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ARVO 2017 Schedule

ARVO 2017

ARVO Annual Meeting. May 7-11, 2017, Baltimore, MD

Presentations and Posters

from The University of Iowa Department of Ophthalmology & Visual Sciences

Don’t miss our presentations and posters at ARVO. Below is a list of the various offerings from our researchers. We look forward to seeing you.

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Iowa Eye Reception will be held on Sunday, May 7 from 7:30-9:30 PM | More info: https://goo.gl/4rAI5V


Sunday

5/7/2017, 8:30 AM – 8:47 AM. Randy Kardon*, New Approaches for Assessing the Short and Long Term Effects of Trauma on the Visual System. Special Session: “Eyes and Vision Trauma.” Location: Room 316

5/7/2017, 8:30 AM - 10:15 AM. Lorenzo Lones*, Erin Burnight, Dalyz Ochoa, Joseph Giacalone, Robert Madumba, Robert Mullins, Edwin Stone, Budd Tucker, Luke Wiley, Using pathway-specific reporter and direct conversion constructs to investigate Juvenile Neuronal Ceroid Lipofuscinosis. Session: “Retinal degeneration. Models and mechanisms.” Poster #B0316 Abstract #263. Location: Exhibit/Poster Hall.

5/7/2017, 1:30 PM - 3:15 PM. James Peairs*, Michael Abramoff, Kyungmoo Lee, Zhihui Guo, Douglas Critser, James Folk, OCT- Predictive Visual Threshold Sensitivity Predicts Visual Field Loss in Patients with Ocular Inflammatory Disease. Session: “Uveitis therapeutics: remedy and Relief.” Poster #B0057 Abstract #502. Location: Exhibit/Poster Hall.

5/7/2017, 1:30 PM - 3:15 PM. Robert Mullins*, S Scott Whitmore, Kathleen Chirco, Grefachew Workalemahu, Shemin Zeng, Adam DeLuca, XiuYing Liu, Jessica Penticoff, Luke Wiley, Edwin Stone, Budd Tucker, The human RPE-choroid in short term organ culture: evaluation of gene expression changes. Session: “Biochemistry and molecular biology of the retina.” Poster #B0187 Abstract #619. Location: Exhibit/Poster Hall.

5/7/2017, 1:30 PM - 3:15 PM. Jean-Claude Mwanza*, Gary Lee, Joshua Warren, John Flanagan, Paul Artes, Michael Wall, Thomas Callan, Donald Budenz, Validation of the Performance of the UNC Optical Coherence Tomography Index for Early Glaucoma Diagnosis. Session: “Imaging: Macula Retina, Blood Flow, OCT Angiography.” Poster #B0452 Abstract #705. Location: Exhibit/Poster Hall.

5/7/2017, 3:15 PM - 5:00 PM. Kyungmoo Lee*, Ian Han, Douglas Critser, Andreas Wahle, Milan Sonka, Michael Abramoff, Layer-Specific Vascular Analysis of OCT Angiography in Diabetic Macular Edema. Session: “Image Processing and Interpretation.” Poster #B0391 Abstract #644. Location: Exhibit/Poster Hall.

5/7/2017, 3:15 PM - 5:00 PM. Beerend Winkelman*, Johanna Maria Colijn, Pieter Bonnemaijer, Fernanda Fujihara, Michael Abramoff, Kristine Lee, Anthony Fairbanks, Stacy Meuer, Barbara Klein, Ronald Klein, Caroline Klaver, Retinal layer segmentation results differ between two generations of OCT devices. Session: “Image Processing and Interpretation.” Poster #B0419 Abstract #672. Location: Exhibit/Poster Hall.

5/7/2017, 4:15 PM - 4:30 PM. S Scott Whitmore*, Kyungmoo Lee, Adam DeLuca, Young Kwon, Jeremy Hoffman, Jennifer Halder, Robert Mullins, Todd Scheetz, Edwin Stone, Michael Abramoff, How to Distill Disease-Differentiating, Quantitative Phenotypic Patterns from OCT Data. Session: “Deep learning for image segmentation and classification.” Presentation #826 Abstract #826. Location: Room 301.

