M, Gomez Bustamante T, Berjano E, Mickelsen SR, Daniels JD, Hernandez Arango P, Schieber J, Kulstad E. Int J Hyperthermia. 2022;39(1):1202-1212. doi: 10.1080/02656736.2022.2121860. PMID: 36104029
• Quantification of lung ventilation defects on hyperpolarized MRI: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD study.  Zhang X, Angelini ED, Haghpanah FS, Laine AF, Sun Y, Hiura GT, Dashnaw SM, Prince MR, Hoffman EA, Ambale-Venkatesh B, Lima JA, Wild JM, Hughes EW, Barr RG, Shen W. Magn Reson Imaging. 2022 Oct;92:140-149. doi: 10.1016/j.mri.2022.06.016. PMID: 35777684
• RBD-mRNA vaccine induces broadly neutralizing antibodies against Omicron and multiple other variants and protects mice from SARS-CoV-2 challenge.  Shi J, Zheng J, Zhang X, Tai W, Odle AE, Perlman S, Du L. Transl Res. 2022 Oct;248:11-21. doi: 10.1016/j.trsl.2022.04.007. PMID: 35489692
• Recombinant Adeno-Associated Virus-Mediated Editing of the G551D Cystic Fibrosis Transmembrane Conductance Regulator Mutation in Ferret Airway Basal Cells.  Yan Z, Vorhies K, Feng Z, Park SY, Choi SH, Zhang Y, Winter M, Sun X, Engelhardt JF. Hum Gene Ther. 2022 Oct;33(19-20):1023-1036. doi: 10.1089/hum.2022.036.  PMID: 35686451
• Resistance training protects against muscle pain through activation of androgen receptors in male and female mice.  Lesnak JB, Fahrion A, Helton A, Rasmussen L, Andrew M, Cunard S, Huey M, Kreber A, Landon J, Siwiec T, Todd K, Frey-Law LA, Sluka KA. Pain. 2022 Oct 1;163(10):1879-1891. doi: 10.1097/j.pain.0000000000002638. PMID: 35353765
• A saturated map of common genetic variants associated with human height.  Yengo L, Vedantam S, Marouli E, et al,…..London B, 23andMe Research Team; VA Million Veteran Program; DiscovEHR (DiscovEHR and MyCode Community Health Initiative); eMERGE (Electronic Medical Records and Genomics Network); Lifelines Cohort Study; PRACTICAL Consortium; Understanding Society Scientific Group. Nature. 2022 Oct;610(7933):704-712. doi: 10.1038/s41586-022-05275-y. PMID: 36224396
• Scylla, Charybdis, and navigating antimicrobial action in the neutrophil phagosome.  Nauseef WM. J Leukoc Biol. 2022 Oct;112(4):587-589. doi: 10.1002/JLB.4CE0422-232R. PMID: 35929044
• Upper and Lower Airway Dysanapsis and Airflow Obstruction among Older Adults.  Smith BM, Wiemken A, Hoffman EA, Keenan BT, Allen NB, Bertoni AG, Jacobs DR Jr, Michos ED, Watson KE, Redline S, Schwab RJ, Barr RG, Heckbert SR. Am J Respir Crit Care Med. 2022 Oct 1;206(7):913-917. doi: 10.1164/rccm.202202-0353LE. PMID: 35679318
• Use of Fluoxetine to Augment the Inter-Ictal Hypercapnic Ventilatory Response in Patients with Epilepsy: A Pilot Study. Sainju RK, Dragon DN, Winnike HB, Eyck PT, Granner MA, Gehlbach BK, Richerson GB. Neurol India. 2022 Sep-Oct;70(5):2125-2129. doi: 10.4103/0028-3886.359160. PMID: 36352620 
• WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia.  Rehman T, Karp PH, Thurman AL, Mather SE, Jain A, Cooney AL, Sinn PL, Pezzulo AA, Duffey ME, Welsh MJ. Am J Respir Cell Mol Biol. 2022 Oct;67(4):491-502. doi: 10.1165/rcmb.2022-0172OC. PMID: 35849656