– Newly Added Paper

Dec 31

• The Interaction of Vitamin D and Corticosteroids: A Mortality Analysis of 26,508 Veterans Who Tested Positive for SARS-CoV-2.  Efird JT, Anderson EJ, Jindal C, Redding TS, Thompson AD, Press AM, Upchurch J, Williams CD, Choi YM, Suzuki A. Int J Environ Res Public Health. 2021 Dec 31;19(1):447. doi: 10.3390/ijerph19010447. PMID: 35010701

Dec 28

• A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome.  Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F. Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. PMID: 34964109

Dec 27

• Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy.  Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. J Nutr. 2021 Dec 27:nxab440. doi: 10.1093/jn/nxab440. PMID: 34958390
• Sex Differences in the Association of Pre-Transfusion Hemoglobin Levels with Brain Structure and Function in the Preterm Infant.  Benavides A, Bell EF, Conrad AL, Feldman HA, Georgieff MK, Josephson CD, Koscik T, Stowell SR, Sola-Visner M, Nopoulos P. J Pediatr. 2021 Dec 27:S0022-3476(21)01258-0. doi: 10.1016/j.jpeds.2021.12.051. PMID: 34968498
• Transforming Growth Factor-α Acts in Hypothalamic Paraventricular Nucleus to Upregulate ERK1/2 Signaling and Expression of Sympathoexcitatory Mediators in Heart Failure Rats. Yu Y, Chen E, Weiss RM, Felder RB, Wei SG. Neuroscience. 2021 Dec 27:S0306-4522(21)00654-0. doi: 10.1016/j.neuroscience.2021.12.030. PMID: 34968668

Dec 24

• Outcomes of peroral endoscopic myotomy in patients with achalasia and prior bariatric surgery: A multicenter experience.  Bomman S, Klair JS, Ashat M, El Abiad R, Gerke H, Keech J, Parekh K, Nau P, Hanada Y, Wong Kee Song LM, Kozarek R, Irani S, Low D, Ross A, Krishnamoorthi R. Dis Esophagus. 2021 Dec 24;34(12):doab044. doi: 10.1093/dote/doab044. PMID: 34184036

Dec 22

• Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2AΔ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis. Ollinger TL, Vu B, Murante D, Parker JE, Simonicova L, Doorley L, Stamnes MA, Kelly SL, Rogers PD, Moye-Rowley WS, Krysan DJ. mSphere. 2021 Dec 22;6(6):e0083021. doi: 10.1128/msphere.00830-21. Epub 2021 Dec 22. PMID: 34935446

Dec 21

• Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections.  Durfey SL, Pipavath S, Li A, Vo AT, Ratjen A, Carter S, Morgan SJ, Radey MC, Grogan B, Salipante SJ, Welsh MJ, Stoltz DA, Goss CH, McKone EF, Singh PK. mBio. 2021 Dec 21;12(6):e0314821. doi: 10.1128/mbio.03148-21. Epub 2021 Dec 14. PMID: 34903059. Clinical Trial.

Dec 20

• Associations of Monocyte Count and Other Immune Cell Types with Interstitial Lung Abnormalities.  Kim JS, Axelsson GT, Moll M, Anderson MR, Bernstein EJ, Putman RK, Hida T, Hatabu H, Hoffman EA, Raghu G, Kawut SM, Doyle MF, Tracy R, Launer LJ, Manichaikul A, Rich SS, Lederer DJ, Gudnason V, Hobbs BD, Cho MH, Hunninghake GM, Garcia CK, Gudmundsson G, Barr RG, Podolanczuk AJ. Am J Respir Crit Care Med. 2021 Dec 20. doi: 10.1164/rccm.202108-1967OC. PMID: 34929108
• Menstrual cycle impacts lung structure measures derived from quantitative computed tomography.  Sieren JC, Schroeder KE, Guo J, Asosingh K, Erzurum S, Hoffman EA. Eur Radiol. 2021 Dec 20. doi: 10.1007/s00330-021-08404-9. PMID: 34928413
• Retinal ciliopathies through the lens of Bardet-Biedl Syndrome: Past, present and future.  Chandra B, Tung ML, Hsu Y, Scheetz T, Sheffield VC. Prog Retin Eye Res. 2021 Dec 17:101035. doi: 10.1016/j.preteyeres.2021.101035. Review. PMID: 34929400