5/7/17, 7:30 PM - 9:30 PM. ARVO Meeting - Iowa Eye Reception. Forno Restaurant - 17 N. Eutaw Street, Baltimore, MD, 21201.https://www.fornobaltimore.com. To RSVP or for questions, contact Joe Schmidt, joe-schmidt@uiowa.edu or 319-384-8529.

*presenter

Monday

5/8/2017, 8:30 AM - 10:15 AM. Luke Wiley*, Laura Bohrer, Erin Burnight, Elizabeth Kennedy, Edwin Stone, Mark Greiner, Michael Wagoner, Budd Tucker, Development of corneal endothelial cell-specific reporter constructs and a CRISPR-Cas9 genome editing approach to study Fuchs Dystrophy.. Session: “Corneal Endothelium.” Poster #B0094 Abstract #1444. Location: Exhibit/Poster Hall.

5/8/2017, 11:00 AM - 12:45 PM. Prashant Parekh*, James Folk, Stephen Russell, Elliott Sohn, Michael Abramoff, Does fluorescein angiography add value in the management of suspected choroidal neovascularization?. Session: “Clinical retinal imaging 1.” Poster #B0329 Abstract #1857. Location: Exhibit/Poster Hall.

5/8/2017, 1:00 PM - 2:30 PM. Frank Proudlock, Arlene Drack, Joseph Carroll, Murray Brilliant*, Helena Lee, Brian Brooks, Controversies in Albinism - Why is Their Vision Poor and How Do We Fix It?. - SIG. Location: Room 324.

5/8/2017, 3:45 PM - 5:30 PM. Carly Lewis*, Jason Kam, Todd Scheetz, Ben Roos, Edwin Stone, Cheryl Khanna, Kazuhide Kawase, Robert Ritch, Andrew Lotery, Sobha Sivaprasad, Jessica Cooke Bailey, Louis Pasquale, Janey Wiggs, Young Kwon, Wallace Alward, John Fingert, The myocilin GLN368Stop mutation in normal tension glaucoma. Session: “Genetics of glaucoma.” Poster #A0233 Abstract #2127. Location: Exhibit/Poster Hall.

5/8/2017, 3:45 PM - 5:30 PM. Lorraine Provencher*, Aaron Fairbanks, Nasreen Syed, Investigating the clinical value of urine β2-microglobulin (Uβ2M) in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome. Session: “Uveitis: Diagnosis, Epidemiology, Quality of Life.” Poster #A0294 Abstract #2188. Location: Exhibit/Poster Hall.

5/8/2017, 5:15 PM - 5:30 PM. Mark Yorek*, Randy Kardon, Decreased Cornea Sensation and Loss of Corneal Nerves after Chronic Hyperglycemia is Reversible with Combination Therapy Consisting of Menhaden Oil, α-Lipoic Acid and Enalapril. Session: “Corneal immunology and neuropathy.” Presentation #2070 Abstract #2070. Location: Room 321.

