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For Participants

Thank you for your interest in PReventing Emerging Infections through Vaccine EffectiveNess Testing (Project PREVENT). PREVENT is public health surveillance project  being conducted at 16 U.S. hospitals to measure the effectiveness of the COVID-19 vaccines. This project is being funded by the Centers for Disease Control and Prevention (CDC). 

If you are a health care worker, you have been recently tested for COVID-19, and your hospital is participating, you may qualify to participate in Project PREVENT. You do not need to have received a COVID-19 vaccine and you do not need to have a positive COVID-19 test.  If you qualify for the project, you will not be given any vaccines or treatments. We will ask you to complete two surveys about your illness, your exposures, vaccines you have received, and your health care visits. 

What are you hoping to learn through Project PREVENT?

We want to learn how COVID-19 vaccines work. The reason we are enrolling health care personnel is because we anticipate that they will be among the groups prioritized to receive COVID-19 vaccine first. That will give us a chance to learn from the experience in health care personnel to better understand how people respond to the vaccine.

We will learn:

  1. How well available COVID-19 vaccine(s) protect health care personnel from developing symptomatic laboratory-confirmed COVID-19;
  2. How well available COVID-19 vaccine(s) protect health care personnel from developing severe COVID-19 infection;
  3. How different age groups and risk groups are protected by the COVID-19 vaccine;
  4. How testing, isolation, and return-to-work practices vary in the pandemic;
  5. How health care personnel decide whether to get the COVID-19 vaccine; and
  6. How vaccination is associated with health care personnel infection prevention decision-making in the context of the pandemic.

What are the risks to participating in Project PREVENT?

Because there are no experimental treatments or procedures as part of your participation, the only risk is that you are giving us access to your private health information so that we can learn how to better protect other health care personnel in the future. However, we will keep your private health information confidential and secure.

You will not receive any vaccines as part of your participation in Project PREVENT.

What do you mean by access to my private health information?

For Project PREVENT, we will get copies of your vaccination records, your testing records, and any medical records for visits related to your recent/current illness.  These records will be requested only with your permission, and they will be maintained on a secure password-protected server accessible only to the project team. We will only collect the minimum amount of data we need to answer our project question, and we will not disclose the results to your employer or anyone else outside the project team.

What will you do with the results of your project?

We will share de-identified data (meaning data without your name or any other identifying information) with the Centers for Disease Control and Prevention (CDC) for them to pool with other studies to measure vaccine effectiveness.  Your results will be combined with other participants’ results, and we will use the data to write papers in medical journals so that other health care professionals can learn more about how the COVID-19 vaccines work. You will not be individually identifiable in any of these reports.

Will I be compensated for my participation?

You will be compensated $25 each for completing 2 online or telephone surveys for Project PREVENT.  We anticipate that the first survey will take 20 minutes and the second survey will take 10 minutes to complete.

How will I know if I was selected to participate?

If you are selected to participate, you will receive an e-mail inviting you to complete a screening questionnaire.

What if I participated in a vaccination trial previously?

That’s okay.  You can participate in Project PREVENT even if you were a participant in one of the vaccine clinical trials.

What exactly do I need to do if I want to participate?

You may only participate if you are a health care worker at one of the 16 participating site hospitals and were recently tested for COVID-19 and had symptoms within 2 weeks of your COVID-19 test. If you reported your results to your employee health department, you may receive an email inviting you to participate. If you did not report your test results to your employee health clinic and are interested in participating, please complete this interest form.

When you receive an e-mail inviting you to participate, you will be asked to click on a link to a survey asking a few questions to make sure that you are eligible for the project. If you are eligible, then you will complete a consent form to tell us you agree to participate in the project. After that form, you will complete a baseline enrollment survey, which takes about 20 minutes. You will provide some details about where you received COVID-19 testing, vaccinations, and medical care for your current/recent illness. The details you provide will allow you to give us permission to get copies of your records from employee health clinics, doctor’s offices, or hospitals.  We will never request records without your permission, though.  After you finish your first survey, we will mail you a check for $25 to compensate you for your time.

At about 6 weeks after your symptoms first started, you will receive an e-mail and a text message to invite you to complete your final survey. That survey will take about 10 minutes.  After you complete that survey, your participation in the project is complete, and you will receive another check for $25.

What if I decide I do not want to participate?

You may decline to participate at the beginning of the project, or you may drop out at any time. We encourage all of our participants to try to complete the project, so that we can learn as much as we can about the effectiveness of COVID-19 vaccines.

Who is leading this project?

Project PREVENT is a collaborative project between doctors at 16 participating U.S. medical centers, the coordinating centers at the University of Iowa and UCLA Medical Center, and the CDC. You can learn more about our Study Team.

What if I have questions?

If you have questions, please feel free to contact the project team by e-mail at EmergencyIDNet-PREVENT@uiowa.edu.