Dec 15

• Days of Antibiotic Spectrum Coverage (DASC): A Novel Metric for Inpatient Antibiotic Consumption. Kakiuchi S, Livorsi DJ, Perencevich EN, Diekema DJ, Ince D, Prasidthrathsint K, Kinn P, Percival K, Heintz BH, Goto M. Clin Infect Dis. 2021 Dec 15:ciab1034. doi: 10.1093/cid/ciab1034. PMID: 34910130

Dec 14

• Clinical characteristics of COVID-19 in solid organ transplant recipients following COVID-19 vaccination: A multicenter case series.  Saharia K, Anjan S, Streit J, Beekmann SE, Polgreen PM, Kuehnert M, Segev DL, Baddley JW, Miller RA. Transpl Infect Dis. 2021 Dec 14. doi: 10.1111/tid.13774. PMID: 34905269
• Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections.  Durfey SL, Pipavath S, Li A, Vo AT, Ratjen A, Carter S, Morgan SJ, Radey MC, Grogan B, Salipante SJ, Welsh MJ, Stoltz DA, Goss CH, McKone EF, Singh PK. mBio. 2021 Dec 14:e0314821. doi: 10.1128/mbio.03148-21. PMID: 34903059

Dec 13

• Validation of blood arsenic and manganese assessment from archived clotted erythrocyte fraction in an urban cohort of mother-child dyads.  Haque E, Moran ME, Wang H, Adamcakova-Dodd A, Thorne PS. Sci Total Environ. 2021 Dec 13;810:152320. doi: 10.1016/j.scitotenv.2021.152320. PMID: 34915002

Dec 10

• AAV-mediated gene editing lights up the lung.  Yan Z, Lynch TJ, Engelhardt JF. Mol Ther. 2021 Dec 10:S1525-0016(21)00639-0. doi: 10.1016/j.ymthe.2021.12.003. PMID: 34895514
• Analysis of Cerebral Aneurysm Wall Tension and Enhancement Using Finite Element Analysis and High-Resolution Vessel Wall Imaging.  Galloy AE, Raghuram A, Nino MA, Varon Miller A, Sabotin R, Osorno-Cruz C, Samaniego EA, Raghavan SML, Hasan D. Front Neurol. 2021 Dec 10;12:764063. doi: 10.3389/fneur.2021.764063. PMID: 34956050

Dec 9

• Analgesic use and circulating estrogens, androgens, and their metabolites in the Women's Health Initiative Observational Study.  Hurwitz LM, Shadyab AH, Tabung FK, Anderson GL, Saquib N, Wallace RB, Wild RA, Pfeiffer RM, Xu X, Trabert B. Cancer Prev Res (Phila). 2021 Dec 9:canprevres.CAPR-21-0264-A.2021. doi: 10.1158/1940-6207.CAPR-21-0264. PMID: 34893532