*presenter

Tuesday

5/9/2017, 8:30 AM - 10:15 AM. Steffi Daniel*, Michael Anderson, Abbot Clark, Colleen McDowell, RGC subtype specific death in acute and chronic models of glaucoma. Session: “Neurodegeneration and Neuroprotection.” Poster #A0132 Abstract #2542. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 10:15 AM. Adam DeLuca*, Heather Daggett, Jade East, Arlene Drack, Todd Scheetz, Val Sheffield, Edwin Stone, Whole genome sequencing to find missing alleles in patients with retinal disease.. Session: “Whole Genome Analysis, Genetic Screening in Retinal Dystrophies and Others.” Poster #B0083 Abstract #2756. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 10:15 AM. Scott Brodie*, Arlene Drack, Edwin Stone, Severe congenital stationary night blindness due to GUCY2D mutations. Session: “Whole Genome Analysis, Genetic Screening in Retinal Dystrophies and Others.” Poster #B0100 Abstract #2773. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 10:15 AM. Kent Small*, Fadi Shaya, Svetlana Yelchits, Adam DeLuca, Richard Lewis, Monique Leys, Nitin Udar, Benjamin Bakall, Klaus Rohrschneider, Bernard Puech, Virginie Puech, Elise Heon, James Folk, Gerald Fishman, Christine Garabetian, Edwin Stone, North Carolina macular dystrophy: mutations found in 12 additional families. Session: “Whole Genome Analysis, Genetic Screening in Retinal Dystrophies and Others.” Poster #B0106 Abstract #2779. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 10:15 AM. Luke Chong*, Paul Artes, Michael Wall, Thomas Callan, Vincent Michael Patella, Gary Lee, Matthias Monhart, John Flanagan, Perimetric Threshold Predictability Between Goldmann Size III and V Stimuli. Session: “Visual Fields, Vision Function, Psychophysics I.” Poster #B0445 Abstract #2842. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 10:15 AM. Michael Wall*, K Zamba, Paul Artes, The Effective Dynamic Ranges for Visual Field Progression with Standard Automated Perimetry with Stimulus Sizes III and V. Session: “Visual Fields, Vision Function, Psychophysics I.” Poster #B0463 Abstract #2860. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 10:15 AM. Barbara Klein*, Kayla Horak, Kristine Lee, Stacy Meuer, Michael Abramoff, Elsayed Soliman, Mary Rechek, Ronald Klein, Associations of peripheral sensory, autonomic and anatomic neural characteristics and proliferative retinopathy in persons with type 1 diabetes. Session: “Diabetic Eye Disease.” Poster #B0536 Abstract #2890. Location: Exhibit/Poster Hall.

5/9/2017, 8:30 AM - 8:35 AM. Elliott Sohn*, Introduction to minisymposium: Novel therapies and imaging techniques for retinal disorders. Session: “Novel therapies and imaging techniques for retinal disorders - Minisymposium.” Minisymposium Presentation #2466 Abstract #. Location: Hall G.

5/9/2017, 8:30 AM - 8:45 AM. Todd Scheetz*, Adam DeLuca, Nicole Tatro, Benjamin Faga, Douglas Oppedal, Meagan Luse, Richard Weleber, Edwin Stone, Symmetry of inherited eye disease. Session: “The Impact of Low Vision on Function and Everyday Activities.” Presentation #2479 Abstract #2479. Location: Room 308.

5/9/2017, 8:35 AM - 8:52 AM. Budd Tucker*, Patient specific stem cell therapy for inherited retinal diseases. Session: “Novel therapies and imaging techniques for retinal disorders - Minisymposium.” Presentation #2467 Abstract #2467. Location: Hall G.

5/9/2017, 11:00 AM - 12:45 PM. Randy Kardon*, Cole Starkey, Jan Full, Anna Ketcham, Brian Tong, Gary Pierce, Seth Holwerda, Jess Fiedorowicz, Human Retinal Vascular Reactivity to Flickering Light and Cold Water Immersion Measured by Laser Speckle Flowgraphy. Session: “Blood flow.” Poster #A0038 Abstract #3043. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Christine Sindt*, Bruno Lay, Ronan Danno, David Slater, Modeling the limbus as an elliptical toric to optimize scleral lens fitting. Session: “Contact Lenses.” Poster #A0334 Abstract #3080. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Bruno Lay*, Christine Sindt, David Slater, Normative Scleral Lens Landing Data. Session: “Contact Lenses.” Poster #A0335 Abstract #3081. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Kasra Zarei*, Pieter Poolman, Mona Garvin, Randy Kardon, eyeFusion: Mobile, Objective Quantification of Critical Flicker Fusion Thresholds. Session: “Innovations in imaging.” Poster #B0032 Abstract #3129. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Jesse Sengillo*, Thiago Cabral, Kaspar Schuerch, Jimmy Duong, Winston Lee, Katherine Boudreault, Sally Justus, Yu Xu, Janet Sparrow, Vinit Mahajan, Stephen Tsang, Hearing Loss as a Prognostic Indicator of Visual Function in USH2A-associated Retinal Degeneration.. Session: “Retinitis pigmentosa (clinical).” Poster #B0356 Abstract #3223. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Daniel Chung*, Stephen Russell, Jean Bennett, Albert Maguire, Jennifer Wellman, Zi-Fan Yu, Amy Tillman, Katherine High, Correlation of multi-luminance mobility testing with visual function tests in a phase 3 trial of voretigene neparvovec for biallelic RPE65-mediated inherited retinal disease. Session: “Functioning with Low Vision.” Poster #B0425 Abstract #3292. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Eric Lee*, Ashwin Subramani, Robert Wanzek, Trina Eden, Luke Chong, Andrew Turpin, Ivan Marin-Franch, Michael Wall, Patterns of Vision Loss in Idiopathic Intracranial Hypertension: The Central vs. Peripheral Visual Field. Session: “Papilledema, IIH and Optic Nerve.” Poster #B0590 Abstract #3314. Location: Exhibit/Poster Hall.

5/9/2017, 11:00 AM - 12:45 PM. Ashwin Subramani*, Michael Wall, Eric Lee, Andrew Turpin, Luke Chong, Detection of Visual Loss in Idiopathic Intracranial Hypertension with Static Automated Perimetry: The Far Periphery. Session: “Papilledema, IIH and Optic Nerve.” Poster #B0591 Abstract #3315. Location: Exhibit/Poster Hall.

5/9/2017, 1:00 PM - 2:30 PM. Michael Simpson, Chris Johnson, James Wolffsohn, Paul Artes, Far peripheral vision: Review vision beyond 80o, where many people don’t notice if there is a loss, but some intraocular lens patients report dark shadows - SIG. Location: Ballroom 4.

5/9/2017, 1:11 PM - 1:21 PM. Randy Kardon*, What makes a productive mentor - mentee relationship. Session: “Clinician-scientist forum: How to become a successful clinician-scientist.” Forum Abstract #. Location: Room 316.

5/9/2017, 3:45 PM - 5:30 PM. Louise Sclafani*, David Slater, Bruno Lay, Christine Sindt, Topographic Elevation Data to Design Scleral Lenses. Session: “Corneal Imaging, Topography, and Keratoconus.” Poster #A0403 Abstract #3550. Location: Exhibit/Poster Hall.

5/9/2017, 3:45 PM - 5:30 PM. Wesley Goar*, Pierre Majdalani, Charles Searby, S Scott Whitmore, Adam DeLuca, Ahed Imtirat, Edwin Stone, Ruti Pavari, Todd Scheetz, Val Sheffield, Exome sequencing analysis in three Bedouin families with Keratoconus. Session: “Corneal Imaging, Topography, and Keratoconus.” Poster #A0409 Abstract #3556. Location: Exhibit/Poster Hall.

5/9/2017, 3:45 PM - 5:30 PM. James Folk. Session: "AMD Imaging II and Visual Function." Presentation #366. Location: Hall G.

5/9/2017, 5:00 PM - 5:15 PM. Kristan Worthington*, Jessica Thompson, Brian Green, Spencer Bunn, Emily Kaalberg, Rebecca Johnston, Luke Wiley, Robert Mullins, Edwin Stone, C Guymon, Budd Tucker, Two-Photon Polymerization of High-Resolution 3D, Biodegradable Photoreceptor Cell Scaffolds. Session: “Retinal gene therapy and stem cell transplantation.” Presentation #3390 Abstract #3390. Location: Ballroom 3.

*presenter

Wednesday

5/10/2017, 8:30 AM - 10:15 AM. Stephen Russell*, Jean Bennett, Jennifer Wellman, Daniel Chung, Katherine High, Zi-Fan Yu, Amy Tillman, Albert Maguire, Year 2 results for a phase 3 trial of voretigene neparvovec in biallelic RPE65-mediated inherited retinal disease. Session: “Drug and gene therapy and delivery.” Poster #B0122 Abstract #4122. Location: Exhibit/Poster Hall.

5/10/2017, 8:45 AM - 9:00 AM. Stephanie Lynch*, Abhay Shah, James Folk, Xiaodong Wu, Michael Abramoff, Catastrophic Failure in Image-Based Convolutional Neural Network Algorithms for Detecting Diabetic Retinopathy. Session: “Diabetic retinal imaging.” Presentation #3776 Abstract #3776. Location: Hall G.