Dec 8

• Effect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial.  Driver BE, Semler MW, Self WH, Ginde AA, Trent SA, Gandotra S, Smith LM, Page DB, Vonderhaar DJ, West JR, Joffe AM, Mitchell SH, Doerschug KC, Hughes CG, High K, Landsperger JS, Jackson KE, Howell MP, Robison SW, Gaillard JP, Whitson MR, Barnes CM, Latimer AJ, Koppurapu VS, Alvis BD, Russell DW, Gibbs KW, Wang L, Lindsell CJ, Janz DR, Rice TW, Prekker ME, Casey JD; BOUGIE Investigators and the Pragmatic Critical Care Research Group. JAMA. 2021 Dec 8. doi: 10.1001/jama.2021.22002. PMID: 34879143
• Human miRNA miR-675 inhibits DUX4 expression and may be exploited as a potential treatment for Facioscapulohumeral muscular dystrophy.  Saad NY, Al-Kharsan M, Garwick-Coppens SE, Chermahini GA, Harper MA, Palo A, Boudreau RL, Harper SQ. Nat Commun. 2021 Dec 8;12(1):7128. doi: 10.1038/s41467-021-27430-1. PMID: 34880230
• Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform.  Strub MD, Ramachandran S, Boudko DY, Meleshkevitch EA, Pezzulo AA, Subramanian A, Liberzon A, Bridges RJ, McCray PB Jr. CPT Pharmacometrics Syst Pharmacol. 2021 Dec 8. doi: 10.1002/psp4.12751. PMID: 34877817

Dec 7

• Protein profiling of RGS6, a pleiotropic gene implicated in numerous neuropsychiatric disorders, reveals multi-isoformic expression and a novel brain-specific isoform.  Ahlers-Dannen KE, Yang J, Spicer MM, Maity B, Stewart A, Koland JG, Fisher RA. eNeuro. 2021 Dec 7:ENEURO.0379-21.2021. doi: 10.1523/ENEURO.0379-21.2021. PMID: 34880111

Dec 6

• BBSome: a New Player in Hypertension and Other Cardiovascular Risks.  Zhao Y, Rahmouni K. Hypertension. 2021 Dec 6:HYPERTENSIONAHA12117946. doi: 10.1161/HYPERTENSIONAHA.121.17946. PMID: 34865504

Dec 5

• Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.  Dampalla CS, Rathnayake AD, Perera KD, Jesri AM, Nguyen HN, Miller MJ, Thurman HA, Zheng J, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Kim Y, Groutas WC, Chang KO. J Med Chem. 2021 Dec 5. doi: 10.1021/acs.jmedchem.1c01037. PMID: 34865476

Dec 3

• Using nasal povidone-iodine to prevent bloodstream infections and transmission of Staphylococcus aureus among haemodialysis patients: a stepped-wedge cluster randomised control trial protocol.  Racila AM, O'Shea AMJ, Nair R, Dukes K, Herwaldt LA, Boyken L, Diekema D, Ward MA, Cobb J, Jacob J, Pegues D, Bleasdale S, Vijayan A, Mutneja A, Fraer M, O'Connell-Moore D, Tolomeo P, Mendez M, Jaworski E, Schweizer ML. BMJ Open. 2021 Dec 3;11(12):e048830. doi: 10.1136/bmjopen-2021-048830. PMID: 34862278

Dec 2

• The impact of KRAS mutation, microsatellite instability, and tumor laterality on the prognosis of nonmetastatic colon cancer.  Tran CG, Goffredo P, Mott SL, Hart A, You YN, Vauthey JN, Weigel RJ, Hassan I. Surgery. 2021 Dec 2:S0039-6060(21)01044-8. doi: 10.1016/j.surg.2021.10.043. PMID: 34865865