5/10/2017, 9:30 AM - 9:45 AM. Ankur Jain*, Wei Zhu, Qihong Zhang, Markus Kuehn, Abbot Clark, Val Sheffield, Role of Primary Cilia in Trabecular Meshwork Cell Function. Session: “Trabecular Meshwork, Ciliary Body and Anterior Segment Imaging.” Presentation #3772 Abstract #3772. Location: Ballroom 4.

5/10/2017, 10:00 AM - 10:15 AM. Wei Zhu*, Emmanuel Buys, Markus Kuehn, Transplantation of iPSC-TM decreases IOP in aged sGC-/- mice. Session: “Trabecular Meshwork, Ciliary Body and Anterior Segment Imaging.” Presentation #3774 Abstract #3774. Location: Ballroom 4.

5/10/2017, 11:00 AM - 12:45 PM. Joseph Giacalone*, Luke Wiley, Erin Burnight, Jeaneen Andorf, Luan Streb, Louisa Affatigato, Cathryn Cranston, Dalyz Ochoa, Robert Mullins, Budd Tucker, Edwin Stone, Characterization and Treatment of RPGR-associated Photoreceptor Disease. Session: “Genetics of retinal dystrophies and Functional Analysis.” Poster #B0170 Abstract #1209. Location: Exhibit/Poster Hall.

5/10/2017, 11:00 AM - 12:45 PM. Brittni Scruggs*, Erin Burnight, Chunhua Jiao, Luke Wiley, Robert Mullins, Edwin Stone, Budd Tucker, Elliott Sohn, Transduction of photoreceptors following subretinal injections of AAV5 and helper-dependent adenovirus in human retina ex vivo and pig retina in vivo. Session: “Photoreceptor degeneration and retinal rescue strategies.” Poster #B0189 Abstract #4534. Location: Exhibit/Poster Hall.

5/10/2017, 11:00 AM - 12:45 PM. Ying Hsu*, Janelle Garrison, Poppy Datta, Gunhee Kim, Darryl Nishimura, Charles Searby, Seongjin Seo, Val Sheffield, Photoreceptors show age-dependent ability to regain function after restoration of target gene expression in mouse models of Bardet Biedl Syndrome. Session: “Photoreceptor degeneration and retinal rescue strategies.” Poster #B0197 Abstract #4542. Location: Exhibit/Poster Hall.

5/10/2017, 11:00 AM - 12:45 PM. Elliott Sohn*, Kristan Worthington, Chunhua Jiao, Emily Kaalberg, Stephen Russell, Katherine Gibson-Corley, Robert Mullins, Edwin Stone, Budd Tucker, Compatibility of a biodegradable retinal cell graft for the treatment of retinal degenerative blindness. Session: “Stem cells and tissue engineering for retinal repair.” Poster #B0240 Abstract #4585. Location: Exhibit/Poster Hall.

5/10/2017, 11:00 AM - 12:45 PM. Kathleen Chirco*, Kristan Worthington, Miles Flamme-Wiese, Megan Riker, Allison Songstad, Malia Collins, Joshua Andrade, Beatrix Ueberheide, Edwin Stone, Budd Tucker, Robert Mullins, Preparation of Human Choroidal ECM Scaffolds to Study Cell Replacement Strategies. Session: “Stem cells and tissue engineering for retinal repair.” Poster #B0241 Abstract #4586. Location: Exhibit/Poster Hall.

5/10/2017, 11:00 AM - 12:45 PM. Ramesh Kasetti*, Prabhavathi Maddineni, Pinkal Patel, J Cameron Millar, Tien Phan, Charles Searby, Abbot Clark, Val Sheffield, Gulab Zode, Inhibition of Transforming Growth Factor-β2 Signaling Prevents ECM Remodeling, Endoplasmic Reticulum Stress and Ocular Hypertension in Steroid-induced Glaucoma. Session: “Pharmacological Intervention and Cellular Mechanisms.” Poster #B0304 Abstract #4603. Location: Exhibit/Poster Hall.

5/10/2017, 12:00 PM - 12:15 PM. Jui-Kai Wang*, Caitlin Danielson, Randy Kardon, Patrick Sibony, Mark Kupersmith, Mona Garvin, Three-Dimensional Bruch’s Membrane Shape Change Over Time with Acetazolamide Treatment in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). Session: “Intracranial Hypertension and Optic Nerve Changes.” Presentation #4308 Abstract #4308. Location: Room 324.