Dec 1

• A "Failed" Assay Development for the Discovery of Rescuing Small Molecules from the Radiation Damage.  Wen KK, Roy S, Grumbach IM, Wu M. SLAS Discov. 2021 Dec;26(10):1315-1325. doi: 10.1177/24725552211020678. PMID: 34151632
• Albuminuria as a Predictor of Mortality from Chronic Lower Respiratory Disease and from Influenza and Pneumonia.  Mendy A, Salo PM, Wilkerson J, Feinstein L, Fessler MB, Thorne PS, Zeldin DC. Ann Am Thorac Soc. 2021 Dec;18(12):2093-2095. doi: 10.1513/AnnalsATS.202009-1226RL. PMID: 33979561
• ASO Visual Abstract: Surgical Decision-Making Surrounding Contralateral Prophylactic Mastectomy: Comparison of Treatment Goals, Preferences, and Psychosocial Outcomes from a Multicenter Survey of Breast Cancer Patients.  Lizarraga IM, Schroeder MC, Jatoi I, Sugg SL, Trentham-Dietz A, Hoeth L, Chrischilles EA. Ann Surg Oncol. 2021 Dec;28(Suppl 3):546-547. doi: 10.1245/s10434-021-10483-3. PMID: 34275044
• AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning. Deng W, Hedberg-Buenz A, Soukup DA, Taghizadeh S, Wang K, Anderson MG, Garvin MK. Transl Vis Sci Technol. 2021 Dec 1;10(14):22. doi: 10.1167/tvst.10.14.22. PMID: 34932117
• Development of a Single-cycle Infectious SARS-CoV-2 Virus Replicon Particle System for use in BSL2 Laboratories.  Malicoat J, Manivasagam S, Zuñiga S, Sola I, McCabe D, Rong L, Perlman S, Enjuanes L, Manicassamy B. J Virol. 2021 Dec 1:JVI0183721. doi: 10.1128/JVI.01837-21. PMID: 34851142
• Exploring experiences of hypertrophic cardiomyopathy diagnosis, treatment, and impacts on quality of life among middle-aged and older adults: An interview study.  Zytnick D, Heard D, Ahmad F, Cresci S, Owens AT, Shay CM. Heart Lung. 2021 Nov-Dec;50(6):788-793. doi: 10.1016/j.hrtlng.2021.06.004. PMID: 34225089
• High-resolution vessel wall imaging after mechanical thrombectomy.  Kasab SA, Bathla G, Varon A, Roa JA, Sabotin R, Raghuram A, Chaorong W, Hasan DM, Turan TN, Chatterjee R, Samaniego EA. Neuroradiol J. 2021 Dec;34(6):593-599. doi: 10.1177/19714009211017782. PMID: 34014780
• Insights into the pathogenesis of cerebral fusiform aneurysms: high-resolution MRI and computational analysis.  Sabotin RP, Varon A, Roa JA, Raghuram A, Ishii D, Nino M, Galloy AE, Patel D, Raghavan ML, Hasan D, Samaniego EA. J Neurointerv Surg. 2021 Dec;13(12):1180-1186. doi: 10.1136/neurintsurg-2020-017243. PMID: 33632878
• Intra- and Interobserver Reliability of the New Classification System of Progressive Collapsing Foot Deformity.  Lee HY, Barbachan Mansur NS, Lalevee M, Dibbern KN, Myerson MS, Ellis SJ, Femino JE; Progressive Collapsing Foot Deformity Consensus Group, de Cesar Netto C. Foot Ankle Int. 2021 Dec 1:10711007211058154. doi: 10.1177/10711007211058154.  PMID: 34852647
• Medical Education and the Ethics of Self-Care: A Survey of Medical Students Regarding Professional Challenges and Expectations for Living Healthy Lifestyles.  Rempel AML, Barlow PB, Kaldjian LC. South Med J. 2021 Dec;114(12):783-788. doi: 10.14423/SMJ.0000000000001333. PMID: 34853855
• Pulmonary fibrosis 4 months after COVID-19 is associated with severity of illness and blood leucocyte telomere length.  McGroder CF, Zhang D, Choudhury MA, Salvatore MM, D'Souza BM, Hoffman EA, Wei Y, Baldwin MR, Garcia CK. Thorax. 2021 Dec;76(12):1242-1245. doi: 10.1136/thoraxjnl-2021-217031. PMID: 33927016
• Surgical Decision-Making Surrounding Contralateral Prophylactic Mastectomy: Comparison of Treatment Goals, Preferences, and Psychosocial Outcomes from a Multicenter Survey of Breast Cancer Patients.  Lizarraga IM, Schroeder MC, Jatoi I, Sugg SL, Trentham-Dietz A, Hoeth L, Chrischilles EA. Ann Surg Oncol 2021 Dec;28(13):8752-8765.doi:10.1245/s10434-021-10426-y. PMID: 34251554