5/10/2017, 1:00 PM - 2:30 PM. Michael Abramoff, Florence Thng, Glenn Jaffe, Steven Tolle, Kaushal Solanki; Michael Abramoff, moderator, Update on Automated Screening for Diabetic Retinopathy: Validation and Implementation. - SIG. Location: Ballroom 1.

5/10/2017, 3:45 PM - 5:30 PM. Benjamin Aldrich*, Jessica Skeie, Gregory Schmidt, Cynthia Reed, Markus Kuehn, Mark Greiner, Proteomic Analysis of Aqueous Humor Reveals Progression of Diabetes Mellitus in the Anterior Chamber. Session: “Cornea and Anterior Chamber.” Poster #A0097 Abstract #4814. Location: Exhibit/Poster Hall.

5/10/2017, 3:45 PM - 5:30 PM. Oliver Gramlich*, Dina Ahram, Markus Kuehn, Expression of fibrotic and inflammation markers in the human glaucomatous optic nerve head. Session: “Glaucoma: Biochemical and molecular disease mechanisms.” Poster #B0336 Abstract #4918. Location: Exhibit/Poster Hall.

*presenter

Thursday

5/11/2017, 8:30 AM - 10:15 AM. Chunhua Jiao*, Michael Abramoff, Kyungmoo Lee, Ipek Oguz, Peter Adamson, Adam Hedberg-Buenz, Michael Anderson, Elliott Sohn, Diabetes induced neurodegeneration in the retina and the brain of mice are associated and independent of microvasculopathy. Session: “Diabetic Retinopathy: Neurodegeneration and pathology associated with the neurovascular unit..” Poster #B0082 Abstract #5195. Location: Exhibit/Poster Hall.

5/11/2017, 9:05 AM - 9:20 AM. John Fingert*, Autophagy genes and new insights into the pathogenesis and treatment of glaucoma. Session: “Genes and disease: How knowledge of genetics can guide treatment, now and in the future.” Presentation #5104 Abstract #5104. Location: Ballroom 3.

5/11/2017, 11:30 AM - 1:15 PM. Theofilos Tourtas*, Friedrich Kruse, Benjamin Aldrich, Julia Weller, Jessica Skeie, Gregory Schmidt, Cynthia Reed, Mark Greiner, Ursula Schlotzer-Schrehardt, Structural and biochemical alterations of the posterior cornea associated with diabetes mellitus. Session: “Corneal Non-refractive Surgery.” Poster #B0207 Abstract #5704. Location: Exhibit/Poster Hall.

5/11/2017, 11:30 AM - 1:15 PM. Zhihui Guo*, Young Kwon, Kyungmoo Lee, Kai Wang, Chris Johnson, Mona Garvin, Milan Sonka, Michael Abramoff, Optical Coherence Tomography analysis based prediction of Humphrey 24-2 visual field thresholds in patients with glaucoma. Session: “Structure-Function Relationships II.” Poster #B0380 Abstract #5828. Location: Exhibit/Poster Hall.

5/11/2017, 11:45 AM - 12:00 PM. John Chen*, Jacqueline Leavitt, Jackson Abou Chehade, Raymond Iezzi, David Hodge, Randy Kardon, A comparison of optic neuritis and NAION with OCT and OCT angiography. Session: “Retinal Abnormalities and Neuropathology.” Presentation #5642 Abstract #5642. Location: Room 324.

5/11/2017, 12:45 PM - 1:00 PM. Tasneem Sharma*, Joseph Giacalone, Erin Burnight, Kristin Anfinson, Jill Wiley, John Fingert, Robert Mullins, Edwin Stone, Budd Tucker, Combining CRISPR based genome editing and patient specific iPSCs to elucidate the pathophysiologic role of WFS1 mutations in optic atrophy.. Session: “Novel methods and Mechanisms of Disease.” Presentation #5585 Abstract #5585. Location: Ballroom 4.

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Date: 
Thursday, April 6, 2017